Search of human proteins with 66346721

Search of human proteins with 66346721

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|66346721 mitochondrial phosphoenolpyruvate carboxykinase 2
isoform 1 precursor [Homo sapiens]
         (640 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|66346721 mitochondrial phosphoenolpyruvate carboxykinase 2 is...  1337   0.0  
gi|187281517 cytosolic phosphoenolpyruvate carboxykinase 1 [Homo...   942   0.0  
gi|66346723 mitochondrial phosphoenolpyruvate carboxykinase 2 is...   857   0.0  
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]             35   0.28 
gi|75677365 dynein heavy chain domain 3 [Homo sapiens]                 31   3.1  
gi|149158711 hypothetical protein LOC56673 [Homo sapiens]              31   4.0  
gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens]         30   5.2  
gi|28372567 zinc finger protein 575 [Homo sapiens]                     30   5.2  
gi|13129110 WD repeat domain 77 [Homo sapiens]                         30   6.8  

>gi|66346721 mitochondrial phosphoenolpyruvate carboxykinase 2
           isoform 1 precursor [Homo sapiens]
          Length = 640

 Score = 1337 bits (3460), Expect = 0.0
 Identities = 640/640 (100%), Positives = 640/640 (100%)

Query: 1   MAALYRPGLRLNWHGLSPLGWPSCRSIQTLRVLSGDLGQLPTGIRDFVEHSARLCQPEGI 60
           MAALYRPGLRLNWHGLSPLGWPSCRSIQTLRVLSGDLGQLPTGIRDFVEHSARLCQPEGI
Sbjct: 1   MAALYRPGLRLNWHGLSPLGWPSCRSIQTLRVLSGDLGQLPTGIRDFVEHSARLCQPEGI 60

Query: 61  HICDGTEAENTATLTLLEQQGLIRKLPKYNNCWLARTDPKDVARVESKTVIVTPSQRDTV 120
           HICDGTEAENTATLTLLEQQGLIRKLPKYNNCWLARTDPKDVARVESKTVIVTPSQRDTV
Sbjct: 61  HICDGTEAENTATLTLLEQQGLIRKLPKYNNCWLARTDPKDVARVESKTVIVTPSQRDTV 120

Query: 121 QLPPGGARGQLGNWMSPADFQRAVDERFPGCMQGRTMYVLPFSMGPVGSPLSRIGVQLTD 180
           QLPPGGARGQLGNWMSPADFQRAVDERFPGCMQGRTMYVLPFSMGPVGSPLSRIGVQLTD
Sbjct: 121 QLPPGGARGQLGNWMSPADFQRAVDERFPGCMQGRTMYVLPFSMGPVGSPLSRIGVQLTD 180

Query: 181 SAYVVASMRIMTRLGTPVLQALGDGDFVKCLHSVGQPLTGQGEPVSQWPCNPEKTLIGHV 240
           SAYVVASMRIMTRLGTPVLQALGDGDFVKCLHSVGQPLTGQGEPVSQWPCNPEKTLIGHV
Sbjct: 181 SAYVVASMRIMTRLGTPVLQALGDGDFVKCLHSVGQPLTGQGEPVSQWPCNPEKTLIGHV 240

Query: 241 PDQREIISFGSGYGGNSLLGKKCFALRIASRLARDEGWLAEHMLILGITSPAGKKRYVAA 300
           PDQREIISFGSGYGGNSLLGKKCFALRIASRLARDEGWLAEHMLILGITSPAGKKRYVAA
Sbjct: 241 PDQREIISFGSGYGGNSLLGKKCFALRIASRLARDEGWLAEHMLILGITSPAGKKRYVAA 300

Query: 301 AFPSACGKTNLAMMRPALPGWKVECVGDDIAWMRFDSEGRLRAINPENGFFGVAPGTSAT 360
           AFPSACGKTNLAMMRPALPGWKVECVGDDIAWMRFDSEGRLRAINPENGFFGVAPGTSAT
Sbjct: 301 AFPSACGKTNLAMMRPALPGWKVECVGDDIAWMRFDSEGRLRAINPENGFFGVAPGTSAT 360

Query: 361 TNPNAMATIQSNTIFTNVAETSDGGVYWEGIDQPLPPGVTVTSWLGKPWKPGDKEPCAHP 420
           TNPNAMATIQSNTIFTNVAETSDGGVYWEGIDQPLPPGVTVTSWLGKPWKPGDKEPCAHP
Sbjct: 361 TNPNAMATIQSNTIFTNVAETSDGGVYWEGIDQPLPPGVTVTSWLGKPWKPGDKEPCAHP 420

Query: 421 NSRFCAPARQCPIMDPAWEAPEGVPIDAIIFGGRRPKGVPLVYEAFNWRHGVFVGSAMRS 480
           NSRFCAPARQCPIMDPAWEAPEGVPIDAIIFGGRRPKGVPLVYEAFNWRHGVFVGSAMRS
Sbjct: 421 NSRFCAPARQCPIMDPAWEAPEGVPIDAIIFGGRRPKGVPLVYEAFNWRHGVFVGSAMRS 480

Query: 481 ESTAAAEHKGKIIMHDPFAMRPFFGYNFGHYLEHWLSMEGRKGAQLPRIFHVNWFRRDEA 540
           ESTAAAEHKGKIIMHDPFAMRPFFGYNFGHYLEHWLSMEGRKGAQLPRIFHVNWFRRDEA
Sbjct: 481 ESTAAAEHKGKIIMHDPFAMRPFFGYNFGHYLEHWLSMEGRKGAQLPRIFHVNWFRRDEA 540

Query: 541 GHFLWPGFGENARVLDWICRRLEGEDSARETPIGLVPKEGALDLSGLRAIDTTQLFSLPK 600
           GHFLWPGFGENARVLDWICRRLEGEDSARETPIGLVPKEGALDLSGLRAIDTTQLFSLPK
Sbjct: 541 GHFLWPGFGENARVLDWICRRLEGEDSARETPIGLVPKEGALDLSGLRAIDTTQLFSLPK 600

Query: 601 DFWEQEVRDIRSYLTEQVNQDLPKEVLAELEALERRVHKM 640
           DFWEQEVRDIRSYLTEQVNQDLPKEVLAELEALERRVHKM
Sbjct: 601 DFWEQEVRDIRSYLTEQVNQDLPKEVLAELEALERRVHKM 640


>gi|187281517 cytosolic phosphoenolpyruvate carboxykinase 1 [Homo
           sapiens]
          Length = 622

 Score =  942 bits (2436), Expect = 0.0
 Identities = 436/610 (71%), Positives = 517/610 (84%), Gaps = 1/610 (0%)

Query: 31  RVLSGDLGQLPTGIRDFVEHSARLCQPEGIHICDGTEAENTATLTLLEQQGLIRKLPKYN 90
           +V+ G L  LP  +R+F+E++A LCQP+ IHICDG+E EN   L  +E++G++R+L KY+
Sbjct: 14  KVVQGSLDSLPQAVREFLENNAELCQPDHIHICDGSEEENGRLLGQMEEEGILRRLKKYD 73

Query: 91  NCWLARTDPKDVARVESKTVIVTPSQRDTVQLPPGGARGQLGNWMSPADFQRAVDERFPG 150
           NCWLA TDP+DVAR+ESKTVIVT  QRDTV +P  G   QLG WMS  DF++A + RFPG
Sbjct: 74  NCWLALTDPRDVARIESKTVIVTQEQRDTVPIPKTGL-SQLGRWMSEEDFEKAFNARFPG 132

Query: 151 CMQGRTMYVLPFSMGPVGSPLSRIGVQLTDSAYVVASMRIMTRLGTPVLQALGDGDFVKC 210
           CM+GRTMYV+PFSMGP+GSPLS+IG++LTDS YVVASMRIMTR+GTPVL+A+GDG+FVKC
Sbjct: 133 CMKGRTMYVIPFSMGPLGSPLSKIGIELTDSPYVVASMRIMTRMGTPVLEAVGDGEFVKC 192

Query: 211 LHSVGQPLTGQGEPVSQWPCNPEKTLIGHVPDQREIISFGSGYGGNSLLGKKCFALRIAS 270
           LHSVG PL  Q   V+ WPCNPE TLI H+PD+REIISFGSGYGGNSLLGKKCFALR+AS
Sbjct: 193 LHSVGCPLPLQKPLVNNWPCNPELTLIAHLPDRREIISFGSGYGGNSLLGKKCFALRMAS 252

Query: 271 RLARDEGWLAEHMLILGITSPAGKKRYVAAAFPSACGKTNLAMMRPALPGWKVECVGDDI 330
           RLA++EGWLAEHMLILGIT+P G+K+Y+AAAFPSACGKTNLAMM P+LPGWKVECVGDDI
Sbjct: 253 RLAKEEGWLAEHMLILGITNPEGEKKYLAAAFPSACGKTNLAMMNPSLPGWKVECVGDDI 312

Query: 331 AWMRFDSEGRLRAINPENGFFGVAPGTSATTNPNAMATIQSNTIFTNVAETSDGGVYWEG 390
           AWM+FD++G LRAINPENGFFGVAPGTS  TNPNA+ TIQ NTIFTNVAETSDGGVYWEG
Sbjct: 313 AWMKFDAQGHLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNVAETSDGGVYWEG 372

Query: 391 IDQPLPPGVTVTSWLGKPWKPGDKEPCAHPNSRFCAPARQCPIMDPAWEAPEGVPIDAII 450
           ID+PL  GVT+TSW  K W   D EPCAHPNSRFC PA QCPI+D AWE+PEGVPI+ II
Sbjct: 373 IDEPLASGVTITSWKNKEWSSEDGEPCAHPNSRFCTPASQCPIIDAAWESPEGVPIEGII 432

Query: 451 FGGRRPKGVPLVYEAFNWRHGVFVGSAMRSESTAAAEHKGKIIMHDPFAMRPFFGYNFGH 510
           FGGRRP GVPLVYEA +W+HGVFVG+AMRSE+TAAAEHKGKIIMHDPFAMRPFFGYNFG 
Sbjct: 433 FGGRRPAGVPLVYEALSWQHGVFVGAAMRSEATAAAEHKGKIIMHDPFAMRPFFGYNFGK 492

Query: 511 YLEHWLSMEGRKGAQLPRIFHVNWFRRDEAGHFLWPGFGENARVLDWICRRLEGEDSARE 570
           YL HWLSM     A+LP+IFHVNWFR+D+ G FLWPGFGEN+RVL+W+  R++G+ S + 
Sbjct: 493 YLAHWLSMAQHPAAKLPKIFHVNWFRKDKEGKFLWPGFGENSRVLEWMFNRIDGKASTKL 552

Query: 571 TPIGLVPKEGALDLSGLRAIDTTQLFSLPKDFWEQEVRDIRSYLTEQVNQDLPKEVLAEL 630
           TPIG +PKE AL+L GL  I+  +LFS+ K+FWE+EV DI  YL +QVN DLP E+  E+
Sbjct: 553 TPIGYIPKEDALNLKGLGHINMMELFSISKEFWEKEVEDIEKYLEDQVNADLPCEIEREI 612

Query: 631 EALERRVHKM 640
            AL++R+ +M
Sbjct: 613 LALKQRISQM 622


>gi|66346723 mitochondrial phosphoenolpyruvate carboxykinase 2
           isoform 2 precursor [Homo sapiens]
          Length = 441

 Score =  857 bits (2213), Expect = 0.0
 Identities = 412/412 (100%), Positives = 412/412 (100%)

Query: 1   MAALYRPGLRLNWHGLSPLGWPSCRSIQTLRVLSGDLGQLPTGIRDFVEHSARLCQPEGI 60
           MAALYRPGLRLNWHGLSPLGWPSCRSIQTLRVLSGDLGQLPTGIRDFVEHSARLCQPEGI
Sbjct: 1   MAALYRPGLRLNWHGLSPLGWPSCRSIQTLRVLSGDLGQLPTGIRDFVEHSARLCQPEGI 60

Query: 61  HICDGTEAENTATLTLLEQQGLIRKLPKYNNCWLARTDPKDVARVESKTVIVTPSQRDTV 120
           HICDGTEAENTATLTLLEQQGLIRKLPKYNNCWLARTDPKDVARVESKTVIVTPSQRDTV
Sbjct: 61  HICDGTEAENTATLTLLEQQGLIRKLPKYNNCWLARTDPKDVARVESKTVIVTPSQRDTV 120

Query: 121 QLPPGGARGQLGNWMSPADFQRAVDERFPGCMQGRTMYVLPFSMGPVGSPLSRIGVQLTD 180
           QLPPGGARGQLGNWMSPADFQRAVDERFPGCMQGRTMYVLPFSMGPVGSPLSRIGVQLTD
Sbjct: 121 QLPPGGARGQLGNWMSPADFQRAVDERFPGCMQGRTMYVLPFSMGPVGSPLSRIGVQLTD 180

Query: 181 SAYVVASMRIMTRLGTPVLQALGDGDFVKCLHSVGQPLTGQGEPVSQWPCNPEKTLIGHV 240
           SAYVVASMRIMTRLGTPVLQALGDGDFVKCLHSVGQPLTGQGEPVSQWPCNPEKTLIGHV
Sbjct: 181 SAYVVASMRIMTRLGTPVLQALGDGDFVKCLHSVGQPLTGQGEPVSQWPCNPEKTLIGHV 240

Query: 241 PDQREIISFGSGYGGNSLLGKKCFALRIASRLARDEGWLAEHMLILGITSPAGKKRYVAA 300
           PDQREIISFGSGYGGNSLLGKKCFALRIASRLARDEGWLAEHMLILGITSPAGKKRYVAA
Sbjct: 241 PDQREIISFGSGYGGNSLLGKKCFALRIASRLARDEGWLAEHMLILGITSPAGKKRYVAA 300

Query: 301 AFPSACGKTNLAMMRPALPGWKVECVGDDIAWMRFDSEGRLRAINPENGFFGVAPGTSAT 360
           AFPSACGKTNLAMMRPALPGWKVECVGDDIAWMRFDSEGRLRAINPENGFFGVAPGTSAT
Sbjct: 301 AFPSACGKTNLAMMRPALPGWKVECVGDDIAWMRFDSEGRLRAINPENGFFGVAPGTSAT 360

Query: 361 TNPNAMATIQSNTIFTNVAETSDGGVYWEGIDQPLPPGVTVTSWLGKPWKPG 412
           TNPNAMATIQSNTIFTNVAETSDGGVYWEGIDQPLPPGVTVTSWLGKPWKPG
Sbjct: 361 TNPNAMATIQSNTIFTNVAETSDGGVYWEGIDQPLPPGVTVTSWLGKPWKPG 412


>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
          Length = 4391

 Score = 34.7 bits (78), Expect = 0.28
 Identities = 26/76 (34%), Positives = 39/76 (51%), Gaps = 7/76 (9%)

Query: 119  TVQLPPGGARGQLGNW--MSPADFQRAVDERFPG----CMQGRTMYVLPFSMGPVGSPLS 172
            TV+  P GA+   GN+  +    F   + E + G       G+  Y L ++ GP GSPLS
Sbjct: 1372 TVEPVPEGAQLSFGNFAQLGHESFYWQLPETYQGDKVAAYGGKLRYTLSYTAGPQGSPLS 1431

Query: 173  RIGVQLT-DSAYVVAS 187
               VQ+T ++  +VAS
Sbjct: 1432 DPDVQITGNNIMLVAS 1447


>gi|75677365 dynein heavy chain domain 3 [Homo sapiens]
          Length = 4427

 Score = 31.2 bits (69), Expect = 3.1
 Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 8/67 (11%)

Query: 232  PEKTLIGHVPDQREIISFGSGYGGNSLLGKKCFAL--RIASRLARDEGWLAEHMLILGIT 289
            P+ TLI       EII FG G+G   +L KK + L      +L+R + +      +  + 
Sbjct: 1931 PDSTLIA------EIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLL 1984

Query: 290  SPAGKKR 296
              AGKKR
Sbjct: 1985 RYAGKKR 1991


>gi|149158711 hypothetical protein LOC56673 [Homo sapiens]
          Length = 467

 Score = 30.8 bits (68), Expect = 4.0
 Identities = 17/54 (31%), Positives = 21/54 (38%), Gaps = 5/54 (9%)

Query: 388 WEGIDQPLPPGVTVTSWLGKPWKPGDKEPCAHPNSRFCAPARQCPIMDPAWEAP 441
           W+G   P     T    L  PW  G K    H +S  C       + DPAW+ P
Sbjct: 26  WDGAAPPWDLSFTYPFALQAPWLTGHKPLARHASSCPC-----LHVADPAWQGP 74


>gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens]
          Length = 438

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 20/47 (42%), Positives = 22/47 (46%), Gaps = 2/47 (4%)

Query: 220 GQGEPVSQWPCN-PEKTLIGHVPDQREII-SFGSGYGGNSLLGKKCF 264
           G GE    W    PE  L+GH P +R I  SF  G  G   LG  CF
Sbjct: 42  GLGEKFPTWETTKPELELLGHNPRRRRITSSFTIGLRGLINLGNTCF 88


>gi|28372567 zinc finger protein 575 [Homo sapiens]
          Length = 245

 Score = 30.4 bits (67), Expect = 5.2
 Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 10/72 (13%)

Query: 397 PGVTVTSWLGKPWKPGDKEPCAHPNSRFCAPARQCPIMDPAWEAPEGVPIDAIIFGGRRP 456
           PG T ++  G P +P  + P   P+        +CP  D A+  P  +    +  GG RP
Sbjct: 41  PGPTASA--GSPPRPRRRPPPQRPH--------RCPDCDKAFSYPSKLATHRLAHGGARP 90

Query: 457 KGVPLVYEAFNW 468
              P   +AF++
Sbjct: 91  HPCPDCPKAFSY 102


>gi|13129110 WD repeat domain 77 [Homo sapiens]
          Length = 342

 Score = 30.0 bits (66), Expect = 6.8
 Identities = 15/43 (34%), Positives = 19/43 (44%), Gaps = 4/43 (9%)

Query: 404 WLGKPWKPGDKEPCAHPNSRFCAPARQ--CPIMDPAWEAPEGV 444
           W G  W    K+PCA PN  FC+   Q    + D  W    G+
Sbjct: 54  WAGSLWL--FKDPCAAPNEGFCSAGVQTEAGVADLTWVGERGI 94


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.138    0.446 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,566,849
Number of Sequences: 37866
Number of extensions: 1401958
Number of successful extensions: 2732
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 2725
Number of HSP's gapped (non-prelim): 11
length of query: 640
length of database: 18,247,518
effective HSP length: 109
effective length of query: 531
effective length of database: 14,120,124
effective search space: 7497785844
effective search space used: 7497785844
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.