Guide to the Human Genome
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Search of human proteins with 66392190

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|66392190 transmembrane protein 41B [Homo sapiens]
         (291 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|66392190 transmembrane protein 41B [Homo sapiens]                  577   e-165
gi|18087813 transmembrane protein 41A [Homo sapiens]                  164   6e-41
gi|223555958 transmembrane protein 64 isoform 1 [Homo sapiens]         33   0.29 
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]       33   0.39 
gi|13994263 FERM domain containing 8 [Homo sapiens]                    30   1.9  
gi|20149598 solute carrier family 25 (mitochondrial carrier; dic...    30   1.9  
gi|223029426 solute carrier family 35, member D2 [Homo sapiens]        29   4.3  
gi|161019170 mucin 5AC [Homo sapiens]                                  29   4.3  
gi|113420453 PREDICTED: similar to ubiquitin protein ligase E3 c...    29   5.6  
gi|218749848 family with sequence similarity 38, member A [Homo ...    29   5.6  
gi|15147337 ubiquitin protein ligase E3 component n-recognin 5 [...    29   5.6  
gi|21735483 transient receptor potential cation channel, subfami...    28   9.5  
gi|55743132 ribonuclease P 40kDa subunit [Homo sapiens]                28   9.5  
gi|53828672 olfactory receptor, family 4, subfamily F, member 15...    28   9.5  

>gi|66392190 transmembrane protein 41B [Homo sapiens]
          Length = 291

 Score =  577 bits (1487), Expect = e-165
 Identities = 291/291 (100%), Positives = 291/291 (100%)

Query: 1   MAKGRVAERSQLGAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGSARMSLLILVSI 60
           MAKGRVAERSQLGAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGSARMSLLILVSI
Sbjct: 1   MAKGRVAERSQLGAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGSARMSLLILVSI 60

Query: 61  FLSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFAT 120
           FLSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFAT
Sbjct: 61  FLSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFAT 120

Query: 121 YIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLT 180
           YIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLT
Sbjct: 121 YIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLT 180

Query: 181 EKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPP 240
           EKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPP
Sbjct: 181 EKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPP 240

Query: 241 SFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQKFE 291
           SFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQKFE
Sbjct: 241 SFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQKFE 291


>gi|18087813 transmembrane protein 41A [Homo sapiens]
          Length = 264

 Score =  164 bits (416), Expect = 6e-41
 Identities = 78/242 (32%), Positives = 142/242 (58%), Gaps = 6/242 (2%)

Query: 54  LLILVSIFLSAAFVMFLVYKNFPQ---LSEEERV---NMKVPRDMDDAKALGKVLSKYKD 107
           LL L+ +F    F ++L+    P+   L   E     ++  P D+ + + L +VL +Y+ 
Sbjct: 4   LLGLLLVFAGCTFALYLLSTRLPRGRRLGSTEEAGGRSLWFPSDLAELRELSEVLREYRK 63

Query: 108 TFYVQVLVAYFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLS 167
                V + +   Y++ Q FAIPGS FL++L+G L+   L L L C+ + +GA+ CY+LS
Sbjct: 64  EHQAYVFLLFCGAYLYKQGFAIPGSSFLNVLAGALFGPWLGLLLCCVLTSVGATCCYLLS 123

Query: 168 YLVGRPVVYKYLTEKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLK 227
            + G+ +V  Y  +K     ++VE +R  L  +++FLR+ P  PNWF+N+++P++N+P+ 
Sbjct: 124 SIFGKQLVVSYFPDKVALLQRKVEENRNSLFFFLLFLRLFPMTPNWFLNLSAPILNIPIV 183

Query: 228 VFFIGTFLGVAPPSFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKLK 287
            FF    +G+ P +F+ ++ G+ L  LT+     SW+++F L+ +A+++++P    KK  
Sbjct: 184 QFFFSVLIGLIPYNFICVQTGSILSTLTSLDALFSWDTVFKLLAIAMVALIPGTLIKKFS 243

Query: 288 QK 289
           QK
Sbjct: 244 QK 245


>gi|223555958 transmembrane protein 64 isoform 1 [Homo sapiens]
          Length = 380

 Score = 33.1 bits (74), Expect = 0.29
 Identities = 33/162 (20%), Positives = 65/162 (40%), Gaps = 27/162 (16%)

Query: 131 GSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAVKWSQQV 190
           G I L++ +G+LY F L + L+            M+  L+G  + +         W    
Sbjct: 177 GYIVLNVAAGYLYGFVLGMGLM------------MVGVLIGTFIAHVVCKRLLTAWVAAR 224

Query: 191 ERHREHL------------INYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVA 238
            +  E L            +  +   R+TP +P    N    + ++ L  + + + +G+ 
Sbjct: 225 IQSSEKLSAVIRVVEGGSGLKVVALARLTP-IPFGLQNAVFSITDLSLPNYLMASSVGLL 283

Query: 239 PPSFVAIKAGTTLYQL--TTAGEAVSWNSIFILMILAVLSIL 278
           P   +    GTTL  +    A ++VS   +F L I+  + ++
Sbjct: 284 PTQLLNSYLGTTLRTMEDVIAEQSVSGYFVFCLQIIISIGLM 325


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score = 32.7 bits (73), Expect = 0.39
 Identities = 17/44 (38%), Positives = 20/44 (45%)

Query: 6    VAERSQLGAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGS 49
            V   S LG  HT PV +  A T G + P S  H    +W  A S
Sbjct: 3436 VTPSSALGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATS 3479



 Score = 32.3 bits (72), Expect = 0.50
 Identities = 17/44 (38%), Positives = 20/44 (45%)

Query: 6    VAERSQLGAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGS 49
            V   S LG  HT PV +  A T G + P S  H    +W  A S
Sbjct: 2179 VTPSSALGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATS 2222



 Score = 30.0 bits (66), Expect = 2.5
 Identities = 16/47 (34%), Positives = 20/47 (42%)

Query: 6    VAERSQLGAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGSARM 52
            V   S LG  HT PV +  A T G +   S  H    +W  A S  +
Sbjct: 2736 VTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTL 2782



 Score = 30.0 bits (66), Expect = 2.5
 Identities = 16/47 (34%), Positives = 20/47 (42%)

Query: 6    VAERSQLGAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGSARM 52
            V   S LG  HT PV +  A T G +   S  H    +W  A S  +
Sbjct: 3993 VTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTL 4039


>gi|13994263 FERM domain containing 8 [Homo sapiens]
          Length = 464

 Score = 30.4 bits (67), Expect = 1.9
 Identities = 20/61 (32%), Positives = 28/61 (45%), Gaps = 6/61 (9%)

Query: 22 DGAAGTRGLAAPGSRDHQKEKSWVEAGSARMSLLILVSIFLSAAFVMFLVYKNFPQLSEE 81
          DG  G+ G   P  R H+   S V A +A       V ++L+   V+ L  +N P LS  
Sbjct: 2  DGTEGSAGQPGPAERSHRSSVSSVGARAAD------VLVYLADDTVVPLAVENLPSLSAH 55

Query: 82 E 82
          E
Sbjct: 56 E 56


>gi|20149598 solute carrier family 25 (mitochondrial carrier;
           dicarboxylate transporter), member 10 [Homo sapiens]
          Length = 287

 Score = 30.4 bits (67), Expect = 1.9
 Identities = 13/38 (34%), Positives = 23/38 (60%)

Query: 151 LVCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAVKWSQ 188
           ++ L SGL AS C  ++Y + R  +Y+ + ++  K SQ
Sbjct: 57  ILALYSGLSASLCRQMTYSLTRFAIYETVRDRVAKGSQ 94


>gi|223029426 solute carrier family 35, member D2 [Homo sapiens]
          Length = 337

 Score = 29.3 bits (64), Expect = 4.3
 Identities = 24/74 (32%), Positives = 37/74 (50%), Gaps = 12/74 (16%)

Query: 110 YVQVLVAYFATYIFLQTFAIPGSI------FLSILSGFLYPFPLALFL---VCLCSGLGA 160
           Y  VL +Y+ + +   T A+ G+I      ++ IL G  Y F L  F+   +C+  GL  
Sbjct: 256 YSTVLCSYYNSAL---TTAVVGAIKNVSVAYIGILIGGDYIFSLLNFVGLNICMAGGLRY 312

Query: 161 SFCYMLSYLVGRPV 174
           SF  + S L  +PV
Sbjct: 313 SFLTLSSQLKPKPV 326


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score = 29.3 bits (64), Expect = 4.3
 Identities = 14/37 (37%), Positives = 17/37 (45%)

Query: 13   GAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGS 49
            G  HT PV +  A T G + P S  H    +W  A S
Sbjct: 3968 GTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATS 4004



 Score = 28.9 bits (63), Expect = 5.6
 Identities = 14/37 (37%), Positives = 17/37 (45%)

Query: 13   GAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGS 49
            G  HT PV +  A T G + P S  H    +W  A S
Sbjct: 2821 GTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATS 2857


>gi|113420453 PREDICTED: similar to ubiquitin protein ligase E3
           component n-recognin 5 isoform 1 [Homo sapiens]
          Length = 2796

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 16/53 (30%), Positives = 30/53 (56%), Gaps = 1/53 (1%)

Query: 4   GRVAERSQLGAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGSARMSLLI 56
           GR+A  + LG+  ++ VG    G+ G ++ G+RD +++   +  G  R S L+
Sbjct: 121 GRLAGNT-LGSRWSSGVGGSGGGSSGRSSAGARDSRRQTRVIRTGRDRGSGLL 172


>gi|218749848 family with sequence similarity 38, member A [Homo
           sapiens]
          Length = 2090

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 20/100 (20%), Positives = 43/100 (43%), Gaps = 7/100 (7%)

Query: 196 HLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIKAGTTLYQLT 255
           H  +Y+  L++  F   +++ +    +    ++   G  LG     F  +  GT L Q  
Sbjct: 719 HCRSYLDMLKVAVFRYLFWLVLVVVFVTGATRISIFG--LGYLLACFYLLLFGTALLQRD 776

Query: 256 TAGEAVSWNSIFILMILAV-----LSILPAIFQKKLKQKF 290
           T    V W+ + +  +  +     LS+L  +F ++++  F
Sbjct: 777 TRARLVLWDCLILYNVTVIISKNMLSLLACVFVEQMQTGF 816


>gi|15147337 ubiquitin protein ligase E3 component n-recognin 5
           [Homo sapiens]
          Length = 2799

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 16/53 (30%), Positives = 30/53 (56%), Gaps = 1/53 (1%)

Query: 4   GRVAERSQLGAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGSARMSLLI 56
           GR+A  + LG+  ++ VG    G+ G ++ G+RD +++   +  G  R S L+
Sbjct: 121 GRLAGNT-LGSRWSSGVGGSGGGSSGRSSAGARDSRRQTRVIRTGRDRGSGLL 172


>gi|21735483 transient receptor potential cation channel, subfamily
           V, member 3 [Homo sapiens]
          Length = 790

 Score = 28.1 bits (61), Expect = 9.5
 Identities = 25/91 (27%), Positives = 38/91 (41%), Gaps = 14/91 (15%)

Query: 116 AYFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVG--RP 173
           A+F    F+Q   +       ILS FLY F    +L CL   +   +  ML Y  G    
Sbjct: 520 AWFHFVFFIQAVLV-------ILSVFLYLFAYKEYLACLVLAMALGWANMLYYTRGFQSM 572

Query: 174 VVYKYLTEKAVKWSQQVERHREHLINYIIFL 204
            +Y  + +K +     +    + L  YI+FL
Sbjct: 573 GMYSVMIQKVI-----LHDVLKFLFVYIVFL 598


>gi|55743132 ribonuclease P 40kDa subunit [Homo sapiens]
          Length = 363

 Score = 28.1 bits (61), Expect = 9.5
 Identities = 21/97 (21%), Positives = 38/97 (39%), Gaps = 22/97 (22%)

Query: 117 YFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVY 176
           + +TY   +   +    +L  ++GF+ P  + L L  LC            +    P + 
Sbjct: 260 FISTYCCPEPSTVVAKAYLCTITGFILPEKICLLLEHLC------------HYFDEPKLA 307

Query: 177 KYLT-------EKAVKWSQQVERHR---EHLINYIIF 203
            ++T       +  V W +     R   EHL N++IF
Sbjct: 308 PWVTLSVQGFADSPVSWEKNEHGFRKGGEHLYNFVIF 344


>gi|53828672 olfactory receptor, family 4, subfamily F, member 15
           [Homo sapiens]
          Length = 312

 Score = 28.1 bits (61), Expect = 9.5
 Identities = 26/110 (23%), Positives = 47/110 (42%), Gaps = 24/110 (21%)

Query: 39  QKEKSWVEAGSARMSLLILVSIFLSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKAL 98
           Q+ +  V   S  +S+   V + +S  F++F V+K+                    +  L
Sbjct: 193 QELEFMVTVNSGLISVGSFVLLVISYIFILFTVWKH-------------------SSGGL 233

Query: 99  GKVLSKYKDTFYVQVLVAYFATYIFLQTFAIPGS---IFLSILSGFLYPF 145
            K LS    + +V V++ +F   +F  T+  P S    +L+I   F+ PF
Sbjct: 234 AKALSTL--SAHVTVVILFFGPLMFFYTWPSPTSHLDKYLAIFDAFITPF 281


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.140    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,307,385
Number of Sequences: 37866
Number of extensions: 424504
Number of successful extensions: 1573
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1562
Number of HSP's gapped (non-prelim): 20
length of query: 291
length of database: 18,247,518
effective HSP length: 101
effective length of query: 190
effective length of database: 14,423,052
effective search space: 2740379880
effective search space used: 2740379880
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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