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Search of human proteins with 61743916
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|61743916 carboxypeptidase A4 preproprotein [Homo sapiens]
(421 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|61743916 carboxypeptidase A4 preproprotein [Homo sapiens] 860 0.0
gi|217416390 carboxypeptidase A2 (pancreatic) precursor [Homo sa... 546 e-155
gi|4502997 carboxypeptidase A1 precursor [Homo sapiens] 489 e-138
gi|188536053 carboxypeptidase A5 isoform 1 [Homo sapiens] 449 e-126
gi|188536051 carboxypeptidase A5 isoform 1 [Homo sapiens] 449 e-126
gi|188536055 carboxypeptidase A5 isoform 2 [Homo sapiens] 338 7e-93
gi|54607080 pancreatic carboxypeptidase B1 preproprotein [Homo s... 332 3e-91
gi|188536067 carboxypeptidase A6 isoform 1 precursor [Homo sapiens] 309 3e-84
gi|221316749 carboxypeptidase A3 precursor [Homo sapiens] 300 2e-81
gi|126273569 plasma carboxypeptidase B2 isoform a preproprotein ... 258 9e-69
gi|27436871 carboxypeptidase O [Homo sapiens] 253 3e-67
gi|126273559 plasma carboxypeptidase B2 isoform b [Homo sapiens] 177 2e-44
gi|188536069 carboxypeptidase A6 isoform 2 [Homo sapiens] 108 9e-24
gi|22202611 carboxypeptidase D precursor [Homo sapiens] 74 3e-13
gi|62388879 carboxypeptidase Z isoform 3 [Homo sapiens] 60 4e-09
gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens] 60 4e-09
gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens] 60 4e-09
gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo... 59 1e-08
gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens] 58 1e-08
gi|4503011 carboxypeptidase N, polypeptide 1 precursor [Homo sap... 57 2e-08
gi|4503009 carboxypeptidase E preproprotein [Homo sapiens] 49 1e-05
gi|53832021 carboxypeptidase M precursor [Homo sapiens] 45 1e-04
gi|38327526 carboxypeptidase M precursor [Homo sapiens] 45 1e-04
gi|6631081 carboxypeptidase M precursor [Homo sapiens] 45 1e-04
gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo sap... 44 4e-04
gi|157364974 sucrase-isomaltase [Homo sapiens] 32 0.83
gi|170763513 ATP/GTP binding protein 1 [Homo sapiens] 32 1.1
gi|71061468 centromere protein E [Homo sapiens] 31 2.4
gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo s... 31 2.4
gi|113204604 aristaless-like homeobox 3 [Homo sapiens] 30 5.4
>gi|61743916 carboxypeptidase A4 preproprotein [Homo sapiens]
Length = 421
Score = 860 bits (2223), Expect = 0.0
Identities = 421/421 (100%), Positives = 421/421 (100%)
Query: 1 MRWILFIGALIGSSICGQEKFFGDQVLRINVRNGDEISKLSQLVNSNNLKLNFWKSPSSF 60
MRWILFIGALIGSSICGQEKFFGDQVLRINVRNGDEISKLSQLVNSNNLKLNFWKSPSSF
Sbjct: 1 MRWILFIGALIGSSICGQEKFFGDQVLRINVRNGDEISKLSQLVNSNNLKLNFWKSPSSF 60
Query: 61 NRPVDVLVPSVSLQAFKSFLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQERSSNNFNY 120
NRPVDVLVPSVSLQAFKSFLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQERSSNNFNY
Sbjct: 61 NRPVDVLVPSVSLQAFKSFLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQERSSNNFNY 120
Query: 121 GAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNAGI 180
GAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNAGI
Sbjct: 121 GAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNAGI 180
Query: 181 HSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRK 240
HSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRK
Sbjct: 181 HSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRK 240
Query: 241 TRSRNPGSSCIGADPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQKHGN 300
TRSRNPGSSCIGADPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQKHGN
Sbjct: 241 TRSRNPGSSCIGADPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQKHGN 300
Query: 301 FKGFIDLHSYSQLLMYPYGYSVKKAPDAEELDKVARLAAKALASVSGTEYQVGPTCTTVY 360
FKGFIDLHSYSQLLMYPYGYSVKKAPDAEELDKVARLAAKALASVSGTEYQVGPTCTTVY
Sbjct: 301 FKGFIDLHSYSQLLMYPYGYSVKKAPDAEELDKVARLAAKALASVSGTEYQVGPTCTTVY 360
Query: 361 PASGSSIDWAYDNGIKFAFTFELRDTGTYGFLLPANQIIPTAEETWLGLKTIMEHVRDNL 420
PASGSSIDWAYDNGIKFAFTFELRDTGTYGFLLPANQIIPTAEETWLGLKTIMEHVRDNL
Sbjct: 361 PASGSSIDWAYDNGIKFAFTFELRDTGTYGFLLPANQIIPTAEETWLGLKTIMEHVRDNL 420
Query: 421 Y 421
Y
Sbjct: 421 Y 421
>gi|217416390 carboxypeptidase A2 (pancreatic) precursor [Homo
sapiens]
Length = 419
Score = 546 bits (1406), Expect = e-155
Identities = 266/421 (63%), Positives = 324/421 (76%), Gaps = 4/421 (0%)
Query: 1 MRWILFIGALIGSSICGQEKFFGDQVLRINVRNGDEISKLSQLVNSNNLKLNFWKSPSSF 60
MR ILF GAL G C E F GDQVL I N ++I L QL +L+L+FWKSP++
Sbjct: 3 MRLILFFGALFGHIYC-LETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTP 61
Query: 61 NRPVDVLVPSVSLQAFKSFLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQERSSNNFNY 120
V VP V++QA K FL SQG+ Y++ IED+Q LLD E++EM N +ERS N FN+
Sbjct: 62 GETAHVRVPFVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGN-FNF 120
Query: 121 GAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNAGI 180
GAYH+LE I EMDN+ A+ P L +V IG SFENRPM VLKFSTG +PA+WL+AGI
Sbjct: 121 GAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGD--KPAIWLDAGI 178
Query: 181 HSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRK 240
H+REW++QATA+WTA KIVSDY +DP+ITSIL+ +DIFLLPV NPDGYV++QT+NR+WRK
Sbjct: 179 HAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRK 238
Query: 241 TRSRNPGSSCIGADPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQKHGN 300
TRS+ GS C+G DPNRNW+A F G GAS NPCS+ YHGP ANSEVEVKS+VDFI+ HG
Sbjct: 239 TRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGK 298
Query: 301 FKGFIDLHSYSQLLMYPYGYSVKKAPDAEELDKVARLAAKALASVSGTEYQVGPTCTTVY 360
K FI LHSYSQLLM+PYGY K D +EL +VA+ AA++L S+ GT+Y+VGP C+ +Y
Sbjct: 299 VKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIY 358
Query: 361 PASGSSIDWAYDNGIKFAFTFELRDTGTYGFLLPANQIIPTAEETWLGLKTIMEHVRDNL 420
ASG SIDW+YD GIK++F FELRDTG YGFLLPA QI+PTAEETWLGLK IMEHVRD+
Sbjct: 359 QASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHP 418
Query: 421 Y 421
Y
Sbjct: 419 Y 419
>gi|4502997 carboxypeptidase A1 precursor [Homo sapiens]
Length = 419
Score = 489 bits (1258), Expect = e-138
Identities = 229/421 (54%), Positives = 307/421 (72%), Gaps = 2/421 (0%)
Query: 1 MRWILFIGALIGSSICGQEKFFGDQVLRINVRNGDEISKLSQLVNSNNLKLNFWKSPSSF 60
MR +L + L+G+ + G+E F G QVLRI+V + ++ K+ +L + +L+L+FW+ P+
Sbjct: 1 MRGLLVLSVLLGA-VFGKEDFVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPAHP 59
Query: 61 NRPVDVLVPSVSLQAFKSFLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQERSSNNFNY 120
P+DV VP S+QA K FL S G+ Y IED+Q+LLD E ++M + RS++ FNY
Sbjct: 60 GSPIDVRVPFPSIQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNY 119
Query: 121 GAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNAGI 180
YH+LE IY +D + A+ P L +++IG+++E RP+YVLKFSTG G +RPA+W++ GI
Sbjct: 120 ATYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTG-GSKRPAIWIDTGI 178
Query: 181 HSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRK 240
HSREW++QA+ +W A+KI DY +D A T+IL+ +DIFL V NPDG+ +T + NR+WRK
Sbjct: 179 HSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRK 238
Query: 241 TRSRNPGSSCIGADPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQKHGN 300
TRS GS CIG DPNRNW+A F GAS NPCSE YHG ANSEVEVKS+VDF++ HGN
Sbjct: 239 TRSHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGN 298
Query: 301 FKGFIDLHSYSQLLMYPYGYSVKKAPDAEELDKVARLAAKALASVSGTEYQVGPTCTTVY 360
K FI +HSYSQLLMYPYGY + PD +ELD++++ A ALAS+ GT++ G +Y
Sbjct: 299 IKAFISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNYGSIIKAIY 358
Query: 361 PASGSSIDWAYDNGIKFAFTFELRDTGTYGFLLPANQIIPTAEETWLGLKTIMEHVRDNL 420
ASGS+IDW Y GIK++FTFELRDTG YGFLLPA+QIIPTA+ETWL L TIMEH ++
Sbjct: 359 QASGSTIDWTYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTLNHP 418
Query: 421 Y 421
Y
Sbjct: 419 Y 419
>gi|188536053 carboxypeptidase A5 isoform 1 [Homo sapiens]
Length = 436
Score = 449 bits (1156), Expect = e-126
Identities = 216/420 (51%), Positives = 289/420 (68%), Gaps = 1/420 (0%)
Query: 2 RWILFIGALIGSSICGQEKFFGDQVLRINVRNGDEISKLSQLVNSNNLKLNFWKSPSSFN 61
R L + + I ++ GQ F GDQVLR+ ++ ++S L L K++FW+ P+ +
Sbjct: 18 RRTLLVFSFILAAALGQMNFTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPARPS 77
Query: 62 RPVDVLVPSVSLQAFKSFLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQERSSNNFNYG 121
PVD+ VP L+ K++L S GL Y++ I+D+Q LLD E M + ERS+N+F+Y
Sbjct: 78 LPVDMRVPFSELKDIKAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSYS 137
Query: 122 AYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNAGIH 181
+YH+LE IY +DN + D+ +++IG+SFEN+ + VLKFSTG G R PA+W++ GIH
Sbjct: 138 SYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTG-GSRHPAIWIDTGIH 196
Query: 182 SREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRKT 241
SREWI+ AT IWTA KIVSDY +D +T IL MDIF+ V NPDG+ +T + NRLWRK
Sbjct: 197 SREWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKN 256
Query: 242 RSRNPGSSCIGADPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQKHGNF 301
+S PG CIG D NRNW + F G G++ NPCSE YHGP SE EV ++V+FI HGNF
Sbjct: 257 KSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHGNF 316
Query: 302 KGFIDLHSYSQLLMYPYGYSVKKAPDAEELDKVARLAAKALASVSGTEYQVGPTCTTVYP 361
K I +HSYSQ+LMYPYG ++ + EL +A+ A +AL V G EY G TT+Y
Sbjct: 317 KALISIHSYSQMLMYPYGRLLEPVSNQRELYDLAKDAVEALYKVHGIEYIFGSISTTLYV 376
Query: 362 ASGSSIDWAYDNGIKFAFTFELRDTGTYGFLLPANQIIPTAEETWLGLKTIMEHVRDNLY 421
ASG ++DWAYD+GIK+AF+FELRDTG YGFLLPA QIIPTA+ETW+ L+TIMEH ++ Y
Sbjct: 377 ASGITVDWAYDSGIKYAFSFELRDTGQYGFLLPATQIIPTAQETWMALRTIMEHTLNHPY 436
>gi|188536051 carboxypeptidase A5 isoform 1 [Homo sapiens]
Length = 436
Score = 449 bits (1156), Expect = e-126
Identities = 216/420 (51%), Positives = 289/420 (68%), Gaps = 1/420 (0%)
Query: 2 RWILFIGALIGSSICGQEKFFGDQVLRINVRNGDEISKLSQLVNSNNLKLNFWKSPSSFN 61
R L + + I ++ GQ F GDQVLR+ ++ ++S L L K++FW+ P+ +
Sbjct: 18 RRTLLVFSFILAAALGQMNFTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPARPS 77
Query: 62 RPVDVLVPSVSLQAFKSFLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQERSSNNFNYG 121
PVD+ VP L+ K++L S GL Y++ I+D+Q LLD E M + ERS+N+F+Y
Sbjct: 78 LPVDMRVPFSELKDIKAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSYS 137
Query: 122 AYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNAGIH 181
+YH+LE IY +DN + D+ +++IG+SFEN+ + VLKFSTG G R PA+W++ GIH
Sbjct: 138 SYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTG-GSRHPAIWIDTGIH 196
Query: 182 SREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRKT 241
SREWI+ AT IWTA KIVSDY +D +T IL MDIF+ V NPDG+ +T + NRLWRK
Sbjct: 197 SREWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKN 256
Query: 242 RSRNPGSSCIGADPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQKHGNF 301
+S PG CIG D NRNW + F G G++ NPCSE YHGP SE EV ++V+FI HGNF
Sbjct: 257 KSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHGNF 316
Query: 302 KGFIDLHSYSQLLMYPYGYSVKKAPDAEELDKVARLAAKALASVSGTEYQVGPTCTTVYP 361
K I +HSYSQ+LMYPYG ++ + EL +A+ A +AL V G EY G TT+Y
Sbjct: 317 KALISIHSYSQMLMYPYGRLLEPVSNQRELYDLAKDAVEALYKVHGIEYIFGSISTTLYV 376
Query: 362 ASGSSIDWAYDNGIKFAFTFELRDTGTYGFLLPANQIIPTAEETWLGLKTIMEHVRDNLY 421
ASG ++DWAYD+GIK+AF+FELRDTG YGFLLPA QIIPTA+ETW+ L+TIMEH ++ Y
Sbjct: 377 ASGITVDWAYDSGIKYAFSFELRDTGQYGFLLPATQIIPTAQETWMALRTIMEHTLNHPY 436
>gi|188536055 carboxypeptidase A5 isoform 2 [Homo sapiens]
Length = 403
Score = 338 bits (866), Expect = 7e-93
Identities = 161/330 (48%), Positives = 220/330 (66%), Gaps = 1/330 (0%)
Query: 2 RWILFIGALIGSSICGQEKFFGDQVLRINVRNGDEISKLSQLVNSNNLKLNFWKSPSSFN 61
R L + + I ++ GQ F GDQVLR+ ++ ++S L L K++FW+ P+ +
Sbjct: 18 RRTLLVFSFILAAALGQMNFTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPARPS 77
Query: 62 RPVDVLVPSVSLQAFKSFLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQERSSNNFNYG 121
PVD+ VP L+ K++L S GL Y++ I+D+Q LLD E M + ERS+N+F+Y
Sbjct: 78 LPVDMRVPFSELKDIKAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSYS 137
Query: 122 AYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNAGIH 181
+YH+LE IY +DN + D+ +++IG+SFEN+ + VLKFSTG G R PA+W++ GIH
Sbjct: 138 SYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTG-GSRHPAIWIDTGIH 196
Query: 182 SREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRKT 241
SREWI+ AT IWTA KIVSDY +D +T IL MDIF+ V NPDG+ +T + NRLWRK
Sbjct: 197 SREWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKN 256
Query: 242 RSRNPGSSCIGADPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQKHGNF 301
+S PG CIG D NRNW + F G G++ NPCSE YHGP SE EV ++V+FI HGNF
Sbjct: 257 KSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHGNF 316
Query: 302 KGFIDLHSYSQLLMYPYGYSVKKAPDAEEL 331
K I +HSYSQ+LMYPYG ++ + EL
Sbjct: 317 KALISIHSYSQMLMYPYGRLLEPVSNQREL 346
>gi|54607080 pancreatic carboxypeptidase B1 preproprotein [Homo
sapiens]
Length = 417
Score = 332 bits (852), Expect = 3e-91
Identities = 173/423 (40%), Positives = 260/423 (61%), Gaps = 15/423 (3%)
Query: 4 ILFIGALIGSSICGQEKFFGDQVLRINVRNGDEISKLSQLVNSNNLKLNFWKSPSSF--- 60
++ + + S+ G E F G++V R+NV + + I+ + +L ++ +++FWK S
Sbjct: 5 LVLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTT--QIDFWKPDSVTQIK 62
Query: 61 -NRPVDVLVPSVSLQAFKSFLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQERSSNNFN 119
+ VD V + ++ L+ L+Y V I +L+ +++ + D G +
Sbjct: 63 PHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRVRATGH-------S 115
Query: 120 YGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNAG 179
Y Y+ E I +A + P L R IG +FE R +Y+LK G +PA++++ G
Sbjct: 116 YEKYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKA-GQNKPAIFMDCG 174
Query: 180 IHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWR 239
H+REWIS A W R+ V Y R+ +T +L+K+D ++LPV N DGY+YT T++R WR
Sbjct: 175 FHAREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWR 234
Query: 240 KTRSRNPGSSCIGADPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQ-KH 298
KTRS + GSSCIG DPNRN++A + GAS NPC E Y GP A SE E K++ DFI+ K
Sbjct: 235 KTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKL 294
Query: 299 GNFKGFIDLHSYSQLLMYPYGYSVKKAPDAEELDKVARLAAKALASVSGTEYQVGPTCTT 358
+ K ++ +HSYSQ+++YPY Y+ K + EL+ +A+ K LAS+ GT+Y GP TT
Sbjct: 295 SSIKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATT 354
Query: 359 VYPASGSSIDWAYDNGIKFAFTFELRDTGTYGFLLPANQIIPTAEETWLGLKTIMEHVRD 418
+YPA+G S DWAYD GI+++FTFELRDTG YGFLLP +QI T EET+L +K + +V +
Sbjct: 355 IYPAAGGSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYVLE 414
Query: 419 NLY 421
+LY
Sbjct: 415 HLY 417
>gi|188536067 carboxypeptidase A6 isoform 1 precursor [Homo sapiens]
Length = 437
Score = 309 bits (792), Expect = 3e-84
Identities = 163/410 (39%), Positives = 235/410 (57%), Gaps = 10/410 (2%)
Query: 12 GSSICGQEKFFGDQVLRINVRNGDEISKLSQLVNSNNLKLNFWKSPS----SFNRPVDVL 67
G S ++ GD+V+R + +E L ++ S LK++ W+ S S DV
Sbjct: 28 GHSHLYNNRYAGDKVIRFIPKTEEEAYALKKI--SYQLKVDLWQPSSISYVSEGTVTDVH 85
Query: 68 VPSVSLQAFKSFLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQERSSNNFNYGAYHSLE 127
+P +A +FL+ ++Y V IEDLQ L E H + RS + +NY YHSLE
Sbjct: 86 IPQNGSRALLAFLQEANIQYKVLIEDLQKTL--EKGSSLHTQRNRRSLSGYNYEVYHSLE 143
Query: 128 AIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNAGIHSREWIS 187
I + M ++ L IG S+E R +++LK ++R AVW++ GIH+REWI
Sbjct: 144 EIQNWMHHLNKTHSGLIHMFSIGRSYEGRSLFILKLGRRSRLKR-AVWIDCGIHAREWIG 202
Query: 188 QATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRKTRSRNPG 247
A W ++ + Y+ DPA+ +L + +++PV N DGY ++ T +R WRKTRSRN
Sbjct: 203 PAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSR 262
Query: 248 SSCIGADPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQKH-GNFKGFID 306
C G D NRNW + +GAS +PC + Y GP SE EVK+V +F++KH + + ++
Sbjct: 263 FRCRGVDANRNWKVKWCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHRKHIRAYLS 322
Query: 307 LHSYSQLLMYPYGYSVKKAPDAEELDKVARLAAKALASVSGTEYQVGPTCTTVYPASGSS 366
H+Y+Q+L+YPY Y P+ ++ A A AL SV G Y+ GP TT+Y +SGSS
Sbjct: 323 FHAYAQMLLYPYSYKYATIPNFRCVESAAYKAVNALQSVYGVRYRYGPASTTLYVSSGSS 382
Query: 367 IDWAYDNGIKFAFTFELRDTGTYGFLLPANQIIPTAEETWLGLKTIMEHV 416
+DWAY NGI +AF FELRDTG +GFLLP I PT ET L +K I H+
Sbjct: 383 MDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTETMLAVKNITMHL 432
>gi|221316749 carboxypeptidase A3 precursor [Homo sapiens]
Length = 417
Score = 300 bits (767), Expect = 2e-81
Identities = 160/421 (38%), Positives = 247/421 (58%), Gaps = 14/421 (3%)
Query: 1 MRWILFIGALIGSSICGQEKFFGDQVLRINVRNGDEISKLSQLVNSNNLKLNFWKSPSSF 60
MR IL +G + + +F ++V R+ ++ + + L +N +L+FW ++
Sbjct: 1 MRLILPVGLIATTLAIAPVRFDREKVFRVKPQDEKQADIIKDLAKTN--ELDFWYPGATH 58
Query: 61 ----NRPVDVLVPSVSLQAFKSFLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQERSSN 116
N VD V QA +S L + Y + I DLQ ++ + D + G+
Sbjct: 59 HVAANMMVDFRVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVKEDIPGRH---- 114
Query: 117 NFNYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWL 176
+Y Y++ E I + + +P++ R+KIG + E+ P+YVLK K RR A++
Sbjct: 115 --SYAKYNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGE-KNERRKAIFT 171
Query: 177 NAGIHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNR 236
+ GIH+REW+S A W + Y R+ +T +L++M+ ++LPV N DGY+++ T+NR
Sbjct: 172 DCGIHAREWVSPAFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNR 231
Query: 237 LWRKTRSRNPGSSCIGADPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQ 296
+WRK RS+N S CIG D NRN+NAS+ +++PC++ Y G SE E K+V +FI+
Sbjct: 232 MWRKNRSKNQNSKCIGTDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIR 291
Query: 297 KHGN-FKGFIDLHSYSQLLMYPYGYSVKKAPDAEELDKVARLAAKALASVSGTEYQVGPT 355
H N K +I HSYSQ+L++PYGY+ K P+ E+L KVA++ L++ T Y GP
Sbjct: 292 SHLNEIKVYITFHSYSQMLLFPYGYTSKLPPNHEDLAKVAKIGTDVLSTRYETRYIYGPI 351
Query: 356 CTTVYPASGSSIDWAYDNGIKFAFTFELRDTGTYGFLLPANQIIPTAEETWLGLKTIMEH 415
+T+YP SGSS+DWAYD GIK F FELRD G +GFLLP ++I PT ET L +K I ++
Sbjct: 352 ESTIYPISGSSLDWAYDLGIKHTFAFELRDKGKFGFLLPESRIKPTCRETMLAVKFIAKY 411
Query: 416 V 416
+
Sbjct: 412 I 412
>gi|126273569 plasma carboxypeptidase B2 isoform a preproprotein
[Homo sapiens]
Length = 423
Score = 258 bits (658), Expect = 9e-69
Identities = 151/407 (37%), Positives = 224/407 (55%), Gaps = 13/407 (3%)
Query: 21 FFGDQVLRINVRNGDEISKLSQLVNSNNLKLNFWKSPSSF----NRPVDVLVPSVSLQAF 76
F QVL R ++ L L + + L W+ ++ + V V + +
Sbjct: 23 FQSGQVLAALPRTSRQVQVLQNLTTTYEIVL--WQPVTADLIVKKKQVHFFVNASDVDNV 80
Query: 77 KSFLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQERSSNNFNYGAYHSLEAIYHEMDNI 136
K+ L G+ +V + D++ L+ + + ++ R+S ++ Y YHSL IY ++ I
Sbjct: 81 KAHLNVSGIPCSVLLADVEDLIQQQ---ISNDTVSPRASASY-YEQYHSLNEIYSWIEFI 136
Query: 137 AADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNAGIHSREWISQATAIWTAR 196
PD+ ++ IG SFE P+YVLK S + + A+W++ GIH+REWIS A +W
Sbjct: 137 TERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIG 196
Query: 197 KIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRKTRSRNPGSSCIGADPN 256
I Y T++L +D +++PV N DGY Y+ +NR+WRK RS + CIG D N
Sbjct: 197 HITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLN 256
Query: 257 RNW-NASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQKHGN-FKGFIDLHSYSQLL 314
RN+ + + +GAS + CSE Y G + SE EVK+V F++++ N K +I +HSYSQ +
Sbjct: 257 RNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHI 316
Query: 315 MYPYGYSVKKAPDAEELDKVARLAAKALASVS-GTEYQVGPTCTTVYPASGSSIDWAYDN 373
++PY Y+ K+ D EEL VA A +A+ S T Y G T+Y A G DW YD
Sbjct: 317 VFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSETLYLAPGGGDDWIYDL 376
Query: 374 GIKFAFTFELRDTGTYGFLLPANQIIPTAEETWLGLKTIMEHVRDNL 420
GIK++FT ELRDTGTYGFLLP I PT E + + I HV N+
Sbjct: 377 GIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRNV 423
>gi|27436871 carboxypeptidase O [Homo sapiens]
Length = 374
Score = 253 bits (645), Expect = 3e-67
Identities = 125/304 (41%), Positives = 190/304 (62%), Gaps = 1/304 (0%)
Query: 114 SSNNFNYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPA 173
S ++Y YH + IY M I+ + ++ + +G ++E PMY LK S G +
Sbjct: 41 SLETYSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYLKISQPSGNPKKI 100
Query: 174 VWLNAGIHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQT 233
+W++ GIH+REWI+ A W ++I+ +++ + +I +L +D ++LPV N DGY+YT T
Sbjct: 101 IWMDCGIHAREWIAPAFCQWFVKEILQNHKDNSSIRKLLRNLDFYVLPVLNIDGYIYTWT 160
Query: 234 QNRLWRKTRSRNPGSSCIGADPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVD 293
+RLWRK+RS + +C G D NRN+NAS+ GAS N + + G SE E K+V
Sbjct: 161 TDRLWRKSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTFCGTGPVSEPETKAVAS 220
Query: 294 FIQ-KHGNFKGFIDLHSYSQLLMYPYGYSVKKAPDAEELDKVARLAAKALASVSGTEYQV 352
FI+ K + F+ +HSY QL++ PYGY+ K+ + E+ +V + AA AL + GT Y+V
Sbjct: 221 FIESKKDDILCFLTMHSYGQLILTPYGYTKNKSSNHPEMIQVGQKAANALKAKYGTNYRV 280
Query: 353 GPTCTTVYPASGSSIDWAYDNGIKFAFTFELRDTGTYGFLLPANQIIPTAEETWLGLKTI 412
G + +Y +SGSS DWA D GI F++TFELRD+GTYGF+LP QI PT EET + ++
Sbjct: 281 GSSADILYASSGSSRDWARDIGIPFSYTFELRDSGTYGFVLPEAQIQPTCEETMEAVLSV 340
Query: 413 MEHV 416
++ V
Sbjct: 341 LDDV 344
>gi|126273559 plasma carboxypeptidase B2 isoform b [Homo sapiens]
Length = 360
Score = 177 bits (448), Expect = 2e-44
Identities = 117/367 (31%), Positives = 179/367 (48%), Gaps = 50/367 (13%)
Query: 21 FFGDQVLRINVRNGDEISKLSQLVNSNNLKLNFWKSPSSF----NRPVDVLVPSVSLQAF 76
F QVL R ++ L L + + L W+ ++ + V V + +
Sbjct: 23 FQSGQVLAALPRTSRQVQVLQNLTTTYEIVL--WQPVTADLIVKKKQVHFFVNASDVDNV 80
Query: 77 KSFLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQERSSNNFNYGAYHSLEAIYHEMDNI 136
K+ L G+ +V + D++ L+ + + ++ R+S ++ Y YHSL IY ++ I
Sbjct: 81 KAHLNVSGIPCSVLLADVEDLIQQQ---ISNDTVSPRASASY-YEQYHSLNEIYSWIEFI 136
Query: 137 AADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNAGIHSREWISQATAIWTAR 196
PD+ ++ IG SFE P+YVLK S + + A+W++ GIH+REWIS A +W
Sbjct: 137 TERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIG 196
Query: 197 KIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRKTRSRNPGSSCIGADPN 256
NR+WRK RS + CIG D N
Sbjct: 197 -------------------------------------HNRMWRKNRSFYANNHCIGTDLN 219
Query: 257 RNWNAS-FAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQKHGN-FKGFIDLHSYSQLL 314
RN+ + + +GAS + CSE Y G + SE EVK+V F++++ N K +I +HSYSQ +
Sbjct: 220 RNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHI 279
Query: 315 MYPYGYSVKKAPDAEELDKVARLAAKALASVS-GTEYQVGPTCTTVYPASGSSIDWAYDN 373
++PY Y+ K+ D EEL VA A +A+ S T Y G T+Y A G DW YD
Sbjct: 280 VFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSETLYLAPGGGDDWIYDL 339
Query: 374 GIKFAFT 380
GIK++ T
Sbjct: 340 GIKYSVT 346
>gi|188536069 carboxypeptidase A6 isoform 2 [Homo sapiens]
Length = 193
Score = 108 bits (270), Expect = 9e-24
Identities = 49/121 (40%), Positives = 72/121 (59%), Gaps = 1/121 (0%)
Query: 143 LARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNAGIHSREWISQATAIWTARKIVSDY 202
L IG S+E R +++LK ++R AVW++ GIH+REWI A W ++ + Y
Sbjct: 11 LIHMFSIGRSYEGRSLFILKLGRRSRLKR-AVWIDCGIHAREWIGPAFCQWFVKEALLTY 69
Query: 203 QRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRKTRSRNPGSSCIGADPNRNWNAS 262
+ DPA+ +L + +++PV N DGY ++ T +R WRKTRSRN C G D NRNW
Sbjct: 70 KSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWKVK 129
Query: 263 F 263
+
Sbjct: 130 W 130
Score = 72.4 bits (176), Expect = 7e-13
Identities = 34/55 (61%), Positives = 40/55 (72%)
Query: 362 ASGSSIDWAYDNGIKFAFTFELRDTGTYGFLLPANQIIPTAEETWLGLKTIMEHV 416
+SGSS+DWAY NGI +AF FELRDTG +GFLLP I PT ET L +K I H+
Sbjct: 134 SSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTETMLAVKNITMHL 188
>gi|22202611 carboxypeptidase D precursor [Homo sapiens]
Length = 1380
Score = 73.6 bits (179), Expect = 3e-13
Identities = 73/270 (27%), Positives = 116/270 (42%), Gaps = 54/270 (20%)
Query: 110 GQERSSNNFNYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKG- 168
G E + F+ YH E + AA P LAR IG S E RP++VL+ + G G
Sbjct: 47 GAEAAEGQFDR-YYHEEELESALREAAAAGLPGLARLFSIGRSVEGRPLWVLRLTAGLGS 105
Query: 169 ---------------------VRRPAVWLNAGIHSREWISQATAIWTARKIVSDYQR-DP 206
RP V L +H E +S+ I+ AR++ + Y+R DP
Sbjct: 106 LIPEGDAGPDAAGPDAAGPLLPGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDP 165
Query: 207 AITSILEKMDIFLLPVANPDGYVYTQTQNRLWRKTRSRNPG------SSCIGADPN--RN 258
+ +L D++LLP NPDG+ + R + G S G D + R+
Sbjct: 166 RLVRLLNTTDVYLLPSLNPDGF----------ERAREGDCGFGDGGPSGASGRDNSRGRD 215
Query: 259 WNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQKHGNFKGFIDLHSYSQLLMYPY 318
N SF + ++ P P + EV++++++I+++ F +LH S + YP+
Sbjct: 216 LNRSFPDQFSTGEP-------PALDEVPEVRALIEWIRRN-KFVLSGNLHGGSVVASYPF 267
Query: 319 GYSVKKAP----DAEELDKVARLAAKALAS 344
S + D+V + AKA AS
Sbjct: 268 DDSPEHKATGIYSKTSDDEVFKYLAKAYAS 297
Score = 63.2 bits (152), Expect = 4e-10
Identities = 55/255 (21%), Positives = 102/255 (40%), Gaps = 30/255 (11%)
Query: 90 TIEDLQALLDNEDDEMQHNEGQERSSNNFNYGAY--HSLEAIYHEMDNIAADFPDLARRV 147
T ++ + L+ + E RSS+N Y HS + + + + ++P +
Sbjct: 898 TTKEFETLIKDLSAENGLESLMLRSSSNLALALYRYHSYKDLSEFLRGLVMNYPHITNLT 957
Query: 148 KIGHSFENRPMYVLKFSTGKGV---RRPAVWLNAGIHSREWISQATAIWTARKIVSDYQR 204
+G S E R ++ L+ S V P + AGIH + + A + +Y++
Sbjct: 958 NLGQSTEYRHIWSLEISNKPNVSEPEEPKIRFVAGIHGNAPVGTELLLALAEFLCLNYKK 1017
Query: 205 DPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRKTRSRNPGSSCIGADPNRNWNASFA 264
+PA+T ++++ I ++P NPDG R R C N
Sbjct: 1018 NPAVTQLVDRTRIVIVPSLNPDG--------------RERAQEKDCTSKIGQTNARGKDL 1063
Query: 265 GKGASDNPCSEVYHGPHANSEVEVKSVVDFIQKHGNFKGFIDLHSYSQLLMYPYGYSVKK 324
++N S+ E K++++ + + +F + L S L+ YPY V+
Sbjct: 1064 DTDFTNNA-----------SQPETKAIIENLIQKQDFSLSVALDGGSMLVTYPYDKPVQT 1112
Query: 325 APDAEELDKVARLAA 339
+ E L +A L A
Sbjct: 1113 VENKETLKHLASLYA 1127
Score = 57.0 bits (136), Expect = 3e-08
Identities = 62/272 (22%), Positives = 106/272 (38%), Gaps = 50/272 (18%)
Query: 137 AADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPA---VWLNAGIHSREWISQATAIW 193
A ++P++ R +G S E+R +YV++ S GV P +H E + + +
Sbjct: 517 ANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKYIGNMHGNEVVGRELLLN 576
Query: 194 TARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRKTRSRNPGSSCIGA 253
+ ++ DP +T ++ I L+P NPDGY +Q + + RN ++
Sbjct: 577 LIEYLCKNFGTDPEVTDLVHNTRIHLMPSMNPDGYEKSQEGDSI--SVIGRNNSNN---F 631
Query: 254 DPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQKHGNFKGFIDLHSYSQL 313
D NRN+ F P E +V+ +++ + F +LH S +
Sbjct: 632 DLNRNFPDQFVQITDPTQP--------------ETIAVMSWMKSY-PFVLSANLHGGSLV 676
Query: 314 LMYPYG------YSVKKAPDAEELDKVARLAAKALASVSGTEYQVGPTCTTVYP------ 361
+ YP+ + K+PD D V + A + + + +Q G C +YP
Sbjct: 677 VNYPFDDDEQGLATYSKSPD----DAVFQQIALSYSKENSQMFQ-GRPCKNMYPNEYFPH 731
Query: 362 ----------ASGSSIDWAYDNGIKFAFTFEL 383
G DW Y F T EL
Sbjct: 732 GITNGASWYNVPGGMQDWNYLQTNCFEVTIEL 763
>gi|62388879 carboxypeptidase Z isoform 3 [Homo sapiens]
Length = 515
Score = 60.1 bits (144), Expect = 4e-09
Identities = 61/241 (25%), Positives = 102/241 (42%), Gaps = 22/241 (9%)
Query: 122 AYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKG---VRRPAVWLNA 178
++HS + + A+ +AR IG SF+ R + V++FS+ G + P V L
Sbjct: 49 SHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLIG 108
Query: 179 GIHSREWISQATAIWTARKIVSDY-QRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRL 237
IH E + I+ A+ + S+Y +P I +L I LLP NPDGY +
Sbjct: 109 NIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGAG 168
Query: 238 WRKTRSRNPGSSCIGADPNRN-------WNASFAGKGASDNPCSEVYHGPHANSEVEVKS 290
+ S + D NRN + +GA + H E K+
Sbjct: 169 YNGWTSGRQNAQ--NLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPETKA 226
Query: 291 VVDFIQKHGNFKGFIDLHSYSQLLMYPYGYSVKKAPDAEEL------DKVARLAAKALAS 344
++ ++Q F LH ++ YP+ +S K P E++ +K+ +L ++A A
Sbjct: 227 IMKWMQTI-PFVLSASLHGGDLVVSYPFDFS--KHPQEEKMFSPTPDEKMFKLLSRAYAD 283
Query: 345 V 345
V
Sbjct: 284 V 284
>gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens]
Length = 641
Score = 60.1 bits (144), Expect = 4e-09
Identities = 61/241 (25%), Positives = 102/241 (42%), Gaps = 22/241 (9%)
Query: 122 AYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKG---VRRPAVWLNA 178
++HS + + A+ +AR IG SF+ R + V++FS+ G + P V L
Sbjct: 175 SHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLIG 234
Query: 179 GIHSREWISQATAIWTARKIVSDY-QRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRL 237
IH E + I+ A+ + S+Y +P I +L I LLP NPDGY +
Sbjct: 235 NIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGAG 294
Query: 238 WRKTRSRNPGSSCIGADPNRN-------WNASFAGKGASDNPCSEVYHGPHANSEVEVKS 290
+ S + D NRN + +GA + H E K+
Sbjct: 295 YNGWTSGRQNAQ--NLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPETKA 352
Query: 291 VVDFIQKHGNFKGFIDLHSYSQLLMYPYGYSVKKAPDAEEL------DKVARLAAKALAS 344
++ ++Q F LH ++ YP+ +S K P E++ +K+ +L ++A A
Sbjct: 353 IMKWMQTI-PFVLSASLHGGDLVVSYPFDFS--KHPQEEKMFSPTPDEKMFKLLSRAYAD 409
Query: 345 V 345
V
Sbjct: 410 V 410
>gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens]
Length = 652
Score = 60.1 bits (144), Expect = 4e-09
Identities = 61/241 (25%), Positives = 102/241 (42%), Gaps = 22/241 (9%)
Query: 122 AYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKG---VRRPAVWLNA 178
++HS + + A+ +AR IG SF+ R + V++FS+ G + P V L
Sbjct: 186 SHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLIG 245
Query: 179 GIHSREWISQATAIWTARKIVSDY-QRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRL 237
IH E + I+ A+ + S+Y +P I +L I LLP NPDGY +
Sbjct: 246 NIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGAG 305
Query: 238 WRKTRSRNPGSSCIGADPNRN-------WNASFAGKGASDNPCSEVYHGPHANSEVEVKS 290
+ S + D NRN + +GA + H E K+
Sbjct: 306 YNGWTSGRQNAQ--NLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPETKA 363
Query: 291 VVDFIQKHGNFKGFIDLHSYSQLLMYPYGYSVKKAPDAEEL------DKVARLAAKALAS 344
++ ++Q F LH ++ YP+ +S K P E++ +K+ +L ++A A
Sbjct: 364 IMKWMQTI-PFVLSASLHGGDLVVSYPFDFS--KHPQEEKMFSPTPDEKMFKLLSRAYAD 420
Query: 345 V 345
V
Sbjct: 421 V 421
>gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo
sapiens]
Length = 1158
Score = 58.5 bits (140), Expect = 1e-08
Identities = 59/247 (23%), Positives = 104/247 (42%), Gaps = 18/247 (7%)
Query: 123 YHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKG---VRRPAVWLNAG 179
+HS + + M + + P + R +G S +Y ++ S G + P AG
Sbjct: 564 HHSYKDMRQLMKVVNEECPTITRTYSLGKSSRGLKIYAMEISDNPGEHELGEPEFRYTAG 623
Query: 180 IHSREWISQATAIWTARKIVSDYQR-DPAITSILEKMDIFLLPVANPDGY-VYTQTQNRL 237
IH E + + + + + +Y+ +P + S+++ I L+P NPDGY V Q +
Sbjct: 624 IHGNEVLGRELLLLLMQYLCREYRDGNPRVRSLVQDTRIHLVPSLNPDGYEVAAQMGSEF 683
Query: 238 --WRKTRSRNPGSSCIGADPNRN---WNA---SFAGKGASDN--PCSEVYHGPHANSEVE 287
W G P+ N W A + +N P E Y P A E
Sbjct: 684 GNWALGLWTEEGFDIFEDFPDLNSVLWGAEERKWVPYRVPNNNLPIPERYLSPDATVSTE 743
Query: 288 VKSVVDFIQKHGNFKGFIDLHSYSQLLMYPYGYSVKKAPDAEELDKVARLAAKALASVSG 347
V++++ +++K+ G +L+ +L+ YP Y + + P E+L A AA+
Sbjct: 744 VRAIIAWMEKNPFVLG-ANLNGGERLVSYP--YDMARTPTQEQLLAAAMAAARGEDEDEV 800
Query: 348 TEYQVGP 354
+E Q P
Sbjct: 801 SEAQETP 807
>gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens]
Length = 734
Score = 58.2 bits (139), Expect = 1e-08
Identities = 55/216 (25%), Positives = 93/216 (43%), Gaps = 26/216 (12%)
Query: 123 YHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKG---VRRPAVWLNAG 179
+H+ +A+ M + P++ R IG S++ +YV++ S G + P V AG
Sbjct: 299 HHNYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYVMEMSDKPGEHELGEPEVRYVAG 358
Query: 180 IHSREWISQATAIWTARKIVSDYQR-DPAITSILEKMDIFLLPVANPDGY--VYTQTQNR 236
+H E + + + + + ++ R +P +T +L +M I LLP NPDGY Y +
Sbjct: 359 MHGNEALGRELLLLLMQFLCHEFLRGNPRVTRLLSEMRIHLLPSMNPDGYEIAYHRGSEL 418
Query: 237 L-WRKTRSRNPGSSCIGADPNRN--------WNASFAGK-----GASDNPCSEVYHGPHA 282
+ W + R N D N N W A GK P Y P+A
Sbjct: 419 VGWAEGRWNNQ-----SIDLNHNFADLNTPLWEAQDDGKVPHIVPNHHLPLPTYYTLPNA 473
Query: 283 NSEVEVKSVVDFIQKHGNFKGFIDLHSYSQLLMYPY 318
E ++V+ ++ K F +LH ++ YP+
Sbjct: 474 TVAPETRAVIKWM-KRIPFVLSANLHGGELVVSYPF 508
>gi|4503011 carboxypeptidase N, polypeptide 1 precursor [Homo
sapiens]
Length = 458
Score = 57.4 bits (137), Expect = 2e-08
Identities = 63/269 (23%), Positives = 106/269 (39%), Gaps = 47/269 (17%)
Query: 123 YHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVR---RPAVWLNAG 179
+H + + + + + P + R IG S E R +YVL+FS G+ P V
Sbjct: 25 HHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVGN 84
Query: 180 IHSREWISQATAIWTARKIVSDYQ-RDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLW 238
+H E + + + + + +++ R+ I +++ I +LP NPDGY Q
Sbjct: 85 MHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQG--- 141
Query: 239 RKTRSRNPG-----SSCIGADPNRN---------WNASFAGKG----ASDNPCSEVYHGP 280
PG ++ G D NRN +N + G DN S+V
Sbjct: 142 ----PNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPNHHLPLPDNWKSQV---- 193
Query: 281 HANSEVEVKSVVDFIQKHGNFKGFIDLHSYSQLLMYPYGYSV--------KKAPDAEELD 332
E E ++V+ ++ NF +LH + + YPY S + A D
Sbjct: 194 ----EPETRAVIRWMHSF-NFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTASTPTPDD 248
Query: 333 KVARLAAKALASVSGTEYQVGPTCTTVYP 361
K+ + AK + G +Q G C +P
Sbjct: 249 KLFQKLAKVYSYAHGWMFQ-GWNCGDYFP 276
>gi|4503009 carboxypeptidase E preproprotein [Homo sapiens]
Length = 476
Score = 48.5 bits (114), Expect = 1e-05
Identities = 35/144 (24%), Positives = 65/144 (45%), Gaps = 12/144 (8%)
Query: 123 YHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPA---VWLNAG 179
YH + + ++ ++R +G SFE R + V++ S GV P
Sbjct: 53 YHRYPELREALVSVWLQCTAISRIYTVGRSFEGRELLVIELSDNPGVHEPGEPEFKYIGN 112
Query: 180 IHSREWISQATAIWTARKIVSDYQR-DPAITSILEKMDIFLLPVANPDGYVYTQTQN--- 235
+H E + + I+ A+ + ++YQ+ + I +++ I ++P NPDG+ +Q
Sbjct: 113 MHGNEAVGRELLIFLAQYLCNEYQKGNETIVNLIHSTRIHIMPSLNPDGFEKAASQPGEL 172
Query: 236 RLWRKTRSRNPGSSCIGADPNRNW 259
+ W R S+ G D NRN+
Sbjct: 173 KDWFVGR-----SNAQGIDLNRNF 191
>gi|53832021 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 45.1 bits (105), Expect = 1e-04
Identities = 28/115 (24%), Positives = 53/115 (46%), Gaps = 6/115 (5%)
Query: 117 NFNYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVL---KFSTGKGVRRPA 173
+FNY +EA + +A ++ + IG S + R ++VL +F + P
Sbjct: 19 DFNYHRQEGMEAF---LKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPE 75
Query: 174 VWLNAGIHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGY 228
A +H E + + + +V+ +DP IT+++ I ++P NPDG+
Sbjct: 76 FKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGF 130
>gi|38327526 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 45.1 bits (105), Expect = 1e-04
Identities = 28/115 (24%), Positives = 53/115 (46%), Gaps = 6/115 (5%)
Query: 117 NFNYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVL---KFSTGKGVRRPA 173
+FNY +EA + +A ++ + IG S + R ++VL +F + P
Sbjct: 19 DFNYHRQEGMEAF---LKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPE 75
Query: 174 VWLNAGIHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGY 228
A +H E + + + +V+ +DP IT+++ I ++P NPDG+
Sbjct: 76 FKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGF 130
>gi|6631081 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 45.1 bits (105), Expect = 1e-04
Identities = 28/115 (24%), Positives = 53/115 (46%), Gaps = 6/115 (5%)
Query: 117 NFNYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVL---KFSTGKGVRRPA 173
+FNY +EA + +A ++ + IG S + R ++VL +F + P
Sbjct: 19 DFNYHRQEGMEAF---LKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPE 75
Query: 174 VWLNAGIHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGY 228
A +H E + + + +V+ +DP IT+++ I ++P NPDG+
Sbjct: 76 FKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGF 130
>gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo
sapiens]
Length = 756
Score = 43.5 bits (101), Expect = 4e-04
Identities = 31/114 (27%), Positives = 50/114 (43%), Gaps = 10/114 (8%)
Query: 119 NYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKG---VRRPAVW 175
NY L + +EM P++ R IG S + +Y ++ S G V P
Sbjct: 320 NYKEMRQLMKVVNEM------CPNITRIYNIGKSHQGLKLYAVEISDHPGEHEVGEPEFH 373
Query: 176 LNAGIHSREWISQATAIWTARKIVSDY-QRDPAITSILEKMDIFLLPVANPDGY 228
AG H E + + + + + +Y R+ I ++E+ I +LP NPDGY
Sbjct: 374 YIAGAHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIHVLPSLNPDGY 427
>gi|157364974 sucrase-isomaltase [Homo sapiens]
Length = 1827
Score = 32.3 bits (72), Expect = 0.83
Identities = 35/154 (22%), Positives = 64/154 (41%), Gaps = 29/154 (18%)
Query: 119 NYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNA 178
N+G + + ++Y IA + + F N+ ++L ST G +
Sbjct: 551 NWGKQYDVHSLYGYSMAIATE-------QAVQKVFPNKRSFILTRSTFAG---------S 594
Query: 179 GIHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPD--GYVYTQTQN- 235
G H+ W+ TA W Q + +IT +LE +F +P+ D G+V T+
Sbjct: 595 GRHAAHWLGDNTASWE--------QMEWSITGMLE-FSLFGIPLVGADICGFVAETTEEL 645
Query: 236 -RLWRKTRSRNPGSSCIGADPNRNWNASFAGKGA 268
R W + + P S +D + + +F G+ +
Sbjct: 646 CRRWMQLGAFYPFSRNHNSDGYEHQDPAFFGQNS 679
>gi|170763513 ATP/GTP binding protein 1 [Homo sapiens]
Length = 1186
Score = 32.0 bits (71), Expect = 1.1
Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 16/91 (17%)
Query: 171 RPAVWLNAGIHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVY 230
RP V+L+A +H E + T ++S+ +P S+ E ++P+ NPDG +
Sbjct: 870 RPYVFLSARVHPGETNASWVMKGTLEYLMSN---NPTAQSLRESYIFKIVPMLNPDGVI- 925
Query: 231 TQTQNRLWRKTRSRNPGSSCIGADPNRNWNA 261
+ N S G D NR W +
Sbjct: 926 ------------NGNHRCSLSGEDLNRQWQS 944
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 30.8 bits (68), Expect = 2.4
Identities = 24/114 (21%), Positives = 53/114 (46%), Gaps = 10/114 (8%)
Query: 35 DEISKLSQLVNSN---NLKLNFWKSPSSFNRPVDVL-----VPSVSLQAFK--SFLRSQG 84
D+I KL + ++S N+K++ S S P + +V+L A + +FLRS+
Sbjct: 589 DQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSEN 648
Query: 85 LEYAVTIEDLQALLDNEDDEMQHNEGQERSSNNFNYGAYHSLEAIYHEMDNIAA 138
LE +++L ++++Q + Q + L++ ++E+ + +
Sbjct: 649 LELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTS 702
>gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo
sapiens]
Length = 508
Score = 30.8 bits (68), Expect = 2.4
Identities = 18/56 (32%), Positives = 31/56 (55%)
Query: 57 PSSFNRPVDVLVPSVSLQAFKSFLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQE 112
P+S +R V +L FK FL S G + A +DL+ L + E+ +M+ ++ Q+
Sbjct: 447 PASADRTVIDYNGERTLDGFKKFLESGGQDGAGDDDDLEDLEEAEEPDMEEDDDQK 502
>gi|113204604 aristaless-like homeobox 3 [Homo sapiens]
Length = 343
Score = 29.6 bits (65), Expect = 5.4
Identities = 25/101 (24%), Positives = 35/101 (34%), Gaps = 22/101 (21%)
Query: 185 WISQATAIWTARKIVSDYQ--RDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRKTR 242
W A W R+ Q R+P + DI +LP + + Q QN LW
Sbjct: 200 WFQNRRAKWRKRERYGKIQEGRNPFTAAY----DISVLPRTDS----HPQLQNSLWASPG 251
Query: 243 SRNPGSSCIGADPNRNWNASFAGKGASDNPCSEVYHGPHAN 283
S +PG C+ +PC Y PH +
Sbjct: 252 SGSPGGPCL------------VSPEGIPSPCMSPYSHPHGS 280
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,065,077
Number of Sequences: 37866
Number of extensions: 685570
Number of successful extensions: 1606
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 1542
Number of HSP's gapped (non-prelim): 42
length of query: 421
length of database: 18,247,518
effective HSP length: 105
effective length of query: 316
effective length of database: 14,271,588
effective search space: 4509821808
effective search space used: 4509821808
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.