Guide to the Human Genome
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Search of human proteins with 66932965

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|66932965 histamine N-methyltransferase isoform 3 [Homo
sapiens]
         (126 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|66932965 histamine N-methyltransferase isoform 3 [Homo sapiens]    254   1e-68
gi|5901970 histamine N-methyltransferase isoform 1 [Homo sapiens]     130   3e-31
gi|66932963 histamine N-methyltransferase isoform 2 [Homo sapiens]     99   1e-21
gi|119964726 insulin-like growth factor 2 receptor precursor [Ho...    27   3.2  
gi|55749789 DENN/MADD domain containing 1A isoform 2 [Homo sapiens]    27   3.2  
gi|55749779 DENN/MADD domain containing 1A isoform 1 [Homo sapiens]    27   3.2  
gi|7706687 Enah/Vasp-like [Homo sapiens]                               27   5.4  
gi|124517687 zinc finger protein 560 [Homo sapiens]                    27   5.4  
gi|21450853 oxysterol-binding protein-like protein 2 isoform 2 [...    27   5.4  
gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [H...    27   5.4  
gi|219842236 feline sarcoma oncogene isoform 4 [Homo sapiens]          26   9.2  
gi|219842233 feline sarcoma oncogene isoform 3 [Homo sapiens]          26   9.2  
gi|219842230 feline sarcoma oncogene isoform 2 [Homo sapiens]          26   9.2  
gi|4503687 feline sarcoma oncogene isoform 1 [Homo sapiens]            26   9.2  
gi|11056056 mitochondrial ribosomal protein S12 precursor [Homo ...    26   9.2  
gi|16950589 mitochondrial ribosomal protein S12 precursor [Homo ...    26   9.2  
gi|16950591 mitochondrial ribosomal protein S12 precursor [Homo ...    26   9.2  
gi|40255052 IQ motif containing with AAA domain 1 [Homo sapiens]       26   9.2  
gi|23943866 family with sequence similarity 5, member B [Homo sa...    26   9.2  

>gi|66932965 histamine N-methyltransferase isoform 3 [Homo sapiens]
          Length = 126

 Score =  254 bits (649), Expect = 1e-68
 Identities = 126/126 (100%), Positives = 126/126 (100%)

Query: 1   MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIG 60
           MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIG
Sbjct: 1   MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIG 60

Query: 61  GGADCLIRGSSRVLKRNSCFILCSTRQKDKPGMRIHDERSSELPFGAARLESKSAFPSFL 120
           GGADCLIRGSSRVLKRNSCFILCSTRQKDKPGMRIHDERSSELPFGAARLESKSAFPSFL
Sbjct: 61  GGADCLIRGSSRVLKRNSCFILCSTRQKDKPGMRIHDERSSELPFGAARLESKSAFPSFL 120

Query: 121 VSFILF 126
           VSFILF
Sbjct: 121 VSFILF 126


>gi|5901970 histamine N-methyltransferase isoform 1 [Homo sapiens]
          Length = 292

 Score =  130 bits (326), Expect = 3e-31
 Identities = 63/63 (100%), Positives = 63/63 (100%)

Query: 1  MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIG 60
          MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIG
Sbjct: 1  MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIG 60

Query: 61 GGA 63
          GGA
Sbjct: 61 GGA 63


>gi|66932963 histamine N-methyltransferase isoform 2 [Homo
          sapiens]
          Length = 51

 Score = 98.6 bits (244), Expect = 1e-21
 Identities = 46/46 (100%), Positives = 46/46 (100%)

Query: 1  MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGR 46
          MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGR
Sbjct: 1  MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGR 46


>gi|119964726 insulin-like growth factor 2 receptor precursor [Homo
           sapiens]
          Length = 2491

 Score = 27.3 bits (59), Expect = 3.2
 Identities = 12/53 (22%), Positives = 25/53 (47%)

Query: 27  TEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIGGGADCLIRGSSRVLKRNSC 79
           TE+ C +++++ K   + G   D   ++  L+  GG+  +  G   +   N C
Sbjct: 314 TEYACHRDYLESKTCSLSGEQQDVSIDLTPLAQSGGSSYISDGKEYLFYLNVC 366


>gi|55749789 DENN/MADD domain containing 1A isoform 2 [Homo sapiens]
          Length = 559

 Score = 27.3 bits (59), Expect = 3.2
 Identities = 19/79 (24%), Positives = 41/79 (51%), Gaps = 2/79 (2%)

Query: 18  SFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIG--GGADCLIRGSSRVLK 75
           + R+FL ++T+ Q  ++F+D +L  +    G +    + +++G   G+D L       ++
Sbjct: 350 AMRQFLQNATQLQLFKQFIDGRLDLLNSGEGFSDVFEEEINMGEYAGSDKLYHQWLSTVR 409

Query: 76  RNSCFILCSTRQKDKPGMR 94
           + S  IL + + K  P M+
Sbjct: 410 KGSGAILNTVKTKANPAMK 428


>gi|55749779 DENN/MADD domain containing 1A isoform 1 [Homo sapiens]
          Length = 1009

 Score = 27.3 bits (59), Expect = 3.2
 Identities = 19/79 (24%), Positives = 41/79 (51%), Gaps = 2/79 (2%)

Query: 18  SFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIG--GGADCLIRGSSRVLK 75
           + R+FL ++T+ Q  ++F+D +L  +    G +    + +++G   G+D L       ++
Sbjct: 350 AMRQFLQNATQLQLFKQFIDGRLDLLNSGEGFSDVFEEEINMGEYAGSDKLYHQWLSTVR 409

Query: 76  RNSCFILCSTRQKDKPGMR 94
           + S  IL + + K  P M+
Sbjct: 410 KGSGAILNTVKTKANPAMK 428


>gi|7706687 Enah/Vasp-like [Homo sapiens]
          Length = 418

 Score = 26.6 bits (57), Expect = 5.4
 Identities = 17/57 (29%), Positives = 26/57 (45%), Gaps = 4/57 (7%)

Query: 48  GDTKSEIKILSIGGGADCLIRGSSRVLKRNSCFILCSTRQKDKPGMRIHDERSSELP 104
           G +KS+    S GGG   L+   +++L +       +  Q DKP  +  DE   E P
Sbjct: 251 GTSKSDANRASSGGGGGGLMEEMNKLLAKRR----KAASQSDKPAEKKEDESQMEDP 303


>gi|124517687 zinc finger protein 560 [Homo sapiens]
          Length = 790

 Score = 26.6 bits (57), Expect = 5.4
 Identities = 13/28 (46%), Positives = 17/28 (60%), Gaps = 3/28 (10%)

Query: 7   SLFSDHGKYVESFRRFLNHSTEHQCMQE 34
           S+FS HGK   SFR  LN   + +C Q+
Sbjct: 265 SVFSKHGK---SFRLILNVQVQRKCTQD 289


>gi|21450853 oxysterol-binding protein-like protein 2 isoform 2
           [Homo sapiens]
          Length = 480

 Score = 26.6 bits (57), Expect = 5.4
 Identities = 15/49 (30%), Positives = 22/49 (44%), Gaps = 5/49 (10%)

Query: 23  LNHSTEHQCMQEF-----MDKKLPGIIGRIGDTKSEIKILSIGGGADCL 66
           LNH T H+C+  F       K+L  + G I D   +   +  G   +CL
Sbjct: 258 LNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLFMIYGKWTECL 306


>gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [Homo
           sapiens]
          Length = 468

 Score = 26.6 bits (57), Expect = 5.4
 Identities = 15/49 (30%), Positives = 22/49 (44%), Gaps = 5/49 (10%)

Query: 23  LNHSTEHQCMQEF-----MDKKLPGIIGRIGDTKSEIKILSIGGGADCL 66
           LNH T H+C+  F       K+L  + G I D   +   +  G   +CL
Sbjct: 246 LNHRTGHKCVLHFKPCGLFGKELHKVEGHIQDKNKKKLFMIYGKWTECL 294


>gi|219842236 feline sarcoma oncogene isoform 4 [Homo sapiens]
          Length = 694

 Score = 25.8 bits (55), Expect = 9.2
 Identities = 16/52 (30%), Positives = 25/52 (48%), Gaps = 8/52 (15%)

Query: 4   SMRSLFSDHGKYVESFRRF-LNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEI 54
           S+  LF+ H +YV   R   L+H   HQ +       LPG++  + D   E+
Sbjct: 117 SLWKLFAHHNRYVLGVRAAQLHHQHHHQLL-------LPGLLRSLQDLHEEM 161


>gi|219842233 feline sarcoma oncogene isoform 3 [Homo sapiens]
          Length = 752

 Score = 25.8 bits (55), Expect = 9.2
 Identities = 16/52 (30%), Positives = 25/52 (48%), Gaps = 8/52 (15%)

Query: 4   SMRSLFSDHGKYVESFRRF-LNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEI 54
           S+  LF+ H +YV   R   L+H   HQ +       LPG++  + D   E+
Sbjct: 175 SLWKLFAHHNRYVLGVRAAQLHHQHHHQLL-------LPGLLRSLQDLHEEM 219


>gi|219842230 feline sarcoma oncogene isoform 2 [Homo sapiens]
          Length = 764

 Score = 25.8 bits (55), Expect = 9.2
 Identities = 16/52 (30%), Positives = 25/52 (48%), Gaps = 8/52 (15%)

Query: 4   SMRSLFSDHGKYVESFRRF-LNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEI 54
           S+  LF+ H +YV   R   L+H   HQ +       LPG++  + D   E+
Sbjct: 117 SLWKLFAHHNRYVLGVRAAQLHHQHHHQLL-------LPGLLRSLQDLHEEM 161


>gi|4503687 feline sarcoma oncogene isoform 1 [Homo sapiens]
          Length = 822

 Score = 25.8 bits (55), Expect = 9.2
 Identities = 16/52 (30%), Positives = 25/52 (48%), Gaps = 8/52 (15%)

Query: 4   SMRSLFSDHGKYVESFRRF-LNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEI 54
           S+  LF+ H +YV   R   L+H   HQ +       LPG++  + D   E+
Sbjct: 175 SLWKLFAHHNRYVLGVRAAQLHHQHHHQLL-------LPGLLRSLQDLHEEM 219


>gi|11056056 mitochondrial ribosomal protein S12 precursor [Homo
           sapiens]
          Length = 138

 Score = 25.8 bits (55), Expect = 9.2
 Identities = 12/39 (30%), Positives = 20/39 (51%)

Query: 57  LSIGGGADCLIRGSSRVLKRNSCFILCSTRQKDKPGMRI 95
           LS G  A C I G    L+ +   ++   R +D PG+++
Sbjct: 85  LSTGREAVCFIPGEGHTLQEHQIVLVEGGRTQDLPGVKL 123


>gi|16950589 mitochondrial ribosomal protein S12 precursor [Homo
           sapiens]
          Length = 138

 Score = 25.8 bits (55), Expect = 9.2
 Identities = 12/39 (30%), Positives = 20/39 (51%)

Query: 57  LSIGGGADCLIRGSSRVLKRNSCFILCSTRQKDKPGMRI 95
           LS G  A C I G    L+ +   ++   R +D PG+++
Sbjct: 85  LSTGREAVCFIPGEGHTLQEHQIVLVEGGRTQDLPGVKL 123


>gi|16950591 mitochondrial ribosomal protein S12 precursor [Homo
           sapiens]
          Length = 138

 Score = 25.8 bits (55), Expect = 9.2
 Identities = 12/39 (30%), Positives = 20/39 (51%)

Query: 57  LSIGGGADCLIRGSSRVLKRNSCFILCSTRQKDKPGMRI 95
           LS G  A C I G    L+ +   ++   R +D PG+++
Sbjct: 85  LSTGREAVCFIPGEGHTLQEHQIVLVEGGRTQDLPGVKL 123


>gi|40255052 IQ motif containing with AAA domain 1 [Homo sapiens]
          Length = 822

 Score = 25.8 bits (55), Expect = 9.2
 Identities = 17/56 (30%), Positives = 31/56 (55%), Gaps = 2/56 (3%)

Query: 6  RSLFSDHGKYVESFRRFLNHSTE--HQCMQEFMDKKLPGIIGRIGDTKSEIKILSI 59
          ++L + + KYV+ FR   N   +  H   +  + K L G++GRI + K+E+  L +
Sbjct: 40 QTLATFYVKYVQIFRNLENVYDQFVHPQKRILIRKVLDGVMGRILELKNEMVELEL 95


>gi|23943866 family with sequence similarity 5, member B [Homo
           sapiens]
          Length = 783

 Score = 25.8 bits (55), Expect = 9.2
 Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 10/74 (13%)

Query: 49  DTKSEIKILSIGGGADCLIRGSSRVLKRNSCFILCSTRQKDKPGMRIHDERSSELPFGAA 108
           DT  + +   +G G   L + + R+L+R   F LC  R   +P  R+  ERS  L +   
Sbjct: 365 DTSLQHRYQQLGAGLKVLFKKTHRILRR--LFNLCK-RCHRQPRFRLPKERS--LSYWWN 419

Query: 109 RLES-----KSAFP 117
           R++S     +S FP
Sbjct: 420 RIQSLLYCGESTFP 433


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.138    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,355,985
Number of Sequences: 37866
Number of extensions: 161268
Number of successful extensions: 413
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 406
Number of HSP's gapped (non-prelim): 19
length of query: 126
length of database: 18,247,518
effective HSP length: 90
effective length of query: 36
effective length of database: 14,839,578
effective search space: 534224808
effective search space used: 534224808
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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