Search of human proteins with 63003910

Search of human proteins with 63003910

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|63003910 ATPase, H+ transporting, lysosomal accessory
protein 1-like [Homo sapiens]
         (224 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|63003910 ATPase, H+ transporting, lysosomal accessory protein...   441   e-124
gi|17136148 ATPase, H+ transporting, lysosomal accessory protein...   101   5e-22
gi|4504957 lysosomal-associated membrane protein 2 isoform A pre...    42   4e-04
gi|169790833 lysosomal-associated membrane protein 2 isoform C p...    40   0.002
gi|7669503 lysosomal-associated membrane protein 2 isoform B pre...    39   0.003
gi|112380628 lysosomal-associated membrane protein 1 [Homo sapiens]    30   1.3  
gi|12232395 lipid phosphate phosphatase-related protein type 2 [...    28   6.3  
gi|194018513 patched domain containing 3 [Homo sapiens]                28   8.3  

>gi|63003910 ATPase, H+ transporting, lysosomal accessory protein
           1-like [Homo sapiens]
          Length = 224

 Score =  441 bits (1133), Expect = e-124
 Identities = 224/224 (100%), Positives = 224/224 (100%)

Query: 1   MRLWKARVLKLVLKTAKDSRLGLNSKWLSLKLGDAGNPRSLAIRFILTNYNKLSIQSWFS 60
           MRLWKARVLKLVLKTAKDSRLGLNSKWLSLKLGDAGNPRSLAIRFILTNYNKLSIQSWFS
Sbjct: 1   MRLWKARVLKLVLKTAKDSRLGLNSKWLSLKLGDAGNPRSLAIRFILTNYNKLSIQSWFS 60

Query: 61  LRRVEIISNNSIQAVFNPTGVYAPSGYSYRCQRVGSLQQDQALLLPSDTDDGSSLWEVTF 120
           LRRVEIISNNSIQAVFNPTGVYAPSGYSYRCQRVGSLQQDQALLLPSDTDDGSSLWEVTF
Sbjct: 61  LRRVEIISNNSIQAVFNPTGVYAPSGYSYRCQRVGSLQQDQALLLPSDTDDGSSLWEVTF 120

Query: 121 IDFQIQGFAIKGGRFTKAQDCASSFSPAFLIGLAMSLILLLVLAYALHMLIYLRYLDQQY 180
           IDFQIQGFAIKGGRFTKAQDCASSFSPAFLIGLAMSLILLLVLAYALHMLIYLRYLDQQY
Sbjct: 121 IDFQIQGFAIKGGRFTKAQDCASSFSPAFLIGLAMSLILLLVLAYALHMLIYLRYLDQQY 180

Query: 181 DLIASPAHFSQLKARDTAEEKELLRSQGAECYKLRSQQISKIYV 224
           DLIASPAHFSQLKARDTAEEKELLRSQGAECYKLRSQQISKIYV
Sbjct: 181 DLIASPAHFSQLKARDTAEEKELLRSQGAECYKLRSQQISKIYV 224


>gi|17136148 ATPase, H+ transporting, lysosomal accessory protein 1
           precursor [Homo sapiens]
          Length = 470

 Score =  101 bits (252), Expect = 5e-22
 Identities = 55/140 (39%), Positives = 84/140 (60%), Gaps = 5/140 (3%)

Query: 40  SLAIRFILTN-YNKLSIQSWFSLRRVEIISNNSIQAVFNPTGVYAPSGYSYRCQRVGSLQ 98
           ++  +FIL N    +S + WF++ R+E+ SN S+ A FN + V  PS YS+ C+ V SL 
Sbjct: 320 TVTFKFILANRLYPVSARHWFTMERLEVHSNGSV-AYFNASQVTGPSIYSFHCEYVSSLS 378

Query: 99  QDQALLLPSDTDDGSSLWEVTFIDFQIQGFAIKGGRFTKAQDCASSFSPAFLIGLAMSLI 158
           +  +LL+        S W++   DFQIQ F + G +F+ A DCAS FSP   +GL  SL 
Sbjct: 379 KKGSLLVARTQP---SPWQMMLQDFQIQAFNVMGEQFSYASDCASFFSPGIWMGLLTSLF 435

Query: 159 LLLVLAYALHMLIYLRYLDQ 178
           +L +  Y LHM++ L+ +D+
Sbjct: 436 MLFIFTYGLHMILSLKTMDR 455


>gi|4504957 lysosomal-associated membrane protein 2 isoform A
           precursor [Homo sapiens]
          Length = 410

 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 31/113 (27%), Positives = 54/113 (47%), Gaps = 21/113 (18%)

Query: 59  FSLRRVEI---ISNNSIQAVFNPTGVY--APSGYSYRCQRVGSLQQDQALLLPSDTDDGS 113
           F L+ V I   + N S+ ++ N    Y  AP G SY C +               T   S
Sbjct: 294 FYLKEVNISMYLVNGSVFSIANNNLSYWDAPLGSSYMCNK-------------EQTVSVS 340

Query: 114 SLWEVTFIDFQIQGFAIKGGRFTKAQDCAS---SFSPAFLIGLAMSLILLLVL 163
             +++   D ++Q F +  G+++ AQDC++   +F     +G A++ +L+LVL
Sbjct: 341 GAFQINTFDLRVQPFNVTQGKYSTAQDCSADDDNFLVPIAVGAALAGVLILVL 393


>gi|169790833 lysosomal-associated membrane protein 2 isoform C
           precursor [Homo sapiens]
          Length = 411

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 29/119 (24%), Positives = 57/119 (47%), Gaps = 20/119 (16%)

Query: 59  FSLRRVEI---ISNNSIQAVFNPTGVY--APSGYSYRCQRVGSLQQDQALLLPSDTDDGS 113
           F L+ V I   + N S+ ++ N    Y  AP G SY C +               T   S
Sbjct: 294 FYLKEVNISMYLVNGSVFSIANNNLSYWDAPLGSSYMCNK-------------EQTVSVS 340

Query: 114 SLWEVTFIDFQIQGFAIKGGRFTKAQDCASSFSPAFLIGLAMSLIL--LLVLAYALHML 170
             +++   D ++Q F +  G+++ A++C++     FLI +A+ + L  L+++ +  +M+
Sbjct: 341 GAFQINTFDLRVQPFNVTQGKYSTAEECSADSDLNFLIPVAVGVALGFLIIVVFISYMI 399


>gi|7669503 lysosomal-associated membrane protein 2 isoform B
           precursor [Homo sapiens]
          Length = 410

 Score = 39.3 bits (90), Expect = 0.003
 Identities = 30/118 (25%), Positives = 56/118 (47%), Gaps = 22/118 (18%)

Query: 59  FSLRRVEI---ISNNSIQAVFNPTGVY--APSGYSYRCQRVGSLQQDQALLLPSDTDDGS 113
           F L+ V I   + N S+ ++ N    Y  AP G SY C +               T   S
Sbjct: 294 FYLKEVNISMYLVNGSVFSIANNNLSYWDAPLGSSYMCNK-------------EQTVSVS 340

Query: 114 SLWEVTFIDFQIQGFAIKGGRFTKAQDCA---SSFSPAFLIGLAMS-LILLLVLAYAL 167
             +++   D ++Q F +  G+++ AQ+C+    +     ++G  +S LI+++V+AY +
Sbjct: 341 GAFQINTFDLRVQPFNVTQGKYSTAQECSLDDDTILIPIIVGAGLSGLIIVIVIAYVI 398


>gi|112380628 lysosomal-associated membrane protein 1 [Homo sapiens]
          Length = 417

 Score = 30.4 bits (67), Expect = 1.3
 Identities = 23/102 (22%), Positives = 44/102 (43%), Gaps = 23/102 (22%)

Query: 68  SNNSIQAVFNPTGVYAPSGYSYRCQRVGSLQQDQALLLPSDTDDGSSLWEVTFIDFQIQG 127
           +N S++A+       A  G SY+C     ++  +A             + V      +Q 
Sbjct: 321 ANGSLRAL------QATVGNSYKCNAEEHVRVTKA-------------FSVNIFKVWVQA 361

Query: 128 FAIKGGRFTKAQDCA----SSFSPAFLIGLAMSLILLLVLAY 165
           F ++GG+F   ++C     S   P  + G    L+L++++AY
Sbjct: 362 FKVEGGQFGSVEECLLDENSMLIPIAVGGALAGLVLIVLIAY 403


>gi|12232395 lipid phosphate phosphatase-related protein type 2
           [Homo sapiens]
          Length = 343

 Score = 28.1 bits (61), Expect = 6.3
 Identities = 11/26 (42%), Positives = 15/26 (57%)

Query: 128 FAIKGGRFTKAQDCASSFSPAFLIGL 153
           F +KG R  K   C +   PAFL+G+
Sbjct: 228 FRVKGSRLVKPSLCLALLCPAFLVGV 253


>gi|194018513 patched domain containing 3 [Homo sapiens]
          Length = 767

 Score = 27.7 bits (60), Expect = 8.3
 Identities = 12/40 (30%), Positives = 25/40 (62%)

Query: 143 SSFSPAFLIGLAMSLILLLVLAYALHMLIYLRYLDQQYDL 182
           + F   +++G ++ +  LL+ A A+ +L YL+  D +YD+
Sbjct: 298 TGFFGGYILGGSLGMGQLLLRAKAMRLLYYLKTEDPEYDV 337


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.136    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,574,752
Number of Sequences: 37866
Number of extensions: 291380
Number of successful extensions: 627
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 619
Number of HSP's gapped (non-prelim): 8
length of query: 224
length of database: 18,247,518
effective HSP length: 98
effective length of query: 126
effective length of database: 14,536,650
effective search space: 1831617900
effective search space used: 1831617900
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.