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Search of human proteins with 61743940
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|61743940 G-protein coupled receptor 110 isoform 1 [Homo
sapiens]
(910 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|61743940 G-protein coupled receptor 110 isoform 1 [Homo sapiens] 1826 0.0
gi|61743938 G-protein coupled receptor 110 isoform 2 [Homo sapiens] 427 e-119
gi|134288847 G-protein coupled receptor 111 [Homo sapiens] 419 e-117
gi|148719671 G-protein coupled receptor 116 [Homo sapiens] 405 e-113
gi|148719673 G-protein coupled receptor 116 [Homo sapiens] 405 e-113
gi|116517328 G-protein coupled receptor 115 [Homo sapiens] 399 e-111
gi|223556012 G-protein coupled receptor 113 isoform 1 [Homo sapi... 268 1e-71
gi|223556014 G-protein coupled receptor 113 isoform 2 [Homo sapi... 268 1e-71
gi|141802362 G-protein coupled receptor 113 isoform 3 [Homo sapi... 268 1e-71
gi|163792198 latrophilin 3 precursor [Homo sapiens] 154 3e-37
gi|45433552 G protein-coupled receptor 133 [Homo sapiens] 145 1e-34
gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [... 139 1e-32
gi|133930786 egf-like module-containing mucin-like receptor 3 [H... 139 1e-32
gi|6912464 latrophilin 2 precursor [Homo sapiens] 137 6e-32
gi|148806925 EGF, latrophilin and seven transmembrane domain con... 134 3e-31
gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens] 134 5e-31
gi|4502359 brain-specific angiogenesis inhibitor 3 [Homo sapiens] 130 7e-30
gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens] 125 1e-28
gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens] 125 1e-28
gi|74048357 G protein-coupled receptor 126 alpha 1 precursor [Ho... 125 2e-28
gi|50355941 G protein-coupled receptor 126 beta 1 precursor [Hom... 125 2e-28
gi|74048422 G protein-coupled receptor 126 alpha 2 precursor [Ho... 125 2e-28
gi|74048403 G protein-coupled receptor 126 beta 2 precursor [Hom... 125 2e-28
gi|59710093 G-protein coupled receptor 112 [Homo sapiens] 125 2e-28
gi|23397681 egf-like module containing, mucin-like, hormone rece... 123 9e-28
gi|23397693 egf-like module containing, mucin-like, hormone rece... 123 9e-28
gi|23397691 egf-like module containing, mucin-like, hormone rece... 123 9e-28
gi|23397689 egf-like module containing, mucin-like, hormone rece... 123 9e-28
gi|23397687 egf-like module containing, mucin-like, hormone rece... 123 9e-28
gi|23397685 egf-like module containing, mucin-like, hormone rece... 123 9e-28
>gi|61743940 G-protein coupled receptor 110 isoform 1 [Homo sapiens]
Length = 910
Score = 1826 bits (4729), Expect = 0.0
Identities = 910/910 (100%), Positives = 910/910 (100%)
Query: 1 MKVGVLWLISFFTFTDGHGGFLGKNDGIKTKKELIVNKKKHLGPVEEYQLLLQVTYRDSK 60
MKVGVLWLISFFTFTDGHGGFLGKNDGIKTKKELIVNKKKHLGPVEEYQLLLQVTYRDSK
Sbjct: 1 MKVGVLWLISFFTFTDGHGGFLGKNDGIKTKKELIVNKKKHLGPVEEYQLLLQVTYRDSK 60
Query: 61 EKRDLRNFLKLLKPPLLWSHGLIRIIRAKATTDCNSLNGVLQCTCEDSYTWFPPSCLDPQ 120
EKRDLRNFLKLLKPPLLWSHGLIRIIRAKATTDCNSLNGVLQCTCEDSYTWFPPSCLDPQ
Sbjct: 61 EKRDLRNFLKLLKPPLLWSHGLIRIIRAKATTDCNSLNGVLQCTCEDSYTWFPPSCLDPQ 120
Query: 121 NCYLHTAGALPSCECHLNNLSQSVNFCERTKIWGTFKINERFTNDLLNSSSAIYSKYANG 180
NCYLHTAGALPSCECHLNNLSQSVNFCERTKIWGTFKINERFTNDLLNSSSAIYSKYANG
Sbjct: 121 NCYLHTAGALPSCECHLNNLSQSVNFCERTKIWGTFKINERFTNDLLNSSSAIYSKYANG 180
Query: 181 IEIQLKKAYERIQGFESVQVTQFRNGSIVAGYEVVGSSSASELLSAIEHVAEKAKTALHK 240
IEIQLKKAYERIQGFESVQVTQFRNGSIVAGYEVVGSSSASELLSAIEHVAEKAKTALHK
Sbjct: 181 IEIQLKKAYERIQGFESVQVTQFRNGSIVAGYEVVGSSSASELLSAIEHVAEKAKTALHK 240
Query: 241 LFPLEDGSFRVFGKAQCNDIVFGFGSKDDEYTLPCSSGYRGNITAKCESSGWQVIRETCV 300
LFPLEDGSFRVFGKAQCNDIVFGFGSKDDEYTLPCSSGYRGNITAKCESSGWQVIRETCV
Sbjct: 241 LFPLEDGSFRVFGKAQCNDIVFGFGSKDDEYTLPCSSGYRGNITAKCESSGWQVIRETCV 300
Query: 301 LSLLEELNKNFSMIVGNATEAAVSSFVQNLSVIIRQNPSTTVGNLASVVSILSNISSLSL 360
LSLLEELNKNFSMIVGNATEAAVSSFVQNLSVIIRQNPSTTVGNLASVVSILSNISSLSL
Sbjct: 301 LSLLEELNKNFSMIVGNATEAAVSSFVQNLSVIIRQNPSTTVGNLASVVSILSNISSLSL 360
Query: 361 ASHFRVSNSTMEDVISIADNILNSASVTNWTVLLREEKYASSRLLETLENISTLVPPTAL 420
ASHFRVSNSTMEDVISIADNILNSASVTNWTVLLREEKYASSRLLETLENISTLVPPTAL
Sbjct: 361 ASHFRVSNSTMEDVISIADNILNSASVTNWTVLLREEKYASSRLLETLENISTLVPPTAL 420
Query: 421 PLNFSRKFIDWKGIPVNKSQLKRGYSYQIKMCPQNTSIPIRGRVLIGSDQFQRSLPETII 480
PLNFSRKFIDWKGIPVNKSQLKRGYSYQIKMCPQNTSIPIRGRVLIGSDQFQRSLPETII
Sbjct: 421 PLNFSRKFIDWKGIPVNKSQLKRGYSYQIKMCPQNTSIPIRGRVLIGSDQFQRSLPETII 480
Query: 481 SMASLTLGNILPVSKNGNAQVNGPVISTVIQNYSINEVFLFFSKIESNLSQPHCVFWDFS 540
SMASLTLGNILPVSKNGNAQVNGPVISTVIQNYSINEVFLFFSKIESNLSQPHCVFWDFS
Sbjct: 481 SMASLTLGNILPVSKNGNAQVNGPVISTVIQNYSINEVFLFFSKIESNLSQPHCVFWDFS 540
Query: 541 HLQWNDAGCHLVNETQDIVTCQCTHLTSFSILMSPFVPSTIFPVVKWITYVGLGISIGSL 600
HLQWNDAGCHLVNETQDIVTCQCTHLTSFSILMSPFVPSTIFPVVKWITYVGLGISIGSL
Sbjct: 541 HLQWNDAGCHLVNETQDIVTCQCTHLTSFSILMSPFVPSTIFPVVKWITYVGLGISIGSL 600
Query: 601 ILCLIIEALFWKQIKKSQTSHTRRICMVNIALSLLIADVWFIVGATVDTTVNPSGVCTAA 660
ILCLIIEALFWKQIKKSQTSHTRRICMVNIALSLLIADVWFIVGATVDTTVNPSGVCTAA
Sbjct: 601 ILCLIIEALFWKQIKKSQTSHTRRICMVNIALSLLIADVWFIVGATVDTTVNPSGVCTAA 660
Query: 661 VFFTHFFYLSLFFWMLMLGILLAYRIILVFHHMAQHLMMAVGFCLGYGCPLIISVITIAV 720
VFFTHFFYLSLFFWMLMLGILLAYRIILVFHHMAQHLMMAVGFCLGYGCPLIISVITIAV
Sbjct: 661 VFFTHFFYLSLFFWMLMLGILLAYRIILVFHHMAQHLMMAVGFCLGYGCPLIISVITIAV 720
Query: 721 TQPSNTYKRKDVCWLNWSNGSKPLLAFVVPALAIVAVNFVVVLLVLTKLWRPTVGERLSR 780
TQPSNTYKRKDVCWLNWSNGSKPLLAFVVPALAIVAVNFVVVLLVLTKLWRPTVGERLSR
Sbjct: 721 TQPSNTYKRKDVCWLNWSNGSKPLLAFVVPALAIVAVNFVVVLLVLTKLWRPTVGERLSR 780
Query: 781 DDKATIIRVGKSLLILTPLLGLTWGFGIGTIVDSQNLAWHVIFALLNAFQGFFILCFGIL 840
DDKATIIRVGKSLLILTPLLGLTWGFGIGTIVDSQNLAWHVIFALLNAFQGFFILCFGIL
Sbjct: 781 DDKATIIRVGKSLLILTPLLGLTWGFGIGTIVDSQNLAWHVIFALLNAFQGFFILCFGIL 840
Query: 841 LDSKLRQLLFNKLSALSSWKQTEKQNSSDLSAKPKFSKPFNPLQNKGHYAFSHTGDSSDN 900
LDSKLRQLLFNKLSALSSWKQTEKQNSSDLSAKPKFSKPFNPLQNKGHYAFSHTGDSSDN
Sbjct: 841 LDSKLRQLLFNKLSALSSWKQTEKQNSSDLSAKPKFSKPFNPLQNKGHYAFSHTGDSSDN 900
Query: 901 IMLTQFVSNE 910
IMLTQFVSNE
Sbjct: 901 IMLTQFVSNE 910
>gi|61743938 G-protein coupled receptor 110 isoform 2 [Homo sapiens]
Length = 218
Score = 427 bits (1097), Expect = e-119
Identities = 204/204 (100%), Positives = 204/204 (100%)
Query: 1 MKVGVLWLISFFTFTDGHGGFLGKNDGIKTKKELIVNKKKHLGPVEEYQLLLQVTYRDSK 60
MKVGVLWLISFFTFTDGHGGFLGKNDGIKTKKELIVNKKKHLGPVEEYQLLLQVTYRDSK
Sbjct: 1 MKVGVLWLISFFTFTDGHGGFLGKNDGIKTKKELIVNKKKHLGPVEEYQLLLQVTYRDSK 60
Query: 61 EKRDLRNFLKLLKPPLLWSHGLIRIIRAKATTDCNSLNGVLQCTCEDSYTWFPPSCLDPQ 120
EKRDLRNFLKLLKPPLLWSHGLIRIIRAKATTDCNSLNGVLQCTCEDSYTWFPPSCLDPQ
Sbjct: 61 EKRDLRNFLKLLKPPLLWSHGLIRIIRAKATTDCNSLNGVLQCTCEDSYTWFPPSCLDPQ 120
Query: 121 NCYLHTAGALPSCECHLNNLSQSVNFCERTKIWGTFKINERFTNDLLNSSSAIYSKYANG 180
NCYLHTAGALPSCECHLNNLSQSVNFCERTKIWGTFKINERFTNDLLNSSSAIYSKYANG
Sbjct: 121 NCYLHTAGALPSCECHLNNLSQSVNFCERTKIWGTFKINERFTNDLLNSSSAIYSKYANG 180
Query: 181 IEIQLKKAYERIQGFESVQVTQFR 204
IEIQLKKAYERIQGFESVQVTQFR
Sbjct: 181 IEIQLKKAYERIQGFESVQVTQFR 204
>gi|134288847 G-protein coupled receptor 111 [Homo sapiens]
Length = 642
Score = 419 bits (1078), Expect = e-117
Identities = 237/601 (39%), Positives = 361/601 (60%), Gaps = 35/601 (5%)
Query: 272 TLPCSSGYRGNITAKCESSGWQVIRETC----VLSLLEELNK---------NFSMIVGNA 318
T PC +GN+ C W I +TC L++ EE ++ S+ G +
Sbjct: 52 TQPCPPDTQGNMGFSCRQKTWHKITDTCQTLNALNIFEEDSRLVQPFEDNIKISVYTGKS 111
Query: 319 ---TEAAVSSFVQNLSVIIR--QNPSTTVGNLASVVSILSNISSLSLASHFRVSNSTMED 373
T+ + +LS +IR Q GN+A +V +L NIS+ A V + M+
Sbjct: 112 ETITDMLLQKCPTDLSCVIRNIQQSPWIPGNIAVIVQLLHNIST---AIWTGVDEAKMQS 168
Query: 374 VISIADNILNSASVTNWTVLLREEKYASSRLLETLENISTLVPPTALPLNFSRKFIDWKG 433
+IA++ILNS S++NWT + ++ +S LL ++ + + + P++ S FI G
Sbjct: 169 YSTIANHILNSKSISNWTFI--PDRNSSYILLHSVNSFARRLFIDKHPVDISDVFIHTMG 226
Query: 434 IPVNKSQLKRGYSYQIKMCPQNTSIPIRGRVLIGSDQFQR-SLPETIISMASLTLGNILP 492
++ + + +++ +++ +TS + GRVLI D+ ++ P +IS+A T+G IL
Sbjct: 227 TTISGDNIGKNFTFSMRI--NDTSNEVTGRVLISRDELRKVPSPSQVISIAFPTIGAILE 284
Query: 493 VSKNGNAQVNGPVISTVIQNYSINEVFLFFSKI-ESNLSQPHCVFWDFSHLQWNDAGCHL 551
S N VNG V+S ++ + + L F KI +S + CV W +W+ C +
Sbjct: 285 ASLLENVTVNGLVLSAILPK-ELKRISLIFEKISKSEERRTQCVGWHSVENRWDQQACKM 343
Query: 552 VNETQDIVTCQCTH---LTSFSILMSPFVPSTIFPVVKWITYVGLGISIGSLILCLIIEA 608
+ E C+C TSFSILMSP + ++ ++ +ITYVGLGISI SLILCL IE
Sbjct: 344 IQENSQQAVCKCRPSKLFTSFSILMSPHILESL--ILTYITYVGLGISICSLILCLSIEV 401
Query: 609 LFWKQIKKSQTSHTRRICMVNIALSLLIADVWFIVGATVDTTVNPSGVCTAAVFFTHFFY 668
L W Q+ K++ ++ R +C+VNIA +LL+ADVWFIV + + + C AA FF HFFY
Sbjct: 402 LVWSQVTKTEITYLRHVCIVNIAATLLMADVWFIVASFLSGPITHHKGCVAATFFVHFFY 461
Query: 669 LSLFFWMLMLGILLAYRIILVFHHMAQHLMMAVGFCLGYGCPLIISVITIAVTQPSNTYK 728
LS+FFWML +L+ Y I++VFH + + +++A F +GYGCPL I+ IT+A T+P Y
Sbjct: 462 LSVFFWMLAKALLILYGIMIVFHTLPKSVLVASLFSVGYGCPLAIAAITVAATEPGKGYL 521
Query: 729 RKDVCWLNWSNGSKPLLAFVVPALAIVAVNFVVVLLVLTKLWRPTVGERLSRDDKATIIR 788
R ++CWLNW + +K LLAFV+PALAIV VN + V LV+ K R +G + ++ +A I+R
Sbjct: 522 RPEICWLNW-DMTKALLAFVIPALAIVVVNLITVTLVIVKTQRAAIGNSMFQEVRA-IVR 579
Query: 789 VGKSLLILTPLLGLTWGFGIGTIVDSQNLAWHVIFALLNAFQGFFILCFGILLDSKLRQL 848
+ K++ ILTPLLGLTWGFG+ T++D ++LA+H+IF+LLNAFQGFFIL FG +LD K+R+
Sbjct: 580 ISKNIAILTPLLGLTWGFGVATVIDDRSLAFHIIFSLLNAFQGFFILVFGTILDPKIREA 639
Query: 849 L 849
L
Sbjct: 640 L 640
>gi|148719671 G-protein coupled receptor 116 [Homo sapiens]
Length = 1346
Score = 405 bits (1041), Expect = e-113
Identities = 240/665 (36%), Positives = 373/665 (56%), Gaps = 38/665 (5%)
Query: 257 CNDIVFGFGSKDDEYTLPC---------SSGYRGNITAKCESSGWQVIRETCVLSLLEEL 307
C D V G G C S G IT KC S W+ R C+ + + L
Sbjct: 669 CQDPVIGVGEPGKVIQKLCRFSNVPSSPESPIGGTITYKCVGSQWEEKRNDCISAPINSL 728
Query: 308 NKNFSMIVGNATE-AAVSSFVQNLSVII---RQNPSTTVGNLASVVSILSNISSLSLASH 363
+ ++ + ++ + +++++LS+ I S++ G+L ++++IL +S++
Sbjct: 729 LQMAKALIKSPSQDEMLPTYLKDLSISIDKAEHEISSSPGSLGAIINILDLLSTVPT--- 785
Query: 364 FRVSNSTMEDVISIADNILNSASVTNWTVLLREEKYASSRLLETLENIS-TLVPPTALPL 422
+V++ M V+S + IL + W VL ++ SS+LL ++E S L + PL
Sbjct: 786 -QVNSEMMTHVLSTVNVILGKPVLNTWKVLQQQWTNQSSQLLHSVERFSQALQSGDSPPL 844
Query: 423 NFSRKFIDWKGIPVNKSQLKRGYSYQIKMCPQNTSIPIRGRVLIGSDQFQRSLPET-IIS 481
+FS+ + + + S + +YQ + + G V+I + ++ I++
Sbjct: 845 SFSQTNVQMSSMVIKSSHPE---TYQQRFV--FPYFDLWGNVVIDKSYLENLQSDSSIVT 899
Query: 482 MASLTLGNILPVSKNGNAQVNGPVISTVIQNYSIN--EVFLFFSKIESNLSQPHCVFWDF 539
MA TL IL N V++T + + + + + F + + CVFW+F
Sbjct: 900 MAFPTLQAILAQDIQENNFAESLVMTTTVSHNTTMPFRISMTFKNNSPSGGETKCVFWNF 959
Query: 540 SHLQ----WNDAGCHLVNETQDIVTCQCTHLTSFSILMSPFVP---STIFPVVKWITYVG 592
W+ +GC++ D VTC C HLTSFSILMSP P S + ++ I+YVG
Sbjct: 960 RLANNTGGWDSSGCYVEEGDGDNVTCICDHLTSFSILMSPDSPDPSSLLGILLDIISYVG 1019
Query: 593 LGISIGSLILCLIIEALFWKQIKKSQTSHTRRICMVNIALSLLIADVWFIVGATVDTT-- 650
+G SI SL CL++EA+ WK + K++TS+ R C+VNIA SLL+A+ WFIV A +
Sbjct: 1020 VGFSILSLAACLVVEAVVWKSVTKNRTSYMRHTCIVNIAASLLVANTWFIVVAAIQDNRY 1079
Query: 651 VNPSGVCTAAVFFTHFFYLSLFFWMLMLGILLAYRIILVFHHMAQHLMMAVGFCLGYGCP 710
+ C AA FF HFFYLS+FFWML LG++L YR++ + H ++ A+ FCLGYGCP
Sbjct: 1080 ILCKTACVAATFFIHFFYLSVFFWMLTLGLMLFYRLVFILHETSRSTQKAIAFCLGYGCP 1139
Query: 711 LIISVITIAVTQPSNTYKRKDVCWLNWSNGSKPLLAFVVPALAIVAVNFVVVLLVLTKLW 770
L ISVIT+ TQP Y RK+VCWLNW + +K LLAF +PAL IV VN + ++V+TK+
Sbjct: 1140 LAISVITLGATQPREVYTRKNVCWLNWED-TKALLAFAIPALIIVVVNITITIVVITKIL 1198
Query: 771 RPTVGERLSRDDKATIIRVGKSLLILTPLLGLTWGFGIGTIVDSQNLAWHVIFALLNAFQ 830
RP++G++ + +K+++ ++ KS+ +LTPLLGLTWGFG+ T+ NL +H+IFA+LN FQ
Sbjct: 1199 RPSIGDKPCKQEKSSLFQISKSIGVLTPLLGLTWGFGLTTVFPGTNLVFHIIFAILNVFQ 1258
Query: 831 GFFILCFGILLDSKLRQLLFNKLSALSSWKQTEKQNSSDLSAKPKFSKPFNPLQNKGHYA 890
G FIL FG L D K+++ L NK S LS W +++S S+ P FS +P+ + +
Sbjct: 1259 GLFILLFGCLWDLKVQEALLNKFS-LSRWSSQHSKSTSLGSSTPVFSMS-SPISRRFNNL 1316
Query: 891 FSHTG 895
F TG
Sbjct: 1317 FGKTG 1321
Score = 84.7 bits (208), Expect = 3e-16
Identities = 60/214 (28%), Positives = 100/214 (46%), Gaps = 16/214 (7%)
Query: 46 EEYQLLLQVTYRDSKEKRDLRNFLKLLKPPLLWSHG-----LIRIIRAKATTDCNSLNGV 100
EEY + +++++ ++ ++ +L L P+ HG + I+ TT C
Sbjct: 61 EEYTVNIEISFENASFLDPIKAYLNSLSFPI---HGNNTDQITDILSINVTTVCRPAGNE 117
Query: 101 LQCTCEDSYTWFPPSCLDPQNCYLHTAGALPSCECH-LNNLSQSVNFC---ERTKIWGTF 156
+ C+CE Y W CL C LP C L L + FC E +
Sbjct: 118 IWCSCETGYGWPRERCLHNLICQERDV-FLPGHHCSCLKELPPNGPFCLLQEDVTLNMRV 176
Query: 157 KINERFTNDLLNSSSAIYSKYANGIEIQLKKAYERIQGFESVQVTQFRNGSIVAGYEVVG 216
++N F DL+N+SSA+Y Y +E +K Y + GF+ V VT F++GS+V YEV
Sbjct: 177 RLNVGFQEDLMNTSSALYRSYKTDLETAFRKGYGILPGFKGVTVTGFKSGSVVVTYEVKT 236
Query: 217 SSSASELLSAIEHVAEKAKTALHKLFPLEDGSFR 250
+ + EL I E+ +L++ + ++ SF+
Sbjct: 237 TPPSLEL---IHKANEQVVQSLNQTYKMDYNSFQ 267
>gi|148719673 G-protein coupled receptor 116 [Homo sapiens]
Length = 1346
Score = 405 bits (1041), Expect = e-113
Identities = 240/665 (36%), Positives = 373/665 (56%), Gaps = 38/665 (5%)
Query: 257 CNDIVFGFGSKDDEYTLPC---------SSGYRGNITAKCESSGWQVIRETCVLSLLEEL 307
C D V G G C S G IT KC S W+ R C+ + + L
Sbjct: 669 CQDPVIGVGEPGKVIQKLCRFSNVPSSPESPIGGTITYKCVGSQWEEKRNDCISAPINSL 728
Query: 308 NKNFSMIVGNATE-AAVSSFVQNLSVII---RQNPSTTVGNLASVVSILSNISSLSLASH 363
+ ++ + ++ + +++++LS+ I S++ G+L ++++IL +S++
Sbjct: 729 LQMAKALIKSPSQDEMLPTYLKDLSISIDKAEHEISSSPGSLGAIINILDLLSTVPT--- 785
Query: 364 FRVSNSTMEDVISIADNILNSASVTNWTVLLREEKYASSRLLETLENIS-TLVPPTALPL 422
+V++ M V+S + IL + W VL ++ SS+LL ++E S L + PL
Sbjct: 786 -QVNSEMMTHVLSTVNVILGKPVLNTWKVLQQQWTNQSSQLLHSVERFSQALQSGDSPPL 844
Query: 423 NFSRKFIDWKGIPVNKSQLKRGYSYQIKMCPQNTSIPIRGRVLIGSDQFQRSLPET-IIS 481
+FS+ + + + S + +YQ + + G V+I + ++ I++
Sbjct: 845 SFSQTNVQMSSMVIKSSHPE---TYQQRFV--FPYFDLWGNVVIDKSYLENLQSDSSIVT 899
Query: 482 MASLTLGNILPVSKNGNAQVNGPVISTVIQNYSIN--EVFLFFSKIESNLSQPHCVFWDF 539
MA TL IL N V++T + + + + + F + + CVFW+F
Sbjct: 900 MAFPTLQAILAQDIQENNFAESLVMTTTVSHNTTMPFRISMTFKNNSPSGGETKCVFWNF 959
Query: 540 SHLQ----WNDAGCHLVNETQDIVTCQCTHLTSFSILMSPFVP---STIFPVVKWITYVG 592
W+ +GC++ D VTC C HLTSFSILMSP P S + ++ I+YVG
Sbjct: 960 RLANNTGGWDSSGCYVEEGDGDNVTCICDHLTSFSILMSPDSPDPSSLLGILLDIISYVG 1019
Query: 593 LGISIGSLILCLIIEALFWKQIKKSQTSHTRRICMVNIALSLLIADVWFIVGATVDTT-- 650
+G SI SL CL++EA+ WK + K++TS+ R C+VNIA SLL+A+ WFIV A +
Sbjct: 1020 VGFSILSLAACLVVEAVVWKSVTKNRTSYMRHTCIVNIAASLLVANTWFIVVAAIQDNRY 1079
Query: 651 VNPSGVCTAAVFFTHFFYLSLFFWMLMLGILLAYRIILVFHHMAQHLMMAVGFCLGYGCP 710
+ C AA FF HFFYLS+FFWML LG++L YR++ + H ++ A+ FCLGYGCP
Sbjct: 1080 ILCKTACVAATFFIHFFYLSVFFWMLTLGLMLFYRLVFILHETSRSTQKAIAFCLGYGCP 1139
Query: 711 LIISVITIAVTQPSNTYKRKDVCWLNWSNGSKPLLAFVVPALAIVAVNFVVVLLVLTKLW 770
L ISVIT+ TQP Y RK+VCWLNW + +K LLAF +PAL IV VN + ++V+TK+
Sbjct: 1140 LAISVITLGATQPREVYTRKNVCWLNWED-TKALLAFAIPALIIVVVNITITIVVITKIL 1198
Query: 771 RPTVGERLSRDDKATIIRVGKSLLILTPLLGLTWGFGIGTIVDSQNLAWHVIFALLNAFQ 830
RP++G++ + +K+++ ++ KS+ +LTPLLGLTWGFG+ T+ NL +H+IFA+LN FQ
Sbjct: 1199 RPSIGDKPCKQEKSSLFQISKSIGVLTPLLGLTWGFGLTTVFPGTNLVFHIIFAILNVFQ 1258
Query: 831 GFFILCFGILLDSKLRQLLFNKLSALSSWKQTEKQNSSDLSAKPKFSKPFNPLQNKGHYA 890
G FIL FG L D K+++ L NK S LS W +++S S+ P FS +P+ + +
Sbjct: 1259 GLFILLFGCLWDLKVQEALLNKFS-LSRWSSQHSKSTSLGSSTPVFSMS-SPISRRFNNL 1316
Query: 891 FSHTG 895
F TG
Sbjct: 1317 FGKTG 1321
Score = 84.7 bits (208), Expect = 3e-16
Identities = 60/214 (28%), Positives = 100/214 (46%), Gaps = 16/214 (7%)
Query: 46 EEYQLLLQVTYRDSKEKRDLRNFLKLLKPPLLWSHG-----LIRIIRAKATTDCNSLNGV 100
EEY + +++++ ++ ++ +L L P+ HG + I+ TT C
Sbjct: 61 EEYTVNIEISFENASFLDPIKAYLNSLSFPI---HGNNTDQITDILSINVTTVCRPAGNE 117
Query: 101 LQCTCEDSYTWFPPSCLDPQNCYLHTAGALPSCECH-LNNLSQSVNFC---ERTKIWGTF 156
+ C+CE Y W CL C LP C L L + FC E +
Sbjct: 118 IWCSCETGYGWPRERCLHNLICQERDV-FLPGHHCSCLKELPPNGPFCLLQEDVTLNMRV 176
Query: 157 KINERFTNDLLNSSSAIYSKYANGIEIQLKKAYERIQGFESVQVTQFRNGSIVAGYEVVG 216
++N F DL+N+SSA+Y Y +E +K Y + GF+ V VT F++GS+V YEV
Sbjct: 177 RLNVGFQEDLMNTSSALYRSYKTDLETAFRKGYGILPGFKGVTVTGFKSGSVVVTYEVKT 236
Query: 217 SSSASELLSAIEHVAEKAKTALHKLFPLEDGSFR 250
+ + EL I E+ +L++ + ++ SF+
Sbjct: 237 TPPSLEL---IHKANEQVVQSLNQTYKMDYNSFQ 267
>gi|116517328 G-protein coupled receptor 115 [Homo sapiens]
Length = 695
Score = 399 bits (1024), Expect = e-111
Identities = 241/631 (38%), Positives = 365/631 (57%), Gaps = 50/631 (7%)
Query: 274 PCSSGYRGNITAKCESSGWQVIRETCVLSLLEELNKNFSMIVGNATEAAVS--------- 324
PC+ + G I C WQ ETC +E+L K+ S + AA S
Sbjct: 65 PCAKDFHGEIGFTCNQKKWQKSAETCTSLSVEKLFKD-STGASRLSVAAPSIPLHILDFR 123
Query: 325 --SFVQNLSVIIRQN--------------PSTTVGNLASVVSILSNISSLSLASHFRVSN 368
+++++ IR+N TT GN+A +V +L NIS+ L+ + V+
Sbjct: 124 APETIESVAQGIRKNCPFDYACITDMVKSSETTSGNIAFIVELLKNIST-DLSDN--VTR 180
Query: 369 STMEDVISIADNILNSASVTNWTVLLREEKYASSRLLETLENISTLVPPTALPLNFSRK- 427
M+ +A++IL++A+++NW + K ASS LL+++ + + N +
Sbjct: 181 EKMKSYSEVANHILDTAAISNWAFI--PNKNASSDLLQSVNLFARQLHIHNNSENIVNEL 238
Query: 428 FIDWKGIPVNKSQLKRGYSYQIKMCPQNTSIPIRGRVLIGSDQFQRSLPET--IISMASL 485
FI KG +N + ++ ++ + M NT+ I G V I + ++ P IS+A
Sbjct: 239 FIQTKGFHINHNTSEKSLNFSMSM--NNTTEDILGMVQIPRQELRKLWPNASQAISIAFP 296
Query: 486 TLGNILPVSKNGNA----QVNGPVISTVIQNYSINEVFLFFSKI-ESNLSQPHCVFWDFS 540
TLG IL + N QVNG V+S V+ + E+ L F KI ++ ++ CV W
Sbjct: 297 TLGAILREAHLQNVSLPRQVNGLVLSVVLPE-RLQEIILTFEKINKTRNARAQCVGWHSK 355
Query: 541 HLQWNDAGCHLVNETQDIVTCQCTHLT---SFSILMSPFVPSTIFPVVKWITYVGLGISI 597
+W++ C ++ + ++ V C+C + + SFSILMS S V+ +IT +GL +SI
Sbjct: 356 KRRWDEKACQMMLDIRNEVKCRCNYTSVVMSFSILMSS--KSMTDKVLDYITCIGLSVSI 413
Query: 598 GSLILCLIIEALFWKQIKKSQTSHTRRICMVNIALSLLIADVWFIVGATVDTTVNPSGVC 657
SL+LCLIIEA W ++ ++ S+ R +C+VNIA+SLL A+VWFI+G+ + +C
Sbjct: 414 LSLVLCLIIEATVWSRVVVTEISYMRHVCIVNIAVSLLTANVWFIIGSHFNIKAQDYNMC 473
Query: 658 TAAVFFTHFFYLSLFFWMLMLGILLAYRIILVFHHMAQHLMMAVGFCLGYGCPLIISVIT 717
A FF+HFFYLSLFFWML +L+ Y I+++F M + MM +GF +GYGCPLII+V T
Sbjct: 474 VAVTFFSHFFYLSLFFWMLFKALLIIYGILVIFRRMMKSRMMVIGFAIGYGCPLIIAVTT 533
Query: 718 IAVTQPSNTYKRKDVCWLNWSNGSKPLLAFVVPALAIVAVNFVVVLLVLTKLWRPTVGER 777
+A+T+P Y R + CWLNW N +K LLAF +PA IVAVN +VVL+V RP++G
Sbjct: 534 VAITEPEKGYMRPEACWLNWDN-TKALLAFAIPAFVIVAVNLIVVLVVAVNTQRPSIGSS 592
Query: 778 LSRDDKATIIRVGKSLLILTPLLGLTWGFGIGTIVDSQNLAWHVIFALLNAFQGFFILCF 837
S+ D I+R+ K++ ILTPLLGLTWGFGI T+++ +L +H+IFALLNAFQGFFIL F
Sbjct: 593 KSQ-DVVIIMRISKNVAILTPLLGLTWGFGIATLIEGTSLTFHIIFALLNAFQGFFILLF 651
Query: 838 GILLDSKLRQLLFNKLSALSSWKQTEKQNSS 868
G ++D K+R L ++S+L K +N+S
Sbjct: 652 GTIMDHKIRDALRMRMSSLKG-KSRAAENAS 681
>gi|223556012 G-protein coupled receptor 113 isoform 1 [Homo sapiens]
Length = 1079
Score = 268 bits (686), Expect = 1e-71
Identities = 185/605 (30%), Positives = 312/605 (51%), Gaps = 54/605 (8%)
Query: 274 PCSSGYRGNITAKCESSG-WQVIRETCVLSLLEELNKNFSMIVGNATEAAVSSFVQNLSV 332
PC RG + C + G W + +C + L L ++ +A S + +
Sbjct: 452 PCPESKRGIVRRLCGADGVWGPVHSSCTDARLLALFTRTKLL-----QAGQGSPAEEVPQ 506
Query: 333 IIRQNP-----STTVGNLASVVSILSNISSLSLASHFRVSNSTMEDVISIADNILNSASV 387
I+ Q P +++ +L +++S + ++ + + ++ +++++ D +L+ +
Sbjct: 507 ILAQLPGQAAEASSPSDLLTLLSTMKYVAKVVAEARIQLDRRALKNLLIATDKVLDMDTR 566
Query: 388 TNWTVLLREEKYASSRLLETLENISTLVPPTALPLNFSRKFIDWKGIPVNKSQLKRGYSY 447
+ WT+ + +A S LL +E ++ + P P FS + + +SQL G ++
Sbjct: 567 SLWTLAQARKPWAGSTLLLAVETLACSLCPQDHPFAFSLPNV------LLQSQLF-GPTF 619
Query: 448 QIKMCPQNTSIPIRGRVLIGSDQFQRSLPETI-----ISMASLTL---GNILPVSKN--- 496
P + SI R + + + SL + IS+ SL L ++LP +
Sbjct: 620 -----PADYSISFPTRPPLQAQIPRHSLAPLVRNGTEISITSLVLRKLDHLLPSNYGQGL 674
Query: 497 GNAQVNGPVISTVI------QNYSINEVFLFFSKIESNLSQPHCVFWDFSHLQ----WND 546
G++ P + VI + +S EV + F + + PHCVFWD S Q W+
Sbjct: 675 GDSLYATPGLVLVISIMAGDRAFSQGEVIMDFGNTDGS---PHCVFWDHSLFQGRGGWSK 731
Query: 547 AGCHL-VNETQDIVTCQCTHLTSFSILMSPF-VPSTIFPVVKWITYVGLGISIGSLILCL 604
GC V C C HLT+FS+LMSP VP P + +T VGLG SI +L++CL
Sbjct: 732 EGCQAQVASASPTAQCLCQHLTAFSVLMSPHTVPEE--PALALLTQVGLGASILALLVCL 789
Query: 605 IIEALFWKQIKKSQTSHTRRICMVNIALSLLIADVWFIVGATVDTTVNPSGVCTAAVFFT 664
+ L W+ + +++ S+ R ++N+ LL AD F+ GA + S +C AA F
Sbjct: 790 GVYWLVWRVVVRNKISYFRHAALLNMVFCLLAADTCFL-GAPFLSPGPRSPLCLAAAFLC 848
Query: 665 HFFYLSLFFWMLMLGILLAYRIILVFHHMAQHLMMAVGFCLGYGCPLIISVITIAVTQPS 724
HF YL+ FFWML ++LA++++ VFH +A+H ++ + LGY CPL ++ +T+ + P
Sbjct: 849 HFLYLATFFWMLAQALVLAHQLLFVFHQLAKHRVLPLMVLLGYLCPLGLAGVTLGLYLPQ 908
Query: 725 NTYKRKDVCWLNWSNGSKPLLAFVVPALAIVAVNFVVVLLVLTKLWRPTVGERLSRDDKA 784
Y R+ CWL+ G+ L FV P LAI+ VN +V+ + + KL RP++ E + +
Sbjct: 909 GQYLREGECWLDGKGGA--LYTFVGPVLAIIGVNGLVLAMAMLKLLRPSLSEGPPAEKRQ 966
Query: 785 TIIRVGKSLLILTPLLGLTWGFGIGTIVDSQNLAWHVIFALLNAFQGFFILCFGILLDSK 844
++ V K+LLILTP+ GLTWG G+ T+++ + H IF +LN QG FIL FG L+D K
Sbjct: 967 ALLGVIKALLILTPIFGLTWGLGLATLLEEVSTVPHYIFTILNTLQGVFILLFGCLMDRK 1026
Query: 845 LRQLL 849
+++ L
Sbjct: 1027 IQEAL 1031
>gi|223556014 G-protein coupled receptor 113 isoform 2 [Homo
sapiens]
Length = 997
Score = 268 bits (686), Expect = 1e-71
Identities = 185/605 (30%), Positives = 312/605 (51%), Gaps = 54/605 (8%)
Query: 274 PCSSGYRGNITAKCESSG-WQVIRETCVLSLLEELNKNFSMIVGNATEAAVSSFVQNLSV 332
PC RG + C + G W + +C + L L ++ +A S + +
Sbjct: 383 PCPESKRGIVRRLCGADGVWGPVHSSCTDARLLALFTRTKLL-----QAGQGSPAEEVPQ 437
Query: 333 IIRQNP-----STTVGNLASVVSILSNISSLSLASHFRVSNSTMEDVISIADNILNSASV 387
I+ Q P +++ +L +++S + ++ + + ++ +++++ D +L+ +
Sbjct: 438 ILAQLPGQAAEASSPSDLLTLLSTMKYVAKVVAEARIQLDRRALKNLLIATDKVLDMDTR 497
Query: 388 TNWTVLLREEKYASSRLLETLENISTLVPPTALPLNFSRKFIDWKGIPVNKSQLKRGYSY 447
+ WT+ + +A S LL +E ++ + P P FS + + +SQL G ++
Sbjct: 498 SLWTLAQARKPWAGSTLLLAVETLACSLCPQDHPFAFSLPNV------LLQSQLF-GPTF 550
Query: 448 QIKMCPQNTSIPIRGRVLIGSDQFQRSLPETI-----ISMASLTL---GNILPVSKN--- 496
P + SI R + + + SL + IS+ SL L ++LP +
Sbjct: 551 -----PADYSISFPTRPPLQAQIPRHSLAPLVRNGTEISITSLVLRKLDHLLPSNYGQGL 605
Query: 497 GNAQVNGPVISTVI------QNYSINEVFLFFSKIESNLSQPHCVFWDFSHLQ----WND 546
G++ P + VI + +S EV + F + + PHCVFWD S Q W+
Sbjct: 606 GDSLYATPGLVLVISIMAGDRAFSQGEVIMDFGNTDGS---PHCVFWDHSLFQGRGGWSK 662
Query: 547 AGCHL-VNETQDIVTCQCTHLTSFSILMSPF-VPSTIFPVVKWITYVGLGISIGSLILCL 604
GC V C C HLT+FS+LMSP VP P + +T VGLG SI +L++CL
Sbjct: 663 EGCQAQVASASPTAQCLCQHLTAFSVLMSPHTVPEE--PALALLTQVGLGASILALLVCL 720
Query: 605 IIEALFWKQIKKSQTSHTRRICMVNIALSLLIADVWFIVGATVDTTVNPSGVCTAAVFFT 664
+ L W+ + +++ S+ R ++N+ LL AD F+ GA + S +C AA F
Sbjct: 721 GVYWLVWRVVVRNKISYFRHAALLNMVFCLLAADTCFL-GAPFLSPGPRSPLCLAAAFLC 779
Query: 665 HFFYLSLFFWMLMLGILLAYRIILVFHHMAQHLMMAVGFCLGYGCPLIISVITIAVTQPS 724
HF YL+ FFWML ++LA++++ VFH +A+H ++ + LGY CPL ++ +T+ + P
Sbjct: 780 HFLYLATFFWMLAQALVLAHQLLFVFHQLAKHRVLPLMVLLGYLCPLGLAGVTLGLYLPQ 839
Query: 725 NTYKRKDVCWLNWSNGSKPLLAFVVPALAIVAVNFVVVLLVLTKLWRPTVGERLSRDDKA 784
Y R+ CWL+ G+ L FV P LAI+ VN +V+ + + KL RP++ E + +
Sbjct: 840 GQYLREGECWLDGKGGA--LYTFVGPVLAIIGVNGLVLAMAMLKLLRPSLSEGPPAEKRQ 897
Query: 785 TIIRVGKSLLILTPLLGLTWGFGIGTIVDSQNLAWHVIFALLNAFQGFFILCFGILLDSK 844
++ V K+LLILTP+ GLTWG G+ T+++ + H IF +LN QG FIL FG L+D K
Sbjct: 898 ALLGVIKALLILTPIFGLTWGLGLATLLEEVSTVPHYIFTILNTLQGVFILLFGCLMDRK 957
Query: 845 LRQLL 849
+++ L
Sbjct: 958 IQEAL 962
>gi|141802362 G-protein coupled receptor 113 isoform 3 [Homo
sapiens]
Length = 873
Score = 268 bits (686), Expect = 1e-71
Identities = 185/605 (30%), Positives = 312/605 (51%), Gaps = 54/605 (8%)
Query: 274 PCSSGYRGNITAKCESSG-WQVIRETCVLSLLEELNKNFSMIVGNATEAAVSSFVQNLSV 332
PC RG + C + G W + +C + L L ++ +A S + +
Sbjct: 253 PCPESKRGIVRRLCGADGVWGPVHSSCTDARLLALFTRTKLL-----QAGQGSPAEEVPQ 307
Query: 333 IIRQNP-----STTVGNLASVVSILSNISSLSLASHFRVSNSTMEDVISIADNILNSASV 387
I+ Q P +++ +L +++S + ++ + + ++ +++++ D +L+ +
Sbjct: 308 ILAQLPGQAAEASSPSDLLTLLSTMKYVAKVVAEARIQLDRRALKNLLIATDKVLDMDTR 367
Query: 388 TNWTVLLREEKYASSRLLETLENISTLVPPTALPLNFSRKFIDWKGIPVNKSQLKRGYSY 447
+ WT+ + +A S LL +E ++ + P P FS + + +SQL G ++
Sbjct: 368 SLWTLAQARKPWAGSTLLLAVETLACSLCPQDHPFAFSLPNV------LLQSQLF-GPTF 420
Query: 448 QIKMCPQNTSIPIRGRVLIGSDQFQRSLPETI-----ISMASLTL---GNILPVSKN--- 496
P + SI R + + + SL + IS+ SL L ++LP +
Sbjct: 421 -----PADYSISFPTRPPLQAQIPRHSLAPLVRNGTEISITSLVLRKLDHLLPSNYGQGL 475
Query: 497 GNAQVNGPVISTVI------QNYSINEVFLFFSKIESNLSQPHCVFWDFSHLQ----WND 546
G++ P + VI + +S EV + F + + PHCVFWD S Q W+
Sbjct: 476 GDSLYATPGLVLVISIMAGDRAFSQGEVIMDFGNTDGS---PHCVFWDHSLFQGRGGWSK 532
Query: 547 AGCHL-VNETQDIVTCQCTHLTSFSILMSPF-VPSTIFPVVKWITYVGLGISIGSLILCL 604
GC V C C HLT+FS+LMSP VP P + +T VGLG SI +L++CL
Sbjct: 533 EGCQAQVASASPTAQCLCQHLTAFSVLMSPHTVPEE--PALALLTQVGLGASILALLVCL 590
Query: 605 IIEALFWKQIKKSQTSHTRRICMVNIALSLLIADVWFIVGATVDTTVNPSGVCTAAVFFT 664
+ L W+ + +++ S+ R ++N+ LL AD F+ GA + S +C AA F
Sbjct: 591 GVYWLVWRVVVRNKISYFRHAALLNMVFCLLAADTCFL-GAPFLSPGPRSPLCLAAAFLC 649
Query: 665 HFFYLSLFFWMLMLGILLAYRIILVFHHMAQHLMMAVGFCLGYGCPLIISVITIAVTQPS 724
HF YL+ FFWML ++LA++++ VFH +A+H ++ + LGY CPL ++ +T+ + P
Sbjct: 650 HFLYLATFFWMLAQALVLAHQLLFVFHQLAKHRVLPLMVLLGYLCPLGLAGVTLGLYLPQ 709
Query: 725 NTYKRKDVCWLNWSNGSKPLLAFVVPALAIVAVNFVVVLLVLTKLWRPTVGERLSRDDKA 784
Y R+ CWL+ G+ L FV P LAI+ VN +V+ + + KL RP++ E + +
Sbjct: 710 GQYLREGECWLDGKGGA--LYTFVGPVLAIIGVNGLVLAMAMLKLLRPSLSEGPPAEKRQ 767
Query: 785 TIIRVGKSLLILTPLLGLTWGFGIGTIVDSQNLAWHVIFALLNAFQGFFILCFGILLDSK 844
++ V K+LLILTP+ GLTWG G+ T+++ + H IF +LN QG FIL FG L+D K
Sbjct: 768 ALLGVIKALLILTPIFGLTWGLGLATLLEEVSTVPHYIFTILNTLQGVFILLFGCLMDRK 827
Query: 845 LRQLL 849
+++ L
Sbjct: 828 IQEAL 832
>gi|163792198 latrophilin 3 precursor [Homo sapiens]
Length = 1469
Score = 154 bits (390), Expect = 3e-37
Identities = 153/621 (24%), Positives = 275/621 (44%), Gaps = 86/621 (13%)
Query: 275 CSSGYRGNITAKCES--SGWQVIRETCVLSLLEELNKNFSMIVGNATEAAVSSFVQNLSV 332
CSS + +IT K +S + + RE L E +N + G+ T + V + Q + +
Sbjct: 550 CSSPWVNHITQKLKSGETAANIARE------LAEQTRNH-LNAGDITYS-VRAMDQLVGL 601
Query: 333 IIRQNPSTTVGNLASVVSILSNISSLSLASHFRVSNSTMEDVISIADNILNSASVTNWTV 392
+ Q + T G S L+ + R + ++ ++ +N+L ++ W
Sbjct: 602 LDVQLRNLTPGGKDSAARSLNKLQKRE-----RSCRAYVQAMVETVNNLLQPQALNAWRD 656
Query: 393 LLREEKY-ASSRLLETLENISTLVPPTALPLNFSRKFIDWKGIPVNKSQLKRGYSYQIKM 451
L ++ A++ LL T+E + ++ L + R+ D I + ++L + +
Sbjct: 657 LTTSDQLRAATMLLHTVEESAFVLADNLLKTDIVRENTD--NIKLEVARLSTEGNLEDLK 714
Query: 452 CPQN----TSIPI----------RGRVLIGSDQFQRSLPETIISMASLTLGNILPVSKNG 497
P+N ++I + G + + + P AS+ LG +S N
Sbjct: 715 FPENMGHGSTIQLSANTLKQNGRNGEIRVAFVLYNNLGPYLSTENASMKLGTEA-LSTNH 773
Query: 498 NAQVNGPVISTVIQNYSINEVFL---------FFSKIESNLSQPHCVFWDFSHLQ----W 544
+ VN PVI+ I N+V+L + E N + P+C FW +S W
Sbjct: 774 SVIVNSPVITAAINKEFSNKVYLADPVVFTVKHIKQSEENFN-PNCSFWSYSKRTMTGYW 832
Query: 545 NDAGCHLVNETQDIVTCQCTHLTSFSILM-------SPFVPSTIFPVVKWITYVGLGISI 597
+ GC L+ + TC C HLT+F++LM S V + V+ W VG+ +S+
Sbjct: 833 STQGCRLLTTNKTHTTCSCNHLTNFAVLMAHVEVKHSDAVHDLLLDVITW---VGILLSL 889
Query: 598 GSLILCLIIEALFWKQIKKSQTSHTRRICMVNIALSLLIADVWFIVGATVDTTVNPSGVC 657
L++C+ F T H N+ +SL +A++ F++G ++ T P C
Sbjct: 890 VCLLICIFTFCFFRGLQSDRNTIHK------NLCISLFVAELLFLIG--INRTDQPI-AC 940
Query: 658 TAAVFFTHFFYLSLFFWMLMLGILLAYRIILVFHHMAQHLMMAVGFCLGYGCPLIISVIT 717
HFF+L+ F WM + G+ L ++ VF ++H + +GYG P +I ++
Sbjct: 941 AVFAALLHFFFLAAFTWMFLEGVQLYIMLVEVFE--SEHSRRKYFYLVGYGMPALIVAVS 998
Query: 718 IAVTQPSNTYKRKDVCWLNWSNGSKPLLAFVVPALAIVAVNFVVVLLVLTKLW------R 771
AV S Y VCWL + + +F+ PA I+ +N + + + L K++ +
Sbjct: 999 AAVDYRS--YGTDKVCWLRLD--TYFIWSFIGPATLIIMLNVIFLGIALYKMFHHTAILK 1054
Query: 772 PTVG--ERLSRDDKATIIR---VGKSLLILTPLLGLTWGFGIGTIVDSQNLAWHVIFALL 826
P G + ++ +D I+ +G L+ LLGLTW FG+ ++ + +F +
Sbjct: 1055 PESGCLDNINYEDNRPFIKSWVIGAIALLC--LLGLTWAFGL-MYINESTVIMAYLFTIF 1111
Query: 827 NAFQGFFILCFGILLDSKLRQ 847
N+ QG FI F +L K+R+
Sbjct: 1112 NSLQGMFIFIFHCVLQKKVRK 1132
>gi|45433552 G protein-coupled receptor 133 [Homo sapiens]
Length = 874
Score = 145 bits (367), Expect = 1e-34
Identities = 105/362 (29%), Positives = 177/362 (48%), Gaps = 31/362 (8%)
Query: 527 SNLSQPHCVFWDFSHLQ--WNDAGCHLVNETQDIVTCQCTHLTSFSILMSPFVPSTIFP- 583
SN +C F DFS + W++ GC L C+CTHLT+F+ILM VP +
Sbjct: 503 SNRVFVYCAFLDFSSGEGVWSNHGCALTRGNLTYSVCRCTHLTNFAILMQ-VVPLELARG 561
Query: 584 ---VVKWITYVGLGISIGSLILCLIIEALFWKQIKKSQTSHTRRICM-VNIALSLLIADV 639
+ I+YVG +S+ LCL+ + + + T +R + N++ ++L+A V
Sbjct: 562 HQVALSSISYVGCSLSV----LCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQV 617
Query: 640 WFIVGATVDTTVNPSGVCTAAVFFTHFFYLSLFFWMLMLGILLAYRIILVFHHMAQHLMM 699
++ ++ P C H+F+LS F WML+ G+ L +I VF
Sbjct: 618 LLLISFRLEPGTTP---CQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHRY 674
Query: 700 AVGFCLGYGCPLIISVITIAVTQPSNTYKRKDVCWLNWSNGSKPLLAFVVPALAIVAVNF 759
G +G+G PL+I +I+++ S Y + CWL+ ++G+ + AFV PAL ++ VN
Sbjct: 675 YYG--MGWGFPLLICIISLSFAMDS--YGTSNNCWLSLASGA--IWAFVAPALFVIVVNI 728
Query: 760 VVVLLVLTKLWRPTVGERLSRDDKATIIRVGKSLLILTPLLGLTWGFGIGTIVDSQNLAW 819
+++ V + + + D + K++ +L P+LG +W FG+ V+ + +
Sbjct: 729 GILIAVTRVISQISADNYKIHGDPSAFKLTAKAVAVLLPILGTSWVFGV-LAVNGCAVVF 787
Query: 820 HVIFALLNAFQGFFILCFGILLDSKLRQLLFNKLSALSSWKQTEKQNSSDLSAKPKFSKP 879
+FA LN+ QG FI F LL+S++R +K W T SA+ +KP
Sbjct: 788 QYMFATLNSLQGLFIFLFHCLLNSEVRAAFKHKTKV---WSLTSS------SARTSNAKP 838
Query: 880 FN 881
F+
Sbjct: 839 FH 840
>gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [Homo
sapiens]
Length = 1584
Score = 139 bits (350), Expect = 1e-32
Identities = 135/566 (23%), Positives = 237/566 (41%), Gaps = 87/566 (15%)
Query: 323 VSSFVQNLSVIIRQNPSTTVGNLASVVSILSNISSLSLASHFRVSNSTMEDVISIADNIL 382
VS +Q L V I Q+ ++ G+L S + +L N++ + +++ + +++ + I N+L
Sbjct: 662 VSEVIQTL-VEISQDGTSYSGDLLSTIDVLRNMTEIFRRAYYSPTPGDVQNFVQILSNLL 720
Query: 383 NSASVTNWTVLLREEKYASSRLLETLENISTLVPPTALPLNFSRKFIDWKGIPVNKSQLK 442
+ W E + A E + V + R + Q+
Sbjct: 721 AEENRDKW----EEAQLAGPNAKELFRLVEDFVDVIGFRMKDLR----------DAYQVT 766
Query: 443 RGYSYQIKMCPQN----TSIPIRG-------------RVLIGSDQFQRSLPET------- 478
I P + S P++G RV + F L E
Sbjct: 767 DNLVLSIHKLPASGATDISFPMKGWRATGDWAKVPEDRVTVSKSVFSTGLTEADEASVFV 826
Query: 479 IISMASLTLGNILPVSKNGNAQVNGPVISTVIQ---NYSINEVFLFFSKIESNLSQPHCV 535
+ ++ LG+ L + +N +N VIS ++ + + F+ + + + C+
Sbjct: 827 VGTVLYRNLGSFLALQRNTTV-LNSKVISVTVKPPPRSLRTPLEIEFAHMYNGTTNQTCI 885
Query: 536 FWDFSHLQ----------WNDAGCHLVNETQDIVTCQCTHLTSFSILMSPFVPSTI---- 581
WD + + W+ GC V C C L++F+IL + +
Sbjct: 886 LWDETDVPSSSAPPQLGPWSWRGCRTVPLDALRTRCLCDRLSTFAILAQLSADANMEKAT 945
Query: 582 FPVVKWITYVGLGISIGSLILCLIIEALFWKQIKKSQTSHTRRICMVNIALSLLIADVWF 641
P V I VG G+S +L++ +II W+ I+ R + ++N LS++ ++
Sbjct: 946 LPSVTLI--VGCGVSSLTLLMLVIIYVSVWRYIRSE-----RSVILINFCLSIISSNALI 998
Query: 642 IVGATVDTTVNPSGVCTAAVFFTHFFYLSLFFWMLMLGILLAYRIILVFHHMAQHLMMAV 701
++G T VCT F HFF+LS F W+L + V H+ L+
Sbjct: 999 LIG---QTQTRNKVVCTLVAAFLHFFFLSSFCWVLTEAW---QSYMAVTGHLRNRLIRKR 1052
Query: 702 GFCLGYGCPLIISVITIAVTQPSNTYKRKDVCWLNWSNGSKPLLAFVVPALAIVAVNFVV 761
CLG+G P ++ I++ T+ Y + CWL+ G L AFV PA A+V VN V+
Sbjct: 1053 FLCLGWGLPALVVAISVGFTKAKG-YSTMNYCWLSLEGGL--LYAFVGPAAAVVLVNMVI 1109
Query: 762 VLLVLTKLWRPTVGERLSRD---DKATIIRVGKSL---LILTPLLGLTWGFGIGTIVDSQ 815
+LV KL +S+D DK R G SL ++ PLL LTW + + D +
Sbjct: 1110 GILVFNKL--------VSKDGITDKKLKERAGASLWSSCVVLPLLALTWMSAVLAVTDRR 1161
Query: 816 NLAWHVIFALLNAFQGFFILCFGILL 841
+ + ++FA+ ++ +GF I+ +L
Sbjct: 1162 SALFQILFAVFDSLEGFVIVMVHCIL 1187
>gi|133930786 egf-like module-containing mucin-like receptor 3 [Homo
sapiens]
Length = 652
Score = 139 bits (350), Expect = 1e-32
Identities = 123/443 (27%), Positives = 218/443 (49%), Gaps = 53/443 (11%)
Query: 429 IDWKGIPVNKSQLKRGYSYQIKMCPQNTSIPIRGRVLIGSDQFQRSLPETIISMASLTLG 488
I+ + I N S+ ++ ++ ++M S+ IR +I D P I ++ +LG
Sbjct: 194 IETQAITDNCSEERKTFNLNVQM----NSMDIRCSDIIQGDT---QGPSAIAFISYSSLG 246
Query: 489 NIL------PVSKNGNAQVNGPVISTVI---QNYSINE-VFLFFS--KIESNLSQPHCVF 536
NI+ + K +N V+S I +N S+++ V L F K+ + + CV+
Sbjct: 247 NIINATFFEEMDKKDQVYLNSQVVSAAIGPKRNVSLSKSVTLTFQHVKMTPSTKKVFCVY 306
Query: 537 WDFSHL--QWNDAGCHLVNETQDIVTCQCTHLTSFSILMSPFVPSTIFPVVKWITYVGLG 594
W + QW+ GC L++ + C C+HL+SF++LM+ PV+ ITYVGL
Sbjct: 307 WKSTGQGSQWSRDGCFLIHVNKSHTMCNCSHLSSFAVLMA-LTSQEEDPVLTVITYVGLS 365
Query: 595 ISIGSLILCLIIEALFW---KQIKKSQTSHTRRICMVNIALSLLIADVWFIVGATVDTTV 651
+S +LCL++ AL + K I+ + TS + ++L L +A + F+VG +D T
Sbjct: 366 VS----LLCLLLAALTFLLCKAIRNTSTS-----LHLQLSLCLFLAHLLFLVG--IDRT- 413
Query: 652 NPSGVCTAAVFFTHFFYLSLFFWMLMLGI---LLAYRIILVFHHMAQHLMMAVGFCLGYG 708
P +C+ H+ YL+ F WML+ G+ L A + +V + LM + F +GYG
Sbjct: 414 EPKVLCSIIAGALHYLYLAAFTWMLLEGVHLFLTARNLTVVNYSSINRLMKWIMFPVGYG 473
Query: 709 CPLIISVITIAVTQPS--NTYKRKDVCWLNWSNGSKPLLAFVVPALAIVAVNFVVVLLVL 766
P +T+A++ S + Y D CWL+ G + +F+ P AI + N V+ +LV
Sbjct: 474 VP----AVTVAISAASWPHLYGTADRCWLHLDQGF--MWSFLGPVCAIFSANLVLFILVF 527
Query: 767 TKLWR--PTVGERLSRDDKATIIRVGKSLLILTPLLGLTWGFGIGTIVDSQNLAWHVIFA 824
L R ++ +S ++ + + +LG TW G+ + + + + +F
Sbjct: 528 WILKRKLSSLNSEVSTIQNTRMLAFKATAQLF--ILGCTWCLGLLQVGPAAQVMAY-LFT 584
Query: 825 LLNAFQGFFILCFGILLDSKLRQ 847
++N+ QGFFI LL ++++
Sbjct: 585 IINSLQGFFIFLVYCLLSQQVQK 607
>gi|6912464 latrophilin 2 precursor [Homo sapiens]
Length = 1403
Score = 137 bits (344), Expect = 6e-32
Identities = 140/615 (22%), Positives = 260/615 (42%), Gaps = 66/615 (10%)
Query: 274 PCSSGYRGNITAKC--ESSGWQVIR---ETCVLSLLEELNKNFSMIVGNATEAAVSSFVQ 328
PC G RG + C + W C + +L + NA A
Sbjct: 491 PCPKGTRGTASYLCMISTGTWNPKGPDLSNCTSHWVNQLAQKIRS-GENAASLANELAKH 549
Query: 329 NLSVIIRQNPSTTVGNLASVVSIL-SNISSLSLASHFRVSNSTMEDVISIADNILNSASV 387
+ + S++V + +V IL + + L + S + ++ DN+L ++
Sbjct: 550 TKGPVFAGDVSSSVRLMEQLVDILDAQLQELKPSEKDSAGRSYNKAIVDTVDNLLRPEAL 609
Query: 388 TNWTVL-LREEKYASSRLLETLEN-----ISTLVPPTALPLNFSRKFIDWKGIPVNKSQL 441
+W + E+ + ++ LL+TLE L+ PT + + ++ + + Q+
Sbjct: 610 ESWKHMNSSEQAHTATMLLDTLEEGAFVLADNLLEPTRVSMPTENIVLE-VAVLSTEGQI 668
Query: 442 KRGYSYQIKMCPQNTSIPIRGRVLIGSDQFQRSLPETIISMASLTLGNILP--------- 492
+ + + + + +SI + + Q R+ ++ + +LG L
Sbjct: 669 Q-DFKFPLGIKGAGSSIQLSANTV---KQNSRNGLAKLVFIIYRSLGQFLSTENATIKLG 724
Query: 493 ---VSKNGNAQVNGPVISTVIQN-----YSINEVFLFFSKIE-SNLSQPHCVFWDFSHLQ 543
+ +N VN VIS I Y + V I+ N +C FW++S
Sbjct: 725 ADFIGRNSTIAVNSHVISVSINKESSRVYLTDPVLFTLPHIDPDNYFNANCSFWNYSERT 784
Query: 544 ----WNDAGCHLVNETQDIVTCQCTHLTSFSILMS----PFVPSTIFPVVKWITYVGLGI 595
W+ GC LV+ + TC C+HLT+F+ILM+ + ++ IT+VG+ I
Sbjct: 785 MMGYWSTQGCKLVDTNKTRTTCACSHLTNFAILMAHREIAYKDGVHELLLTVITWVGIVI 844
Query: 596 SIGSLILCLIIEALFWKQIKKSQTSHTRRICMVNIALSLLIADVWFIVGATVDTTVNPSG 655
S+ L +C+ F T H N+ ++L IA+ F++G +D T +
Sbjct: 845 SLVCLAICIFTFCFFRGLQSDRNTIHK------NLCINLFIAEFIFLIG--IDKT-KYAI 895
Query: 656 VCTAAVFFTHFFYLSLFFWMLMLGILLAYRIILVFHHMAQHLMMAVGFCLGYGCPLIISV 715
C HFF+L+ F WM + G+ L ++ VF +++ + GY P +
Sbjct: 896 ACPIFAGLLHFFFLAAFAWMCLEGVQLYLMLVEVFE--SEYSRKKYYYVAGYLFPATVVG 953
Query: 716 ITIAVTQPSNTYKRKDVCWLNWSNGSKPLLAFVVPALAIVAVNFVVVLLVLTKLWRPTVG 775
++ A+ S Y + CWL+ N + +F+ P I+ +N + +++ L K+ + +
Sbjct: 954 VSAAIDYKS--YGTEKACWLHVDNYF--IWSFIGPVTFIILLNIIFLVITLCKMVKHS-- 1007
Query: 776 ERLSRDDKATIIRVGKSLL---ILTPLLGLTWGFGIGTIVDSQNLAWHVIFALLNAFQGF 832
+ D + + + +L L LLGLTW FG+ ++ + + +F + NAFQG
Sbjct: 1008 -NTLKPDSSRLENIKSWVLGAFALLCLLGLTWSFGL-LFINEETIVMAYLFTIFNAFQGV 1065
Query: 833 FILCFGILLDSKLRQ 847
FI F L K+R+
Sbjct: 1066 FIFIFHCALQKKVRK 1080
>gi|148806925 EGF, latrophilin and seven transmembrane domain
containing 1 [Homo sapiens]
Length = 690
Score = 134 bits (338), Expect = 3e-31
Identities = 132/564 (23%), Positives = 251/564 (44%), Gaps = 47/564 (8%)
Query: 301 LSLLEELNKNFSMIVGNATEAAVSSFVQNLSVIIRQNPSTTVGNLASVVSILSNISSLSL 360
++LL+E+ +N + T+ + + + + ++ S+ +G + +S +S+ +L
Sbjct: 140 VALLQEVYRN------SVTDLSPTDIITYIEILAES--SSLLGYKNNTISAKDTLSNSTL 191
Query: 361 ASHFR-VSNSTMEDVISIADNILNSASVTNWTVLLREEKYASSRLLETLENISTLVPPTA 419
+ V+N D + D + + T+ T L+ + A+ R+ ++ + +T +
Sbjct: 192 TEFVKTVNNFVQRDTFVVWDKLSVNHRRTHLTKLMHTVEQATLRISQSFQK-TTEFDTNS 250
Query: 420 LPLNFSRKFIDWKGIPVNKSQLKRGYSYQIKMCPQNTSIPIRGRVLIGSDQFQRSLPETI 479
+ F D + + Y + + G V + ++ P
Sbjct: 251 TDIALKVFFFDSYNMKHIHPHMNMDGDYINIFPKRKAAYDSNGNVAVAFVYYKSIGP--- 307
Query: 480 ISMASLTLGNILPVSKNGNAQVNGPVISTVIQ-NYSINEVFLF-FSKIESNLSQPH---- 533
+ S + +L N++ VIS+VI + S N L+ KI LS
Sbjct: 308 --LLSSSDNFLLKPQNYDNSEEEERVISSVISVSMSSNPPTLYELEKITFTLSHRKVTDR 365
Query: 534 ----CVFWDFS----HLQWNDAGCHLVNETQDIVTCQCTHLTSFSILMS--PFVPSTIFP 583
C FW++S + W+ GC L + +C+C HLT F+ILMS P + +
Sbjct: 366 YRSLCAFWNYSPDTMNGSWSSEGCELTYSNETHTSCRCNHLTHFAILMSSGPSIGIKDYN 425
Query: 584 VVKWITYVGLGISIGSLILCLIIEALFWKQIKKSQTSHTRRICMVNIALSLLIADVWFIV 643
++ IT +G+ IS+ L +C I F+ +I+ ++T+ + +C SL +A++ F+V
Sbjct: 426 ILTRITQLGIIISLICLAIC-IFTFWFFSEIQSTRTTIHKNLC-----CSLFLAELVFLV 479
Query: 644 GATVDTTVNPSGVCTAAVFFTHFFYLSLFFWMLMLGILLAYRIILVFHHMAQHLMMAVGF 703
G +T C+ H+F+L+ F WM + GI L ++ V ++ + + +
Sbjct: 480 GINTNTN---KLFCSIIAGLLHYFFLAAFAWMCIEGIHLYLIVVGVIYN--KGFLHKNFY 534
Query: 704 CLGYGCPLIISVITIAVTQPSNTYKRKDVCWLNWSNGSKPLLAFVVPALAIVAVNFVVVL 763
GY P + V+ + Y VCWL+ N + +F+ PA I+ VN +
Sbjct: 535 IFGYLSPAV--VVGFSAALGYRYYGTTKVCWLSTENNF--IWSFIGPACLIILVNLLAFG 590
Query: 764 LVLTKLWRPTVGERLSRDDKATIIRVGKSLLILTPLLGLTWGFGIGTIVDSQNLAWHVIF 823
+++ K++R T G + I + L L LLG TW FG+ +V + ++ +F
Sbjct: 591 VIIYKVFRHTAGLKPEVSCFENIRSCARGALALLFLLGTTWIFGVLHVVHA-SVVTAYLF 649
Query: 824 ALLNAFQGFFILCFGILLDSKLRQ 847
+ NAFQG FI F +L K+++
Sbjct: 650 TVSNAFQGMFIFLFLCVLSRKIQE 673
>gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens]
Length = 1585
Score = 134 bits (336), Expect = 5e-31
Identities = 110/411 (26%), Positives = 178/411 (43%), Gaps = 67/411 (16%)
Query: 486 TLGNILPVSKNGNAQVNGPVISTV---IQNYSINEVFLFFSKIESNLSQPHCVFWDFSHL 542
TLG ILP + A + + TV Q + + + S I + + PHC WD+S
Sbjct: 823 TLGLILPPPRPPLAVTSRVMTVTVRPPTQPPAEPLITVELSYIINGTTDPHCASWDYSRA 882
Query: 543 Q-----WNDAGCHLVNETQDIVTCQCTHLTSFSILMSPFVPSTI----FPVVKWITYVGL 593
W+ C + CQC HL++F++L P T+ P V + +G
Sbjct: 883 DASSGDWDTENCQTLETQAAHTRCQCQHLSTFAVLAQPPKDLTLELAGSPSVPLV--IGC 940
Query: 594 GISIGSLILCLIIEALFWKQIKKSQTSHTRRICMVNIALSLLIADVWFIVGATVDTTVNP 653
+S +L+ L I A FW+ IK R I ++N LS+L +++ +VG + V
Sbjct: 941 AVSCMALLTLLAIYAAFWRFIKSE-----RSIILLNFCLSILASNILILVG---QSRVLS 992
Query: 654 SGVCTAAVFFTHFFYLSLFFWMLMLGILLAYRIILVFHHMAQHLMMAVGFCLGYGCPLII 713
GVCT F HFF+LS F W+L + V M L+ CLG+G P ++
Sbjct: 993 KGVCTMTAAFLHFFFLSSFCWVLTEA---WQSYLAVIGRMRTRLVRKRFLCLGWGLPALV 1049
Query: 714 SVITIAVTQPSNTYKRKDVCWLNWSNGSKPLLAFVVPALAIVAVNFVVVLLVLTKL---- 769
+++ T+ + Y CWL+ G L AFV PA IV VN ++ ++V KL
Sbjct: 1050 VAVSVGFTR-TKGYGTSSYCWLSLEGGL--LYAFVGPAAVIVLVNMLIGIIVFNKLMARD 1106
Query: 770 -----------------W--------------RPTVGERLSRDDKATIIRVGKSLLILTP 798
W P + +R+ A++ S ++ P
Sbjct: 1107 GISDKSKKQRAGSERCPWASLLLPCSACGAVPSPLLSSASARNAMASL----WSSCVVLP 1162
Query: 799 LLGLTWGFGIGTIVDSQNLAWHVIFALLNAFQGFFILCFGILLDSKLRQLL 849
LL LTW + + D +++ + +FA+ N+ QGF I L +++ ++
Sbjct: 1163 LLALTWMSAVLAMTDRRSVLFQALFAVFNSAQGFVITAVHCFLRREVQDVV 1213
>gi|4502359 brain-specific angiogenesis inhibitor 3 [Homo sapiens]
Length = 1522
Score = 130 bits (326), Expect = 7e-30
Identities = 140/623 (22%), Positives = 253/623 (40%), Gaps = 103/623 (16%)
Query: 285 AKCESSGWQVIRETCVLSLLEELNKNFSMIVGNATEAAVSSFVQNLSVIIRQNPSTTVGN 344
A+C S+ ++ ++ S+ E L K M+ G+ + + + Q + G+
Sbjct: 565 ARCISNEYRHLQH----SIKEHLAKGQRMLAGDGMSQVTKTLLD-----LTQRKNFYAGD 615
Query: 345 LASVVSILSNISSLSLASHFRVSNSTMEDVISIADNILNSASVTNWTVLLREEKYASS-R 403
L V IL N++ + + ++ +++ I N+L+ + W ++ Y S
Sbjct: 616 LLMSVEILRNVTDTFKRASYIPASDGVQNFFQIVSNLLDEENKEKWEDA--QQIYPGSIE 673
Query: 404 LLETLENISTLVPPTALPLNFSRKFIDWKGIPVNKSQL---------------KRGYSYQ 448
L++ +E+ +V + +F ++ + + +L ++G
Sbjct: 674 LMQVIEDFIHIVGMGMM--DFQNSYLMTGNVVASIQKLPAASVLTDINFPMKGRKGMVDW 731
Query: 449 IKMCPQNTSIPIRGRVLIGSDQFQRSLPETIISMASLTLGNILPVSKNGNAQVNGPVIST 508
+ IP + S + S + ++ L ILP +N + ++ T
Sbjct: 732 ARNSEDRVVIPKSIFTPVSSKELDESSVFVLGAVLYKNLDLILPTLRNYTVINSKIIVVT 791
Query: 509 VIQNYSINEVFLFF--SKIESNLSQPHCVFWDFSHLQ-----WNDAGCHLVNETQDIVTC 561
+ + FL + + + P+CV WD S W+ GC V C
Sbjct: 792 IRPEPKTTDSFLEIELAHLANGTLNPYCVLWDDSKTNESLGTWSTQGCKTVLTDASHTKC 851
Query: 562 QCTHLTSFSILMSP----FVPSTIFPVVKWITYVGLGISIGSLILCLIIEALFWKQIKKS 617
C L++F+IL + S+ P V I VG G+S +LI ++ A W+ I+
Sbjct: 852 LCDRLSTFAILAQQPREIIMESSGTPSVTLI--VGSGLSCLALITLAVVYAALWRYIRSE 909
Query: 618 QTSHTRRICMVNIALSLLIADVWFIVGATVDTTVNPSGVCTAAVFFTHFFYLSLFFWMLM 677
R I ++N LS++ +++ +VG T T N S +CT F HFF+L+ F W+L
Sbjct: 910 -----RSIILINFCLSIISSNILILVGQT--QTHNKS-ICTTTTAFLHFFFLASFCWVLT 961
Query: 678 LGILLAYRIILVFHHMAQHLMMAVGFCLGYGCPLIISVITIAVTQPSNTYKRKDVCWLNW 737
+ V + L+ CLG+G P ++ ++ T+ + Y CWL+
Sbjct: 962 EA---WQSYMAVTGKIRTRLIRKRFLCLGWGLPALVVATSVGFTR-TKGYGTDHYCWLSL 1017
Query: 738 SNGSKPLLAFVVPALAIVAVNFVVVLLVLTKLWRPTVGERLSRD---DKATIIRVGK--- 791
G L AFV PA A+V VN V+ +LV KL +SRD DK R G+
Sbjct: 1018 EGGL--LYAFVGPAAAVVLVNMVIGILVFNKL--------VSRDGILDKKLKHRAGQMSE 1067
Query: 792 ---------------------------------SLLILTPLLGLTWGFGIGTIVDSQNLA 818
S ++ PLL LTW + + D +++
Sbjct: 1068 PHSGLTLKCAKCGVVSTTALSATTASNAMASLWSSCVVLPLLALTWMSAVLAMTDKRSIL 1127
Query: 819 WHVIFALLNAFQGFFILCFGILL 841
+ ++FA+ ++ QGF I+ +L
Sbjct: 1128 FQILFAVFDSLQGFVIVMVHCIL 1150
>gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]
Length = 1474
Score = 125 bits (315), Expect = 1e-28
Identities = 123/518 (23%), Positives = 232/518 (44%), Gaps = 57/518 (11%)
Query: 365 RVSNSTMEDVISIADNILNSASVTNWTVL-LREEKYASSRLLETLENISTLVPPTALPLN 423
R ++ V+ DN+L ++ +W + E+ + ++ LL+ LE + L+ +
Sbjct: 611 RTCKDYIKAVVETVDNLLRPEALESWKDMNATEQVHTATMLLDVLEEGAFLLADN---VR 667
Query: 424 FSRKFIDWK-GIPVNKSQLKRGYSYQIKMCPQNTSIPIRGRVLIGSDQFQRSLPETIISM 482
+F+ K + + + L Q + PQ P + + + + +++ ++ +
Sbjct: 668 EPARFLAAKENVVLEVTVLNTEGQVQELVFPQE-EYPRKNSIQLSAKTIKQNSRNGVVKV 726
Query: 483 ASLTLGNI--------LPVSKNGNAQVNGP-----VISTVIQNYSINE----VFLFFSKI 525
+ N+ V G A GP V+++ + SIN+ VFL I
Sbjct: 727 VFILYNNLGLFLSTENATVKLAGEAGPGGPGGASLVVNSQVIAASINKESSRVFLMDPVI 786
Query: 526 -------ESNLSQPHCVFWDFSHLQ----WNDAGCHLVNETQDIVTCQCTHLTSFSILMS 574
+ N +C FW++S W+ GC LV + TC C+HLT+F++LM+
Sbjct: 787 FTVAHLEDKNHFNANCSFWNYSERSMLGYWSTQGCRLVESNKTHTTCACSHLTNFAVLMA 846
Query: 575 P---FVPSTIFPVVKWITYVGLGISIGSLILCLIIEALFWKQIKKSQTSHTRRICMVNIA 631
+ ++ IT+VG+ IS+ L +C I F + ++ + + + +C
Sbjct: 847 HREIYQGRINELLLSVITWVGIVISLVCLAIC-ISTFCFLRGLQTDRNTIHKNLC----- 900
Query: 632 LSLLIADVWFIVGATVDTTVNPSGVCTAAVFFTHFFYLSLFFWMLMLGILLAYRIILVFH 691
++L +A++ F+VG +D T C H+F+L+ F W+ + G+ L ++ VF
Sbjct: 901 INLFLAELLFLVG--IDKT-QYEIACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFE 957
Query: 692 HMAQHLMMAVGFCLGYGCPLIISVITIAVTQPSNTYKRKDVCWLNWSNGSKPLLAFVVPA 751
+++ + GY P + V+ IA +Y + CWL N + +F+ P
Sbjct: 958 --SEYSRTKYYYLGGYCFPAL--VVGIAAAIDYRSYGTEKACWLRVDNYF--IWSFIGPV 1011
Query: 752 LAIVAVNFVVVLLVLTKLWRPT--VGERLSRDDKATIIRVGKSLLILTPLLGLTWGFGIG 809
++ VN V +++ L K+ R + + SR D +G L+ LLGLTW FG+
Sbjct: 1012 SFVIVVNLVFLMVTLHKMIRSSSVLKPDSSRLDNIKSWALGAIALLF--LLGLTWAFGL- 1068
Query: 810 TIVDSQNLAWHVIFALLNAFQGFFILCFGILLDSKLRQ 847
++ +++ +F NAFQG FI F L K+ +
Sbjct: 1069 LFINKESVVMAYLFTTFNAFQGVFIFVFHCALQKKVHK 1106
>gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]
Length = 1469
Score = 125 bits (315), Expect = 1e-28
Identities = 123/518 (23%), Positives = 232/518 (44%), Gaps = 57/518 (11%)
Query: 365 RVSNSTMEDVISIADNILNSASVTNWTVL-LREEKYASSRLLETLENISTLVPPTALPLN 423
R ++ V+ DN+L ++ +W + E+ + ++ LL+ LE + L+ +
Sbjct: 606 RTCKDYIKAVVETVDNLLRPEALESWKDMNATEQVHTATMLLDVLEEGAFLLADN---VR 662
Query: 424 FSRKFIDWK-GIPVNKSQLKRGYSYQIKMCPQNTSIPIRGRVLIGSDQFQRSLPETIISM 482
+F+ K + + + L Q + PQ P + + + + +++ ++ +
Sbjct: 663 EPARFLAAKENVVLEVTVLNTEGQVQELVFPQE-EYPRKNSIQLSAKTIKQNSRNGVVKV 721
Query: 483 ASLTLGNI--------LPVSKNGNAQVNGP-----VISTVIQNYSINE----VFLFFSKI 525
+ N+ V G A GP V+++ + SIN+ VFL I
Sbjct: 722 VFILYNNLGLFLSTENATVKLAGEAGPGGPGGASLVVNSQVIAASINKESSRVFLMDPVI 781
Query: 526 -------ESNLSQPHCVFWDFSHLQ----WNDAGCHLVNETQDIVTCQCTHLTSFSILMS 574
+ N +C FW++S W+ GC LV + TC C+HLT+F++LM+
Sbjct: 782 FTVAHLEDKNHFNANCSFWNYSERSMLGYWSTQGCRLVESNKTHTTCACSHLTNFAVLMA 841
Query: 575 P---FVPSTIFPVVKWITYVGLGISIGSLILCLIIEALFWKQIKKSQTSHTRRICMVNIA 631
+ ++ IT+VG+ IS+ L +C I F + ++ + + + +C
Sbjct: 842 HREIYQGRINELLLSVITWVGIVISLVCLAIC-ISTFCFLRGLQTDRNTIHKNLC----- 895
Query: 632 LSLLIADVWFIVGATVDTTVNPSGVCTAAVFFTHFFYLSLFFWMLMLGILLAYRIILVFH 691
++L +A++ F+VG +D T C H+F+L+ F W+ + G+ L ++ VF
Sbjct: 896 INLFLAELLFLVG--IDKT-QYEIACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFE 952
Query: 692 HMAQHLMMAVGFCLGYGCPLIISVITIAVTQPSNTYKRKDVCWLNWSNGSKPLLAFVVPA 751
+++ + GY P + V+ IA +Y + CWL N + +F+ P
Sbjct: 953 --SEYSRTKYYYLGGYCFPAL--VVGIAAAIDYRSYGTEKACWLRVDNYF--IWSFIGPV 1006
Query: 752 LAIVAVNFVVVLLVLTKLWRPT--VGERLSRDDKATIIRVGKSLLILTPLLGLTWGFGIG 809
++ VN V +++ L K+ R + + SR D +G L+ LLGLTW FG+
Sbjct: 1007 SFVIVVNLVFLMVTLHKMIRSSSVLKPDSSRLDNIKSWALGAIALLF--LLGLTWAFGL- 1063
Query: 810 TIVDSQNLAWHVIFALLNAFQGFFILCFGILLDSKLRQ 847
++ +++ +F NAFQG FI F L K+ +
Sbjct: 1064 LFINKESVVMAYLFTTFNAFQGVFIFVFHCALQKKVHK 1101
>gi|74048357 G protein-coupled receptor 126 alpha 1 precursor [Homo
sapiens]
Length = 1221
Score = 125 bits (314), Expect = 2e-28
Identities = 152/617 (24%), Positives = 271/617 (43%), Gaps = 95/617 (15%)
Query: 270 EYTLPCSS--GYRG------NITAKCESSGWQVIRETCVLSLLEELNKNFSMIVG--NAT 319
EY LPC G+ N T + V C+ E N+ ++ N T
Sbjct: 543 EYVLPCPDKPGFSASRICFYNATNPLVTYWGPVDISNCLKEANEVANQILNLTADGQNLT 602
Query: 320 EAAVSSFVQNLSVIIRQNPSTTVGNLASVVSILSNISSLSLASHFRVSNSTMEDVISIAD 379
A +++ V+ + I+ + + + +++++I SNI S S + S+ ++ + +A
Sbjct: 603 SANITNIVEQVKRIVNKEENIDITLGSTLMNIFSNILSSSDSDLLESSSEALKTIDELAF 662
Query: 380 NI-LNSASVTNWTVLLREEKYASSRLLETLENISTLVPPTALPLNFSRKFIDWKGIPVNK 438
I LNS S N T +R L ++S+L+P T NFS G+P N
Sbjct: 663 KIDLNSTSHVNIT----------TRNLAL--SVSSLLPGTNAISNFSI------GLPSNN 704
Query: 439 SQLKRGYSYQIKMCPQNTSIPIRGRVLIGSDQFQRSLPE--TIISMASLTLGNILPVSKN 496
SY +M ++ + V++ + + PE ++ A T N K
Sbjct: 705 E------SY-FQMDFESGQVDPLASVILPPNLLENLSPEDSVLVRRAQFTFFN-----KT 752
Query: 497 GNAQVNGPVISTVIQNY---SINEVFL------FFSKIESNLSQ----PHCVFWDFSHLQ 543
G Q GP T++ SI + + KI+ +Q P C FWD + +
Sbjct: 753 GLFQDVGPQRKTLVSYVMACSIGNITIQNLKDPVQIKIKHTRTQEVHHPICAFWDLNKNK 812
Query: 544 ----WNDAGC--HLVNETQDIVTCQCTHLTSFSILMS-PFVPSTI----FPVVKWITYVG 592
WN +GC H ++ + V C C H T F +LM P S + V+ +I+Y+G
Sbjct: 813 SFGGWNTSGCVAHRDSDASETV-CLCNHFTHFGVLMDLPRSASQLDARNTKVLTFISYIG 871
Query: 593 LGISIGSLILCLIIEALFWKQIKKSQTSHTRRICMVNIALSLLIADVWFIVGATVDTTVN 652
GIS L+ F +K + + +I M N++ +LL ++ F++ + T+ N
Sbjct: 872 CGISAIFSAATLLTYVAF----EKLRRDYPSKILM-NLSTALLFLNLLFLLDGWI-TSFN 925
Query: 653 PSGVCTAAVFFTHFFYLSLFFWMLMLGILLAYRIILVFHHMAQHLMMAVGFC-LGYGCPL 711
G+C A HFF L+ F WM + I + ++ VF+ + ++ FC +G+G P
Sbjct: 926 VDGLCIAVAVLLHFFLLATFTWMGLEAIHMYIALVKVFNTYIRRYILK--FCIIGWGLPA 983
Query: 712 IISVITIAVTQPSNTY--------KRKDVCWLNWSNGSKPLLAFVVPA---LAIVAVNFV 760
++ + +A + Y K + CW+ P++ +V A + +N
Sbjct: 984 LVVSVVLASRNNNEVYGKESYGKEKGDEFCWI-----QDPVIFYVTCAGYFGVMFFLNIA 1038
Query: 761 VVLLVLTKLWRPTVGERLSRDDKATIIRVGKSLLILTPLLGLTWGFGIGTIVDSQNLAWH 820
+ ++V+ ++ G+R +R + ++R +S++ LT LLG+TWGF N+ +
Sbjct: 1039 MFIVVMVQICGRN-GKRSNRTLREEVLRNLRSVVSLTFLLGMTWGFAF-FAWGPLNIPFM 1096
Query: 821 VIFALLNAFQGFFILCF 837
+F++ N+ QG FI F
Sbjct: 1097 YLFSIFNSLQGLFIFIF 1113
>gi|50355941 G protein-coupled receptor 126 beta 1 precursor [Homo
sapiens]
Length = 1250
Score = 125 bits (314), Expect = 2e-28
Identities = 152/617 (24%), Positives = 271/617 (43%), Gaps = 95/617 (15%)
Query: 270 EYTLPCSS--GYRG------NITAKCESSGWQVIRETCVLSLLEELNKNFSMIVG--NAT 319
EY LPC G+ N T + V C+ E N+ ++ N T
Sbjct: 543 EYVLPCPDKPGFSASRICFYNATNPLVTYWGPVDISNCLKEANEVANQILNLTADGQNLT 602
Query: 320 EAAVSSFVQNLSVIIRQNPSTTVGNLASVVSILSNISSLSLASHFRVSNSTMEDVISIAD 379
A +++ V+ + I+ + + + +++++I SNI S S + S+ ++ + +A
Sbjct: 603 SANITNIVEQVKRIVNKEENIDITLGSTLMNIFSNILSSSDSDLLESSSEALKTIDELAF 662
Query: 380 NI-LNSASVTNWTVLLREEKYASSRLLETLENISTLVPPTALPLNFSRKFIDWKGIPVNK 438
I LNS S N T +R L ++S+L+P T NFS G+P N
Sbjct: 663 KIDLNSTSHVNIT----------TRNLAL--SVSSLLPGTNAISNFSI------GLPSNN 704
Query: 439 SQLKRGYSYQIKMCPQNTSIPIRGRVLIGSDQFQRSLPE--TIISMASLTLGNILPVSKN 496
SY +M ++ + V++ + + PE ++ A T N K
Sbjct: 705 E------SY-FQMDFESGQVDPLASVILPPNLLENLSPEDSVLVRRAQFTFFN-----KT 752
Query: 497 GNAQVNGPVISTVIQNY---SINEVFL------FFSKIESNLSQ----PHCVFWDFSHLQ 543
G Q GP T++ SI + + KI+ +Q P C FWD + +
Sbjct: 753 GLFQDVGPQRKTLVSYVMACSIGNITIQNLKDPVQIKIKHTRTQEVHHPICAFWDLNKNK 812
Query: 544 ----WNDAGC--HLVNETQDIVTCQCTHLTSFSILMS-PFVPSTI----FPVVKWITYVG 592
WN +GC H ++ + V C C H T F +LM P S + V+ +I+Y+G
Sbjct: 813 SFGGWNTSGCVAHRDSDASETV-CLCNHFTHFGVLMDLPRSASQLDARNTKVLTFISYIG 871
Query: 593 LGISIGSLILCLIIEALFWKQIKKSQTSHTRRICMVNIALSLLIADVWFIVGATVDTTVN 652
GIS L+ F +K + + +I M N++ +LL ++ F++ + T+ N
Sbjct: 872 CGISAIFSAATLLTYVAF----EKLRRDYPSKILM-NLSTALLFLNLLFLLDGWI-TSFN 925
Query: 653 PSGVCTAAVFFTHFFYLSLFFWMLMLGILLAYRIILVFHHMAQHLMMAVGFC-LGYGCPL 711
G+C A HFF L+ F WM + I + ++ VF+ + ++ FC +G+G P
Sbjct: 926 VDGLCIAVAVLLHFFLLATFTWMGLEAIHMYIALVKVFNTYIRRYILK--FCIIGWGLPA 983
Query: 712 IISVITIAVTQPSNTY--------KRKDVCWLNWSNGSKPLLAFVVPA---LAIVAVNFV 760
++ + +A + Y K + CW+ P++ +V A + +N
Sbjct: 984 LVVSVVLASRNNNEVYGKESYGKEKGDEFCWI-----QDPVIFYVTCAGYFGVMFFLNIA 1038
Query: 761 VVLLVLTKLWRPTVGERLSRDDKATIIRVGKSLLILTPLLGLTWGFGIGTIVDSQNLAWH 820
+ ++V+ ++ G+R +R + ++R +S++ LT LLG+TWGF N+ +
Sbjct: 1039 MFIVVMVQICGRN-GKRSNRTLREEVLRNLRSVVSLTFLLGMTWGFAF-FAWGPLNIPFM 1096
Query: 821 VIFALLNAFQGFFILCF 837
+F++ N+ QG FI F
Sbjct: 1097 YLFSIFNSLQGLFIFIF 1113
>gi|74048422 G protein-coupled receptor 126 alpha 2 precursor [Homo
sapiens]
Length = 1193
Score = 125 bits (314), Expect = 2e-28
Identities = 152/617 (24%), Positives = 271/617 (43%), Gaps = 95/617 (15%)
Query: 270 EYTLPCSS--GYRG------NITAKCESSGWQVIRETCVLSLLEELNKNFSMIVG--NAT 319
EY LPC G+ N T + V C+ E N+ ++ N T
Sbjct: 515 EYVLPCPDKPGFSASRICFYNATNPLVTYWGPVDISNCLKEANEVANQILNLTADGQNLT 574
Query: 320 EAAVSSFVQNLSVIIRQNPSTTVGNLASVVSILSNISSLSLASHFRVSNSTMEDVISIAD 379
A +++ V+ + I+ + + + +++++I SNI S S + S+ ++ + +A
Sbjct: 575 SANITNIVEQVKRIVNKEENIDITLGSTLMNIFSNILSSSDSDLLESSSEALKTIDELAF 634
Query: 380 NI-LNSASVTNWTVLLREEKYASSRLLETLENISTLVPPTALPLNFSRKFIDWKGIPVNK 438
I LNS S N T +R L ++S+L+P T NFS G+P N
Sbjct: 635 KIDLNSTSHVNIT----------TRNLAL--SVSSLLPGTNAISNFSI------GLPSNN 676
Query: 439 SQLKRGYSYQIKMCPQNTSIPIRGRVLIGSDQFQRSLPE--TIISMASLTLGNILPVSKN 496
SY +M ++ + V++ + + PE ++ A T N K
Sbjct: 677 E------SY-FQMDFESGQVDPLASVILPPNLLENLSPEDSVLVRRAQFTFFN-----KT 724
Query: 497 GNAQVNGPVISTVIQNY---SINEVFL------FFSKIESNLSQ----PHCVFWDFSHLQ 543
G Q GP T++ SI + + KI+ +Q P C FWD + +
Sbjct: 725 GLFQDVGPQRKTLVSYVMACSIGNITIQNLKDPVQIKIKHTRTQEVHHPICAFWDLNKNK 784
Query: 544 ----WNDAGC--HLVNETQDIVTCQCTHLTSFSILMS-PFVPSTI----FPVVKWITYVG 592
WN +GC H ++ + V C C H T F +LM P S + V+ +I+Y+G
Sbjct: 785 SFGGWNTSGCVAHRDSDASETV-CLCNHFTHFGVLMDLPRSASQLDARNTKVLTFISYIG 843
Query: 593 LGISIGSLILCLIIEALFWKQIKKSQTSHTRRICMVNIALSLLIADVWFIVGATVDTTVN 652
GIS L+ F +K + + +I M N++ +LL ++ F++ + T+ N
Sbjct: 844 CGISAIFSAATLLTYVAF----EKLRRDYPSKILM-NLSTALLFLNLLFLLDGWI-TSFN 897
Query: 653 PSGVCTAAVFFTHFFYLSLFFWMLMLGILLAYRIILVFHHMAQHLMMAVGFC-LGYGCPL 711
G+C A HFF L+ F WM + I + ++ VF+ + ++ FC +G+G P
Sbjct: 898 VDGLCIAVAVLLHFFLLATFTWMGLEAIHMYIALVKVFNTYIRRYILK--FCIIGWGLPA 955
Query: 712 IISVITIAVTQPSNTY--------KRKDVCWLNWSNGSKPLLAFVVPA---LAIVAVNFV 760
++ + +A + Y K + CW+ P++ +V A + +N
Sbjct: 956 LVVSVVLASRNNNEVYGKESYGKEKGDEFCWI-----QDPVIFYVTCAGYFGVMFFLNIA 1010
Query: 761 VVLLVLTKLWRPTVGERLSRDDKATIIRVGKSLLILTPLLGLTWGFGIGTIVDSQNLAWH 820
+ ++V+ ++ G+R +R + ++R +S++ LT LLG+TWGF N+ +
Sbjct: 1011 MFIVVMVQICGRN-GKRSNRTLREEVLRNLRSVVSLTFLLGMTWGFAF-FAWGPLNIPFM 1068
Query: 821 VIFALLNAFQGFFILCF 837
+F++ N+ QG FI F
Sbjct: 1069 YLFSIFNSLQGLFIFIF 1085
>gi|74048403 G protein-coupled receptor 126 beta 2 precursor [Homo
sapiens]
Length = 1222
Score = 125 bits (314), Expect = 2e-28
Identities = 152/617 (24%), Positives = 271/617 (43%), Gaps = 95/617 (15%)
Query: 270 EYTLPCSS--GYRG------NITAKCESSGWQVIRETCVLSLLEELNKNFSMIVG--NAT 319
EY LPC G+ N T + V C+ E N+ ++ N T
Sbjct: 515 EYVLPCPDKPGFSASRICFYNATNPLVTYWGPVDISNCLKEANEVANQILNLTADGQNLT 574
Query: 320 EAAVSSFVQNLSVIIRQNPSTTVGNLASVVSILSNISSLSLASHFRVSNSTMEDVISIAD 379
A +++ V+ + I+ + + + +++++I SNI S S + S+ ++ + +A
Sbjct: 575 SANITNIVEQVKRIVNKEENIDITLGSTLMNIFSNILSSSDSDLLESSSEALKTIDELAF 634
Query: 380 NI-LNSASVTNWTVLLREEKYASSRLLETLENISTLVPPTALPLNFSRKFIDWKGIPVNK 438
I LNS S N T +R L ++S+L+P T NFS G+P N
Sbjct: 635 KIDLNSTSHVNIT----------TRNLAL--SVSSLLPGTNAISNFSI------GLPSNN 676
Query: 439 SQLKRGYSYQIKMCPQNTSIPIRGRVLIGSDQFQRSLPE--TIISMASLTLGNILPVSKN 496
SY +M ++ + V++ + + PE ++ A T N K
Sbjct: 677 E------SY-FQMDFESGQVDPLASVILPPNLLENLSPEDSVLVRRAQFTFFN-----KT 724
Query: 497 GNAQVNGPVISTVIQNY---SINEVFL------FFSKIESNLSQ----PHCVFWDFSHLQ 543
G Q GP T++ SI + + KI+ +Q P C FWD + +
Sbjct: 725 GLFQDVGPQRKTLVSYVMACSIGNITIQNLKDPVQIKIKHTRTQEVHHPICAFWDLNKNK 784
Query: 544 ----WNDAGC--HLVNETQDIVTCQCTHLTSFSILMS-PFVPSTI----FPVVKWITYVG 592
WN +GC H ++ + V C C H T F +LM P S + V+ +I+Y+G
Sbjct: 785 SFGGWNTSGCVAHRDSDASETV-CLCNHFTHFGVLMDLPRSASQLDARNTKVLTFISYIG 843
Query: 593 LGISIGSLILCLIIEALFWKQIKKSQTSHTRRICMVNIALSLLIADVWFIVGATVDTTVN 652
GIS L+ F +K + + +I M N++ +LL ++ F++ + T+ N
Sbjct: 844 CGISAIFSAATLLTYVAF----EKLRRDYPSKILM-NLSTALLFLNLLFLLDGWI-TSFN 897
Query: 653 PSGVCTAAVFFTHFFYLSLFFWMLMLGILLAYRIILVFHHMAQHLMMAVGFC-LGYGCPL 711
G+C A HFF L+ F WM + I + ++ VF+ + ++ FC +G+G P
Sbjct: 898 VDGLCIAVAVLLHFFLLATFTWMGLEAIHMYIALVKVFNTYIRRYILK--FCIIGWGLPA 955
Query: 712 IISVITIAVTQPSNTY--------KRKDVCWLNWSNGSKPLLAFVVPA---LAIVAVNFV 760
++ + +A + Y K + CW+ P++ +V A + +N
Sbjct: 956 LVVSVVLASRNNNEVYGKESYGKEKGDEFCWI-----QDPVIFYVTCAGYFGVMFFLNIA 1010
Query: 761 VVLLVLTKLWRPTVGERLSRDDKATIIRVGKSLLILTPLLGLTWGFGIGTIVDSQNLAWH 820
+ ++V+ ++ G+R +R + ++R +S++ LT LLG+TWGF N+ +
Sbjct: 1011 MFIVVMVQICGRN-GKRSNRTLREEVLRNLRSVVSLTFLLGMTWGFAF-FAWGPLNIPFM 1068
Query: 821 VIFALLNAFQGFFILCF 837
+F++ N+ QG FI F
Sbjct: 1069 YLFSIFNSLQGLFIFIF 1085
>gi|59710093 G-protein coupled receptor 112 [Homo sapiens]
Length = 3080
Score = 125 bits (314), Expect = 2e-28
Identities = 99/356 (27%), Positives = 165/356 (46%), Gaps = 27/356 (7%)
Query: 528 NLSQPHCVFWDFSHLQ----WNDAGCHLVNETQDIVTCQCTHLTSFSILMS---PFVPST 580
N Q HC FWDF + WN +GC + + CQC HLT F +LM V S
Sbjct: 2679 NYGQVHCAFWDFENNNGLGGWNSSGCKVKETNVNYTICQCDHLTHFGVLMDLSRSTVDSV 2738
Query: 581 IFPVVKWITYVGLGISIGSLILCLIIEALFWKQIKKSQTSHTRRICMVNIALSLLIADVW 640
++ ITY G GIS L + ++ F K K ++N+ +LL+ ++
Sbjct: 2739 NEQILALITYTGCGISSIFLGVAVVTYIAFHKLRKDYPAK-----ILINLCTALLMLNLV 2793
Query: 641 FIVGATVDTTVNPSGVCTAAVFFTHFFYLSLFFWMLMLGILLAYRIILVFHHMAQHLMMA 700
F++ + + ++ GVC A H+F L F WM + + + ++ VF+ + ++
Sbjct: 2794 FLINSWL-SSFQKVGVCITAAVALHYFLLVSFTWMGLEAVHMYLALVKVFNIYIPNYILK 2852
Query: 701 VGFCL-GYGCPLIISVITIAVTQP--SNTYKRKDVCWLNWSNGSKPLLAFVVPALAIVAV 757
FCL G+G P I+ IT++V + CW+ + S ++ V I +
Sbjct: 2853 --FCLVGWGIPAIMVAITVSVKKDLYGTLSPTTPFCWI--KDDSIFYISVVAYFCLIFLM 2908
Query: 758 NFVVVLLVLTKLWRPTVGERLSRDDKATIIRVGKSLLILTPLLGLTWGFGIGTIVDSQNL 817
N + VL +L +V ++ + + I+ K + LT LLGLTWGF +N
Sbjct: 2909 NLSMFCTVLVQL--NSVKSQIQKTRRKMILHDLKGTMSLTFLLGLTWGFAFFAWGPMRNF 2966
Query: 818 AWHVIFALLNAFQGFFILCFGILLDSKLRQLLFNKLSALSSWKQTEKQNSSDLSAK 873
+ +FA+ N QGFFI F ++ +R+ ++ W + + NSSD S++
Sbjct: 2967 FLY-LFAIFNTLQGFFIFVFHCVMKESVREQW--QIHLCCGWLRLD--NSSDGSSR 3017
>gi|23397681 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform a [Homo sapiens]
Length = 823
Score = 123 bits (308), Expect = 9e-28
Identities = 104/380 (27%), Positives = 169/380 (44%), Gaps = 30/380 (7%)
Query: 511 QNYSINEVFLFFSKIESNLSQPHCVFWDFSHL---QWNDAGCHLVNETQDIVTCQCTHLT 567
QN S F F + + CVFW+ W GC + C+CTHL+
Sbjct: 459 QNLSSPVTFTFSHRSVIPRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLS 518
Query: 568 SFSILMSPFVPSTIFPVVKWITYVGLGISIGSLILCLIIEALFWKQIKKSQTSHTRRICM 627
SF++LM+ + PV+ ITY+GL +S +LCL++ AL + K Q + T
Sbjct: 519 SFAVLMAHYDVQEEDPVLTVITYMGLSVS----LLCLLLAALTFLLCKAIQNTSTS--LH 572
Query: 628 VNIALSLLIADVWFIVGATVDTTVNPSGVCTAAVFFTHFFYLSLFFWMLMLGI---LLAY 684
+ ++L L +A + F+V +D T +C+ H+ YL+ WML+ + L A
Sbjct: 573 LQLSLCLFLAHLLFLV--AIDQT-GHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTAR 629
Query: 685 RIILVFHHMAQHLMMAVGFCLGYGCPLIISVITIAVTQPSNTYKRKDVCWLNWSNGSKPL 744
+ +V + M + F +GYG P + + I+ + Y CWL G +
Sbjct: 630 NLTVVNYSSINRFMKKLMFPVGYGVPAV--TVAISAASRPHLYGTPSRCWLQPEKGF--I 685
Query: 745 LAFVVPALAIVAVNFVVVLLVLTKLWRPTVGERLSR-DDKATIIRVGKSLLILTP----L 799
F+ P AI +VN V L L LW + RLS + + + +R + L +
Sbjct: 686 WGFLGPVCAIFSVNLV---LFLVTLW--ILKNRLSSLNSEVSTLRNTRMLAFKATAQLFI 740
Query: 800 LGLTWGFGIGTIVDSQNLAWHVIFALLNAFQGFFILCFGILLDSKLRQLLFNKLSALSSW 859
LG TW GI + + + + +F ++N+ QG FI LL ++R+ +
Sbjct: 741 LGCTWCLGILQVGPAARVMAY-LFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKL 799
Query: 860 KQTEKQNSSDLSAKPKFSKP 879
K + ++ SAK SKP
Sbjct: 800 KTESEMHTLSSSAKADTSKP 819
>gi|23397693 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform g [Homo sapiens]
Length = 719
Score = 123 bits (308), Expect = 9e-28
Identities = 104/380 (27%), Positives = 169/380 (44%), Gaps = 30/380 (7%)
Query: 511 QNYSINEVFLFFSKIESNLSQPHCVFWDFSHL---QWNDAGCHLVNETQDIVTCQCTHLT 567
QN S F F + + CVFW+ W GC + C+CTHL+
Sbjct: 355 QNLSSPVTFTFSHRSVIPRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLS 414
Query: 568 SFSILMSPFVPSTIFPVVKWITYVGLGISIGSLILCLIIEALFWKQIKKSQTSHTRRICM 627
SF++LM+ + PV+ ITY+GL +S +LCL++ AL + K Q + T
Sbjct: 415 SFAVLMAHYDVQEEDPVLTVITYMGLSVS----LLCLLLAALTFLLCKAIQNTSTS--LH 468
Query: 628 VNIALSLLIADVWFIVGATVDTTVNPSGVCTAAVFFTHFFYLSLFFWMLMLGI---LLAY 684
+ ++L L +A + F+V +D T +C+ H+ YL+ WML+ + L A
Sbjct: 469 LQLSLCLFLAHLLFLV--AIDQT-GHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTAR 525
Query: 685 RIILVFHHMAQHLMMAVGFCLGYGCPLIISVITIAVTQPSNTYKRKDVCWLNWSNGSKPL 744
+ +V + M + F +GYG P + + I+ + Y CWL G +
Sbjct: 526 NLTVVNYSSINRFMKKLMFPVGYGVPAV--TVAISAASRPHLYGTPSRCWLQPEKGF--I 581
Query: 745 LAFVVPALAIVAVNFVVVLLVLTKLWRPTVGERLSR-DDKATIIRVGKSLLILTP----L 799
F+ P AI +VN V L L LW + RLS + + + +R + L +
Sbjct: 582 WGFLGPVCAIFSVNLV---LFLVTLW--ILKNRLSSLNSEVSTLRNTRMLAFKATAQLFI 636
Query: 800 LGLTWGFGIGTIVDSQNLAWHVIFALLNAFQGFFILCFGILLDSKLRQLLFNKLSALSSW 859
LG TW GI + + + + +F ++N+ QG FI LL ++R+ +
Sbjct: 637 LGCTWCLGILQVGPAARVMAY-LFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKL 695
Query: 860 KQTEKQNSSDLSAKPKFSKP 879
K + ++ SAK SKP
Sbjct: 696 KTESEMHTLSSSAKADTSKP 715
>gi|23397691 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform f [Homo sapiens]
Length = 763
Score = 123 bits (308), Expect = 9e-28
Identities = 104/380 (27%), Positives = 169/380 (44%), Gaps = 30/380 (7%)
Query: 511 QNYSINEVFLFFSKIESNLSQPHCVFWDFSHL---QWNDAGCHLVNETQDIVTCQCTHLT 567
QN S F F + + CVFW+ W GC + C+CTHL+
Sbjct: 399 QNLSSPVTFTFSHRSVIPRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLS 458
Query: 568 SFSILMSPFVPSTIFPVVKWITYVGLGISIGSLILCLIIEALFWKQIKKSQTSHTRRICM 627
SF++LM+ + PV+ ITY+GL +S +LCL++ AL + K Q + T
Sbjct: 459 SFAVLMAHYDVQEEDPVLTVITYMGLSVS----LLCLLLAALTFLLCKAIQNTSTS--LH 512
Query: 628 VNIALSLLIADVWFIVGATVDTTVNPSGVCTAAVFFTHFFYLSLFFWMLMLGI---LLAY 684
+ ++L L +A + F+V +D T +C+ H+ YL+ WML+ + L A
Sbjct: 513 LQLSLCLFLAHLLFLV--AIDQT-GHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTAR 569
Query: 685 RIILVFHHMAQHLMMAVGFCLGYGCPLIISVITIAVTQPSNTYKRKDVCWLNWSNGSKPL 744
+ +V + M + F +GYG P + + I+ + Y CWL G +
Sbjct: 570 NLTVVNYSSINRFMKKLMFPVGYGVPAV--TVAISAASRPHLYGTPSRCWLQPEKGF--I 625
Query: 745 LAFVVPALAIVAVNFVVVLLVLTKLWRPTVGERLSR-DDKATIIRVGKSLLILTP----L 799
F+ P AI +VN V L L LW + RLS + + + +R + L +
Sbjct: 626 WGFLGPVCAIFSVNLV---LFLVTLW--ILKNRLSSLNSEVSTLRNTRMLAFKATAQLFI 680
Query: 800 LGLTWGFGIGTIVDSQNLAWHVIFALLNAFQGFFILCFGILLDSKLRQLLFNKLSALSSW 859
LG TW GI + + + + +F ++N+ QG FI LL ++R+ +
Sbjct: 681 LGCTWCLGILQVGPAARVMAY-LFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKL 739
Query: 860 KQTEKQNSSDLSAKPKFSKP 879
K + ++ SAK SKP
Sbjct: 740 KTESEMHTLSSSAKADTSKP 759
>gi|23397689 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform e [Homo sapiens]
Length = 812
Score = 123 bits (308), Expect = 9e-28
Identities = 104/380 (27%), Positives = 169/380 (44%), Gaps = 30/380 (7%)
Query: 511 QNYSINEVFLFFSKIESNLSQPHCVFWDFSHL---QWNDAGCHLVNETQDIVTCQCTHLT 567
QN S F F + + CVFW+ W GC + C+CTHL+
Sbjct: 448 QNLSSPVTFTFSHRSVIPRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLS 507
Query: 568 SFSILMSPFVPSTIFPVVKWITYVGLGISIGSLILCLIIEALFWKQIKKSQTSHTRRICM 627
SF++LM+ + PV+ ITY+GL +S +LCL++ AL + K Q + T
Sbjct: 508 SFAVLMAHYDVQEEDPVLTVITYMGLSVS----LLCLLLAALTFLLCKAIQNTSTS--LH 561
Query: 628 VNIALSLLIADVWFIVGATVDTTVNPSGVCTAAVFFTHFFYLSLFFWMLMLGI---LLAY 684
+ ++L L +A + F+V +D T +C+ H+ YL+ WML+ + L A
Sbjct: 562 LQLSLCLFLAHLLFLV--AIDQT-GHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTAR 618
Query: 685 RIILVFHHMAQHLMMAVGFCLGYGCPLIISVITIAVTQPSNTYKRKDVCWLNWSNGSKPL 744
+ +V + M + F +GYG P + + I+ + Y CWL G +
Sbjct: 619 NLTVVNYSSINRFMKKLMFPVGYGVPAV--TVAISAASRPHLYGTPSRCWLQPEKGF--I 674
Query: 745 LAFVVPALAIVAVNFVVVLLVLTKLWRPTVGERLSR-DDKATIIRVGKSLLILTP----L 799
F+ P AI +VN V L L LW + RLS + + + +R + L +
Sbjct: 675 WGFLGPVCAIFSVNLV---LFLVTLW--ILKNRLSSLNSEVSTLRNTRMLAFKATAQLFI 729
Query: 800 LGLTWGFGIGTIVDSQNLAWHVIFALLNAFQGFFILCFGILLDSKLRQLLFNKLSALSSW 859
LG TW GI + + + + +F ++N+ QG FI LL ++R+ +
Sbjct: 730 LGCTWCLGILQVGPAARVMAY-LFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKL 788
Query: 860 KQTEKQNSSDLSAKPKFSKP 879
K + ++ SAK SKP
Sbjct: 789 KTESEMHTLSSSAKADTSKP 808
>gi|23397687 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform d [Homo sapiens]
Length = 681
Score = 123 bits (308), Expect = 9e-28
Identities = 104/380 (27%), Positives = 169/380 (44%), Gaps = 30/380 (7%)
Query: 511 QNYSINEVFLFFSKIESNLSQPHCVFWDFSHL---QWNDAGCHLVNETQDIVTCQCTHLT 567
QN S F F + + CVFW+ W GC + C+CTHL+
Sbjct: 317 QNLSSPVTFTFSHRSVIPRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLS 376
Query: 568 SFSILMSPFVPSTIFPVVKWITYVGLGISIGSLILCLIIEALFWKQIKKSQTSHTRRICM 627
SF++LM+ + PV+ ITY+GL +S +LCL++ AL + K Q + T
Sbjct: 377 SFAVLMAHYDVQEEDPVLTVITYMGLSVS----LLCLLLAALTFLLCKAIQNTSTS--LH 430
Query: 628 VNIALSLLIADVWFIVGATVDTTVNPSGVCTAAVFFTHFFYLSLFFWMLMLGI---LLAY 684
+ ++L L +A + F+V +D T +C+ H+ YL+ WML+ + L A
Sbjct: 431 LQLSLCLFLAHLLFLV--AIDQT-GHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTAR 487
Query: 685 RIILVFHHMAQHLMMAVGFCLGYGCPLIISVITIAVTQPSNTYKRKDVCWLNWSNGSKPL 744
+ +V + M + F +GYG P + + I+ + Y CWL G +
Sbjct: 488 NLTVVNYSSINRFMKKLMFPVGYGVPAV--TVAISAASRPHLYGTPSRCWLQPEKGF--I 543
Query: 745 LAFVVPALAIVAVNFVVVLLVLTKLWRPTVGERLSR-DDKATIIRVGKSLLILTP----L 799
F+ P AI +VN V L L LW + RLS + + + +R + L +
Sbjct: 544 WGFLGPVCAIFSVNLV---LFLVTLW--ILKNRLSSLNSEVSTLRNTRMLAFKATAQLFI 598
Query: 800 LGLTWGFGIGTIVDSQNLAWHVIFALLNAFQGFFILCFGILLDSKLRQLLFNKLSALSSW 859
LG TW GI + + + + +F ++N+ QG FI LL ++R+ +
Sbjct: 599 LGCTWCLGILQVGPAARVMAY-LFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKL 657
Query: 860 KQTEKQNSSDLSAKPKFSKP 879
K + ++ SAK SKP
Sbjct: 658 KTESEMHTLSSSAKADTSKP 677
>gi|23397685 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform c [Homo sapiens]
Length = 730
Score = 123 bits (308), Expect = 9e-28
Identities = 104/380 (27%), Positives = 169/380 (44%), Gaps = 30/380 (7%)
Query: 511 QNYSINEVFLFFSKIESNLSQPHCVFWDFSHL---QWNDAGCHLVNETQDIVTCQCTHLT 567
QN S F F + + CVFW+ W GC + C+CTHL+
Sbjct: 366 QNLSSPVTFTFSHRSVIPRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLS 425
Query: 568 SFSILMSPFVPSTIFPVVKWITYVGLGISIGSLILCLIIEALFWKQIKKSQTSHTRRICM 627
SF++LM+ + PV+ ITY+GL +S +LCL++ AL + K Q + T
Sbjct: 426 SFAVLMAHYDVQEEDPVLTVITYMGLSVS----LLCLLLAALTFLLCKAIQNTSTS--LH 479
Query: 628 VNIALSLLIADVWFIVGATVDTTVNPSGVCTAAVFFTHFFYLSLFFWMLMLGI---LLAY 684
+ ++L L +A + F+V +D T +C+ H+ YL+ WML+ + L A
Sbjct: 480 LQLSLCLFLAHLLFLV--AIDQT-GHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTAR 536
Query: 685 RIILVFHHMAQHLMMAVGFCLGYGCPLIISVITIAVTQPSNTYKRKDVCWLNWSNGSKPL 744
+ +V + M + F +GYG P + + I+ + Y CWL G +
Sbjct: 537 NLTVVNYSSINRFMKKLMFPVGYGVPAV--TVAISAASRPHLYGTPSRCWLQPEKGF--I 592
Query: 745 LAFVVPALAIVAVNFVVVLLVLTKLWRPTVGERLSR-DDKATIIRVGKSLLILTP----L 799
F+ P AI +VN V L L LW + RLS + + + +R + L +
Sbjct: 593 WGFLGPVCAIFSVNLV---LFLVTLW--ILKNRLSSLNSEVSTLRNTRMLAFKATAQLFI 647
Query: 800 LGLTWGFGIGTIVDSQNLAWHVIFALLNAFQGFFILCFGILLDSKLRQLLFNKLSALSSW 859
LG TW GI + + + + +F ++N+ QG FI LL ++R+ +
Sbjct: 648 LGCTWCLGILQVGPAARVMAY-LFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKL 706
Query: 860 KQTEKQNSSDLSAKPKFSKP 879
K + ++ SAK SKP
Sbjct: 707 KTESEMHTLSSSAKADTSKP 726
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,090,031
Number of Sequences: 37866
Number of extensions: 1350569
Number of successful extensions: 3528
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 50
Number of HSP's successfully gapped in prelim test: 52
Number of HSP's that attempted gapping in prelim test: 3249
Number of HSP's gapped (non-prelim): 135
length of query: 910
length of database: 18,247,518
effective HSP length: 111
effective length of query: 799
effective length of database: 14,044,392
effective search space: 11221469208
effective search space used: 11221469208
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.