Guide to the Human Genome
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Search of human proteins with 7108344

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7108344 granulysin isoform NKG5 [Homo sapiens]
         (145 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7108344 granulysin isoform NKG5 [Homo sapiens]                     297   2e-81
gi|157502222 granulysin isoform 519 [Homo sapiens]                    265   1e-71
gi|145977198 prosaposin-like protein 1 [Homo sapiens]                  34   0.049
gi|110224479 prosaposin isoform c preproprotein [Homo sapiens]         30   0.71 
gi|110224476 prosaposin isoform b preproprotein [Homo sapiens]         30   0.71 
gi|11386147 prosaposin isoform a preproprotein [Homo sapiens]          30   0.71 
gi|239754072 PREDICTED: hypothetical protein [Homo sapiens]            29   1.6  
gi|190343010 SP110 nuclear body protein isoform a [Homo sapiens]       28   2.1  
gi|190343008 SP110 nuclear body protein isoform b [Homo sapiens]       28   2.1  
gi|190343006 SP110 nuclear body protein isoform c [Homo sapiens]       28   2.1  
gi|88758613 CD93 antigen precursor [Homo sapiens]                      28   2.7  
gi|148596944 C2 calcium-dependent domain containing 3 [Homo sapi...    27   4.6  
gi|5729858 nuclear receptor coactivator 2 [Homo sapiens]               27   6.0  

>gi|7108344 granulysin isoform NKG5 [Homo sapiens]
          Length = 145

 Score =  297 bits (761), Expect = 2e-81
 Identities = 145/145 (100%), Positives = 145/145 (100%)

Query: 1   MATWALLLLAAMLLGNPGLVFSRLSPEYYDLARAHLRDEEKSCPCLAQEGPQGDLLTKTQ 60
           MATWALLLLAAMLLGNPGLVFSRLSPEYYDLARAHLRDEEKSCPCLAQEGPQGDLLTKTQ
Sbjct: 1   MATWALLLLAAMLLGNPGLVFSRLSPEYYDLARAHLRDEEKSCPCLAQEGPQGDLLTKTQ 60

Query: 61  ELGRDYRTCLTIVQKLKKMVDKPTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQ 120
           ELGRDYRTCLTIVQKLKKMVDKPTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQ
Sbjct: 61  ELGRDYRTCLTIVQKLKKMVDKPTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQ 120

Query: 121 GLVAGETAQQICEDLRLCIPSTGPL 145
           GLVAGETAQQICEDLRLCIPSTGPL
Sbjct: 121 GLVAGETAQQICEDLRLCIPSTGPL 145


>gi|157502222 granulysin isoform 519 [Homo sapiens]
          Length = 130

 Score =  265 bits (676), Expect = 1e-71
 Identities = 128/128 (100%), Positives = 128/128 (100%)

Query: 18  GLVFSRLSPEYYDLARAHLRDEEKSCPCLAQEGPQGDLLTKTQELGRDYRTCLTIVQKLK 77
           GLVFSRLSPEYYDLARAHLRDEEKSCPCLAQEGPQGDLLTKTQELGRDYRTCLTIVQKLK
Sbjct: 3   GLVFSRLSPEYYDLARAHLRDEEKSCPCLAQEGPQGDLLTKTQELGRDYRTCLTIVQKLK 62

Query: 78  KMVDKPTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGLVAGETAQQICEDLRL 137
           KMVDKPTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGLVAGETAQQICEDLRL
Sbjct: 63  KMVDKPTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGLVAGETAQQICEDLRL 122

Query: 138 CIPSTGPL 145
           CIPSTGPL
Sbjct: 123 CIPSTGPL 130


>gi|145977198 prosaposin-like protein 1 [Homo sapiens]
          Length = 521

 Score = 33.9 bits (76), Expect = 0.049
 Identities = 20/71 (28%), Positives = 37/71 (52%), Gaps = 2/71 (2%)

Query: 69  CLTIVQKLKK-MVDKPTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGLVAGET 127
           C+ +VQKL   ++   ++  +++A  RVC    +     C   +  Y   + Q LVA  T
Sbjct: 297 CMNVVQKLDHWLMSNSSELMITHALERVCSVMPASITKECIILVDTYSPSLVQ-LVAKIT 355

Query: 128 AQQICEDLRLC 138
            +++C+ +RLC
Sbjct: 356 PEKVCKFIRLC 366


>gi|110224479 prosaposin isoform c preproprotein [Homo sapiens]
          Length = 526

 Score = 30.0 bits (66), Expect = 0.71
 Identities = 15/71 (21%), Positives = 35/71 (49%), Gaps = 1/71 (1%)

Query: 69  CLTIVQKLKKMVDK-PTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGLVAGET 127
           C  +V+++ K++D   T++ + +A  ++C        + C+  +  Y S +   L+   +
Sbjct: 320 CEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVS 379

Query: 128 AQQICEDLRLC 138
            + +C  L LC
Sbjct: 380 PELVCSMLHLC 390


>gi|110224476 prosaposin isoform b preproprotein [Homo sapiens]
          Length = 527

 Score = 30.0 bits (66), Expect = 0.71
 Identities = 15/71 (21%), Positives = 35/71 (49%), Gaps = 1/71 (1%)

Query: 69  CLTIVQKLKKMVDK-PTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGLVAGET 127
           C  +V+++ K++D   T++ + +A  ++C        + C+  +  Y S +   L+   +
Sbjct: 321 CEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVS 380

Query: 128 AQQICEDLRLC 138
            + +C  L LC
Sbjct: 381 PELVCSMLHLC 391


>gi|11386147 prosaposin isoform a preproprotein [Homo sapiens]
          Length = 524

 Score = 30.0 bits (66), Expect = 0.71
 Identities = 15/71 (21%), Positives = 35/71 (49%), Gaps = 1/71 (1%)

Query: 69  CLTIVQKLKKMVDK-PTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGLVAGET 127
           C  +V+++ K++D   T++ + +A  ++C        + C+  +  Y S +   L+   +
Sbjct: 318 CEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVS 377

Query: 128 AQQICEDLRLC 138
            + +C  L LC
Sbjct: 378 PELVCSMLHLC 388


>gi|239754072 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 379

 Score = 28.9 bits (63), Expect = 1.6
 Identities = 23/64 (35%), Positives = 35/64 (54%), Gaps = 4/64 (6%)

Query: 33  RAHLRDEEKSCPCLAQEGPQGDLLTKTQELGRDYRTCLTIVQKLKKMVDKPTQRSVSNAA 92
           RA LR    SC C  +EG + +LL +T+E  R+  + L I+ K+K    +  ++SV    
Sbjct: 305 RAVLRALVLSC-CFPEEGLR-ELLEQTRE--REEGSTLKILSKVKFEACRKEEKSVEKCR 360

Query: 93  TRVC 96
            RVC
Sbjct: 361 YRVC 364


>gi|190343010 SP110 nuclear body protein isoform a [Homo sapiens]
          Length = 689

 Score = 28.5 bits (62), Expect = 2.1
 Identities = 22/80 (27%), Positives = 35/80 (43%), Gaps = 17/80 (21%)

Query: 73  VQKLKKMVDKPTQRS------------VSNAATRVCRTGRSRWR----DVCRNFMRRYQS 116
           +Q+  ++VDK TQR             V  A T+  R  RS+ +    D+C +  RR+Q 
Sbjct: 385 IQEKLQVVDKVTQRKDDSTWNSEVMMRVQKARTKCARKSRSKEKKKEKDICSSSKRRFQK 444

Query: 117 RV-TQGLVAGETAQQICEDL 135
            +  +G    +T    C  L
Sbjct: 445 NIHRRGKPKSDTVDFHCSKL 464


>gi|190343008 SP110 nuclear body protein isoform b [Homo sapiens]
          Length = 549

 Score = 28.5 bits (62), Expect = 2.1
 Identities = 22/80 (27%), Positives = 35/80 (43%), Gaps = 17/80 (21%)

Query: 73  VQKLKKMVDKPTQRS------------VSNAATRVCRTGRSRWR----DVCRNFMRRYQS 116
           +Q+  ++VDK TQR             V  A T+  R  RS+ +    D+C +  RR+Q 
Sbjct: 385 IQEKLQVVDKVTQRKDDSTWNSEVMMRVQKARTKCARKSRSKEKKKEKDICSSSKRRFQK 444

Query: 117 RV-TQGLVAGETAQQICEDL 135
            +  +G    +T    C  L
Sbjct: 445 NIHRRGKPKSDTVDFHCSKL 464


>gi|190343006 SP110 nuclear body protein isoform c [Homo sapiens]
          Length = 713

 Score = 28.5 bits (62), Expect = 2.1
 Identities = 22/80 (27%), Positives = 35/80 (43%), Gaps = 17/80 (21%)

Query: 73  VQKLKKMVDKPTQRS------------VSNAATRVCRTGRSRWR----DVCRNFMRRYQS 116
           +Q+  ++VDK TQR             V  A T+  R  RS+ +    D+C +  RR+Q 
Sbjct: 385 IQEKLQVVDKVTQRKDDSTWNSEVMMRVQKARTKCARKSRSKEKKKEKDICSSSKRRFQK 444

Query: 117 RV-TQGLVAGETAQQICEDL 135
            +  +G    +T    C  L
Sbjct: 445 NIHRRGKPKSDTVDFHCSKL 464


>gi|88758613 CD93 antigen precursor [Homo sapiens]
          Length = 652

 Score = 28.1 bits (61), Expect = 2.7
 Identities = 18/51 (35%), Positives = 23/51 (45%), Gaps = 2/51 (3%)

Query: 96  CRTGRSRWRDVCRNFMRRYQSRVTQGLV-AGETAQQICEDLRLCIPSTGPL 145
           C  GRS     C N    +     +G V AGE   Q C+D+  C+   GPL
Sbjct: 389 CALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQ-CQDVDECVGPGGPL 438


>gi|148596944 C2 calcium-dependent domain containing 3 [Homo
           sapiens]
          Length = 1963

 Score = 27.3 bits (59), Expect = 4.6
 Identities = 22/92 (23%), Positives = 35/92 (38%), Gaps = 12/92 (13%)

Query: 22  SRLSPEYYDLARAHLRDEEKSCPCLAQEGPQGDLLTKTQELGRDYRTCLTI--------V 73
           S   P+   +A++H      SC   +   P  DLL+   E G   R  + I         
Sbjct: 287 SEFQPQIRTVAKSH----SDSCILSSNNLPTKDLLSALLEQGNKLRNAMVISAMKSSPET 342

Query: 74  QKLKKMVDKPTQRSVSNAATRVCRTGRSRWRD 105
             L   V  P       A+T++    R+R++D
Sbjct: 343 SMLLDQVHPPINEDSLRASTQIRAFSRNRFKD 374


>gi|5729858 nuclear receptor coactivator 2 [Homo sapiens]
          Length = 1464

 Score = 26.9 bits (58), Expect = 6.0
 Identities = 22/105 (20%), Positives = 41/105 (39%), Gaps = 21/105 (20%)

Query: 27  EYYDLARAHLRDEEKSCPCLAQEGPQGDLLTKTQELGRDYRTCLTIVQKLKKMVDKPTQR 86
           E +D   AH + E   C  ++Q           +E G D ++CL  V +   M ++P   
Sbjct: 213 EGHDNQEAHQKYETMQCFAVSQP-------KSIKEEGEDLQSCLICVARRVPMKERPVLP 265

Query: 87  SVSNAATRVCRTG--------------RSRWRDVCRNFMRRYQSR 117
           S  +  TR    G              +  W D+ R  ++++ ++
Sbjct: 266 SSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLVRRCIQKFHAQ 310


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.135    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,816,555
Number of Sequences: 37866
Number of extensions: 227670
Number of successful extensions: 502
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 500
Number of HSP's gapped (non-prelim): 13
length of query: 145
length of database: 18,247,518
effective HSP length: 92
effective length of query: 53
effective length of database: 14,763,846
effective search space: 782483838
effective search space used: 782483838
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 57 (26.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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