Guide to the Human Genome
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Search of human proteins with 6041665

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|6041665 1-acylglycerol-3-phosphate O-acyltransferase 2
isoform a [Homo sapiens]
         (278 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|6041665 1-acylglycerol-3-phosphate O-acyltransferase 2 isofor...   553   e-158
gi|69122971 1-acylglycerol-3-phosphate O-acyltransferase 2 isofo...   470   e-133
gi|5453718 1-acylglycerol-3-phosphate O-acyltransferase 1 [Homo ...   250   8e-67
gi|15100175 1-acylglycerol-3-phosphate O-acyltransferase 1 [Homo...   250   8e-67
gi|87116681 lysophosphatidylcholine acyltransferase 4 [Homo sapi...    44   1e-04
gi|33946291 lysophosphatidylcholine acyltransferase 1 [Homo sapi...    37   0.015
gi|47086907 lysophosphatidylcholine acyltransferase 2 [Homo sapi...    32   0.80 
gi|30520329 lysophosphatidic acid acyltransferase zeta precursor...    31   1.0  
gi|21362092 1-acylglycerol-3-phosphate O-acyltransferase 9 [Homo...    30   1.8  
gi|44771201 integrator complex subunit 5 [Homo sapiens]                28   6.8  
gi|215598824 ankyrin repeat and SOCS box-containing 10 isoform 2...    28   8.8  

>gi|6041665 1-acylglycerol-3-phosphate O-acyltransferase 2 isoform a
           [Homo sapiens]
          Length = 278

 Score =  553 bits (1426), Expect = e-158
 Identities = 278/278 (100%), Positives = 278/278 (100%)

Query: 1   MELWPCLAAALLLLLLLVQLSRAAEFYAKVALYCALCFTVSAVASLVCLLRHGGRTVENM 60
           MELWPCLAAALLLLLLLVQLSRAAEFYAKVALYCALCFTVSAVASLVCLLRHGGRTVENM
Sbjct: 1   MELWPCLAAALLLLLLLVQLSRAAEFYAKVALYCALCFTVSAVASLVCLLRHGGRTVENM 60

Query: 61  SIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLPERCVQIAK 120
           SIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLPERCVQIAK
Sbjct: 61  SIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLPERCVQIAK 120

Query: 121 RELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENLKVWIYPEGTRNDNGD 180
           RELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENLKVWIYPEGTRNDNGD
Sbjct: 121 RELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENLKVWIYPEGTRNDNGD 180

Query: 181 LLPFKKGAFYLAVQAQVPIVPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIPTSGLTAAD 240
           LLPFKKGAFYLAVQAQVPIVPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIPTSGLTAAD
Sbjct: 181 LLPFKKGAFYLAVQAQVPIVPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIPTSGLTAAD 240

Query: 241 VPALVDTCHRAMRTTFLHISKTPQENGATAGSGVQPAQ 278
           VPALVDTCHRAMRTTFLHISKTPQENGATAGSGVQPAQ
Sbjct: 241 VPALVDTCHRAMRTTFLHISKTPQENGATAGSGVQPAQ 278


>gi|69122971 1-acylglycerol-3-phosphate O-acyltransferase 2 isoform
           b [Homo sapiens]
          Length = 246

 Score =  470 bits (1210), Expect = e-133
 Identities = 246/278 (88%), Positives = 246/278 (88%), Gaps = 32/278 (11%)

Query: 1   MELWPCLAAALLLLLLLVQLSRAAEFYAKVALYCALCFTVSAVASLVCLLRHGGRTVENM 60
           MELWPCLAAALLLLLLLVQLSRAAEFYAKVALYCALCFTVSAVASLVCLLRHGGRTVENM
Sbjct: 1   MELWPCLAAALLLLLLLVQLSRAAEFYAKVALYCALCFTVSAVASLVCLLRHGGRTVENM 60

Query: 61  SIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLPERCVQIAK 120
           SIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLPERCVQIAK
Sbjct: 61  SIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLPERCVQIAK 120

Query: 121 RELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENLKVWIYPEGTRNDNGD 180
           RELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVREN                
Sbjct: 121 RELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVREN---------------- 164

Query: 181 LLPFKKGAFYLAVQAQVPIVPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIPTSGLTAAD 240
                           VPIVPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIPTSGLTAAD
Sbjct: 165 ----------------VPIVPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIPTSGLTAAD 208

Query: 241 VPALVDTCHRAMRTTFLHISKTPQENGATAGSGVQPAQ 278
           VPALVDTCHRAMRTTFLHISKTPQENGATAGSGVQPAQ
Sbjct: 209 VPALVDTCHRAMRTTFLHISKTPQENGATAGSGVQPAQ 246


>gi|5453718 1-acylglycerol-3-phosphate O-acyltransferase 1 [Homo
           sapiens]
          Length = 283

 Score =  250 bits (639), Expect = 8e-67
 Identities = 131/275 (47%), Positives = 181/275 (65%), Gaps = 10/275 (3%)

Query: 1   MELWPCLAAALLLLLLLVQL--------SRAAEFYAKVALYCALCFTVSAVASLVCLLRH 52
           M+LWP     LLLL LL+          S +A+++ K+A Y      ++ +A  VC +R 
Sbjct: 1   MDLWPGAWMLLLLLFLLLLFLLPTLWFCSPSAKYFFKMAFYNGWILFLAVLAIPVCAVR- 59

Query: 53  GGRTVENMSIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLP 112
            GR VENM I+   +   KY YG+R EVR       ++P V+VSNHQS LD++G+MEVLP
Sbjct: 60  -GRNVENMKILRLMLLHIKYLYGIRVEVRGAHHFPPSQPYVVVSNHQSSLDLLGMMEVLP 118

Query: 113 ERCVQIAKRELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENLKVWIYPE 172
            RCV IAKRELL+ G  GL  +L GV FI+R+R+  A++VM+++ + ++ ++++VW++PE
Sbjct: 119 GRCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVMSEVAQTLLTQDVRVWVFPE 178

Query: 173 GTRNDNGDLLPFKKGAFYLAVQAQVPIVPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIP 232
           GTRN NG +LPFK+GAF+LAVQAQVPIVP+V SS+  FY  K++ FTSG   V+VL  +P
Sbjct: 179 GTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMSSYQDFYCKKERRFTSGQCQVRVLPPVP 238

Query: 233 TSGLTAADVPALVDTCHRAMRTTFLHISKTPQENG 267
           T GLT  DVPAL D    +M T F  IS   +  G
Sbjct: 239 TEGLTPDDVPALADRVRHSMLTVFREISTDGRGGG 273


>gi|15100175 1-acylglycerol-3-phosphate O-acyltransferase 1 [Homo
           sapiens]
          Length = 283

 Score =  250 bits (639), Expect = 8e-67
 Identities = 131/275 (47%), Positives = 181/275 (65%), Gaps = 10/275 (3%)

Query: 1   MELWPCLAAALLLLLLLVQL--------SRAAEFYAKVALYCALCFTVSAVASLVCLLRH 52
           M+LWP     LLLL LL+          S +A+++ K+A Y      ++ +A  VC +R 
Sbjct: 1   MDLWPGAWMLLLLLFLLLLFLLPTLWFCSPSAKYFFKMAFYNGWILFLAVLAIPVCAVR- 59

Query: 53  GGRTVENMSIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLP 112
            GR VENM I+   +   KY YG+R EVR       ++P V+VSNHQS LD++G+MEVLP
Sbjct: 60  -GRNVENMKILRLMLLHIKYLYGIRVEVRGAHHFPPSQPYVVVSNHQSSLDLLGMMEVLP 118

Query: 113 ERCVQIAKRELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENLKVWIYPE 172
            RCV IAKRELL+ G  GL  +L GV FI+R+R+  A++VM+++ + ++ ++++VW++PE
Sbjct: 119 GRCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVMSEVAQTLLTQDVRVWVFPE 178

Query: 173 GTRNDNGDLLPFKKGAFYLAVQAQVPIVPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIP 232
           GTRN NG +LPFK+GAF+LAVQAQVPIVP+V SS+  FY  K++ FTSG   V+VL  +P
Sbjct: 179 GTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMSSYQDFYCKKERRFTSGQCQVRVLPPVP 238

Query: 233 TSGLTAADVPALVDTCHRAMRTTFLHISKTPQENG 267
           T GLT  DVPAL D    +M T F  IS   +  G
Sbjct: 239 TEGLTPDDVPALADRVRHSMLTVFREISTDGRGGG 273


>gi|87116681 lysophosphatidylcholine acyltransferase 4 [Homo
           sapiens]
          Length = 524

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 44/179 (24%), Positives = 79/179 (44%), Gaps = 10/179 (5%)

Query: 55  RTVENMSIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEV-LPE 113
           +TV +  ++G     F     LR  VR  R  +   P ++ + H +  D + L+   LP+
Sbjct: 86  KTVCHNGVLGLSRLLFFLLGFLRIRVRGQRASRLQAPVLVAAPHSTFFDPIVLLPCDLPK 145

Query: 114 RCVQIAKRELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENL--KVWIYP 171
               +++ E L +  +G ++       ++R   ++   V+ ++  R        +V  +P
Sbjct: 146 ---VVSRAENLSVPVIGALLRFNQAILVSRHDPASRRRVVEEVRRRATSGGKWPQVLFFP 202

Query: 172 EGTRNDNGDLLPFKKGAFYLAVQAQVPIVPVVYSSFSSFYNTKKKFFTSGTVTVQVLEA 230
           EGT ++   LL FK GAF     A VP+ PV+    +S   T   +   G + V  L A
Sbjct: 203 EGTCSNKKALLKFKPGAFI----AGVPVQPVLIRYPNSLDTTSWAWRGPGVLKVLWLTA 257


>gi|33946291 lysophosphatidylcholine acyltransferase 1 [Homo
           sapiens]
          Length = 534

 Score = 37.4 bits (85), Expect = 0.015
 Identities = 37/142 (26%), Positives = 59/142 (41%), Gaps = 16/142 (11%)

Query: 65  WFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLPERCVQIAKRELL 124
           WF   F      R  V+  + L      + ++ H S  D + +   +    ++   R++ 
Sbjct: 107 WFAGGFH-----RVAVKGRQALPTEAAILTLAPHSSYFDAIPVTMTMSSIVMKAESRDIP 161

Query: 125 FLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENLK---VWIYPEGTRNDNGDL 181
             G   LI Y+  VF     + S   TV  +  +R  + N K   + I+PEGT  +   L
Sbjct: 162 IWGT--LIQYIRPVFVSRSDQDSRRKTV--EEIKRRAQSNGKWPQIMIFPEGTCTNRTCL 217

Query: 182 LPFKKGAFYLAVQAQVPIVPVV 203
           + FK GAF        P+ PVV
Sbjct: 218 ITFKPGAFI----PGAPVQPVV 235


>gi|47086907 lysophosphatidylcholine acyltransferase 2 [Homo
           sapiens]
          Length = 544

 Score = 31.6 bits (70), Expect = 0.80
 Identities = 37/181 (20%), Positives = 76/181 (41%), Gaps = 13/181 (7%)

Query: 30  VALYCALCFTVSAVASLVC--LLRH---GGRTVENMSIIGWFVRSFKYFYGLRFEVRDPR 84
           VAL   L +  +A++++ C   L H   G R     + + +  R+  +  G    V+   
Sbjct: 73  VALILLLAWPFAAISTVCCPEKLTHPITGWRRKITQTALKFLGRAMFFSMGFIVAVKGKI 132

Query: 85  RLQEARPCVIVSNHQSILDMMGLMEVLPERCVQIAKRELLFLGPVGLIMYLGGVFFINRQ 144
                 P  + + H +  D  G+  V+      +++ E   +  +G ++       ++R 
Sbjct: 133 ASPLEAPVFVAAPHSTFFD--GIACVVAGLPSMVSRNENAQVPLIGRLLRAVQPVLVSRV 190

Query: 145 RSSTAMTVMADLGERMVR--ENLKVWIYPEGTRNDNGDLLPFKKGAFYLAVQAQVPIVPV 202
              +    + ++ +R     E  ++ ++PEGT  +   L+ FK GAF       VP+ PV
Sbjct: 191 DPDSRKNTINEIIKRTTSGGEWPQILVFPEGTCTNRSCLITFKPGAFI----PGVPVQPV 246

Query: 203 V 203
           +
Sbjct: 247 L 247


>gi|30520329 lysophosphatidic acid acyltransferase zeta precursor
           [Homo sapiens]
          Length = 456

 Score = 31.2 bits (69), Expect = 1.0
 Identities = 15/54 (27%), Positives = 27/54 (50%)

Query: 162 RENLKVWIYPEGTRNDNGDLLPFKKGAFYLAVQAQVPIVPVVYSSFSSFYNTKK 215
           +  L + I+PEGT  +N  ++ FKKG+F +        +        +F+N+ K
Sbjct: 312 KSKLPILIFPEGTCINNTSVMMFKKGSFEIGATVYPVAIKYDPQFGDAFWNSSK 365


>gi|21362092 1-acylglycerol-3-phosphate O-acyltransferase 9 [Homo
           sapiens]
          Length = 434

 Score = 30.4 bits (67), Expect = 1.8
 Identities = 15/54 (27%), Positives = 28/54 (51%)

Query: 162 RENLKVWIYPEGTRNDNGDLLPFKKGAFYLAVQAQVPIVPVVYSSFSSFYNTKK 215
           ++ L + I+PEGT  +N  ++ FKKG+F +        +        +F+N+ K
Sbjct: 293 KKKLPILIFPEGTCINNTSVMMFKKGSFEIGGTIHPVAIKYNPQFGDAFWNSSK 346


>gi|44771201 integrator complex subunit 5 [Homo sapiens]
          Length = 1019

 Score = 28.5 bits (62), Expect = 6.8
 Identities = 15/51 (29%), Positives = 21/51 (41%), Gaps = 2/51 (3%)

Query: 224 TVQVLEAIPTSGLTAADVPALVDTCHRAMRTTFLHISKTPQENGATAGSGV 274
           T      I T GL   D   + + C R ++   LH+ K     G + G GV
Sbjct: 413 TAMPASVITTQGLAVPDT--VREACDRLIQLLLLHLQKLVHHRGGSPGEGV 461


>gi|215598824 ankyrin repeat and SOCS box-containing 10 isoform 2
           [Homo sapiens]
          Length = 474

 Score = 28.1 bits (61), Expect = 8.8
 Identities = 32/116 (27%), Positives = 47/116 (40%), Gaps = 10/116 (8%)

Query: 8   AAALLLLLLLVQLSRAAEFYAKVALYCALCFTVSAVAS-----LVCLLRHGGRTVENMSI 62
           AA + LLL     +   ++     L+CAL    +A+A      +  LL HG   V     
Sbjct: 352 AAVVELLLSCGVSANTMDYGGHTPLHCALQGPAAALAQSPEHVVRALLNHGAVRVWP--- 408

Query: 63  IGWFVRSFKYFYGLRFE-VRDPRRLQEARPCVIVSNHQSILDMMGLMEVLPERCVQ 117
            G   +  + FY   F  VR PR LQ    C + S+ +  L        LP R ++
Sbjct: 409 -GALPKKHQRFYSSLFALVRQPRSLQHLSRCALRSHLEGSLPQALPRLPLPPRLLR 463


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.138    0.417 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,425,682
Number of Sequences: 37866
Number of extensions: 368070
Number of successful extensions: 1053
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1040
Number of HSP's gapped (non-prelim): 12
length of query: 278
length of database: 18,247,518
effective HSP length: 101
effective length of query: 177
effective length of database: 14,423,052
effective search space: 2552880204
effective search space used: 2552880204
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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