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Search of human proteins with 61966717
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|61966717 arylacetamide deacetylase-like 4 [Homo sapiens]
(407 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|61966717 arylacetamide deacetylase-like 4 [Homo sapiens] 835 0.0
gi|157041239 arylacetamide deacetylase-like 3 isoform 1 [Homo sa... 413 e-115
gi|157041237 arylacetamide deacetylase-like 3 isoform 2 [Homo sa... 331 6e-91
gi|68299767 arylacetamide deacetylase [Homo sapiens] 198 8e-51
gi|68051721 arylacetamide deacetylase-like 1 isoform b [Homo sap... 189 5e-48
gi|226423947 arylacetamide deacetylase-like 1 isoform a [Homo sa... 186 3e-47
gi|206597554 arylacetamide deacetylase-like 2 [Homo sapiens] 169 4e-42
gi|226423952 arylacetamide deacetylase-like 1 isoform c [Homo sa... 155 6e-38
gi|226423950 arylacetamide deacetylase-like 1 isoform c [Homo sa... 155 6e-38
gi|21328446 hormone-sensitive lipase [Homo sapiens] 41 0.002
gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens] 40 0.004
gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens] 40 0.004
gi|219521907 carboxylesterase 7 isoform 1 [Homo sapiens] 40 0.004
gi|21450749 carboxylesterase 7 isoform 2 [Homo sapiens] 40 0.004
gi|169216018 PREDICTED: similar to hCG40360 [Homo sapiens] 39 0.006
gi|169215613 PREDICTED: similar to hCG40360 [Homo sapiens] 39 0.006
gi|33563374 carboxylesterase 3 [Homo sapiens] 35 0.093
gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens] 35 0.12
gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens] 35 0.12
gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens] 35 0.12
gi|148536848 carboxyl ester lipase precursor [Homo sapiens] 33 0.36
gi|115529439 carboxylesterase 8 (putative) [Homo sapiens] 33 0.61
gi|239752162 PREDICTED: similar to hCG40360 [Homo sapiens] 32 0.79
gi|7662470 neuroligin 1 [Homo sapiens] 32 1.3
gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo sa... 30 3.9
gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo sa... 30 3.9
gi|23308553 spermatogenesis associated 13 [Homo sapiens] 30 3.9
gi|15011979 Rho guanine nucleotide exchange factor 4 isoform a [... 30 3.9
gi|15011981 Rho guanine nucleotide exchange factor 4 isoform b [... 30 3.9
gi|194272176 phospholipase D1 isoform b [Homo sapiens] 29 6.7
>gi|61966717 arylacetamide deacetylase-like 4 [Homo sapiens]
Length = 407
Score = 835 bits (2158), Expect = 0.0
Identities = 407/407 (100%), Positives = 407/407 (100%)
Query: 1 MAVPWLVLLLALPIFFLGVFVWAVFEHFLTTDIPATLQHPAKLRFLHCIFLYLVTLGNIF 60
MAVPWLVLLLALPIFFLGVFVWAVFEHFLTTDIPATLQHPAKLRFLHCIFLYLVTLGNIF
Sbjct: 1 MAVPWLVLLLALPIFFLGVFVWAVFEHFLTTDIPATLQHPAKLRFLHCIFLYLVTLGNIF 60
Query: 61 EKLGICSMPKFIRFLHDSVRIKKDPELVVTDLRFGTIPVRLFQPKAASSRPRRGIIFYHG 120
EKLGICSMPKFIRFLHDSVRIKKDPELVVTDLRFGTIPVRLFQPKAASSRPRRGIIFYHG
Sbjct: 61 EKLGICSMPKFIRFLHDSVRIKKDPELVVTDLRFGTIPVRLFQPKAASSRPRRGIIFYHG 120
Query: 121 GATVFGSLDCYHGLCNYLARETESVLLMIGYRKLPDHHSPALFQDCMNASIHFLKALETY 180
GATVFGSLDCYHGLCNYLARETESVLLMIGYRKLPDHHSPALFQDCMNASIHFLKALETY
Sbjct: 121 GATVFGSLDCYHGLCNYLARETESVLLMIGYRKLPDHHSPALFQDCMNASIHFLKALETY 180
Query: 181 GVDPSRVVVCGESVGGAAVAAITQALVGRSDLPRIRAQVLIYPVVQAFCLQLPSFQQNQN 240
GVDPSRVVVCGESVGGAAVAAITQALVGRSDLPRIRAQVLIYPVVQAFCLQLPSFQQNQN
Sbjct: 181 GVDPSRVVVCGESVGGAAVAAITQALVGRSDLPRIRAQVLIYPVVQAFCLQLPSFQQNQN 240
Query: 241 VPLLSRKFMVTSLCNYLAIDLSWRDAILNGTCVPPDVWRKYEKWLSPDNIPKKFKNRGYQ 300
VPLLSRKFMVTSLCNYLAIDLSWRDAILNGTCVPPDVWRKYEKWLSPDNIPKKFKNRGYQ
Sbjct: 241 VPLLSRKFMVTSLCNYLAIDLSWRDAILNGTCVPPDVWRKYEKWLSPDNIPKKFKNRGYQ 300
Query: 301 PWSPGPFNEAAYLEAKHMLDVENSPLIADDEVIAQLPEAFLVSCENDILRDDSLLYKKRL 360
PWSPGPFNEAAYLEAKHMLDVENSPLIADDEVIAQLPEAFLVSCENDILRDDSLLYKKRL
Sbjct: 301 PWSPGPFNEAAYLEAKHMLDVENSPLIADDEVIAQLPEAFLVSCENDILRDDSLLYKKRL 360
Query: 361 EDQGVRVTWYHLYDGFHGSIIFFDKKALSFPCSLKIVNAVVSYIKGI 407
EDQGVRVTWYHLYDGFHGSIIFFDKKALSFPCSLKIVNAVVSYIKGI
Sbjct: 361 EDQGVRVTWYHLYDGFHGSIIFFDKKALSFPCSLKIVNAVVSYIKGI 407
>gi|157041239 arylacetamide deacetylase-like 3 isoform 1 [Homo
sapiens]
Length = 350
Score = 413 bits (1062), Expect = e-115
Identities = 195/349 (55%), Positives = 257/349 (73%)
Query: 59 IFEKLGICSMPKFIRFLHDSVRIKKDPELVVTDLRFGTIPVRLFQPKAASSRPRRGIIFY 118
IFEKL ICSMP+F F+ D +K DP++VVTD RFGTIPV+L+Q KA++ + GI++Y
Sbjct: 2 IFEKLRICSMPQFFCFMQDLPPLKYDPDVVVTDFRFGTIPVKLYQSKASTCTLKPGIVYY 61
Query: 119 HGGATVFGSLDCYHGLCNYLARETESVLLMIGYRKLPDHHSPALFQDCMNASIHFLKALE 178
HGG V GSL +HG+C+ L +E++SV+L +GYRKLP H P +DC+ A+IHFLK+L+
Sbjct: 62 HGGGGVMGSLKTHHGICSRLCKESDSVVLAVGYRKLPKHKFPVPVRDCLVATIHFLKSLD 121
Query: 179 TYGVDPSRVVVCGESVGGAAVAAITQALVGRSDLPRIRAQVLIYPVVQAFCLQLPSFQQN 238
YGVDP+RVVVCG+S GGA A + Q LV R DLPRIRAQ+LIY ++QA LQ PSFQQ
Sbjct: 122 AYGVDPARVVVCGDSFGGAIAAVVCQQLVDRPDLPRIRAQILIYAILQALDLQTPSFQQR 181
Query: 239 QNVPLLSRKFMVTSLCNYLAIDLSWRDAILNGTCVPPDVWRKYEKWLSPDNIPKKFKNRG 298
+N+PLL+ F+ L SW++ I+ G +P +VW KY KWL P+NIP++FK RG
Sbjct: 182 KNIPLLTWSFICYCFFQNLDFSSSWQEVIMKGAHLPAEVWEKYRKWLGPENIPERFKERG 241
Query: 299 YQPWSPGPFNEAAYLEAKHMLDVENSPLIADDEVIAQLPEAFLVSCENDILRDDSLLYKK 358
YQ P NEAAYLE +LDV SPLIA+D++++QLPE +VSCE D LRD+SLLYKK
Sbjct: 242 YQLKPHEPMNEAAYLEVSVVLDVMCSPLIAEDDIVSQLPETCIVSCEYDALRDNSLLYKK 301
Query: 359 RLEDQGVRVTWYHLYDGFHGSIIFFDKKALSFPCSLKIVNAVVSYIKGI 407
RLED GV VTW+H+ DGFHG + D L FPCS++I++A+V ++KG+
Sbjct: 302 RLEDLGVPVTWHHMEDGFHGVLRTIDMSFLHFPCSMRILSALVQFVKGL 350
>gi|157041237 arylacetamide deacetylase-like 3 isoform 2 [Homo
sapiens]
Length = 280
Score = 331 bits (849), Expect = 6e-91
Identities = 154/280 (55%), Positives = 206/280 (73%)
Query: 128 LDCYHGLCNYLARETESVLLMIGYRKLPDHHSPALFQDCMNASIHFLKALETYGVDPSRV 187
++ +HG+C+ L +E++SV+L +GYRKLP H P +DC+ A+IHFLK+L+ YGVDP+RV
Sbjct: 1 METHHGICSRLCKESDSVVLAVGYRKLPKHKFPVPVRDCLVATIHFLKSLDAYGVDPARV 60
Query: 188 VVCGESVGGAAVAAITQALVGRSDLPRIRAQVLIYPVVQAFCLQLPSFQQNQNVPLLSRK 247
VVCG+S GGA A + Q LV R DLPRIRAQ+LIY ++QA LQ PSFQQ +N+PLL+
Sbjct: 61 VVCGDSFGGAIAAVVCQQLVDRPDLPRIRAQILIYAILQALDLQTPSFQQRKNIPLLTWS 120
Query: 248 FMVTSLCNYLAIDLSWRDAILNGTCVPPDVWRKYEKWLSPDNIPKKFKNRGYQPWSPGPF 307
F+ L SW++ I+ G +P +VW KY KWL P+NIP++FK RGYQ P
Sbjct: 121 FICYCFFQNLDFSSSWQEVIMKGAHLPAEVWEKYRKWLGPENIPERFKERGYQLKPHEPM 180
Query: 308 NEAAYLEAKHMLDVENSPLIADDEVIAQLPEAFLVSCENDILRDDSLLYKKRLEDQGVRV 367
NEAAYLE +LDV SPLIA+D++++QLPE +VSCE D LRD+SLLYKKRLED GV V
Sbjct: 181 NEAAYLEVSVVLDVMCSPLIAEDDIVSQLPETCIVSCEYDALRDNSLLYKKRLEDLGVPV 240
Query: 368 TWYHLYDGFHGSIIFFDKKALSFPCSLKIVNAVVSYIKGI 407
TW+H+ DGFHG + D L FPCS++I++A+V ++KG+
Sbjct: 241 TWHHMEDGFHGVLRTIDMSFLHFPCSMRILSALVQFVKGL 280
>gi|68299767 arylacetamide deacetylase [Homo sapiens]
Length = 399
Score = 198 bits (503), Expect = 8e-51
Identities = 126/396 (31%), Positives = 204/396 (51%), Gaps = 17/396 (4%)
Query: 19 VFVWAVFEHFLTTDIPATLQHPAKLRFLHCIFLYLVTLGNIFEKLGICSMPKFIRFL--H 76
+ V + +++ T +P ++ P ++ +++ + L E LG+ + +
Sbjct: 9 LIVGILIAYYIYTPLPDNVEEPWRMMWINAHLKTIQNLATFVELLGLHHFMDSFKVVGSF 68
Query: 77 DSVRIKKDPELVVTDLRFGTIPVRLFQPKAASSRPRRGIIFYHGGATVFGS--LDCYHGL 134
D V D + VT+ +F I VR++ PK S RRG+ + HGG GS L Y L
Sbjct: 69 DEVPPTSDENVTVTETKFNNILVRVYVPKRKSEALRRGLFYIHGGGWCVGSAALSGYDLL 128
Query: 135 CNYLARETESVLLMIGYRKLPDHHSPALFQDCMNASIHFL--KALETYGVDPSRVVVCGE 192
+ A ++V++ YR P +H P F+D NA FL K L YGV+P R+ + G+
Sbjct: 129 SRWTADRLDAVVVSTNYRLAPKYHFPIQFEDVYNALRWFLRKKVLAKYGVNPERIGISGD 188
Query: 193 SVGGAAVAAITQALVGRSDLP-RIRAQVLIYPVVQAFCLQLPSFQQNQNVPLLSRKFMVT 251
S GG AA+TQ L+ D+ +++ Q LIYP +Q + LPS+Q+N N LS+ MV
Sbjct: 189 SAGGNLAAAVTQQLLDDPDVKIKLKIQSLIYPALQPLDVDLPSYQENSNFLFLSKSLMVR 248
Query: 252 SLCNYLAIDLSWRDAILNGTCVPPDVWR--KYEKWLSPDNIPKKFKNRGYQPWSPGPFNE 309
Y D S A+L+ VP + K+ W S +P++F +G+ +P +
Sbjct: 249 FWSEYFTTDRSLEKAMLSRQHVPVESSHLFKFVNWSSL--LPERFI-KGHVYNNPNYGSS 305
Query: 310 AAYLEAKHMLDVENSPLIADDEVIAQLPEAFLVSCENDILRDDSLLYKKRLEDQGVRVTW 369
+ LDV +PL+ADD + LP ++++C+ D+LRDD L+Y RL + GV+VT
Sbjct: 306 ELAKKYPGFLDVRAAPLLADDNKLRGLPLTYVITCQYDLLRDDGLMYVTRLRNTGVQVTH 365
Query: 370 YHLYDGFHGSIIFFDKKALSFPCSLKIVNAVVSYIK 405
H+ DGFHG+ F L S +++N + ++K
Sbjct: 366 NHVEDGFHGAFSF-----LGLKISHRLINQYIEWLK 396
>gi|68051721 arylacetamide deacetylase-like 1 isoform b [Homo
sapiens]
Length = 440
Score = 189 bits (479), Expect = 5e-48
Identities = 128/398 (32%), Positives = 197/398 (49%), Gaps = 23/398 (5%)
Query: 23 AVFEHFLTTDIPATLQHPAKLRFLHCIFLYLVTLGNIFEKLGICSMPKFIRFLHDSVRIK 82
A+ +++ +P ++ P KL L F + N+ LG+ + F+ S K
Sbjct: 45 ALAAYYVYIPLPGSVSDPWKLMLLDATFRGAQQVSNLIHYLGLSHHLLALNFIIVSFGKK 104
Query: 83 K---DPELVVTDLRFGTIPVRLFQPKAASSRP-RRGIIFYHGGATVFGS--LDCYHGLCN 136
++ VTD F + VR+F+ P +R +++ HGG S + Y LC
Sbjct: 105 SAWSSAQVKVTDTDFDGVEVRVFEGPPKPEEPLKRSVVYIHGGGWALASAKIRYYDELCT 164
Query: 137 YLARETESVLLMIGYRKLPDHHSPALFQDCMNASIHFLK--ALETYGVDPSRVVVCGESV 194
+A E +V++ I YR +P + P D + A+ +FLK L+ Y VDP R+ + G+S
Sbjct: 165 AMAEELNAVIVSIEYRLVPKVYFPEQIHDVVRATKYFLKPEVLQKYMVDPGRICISGDSA 224
Query: 195 GGAAVAAITQALVGRSDLP-RIRAQVLIYPVVQAFCLQLPSFQQNQNVPLLSRKFMVTSL 253
GG AA+ Q + L +++ Q LIYPV+QA PS+QQN N P+L R MV
Sbjct: 225 GGNLAAALGQQFTQDASLKNKLKLQALIYPVLQALDFNTPSYQQNVNTPILPRYVMVKYW 284
Query: 254 CNYLAIDLSWRDAILNGTCVPPDVW-----RKYEKWLSPDNIPKKFKNRGYQPWSPGPFN 308
+Y + + A++ DV R W S +P F + Y+P N
Sbjct: 285 VDYFKGNYDFVQAMIVNNHTSLDVEEAAAVRARLNWTSL--LPASF-TKNYKPVVQTTGN 341
Query: 309 EAAYLEAKHMLDVENSPLIADDEVIAQLPEAFLVSCENDILRDDSLLYKKRLEDQGVRVT 368
E +LD ++PLIAD V+ LP+ ++++CE+D+LRDD ++Y KRLE GV VT
Sbjct: 342 ARIVQELPQLLDARSAPLIADQAVLQLLPKTYILTCEHDVLRDDGIMYAKRLESAGVEVT 401
Query: 369 WYHLYDGFHGSIIFFDKKALSFPCSLKI-VNAVVSYIK 405
H DGFHG +IF S+P + + + SYIK
Sbjct: 402 LDHFEDGFHGCMIF-----TSWPTNFSVGIRTRNSYIK 434
>gi|226423947 arylacetamide deacetylase-like 1 isoform a [Homo
sapiens]
Length = 448
Score = 186 bits (472), Expect = 3e-47
Identities = 128/406 (31%), Positives = 196/406 (48%), Gaps = 31/406 (7%)
Query: 23 AVFEHFLTTDIPATLQHPAKLRFLHCIFLYLVTLGNIFEKLGICSMPKFIRFLHDSVRIK 82
A+ +++ +P ++ P KL L F + N+ LG+ + F+ S K
Sbjct: 45 ALAAYYVYIPLPGSVSDPWKLMLLDATFRGAQQVSNLIHYLGLSHHLLALNFIIVSFGKK 104
Query: 83 K---DPELVVTDLRFGTIPVRLFQPKAASSRP-RRGIIFYHGGATVFGSLDC-------- 130
++ VTD F + VR+F+ P +R +++ HGG S
Sbjct: 105 SAWSSAQVKVTDTDFDGVEVRVFEGPPKPEEPLKRSVVYIHGGGWALASASASWSPSDEI 164
Query: 131 --YHGLCNYLARETESVLLMIGYRKLPDHHSPALFQDCMNASIHFLK--ALETYGVDPSR 186
Y LC +A E +V++ I YR +P + P D + A+ +FLK L+ Y VDP R
Sbjct: 165 RYYDELCTAMAEELNAVIVSIEYRLVPKVYFPEQIHDVVRATKYFLKPEVLQKYMVDPGR 224
Query: 187 VVVCGESVGGAAVAAITQALVGRSDLP-RIRAQVLIYPVVQAFCLQLPSFQQNQNVPLLS 245
+ + G+S GG AA+ Q + L +++ Q LIYPV+QA PS+QQN N P+L
Sbjct: 225 ICISGDSAGGNLAAALGQQFTQDASLKNKLKLQALIYPVLQALDFNTPSYQQNVNTPILP 284
Query: 246 RKFMVTSLCNYLAIDLSWRDAILNGTCVPPDVW-----RKYEKWLSPDNIPKKFKNRGYQ 300
R MV +Y + + A++ DV R W S +P F + Y+
Sbjct: 285 RYVMVKYWVDYFKGNYDFVQAMIVNNHTSLDVEEAAAVRARLNWTSL--LPASF-TKNYK 341
Query: 301 PWSPGPFNEAAYLEAKHMLDVENSPLIADDEVIAQLPEAFLVSCENDILRDDSLLYKKRL 360
P N E +LD ++PLIAD V+ LP+ ++++CE+D+LRDD ++Y KRL
Sbjct: 342 PVVQTTGNARIVQELPQLLDARSAPLIADQAVLQLLPKTYILTCEHDVLRDDGIMYAKRL 401
Query: 361 EDQGVRVTWYHLYDGFHGSIIFFDKKALSFPCSLKI-VNAVVSYIK 405
E GV VT H DGFHG +IF S+P + + + SYIK
Sbjct: 402 ESAGVEVTLDHFEDGFHGCMIF-----TSWPTNFSVGIRTRNSYIK 442
>gi|206597554 arylacetamide deacetylase-like 2 [Homo sapiens]
Length = 401
Score = 169 bits (428), Expect = 4e-42
Identities = 118/383 (30%), Positives = 189/383 (49%), Gaps = 17/383 (4%)
Query: 10 LALPIFFLGVFVWAVFEHFLTTDIPATLQHPAKLRFLHCIFLYLVTLGNIFEKLGICSMP 69
+ L LG+ HF T +P ++ K+ L I FE + I
Sbjct: 1 MGLKALCLGLLCVLFVSHFYTP-MPDNIEESWKIMALDAIAKTCTFTAMCFENMRIMRYE 59
Query: 70 KFIRFLH--DSVRIKKDPELVVTDLRFGTIPVRLFQPKAASSRPRRGIIFYHGGATVFGS 127
+FI + D + D + VTD F IPVRL+ PK S RR +I++HGG FGS
Sbjct: 60 EFISMIFRLDYTQPLSDEYITVTDTTFVDIPVRLYLPKRKSETRRRAVIYFHGGGFCFGS 119
Query: 128 LD--CYHGLCNYLARETESVLLMIGYRKLPDHHSPALFQDCMNASIHFL--KALETYGVD 183
+ L + A ++V++ + YR P HH PA F+D + A FL K L YGVD
Sbjct: 120 SKQRAFDFLNRWTANTLDAVVVGVDYRLAPQHHFPAQFEDGLAAVKFFLLEKILTKYGVD 179
Query: 184 PSRVVVCGESVGGAAVAAITQALVGRSDLP-RIRAQVLIYPVVQAFCLQLPSFQQNQNVP 242
P+R+ + G+S GG A+TQ + +++ +I+ QVL+YP +Q LPS ++N++
Sbjct: 180 PTRICIAGDSSGGNLATAVTQQVQNDAEIKHKIKMQVLLYPGLQITDSYLPSHRENEHGI 239
Query: 243 LLSRKFMVTSLCNYLAIDLSWRDAILNGTCVPPDVWR--KYEKWLSPDNIPKKF-KNRGY 299
+L+R + + Y D + A+ +P + K+ W +P+K+ K+ Y
Sbjct: 240 VLTRDVAIKLVSLYFTKDEALPWAMRRNQHMPLESRHLFKFVNWSIL--LPEKYRKDYVY 297
Query: 300 QPWSPGPFNEAAYLEAKHMLDVENSPLIADDEVIAQLPEAFLVSCENDILRDDSLLYKKR 359
P + D PL+A+D + LP ++++C++D+LRDD L+Y R
Sbjct: 298 TE----PILGGLSYSLPGLTDSRALPLLANDSQLQNLPLTYILTCQHDLLRDDGLMYVTR 353
Query: 360 LEDQGVRVTWYHLYDGFHGSIIF 382
L + GV+V H+ DG HG++ F
Sbjct: 354 LRNVGVQVVHEHIEDGIHGALSF 376
>gi|226423952 arylacetamide deacetylase-like 1 isoform c [Homo
sapiens]
Length = 275
Score = 155 bits (392), Expect = 6e-38
Identities = 99/277 (35%), Positives = 146/277 (52%), Gaps = 17/277 (6%)
Query: 138 LARETESVLLMIGYRKLPDHHSPALFQDCMNASIHFLK--ALETYGVDPSRVVVCGESVG 195
+A E +V++ I YR +P + P D + A+ +FLK L+ Y VDP R+ + G+S G
Sbjct: 1 MAEELNAVIVSIEYRLVPKVYFPEQIHDVVRATKYFLKPEVLQKYMVDPGRICISGDSAG 60
Query: 196 GAAVAAITQALVGRSDLP-RIRAQVLIYPVVQAFCLQLPSFQQNQNVPLLSRKFMVTSLC 254
G AA+ Q + L +++ Q LIYPV+QA PS+QQN N P+L R MV
Sbjct: 61 GNLAAALGQQFTQDASLKNKLKLQALIYPVLQALDFNTPSYQQNVNTPILPRYVMVKYWV 120
Query: 255 NYLAIDLSWRDAILNGTCVPPDVW-----RKYEKWLSPDNIPKKFKNRGYQPWSPGPFNE 309
+Y + + A++ DV R W S +P F + Y+P N
Sbjct: 121 DYFKGNYDFVQAMIVNNHTSLDVEEAAAVRARLNWTSL--LPASF-TKNYKPVVQTTGNA 177
Query: 310 AAYLEAKHMLDVENSPLIADDEVIAQLPEAFLVSCENDILRDDSLLYKKRLEDQGVRVTW 369
E +LD ++PLIAD V+ LP+ ++++CE+D+LRDD ++Y KRLE GV VT
Sbjct: 178 RIVQELPQLLDARSAPLIADQAVLQLLPKTYILTCEHDVLRDDGIMYAKRLESAGVEVTL 237
Query: 370 YHLYDGFHGSIIFFDKKALSFPCSLKI-VNAVVSYIK 405
H DGFHG +IF S+P + + + SYIK
Sbjct: 238 DHFEDGFHGCMIF-----TSWPTNFSVGIRTRNSYIK 269
>gi|226423950 arylacetamide deacetylase-like 1 isoform c [Homo
sapiens]
Length = 275
Score = 155 bits (392), Expect = 6e-38
Identities = 99/277 (35%), Positives = 146/277 (52%), Gaps = 17/277 (6%)
Query: 138 LARETESVLLMIGYRKLPDHHSPALFQDCMNASIHFLK--ALETYGVDPSRVVVCGESVG 195
+A E +V++ I YR +P + P D + A+ +FLK L+ Y VDP R+ + G+S G
Sbjct: 1 MAEELNAVIVSIEYRLVPKVYFPEQIHDVVRATKYFLKPEVLQKYMVDPGRICISGDSAG 60
Query: 196 GAAVAAITQALVGRSDLP-RIRAQVLIYPVVQAFCLQLPSFQQNQNVPLLSRKFMVTSLC 254
G AA+ Q + L +++ Q LIYPV+QA PS+QQN N P+L R MV
Sbjct: 61 GNLAAALGQQFTQDASLKNKLKLQALIYPVLQALDFNTPSYQQNVNTPILPRYVMVKYWV 120
Query: 255 NYLAIDLSWRDAILNGTCVPPDVW-----RKYEKWLSPDNIPKKFKNRGYQPWSPGPFNE 309
+Y + + A++ DV R W S +P F + Y+P N
Sbjct: 121 DYFKGNYDFVQAMIVNNHTSLDVEEAAAVRARLNWTSL--LPASF-TKNYKPVVQTTGNA 177
Query: 310 AAYLEAKHMLDVENSPLIADDEVIAQLPEAFLVSCENDILRDDSLLYKKRLEDQGVRVTW 369
E +LD ++PLIAD V+ LP+ ++++CE+D+LRDD ++Y KRLE GV VT
Sbjct: 178 RIVQELPQLLDARSAPLIADQAVLQLLPKTYILTCEHDVLRDDGIMYAKRLESAGVEVTL 237
Query: 370 YHLYDGFHGSIIFFDKKALSFPCSLKI-VNAVVSYIK 405
H DGFHG +IF S+P + + + SYIK
Sbjct: 238 DHFEDGFHGCMIF-----TSWPTNFSVGIRTRNSYIK 269
>gi|21328446 hormone-sensitive lipase [Homo sapiens]
Length = 1076
Score = 40.8 bits (94), Expect = 0.002
Identities = 21/55 (38%), Positives = 32/55 (58%)
Query: 324 SPLIADDEVIAQLPEAFLVSCENDILRDDSLLYKKRLEDQGVRVTWYHLYDGFHG 378
SPL+A D ++ LP +V+C D + DDS++ +RL + G VT + D HG
Sbjct: 971 SPLLAPDSMLKSLPPVHIVACALDPMLDDSVMLARRLRNLGQPVTLRVVEDLPHG 1025
Score = 40.0 bits (92), Expect = 0.004
Identities = 29/129 (22%), Positives = 55/129 (42%), Gaps = 1/129 (0%)
Query: 69 PKFIRFLHDSVRIKKDPELVVTDLRF-GTIPVRLFQPKAASSRPRRGIIFYHGGATVFGS 127
P +R + +R +D E + + ++ G + L+ + R R I+ +HGG V +
Sbjct: 600 PVLVRLISYDLREGQDSEELSSLIKSNGQRSLELWPRPQQAPRSRSLIVHFHGGGFVAQT 659
Query: 128 LDCYHGLCNYLARETESVLLMIGYRKLPDHHSPALFQDCMNASIHFLKALETYGVDPSRV 187
+ A+E + ++ I Y P+ P ++C A +K G R+
Sbjct: 660 SRSHEPYLKSWAQELGAPIISIDYSLAPEAPFPRALEECFFAYCWAIKHCALLGSTGERI 719
Query: 188 VVCGESVGG 196
+ G+S GG
Sbjct: 720 CLAGDSAGG 728
>gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens]
Length = 607
Score = 40.0 bits (92), Expect = 0.004
Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 11/97 (11%)
Query: 115 IIFYHGGATVFGSLDCYHGLCNYLARETESVLLMIGYR-------KLPDHHSPAL--FQD 165
+++ HGGA VFG Y G + LA V+++I YR D H+ + D
Sbjct: 207 MVWIHGGALVFGMASLYDG--SMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLD 264
Query: 166 CMNASIHFLKALETYGVDPSRVVVCGESVGGAAVAAI 202
+ A + + +G +P RV + GES GG +V+++
Sbjct: 265 QVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSL 301
>gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens]
Length = 623
Score = 40.0 bits (92), Expect = 0.004
Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 11/97 (11%)
Query: 115 IIFYHGGATVFGSLDCYHGLCNYLARETESVLLMIGYR-------KLPDHHSPAL--FQD 165
+++ HGGA VFG Y G + LA V+++I YR D H+ + D
Sbjct: 207 MVWIHGGALVFGMASLYDG--SMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLD 264
Query: 166 CMNASIHFLKALETYGVDPSRVVVCGESVGGAAVAAI 202
+ A + + +G +P RV + GES GG +V+++
Sbjct: 265 QVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSL 301
>gi|219521907 carboxylesterase 7 isoform 1 [Homo sapiens]
Length = 575
Score = 40.0 bits (92), Expect = 0.004
Identities = 28/97 (28%), Positives = 50/97 (51%), Gaps = 11/97 (11%)
Query: 115 IIFYHGGATVFGSLDCYHGLCNYLARETESVLLMIGYR-------KLPDHHSPA--LFQD 165
++++ GGA GS + G + LA + +++++ YR D H+P F+D
Sbjct: 141 LVWFPGGAFKTGSASIFDG--SALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKD 198
Query: 166 CMNASIHFLKALETYGVDPSRVVVCGESVGGAAVAAI 202
+ A K +E +G DPS V + GES G +V+++
Sbjct: 199 QVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSL 235
>gi|21450749 carboxylesterase 7 isoform 2 [Homo sapiens]
Length = 525
Score = 40.0 bits (92), Expect = 0.004
Identities = 28/97 (28%), Positives = 50/97 (51%), Gaps = 11/97 (11%)
Query: 115 IIFYHGGATVFGSLDCYHGLCNYLARETESVLLMIGYR-------KLPDHHSPA--LFQD 165
++++ GGA GS + G + LA + +++++ YR D H+P F+D
Sbjct: 141 LVWFPGGAFKTGSASIFDG--SALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKD 198
Query: 166 CMNASIHFLKALETYGVDPSRVVVCGESVGGAAVAAI 202
+ A K +E +G DPS V + GES G +V+++
Sbjct: 199 QVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSL 235
>gi|169216018 PREDICTED: similar to hCG40360 [Homo sapiens]
Length = 327
Score = 39.3 bits (90), Expect = 0.006
Identities = 29/92 (31%), Positives = 47/92 (51%), Gaps = 11/92 (11%)
Query: 120 GGATVFGSLDCYHGLCNYLARETESVLLMIGYR-------KLPDHHSPA--LFQDCMNAS 170
GGA GS + G + LA + +++++ YR D H+P F+D + A
Sbjct: 20 GGAFETGSASIFDG--SSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQVAAL 77
Query: 171 IHFLKALETYGVDPSRVVVCGESVGGAAVAAI 202
K +E +G DPS V + GESVG +V+++
Sbjct: 78 SWVQKNIEFFGGDPSSVTIFGESVGAISVSSL 109
>gi|169215613 PREDICTED: similar to hCG40360 [Homo sapiens]
Length = 327
Score = 39.3 bits (90), Expect = 0.006
Identities = 29/92 (31%), Positives = 47/92 (51%), Gaps = 11/92 (11%)
Query: 120 GGATVFGSLDCYHGLCNYLARETESVLLMIGYR-------KLPDHHSPA--LFQDCMNAS 170
GGA GS + G + LA + +++++ YR D H+P F+D + A
Sbjct: 20 GGAFETGSASIFDG--SSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQVAAL 77
Query: 171 IHFLKALETYGVDPSRVVVCGESVGGAAVAAI 202
K +E +G DPS V + GESVG +V+++
Sbjct: 78 SWVQKNIEFFGGDPSSVTIFGESVGAISVSSL 109
>gi|33563374 carboxylesterase 3 [Homo sapiens]
Length = 571
Score = 35.4 bits (80), Expect = 0.093
Identities = 30/106 (28%), Positives = 50/106 (47%), Gaps = 13/106 (12%)
Query: 106 AASSRPRRGIIFYHGGATVFGSLDCYHGLCNYLARETESVLLMIGYR-------KLPDHH 158
A S RP +++ HGGA + G+ Y G + LA + V++ + YR D H
Sbjct: 137 AGSGRPV--MVWVHGGALITGAATSYDG--SALAAYGDVVVVTVQYRLGVLGFFSTGDEH 192
Query: 159 SPAL--FQDCMNASIHFLKALETYGVDPSRVVVCGESVGGAAVAAI 202
+P F D + A + + +G D + V V G S GG+ ++ +
Sbjct: 193 APGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGL 238
>gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens]
Length = 568
Score = 35.0 bits (79), Expect = 0.12
Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 11/97 (11%)
Query: 115 IIFYHGGATVFGSLDCYHGLCNYLARETESVLLMIGYR-------KLPDHHSPALFQ--D 165
+++ HGG + G+ Y GL LA V++ I YR D HS + D
Sbjct: 137 MVWIHGGGLMVGAASTYDGLA--LAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLD 194
Query: 166 CMNASIHFLKALETYGVDPSRVVVCGESVGGAAVAAI 202
+ A + ++G +P V + GES GG +V+ +
Sbjct: 195 QVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVL 231
>gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens]
Length = 567
Score = 35.0 bits (79), Expect = 0.12
Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 11/97 (11%)
Query: 115 IIFYHGGATVFGSLDCYHGLCNYLARETESVLLMIGYR-------KLPDHHSPALFQ--D 165
+++ HGG + G+ Y GL LA V++ I YR D HS + D
Sbjct: 136 MVWIHGGGLMVGAASTYDGLA--LAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLD 193
Query: 166 CMNASIHFLKALETYGVDPSRVVVCGESVGGAAVAAI 202
+ A + ++G +P V + GES GG +V+ +
Sbjct: 194 QVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVL 230
>gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens]
Length = 566
Score = 35.0 bits (79), Expect = 0.12
Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 11/97 (11%)
Query: 115 IIFYHGGATVFGSLDCYHGLCNYLARETESVLLMIGYR-------KLPDHHSPALFQ--D 165
+++ HGG + G+ Y GL LA V++ I YR D HS + D
Sbjct: 136 MVWIHGGGLMVGAASTYDGLA--LAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLD 193
Query: 166 CMNASIHFLKALETYGVDPSRVVVCGESVGGAAVAAI 202
+ A + ++G +P V + GES GG +V+ +
Sbjct: 194 QVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVL 230
>gi|148536848 carboxyl ester lipase precursor [Homo sapiens]
Length = 756
Score = 33.5 bits (75), Expect = 0.36
Identities = 32/116 (27%), Positives = 52/116 (44%), Gaps = 15/116 (12%)
Query: 103 QPKAASSRPRRGIIFYHGGATVFGSLDCYHGLCNYL------ARETESVLLMIGYRKLP- 155
Q + SR +I+ +GGA + GS + L NYL A +++ YR P
Sbjct: 112 QGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPL 171
Query: 156 ------DHHSPALF--QDCMNASIHFLKALETYGVDPSRVVVCGESVGGAAVAAIT 203
D + P + +D A + + +G DP+ + + GES GGA+V+ T
Sbjct: 172 GFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQT 227
>gi|115529439 carboxylesterase 8 (putative) [Homo sapiens]
Length = 491
Score = 32.7 bits (73), Expect = 0.61
Identities = 26/114 (22%), Positives = 52/114 (45%), Gaps = 12/114 (10%)
Query: 99 VRLFQPKAASSRPRRGI-IFYHGGATVFGSLDCYHGLCNYLARETESVLLMI-------G 150
+ ++ P A P+ + +++ GGA + G+ Y G + LA + VL+ + G
Sbjct: 119 LNVYAPARAPGDPQLPVMVWFPGGAFIVGAASSYEG--SDLAAREKVVLVFLQHRLGIFG 176
Query: 151 YRKLPDHHSPALFQ--DCMNASIHFLKALETYGVDPSRVVVCGESVGGAAVAAI 202
+ D H+ + D M A + + +G DP V + G+S G +++ +
Sbjct: 177 FLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGL 230
>gi|239752162 PREDICTED: similar to hCG40360 [Homo sapiens]
Length = 131
Score = 32.3 bits (72), Expect = 0.79
Identities = 25/88 (28%), Positives = 43/88 (48%), Gaps = 11/88 (12%)
Query: 111 PRRGIIFYHGGATVFGSLDCYHGLCNYLARETESVLLMIGYR-------KLPDHHSPA-- 161
P R ++++ GGA GS + G + LA + +++++ YR D H+P
Sbjct: 17 PPRVLLWFPGGAFETGSASIFDG--SSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNW 74
Query: 162 LFQDCMNASIHFLKALETYGVDPSRVVV 189
F+D + A K +E +G DPS V +
Sbjct: 75 AFKDQVAALSWVQKNIEFFGGDPSSVTI 102
>gi|7662470 neuroligin 1 [Homo sapiens]
Length = 823
Score = 31.6 bits (70), Expect = 1.3
Identities = 25/105 (23%), Positives = 47/105 (44%), Gaps = 11/105 (10%)
Query: 108 SSRPRRGIIFYHGGATVFGSLDCYHGLCNYLARETESVLLMIGYR-------KLPDHHSP 160
S P+ +++ HGG+ + G+ + Y G + LA +++ + YR D +
Sbjct: 169 SGGPKPVMVYIHGGSYMEGTGNLYDG--SVLASYGNVIVITVNYRLGVLGFLSTGDQAAK 226
Query: 161 ALFQ--DCMNASIHFLKALETYGVDPSRVVVCGESVGGAAVAAIT 203
+ D + A + + +G DP R+ V G GG+ V +T
Sbjct: 227 GNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLT 271
>gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo
sapiens]
Length = 614
Score = 30.0 bits (66), Expect = 3.9
Identities = 28/113 (24%), Positives = 48/113 (42%), Gaps = 14/113 (12%)
Query: 99 VRLFQPKAASSRPRRGIIFYHGGATVFG--SLDCYHGLCNYLARETESVLLMIGYR---- 152
+ ++ P + P +++ +GG G SLD Y G +L + +VL+ + YR
Sbjct: 130 LNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDG--RFLVQAERTVLVSMNYRVGAF 187
Query: 153 ---KLPDHHSPALFQDCMNASIHFLKALET---YGVDPSRVVVCGESVGGAAV 199
LP ++ + E +G DP+ V + GES G A+V
Sbjct: 188 GFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV 240
>gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo
sapiens]
Length = 617
Score = 30.0 bits (66), Expect = 3.9
Identities = 28/113 (24%), Positives = 48/113 (42%), Gaps = 14/113 (12%)
Query: 99 VRLFQPKAASSRPRRGIIFYHGGATVFG--SLDCYHGLCNYLARETESVLLMIGYR---- 152
+ ++ P + P +++ +GG G SLD Y G +L + +VL+ + YR
Sbjct: 130 LNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDG--RFLVQAERTVLVSMNYRVGAF 187
Query: 153 ---KLPDHHSPALFQDCMNASIHFLKALET---YGVDPSRVVVCGESVGGAAV 199
LP ++ + E +G DP+ V + GES G A+V
Sbjct: 188 GFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV 240
>gi|23308553 spermatogenesis associated 13 [Homo sapiens]
Length = 652
Score = 30.0 bits (66), Expect = 3.9
Identities = 13/21 (61%), Positives = 16/21 (76%)
Query: 341 LVSCENDILRDDSLLYKKRLE 361
LVSC+ D+LR D L YK RL+
Sbjct: 483 LVSCKKDLLRRDMLYYKGRLD 503
>gi|15011979 Rho guanine nucleotide exchange factor 4 isoform a
[Homo sapiens]
Length = 690
Score = 30.0 bits (66), Expect = 3.9
Identities = 13/27 (48%), Positives = 18/27 (66%)
Query: 341 LVSCENDILRDDSLLYKKRLEDQGVRV 367
L+ C+ D+LR D L YK RL+ G+ V
Sbjct: 528 LIYCKKDLLRRDVLYYKGRLDMDGLEV 554
>gi|15011981 Rho guanine nucleotide exchange factor 4 isoform b
[Homo sapiens]
Length = 670
Score = 30.0 bits (66), Expect = 3.9
Identities = 13/27 (48%), Positives = 18/27 (66%)
Query: 341 LVSCENDILRDDSLLYKKRLEDQGVRV 367
L+ C+ D+LR D L YK RL+ G+ V
Sbjct: 528 LIYCKKDLLRRDVLYYKGRLDMDGLEV 554
>gi|194272176 phospholipase D1 isoform b [Homo sapiens]
Length = 1036
Score = 29.3 bits (64), Expect = 6.7
Identities = 16/48 (33%), Positives = 24/48 (50%)
Query: 343 SCENDILRDDSLLYKKRLEDQGVRVTWYHLYDGFHGSIIFFDKKALSF 390
S EN I + L +K+LED ++ +Y +H + F D LSF
Sbjct: 166 SSENMIREEQFLGRRKQLEDYLTKILKMPMYRNYHATTEFLDISQLSF 213
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.143 0.453
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,716,623
Number of Sequences: 37866
Number of extensions: 700115
Number of successful extensions: 1929
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 1881
Number of HSP's gapped (non-prelim): 34
length of query: 407
length of database: 18,247,518
effective HSP length: 105
effective length of query: 302
effective length of database: 14,271,588
effective search space: 4310019576
effective search space used: 4310019576
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.