Guide to the Human Genome
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Search of human proteins with 13775228

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13775228 deoxyhypusine hydroxylase/monooxygenase [Homo
sapiens]
         (302 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|223633884 deoxyhypusine hydroxylase/monooxygenase [Homo sapiens]   603   e-173
gi|13775228 deoxyhypusine hydroxylase/monooxygenase [Homo sapiens]    603   e-173
gi|189409124 armadillo repeat containing 3 [Homo sapiens]              34   0.18 
gi|26051240 tumor necrosis factor, alpha-induced protein 2 [Homo...    33   0.31 
gi|239746344 PREDICTED: hypothetical protein XP_002343734 [Homo ...    31   1.2  
gi|62739181 rhotekin isoform c [Homo sapiens]                          31   1.5  
gi|62739179 rhotekin isoform a [Homo sapiens]                          31   1.5  
gi|19526471 rhotekin isoform b [Homo sapiens]                          31   1.5  
gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens]            30   2.6  
gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens]           30   3.4  
gi|194097341 period 1 [Homo sapiens]                                   29   4.5  
gi|90903231 huntingtin [Homo sapiens]                                  28   7.6  
gi|87080813 LON peptidase N-terminal domain and ring finger 1 [H...    28   7.6  
gi|239756197 PREDICTED: hypothetical protein [Homo sapiens]            28   10.0 

>gi|223633884 deoxyhypusine hydroxylase/monooxygenase [Homo sapiens]
          Length = 302

 Score =  603 bits (1556), Expect = e-173
 Identities = 302/302 (100%), Positives = 302/302 (100%)

Query: 1   MVTEQEVDAIGQTLVDPKQPLQARFRALFTLRGLGGPGAIAWISQAFDDDSALLKHELAY 60
           MVTEQEVDAIGQTLVDPKQPLQARFRALFTLRGLGGPGAIAWISQAFDDDSALLKHELAY
Sbjct: 1   MVTEQEVDAIGQTLVDPKQPLQARFRALFTLRGLGGPGAIAWISQAFDDDSALLKHELAY 60

Query: 61  CLGQMQDARAIPMLVDVLQDTRQEPMVRHEAGEALGAIGDPEVLEILKQYSSDPVIEVAE 120
           CLGQMQDARAIPMLVDVLQDTRQEPMVRHEAGEALGAIGDPEVLEILKQYSSDPVIEVAE
Sbjct: 61  CLGQMQDARAIPMLVDVLQDTRQEPMVRHEAGEALGAIGDPEVLEILKQYSSDPVIEVAE 120

Query: 121 TCQLAVRRLEWLQQHGGEPAAGPYLSVDPAPPAEERDVGRLREALLDESRPLFERYRAMF 180
           TCQLAVRRLEWLQQHGGEPAAGPYLSVDPAPPAEERDVGRLREALLDESRPLFERYRAMF
Sbjct: 121 TCQLAVRRLEWLQQHGGEPAAGPYLSVDPAPPAEERDVGRLREALLDESRPLFERYRAMF 180

Query: 181 ALRNAGGEEAALALAEGLHCGSALFRHEVGYVLGQLQHEAAVPQLAAALARCTENPMVRH 240
           ALRNAGGEEAALALAEGLHCGSALFRHEVGYVLGQLQHEAAVPQLAAALARCTENPMVRH
Sbjct: 181 ALRNAGGEEAALALAEGLHCGSALFRHEVGYVLGQLQHEAAVPQLAAALARCTENPMVRH 240

Query: 241 ECAEALGAIARPACLAALQAHADDPERVVRESCEVALDMYEHETGRAFQYADGLEQLRGA 300
           ECAEALGAIARPACLAALQAHADDPERVVRESCEVALDMYEHETGRAFQYADGLEQLRGA
Sbjct: 241 ECAEALGAIARPACLAALQAHADDPERVVRESCEVALDMYEHETGRAFQYADGLEQLRGA 300

Query: 301 PS 302
           PS
Sbjct: 301 PS 302


>gi|13775228 deoxyhypusine hydroxylase/monooxygenase [Homo sapiens]
          Length = 302

 Score =  603 bits (1556), Expect = e-173
 Identities = 302/302 (100%), Positives = 302/302 (100%)

Query: 1   MVTEQEVDAIGQTLVDPKQPLQARFRALFTLRGLGGPGAIAWISQAFDDDSALLKHELAY 60
           MVTEQEVDAIGQTLVDPKQPLQARFRALFTLRGLGGPGAIAWISQAFDDDSALLKHELAY
Sbjct: 1   MVTEQEVDAIGQTLVDPKQPLQARFRALFTLRGLGGPGAIAWISQAFDDDSALLKHELAY 60

Query: 61  CLGQMQDARAIPMLVDVLQDTRQEPMVRHEAGEALGAIGDPEVLEILKQYSSDPVIEVAE 120
           CLGQMQDARAIPMLVDVLQDTRQEPMVRHEAGEALGAIGDPEVLEILKQYSSDPVIEVAE
Sbjct: 61  CLGQMQDARAIPMLVDVLQDTRQEPMVRHEAGEALGAIGDPEVLEILKQYSSDPVIEVAE 120

Query: 121 TCQLAVRRLEWLQQHGGEPAAGPYLSVDPAPPAEERDVGRLREALLDESRPLFERYRAMF 180
           TCQLAVRRLEWLQQHGGEPAAGPYLSVDPAPPAEERDVGRLREALLDESRPLFERYRAMF
Sbjct: 121 TCQLAVRRLEWLQQHGGEPAAGPYLSVDPAPPAEERDVGRLREALLDESRPLFERYRAMF 180

Query: 181 ALRNAGGEEAALALAEGLHCGSALFRHEVGYVLGQLQHEAAVPQLAAALARCTENPMVRH 240
           ALRNAGGEEAALALAEGLHCGSALFRHEVGYVLGQLQHEAAVPQLAAALARCTENPMVRH
Sbjct: 181 ALRNAGGEEAALALAEGLHCGSALFRHEVGYVLGQLQHEAAVPQLAAALARCTENPMVRH 240

Query: 241 ECAEALGAIARPACLAALQAHADDPERVVRESCEVALDMYEHETGRAFQYADGLEQLRGA 300
           ECAEALGAIARPACLAALQAHADDPERVVRESCEVALDMYEHETGRAFQYADGLEQLRGA
Sbjct: 241 ECAEALGAIARPACLAALQAHADDPERVVRESCEVALDMYEHETGRAFQYADGLEQLRGA 300

Query: 301 PS 302
           PS
Sbjct: 301 PS 302


>gi|189409124 armadillo repeat containing 3 [Homo sapiens]
          Length = 872

 Score = 33.9 bits (76), Expect = 0.18
 Identities = 58/235 (24%), Positives = 98/235 (41%), Gaps = 45/235 (19%)

Query: 61  CLGQMQDARAIPMLVDVLQDTRQEPMVRHEAGEALGAI-GDPEVLEILKQYSS-DPVIEV 118
           C  ++Q+  AIP ++D+L+   + P+++  A + LG I  D E   +L+     D +I++
Sbjct: 183 CRAKLQELNAIPPILDLLKS--EYPVIQLLALKTLGVIANDKESRTMLRDNQGLDHLIKI 240

Query: 119 AETCQLAVRRLEWL----------------QQHGGEPAAGPYLSVDPAPPAEERDVGRLR 162
            ET +L    +E L                QQ GG      +      P  ++     + 
Sbjct: 241 LETKELNDLHIEALAVIANCLEDMDTMVQIQQTGGLKKLLSFAENSTIPDIQKNAAKAIT 300

Query: 163 EALLD-ESRPLF---ERYRAMFALRNAGGEEAALALAEGL-----HCGSALFRHEVGYVL 213
           +A  D E+R LF   E  + + AL  +  +   +A ++ +     + GS  F +  G   
Sbjct: 301 KAAYDPENRKLFHEQEVEKCLVALLGSENDGTKIAASQAISAMCENSGSKDFFNNQG--- 357

Query: 214 GQLQHEAAVPQLAAALARCTENPMVRHECAEALGAI--ARPA-CLAALQAHADDP 265
                   +PQL   L   ++N  VR   A AL  +    PA   AA +A   DP
Sbjct: 358 --------IPQLIQLLK--SDNEEVREAAALALANLTTCNPANANAAAEADGIDP 402


>gi|26051240 tumor necrosis factor, alpha-induced protein 2 [Homo
           sapiens]
          Length = 654

 Score = 33.1 bits (74), Expect = 0.31
 Identities = 35/112 (31%), Positives = 45/112 (40%), Gaps = 7/112 (6%)

Query: 138 EPAAGPYLSVDPAPPAEERDVGRLREALLDESRPLFERYRAMFALRNAGG--EEAALALA 195
           E AAG    +D  PP  E     L    L+ +RPL    R + A   AGG  EE  +   
Sbjct: 63  EDAAGSRQGLDGPPPTVEELKAALERGQLEAARPLLALERELAAAAAAGGVSEEELVRRQ 122

Query: 196 EGLHCGSALFRHEVGYVLGQLQH--EAAVPQLAAALARCTENPMVRHECAEA 245
             +     L R +   VLG L+   EA   +L  ALA   E      + A A
Sbjct: 123 SKVEALYELLRDQ---VLGVLRRPLEAPPERLRQALAVVAEQEREDRQAAAA 171


>gi|239746344 PREDICTED: hypothetical protein XP_002343734 [Homo
           sapiens]
          Length = 194

 Score = 31.2 bits (69), Expect = 1.2
 Identities = 43/145 (29%), Positives = 58/145 (40%), Gaps = 20/145 (13%)

Query: 90  EAGEALGAIGDPEVL--EILKQYSSDPVIEVAETCQLAVRRLEWLQQHGGEPAAGPYLSV 147
           E G AL    + E L   I+      PV+      Q+   RL  L       A  P    
Sbjct: 4   EEGHALAVFEEVEALGAPIVHAQPHGPVVGSERRAQVPSERLHLLAVCRLRQAPAPRR-- 61

Query: 148 DPAPPAEER---DVGRLREALLDESRPLFERYRAMF---ALRNAGGEEAALALA------ 195
             AP    R   +V R +EAL+ +++PL   Y  +F   A R    + A LAL       
Sbjct: 62  --APRLRRRLSFEVAREQEALVAQAQPLQAAYSLIFFHPARRGLTLQAAVLALGATLRLL 119

Query: 196 EGLH--CGSALFRHEVGYVLGQLQH 218
           +GLH   G A    ++   LGQL H
Sbjct: 120 QGLHGIAGVACRVPQLPQPLGQLDH 144


>gi|62739181 rhotekin isoform c [Homo sapiens]
          Length = 513

 Score = 30.8 bits (68), Expect = 1.5
 Identities = 24/77 (31%), Positives = 32/77 (41%), Gaps = 19/77 (24%)

Query: 53  LLKHELAYCLGQMQDARAIPMLVDVLQDTRQEPMV--------RHEAGEALGAIGDPEVL 104
           +LK    +C  Q +DA           DT +EP++        R  AGE   A+G P  L
Sbjct: 283 VLKGTNLFCYRQPEDA-----------DTGEEPLLTIAVNKETRVRAGELDQALGRPFTL 331

Query: 105 EILKQYSSDPVIEVAET 121
            I  QY  D V    +T
Sbjct: 332 SISNQYGDDEVTHTLQT 348


>gi|62739179 rhotekin isoform a [Homo sapiens]
          Length = 563

 Score = 30.8 bits (68), Expect = 1.5
 Identities = 24/77 (31%), Positives = 32/77 (41%), Gaps = 19/77 (24%)

Query: 53  LLKHELAYCLGQMQDARAIPMLVDVLQDTRQEPMV--------RHEAGEALGAIGDPEVL 104
           +LK    +C  Q +DA           DT +EP++        R  AGE   A+G P  L
Sbjct: 333 VLKGTNLFCYRQPEDA-----------DTGEEPLLTIAVNKETRVRAGELDQALGRPFTL 381

Query: 105 EILKQYSSDPVIEVAET 121
            I  QY  D V    +T
Sbjct: 382 SISNQYGDDEVTHTLQT 398


>gi|19526471 rhotekin isoform b [Homo sapiens]
          Length = 550

 Score = 30.8 bits (68), Expect = 1.5
 Identities = 24/77 (31%), Positives = 32/77 (41%), Gaps = 19/77 (24%)

Query: 53  LLKHELAYCLGQMQDARAIPMLVDVLQDTRQEPMV--------RHEAGEALGAIGDPEVL 104
           +LK    +C  Q +DA           DT +EP++        R  AGE   A+G P  L
Sbjct: 320 VLKGTNLFCYRQPEDA-----------DTGEEPLLTIAVNKETRVRAGELDQALGRPFTL 368

Query: 105 EILKQYSSDPVIEVAET 121
            I  QY  D V    +T
Sbjct: 369 SISNQYGDDEVTHTLQT 385


>gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens]
          Length = 789

 Score = 30.0 bits (66), Expect = 2.6
 Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 7/51 (13%)

Query: 143 PYLSVDPAPPAEERDVGRLREALLDESRPLFERYRAMFALRNAGGEEAALA 193
           PY SVDP       + G ++ AL D SR   E+Y+ +   ++ GG+   L+
Sbjct: 206 PYFSVDP-------ESGIIKTALPDMSRENREQYQVVIQAKDMGGQMGGLS 249


>gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens]
          Length = 794

 Score = 29.6 bits (65), Expect = 3.4
 Identities = 16/51 (31%), Positives = 26/51 (50%), Gaps = 7/51 (13%)

Query: 143 PYLSVDPAPPAEERDVGRLREALLDESRPLFERYRAMFALRNAGGEEAALA 193
           PY S+DP         G +R AL +  R + E+Y+ +   ++ GG+   LA
Sbjct: 207 PYFSIDPK-------TGVIRTALPNMDREVKEQYQVLIQAKDMGGQLGGLA 250


>gi|194097341 period 1 [Homo sapiens]
          Length = 1290

 Score = 29.3 bits (64), Expect = 4.5
 Identities = 29/97 (29%), Positives = 39/97 (40%), Gaps = 9/97 (9%)

Query: 123  QLAVRRLEWLQQ-HGGEPAAGPYLSVDPAPPAEE--RDVGRLREALLDESRPLFERYRAM 179
            QL + +LE L +  G   A GP  S  P PP+ E      RL E     ++        +
Sbjct: 983  QLNLLQLEELPRAEGAAVAGGPGSSAGPPPPSAEAAEPEARLAEVTESSNQDALSGSSDL 1042

Query: 180  FAL------RNAGGEEAALALAEGLHCGSALFRHEVG 210
              L      R+  G  A+ +L  GL  GS    HE G
Sbjct: 1043 LELLLQEDSRSGTGSAASGSLGSGLGSGSGSGSHEGG 1079


>gi|90903231 huntingtin [Homo sapiens]
          Length = 3144

 Score = 28.5 bits (62), Expect = 7.6
 Identities = 28/92 (30%), Positives = 37/92 (40%), Gaps = 7/92 (7%)

Query: 193 ALAEGLHCGSALFRHEVGYVLGQLQHEAAVPQLAAALARCTENPMVRHECAEALGAIARP 252
           A AE LH G+    H  G +  +LQ       +   L    E+P VRH  A +L  +   
Sbjct: 887 AKAENLHRGA---HHYTGLL--KLQERVLNNVVIHLLG--DEDPRVRHVAAASLIRLVPK 939

Query: 253 ACLAALQAHADDPERVVRESCEVALDMYEHET 284
                 Q  AD    V R+   V L +  HET
Sbjct: 940 LFYKCDQGQADPVVAVARDQSSVYLKLLMHET 971


>gi|87080813 LON peptidase N-terminal domain and ring finger 1 [Homo
           sapiens]
          Length = 773

 Score = 28.5 bits (62), Expect = 7.6
 Identities = 15/47 (31%), Positives = 27/47 (57%)

Query: 88  RHEAGEALGAIGDPEVLEILKQYSSDPVIEVAETCQLAVRRLEWLQQ 134
           R ++ +++ +   P   + LK+ SS+PV+ V E   L  R+L  L+Q
Sbjct: 389 RAQSAQSINSTEMPAREDCLKRVSSEPVLSVQEKGVLLKRKLSLLEQ 435


>gi|239756197 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 331

 Score = 28.1 bits (61), Expect = 10.0
 Identities = 23/79 (29%), Positives = 33/79 (41%), Gaps = 1/79 (1%)

Query: 196 EGLHCGSALFRHEVGY-VLGQLQHEAAVPQLAAALARCTENPMVRHECAEALGAIARPAC 254
           + LH G   +R  VG  ++ +      + +  AAL    + P+V  E  EA+G   RP  
Sbjct: 165 QNLHPGPREYRTPVGTGIIPRPGGTETLREACAALGEGRQPPLVSAESWEAVGFERRPGE 224

Query: 255 LAALQAHADDPERVVRESC 273
           L A     D   R  R  C
Sbjct: 225 LCAEPGGPDLLPRAFRSRC 243


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,990,241
Number of Sequences: 37866
Number of extensions: 521318
Number of successful extensions: 1414
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1401
Number of HSP's gapped (non-prelim): 18
length of query: 302
length of database: 18,247,518
effective HSP length: 102
effective length of query: 200
effective length of database: 14,385,186
effective search space: 2877037200
effective search space used: 2877037200
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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