Search of human proteins with 13489087

Search of human proteins with 13489087

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13489087 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 1 [Homo sapiens]
         (379 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13489087 serine (or cysteine) proteinase inhibitor, clade B (...   749   0.0  
gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo s...   379   e-105
gi|38504669 serine (or cysteine) proteinase inhibitor, clade B (...   372   e-103
gi|38504673 serine (or cysteine) proteinase inhibitor, clade B (...   372   e-103
gi|41152086 serine (or cysteine) proteinase inhibitor, clade B (...   368   e-102
gi|219689110 serine (or cysteine) proteinase inhibitor, clade B ...   361   e-100
gi|4505595 serine (or cysteine) proteinase inhibitor, clade B (o...   361   e-100
gi|28076869 serine (or cysteine) proteinase inhibitor, clade B (...   352   3e-97
gi|5902072 serine (or cysteine) proteinase inhibitor, clade B (o...   351   5e-97
gi|4826902 serine (or cysteine) proteinase inhibitor, clade B (o...   343   1e-94
gi|8393956 serine (or cysteine) proteinase inhibitor, clade B (o...   338   6e-93
gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Hom...   330   1e-90
gi|167860126 serine (or cysteine) proteinase inhibitor, clade B ...   314   1e-85
gi|17998551 serine (or cysteine) proteinase inhibitor, clade B (...   314   1e-85
gi|92859634 serine (or cysteine) proteinase inhibitor, clade B (...   277   1e-74
gi|4505149 serine (or cysteine) proteinase inhibitor, clade B (o...   277   1e-74
gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo s...   259   4e-69
gi|73623033 serine (or cysteine) proteinase inhibitor, clade B (...   236   3e-62
gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member...   219   4e-57
gi|170295807 neuroserpin precursor [Homo sapiens]                     212   4e-55
gi|4826904 neuroserpin precursor [Homo sapiens]                       212   4e-55
gi|50659080 serpin peptidase inhibitor, clade A, member 3 precur...   207   1e-53
gi|73858566 heparin cofactor II precursor [Homo sapiens]              198   8e-51
gi|110225347 serine (or cysteine) proteinase inhibitor, clade A ...   194   1e-49
gi|211904156 plasminogen activator inhibitor type 1, member 2 is...   189   3e-48
gi|211904154 plasminogen activator inhibitor type 1, member 2 is...   189   3e-48
gi|211904152 plasminogen activator inhibitor type 1, member 2 is...   189   3e-48
gi|194018472 serine (or cysteine) proteinase inhibitor, clade A ...   189   3e-48
gi|24307907 plasminogen activator inhibitor type 1, member 2 iso...   188   8e-48
gi|32454741 serine (or cysteine) proteinase inhibitor, clade H, ...   182   3e-46

>gi|13489087 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 1 [Homo sapiens]
          Length = 379

 Score =  749 bits (1935), Expect = 0.0
 Identities = 379/379 (100%), Positives = 379/379 (100%)

Query: 1   MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF 60
           MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF
Sbjct: 1   MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF 60

Query: 61  NTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVD 120
           NTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVD
Sbjct: 61  NTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVD 120

Query: 121 FQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEAT 180
           FQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEAT
Sbjct: 121 FQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEAT 180

Query: 181 TNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDES 240
           TNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDES
Sbjct: 181 TNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDES 240

Query: 241 TGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSS 300
           TGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSS
Sbjct: 241 TGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSS 300

Query: 301 KADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTADHPFLF 360
           KADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTADHPFLF
Sbjct: 301 KADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTADHPFLF 360

Query: 361 FIRHNSSGSILFLGRFSSP 379
           FIRHNSSGSILFLGRFSSP
Sbjct: 361 FIRHNSSGSILFLGRFSSP 379


>gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo
           sapiens]
          Length = 376

 Score =  379 bits (972), Expect = e-105
 Identities = 194/380 (51%), Positives = 260/380 (68%), Gaps = 5/380 (1%)

Query: 1   MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF 60
           ME LS+A+  FA+ L   L ++NP+ N+F SP SISSA+AMV LG +GNTA Q+++    
Sbjct: 1   METLSNASGTFAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSL 60

Query: 61  NTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVD 120
           NT E++H  FQSL  ++NK G  Y+L+ ANRL+GEKT  FL  F  S  + Y A+L  + 
Sbjct: 61  NTEEDIHRAFQSLLTEVNKAGTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAELKELS 120

Query: 121 FQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEAT 180
           F  A+E++RK IN WV  +TEGKI ELL    +D  T+LVLVNAIYFKG W + F +  T
Sbjct: 121 FIRAAEESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYT 180

Query: 181 TNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDES 240
              PF++N+++++ V+MMYQ+  F   ++ +++ ++LELPY  +ELS+++LLPDD  + S
Sbjct: 181 REMPFKINQEEQRPVQMMYQEATFKLAHVGEVRAQLLELPYARKELSLLVLLPDDGVELS 240

Query: 241 TGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSS 300
           T    +E+ LT EKL  WTKP+ +   EV V LP+FKL+E Y + S L  LG+ D F   
Sbjct: 241 T----VEKSLTFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQG 296

Query: 301 KADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATA-GIATFCMLMPEENFTADHPFL 359
           KADLS MS  RD+ +SK VHKSFVEVNEEGTEAAAA++  +   C +     F ADHPFL
Sbjct: 297 KADLSAMSAERDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCMESGPRFCADHPFL 356

Query: 360 FFIRHNSSGSILFLGRFSSP 379
           FFIRHN + SILF GRFSSP
Sbjct: 357 FFIRHNRANSILFCGRFSSP 376


>gi|38504669 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 8 isoform a [Homo sapiens]
          Length = 374

 Score =  372 bits (956), Expect = e-103
 Identities = 197/379 (51%), Positives = 258/379 (68%), Gaps = 5/379 (1%)

Query: 1   MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF 60
           M+ L  AN  FA+ LF  L E + + N+F SP SISSA+AMVF+G +G+TAAQ+S+    
Sbjct: 1   MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60

Query: 61  NTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVD 120
               ++H  FQSL +++N+ G  Y+L+ ANRL+GEKT +FLP+F    QK Y A+L  + 
Sbjct: 61  YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS 120

Query: 121 FQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEAT 180
           F   +E+ RK IN WV  +TEGKI E+L +G VD +TKLVLVNAIYFKG W ++F ++ T
Sbjct: 121 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT 180

Query: 181 TNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDES 240
               F+ N +++KTV+MM+++ KF  GY +++  +VLELPY  EELSMVILLPDD    +
Sbjct: 181 RGMLFKTN-EEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDD----N 235

Query: 241 TGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSS 300
           T L  +E+ LT EK   WT  E L   +V V LPR KLEESY L   L RLG+ D F+ +
Sbjct: 236 TDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEA 295

Query: 301 KADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTADHPFLF 360
           KAD SGMS  +++ +SK+ HK FVEVNEEGTEAAAATA +        E  F ADHPFLF
Sbjct: 296 KADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLF 355

Query: 361 FIRHNSSGSILFLGRFSSP 379
           FIRH+ +  ILF GRFSSP
Sbjct: 356 FIRHHKTNCILFCGRFSSP 374


>gi|38504673 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 8 isoform a [Homo sapiens]
          Length = 374

 Score =  372 bits (956), Expect = e-103
 Identities = 197/379 (51%), Positives = 258/379 (68%), Gaps = 5/379 (1%)

Query: 1   MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF 60
           M+ L  AN  FA+ LF  L E + + N+F SP SISSA+AMVF+G +G+TAAQ+S+    
Sbjct: 1   MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60

Query: 61  NTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVD 120
               ++H  FQSL +++N+ G  Y+L+ ANRL+GEKT +FLP+F    QK Y A+L  + 
Sbjct: 61  YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS 120

Query: 121 FQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEAT 180
           F   +E+ RK IN WV  +TEGKI E+L +G VD +TKLVLVNAIYFKG W ++F ++ T
Sbjct: 121 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT 180

Query: 181 TNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDES 240
               F+ N +++KTV+MM+++ KF  GY +++  +VLELPY  EELSMVILLPDD    +
Sbjct: 181 RGMLFKTN-EEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDD----N 235

Query: 241 TGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSS 300
           T L  +E+ LT EK   WT  E L   +V V LPR KLEESY L   L RLG+ D F+ +
Sbjct: 236 TDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEA 295

Query: 301 KADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTADHPFLF 360
           KAD SGMS  +++ +SK+ HK FVEVNEEGTEAAAATA +        E  F ADHPFLF
Sbjct: 296 KADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLF 355

Query: 361 FIRHNSSGSILFLGRFSSP 379
           FIRH+ +  ILF GRFSSP
Sbjct: 356 FIRHHKTNCILFCGRFSSP 374


>gi|41152086 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 6 [Homo sapiens]
          Length = 376

 Score =  368 bits (944), Expect = e-102
 Identities = 195/382 (51%), Positives = 264/382 (69%), Gaps = 9/382 (2%)

Query: 1   MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF 60
           M+ L+ AN  FAL+L   L ++N + N+F SP S+S A+AMV++G +GNTAAQ+++   F
Sbjct: 1   MDVLAEANGTFALNLLKTLGKDN-SKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF 59

Query: 61  NTVE---EVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLA 117
           N      ++H  FQSL  ++NK G  Y+L++ANRL+GEK+ +FL  F  S QK Y A++ 
Sbjct: 60  NKSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEME 119

Query: 118 SVDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMK 177
            +DF  A E +RK IN WV  +TEGKI ELL+ G VD +T+LVLVNA+YF+GNW ++F K
Sbjct: 120 ELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDK 179

Query: 178 EATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIE 237
           E T    F+++K + K V+MM+++  F   YI ++  ++L LPY G+EL+M+I+LP    
Sbjct: 180 ENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLP---- 235

Query: 238 DESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLF 297
           DE+T L+ +E++LT EK  EWT+ + +D  EV VSLPRFKLEESY + S L  LG+ D F
Sbjct: 236 DETTDLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAF 295

Query: 298 NSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTADHP 357
              KAD SGMS   D+ +SK+VHKSFVEVNEEGTEAAAATA I           F ADHP
Sbjct: 296 ELGKADFSGMS-QTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHP 354

Query: 358 FLFFIRHNSSGSILFLGRFSSP 379
           FLFFI+H+ +  ILF GRFSSP
Sbjct: 355 FLFFIQHSKTNGILFCGRFSSP 376


>gi|219689110 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 2 [Homo sapiens]
          Length = 415

 Score =  361 bits (927), Expect = e-100
 Identities = 190/416 (45%), Positives = 263/416 (63%), Gaps = 38/416 (9%)

Query: 1   MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF 60
           ME L  ANT FAL+LF  L++ +P  N+F+SP+SISS MAMV++G+RG+T  Q++K   F
Sbjct: 1   MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60

Query: 61  NTV-------------------------------------EEVHSRFQSLNADINKRGAS 83
           N V                                     +++HS F+SL++ IN    +
Sbjct: 61  NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120

Query: 84  YILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVDFQHASEDARKTINQWVKGQTEGK 143
           Y+L+  N+L+GEK+ +F  E++   QK Y ++  +VDF   +E+ARK IN WVK QT+GK
Sbjct: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180

Query: 144 IPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEATTNAPFRLNKKDRKTVKMMYQKKK 203
           IP LL  G VD  T++VLVNA+YFKG WK  F K+     PFR+N   R  V+MMY ++K
Sbjct: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240

Query: 204 FAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDESTGLKKIEEQLTLEKLHEWTKPEN 263
              GYIEDLK ++LELPY G ++SM +LLPD+I D STGL+ +E ++T +KL++WT  + 
Sbjct: 241 LNIGYIEDLKAQILELPYAG-DVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299

Query: 264 LDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSSKADLSGMSGARDIFISKIVHKSF 323
           +   EV V +P+FKLEE Y L S L  +G++D FN  +A+ SGMS   D+F+S++ H++ 
Sbjct: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359

Query: 324 VEVNEEGTEAAAATAGIATFCMLMPEENFTADHPFLFFIRHNSSGSILFLGRFSSP 379
           V+VNEEGTEAAA T G+ T         F ADHPFLF I H  +  ILF GRFSSP
Sbjct: 360 VDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415


>gi|4505595 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 2 [Homo sapiens]
          Length = 415

 Score =  361 bits (927), Expect = e-100
 Identities = 190/416 (45%), Positives = 263/416 (63%), Gaps = 38/416 (9%)

Query: 1   MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF 60
           ME L  ANT FAL+LF  L++ +P  N+F+SP+SISS MAMV++G+RG+T  Q++K   F
Sbjct: 1   MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60

Query: 61  NTV-------------------------------------EEVHSRFQSLNADINKRGAS 83
           N V                                     +++HS F+SL++ IN    +
Sbjct: 61  NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120

Query: 84  YILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVDFQHASEDARKTINQWVKGQTEGK 143
           Y+L+  N+L+GEK+ +F  E++   QK Y ++  +VDF   +E+ARK IN WVK QT+GK
Sbjct: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180

Query: 144 IPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEATTNAPFRLNKKDRKTVKMMYQKKK 203
           IP LL  G VD  T++VLVNA+YFKG WK  F K+     PFR+N   R  V+MMY ++K
Sbjct: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240

Query: 204 FAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDESTGLKKIEEQLTLEKLHEWTKPEN 263
              GYIEDLK ++LELPY G ++SM +LLPD+I D STGL+ +E ++T +KL++WT  + 
Sbjct: 241 LNIGYIEDLKAQILELPYAG-DVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299

Query: 264 LDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSSKADLSGMSGARDIFISKIVHKSF 323
           +   EV V +P+FKLEE Y L S L  +G++D FN  +A+ SGMS   D+F+S++ H++ 
Sbjct: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359

Query: 324 VEVNEEGTEAAAATAGIATFCMLMPEENFTADHPFLFFIRHNSSGSILFLGRFSSP 379
           V+VNEEGTEAAA T G+ T         F ADHPFLF I H  +  ILF GRFSSP
Sbjct: 360 VDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415


>gi|28076869 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 4 [Homo sapiens]
          Length = 390

 Score =  352 bits (903), Expect = 3e-97
 Identities = 191/396 (48%), Positives = 254/396 (64%), Gaps = 23/396 (5%)

Query: 1   MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF 60
           M  LS ANT+F  DLF    ++    NIF SP SI+SA+ MV LG + NTA Q+SK  HF
Sbjct: 1   MNSLSEANTKFMFDLFQQFRKSKE-NNIFYSPISITSALGMVLLGAKDNTAQQISKVLHF 59

Query: 61  NTVEE----------------VHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEF 104
           + V E                VH +FQ L  + NK   +Y LK+AN+L+GEKTY FL E+
Sbjct: 60  DQVTENTTEKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEY 119

Query: 105 LVSTQKTYGADLASVDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNA 164
           L + +K Y   + S DF +A E++RK IN WV+ QT  KI  L   G + N T LVLVNA
Sbjct: 120 LDAIKKFYQTSVESTDFANAPEESRKKINSWVESQTNEKIKNLFPDGTIGNDTTLVLVNA 179

Query: 165 IYFKGNWKDKFMKEATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGE 224
           IYFKG W++KF KE T    F  NK   K+V+MM Q   F +  +ED++ +VLE+PY+G+
Sbjct: 180 IYFKGQWENKFKKENTKEEKFWPNKNTYKSVQMMRQYNSFNFALLEDVQAKVLEIPYKGK 239

Query: 225 ELSMVILLPDDIEDESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTL 284
           +LSM++LLP++I+    GL+K+EE+LT EKL EWT  +N+    V++ LPRFK+EESY L
Sbjct: 240 DLSMIVLLPNEID----GLQKLEEKLTAEKLMEWTSLQNMRETCVDLHLPRFKMEESYDL 295

Query: 285 NSDLARLGVQDLFNSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIAT-F 343
              L  +G+ ++FN   ADLSGM+ +  + +SK++HK+FVEV EEG EAAAATA +    
Sbjct: 296 KDTLRTMGMVNIFNGD-ADLSGMTWSHGLSVSKVLHKAFVEVTEEGVEAAAATAVVVVEL 354

Query: 344 CMLMPEENFTADHPFLFFIRHNSSGSILFLGRFSSP 379
                 E F  +HPFLFFIR N + SILF GRFSSP
Sbjct: 355 SSPSTNEEFCCNHPFLFFIRQNKTNSILFYGRFSSP 390


>gi|5902072 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 3 [Homo sapiens]
          Length = 390

 Score =  351 bits (901), Expect = 5e-97
 Identities = 191/396 (48%), Positives = 255/396 (64%), Gaps = 23/396 (5%)

Query: 1   MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF 60
           M  LS ANT+F  DLF    ++    NIF SP SI+SA+ MV LG + NTA Q+ K  HF
Sbjct: 1   MNSLSEANTKFMFDLFQQFRKSKE-NNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHF 59

Query: 61  NTVEE----------------VHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEF 104
           + V E                VH +FQ L  + NK   +Y LK+AN+L+GEKTY FL E+
Sbjct: 60  DQVTENTTGKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEY 119

Query: 105 LVSTQKTYGADLASVDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNA 164
           L + +K Y   + SVDF +A E++RK IN WV+ QT  KI  L+  G + + T LVLVNA
Sbjct: 120 LDAIKKFYQTSVESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNA 179

Query: 165 IYFKGNWKDKFMKEATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGE 224
           IYFKG W+ KF KE T    F  NK   K+++MM Q   F +  +ED++ +VLE+PY+G+
Sbjct: 180 IYFKGQWEKKFNKEDTKEEKFWPNKNTYKSIQMMRQYTSFHFASLEDVQAKVLEIPYKGK 239

Query: 225 ELSMVILLPDDIEDESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTL 284
           +LSM++LLP++I+    GL+K+EE+LT EKL EWT  +N+    V++ LPRFK+EESY L
Sbjct: 240 DLSMIVLLPNEID----GLQKLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDL 295

Query: 285 NSDLARLGVQDLFNSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIA-TF 343
              L  +G+ D+FN   ADLSGM+G+R + +S ++HK+FVEV EEG EAAAATA +    
Sbjct: 296 KDTLRTMGMVDIFNGD-ADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGS 354

Query: 344 CMLMPEENFTADHPFLFFIRHNSSGSILFLGRFSSP 379
                 E F  +HPFLFFIR N + SILF GRFSSP
Sbjct: 355 SPTSTNEEFHCNHPFLFFIRQNKTNSILFYGRFSSP 390


>gi|4826902 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 10 [Homo sapiens]
          Length = 397

 Score =  343 bits (880), Expect = 1e-94
 Identities = 178/401 (44%), Positives = 259/401 (64%), Gaps = 26/401 (6%)

Query: 1   MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF 60
           M+ L+++  +FAL+L   L+E+    NIF S +SIS+++ +V+LG +G TAAQ+++   F
Sbjct: 1   MDSLATSINQFALELSKKLAESAQGKNIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQF 60

Query: 61  N----------------------TVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTY 98
           N                        EE+HS FQ+L ++I K    Y+LK AN +YGEKTY
Sbjct: 61  NRDQGVKCDPESEKKRKMEFNLSNSEEIHSDFQTLISEILKPNDDYLLKTANAIYGEKTY 120

Query: 99  NFLPEFLVSTQKTYGADLASVDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTK 158
            F  ++L   +  +GA+   V+F  AS+  RK IN WV+ QTEGKI  LL    VD+ T+
Sbjct: 121 AFHNKYLEDMKTYFGAEPQPVNFVEASDQIRKDINSWVERQTEGKIQNLLPDDSVDSTTR 180

Query: 159 LVLVNAIYFKGNWKDKFMKEATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLE 218
           ++LVNA+YFKG W+ +F+ + TT  PFR+N+   K V+MM+ KKK    +IE  K   L+
Sbjct: 181 MILVNALYFKGIWEHQFLVQNTTEKPFRINETTSKPVQMMFMKKKLHIFHIEKPKAVGLQ 240

Query: 219 LPYQGEELSMVILLPDDIEDESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKL 278
           L Y+  +LS++ILLP+DI     GL+++E+ +T EKL+EWT  + ++  EV + LP+FKL
Sbjct: 241 LYYKSRDLSLLILLPEDI----NGLEQLEKAITYEKLNEWTSADMMELYEVQLHLPKFKL 296

Query: 279 EESYTLNSDLARLGVQDLFNSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATA 338
           E+SY L S L+ +G+ D F+ SKAD SGMS AR++F+S + HK+FVE+NE+GTEAAA + 
Sbjct: 297 EDSYDLKSTLSSMGMSDAFSQSKADFSGMSSARNLFLSNVFHKAFVEINEQGTEAAAGSG 356

Query: 339 GIATFCMLMPEENFTADHPFLFFIRHNSSGSILFLGRFSSP 379
                 + +P   F A+HPFLFFIRHN + +ILF GR  SP
Sbjct: 357 SEIDIRIRVPSIEFNANHPFLFFIRHNKTNTILFYGRLCSP 397


>gi|8393956 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 13 [Homo sapiens]
          Length = 391

 Score =  338 bits (866), Expect = 6e-93
 Identities = 180/396 (45%), Positives = 245/396 (61%), Gaps = 22/396 (5%)

Query: 1   MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFH- 59
           M+ L + +TR   DLF  L + N  GNIF SP  I +A+ MV LGTRG TA+QL + FH 
Sbjct: 1   MDSLGAVSTRLGFDLFKELKKTND-GNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHS 59

Query: 60  ----------------FNTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPE 103
                               E VH +FQ    +I+K    Y L + NRL+GEKTY FL +
Sbjct: 60  EKETKSSRIKAEEKEVIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQK 119

Query: 104 FLVSTQKTYGADLASVDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVN 163
           +L   +K Y A L  VDF +A++++RK IN WV+ +T  KI +L   G + + TKLVLVN
Sbjct: 120 YLDYVEKYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVN 179

Query: 164 AIYFKGNWKDKFMKEATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQG 223
            +YFKG W  +F KE T    F +NK   K+V+MM Q   F++ ++EDL+ ++L +PY+ 
Sbjct: 180 MVYFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKN 239

Query: 224 EELSMVILLPDDIEDESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYT 283
            +LSM +LLP+DI+    GL+KI ++++ EKL EWT P +++  +VN+ LPRF++E+ Y 
Sbjct: 240 NDLSMFVLLPNDID----GLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYD 295

Query: 284 LNSDLARLGVQDLFNSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATF 343
           L + LA +G+ D F+  KAD SGMS    ++  K +H SFV V EEGTEAAAAT    T 
Sbjct: 296 LEAVLAAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTV 355

Query: 344 CMLMPEENFTADHPFLFFIRHNSSGSILFLGRFSSP 379
                 EN   +HPFLFFIRHN S SILF GRFSSP
Sbjct: 356 TSAPGHENVHCNHPFLFFIRHNESNSILFFGRFSSP 391


>gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Homo
           sapiens]
          Length = 392

 Score =  330 bits (847), Expect = 1e-90
 Identities = 181/396 (45%), Positives = 242/396 (61%), Gaps = 21/396 (5%)

Query: 1   MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF 60
           M  LS+AN  F LD+F  L+ NN   NIF S  S+  A++MV LG RG T  QL K  HF
Sbjct: 1   MGSLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHF 60

Query: 61  N-TVEE----------------VHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPE 103
           + TV+                 +HS F    + IN+  ++  L +ANRLYG KT  F  +
Sbjct: 61  SHTVDSLKPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQ 120

Query: 104 FLVSTQKTYGADLASVDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVN 163
           +L  ++K Y A L +VDF+ ++E+ RKTIN WV+ +T GK+  L     +D  + +VLVN
Sbjct: 121 YLSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVN 180

Query: 164 AIYFKGNWKDKFMKEATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQG 223
           AIYFKG W++KF    T  +PF+L++    TV+MMYQ   F   ++++ + +VLELPY  
Sbjct: 181 AIYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVN 240

Query: 224 EELSMVILLPDDIEDESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYT 283
            +LSM+ILLP  I      LK+IE+QL     HEWT   N+   EV V LPRFKLE  Y 
Sbjct: 241 NKLSMIILLPVGI----ANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYE 296

Query: 284 LNSDLARLGVQDLFNSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATF 343
           LNS L  LGV DLFN  KADLSGMS  + +++SK +HKS+++V+EEGTEAAAAT      
Sbjct: 297 LNSLLKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAV 356

Query: 344 CMLMPEENFTADHPFLFFIRHNSSGSILFLGRFSSP 379
             L     F A+HPFLFFIRH  + +ILF G+ +SP
Sbjct: 357 KSLPMRAQFKANHPFLFFIRHTHTNTILFCGKLASP 392


>gi|167860126 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 5 [Homo sapiens]
          Length = 375

 Score =  314 bits (804), Expect = 1e-85
 Identities = 149/379 (39%), Positives = 237/379 (62%), Gaps = 4/379 (1%)

Query: 1   MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF 60
           M+ L  AN+ FA+DLF  L E  P GN+  SP  +S+++++  +G +G+TA ++ +  HF
Sbjct: 1   MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHF 60

Query: 61  NTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVD 120
             V++V   FQ++ +D+NK  + Y LKL  RLY +K+ N   EF+ ST++ Y  +L +VD
Sbjct: 61  ENVKDVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVD 120

Query: 121 FQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEAT 180
           F+   E+ +  IN  +K  T+G    +LA   V++ TK+++VNA YF G W  KF +  T
Sbjct: 121 FKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESET 180

Query: 181 TNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDES 240
              PFR+NK D K V+MM  +  F  G I+ + C+++ELP+Q + LSM ILLP D+EDES
Sbjct: 181 KECPFRVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDVEDES 240

Query: 241 TGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSS 300
           TGL+KIE+QL  E L +WT P  +   +V +S+P+FK+E+     + L  LG++ +F+  
Sbjct: 241 TGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSED 300

Query: 301 KADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTADHPFLF 360
            +D SGMS  + + +S ++HK  +E+ E+G ++           +L  ++   ADHPF++
Sbjct: 301 TSDFSGMSETKGVALSNVIHKVCLEITEDGGDSIEVPGA----RILQHKDELNADHPFIY 356

Query: 361 FIRHNSSGSILFLGRFSSP 379
            IRHN + +I+F G+F SP
Sbjct: 357 IIRHNKTRNIIFFGKFCSP 375


>gi|17998551 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 12 [Homo sapiens]
          Length = 405

 Score =  314 bits (804), Expect = 1e-85
 Identities = 166/405 (40%), Positives = 247/405 (60%), Gaps = 26/405 (6%)

Query: 1   MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF 60
           M+ L +ANT+F  DLF  + +++   NIF SP S+S+A+ MV LG R ++A Q+ +  HF
Sbjct: 1   MDSLVTANTKFCFDLFQEIGKDDRHKNIFFSPLSLSAALGMVRLGARSDSAHQIDEVLHF 60

Query: 61  NTVEEVHSR--------------------------FQSLNADINKRGASYILKLANRLYG 94
           N   +  S+                          F  L + +++    Y L +ANRLYG
Sbjct: 61  NEFSQNESKEPDPCLKSNKQKAGSLNNESGLVSCYFGQLLSKLDRIKTDYTLSIANRLYG 120

Query: 95  EKTYNFLPEFLVSTQKTYGADLASVDFQHASEDARKTINQWVKGQTEGKIPELLASGMVD 154
           E+ +    E+L    + Y   + SVDFQ   E +R+ IN WV+ Q++GKI EL +   ++
Sbjct: 121 EQEFPICQEYLDGVIQFYHTTIESVDFQKNPEKSRQEINFWVECQSQGKIKELFSKDAIN 180

Query: 155 NMTKLVLVNAIYFKGNWKDKFMKEATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKC 214
             T LVLVNA+YFK  W+  F  E T +APF LN  + K+VKMM QK  +  G+IE++K 
Sbjct: 181 AETVLVLVNAVYFKAKWETYFDHENTVDAPFCLNANENKSVKMMTQKGLYRIGFIEEVKA 240

Query: 215 RVLELPYQGEELSMVILLPDDIEDESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLP 274
           ++LE+ Y   +LSM +LLP   +D   GL+++E ++T EK+  W+  EN+    V +S P
Sbjct: 241 QILEMRYTKGKLSMFVLLPSHSKDNLKGLEELERKITYEKMVAWSSSENMSEESVVLSFP 300

Query: 275 RFKLEESYTLNSDLARLGVQDLFNSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAA 334
           RF LE+SY LNS L  +G+ D+F+ ++ADL+G+S + ++++SKI+HK+FVEV+E GT+AA
Sbjct: 301 RFTLEDSYDLNSILQDMGITDIFDETRADLTGISPSPNLYLSKIIHKTFVEVDENGTQAA 360

Query: 335 AATAGIATFCMLMPEENFTADHPFLFFIRHNSSGSILFLGRFSSP 379
           AAT  + +   L     F A+HPFLFFIRHN + +ILF GR  SP
Sbjct: 361 AATGAVVSERSLRSWVEFNANHPFLFFIRHNKTQTILFYGRVCSP 405


>gi|92859634 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 7 [Homo sapiens]
          Length = 380

 Score =  277 bits (709), Expect = 1e-74
 Identities = 150/389 (38%), Positives = 224/389 (57%), Gaps = 19/389 (4%)

Query: 1   MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF 60
           M  L++AN  F  +LF  + +N   GN+F S  S+ +A+A+V LG + ++ +Q+ K  H 
Sbjct: 1   MASLAAANAEFCFNLFREMDDNQGNGNVFFSSLSLFAALALVRLGAQDDSLSQIDKLLHV 60

Query: 61  NTVEE----------VHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQK 110
           NT             + S+ + + +DIN     Y L + N L+ EK Y F  +++   +K
Sbjct: 61  NTASGYGNSSNSQSGLQSQLKRVFSDINASHKDYDLSIVNGLFAEKVYGFHKDYIECAEK 120

Query: 111 TYGADLASVDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGN 170
            Y A +  VDF +  ED R+ IN+WV+ +T GKI  ++  G + +   +VLVNA+YFKG 
Sbjct: 121 LYDAKVERVDFTNHLEDTRRNINKWVENETHGKIKNVIGEGGISSSAVMVLVNAVYFKGK 180

Query: 171 WKDKFMKEATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVI 230
           W+  F K  T N  F+  K   K V MM+Q++KF    IED   ++LEL Y G  ++M +
Sbjct: 181 WQSAFTKSETINCHFKSPKCSGKAVAMMHQERKFNLSVIEDPSMKILELRYNG-GINMYV 239

Query: 231 LLPDDIEDESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLAR 290
           LLP++       L +IE +LT + L EWT P  +    V V  P+FK+E++Y +   L  
Sbjct: 240 LLPEN------DLSEIENKLTFQNLMEWTNPRRMTSKYVEVFFPQFKIEKNYEMKQYLRA 293

Query: 291 LGVQDLFNSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEE 350
           LG++D+F+ SKADLSG++    ++IS+++HKS++EV EEGTEA AAT        L    
Sbjct: 294 LGLKDIFDESKADLSGIASGGRLYISRMMHKSYIEVTEEGTEATAATGSNIVEKQLPQST 353

Query: 351 NFTADHPFLFFIRHNSSGSILFLGRFSSP 379
            F ADHPFLF IR +    ILF G+ S P
Sbjct: 354 LFRADHPFLFVIRKDD--IILFSGKVSCP 380


>gi|4505149 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 7 [Homo sapiens]
          Length = 380

 Score =  277 bits (709), Expect = 1e-74
 Identities = 150/389 (38%), Positives = 224/389 (57%), Gaps = 19/389 (4%)

Query: 1   MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF 60
           M  L++AN  F  +LF  + +N   GN+F S  S+ +A+A+V LG + ++ +Q+ K  H 
Sbjct: 1   MASLAAANAEFCFNLFREMDDNQGNGNVFFSSLSLFAALALVRLGAQDDSLSQIDKLLHV 60

Query: 61  NTVEE----------VHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQK 110
           NT             + S+ + + +DIN     Y L + N L+ EK Y F  +++   +K
Sbjct: 61  NTASGYGNSSNSQSGLQSQLKRVFSDINASHKDYDLSIVNGLFAEKVYGFHKDYIECAEK 120

Query: 111 TYGADLASVDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGN 170
            Y A +  VDF +  ED R+ IN+WV+ +T GKI  ++  G + +   +VLVNA+YFKG 
Sbjct: 121 LYDAKVERVDFTNHLEDTRRNINKWVENETHGKIKNVIGEGGISSSAVMVLVNAVYFKGK 180

Query: 171 WKDKFMKEATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVI 230
           W+  F K  T N  F+  K   K V MM+Q++KF    IED   ++LEL Y G  ++M +
Sbjct: 181 WQSAFTKSETINCHFKSPKCSGKAVAMMHQERKFNLSVIEDPSMKILELRYNG-GINMYV 239

Query: 231 LLPDDIEDESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLAR 290
           LLP++       L +IE +LT + L EWT P  +    V V  P+FK+E++Y +   L  
Sbjct: 240 LLPEN------DLSEIENKLTFQNLMEWTNPRRMTSKYVEVFFPQFKIEKNYEMKQYLRA 293

Query: 291 LGVQDLFNSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEE 350
           LG++D+F+ SKADLSG++    ++IS+++HKS++EV EEGTEA AAT        L    
Sbjct: 294 LGLKDIFDESKADLSGIASGGRLYISRMMHKSYIEVTEEGTEATAATGSNIVEKQLPQST 353

Query: 351 NFTADHPFLFFIRHNSSGSILFLGRFSSP 379
            F ADHPFLF IR +    ILF G+ S P
Sbjct: 354 LFRADHPFLFVIRKDD--IILFSGKVSCP 380


>gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo
           sapiens]
          Length = 464

 Score =  259 bits (661), Expect = 4e-69
 Identities = 152/387 (39%), Positives = 231/387 (59%), Gaps = 17/387 (4%)

Query: 3   QLSSANTRFALDLFLALSEN-NPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHFN 61
           +LS AN+RFA   +  L+++ N   NIF+SP SIS+A AM  LG   +T  QL + F F+
Sbjct: 82  ELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFD 141

Query: 62  TVEE-----VHSRFQSLNADI-NKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGAD 115
           T+ E     +H  F  LN  +  K   S  L  ANRL+G+K+  F   +   ++  YGA 
Sbjct: 142 TISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQDISELVYGAK 201

Query: 116 LASVDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKF 175
           L  +DF+  +E +R  IN+WV  +TEG+I +++ S  ++ +T LVLVN IYFKG WK KF
Sbjct: 202 LQPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKGLWKSKF 261

Query: 176 MKEATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDD 235
             E T    F     +  +  MMYQ+ KF Y  + +   +VLELP++G++++MV++LP  
Sbjct: 262 SPENTRKELFYKADGESCSASMMYQEGKFRYRRVAE-GTQVLELPFKGDDITMVLILP-- 318

Query: 236 IEDESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQD 295
                  L K+E++LT E L EW   + L+ + + V +PRF++E+ ++L   L  +G+ D
Sbjct: 319 --KPEKSLAKVEKELTPEVLQEWL--DELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVD 374

Query: 296 LFNSSKADLSGM--SGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEE-NF 352
           LF+  K+ L G+   G  D+++S   HK+F+EVNEEG+EAAA+TA +     L P    F
Sbjct: 375 LFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTF 434

Query: 353 TADHPFLFFIRHNSSGSILFLGRFSSP 379
            A+ PFL FIR     +I+F+GR ++P
Sbjct: 435 KANRPFLVFIREVPLNTIIFMGRVANP 461


>gi|73623033 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 8 isoform b [Homo sapiens]
          Length = 242

 Score =  236 bits (602), Expect = 3e-62
 Identities = 120/238 (50%), Positives = 166/238 (69%), Gaps = 1/238 (0%)

Query: 1   MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF 60
           M+ L  AN  FA+ LF  L E + + N+F SP SISSA+AMVF+G +G+TAAQ+S+    
Sbjct: 1   MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60

Query: 61  NTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVD 120
               ++H  FQSL +++N+ G  Y+L+ ANRL+GEKT +FLP+F    QK Y A+L  + 
Sbjct: 61  YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS 120

Query: 121 FQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEAT 180
           F   +E+ RK IN WV  +TEGKI E+L +G VD +TKLVLVNAIYFKG W ++F ++ T
Sbjct: 121 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT 180

Query: 181 TNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIED 238
               F+ N +++KTV+MM+++ KF  GY +++  +VLELPY  EELSMVILLPDD  D
Sbjct: 181 RGMLFKTN-EEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTD 237


>gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member 2
           [Homo sapiens]
          Length = 405

 Score =  219 bits (557), Expect = 4e-57
 Identities = 132/378 (34%), Positives = 217/378 (57%), Gaps = 17/378 (4%)

Query: 8   NTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHFNTVEEVH 67
           NT FA+DL+  +S ++   NI  SP  I+  + MV LG +G    Q+ +T          
Sbjct: 26  NTEFAVDLYQEVSLSHK-DNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSAGE 84

Query: 68  SRF--QSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVDFQHAS 125
             F  +S  + I+++   +   LAN LY ++ +    ++L   ++ + + +  VDFQ A 
Sbjct: 85  EFFVLKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDFQDAK 144

Query: 126 EDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEATTNAPF 185
             A + I+ WV+ +T+GKI ++ +      +T+LVLVNAIYFKG+WK KF KE T    F
Sbjct: 145 ACA-EMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQLINF 203

Query: 186 RLNKKDRKTVK--MMYQKKKFAYGYIED--LKCRVLELPYQGEELSMVILLPDDIEDEST 241
              KK+  TVK  MM    +  YGY  +  L  +VLEL Y+G+E S++I+LP     E  
Sbjct: 204 --TKKNGSTVKIPMMKALLRTKYGYFSESSLNYQVLELSYKGDEFSLIIILPA----EGM 257

Query: 242 GLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSSK 301
            ++++E+ +T +++ +W      +  EV +SLPRFK+E+       L  L + ++F S  
Sbjct: 258 DIEEVEKLITAQQILKWLSEMQEE--EVEISLPRFKVEQKVDFKDVLYSLNITEIF-SGG 314

Query: 302 ADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTADHPFLFF 361
            DLSG++ + ++++S++  K F E+NE+G+EAA +T       M + +  F A+HPFLF 
Sbjct: 315 CDLSGITDSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSLAQSQFIANHPFLFI 374

Query: 362 IRHNSSGSILFLGRFSSP 379
           ++HN + SILF+GR ++P
Sbjct: 375 MKHNPTESILFMGRVTNP 392


>gi|170295807 neuroserpin precursor [Homo sapiens]
          Length = 410

 Score =  212 bits (540), Expect = 4e-55
 Identities = 126/376 (33%), Positives = 206/376 (54%), Gaps = 16/376 (4%)

Query: 12  ALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHFNTVE--EVHSR 69
           +++++  L       NI  SP SI+ AM M+ LG +G+T  ++  +  +++++  E  S 
Sbjct: 30  SVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKNGEEFSF 89

Query: 70  FQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVDFQHASEDAR 129
            +  +  +  + + Y++K+AN L+ +  ++   EFL   +K + A +  VDF      A 
Sbjct: 90  LKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQNVAVAN 149

Query: 130 KTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEATTNAPFRLNK 189
             IN+WV+  T   + +L++    D  T L L+NA+YFKGNWK +F  E T    F  + 
Sbjct: 150 Y-INKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTFSFTKDD 208

Query: 190 KDRKTVKMMYQKKKFAYGYIEDLK------CRVLELPYQGEELSMVILLPDDIEDESTGL 243
           +    + MMYQ+ +F YG   D         +VLE+PY+G+E+SM+++L      +   L
Sbjct: 209 ESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVL----SRQEVPL 264

Query: 244 KKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSSKAD 303
             +E  +  + + EW        +EV   LPRF +E+   L   L  LG+ ++F    A+
Sbjct: 265 ATLEPLVKAQLVEEWANSVKKQKVEVY--LPRFTVEQEIDLKDVLKALGITEIFIKD-AN 321

Query: 304 LSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTADHPFLFFIR 363
           L+G+S  ++IF+SK +HKSF+EVNEEG+EAAA +  IA   M +       DHPF F IR
Sbjct: 322 LTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFLIR 381

Query: 364 HNSSGSILFLGRFSSP 379
           +  +G+ILF+GR   P
Sbjct: 382 NRRTGTILFMGRVMHP 397


>gi|4826904 neuroserpin precursor [Homo sapiens]
          Length = 410

 Score =  212 bits (540), Expect = 4e-55
 Identities = 126/376 (33%), Positives = 206/376 (54%), Gaps = 16/376 (4%)

Query: 12  ALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHFNTVE--EVHSR 69
           +++++  L       NI  SP SI+ AM M+ LG +G+T  ++  +  +++++  E  S 
Sbjct: 30  SVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKNGEEFSF 89

Query: 70  FQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVDFQHASEDAR 129
            +  +  +  + + Y++K+AN L+ +  ++   EFL   +K + A +  VDF      A 
Sbjct: 90  LKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQNVAVAN 149

Query: 130 KTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEATTNAPFRLNK 189
             IN+WV+  T   + +L++    D  T L L+NA+YFKGNWK +F  E T    F  + 
Sbjct: 150 Y-INKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTFSFTKDD 208

Query: 190 KDRKTVKMMYQKKKFAYGYIEDLK------CRVLELPYQGEELSMVILLPDDIEDESTGL 243
           +    + MMYQ+ +F YG   D         +VLE+PY+G+E+SM+++L      +   L
Sbjct: 209 ESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVL----SRQEVPL 264

Query: 244 KKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSSKAD 303
             +E  +  + + EW        +EV   LPRF +E+   L   L  LG+ ++F    A+
Sbjct: 265 ATLEPLVKAQLVEEWANSVKKQKVEVY--LPRFTVEQEIDLKDVLKALGITEIFIKD-AN 321

Query: 304 LSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTADHPFLFFIR 363
           L+G+S  ++IF+SK +HKSF+EVNEEG+EAAA +  IA   M +       DHPF F IR
Sbjct: 322 LTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFLIR 381

Query: 364 HNSSGSILFLGRFSSP 379
           +  +G+ILF+GR   P
Sbjct: 382 NRRTGTILFMGRVMHP 397


>gi|50659080 serpin peptidase inhibitor, clade A, member 3 precursor
           [Homo sapiens]
          Length = 423

 Score =  207 bits (528), Expect = 1e-53
 Identities = 134/384 (34%), Positives = 210/384 (54%), Gaps = 20/384 (5%)

Query: 4   LSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHFNTV 63
           L+SAN  FA  L+  L    P  N+  SP SIS+A+A + LG    T  ++ K   FN  
Sbjct: 49  LASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLT 108

Query: 64  E----EVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASV 119
           E    E+H  FQ L   +N+      L + N ++ ++  + L  F    ++ YG++  + 
Sbjct: 109 ETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFAT 168

Query: 120 DFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEA 179
           DFQ ++  A+K IN +VK  T GKI +L+    +D+ T +VLVN I+FK  W+  F  + 
Sbjct: 169 DFQDSAA-AKKLINDYVKNGTRGKITDLIKD--LDSQTMMVLVNYIFFKAKWEMPFDPQD 225

Query: 180 TTNAPFRLNKKDRKTVKMM-YQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIED 238
           T  + F L+KK    V MM        Y   E+L C V+EL Y G   S + +LPD  + 
Sbjct: 226 THQSRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVELKYTGNA-SALFILPDQDK- 283

Query: 239 ESTGLKKIEEQLTLEKLHEWTKPENLDFIEVN-VSLPRFKLEESYTLNSDLARLGVQDLF 297
               ++++E  L  E L  W   ++L+F E+  + LP+F +   Y LN  L +LG+++ F
Sbjct: 284 ----MEEVEAMLLPETLKRWR--DSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAF 337

Query: 298 NSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTA--D 355
            +SKADLSG++GAR++ +S++VHK+ ++V EEGTEA+AATA   T    + E       +
Sbjct: 338 -TSKADLSGITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFN 396

Query: 356 HPFLFFIRHNSSGSILFLGRFSSP 379
            PFL  I    + +I F+ + ++P
Sbjct: 397 RPFLMIIVPTDTQNIFFMSKVTNP 420


>gi|73858566 heparin cofactor II precursor [Homo sapiens]
          Length = 499

 Score =  198 bits (503), Expect = 8e-51
 Identities = 128/389 (32%), Positives = 209/389 (53%), Gaps = 25/389 (6%)

Query: 1   MEQLSSANTRFALDLFLALSEN-NPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFH 59
           +++L+  N +FA +L+  L +  N   NIFI+P  IS+AM M+ LG +G T  Q+    H
Sbjct: 123 IQRLNILNAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILH 182

Query: 60  FNT---------VEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQK 110
           F           +  +H+ F+ L   + +R   Y L+  N LY +K +  L +F    ++
Sbjct: 183 FKDFVNASSKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVRE 242

Query: 111 TYGADLASVDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGN 170
            Y A+    DF   +  ++   N  +   T+G I + L +  +D  T+++++N IYFKG+
Sbjct: 243 YYFAEAQIADFSDPAFISKT--NNHIMKLTKGLIKDALEN--IDPATQMMILNCIYFKGS 298

Query: 171 WKDKFMKEATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVI 230
           W +KF  E T N  FRLN+++   V MM  K  F     ++L C +L+L Y G  +SM+I
Sbjct: 299 WVNKFPVEMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVG-GISMLI 357

Query: 231 LLPDDIEDESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLAR 290
           ++P     + +G+K +E QLT   +  W K  ++      V LP+FKLE++Y L   L  
Sbjct: 358 VVP----HKMSGMKTLEAQLTPRVVERWQK--SMTNRTREVLLPKFKLEKNYNLVESLKL 411

Query: 291 LGVQDLFNSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEE 350
           +G++ LF+ +  +++G+S  R I I    H+  + VNEEGT+A   T     F  L  + 
Sbjct: 412 MGIRMLFDKN-GNMAGISDQR-IAIDLFKHQGTITVNEEGTQATTVTT--VGFMPLSTQV 467

Query: 351 NFTADHPFLFFIRHNSSGSILFLGRFSSP 379
            FT D PFLF I  + +  +LF+GR ++P
Sbjct: 468 RFTVDRPFLFLIYEHRTSCLLFMGRVANP 496


>gi|110225347 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 9 isoform
           A [Homo sapiens]
          Length = 435

 Score =  194 bits (493), Expect = 1e-49
 Identities = 125/384 (32%), Positives = 207/384 (53%), Gaps = 19/384 (4%)

Query: 3   QLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHFNT 62
           Q+ S NT FA  L+  L    P+ NIF SP S+S+++AM+ LG    T  Q+ +   FN 
Sbjct: 61  QVYSLNTDFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNL 120

Query: 63  V----EEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLAS 118
                  +H  FQ L   +        LK+ + L+ +K       FL + ++ Y A++ S
Sbjct: 121 THTPESAIHQGFQHLVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFS 180

Query: 119 VDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKE 178
            DF + S  A+  IN  VK +T+GK+ +++    +D +T +VLVN I+FK  W+  F  E
Sbjct: 181 TDFSNPS-IAQARINSHVKKKTQGKVVDIIQG--LDLLTAMVLVNHIFFKAKWEKPFHPE 237

Query: 179 AT-TNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIE 237
            T  N PF + ++    V MM+QK++FA+G   +L C VL++ Y+G+ ++  +L      
Sbjct: 238 YTRKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVL------ 291

Query: 238 DESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLF 297
                ++++E+ L+   L +W+      +IE  V +PRF +  SY L + L ++G+Q++F
Sbjct: 292 PSKGKMRQLEQALSARTLRKWSHSLQKRWIE--VFIPRFSISASYNLETILPKMGIQNVF 349

Query: 298 NSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTA--D 355
           + + AD SG++    + +SK  HK+ ++V+EEGTEA AAT              FT   +
Sbjct: 350 DKN-ADFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFN 408

Query: 356 HPFLFFIRHNSSGSILFLGRFSSP 379
             FL  I + ++  ILFLG+  +P
Sbjct: 409 RTFLMMITNKATDGILFLGKVENP 432


>gi|211904156 plasminogen activator inhibitor type 1, member 2
           isoform c precursor [Homo sapiens]
          Length = 409

 Score =  189 bits (481), Expect = 3e-48
 Identities = 128/386 (33%), Positives = 201/386 (52%), Gaps = 22/386 (5%)

Query: 1   MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF 60
           +E+L S NT   + +F  + ++ P  NI ISP  I+S + M+ LG  G T  QL+    +
Sbjct: 39  LEELGS-NT--GIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRY 95

Query: 61  NTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVD 120
             V  V    + +N  I  +    I+ +AN ++ +        F+   +  +  ++ +V+
Sbjct: 96  G-VNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVN 154

Query: 121 FQHASEDARKTINQWVKGQTEGKIPELLASGMVDN-MTKLVLVNAIYFKGNWKDKFMKEA 179
           F+  +  A  +IN WVK +T   I  LL+  ++D  +T+LVLVNA+YFKG WK +F  E 
Sbjct: 155 FEDPAS-ACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPEN 213

Query: 180 TTNAPFRLNKKDRKTVKMMYQKKKFAYGYIE---DLKCRVLELPYQGEELSMVILLPDDI 236
           T    F         V M+ Q   F  G      DL    +ELPY GE +SM+I LP + 
Sbjct: 214 TKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTE- 272

Query: 237 EDESTGLKKIEEQLTLEKLHEWTK---PENLDFIEVNVSLPRFKLEESYTLNSDLARLGV 293
              ST L  I   ++ + +  W     P+      V V LP+F       L   L  LG+
Sbjct: 273 --SSTPLSAIIPHISTKTIDSWMSIMVPKR-----VQVILPKFTAVAQTDLKEPLKVLGI 325

Query: 294 QDLFNSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFT 353
            D+F+SSKA+ + ++ + ++ +S I+ K+ +EV+E+GT+A+AAT  I       P   F 
Sbjct: 326 TDMFDSSKANFAKITRSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSPPW--FI 383

Query: 354 ADHPFLFFIRHNSSGSILFLGRFSSP 379
            D PFLFFIRHN +G++LF+G+ + P
Sbjct: 384 VDRPFLFFIRHNPTGAVLFMGQINKP 409


>gi|211904154 plasminogen activator inhibitor type 1, member 2
           isoform b precursor [Homo sapiens]
          Length = 397

 Score =  189 bits (481), Expect = 3e-48
 Identities = 128/386 (33%), Positives = 201/386 (52%), Gaps = 22/386 (5%)

Query: 1   MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF 60
           +E+L S NT   + +F  + ++ P  NI ISP  I+S + M+ LG  G T  QL+    +
Sbjct: 27  LEELGS-NT--GIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRY 83

Query: 61  NTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVD 120
             V  V    + +N  I  +    I+ +AN ++ +        F+   +  +  ++ +V+
Sbjct: 84  G-VNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVN 142

Query: 121 FQHASEDARKTINQWVKGQTEGKIPELLASGMVDN-MTKLVLVNAIYFKGNWKDKFMKEA 179
           F+  +  A  +IN WVK +T   I  LL+  ++D  +T+LVLVNA+YFKG WK +F  E 
Sbjct: 143 FEDPAS-ACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPEN 201

Query: 180 TTNAPFRLNKKDRKTVKMMYQKKKFAYGYIE---DLKCRVLELPYQGEELSMVILLPDDI 236
           T    F         V M+ Q   F  G      DL    +ELPY GE +SM+I LP + 
Sbjct: 202 TKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTE- 260

Query: 237 EDESTGLKKIEEQLTLEKLHEWTK---PENLDFIEVNVSLPRFKLEESYTLNSDLARLGV 293
              ST L  I   ++ + +  W     P+      V V LP+F       L   L  LG+
Sbjct: 261 --SSTPLSAIIPHISTKTIDSWMSIMVPKR-----VQVILPKFTAVAQTDLKEPLKVLGI 313

Query: 294 QDLFNSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFT 353
            D+F+SSKA+ + ++ + ++ +S I+ K+ +EV+E+GT+A+AAT  I       P   F 
Sbjct: 314 TDMFDSSKANFAKITRSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSPPW--FI 371

Query: 354 ADHPFLFFIRHNSSGSILFLGRFSSP 379
            D PFLFFIRHN +G++LF+G+ + P
Sbjct: 372 VDRPFLFFIRHNPTGAVLFMGQINKP 397


>gi|211904152 plasminogen activator inhibitor type 1, member 2
           isoform b precursor [Homo sapiens]
          Length = 397

 Score =  189 bits (481), Expect = 3e-48
 Identities = 128/386 (33%), Positives = 201/386 (52%), Gaps = 22/386 (5%)

Query: 1   MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF 60
           +E+L S NT   + +F  + ++ P  NI ISP  I+S + M+ LG  G T  QL+    +
Sbjct: 27  LEELGS-NT--GIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRY 83

Query: 61  NTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVD 120
             V  V    + +N  I  +    I+ +AN ++ +        F+   +  +  ++ +V+
Sbjct: 84  G-VNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVN 142

Query: 121 FQHASEDARKTINQWVKGQTEGKIPELLASGMVDN-MTKLVLVNAIYFKGNWKDKFMKEA 179
           F+  +  A  +IN WVK +T   I  LL+  ++D  +T+LVLVNA+YFKG WK +F  E 
Sbjct: 143 FEDPAS-ACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPEN 201

Query: 180 TTNAPFRLNKKDRKTVKMMYQKKKFAYGYIE---DLKCRVLELPYQGEELSMVILLPDDI 236
           T    F         V M+ Q   F  G      DL    +ELPY GE +SM+I LP + 
Sbjct: 202 TKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTE- 260

Query: 237 EDESTGLKKIEEQLTLEKLHEWTK---PENLDFIEVNVSLPRFKLEESYTLNSDLARLGV 293
              ST L  I   ++ + +  W     P+      V V LP+F       L   L  LG+
Sbjct: 261 --SSTPLSAIIPHISTKTIDSWMSIMVPKR-----VQVILPKFTAVAQTDLKEPLKVLGI 313

Query: 294 QDLFNSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFT 353
            D+F+SSKA+ + ++ + ++ +S I+ K+ +EV+E+GT+A+AAT  I       P   F 
Sbjct: 314 TDMFDSSKANFAKITRSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSPPW--FI 371

Query: 354 ADHPFLFFIRHNSSGSILFLGRFSSP 379
            D PFLFFIRHN +G++LF+G+ + P
Sbjct: 372 VDRPFLFFIRHNPTGAVLFMGQINKP 397


>gi|194018472 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 5 [Homo
           sapiens]
          Length = 406

 Score =  189 bits (481), Expect = 3e-48
 Identities = 128/379 (33%), Positives = 205/379 (54%), Gaps = 20/379 (5%)

Query: 6   SANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHFN---- 61
           S+   F  DL+ AL+   P+ +IF SP SIS ++AM+ LG   +T  Q+ +    N    
Sbjct: 43  SSRRDFTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKS 102

Query: 62  TVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVDF 121
           + +E+H  FQ L  ++N+    + L L N L+ +   +    F+ + +  Y AD    +F
Sbjct: 103 SEKELHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNF 162

Query: 122 QHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEATT 181
           +  S  A K IN +V  QT+GKI +LL +  +D+   +++VN I+FK  W+  F  + T 
Sbjct: 163 RD-SAGAMKQINDYVAKQTKGKIVDLLKN--LDSNAVVIMVNYIFFKAKWETSFNHKGTQ 219

Query: 182 NAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDEST 241
              F +  +    V MM ++ ++ Y    +L CRV+ +PYQG   ++ IL          
Sbjct: 220 EQDFYVTSETVVRVPMMSREDQYHYLLDRNLSCRVVGVPYQGNATALFIL------PSEG 273

Query: 242 GLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSSK 301
            ++++E  L+ + L +W K      +E  + LP+F +E SY L   L  LG+ ++F +S 
Sbjct: 274 KMQQVENGLSEKTLRKWLKMFKKRQLE--LYLPKFSIEGSYQLEKVLPSLGISNVF-TSH 330

Query: 302 ADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATF-CMLMPEENFTADHPFLF 360
           ADLSG+S   +I +S++VHK+ VEV+E GT AAAAT  I TF    +  +    + PFL 
Sbjct: 331 ADLSGISNHSNIQVSEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLM 390

Query: 361 FIRHNSSGSILFLGRFSSP 379
           FI  N   +ILFLG+ + P
Sbjct: 391 FIVDN---NILFLGKVNRP 406


>gi|24307907 plasminogen activator inhibitor type 1, member 2
           isoform a precursor [Homo sapiens]
          Length = 398

 Score =  188 bits (477), Expect = 8e-48
 Identities = 129/387 (33%), Positives = 202/387 (52%), Gaps = 23/387 (5%)

Query: 1   MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF 60
           +E+L S NT   + +F  + ++ P  NI ISP  I+S + M+ LG  G T  QL+    +
Sbjct: 27  LEELGS-NT--GIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRY 83

Query: 61  NTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVD 120
             V  V    + +N  I  +    I+ +AN ++ +        F+   +  +  ++ +V+
Sbjct: 84  G-VNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVN 142

Query: 121 FQHASEDARKTINQWVKGQTEGKIPELLASGMVDN-MTKLVLVNAIYFKGNWKDKFMKEA 179
           F+  +  A  +IN WVK +T   I  LL+  ++D  +T+LVLVNA+YFKG WK +F  E 
Sbjct: 143 FEDPAS-ACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPEN 201

Query: 180 TTNAPFRLNKKDRKTVKMMYQKKKFAYGYIE---DLKCRVLELPYQGEELSMVILLPDDI 236
           T    F         V M+ Q   F  G      DL    +ELPY GE +SM+I LP + 
Sbjct: 202 TKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTE- 260

Query: 237 EDESTGLKKIEEQLTLEKLHEWTK---PENLDFIEVNVSLPRFKLEESYTLNSDLARLGV 293
              ST L  I   ++ + +  W     P+      V V LP+F       L   L  LG+
Sbjct: 261 --SSTPLSAIIPHISTKTIDSWMSIMVPKR-----VQVILPKFTAVAQTDLKEPLKVLGI 313

Query: 294 QDLFNSSKADLSGMS-GARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENF 352
            D+F+SSKA+ + ++ G+ ++ +S I+ K+ +EV+E+GT+A+AAT  I       P   F
Sbjct: 314 TDMFDSSKANFAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSPPW--F 371

Query: 353 TADHPFLFFIRHNSSGSILFLGRFSSP 379
             D PFLFFIRHN +G++LF+G+ + P
Sbjct: 372 IVDRPFLFFIRHNPTGAVLFMGQINKP 398


>gi|32454741 serine (or cysteine) proteinase inhibitor, clade H,
           member 1 precursor [Homo sapiens]
          Length = 418

 Score =  182 bits (463), Expect = 3e-46
 Identities = 113/379 (29%), Positives = 203/379 (53%), Gaps = 15/379 (3%)

Query: 4   LSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHFNTV 63
           L+  +   A  L+ A++++    NI +SP  ++S++ +V LG +  TA+Q         +
Sbjct: 43  LAERSAGLAFSLYQAMAKDQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQL 102

Query: 64  --EEVHSRFQSLNADINKRGASYIL-KLANRLYGEKTYNFLPEFLVSTQKTYGADLASVD 120
             EEVH+    L   ++   A  +  KL +RLYG  + +F  +F+ S+++ Y  + + ++
Sbjct: 103 RDEEVHAGLGELLRSLSNSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKIN 162

Query: 121 FQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEAT 180
           F+     A ++IN+W    T+GK+PE+     V+     +LVNA++FK +W +KF  +  
Sbjct: 163 FRD-KRSALQSINEWAAQTTDGKLPEVTKD--VERTDGALLVNAMFFKPHWDEKFHHKMV 219

Query: 181 TNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDES 240
            N  F + +     V MM++   + Y   E  K +++E+P   +  S++IL+P  +E   
Sbjct: 220 DNRGFMVTRSYTVGVMMMHRTGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEP-- 277

Query: 241 TGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSS 300
             L+++E+ LT E+L  W     +    V +SLP+  +E ++ L   LA LG+ +  + +
Sbjct: 278 --LERLEKLLTKEQLKIWMG--KMQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKN 333

Query: 301 KADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTADHPFLF 360
           KADLS MSG +D++++ + H +  E++ +G        G      L   + F ADHPF+F
Sbjct: 334 KADLSRMSGKKDLYLASVFHATAFELDTDGNPFDQDIYGREE---LRSPKLFYADHPFIF 390

Query: 361 FIRHNSSGSILFLGRFSSP 379
            +R   SGS+LF+GR   P
Sbjct: 391 LVRDTQSGSLLFIGRLVRP 409


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.376 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,505,530
Number of Sequences: 37866
Number of extensions: 516077
Number of successful extensions: 1597
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 60
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1290
Number of HSP's gapped (non-prelim): 76
length of query: 379
length of database: 18,247,518
effective HSP length: 104
effective length of query: 275
effective length of database: 14,309,454
effective search space: 3935099850
effective search space used: 3935099850
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.