Guide to the Human Genome
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Search of human proteins with 60302912

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|60302912 integral membrane protein 2C isoform 3 [Homo
sapiens]
         (220 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|60302912 integral membrane protein 2C isoform 3 [Homo sapiens]     446   e-126
gi|13569885 integral membrane protein 2C isoform 1 [Homo sapiens]     423   e-119
gi|60302914 integral membrane protein 2C isoform 2 [Homo sapiens]     328   2e-90
gi|11527402 integral membrane protein 2B [Homo sapiens]               203   8e-53
gi|4758224 integral membrane protein 2A [Homo sapiens]                159   1e-39
gi|59806343 leukocyte cell derived chemotaxin 1 isoform 2 precur...    29   2.8  
gi|5901932 leukocyte cell derived chemotaxin 1 isoform 1 precurs...    29   2.8  
gi|149773468 RAD51 associated protein 2 [Homo sapiens]                 29   3.6  
gi|156627559 tenomodulin [Homo sapiens]                                28   6.1  

>gi|60302912 integral membrane protein 2C isoform 3 [Homo sapiens]
          Length = 220

 Score =  446 bits (1146), Expect = e-126
 Identities = 220/220 (100%), Positives = 220/220 (100%)

Query: 1   MVKISFQPAVAGIKGDKADKASASAPAPASATEILLTPARLARDNFFRCGVLYEDSLSSQ 60
           MVKISFQPAVAGIKGDKADKASASAPAPASATEILLTPARLARDNFFRCGVLYEDSLSSQ
Sbjct: 1   MVKISFQPAVAGIKGDKADKASASAPAPASATEILLTPARLARDNFFRCGVLYEDSLSSQ 60

Query: 61  VRTQMELEEDVKIYLDENYERINVPVPQFGGGDPADIIHDFQRGLTAYHDISLDKCYVIE 120
           VRTQMELEEDVKIYLDENYERINVPVPQFGGGDPADIIHDFQRGLTAYHDISLDKCYVIE
Sbjct: 61  VRTQMELEEDVKIYLDENYERINVPVPQFGGGDPADIIHDFQRGLTAYHDISLDKCYVIE 120

Query: 121 LNTTIVLPPRNFWELLMNVKRGTYLPQTYIIQEEMVVTEHVSDKEALGSFIYHLCNGKDT 180
           LNTTIVLPPRNFWELLMNVKRGTYLPQTYIIQEEMVVTEHVSDKEALGSFIYHLCNGKDT
Sbjct: 121 LNTTIVLPPRNFWELLMNVKRGTYLPQTYIIQEEMVVTEHVSDKEALGSFIYHLCNGKDT 180

Query: 181 YRLRRRATRRRINKRGAKNCNAIRHFENTFVVETLICGVV 220
           YRLRRRATRRRINKRGAKNCNAIRHFENTFVVETLICGVV
Sbjct: 181 YRLRRRATRRRINKRGAKNCNAIRHFENTFVVETLICGVV 220


>gi|13569885 integral membrane protein 2C isoform 1 [Homo sapiens]
          Length = 267

 Score =  423 bits (1088), Expect = e-119
 Identities = 220/267 (82%), Positives = 220/267 (82%), Gaps = 47/267 (17%)

Query: 1   MVKISFQPAVAGIKGDKADKASASAPAPASATEILLTPAR-------------------- 40
           MVKISFQPAVAGIKGDKADKASASAPAPASATEILLTPAR                    
Sbjct: 1   MVKISFQPAVAGIKGDKADKASASAPAPASATEILLTPAREEQPPQHRSKRGGSVGGVCY 60

Query: 41  ---------------------------LARDNFFRCGVLYEDSLSSQVRTQMELEEDVKI 73
                                      LARDNFFRCGVLYEDSLSSQVRTQMELEEDVKI
Sbjct: 61  LSMGMVVLLMGLVFASVYIYRYFFLAQLARDNFFRCGVLYEDSLSSQVRTQMELEEDVKI 120

Query: 74  YLDENYERINVPVPQFGGGDPADIIHDFQRGLTAYHDISLDKCYVIELNTTIVLPPRNFW 133
           YLDENYERINVPVPQFGGGDPADIIHDFQRGLTAYHDISLDKCYVIELNTTIVLPPRNFW
Sbjct: 121 YLDENYERINVPVPQFGGGDPADIIHDFQRGLTAYHDISLDKCYVIELNTTIVLPPRNFW 180

Query: 134 ELLMNVKRGTYLPQTYIIQEEMVVTEHVSDKEALGSFIYHLCNGKDTYRLRRRATRRRIN 193
           ELLMNVKRGTYLPQTYIIQEEMVVTEHVSDKEALGSFIYHLCNGKDTYRLRRRATRRRIN
Sbjct: 181 ELLMNVKRGTYLPQTYIIQEEMVVTEHVSDKEALGSFIYHLCNGKDTYRLRRRATRRRIN 240

Query: 194 KRGAKNCNAIRHFENTFVVETLICGVV 220
           KRGAKNCNAIRHFENTFVVETLICGVV
Sbjct: 241 KRGAKNCNAIRHFENTFVVETLICGVV 267


>gi|60302914 integral membrane protein 2C isoform 2 [Homo sapiens]
          Length = 230

 Score =  328 bits (841), Expect = 2e-90
 Identities = 183/267 (68%), Positives = 183/267 (68%), Gaps = 84/267 (31%)

Query: 1   MVKISFQPAVAGIKGDKADKASASAPAPASATEILLTPAR-------------------- 40
           MVKISFQPAVAGIKGDKADKASASAPAPASATEILLTPAR                    
Sbjct: 1   MVKISFQPAVAGIKGDKADKASASAPAPASATEILLTPAREEQPPQHRSKRGGSVGGVCY 60

Query: 41  ---------------------------LARDNFFRCGVLYEDSLSSQVRTQMELEEDVKI 73
                                      LARDNFFRCGVLYEDSLSSQVRTQMELEEDVKI
Sbjct: 61  LSMGMVVLLMGLVFASVYIYRYFFLAQLARDNFFRCGVLYEDSLSSQVRTQMELEEDVKI 120

Query: 74  YLDENYERINVPVPQFGGGDPADIIHDFQRGLTAYHDISLDKCYVIELNTTIVLPPRNFW 133
           YLDENYERINVPVPQFGGGDPADIIHDFQR                              
Sbjct: 121 YLDENYERINVPVPQFGGGDPADIIHDFQR------------------------------ 150

Query: 134 ELLMNVKRGTYLPQTYIIQEEMVVTEHVSDKEALGSFIYHLCNGKDTYRLRRRATRRRIN 193
                  RGTYLPQTYIIQEEMVVTEHVSDKEALGSFIYHLCNGKDTYRLRRRATRRRIN
Sbjct: 151 -------RGTYLPQTYIIQEEMVVTEHVSDKEALGSFIYHLCNGKDTYRLRRRATRRRIN 203

Query: 194 KRGAKNCNAIRHFENTFVVETLICGVV 220
           KRGAKNCNAIRHFENTFVVETLICGVV
Sbjct: 204 KRGAKNCNAIRHFENTFVVETLICGVV 230


>gi|11527402 integral membrane protein 2B [Homo sapiens]
          Length = 266

 Score =  203 bits (517), Expect = 8e-53
 Identities = 98/185 (52%), Positives = 130/185 (70%), Gaps = 8/185 (4%)

Query: 41  LARDNFFRCGVLY--------EDSLSSQVRTQMELEEDVKIYLDENYERINVPVPQFGGG 92
           L  D+ + CG+ Y        E S  +       +EE++KI+ +E  E I+VPVP+F   
Sbjct: 81  LQPDDVYYCGIKYIKDDVILNEPSADAPAALYQTIEENIKIFEEEEVEFISVPVPEFADS 140

Query: 93  DPADIIHDFQRGLTAYHDISLDKCYVIELNTTIVLPPRNFWELLMNVKRGTYLPQTYIIQ 152
           DPA+I+HDF + LTAY D++LDKCYVI LNT+IV+PPRN  ELL+N+K GTYLPQ+Y+I 
Sbjct: 141 DPANIVHDFNKKLTAYLDLNLDKCYVIPLNTSIVMPPRNLLELLINIKAGTYLPQSYLIH 200

Query: 153 EEMVVTEHVSDKEALGSFIYHLCNGKDTYRLRRRATRRRINKRGAKNCNAIRHFENTFVV 212
           E MV+T+ + + + LG FIY LC+ K+TY+L+RR T + I KR A NC AIRHFEN F V
Sbjct: 201 EHMVITDRIENIDHLGFFIYRLCHDKETYKLQRRETIKGIQKREASNCFAIRHFENKFAV 260

Query: 213 ETLIC 217
           ETLIC
Sbjct: 261 ETLIC 265


>gi|4758224 integral membrane protein 2A [Homo sapiens]
          Length = 263

 Score =  159 bits (403), Expect = 1e-39
 Identities = 75/153 (49%), Positives = 100/153 (65%)

Query: 65  MELEEDVKIYLDENYERINVPVPQFGGGDPADIIHDFQRGLTAYHDISLDKCYVIELNTT 124
           + + E+  I  D+N   I+VPVP F   DPA IIHDF++G+TAY D+ L  CY++ LNT+
Sbjct: 109 LPVTEEADIREDDNIAIIDVPVPSFSDSDPAAIIHDFEKGMTAYLDLLLGNCYLMPLNTS 168

Query: 125 IVLPPRNFWELLMNVKRGTYLPQTYIIQEEMVVTEHVSDKEALGSFIYHLCNGKDTYRLR 184
           IV+PP+N  EL   +  G YLPQTY+++E++V  E + D   LG FIY LCN + ++RLR
Sbjct: 169 IVMPPKNLVELFGKLASGRYLPQTYVVREDLVAVEEIRDVSNLGIFIYQLCNNRKSFRLR 228

Query: 185 RRATRRRINKRGAKNCNAIRHFENTFVVETLIC 217
           RR      NKR    C  IRHF N F+VET IC
Sbjct: 229 RRDLLLGFNKRAIDKCWKIRHFPNEFIVETKIC 261


>gi|59806343 leukocyte cell derived chemotaxin 1 isoform 2 precursor
           [Homo sapiens]
          Length = 333

 Score = 29.3 bits (64), Expect = 2.8
 Identities = 28/117 (23%), Positives = 47/117 (40%), Gaps = 15/117 (12%)

Query: 91  GGDPADIIHDFQRGLTAYHDISLDKCYV-IELNTTIVLPPRNFWELLMNVKRGTYLPQTY 149
           G + A  ++DFQ G+T       +KCY+  ++   I        + + +   G  +P  Y
Sbjct: 106 GAEEAIAVNDFQNGITGIRFAGGEKCYIKAQVKARIPEVGAVTKQSISSKLEGKIMPVKY 165

Query: 150 IIQEE-----MVVTEHVSDKEALGSFIYHLCNG------KDTYRLRRRATRRRINKR 195
              EE     + V + V D   L S +  LC        K TY    +  RR + ++
Sbjct: 166 ---EENSLIWVAVDQPVKDNSFLSSKVLELCGDLPIFWLKPTYPKEIQRERREVVRK 219


>gi|5901932 leukocyte cell derived chemotaxin 1 isoform 1 precursor
           [Homo sapiens]
          Length = 334

 Score = 29.3 bits (64), Expect = 2.8
 Identities = 28/117 (23%), Positives = 47/117 (40%), Gaps = 15/117 (12%)

Query: 91  GGDPADIIHDFQRGLTAYHDISLDKCYV-IELNTTIVLPPRNFWELLMNVKRGTYLPQTY 149
           G + A  ++DFQ G+T       +KCY+  ++   I        + + +   G  +P  Y
Sbjct: 106 GAEEAIAVNDFQNGITGIRFAGGEKCYIKAQVKARIPEVGAVTKQSISSKLEGKIMPVKY 165

Query: 150 IIQEE-----MVVTEHVSDKEALGSFIYHLCNG------KDTYRLRRRATRRRINKR 195
              EE     + V + V D   L S +  LC        K TY    +  RR + ++
Sbjct: 166 ---EENSLIWVAVDQPVKDNSFLSSKVLELCGDLPIFWLKPTYPKEIQRERREVVRK 219


>gi|149773468 RAD51 associated protein 2 [Homo sapiens]
          Length = 1159

 Score = 28.9 bits (63), Expect = 3.6
 Identities = 19/63 (30%), Positives = 33/63 (52%), Gaps = 7/63 (11%)

Query: 96  DIIHDFQRGLTAYHDISLDKCYVIELNTTIVLPPRNFWELLMNVKRGTYLPQTYIIQEEM 155
           D+ +  Q+ + A H+I  ++    E +TT +    NFW LL  ++   Y     I++EE+
Sbjct: 785 DLCNVRQQAIPASHNIIHNE----ETHTTSITQVLNFWNLLSEIEEKKY---DLILKEEV 837

Query: 156 VVT 158
            VT
Sbjct: 838 KVT 840


>gi|156627559 tenomodulin [Homo sapiens]
          Length = 317

 Score = 28.1 bits (61), Expect = 6.1
 Identities = 10/28 (35%), Positives = 16/28 (57%)

Query: 91  GGDPADIIHDFQRGLTAYHDISLDKCYV 118
           G D    +HDF+ G T  + + L KC++
Sbjct: 95  GTDETLEVHDFKNGYTGIYFVGLQKCFI 122


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,300,500
Number of Sequences: 37866
Number of extensions: 366492
Number of successful extensions: 1071
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1062
Number of HSP's gapped (non-prelim): 12
length of query: 220
length of database: 18,247,518
effective HSP length: 98
effective length of query: 122
effective length of database: 14,536,650
effective search space: 1773471300
effective search space used: 1773471300
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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