Guide to the Human Genome
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Search of human proteins with 69122971

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|69122971 1-acylglycerol-3-phosphate O-acyltransferase 2
isoform b [Homo sapiens]
         (246 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|69122971 1-acylglycerol-3-phosphate O-acyltransferase 2 isofo...   487   e-138
gi|6041665 1-acylglycerol-3-phosphate O-acyltransferase 2 isofor...   470   e-133
gi|5453718 1-acylglycerol-3-phosphate O-acyltransferase 1 [Homo ...   181   7e-46
gi|15100175 1-acylglycerol-3-phosphate O-acyltransferase 1 [Homo...   181   7e-46
gi|44771201 integrator complex subunit 5 [Homo sapiens]                28   5.6  
gi|215598824 ankyrin repeat and SOCS box-containing 10 isoform 2...    28   7.3  
gi|24308245 RecQ-mediated genome instability protein 2 [Homo sap...    28   9.5  
gi|84662753 G protein-coupled receptor 149 [Homo sapiens]              28   9.5  

>gi|69122971 1-acylglycerol-3-phosphate O-acyltransferase 2 isoform
           b [Homo sapiens]
          Length = 246

 Score =  487 bits (1253), Expect = e-138
 Identities = 246/246 (100%), Positives = 246/246 (100%)

Query: 1   MELWPCLAAALLLLLLLVQLSRAAEFYAKVALYCALCFTVSAVASLVCLLRHGGRTVENM 60
           MELWPCLAAALLLLLLLVQLSRAAEFYAKVALYCALCFTVSAVASLVCLLRHGGRTVENM
Sbjct: 1   MELWPCLAAALLLLLLLVQLSRAAEFYAKVALYCALCFTVSAVASLVCLLRHGGRTVENM 60

Query: 61  SIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLPERCVQIAK 120
           SIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLPERCVQIAK
Sbjct: 61  SIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLPERCVQIAK 120

Query: 121 RELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENVPIVPVVYSSFSSFYN 180
           RELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENVPIVPVVYSSFSSFYN
Sbjct: 121 RELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENVPIVPVVYSSFSSFYN 180

Query: 181 TKKKFFTSGTVTVQVLEAIPTSGLTAADVPALVDTCHRAMRTTFLHISKTPQENGATAGS 240
           TKKKFFTSGTVTVQVLEAIPTSGLTAADVPALVDTCHRAMRTTFLHISKTPQENGATAGS
Sbjct: 181 TKKKFFTSGTVTVQVLEAIPTSGLTAADVPALVDTCHRAMRTTFLHISKTPQENGATAGS 240

Query: 241 GVQPAQ 246
           GVQPAQ
Sbjct: 241 GVQPAQ 246


>gi|6041665 1-acylglycerol-3-phosphate O-acyltransferase 2 isoform a
           [Homo sapiens]
          Length = 278

 Score =  470 bits (1210), Expect = e-133
 Identities = 246/278 (88%), Positives = 246/278 (88%), Gaps = 32/278 (11%)

Query: 1   MELWPCLAAALLLLLLLVQLSRAAEFYAKVALYCALCFTVSAVASLVCLLRHGGRTVENM 60
           MELWPCLAAALLLLLLLVQLSRAAEFYAKVALYCALCFTVSAVASLVCLLRHGGRTVENM
Sbjct: 1   MELWPCLAAALLLLLLLVQLSRAAEFYAKVALYCALCFTVSAVASLVCLLRHGGRTVENM 60

Query: 61  SIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLPERCVQIAK 120
           SIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLPERCVQIAK
Sbjct: 61  SIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLPERCVQIAK 120

Query: 121 RELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVREN---------------- 164
           RELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVREN                
Sbjct: 121 RELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENLKVWIYPEGTRNDNGD 180

Query: 165 ----------------VPIVPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIPTSGLTAAD 208
                           VPIVPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIPTSGLTAAD
Sbjct: 181 LLPFKKGAFYLAVQAQVPIVPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIPTSGLTAAD 240

Query: 209 VPALVDTCHRAMRTTFLHISKTPQENGATAGSGVQPAQ 246
           VPALVDTCHRAMRTTFLHISKTPQENGATAGSGVQPAQ
Sbjct: 241 VPALVDTCHRAMRTTFLHISKTPQENGATAGSGVQPAQ 278


>gi|5453718 1-acylglycerol-3-phosphate O-acyltransferase 1 [Homo
           sapiens]
          Length = 283

 Score =  181 bits (458), Expect = 7e-46
 Identities = 109/275 (39%), Positives = 150/275 (54%), Gaps = 42/275 (15%)

Query: 1   MELWPCLAAALLLLLLLVQL--------SRAAEFYAKVALYCALCFTVSAVASLVCLLRH 52
           M+LWP     LLLL LL+          S +A+++ K+A Y      ++ +A  VC +R 
Sbjct: 1   MDLWPGAWMLLLLLFLLLLFLLPTLWFCSPSAKYFFKMAFYNGWILFLAVLAIPVCAVR- 59

Query: 53  GGRTVENMSIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLP 112
            GR VENM I+   +   KY YG+R EVR       ++P V+VSNHQS LD++G+MEVLP
Sbjct: 60  -GRNVENMKILRLMLLHIKYLYGIRVEVRGAHHFPPSQPYVVVSNHQSSLDLLGMMEVLP 118

Query: 113 ERCVQIAKRELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERM------------ 160
            RCV IAKRELL+ G  GL  +L GV FI+R+R+  A++VM+++ + +            
Sbjct: 119 GRCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVMSEVAQTLLTQDVRVWVFPE 178

Query: 161 --------------------VRENVPIVPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIP 200
                               V+  VPIVP+V SS+  FY  K++ FTSG   V+VL  +P
Sbjct: 179 GTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMSSYQDFYCKKERRFTSGQCQVRVLPPVP 238

Query: 201 TSGLTAADVPALVDTCHRAMRTTFLHISKTPQENG 235
           T GLT  DVPAL D    +M T F  IS   +  G
Sbjct: 239 TEGLTPDDVPALADRVRHSMLTVFREISTDGRGGG 273


>gi|15100175 1-acylglycerol-3-phosphate O-acyltransferase 1 [Homo
           sapiens]
          Length = 283

 Score =  181 bits (458), Expect = 7e-46
 Identities = 109/275 (39%), Positives = 150/275 (54%), Gaps = 42/275 (15%)

Query: 1   MELWPCLAAALLLLLLLVQL--------SRAAEFYAKVALYCALCFTVSAVASLVCLLRH 52
           M+LWP     LLLL LL+          S +A+++ K+A Y      ++ +A  VC +R 
Sbjct: 1   MDLWPGAWMLLLLLFLLLLFLLPTLWFCSPSAKYFFKMAFYNGWILFLAVLAIPVCAVR- 59

Query: 53  GGRTVENMSIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLP 112
            GR VENM I+   +   KY YG+R EVR       ++P V+VSNHQS LD++G+MEVLP
Sbjct: 60  -GRNVENMKILRLMLLHIKYLYGIRVEVRGAHHFPPSQPYVVVSNHQSSLDLLGMMEVLP 118

Query: 113 ERCVQIAKRELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERM------------ 160
            RCV IAKRELL+ G  GL  +L GV FI+R+R+  A++VM+++ + +            
Sbjct: 119 GRCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVMSEVAQTLLTQDVRVWVFPE 178

Query: 161 --------------------VRENVPIVPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIP 200
                               V+  VPIVP+V SS+  FY  K++ FTSG   V+VL  +P
Sbjct: 179 GTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMSSYQDFYCKKERRFTSGQCQVRVLPPVP 238

Query: 201 TSGLTAADVPALVDTCHRAMRTTFLHISKTPQENG 235
           T GLT  DVPAL D    +M T F  IS   +  G
Sbjct: 239 TEGLTPDDVPALADRVRHSMLTVFREISTDGRGGG 273


>gi|44771201 integrator complex subunit 5 [Homo sapiens]
          Length = 1019

 Score = 28.5 bits (62), Expect = 5.6
 Identities = 15/51 (29%), Positives = 21/51 (41%), Gaps = 2/51 (3%)

Query: 192 TVQVLEAIPTSGLTAADVPALVDTCHRAMRTTFLHISKTPQENGATAGSGV 242
           T      I T GL   D   + + C R ++   LH+ K     G + G GV
Sbjct: 413 TAMPASVITTQGLAVPDT--VREACDRLIQLLLLHLQKLVHHRGGSPGEGV 461


>gi|215598824 ankyrin repeat and SOCS box-containing 10 isoform 2
           [Homo sapiens]
          Length = 474

 Score = 28.1 bits (61), Expect = 7.3
 Identities = 32/116 (27%), Positives = 47/116 (40%), Gaps = 10/116 (8%)

Query: 8   AAALLLLLLLVQLSRAAEFYAKVALYCALCFTVSAVAS-----LVCLLRHGGRTVENMSI 62
           AA + LLL     +   ++     L+CAL    +A+A      +  LL HG   V     
Sbjct: 352 AAVVELLLSCGVSANTMDYGGHTPLHCALQGPAAALAQSPEHVVRALLNHGAVRVWP--- 408

Query: 63  IGWFVRSFKYFYGLRFE-VRDPRRLQEARPCVIVSNHQSILDMMGLMEVLPERCVQ 117
            G   +  + FY   F  VR PR LQ    C + S+ +  L        LP R ++
Sbjct: 409 -GALPKKHQRFYSSLFALVRQPRSLQHLSRCALRSHLEGSLPQALPRLPLPPRLLR 463


>gi|24308245 RecQ-mediated genome instability protein 2 [Homo
           sapiens]
          Length = 147

 Score = 27.7 bits (60), Expect = 9.5
 Identities = 16/53 (30%), Positives = 26/53 (49%), Gaps = 4/53 (7%)

Query: 78  FEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVL-PERCVQIAKRELLFLGPV 129
           F VR   R+   RPC++   +  +   MG+++   PE C+Q  K   L   P+
Sbjct: 81  FSVRGLERVPRGRPCLVPGKYVMV---MGVVQACSPEPCLQAVKMTDLSDNPI 130


>gi|84662753 G protein-coupled receptor 149 [Homo sapiens]
          Length = 731

 Score = 27.7 bits (60), Expect = 9.5
 Identities = 14/43 (32%), Positives = 22/43 (51%), Gaps = 5/43 (11%)

Query: 30 VALYCALCFT-----VSAVASLVCLLRHGGRTVENMSIIGWFV 67
          + L+C  C       V ++ SL+ LL+   RTV +M +  W V
Sbjct: 34 IYLFCLTCLMTFAALVGSIYSLISLLKMQNRTVVSMLVASWSV 76


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.138    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,202,724
Number of Sequences: 37866
Number of extensions: 314242
Number of successful extensions: 914
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 903
Number of HSP's gapped (non-prelim): 11
length of query: 246
length of database: 18,247,518
effective HSP length: 100
effective length of query: 146
effective length of database: 14,460,918
effective search space: 2111294028
effective search space used: 2111294028
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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