Search of human proteins with 6912516

Search of human proteins with 6912516

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|6912516 methionine sulfoxide reductase A isoform a [Homo
sapiens]
         (235 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|6912516 methionine sulfoxide reductase A isoform a [Homo sapi...   494   e-140
gi|208609995 methionine sulfoxide reductase A isoform c [Homo sa...   402   e-112
gi|208609993 methionine sulfoxide reductase A isoform b [Homo sa...   386   e-108
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]             33   0.28 
gi|145701005 hypothetical protein LOC375759 [Homo sapiens]             32   0.62 
gi|154937380 hypothetical protein LOC642475 [Homo sapiens]             30   1.4  
gi|148613886 regulatory factor X domain containing 2 [Homo sapiens]    30   2.3  
gi|45827809 mitogen-activated protein kinase kinase kinase 6 [Ho...    29   3.1  
gi|4506885 semenogelin II precursor [Homo sapiens]                     29   3.1  
gi|28557777 immunoglobulin-like domain containing receptor 1 [Ho...    29   4.0  
gi|4759208 TAO kinase 2 isoform 1 [Homo sapiens]                       28   6.8  

>gi|6912516 methionine sulfoxide reductase A isoform a [Homo
           sapiens]
          Length = 235

 Score =  494 bits (1272), Expect = e-140
 Identities = 235/235 (100%), Positives = 235/235 (100%)

Query: 1   MLSATRRACQLLLLHSLFPVPRMGNSASNIVSPQEALPGRKEQTPVAAKHHVNGNRTVEP 60
           MLSATRRACQLLLLHSLFPVPRMGNSASNIVSPQEALPGRKEQTPVAAKHHVNGNRTVEP
Sbjct: 1   MLSATRRACQLLLLHSLFPVPRMGNSASNIVSPQEALPGRKEQTPVAAKHHVNGNRTVEP 60

Query: 61  FPEGTQMAVFGMGCFWGAERKFWVLKGVYSTQVGFAGGYTSNPTYKEVCSEKTGHAEVVR 120
           FPEGTQMAVFGMGCFWGAERKFWVLKGVYSTQVGFAGGYTSNPTYKEVCSEKTGHAEVVR
Sbjct: 61  FPEGTQMAVFGMGCFWGAERKFWVLKGVYSTQVGFAGGYTSNPTYKEVCSEKTGHAEVVR 120

Query: 121 VVYQPEHMSFEELLKVFWENHDPTQGMRQGNDHGTQYRSAIYPTSAKQMEAALSSKENYQ 180
           VVYQPEHMSFEELLKVFWENHDPTQGMRQGNDHGTQYRSAIYPTSAKQMEAALSSKENYQ
Sbjct: 121 VVYQPEHMSFEELLKVFWENHDPTQGMRQGNDHGTQYRSAIYPTSAKQMEAALSSKENYQ 180

Query: 181 KVLSEHGFGPITTDIREGQTFYYAEDYHQQYLSKNPNGYCGLGGTGVSCPVGIKK 235
           KVLSEHGFGPITTDIREGQTFYYAEDYHQQYLSKNPNGYCGLGGTGVSCPVGIKK
Sbjct: 181 KVLSEHGFGPITTDIREGQTFYYAEDYHQQYLSKNPNGYCGLGGTGVSCPVGIKK 235


>gi|208609995 methionine sulfoxide reductase A isoform c [Homo
           sapiens]
          Length = 192

 Score =  402 bits (1032), Expect = e-112
 Identities = 187/187 (100%), Positives = 187/187 (100%)

Query: 49  KHHVNGNRTVEPFPEGTQMAVFGMGCFWGAERKFWVLKGVYSTQVGFAGGYTSNPTYKEV 108
           KHHVNGNRTVEPFPEGTQMAVFGMGCFWGAERKFWVLKGVYSTQVGFAGGYTSNPTYKEV
Sbjct: 6   KHHVNGNRTVEPFPEGTQMAVFGMGCFWGAERKFWVLKGVYSTQVGFAGGYTSNPTYKEV 65

Query: 109 CSEKTGHAEVVRVVYQPEHMSFEELLKVFWENHDPTQGMRQGNDHGTQYRSAIYPTSAKQ 168
           CSEKTGHAEVVRVVYQPEHMSFEELLKVFWENHDPTQGMRQGNDHGTQYRSAIYPTSAKQ
Sbjct: 66  CSEKTGHAEVVRVVYQPEHMSFEELLKVFWENHDPTQGMRQGNDHGTQYRSAIYPTSAKQ 125

Query: 169 MEAALSSKENYQKVLSEHGFGPITTDIREGQTFYYAEDYHQQYLSKNPNGYCGLGGTGVS 228
           MEAALSSKENYQKVLSEHGFGPITTDIREGQTFYYAEDYHQQYLSKNPNGYCGLGGTGVS
Sbjct: 126 MEAALSSKENYQKVLSEHGFGPITTDIREGQTFYYAEDYHQQYLSKNPNGYCGLGGTGVS 185

Query: 229 CPVGIKK 235
           CPVGIKK
Sbjct: 186 CPVGIKK 192


>gi|208609993 methionine sulfoxide reductase A isoform b [Homo
           sapiens]
          Length = 195

 Score =  386 bits (992), Expect = e-108
 Identities = 195/235 (82%), Positives = 195/235 (82%), Gaps = 40/235 (17%)

Query: 1   MLSATRRACQLLLLHSLFPVPRMGNSASNIVSPQEALPGRKEQTPVAAKHHVNGNRTVEP 60
           MLSATRRACQLLLLHSLFPVPRMGNSASNIVSPQEALPGRKEQTPVAAKHHVNGNRTVEP
Sbjct: 1   MLSATRRACQLLLLHSLFPVPRMGNSASNIVSPQEALPGRKEQTPVAAKHHVNGNRTVEP 60

Query: 61  FPEGTQMAVFGMGCFWGAERKFWVLKGVYSTQVGFAGGYTSNPTYKEVCSEKTGHAEVVR 120
           FPEGTQMAVF                                        EKTGHAEVVR
Sbjct: 61  FPEGTQMAVF----------------------------------------EKTGHAEVVR 80

Query: 121 VVYQPEHMSFEELLKVFWENHDPTQGMRQGNDHGTQYRSAIYPTSAKQMEAALSSKENYQ 180
           VVYQPEHMSFEELLKVFWENHDPTQGMRQGNDHGTQYRSAIYPTSAKQMEAALSSKENYQ
Sbjct: 81  VVYQPEHMSFEELLKVFWENHDPTQGMRQGNDHGTQYRSAIYPTSAKQMEAALSSKENYQ 140

Query: 181 KVLSEHGFGPITTDIREGQTFYYAEDYHQQYLSKNPNGYCGLGGTGVSCPVGIKK 235
           KVLSEHGFGPITTDIREGQTFYYAEDYHQQYLSKNPNGYCGLGGTGVSCPVGIKK
Sbjct: 141 KVLSEHGFGPITTDIREGQTFYYAEDYHQQYLSKNPNGYCGLGGTGVSCPVGIKK 195


>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
          Length = 4391

 Score = 32.7 bits (73), Expect = 0.28
 Identities = 34/115 (29%), Positives = 49/115 (42%), Gaps = 19/115 (16%)

Query: 52   VNGNRTVEPFPEGTQMAVFGMGCFWGAERKFWVLKGVY-STQVGFAGG-------YTSNP 103
            + G  TVEP PEG Q++ FG     G E  +W L   Y   +V   GG       YT+ P
Sbjct: 1367 LTGEFTVEPVPEGAQLS-FGNFAQLGHESFYWQLPETYQGDKVAAYGGKLRYTLSYTAGP 1425

Query: 104  TYKEVCS---EKTGHAEVVRVVYQ-----PEHMSFEELLK-VFWENHDPTQGMRQ 149
                +     + TG+  ++ V  Q     PE  S+E + +  FW   D     R+
Sbjct: 1426 QGSPLSDPDVQITGN-NIMLVASQPALQGPERRSYEIMFREEFWRRPDGQPATRE 1479


>gi|145701005 hypothetical protein LOC375759 [Homo sapiens]
          Length = 431

 Score = 31.6 bits (70), Expect = 0.62
 Identities = 18/44 (40%), Positives = 27/44 (61%), Gaps = 1/44 (2%)

Query: 1   MLSATRRACQLL-LLHSLFPVPRMGNSASNIVSPQEALPGRKEQ 43
           +L+ATRRA +   LL SL P P +   AS   +P++  PG +E+
Sbjct: 83  LLTATRRAVRKRGLLRSLLPPPLLSAGASRESAPRQPGPGERER 126


>gi|154937380 hypothetical protein LOC642475 [Homo sapiens]
          Length = 719

 Score = 30.4 bits (67), Expect = 1.4
 Identities = 14/35 (40%), Positives = 18/35 (51%)

Query: 30 IVSPQEALPGRKEQTPVAAKHHVNGNRTVEPFPEG 64
          + +P EA PGR    P A     + N  +EP PEG
Sbjct: 61 LTAPSEAEPGRGATVPEAGSEPCSLNSALEPAPEG 95


>gi|148613886 regulatory factor X domain containing 2 [Homo sapiens]
          Length = 1460

 Score = 29.6 bits (65), Expect = 2.3
 Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 7/91 (7%)

Query: 107 EVCSEKTGHAEVVRVVYQPEHMSFEELLKVFWENHDPTQGMRQGNDHGTQYRSAIYPTSA 166
           E  S      + + V+  PEH    +L K  WE     +GM Q + +  Q  S I  +S 
Sbjct: 790 EFISASCEQQQDISVMTIPEHSDINDLEKSVWE----LEGMPQ-DTYSQQLHSQIQESSL 844

Query: 167 KQMEAALSSKENYQKVLSEHGFGPITTDIRE 197
            Q++A  S +   Q  L E  F P  +   E
Sbjct: 845 NQIQAHSSDQLPLQSELKE--FEPSVSQTNE 873


>gi|45827809 mitogen-activated protein kinase kinase kinase 6 [Homo
           sapiens]
          Length = 1288

 Score = 29.3 bits (64), Expect = 3.1
 Identities = 14/50 (28%), Positives = 25/50 (50%)

Query: 1   MLSATRRACQLLLLHSLFPVPRMGNSASNIVSPQEALPGRKEQTPVAAKH 50
           M S+     Q  LL +  P PR+  SA  ++      PG++ ++P + +H
Sbjct: 871 MPSSLSAEAQAFLLRTFEPDPRLRASAQTLLGDPFLQPGKRSRSPSSPRH 920


>gi|4506885 semenogelin II precursor [Homo sapiens]
          Length = 582

 Score = 29.3 bits (64), Expect = 3.1
 Identities = 18/92 (19%), Positives = 39/92 (42%), Gaps = 11/92 (11%)

Query: 105 YKEVCSEKTGHAEVVRVVYQPEHM-----------SFEELLKVFWENHDPTQGMRQGNDH 153
           Y+ V   +  H+  ++    P H            + ++ L V+ +N   T+ + Q  +H
Sbjct: 220 YQNVVDVREEHSSKLQTSLHPAHQDRLQHGPKDIFTTQDELLVYNKNQHQTKNLSQDQEH 279

Query: 154 GTQYRSAIYPTSAKQMEAALSSKENYQKVLSE 185
           G +     YP+S  +       +++ QK +S+
Sbjct: 280 GRKAHKISYPSSRTEERQLHHGEKSVQKDVSK 311


>gi|28557777 immunoglobulin-like domain containing receptor 1 [Homo
           sapiens]
          Length = 502

 Score = 28.9 bits (63), Expect = 4.0
 Identities = 14/50 (28%), Positives = 25/50 (50%), Gaps = 3/50 (6%)

Query: 173 LSSKENYQKVLSEHGFGPITT---DIREGQTFYYAEDYHQQYLSKNPNGY 219
           LSS       L +    PI +   D+REG++ ++  D+HQ+   + P  +
Sbjct: 295 LSSSRRTSDSLHQQWLTPIPSRPWDLREGRSHHHYPDFHQELQDRGPKSW 344


>gi|4759208 TAO kinase 2 isoform 1 [Homo sapiens]
          Length = 1049

 Score = 28.1 bits (61), Expect = 6.8
 Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 4/57 (7%)

Query: 3    SATRRACQLLLL-HSLFPVPRM---GNSASNIVSPQEALPGRKEQTPVAAKHHVNGN 55
            S T R   LLLL +S  P+ R    G+ + N+  P  A+PG   ++   A H +NG+
Sbjct: 988  SGTPRGGALLLLRNSPQPLRRAASGGSGSENVGPPAAAVPGPLSRSTSVASHILNGS 1044


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,789,356
Number of Sequences: 37866
Number of extensions: 438592
Number of successful extensions: 968
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 962
Number of HSP's gapped (non-prelim): 12
length of query: 235
length of database: 18,247,518
effective HSP length: 99
effective length of query: 136
effective length of database: 14,498,784
effective search space: 1971834624
effective search space used: 1971834624
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.