Search of human proteins with 59710093

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|59710093 G-protein coupled receptor 112 [Homo sapiens]
         (3080 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|59710093 G-protein coupled receptor 112 [Homo sapiens]            6038   0.0  
gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens]   493   e-139
gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens]   493   e-139
gi|119943120 G protein-coupled receptor 64 isoform 1 [Homo sapiens]   493   e-139
gi|119943129 G protein-coupled receptor 64 isoform 4 [Homo sapiens]   493   e-139
gi|74048357 G protein-coupled receptor 126 alpha 1 precursor [Ho...   466   e-130
gi|50355941 G protein-coupled receptor 126 beta 1 precursor [Hom...   466   e-130
gi|74048422 G protein-coupled receptor 126 alpha 2 precursor [Ho...   465   e-130
gi|74048403 G protein-coupled receptor 126 beta 2 precursor [Hom...   465   e-130
gi|116284392 mucin 2 precursor [Homo sapiens]                         351   7e-96
gi|91982772 mucin 17 [Homo sapiens]                                   328   5e-89
gi|167736355 mucin 4 isoform a [Homo sapiens]                         260   2e-68
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                       229   4e-59
gi|224809323 G protein-coupled receptor 56 isoform b precursor [...   221   9e-57
gi|224809320 G protein-coupled receptor 56 isoform c precursor [...   221   9e-57
gi|224809318 G protein-coupled receptor 56 isoform b precursor [...   221   9e-57
gi|224809314 G protein-coupled receptor 56 isoform b precursor [...   221   9e-57
gi|41584198 G protein-coupled receptor 56 isoform b precursor [H...   221   9e-57
gi|41584202 G protein-coupled receptor 56 isoform b precursor [H...   221   9e-57
gi|41584200 G protein-coupled receptor 56 isoform a precursor [H...   214   8e-55
gi|224809316 G protein-coupled receptor 56 isoform a precursor [...   214   8e-55
gi|24475871 G protein-coupled receptor 114 [Homo sapiens]             213   2e-54
gi|83367077 mucin 16 [Homo sapiens]                                   211   9e-54
gi|6912464 latrophilin 2 precursor [Homo sapiens]                     210   2e-53
gi|163792198 latrophilin 3 precursor [Homo sapiens]                   204   8e-52
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]           203   2e-51
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]           201   9e-51
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ...   201   9e-51
gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]           201   9e-51
gi|229093087 G protein-coupled receptor 97 [Homo sapiens]             200   2e-50

>gi|59710093 G-protein coupled receptor 112 [Homo sapiens]
          Length = 3080

 Score = 6038 bits (15664), Expect = 0.0
 Identities = 3080/3080 (100%), Positives = 3080/3080 (100%)

Query: 1    MKEHIIYQKLYGLILMSSFIFLSDTLSLKGKKLDFFGRGDTYVSLIDTIPELSRFTACID 60
            MKEHIIYQKLYGLILMSSFIFLSDTLSLKGKKLDFFGRGDTYVSLIDTIPELSRFTACID
Sbjct: 1    MKEHIIYQKLYGLILMSSFIFLSDTLSLKGKKLDFFGRGDTYVSLIDTIPELSRFTACID 60

Query: 61   LVFMDDNSRYWMAFSYITNNALLGREDIDLGLAGDHQQLILYRLGKTFSIRHHLASFQWH 120
            LVFMDDNSRYWMAFSYITNNALLGREDIDLGLAGDHQQLILYRLGKTFSIRHHLASFQWH
Sbjct: 61   LVFMDDNSRYWMAFSYITNNALLGREDIDLGLAGDHQQLILYRLGKTFSIRHHLASFQWH 120

Query: 121  TICLIWDGVKGKLELFLNKERILEVTDQPHNLTPHGTLFLGHFLKNESSEVKSMMRSFPG 180
            TICLIWDGVKGKLELFLNKERILEVTDQPHNLTPHGTLFLGHFLKNESSEVKSMMRSFPG
Sbjct: 121  TICLIWDGVKGKLELFLNKERILEVTDQPHNLTPHGTLFLGHFLKNESSEVKSMMRSFPG 180

Query: 181  SLYYFQLWDHILENEEFMKCLDGNIVSWEEDVWLVNKIIPTVDRTLRCFVPENMTIQEKS 240
            SLYYFQLWDHILENEEFMKCLDGNIVSWEEDVWLVNKIIPTVDRTLRCFVPENMTIQEKS
Sbjct: 181  SLYYFQLWDHILENEEFMKCLDGNIVSWEEDVWLVNKIIPTVDRTLRCFVPENMTIQEKS 240

Query: 241  TTVSQQIDMTTPSQITGVKPQNTAHSSTLLSQSIPIFATDYTTISYSNTTSPPLETMTAQ 300
            TTVSQQIDMTTPSQITGVKPQNTAHSSTLLSQSIPIFATDYTTISYSNTTSPPLETMTAQ
Sbjct: 241  TTVSQQIDMTTPSQITGVKPQNTAHSSTLLSQSIPIFATDYTTISYSNTTSPPLETMTAQ 300

Query: 301  KILKTLVDETATFAVDVLSTSSAISLPTQSISIDNTTNSMKKTKSPSSESTKTTKMVEAM 360
            KILKTLVDETATFAVDVLSTSSAISLPTQSISIDNTTNSMKKTKSPSSESTKTTKMVEAM
Sbjct: 301  KILKTLVDETATFAVDVLSTSSAISLPTQSISIDNTTNSMKKTKSPSSESTKTTKMVEAM 360

Query: 361  ATEIFQPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFSTIESTSMSTTPCLKQ 420
            ATEIFQPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFSTIESTSMSTTPCLKQ
Sbjct: 361  ATEIFQPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFSTIESTSMSTTPCLKQ 420

Query: 421  KSTNTGALPISTAGQEFIESTAAGTVPWFTVEKTSPASTHVGTASSFPPEPVLISTAAPV 480
            KSTNTGALPISTAGQEFIESTAAGTVPWFTVEKTSPASTHVGTASSFPPEPVLISTAAPV
Sbjct: 421  KSTNTGALPISTAGQEFIESTAAGTVPWFTVEKTSPASTHVGTASSFPPEPVLISTAAPV 480

Query: 481  DSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETTPAPRTAETELTSTNFQDVSLPRV 540
            DSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETTPAPRTAETELTSTNFQDVSLPRV
Sbjct: 481  DSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETTPAPRTAETELTSTNFQDVSLPRV 540

Query: 541  EDAMSTSMSKETSSKTFSFLTSFSFTGTESVQTVIDAEATRTALTPEITLASTVAETMLS 600
            EDAMSTSMSKETSSKTFSFLTSFSFTGTESVQTVIDAEATRTALTPEITLASTVAETMLS
Sbjct: 541  EDAMSTSMSKETSSKTFSFLTSFSFTGTESVQTVIDAEATRTALTPEITLASTVAETMLS 600

Query: 601  STITGRVYTQNTPTADGHLLTLMSTRSASTSKAPESGPTSTTDEAAHLFSSNETIWTSRP 660
            STITGRVYTQNTPTADGHLLTLMSTRSASTSKAPESGPTSTTDEAAHLFSSNETIWTSRP
Sbjct: 601  STITGRVYTQNTPTADGHLLTLMSTRSASTSKAPESGPTSTTDEAAHLFSSNETIWTSRP 660

Query: 661  DQALLASMNTTTILTFVPNENFTSAFHENTTYTEYLSATTNITPLKASPEGKGTTANDAT 720
            DQALLASMNTTTILTFVPNENFTSAFHENTTYTEYLSATTNITPLKASPEGKGTTANDAT
Sbjct: 661  DQALLASMNTTTILTFVPNENFTSAFHENTTYTEYLSATTNITPLKASPEGKGTTANDAT 720

Query: 721  TARYTTAVSKLTSPWFANFSIVSGTTSITNMPEFKLTTLLLKTIPMSTKPANELPLTPRE 780
            TARYTTAVSKLTSPWFANFSIVSGTTSITNMPEFKLTTLLLKTIPMSTKPANELPLTPRE
Sbjct: 721  TARYTTAVSKLTSPWFANFSIVSGTTSITNMPEFKLTTLLLKTIPMSTKPANELPLTPRE 780

Query: 781  TVVPSVDIISTLACIQPNFSTEESASETTQTEINGAIVFGGTTTPVPKSATTQRLNATVT 840
            TVVPSVDIISTLACIQPNFSTEESASETTQTEINGAIVFGGTTTPVPKSATTQRLNATVT
Sbjct: 781  TVVPSVDIISTLACIQPNFSTEESASETTQTEINGAIVFGGTTTPVPKSATTQRLNATVT 840

Query: 841  RKEATSHYLMRKSTIAAVAEVSPFSTMLEVTDESAQRVTASVTVSSFPDIEKLSTPLDNK 900
            RKEATSHYLMRKSTIAAVAEVSPFSTMLEVTDESAQRVTASVTVSSFPDIEKLSTPLDNK
Sbjct: 841  RKEATSHYLMRKSTIAAVAEVSPFSTMLEVTDESAQRVTASVTVSSFPDIEKLSTPLDNK 900

Query: 901  TATTEVRESWLLTKLVKTTPRSSYNEMTEMFNFNHTYVAHWTSETSEGISAGSPTSGSTH 960
            TATTEVRESWLLTKLVKTTPRSSYNEMTEMFNFNHTYVAHWTSETSEGISAGSPTSGSTH
Sbjct: 901  TATTEVRESWLLTKLVKTTPRSSYNEMTEMFNFNHTYVAHWTSETSEGISAGSPTSGSTH 960

Query: 961  IFGEPLGASTTRISETSFSTTPTDRTATSLSDGILPPQPTAAHSSATPVPVTHMFSLPVN 1020
            IFGEPLGASTTRISETSFSTTPTDRTATSLSDGILPPQPTAAHSSATPVPVTHMFSLPVN
Sbjct: 961  IFGEPLGASTTRISETSFSTTPTDRTATSLSDGILPPQPTAAHSSATPVPVTHMFSLPVN 1020

Query: 1021 GSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVPPLDQTASTTIVIVPT 1080
            GSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVPPLDQTASTTIVIVPT
Sbjct: 1021 GSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVPPLDQTASTTIVIVPT 1080

Query: 1081 HGDLIRTTSEATVISVRKTSMAVPSLTETPFHSLRLSTPVTAKAETTLFSTSVDTVTPST 1140
            HGDLIRTTSEATVISVRKTSMAVPSLTETPFHSLRLSTPVTAKAETTLFSTSVDTVTPST
Sbjct: 1081 HGDLIRTTSEATVISVRKTSMAVPSLTETPFHSLRLSTPVTAKAETTLFSTSVDTVTPST 1140

Query: 1141 HTLVCSKPPPDNIPPASSTHVISTTSTPEATQPISQVEETSTYALSFPYTFSGGGVVASL 1200
            HTLVCSKPPPDNIPPASSTHVISTTSTPEATQPISQVEETSTYALSFPYTFSGGGVVASL
Sbjct: 1141 HTLVCSKPPPDNIPPASSTHVISTTSTPEATQPISQVEETSTYALSFPYTFSGGGVVASL 1200

Query: 1201 ATGTTETSVVDETTPSHISANKLTTSVNSHISSSATYRVHTPVSIQLVTSTSVLSSDKDQ 1260
            ATGTTETSVVDETTPSHISANKLTTSVNSHISSSATYRVHTPVSIQLVTSTSVLSSDKDQ
Sbjct: 1201 ATGTTETSVVDETTPSHISANKLTTSVNSHISSSATYRVHTPVSIQLVTSTSVLSSDKDQ 1260

Query: 1261 MTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSPSEIPL 1320
            MTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSPSEIPL
Sbjct: 1261 MTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSPSEIPL 1320

Query: 1321 GTPSDGNLASSPTSGSTQITPTLTSSNTVGVHIPEMSTSLGKTALPSQALTITTFLCPEK 1380
            GTPSDGNLASSPTSGSTQITPTLTSSNTVGVHIPEMSTSLGKTALPSQALTITTFLCPEK
Sbjct: 1321 GTPSDGNLASSPTSGSTQITPTLTSSNTVGVHIPEMSTSLGKTALPSQALTITTFLCPEK 1380

Query: 1381 ESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINTTFSHLH 1440
            ESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINTTFSHLH
Sbjct: 1381 ESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINTTFSHLH 1440

Query: 1441 SLRTQPEVTSVASFISESTQTFPESLSLSTAGLYNDGFTVLSDRITTAFSVPNVPTMLPR 1500
            SLRTQPEVTSVASFISESTQTFPESLSLSTAGLYNDGFTVLSDRITTAFSVPNVPTMLPR
Sbjct: 1441 SLRTQPEVTSVASFISESTQTFPESLSLSTAGLYNDGFTVLSDRITTAFSVPNVPTMLPR 1500

Query: 1501 ESSMATSTPIYQMSSLPVNVTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTATSGPMS 1560
            ESSMATSTPIYQMSSLPVNVTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTATSGPMS
Sbjct: 1501 ESSMATSTPIYQMSSLPVNVTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTATSGPMS 1560

Query: 1561 EMSSIPVNNSAFTPATVSSDTSTRVGLFSTLLSSVTPRTTMTMQTSTLDVTPVIYAGATS 1620
            EMSSIPVNNSAFTPATVSSDTSTRVGLFSTLLSSVTPRTTMTMQTSTLDVTPVIYAGATS
Sbjct: 1561 EMSSIPVNNSAFTPATVSSDTSTRVGLFSTLLSSVTPRTTMTMQTSTLDVTPVIYAGATS 1620

Query: 1621 KNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSPL 1680
            KNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSPL
Sbjct: 1621 KNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSPL 1680

Query: 1681 SSKSTGAISSIPKTTFSPFLSATQQSSQADEATTLGILSGITNRSLSTVNSGTGVALTDT 1740
            SSKSTGAISSIPKTTFSPFLSATQQSSQADEATTLGILSGITNRSLSTVNSGTGVALTDT
Sbjct: 1681 SSKSTGAISSIPKTTFSPFLSATQQSSQADEATTLGILSGITNRSLSTVNSGTGVALTDT 1740

Query: 1741 YSRITVPENMLSPTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTS 1800
            YSRITVPENMLSPTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTS
Sbjct: 1741 YSRITVPENMLSPTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTS 1800

Query: 1801 LLEKTSLTNYATSLNTPVSYPPWTPSSATLPSLTSFVYSPHSTEAEISTPKTSPPPTSQM 1860
            LLEKTSLTNYATSLNTPVSYPPWTPSSATLPSLTSFVYSPHSTEAEISTPKTSPPPTSQM
Sbjct: 1801 LLEKTSLTNYATSLNTPVSYPPWTPSSATLPSLTSFVYSPHSTEAEISTPKTSPPPTSQM 1860

Query: 1861 VEFPVLGTRMTSSNTQPLLMTSWNIPTAEGSQFPISTTINVPTSNEMETETLHLVPGPLS 1920
            VEFPVLGTRMTSSNTQPLLMTSWNIPTAEGSQFPISTTINVPTSNEMETETLHLVPGPLS
Sbjct: 1861 VEFPVLGTRMTSSNTQPLLMTSWNIPTAEGSQFPISTTINVPTSNEMETETLHLVPGPLS 1920

Query: 1921 TFTASQTGLVSKDVMAMSSIPMSGILPNHGLSENPSLSTSLRAITSTLADVKHTFEKMTT 1980
            TFTASQTGLVSKDVMAMSSIPMSGILPNHGLSENPSLSTSLRAITSTLADVKHTFEKMTT
Sbjct: 1921 TFTASQTGLVSKDVMAMSSIPMSGILPNHGLSENPSLSTSLRAITSTLADVKHTFEKMTT 1980

Query: 1981 SVTPGTTLPSILSGATSGSVISKSPILTWLLSSLPSGSPPATVSNAPHVMTSSTVEVSKS 2040
            SVTPGTTLPSILSGATSGSVISKSPILTWLLSSLPSGSPPATVSNAPHVMTSSTVEVSKS
Sbjct: 1981 SVTPGTTLPSILSGATSGSVISKSPILTWLLSSLPSGSPPATVSNAPHVMTSSTVEVSKS 2040

Query: 2041 TFLTSDMISAHPFTNLTTLPSATMSTILTRTIPTPTLGGITTGFPTSLPMSINVTDDIVY 2100
            TFLTSDMISAHPFTNLTTLPSATMSTILTRTIPTPTLGGITTGFPTSLPMSINVTDDIVY
Sbjct: 2041 TFLTSDMISAHPFTNLTTLPSATMSTILTRTIPTPTLGGITTGFPTSLPMSINVTDDIVY 2100

Query: 2101 ISTHPEASSRTTITANPRTVSHPSSFSRKTMSPSTTDHTLSVGAMPLPSSTITSSWNRIP 2160
            ISTHPEASSRTTITANPRTVSHPSSFSRKTMSPSTTDHTLSVGAMPLPSSTITSSWNRIP
Sbjct: 2101 ISTHPEASSRTTITANPRTVSHPSSFSRKTMSPSTTDHTLSVGAMPLPSSTITSSWNRIP 2160

Query: 2161 TASSPSTLIIPKPTLDSLLNIMTTTSTVPGASFPLISTGVTYPFTATVSSPISSFFETTW 2220
            TASSPSTLIIPKPTLDSLLNIMTTTSTVPGASFPLISTGVTYPFTATVSSPISSFFETTW
Sbjct: 2161 TASSPSTLIIPKPTLDSLLNIMTTTSTVPGASFPLISTGVTYPFTATVSSPISSFFETTW 2220

Query: 2221 LDSTPSFLSTEASTSPTATKSTVSFYNVEMSFSVFVEEPRIPITSVINEFTENSLNSIFQ 2280
            LDSTPSFLSTEASTSPTATKSTVSFYNVEMSFSVFVEEPRIPITSVINEFTENSLNSIFQ
Sbjct: 2221 LDSTPSFLSTEASTSPTATKSTVSFYNVEMSFSVFVEEPRIPITSVINEFTENSLNSIFQ 2280

Query: 2281 NSEFSLATLETQIKSRDISEEEMVMDRAILEQREGQEMATISYVPYSCVCQVIIKASSSL 2340
            NSEFSLATLETQIKSRDISEEEMVMDRAILEQREGQEMATISYVPYSCVCQVIIKASSSL
Sbjct: 2281 NSEFSLATLETQIKSRDISEEEMVMDRAILEQREGQEMATISYVPYSCVCQVIIKASSSL 2340

Query: 2341 ASSELMRKIKSKIHGNFTHGNFTQDQLTLLVNCEHVAVKKLEPGNCKADETASKYKGTYK 2400
            ASSELMRKIKSKIHGNFTHGNFTQDQLTLLVNCEHVAVKKLEPGNCKADETASKYKGTYK
Sbjct: 2341 ASSELMRKIKSKIHGNFTHGNFTQDQLTLLVNCEHVAVKKLEPGNCKADETASKYKGTYK 2400

Query: 2401 WLLTNPTETAQTRCIKNEDGNATRFCSISINTGKSQWEKPKFKQCKLLQELPDKIVDLAN 2460
            WLLTNPTETAQTRCIKNEDGNATRFCSISINTGKSQWEKPKFKQCKLLQELPDKIVDLAN
Sbjct: 2401 WLLTNPTETAQTRCIKNEDGNATRFCSISINTGKSQWEKPKFKQCKLLQELPDKIVDLAN 2460

Query: 2461 ITISDENAEDVAEHILNLINESPALGKEETKIIVSKISDISQCDEISMNLTHVMLQIINV 2520
            ITISDENAEDVAEHILNLINESPALGKEETKIIVSKISDISQCDEISMNLTHVMLQIINV
Sbjct: 2461 ITISDENAEDVAEHILNLINESPALGKEETKIIVSKISDISQCDEISMNLTHVMLQIINV 2520

Query: 2521 VLEKQNNSASDLHEISNEILRIIERTGHKMEFSGQIANLTVAGLALAVLRGDHTFDGMAF 2580
            VLEKQNNSASDLHEISNEILRIIERTGHKMEFSGQIANLTVAGLALAVLRGDHTFDGMAF
Sbjct: 2521 VLEKQNNSASDLHEISNEILRIIERTGHKMEFSGQIANLTVAGLALAVLRGDHTFDGMAF 2580

Query: 2581 SIHSYEEGTDPEIFLGNVPVGGILASIYLPKSLTERIPLSNLQTILFNFFGQTSLFKTKN 2640
            SIHSYEEGTDPEIFLGNVPVGGILASIYLPKSLTERIPLSNLQTILFNFFGQTSLFKTKN
Sbjct: 2581 SIHSYEEGTDPEIFLGNVPVGGILASIYLPKSLTERIPLSNLQTILFNFFGQTSLFKTKN 2640

Query: 2641 VTKALTTYVVSASISDDMFIQNLADPVVITLQHIGGNQNYGQVHCAFWDFENNNGLGGWN 2700
            VTKALTTYVVSASISDDMFIQNLADPVVITLQHIGGNQNYGQVHCAFWDFENNNGLGGWN
Sbjct: 2641 VTKALTTYVVSASISDDMFIQNLADPVVITLQHIGGNQNYGQVHCAFWDFENNNGLGGWN 2700

Query: 2701 SSGCKVKETNVNYTICQCDHLTHFGVLMDLSRSTVDSVNEQILALITYTGCGISSIFLGV 2760
            SSGCKVKETNVNYTICQCDHLTHFGVLMDLSRSTVDSVNEQILALITYTGCGISSIFLGV
Sbjct: 2701 SSGCKVKETNVNYTICQCDHLTHFGVLMDLSRSTVDSVNEQILALITYTGCGISSIFLGV 2760

Query: 2761 AVVTYIAFHKLRKDYPAKILINLCTALLMLNLVFLINSWLSSFQKVGVCITAAVALHYFL 2820
            AVVTYIAFHKLRKDYPAKILINLCTALLMLNLVFLINSWLSSFQKVGVCITAAVALHYFL
Sbjct: 2761 AVVTYIAFHKLRKDYPAKILINLCTALLMLNLVFLINSWLSSFQKVGVCITAAVALHYFL 2820

Query: 2821 LVSFTWMGLEAVHMYLALVKVFNIYIPNYILKFCLVGWGIPAIMVAITVSVKKDLYGTLS 2880
            LVSFTWMGLEAVHMYLALVKVFNIYIPNYILKFCLVGWGIPAIMVAITVSVKKDLYGTLS
Sbjct: 2821 LVSFTWMGLEAVHMYLALVKVFNIYIPNYILKFCLVGWGIPAIMVAITVSVKKDLYGTLS 2880

Query: 2881 PTTPFCWIKDDSIFYISVVAYFCLIFLMNLSMFCTVLVQLNSVKSQIQKTRRKMILHDLK 2940
            PTTPFCWIKDDSIFYISVVAYFCLIFLMNLSMFCTVLVQLNSVKSQIQKTRRKMILHDLK
Sbjct: 2881 PTTPFCWIKDDSIFYISVVAYFCLIFLMNLSMFCTVLVQLNSVKSQIQKTRRKMILHDLK 2940

Query: 2941 GTMSLTFLLGLTWGFAFFAWGPMRNFFLYLFAIFNTLQGFFIFVFHCVMKESVREQWQIH 3000
            GTMSLTFLLGLTWGFAFFAWGPMRNFFLYLFAIFNTLQGFFIFVFHCVMKESVREQWQIH
Sbjct: 2941 GTMSLTFLLGLTWGFAFFAWGPMRNFFLYLFAIFNTLQGFFIFVFHCVMKESVREQWQIH 3000

Query: 3001 LCCGWLRLDNSSDGSSRCQIKVGYKQEGLKKIFEHKLLTPSLKSTATSSTFKSLGSAQGT 3060
            LCCGWLRLDNSSDGSSRCQIKVGYKQEGLKKIFEHKLLTPSLKSTATSSTFKSLGSAQGT
Sbjct: 3001 LCCGWLRLDNSSDGSSRCQIKVGYKQEGLKKIFEHKLLTPSLKSTATSSTFKSLGSAQGT 3060

Query: 3061 PSEISFPNDDFDKDPYCSSP 3080
            PSEISFPNDDFDKDPYCSSP
Sbjct: 3061 PSEISFPNDDFDKDPYCSSP 3080


>gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens]
          Length = 995

 Score =  493 bits (1270), Expect = e-139
 Identities = 257/548 (46%), Positives = 363/548 (66%), Gaps = 26/548 (4%)

Query: 2516 QIINVVLEKQNNSASDLHEISNEILRIIERTGHKMEFSGQIANLTVAGLALAVLRGDHTF 2575
            ++IN V    ++    L  ++  +L++++  G ++ FS    +LT   LALAV+R     
Sbjct: 378  EMINQVSRLLHSPPDMLAPLAQRLLKVVDDIGLQLNFSNTTISLTSPSLALAVIR----V 433

Query: 2576 DGMAFSIHSY--EEGTDPEIFLGNVPVGGILASIYLPKSLTERIPLSNLQT---ILFNFF 2630
            +  +F+  ++  ++  + ++ L        + +I LP SL   +P  +++    + FNFF
Sbjct: 434  NASSFNTTTFVAQDPANLQVSLETQAPENSIGTITLPSSLMNNLPAHDMELASRVQFNFF 493

Query: 2631 GQTSLFKTKNVTK-ALTTYVVSASISDDMFIQNLADPVVITLQHIGGNQNYGQVHCAFWD 2689
               +LF+  ++   +L +YV+S+S+++ + ++NL   V +TL+HI  +Q+   V C FWD
Sbjct: 494  ETPALFQDPSLENLSLISYVISSSVAN-LTVRNLTRNVTVTLKHINPSQDELTVRCVFWD 552

Query: 2690 FENNNGLGGWNSSGCKVKETNVNYTICQCDHLTHFGVLMDLSRSTVDSVNEQILALITYT 2749
               N G GGW+ +GC VK+  +N TIC C HLT FGVL+DLSR++V       L  ITY 
Sbjct: 553  LGRNGGRGGWSDNGCSVKDRRLNETICTCSHLTSFGVLLDLSRTSVLPAQMMALTFITYI 612

Query: 2750 GCGISSIFLGVAVVTYIAFHKLRKDYPAKILINLCTALLMLNLVFLINSWLSSFQKVGVC 2809
            GCG+SSIFL V +VTYIAF K+R+DYP+KILI LC ALL+LNLVFL++SW++ ++  G+C
Sbjct: 613  GCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYKMQGLC 672

Query: 2810 ITAAVALHYFLLVSFTWMGLEAVHMYLALVKVFNIYIPNYILKFCLVGWGIPAIMVAITV 2869
            I+ AV LHYFLLVSFTWMGLEA HMYLALVKVFN YI  YILKFC+VGWG+PA++V I +
Sbjct: 673  ISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFCIVGWGVPAVVVTIIL 732

Query: 2870 SVKKDLYGTLS-------PTTPFCWIKDDSIFYISVVAYFCLIFLMNLSMFCTVLVQLNS 2922
            ++  D YG  S           FCWI ++++FYI+VV YFC+IFL+N+SMF  VLVQL  
Sbjct: 733  TISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFLLNVSMFIVVLVQLCR 792

Query: 2923 VKSQIQ-KTRRKMILHDLKGTMSLTFLLGLTWGFAFFAWGPMRNFFLYLFAIFNTLQGFF 2981
            +K + Q   +RK  + DL+    LTFLLG+TWGFAFFAWGP+   F+YLFAIFNTLQGFF
Sbjct: 793  IKKKKQLGAQRKTSIQDLRSIAGLTFLLGITWGFAFFAWGPVNVTFMYLFAIFNTLQGFF 852

Query: 2982 IFVFHCVMKESVREQWQIHLCCGWLRLDNSSDGSSRCQIKVGYKQEGLKKIFEHKLLTPS 3041
            IF+F+CV KE+VR+QW+ +LCCG LRL  +SD S            GLKK   ++ ++ S
Sbjct: 853  IFIFYCVAKENVRKQWRRYLCCGKLRLAENSDWSKTA-------TNGLKKQTVNQGVSSS 905

Query: 3042 LKSTATSS 3049
              S  +SS
Sbjct: 906  SNSLQSSS 913



 Score = 33.5 bits (75), Expect = 3.3
 Identities = 30/114 (26%), Positives = 51/114 (44%), Gaps = 15/114 (13%)

Query: 1811 ATSLNTPVSYPPWTPSSATLPSLTSFVY--SPHSTEAEISTPKTSPPPTSQMVEFPVLGT 1868
            ATS   P   P ++P +  +PS    +   SP  +    S+P    PP S+ +  P+  T
Sbjct: 254  ATSFAEP---PDYSPVTHNVPSPIGEIQPLSPQPSAPIASSPAIDMPPQSETISSPMPQT 310

Query: 1869 RMTSSNTQPLLMTSWNIPTAEG-------SQFPISTTI-NVPTSNEMETETLHL 1914
             +  S T P +  S++ PT          S  P+ T I N  + +++E + L +
Sbjct: 311  HV--SGTPPPVKASFSSPTVSAPANVNTTSAPPVQTDIVNTSSISDLENQVLQM 362


>gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens]
          Length = 1003

 Score =  493 bits (1270), Expect = e-139
 Identities = 257/548 (46%), Positives = 363/548 (66%), Gaps = 26/548 (4%)

Query: 2516 QIINVVLEKQNNSASDLHEISNEILRIIERTGHKMEFSGQIANLTVAGLALAVLRGDHTF 2575
            ++IN V    ++    L  ++  +L++++  G ++ FS    +LT   LALAV+R     
Sbjct: 386  EMINQVSRLLHSPPDMLAPLAQRLLKVVDDIGLQLNFSNTTISLTSPSLALAVIR----V 441

Query: 2576 DGMAFSIHSY--EEGTDPEIFLGNVPVGGILASIYLPKSLTERIPLSNLQT---ILFNFF 2630
            +  +F+  ++  ++  + ++ L        + +I LP SL   +P  +++    + FNFF
Sbjct: 442  NASSFNTTTFVAQDPANLQVSLETQAPENSIGTITLPSSLMNNLPAHDMELASRVQFNFF 501

Query: 2631 GQTSLFKTKNVTK-ALTTYVVSASISDDMFIQNLADPVVITLQHIGGNQNYGQVHCAFWD 2689
               +LF+  ++   +L +YV+S+S+++ + ++NL   V +TL+HI  +Q+   V C FWD
Sbjct: 502  ETPALFQDPSLENLSLISYVISSSVAN-LTVRNLTRNVTVTLKHINPSQDELTVRCVFWD 560

Query: 2690 FENNNGLGGWNSSGCKVKETNVNYTICQCDHLTHFGVLMDLSRSTVDSVNEQILALITYT 2749
               N G GGW+ +GC VK+  +N TIC C HLT FGVL+DLSR++V       L  ITY 
Sbjct: 561  LGRNGGRGGWSDNGCSVKDRRLNETICTCSHLTSFGVLLDLSRTSVLPAQMMALTFITYI 620

Query: 2750 GCGISSIFLGVAVVTYIAFHKLRKDYPAKILINLCTALLMLNLVFLINSWLSSFQKVGVC 2809
            GCG+SSIFL V +VTYIAF K+R+DYP+KILI LC ALL+LNLVFL++SW++ ++  G+C
Sbjct: 621  GCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYKMQGLC 680

Query: 2810 ITAAVALHYFLLVSFTWMGLEAVHMYLALVKVFNIYIPNYILKFCLVGWGIPAIMVAITV 2869
            I+ AV LHYFLLVSFTWMGLEA HMYLALVKVFN YI  YILKFC+VGWG+PA++V I +
Sbjct: 681  ISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFCIVGWGVPAVVVTIIL 740

Query: 2870 SVKKDLYGTLS-------PTTPFCWIKDDSIFYISVVAYFCLIFLMNLSMFCTVLVQLNS 2922
            ++  D YG  S           FCWI ++++FYI+VV YFC+IFL+N+SMF  VLVQL  
Sbjct: 741  TISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFLLNVSMFIVVLVQLCR 800

Query: 2923 VKSQIQ-KTRRKMILHDLKGTMSLTFLLGLTWGFAFFAWGPMRNFFLYLFAIFNTLQGFF 2981
            +K + Q   +RK  + DL+    LTFLLG+TWGFAFFAWGP+   F+YLFAIFNTLQGFF
Sbjct: 801  IKKKKQLGAQRKTSIQDLRSIAGLTFLLGITWGFAFFAWGPVNVTFMYLFAIFNTLQGFF 860

Query: 2982 IFVFHCVMKESVREQWQIHLCCGWLRLDNSSDGSSRCQIKVGYKQEGLKKIFEHKLLTPS 3041
            IF+F+CV KE+VR+QW+ +LCCG LRL  +SD S            GLKK   ++ ++ S
Sbjct: 861  IFIFYCVAKENVRKQWRRYLCCGKLRLAENSDWSKTA-------TNGLKKQTVNQGVSSS 913

Query: 3042 LKSTATSS 3049
              S  +SS
Sbjct: 914  SNSLQSSS 921



 Score = 33.5 bits (75), Expect = 3.3
 Identities = 80/366 (21%), Positives = 136/366 (37%), Gaps = 42/366 (11%)

Query: 205 IVSWEEDVWLVNKIIPTVDRTLRCFVPENMTIQEKSTTVSQQIDMTT-PSQITGVKPQ-N 262
           + S EED    +   P    ++  F P +    E  TT    + ++  PS  TGVKPQ N
Sbjct: 35  VTSLEEDTDNSSLSPPPAKLSVVSFAPSSNGTPEVETTSLNDVTLSLLPSNETGVKPQRN 94

Query: 263 TAHSSTLLSQSIPIFATDYTTISYSNTTSPP---------------LETMTAQKILKTLV 307
             + S++ + S   F        Y   ++ P               L  +   ++ KTL 
Sbjct: 95  ICNLSSICNDS--AFFRGEIMFQYDKESTVPQNQHITNGTLTGVLSLSELKRSELNKTLQ 152

Query: 308 DETATFAVDVLSTSSAISLP-TQSISIDNTTNSMKKTKSPSSESTKTTKMVE-AMATEIF 365
             + T+ +   +  +  +L  T +I ++NT N+       + E  K   M     +  I 
Sbjct: 153 TLSETYFIMCATAEAQSTLNCTFTIKLNNTMNAC--AVIAALERVKIRPMEHCCCSVRIP 210

Query: 366 QPPTPSNFLSTSRFTKNSVVSTT--------SAIKSQSAVTKTTSLFSTIESTSMSTTPC 417
            P +P          ++ +V           S+ +S   V + T L    ++TS +  P 
Sbjct: 211 CPSSPEELEKLQCDLQDPIVCLADHPRGPPFSSSQSIPVVPRATVLSQVPKATSFAEPPD 270

Query: 418 LKQKSTNTGA-----LPISTAGQEFIESTAAGTVPWFTVEKTSP-ASTHVGTASSFPPEP 471
               + N  +      P+S      I S+ A  +P  +   +SP   THV    S  P P
Sbjct: 271 YSPVTHNVPSPIGEIQPLSPQPSAPIASSPAIDMPPQSETISSPMPQTHV----SGTPPP 326

Query: 472 VLISTAAP-VDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETTPAPRTAETELTST 530
           V  S ++P V +    N T+ P   TD+    ++  L      +E   +  + E  L   
Sbjct: 327 VKASFSSPTVSAPANVNTTSAPPVQTDIVNTSSISDLENQVLQMEKALSLGSLEPNLAGE 386

Query: 531 NFQDVS 536
               VS
Sbjct: 387 MINQVS 392



 Score = 33.5 bits (75), Expect = 3.3
 Identities = 30/114 (26%), Positives = 51/114 (44%), Gaps = 15/114 (13%)

Query: 1811 ATSLNTPVSYPPWTPSSATLPSLTSFVY--SPHSTEAEISTPKTSPPPTSQMVEFPVLGT 1868
            ATS   P   P ++P +  +PS    +   SP  +    S+P    PP S+ +  P+  T
Sbjct: 262  ATSFAEP---PDYSPVTHNVPSPIGEIQPLSPQPSAPIASSPAIDMPPQSETISSPMPQT 318

Query: 1869 RMTSSNTQPLLMTSWNIPTAEG-------SQFPISTTI-NVPTSNEMETETLHL 1914
             +  S T P +  S++ PT          S  P+ T I N  + +++E + L +
Sbjct: 319  HV--SGTPPPVKASFSSPTVSAPANVNTTSAPPVQTDIVNTSSISDLENQVLQM 370


>gi|119943120 G protein-coupled receptor 64 isoform 1 [Homo sapiens]
          Length = 1017

 Score =  493 bits (1270), Expect = e-139
 Identities = 257/548 (46%), Positives = 363/548 (66%), Gaps = 26/548 (4%)

Query: 2516 QIINVVLEKQNNSASDLHEISNEILRIIERTGHKMEFSGQIANLTVAGLALAVLRGDHTF 2575
            ++IN V    ++    L  ++  +L++++  G ++ FS    +LT   LALAV+R     
Sbjct: 400  EMINQVSRLLHSPPDMLAPLAQRLLKVVDDIGLQLNFSNTTISLTSPSLALAVIR----V 455

Query: 2576 DGMAFSIHSY--EEGTDPEIFLGNVPVGGILASIYLPKSLTERIPLSNLQT---ILFNFF 2630
            +  +F+  ++  ++  + ++ L        + +I LP SL   +P  +++    + FNFF
Sbjct: 456  NASSFNTTTFVAQDPANLQVSLETQAPENSIGTITLPSSLMNNLPAHDMELASRVQFNFF 515

Query: 2631 GQTSLFKTKNVTK-ALTTYVVSASISDDMFIQNLADPVVITLQHIGGNQNYGQVHCAFWD 2689
               +LF+  ++   +L +YV+S+S+++ + ++NL   V +TL+HI  +Q+   V C FWD
Sbjct: 516  ETPALFQDPSLENLSLISYVISSSVAN-LTVRNLTRNVTVTLKHINPSQDELTVRCVFWD 574

Query: 2690 FENNNGLGGWNSSGCKVKETNVNYTICQCDHLTHFGVLMDLSRSTVDSVNEQILALITYT 2749
               N G GGW+ +GC VK+  +N TIC C HLT FGVL+DLSR++V       L  ITY 
Sbjct: 575  LGRNGGRGGWSDNGCSVKDRRLNETICTCSHLTSFGVLLDLSRTSVLPAQMMALTFITYI 634

Query: 2750 GCGISSIFLGVAVVTYIAFHKLRKDYPAKILINLCTALLMLNLVFLINSWLSSFQKVGVC 2809
            GCG+SSIFL V +VTYIAF K+R+DYP+KILI LC ALL+LNLVFL++SW++ ++  G+C
Sbjct: 635  GCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYKMQGLC 694

Query: 2810 ITAAVALHYFLLVSFTWMGLEAVHMYLALVKVFNIYIPNYILKFCLVGWGIPAIMVAITV 2869
            I+ AV LHYFLLVSFTWMGLEA HMYLALVKVFN YI  YILKFC+VGWG+PA++V I +
Sbjct: 695  ISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFCIVGWGVPAVVVTIIL 754

Query: 2870 SVKKDLYGTLS-------PTTPFCWIKDDSIFYISVVAYFCLIFLMNLSMFCTVLVQLNS 2922
            ++  D YG  S           FCWI ++++FYI+VV YFC+IFL+N+SMF  VLVQL  
Sbjct: 755  TISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFLLNVSMFIVVLVQLCR 814

Query: 2923 VKSQIQ-KTRRKMILHDLKGTMSLTFLLGLTWGFAFFAWGPMRNFFLYLFAIFNTLQGFF 2981
            +K + Q   +RK  + DL+    LTFLLG+TWGFAFFAWGP+   F+YLFAIFNTLQGFF
Sbjct: 815  IKKKKQLGAQRKTSIQDLRSIAGLTFLLGITWGFAFFAWGPVNVTFMYLFAIFNTLQGFF 874

Query: 2982 IFVFHCVMKESVREQWQIHLCCGWLRLDNSSDGSSRCQIKVGYKQEGLKKIFEHKLLTPS 3041
            IF+F+CV KE+VR+QW+ +LCCG LRL  +SD S            GLKK   ++ ++ S
Sbjct: 875  IFIFYCVAKENVRKQWRRYLCCGKLRLAENSDWSKTA-------TNGLKKQTVNQGVSSS 927

Query: 3042 LKSTATSS 3049
              S  +SS
Sbjct: 928  SNSLQSSS 935



 Score = 33.5 bits (75), Expect = 3.3
 Identities = 30/114 (26%), Positives = 51/114 (44%), Gaps = 15/114 (13%)

Query: 1811 ATSLNTPVSYPPWTPSSATLPSLTSFVY--SPHSTEAEISTPKTSPPPTSQMVEFPVLGT 1868
            ATS   P   P ++P +  +PS    +   SP  +    S+P    PP S+ +  P+  T
Sbjct: 276  ATSFAEP---PDYSPVTHNVPSPIGEIQPLSPQPSAPIASSPAIDMPPQSETISSPMPQT 332

Query: 1869 RMTSSNTQPLLMTSWNIPTAEG-------SQFPISTTI-NVPTSNEMETETLHL 1914
             +  S T P +  S++ PT          S  P+ T I N  + +++E + L +
Sbjct: 333  HV--SGTPPPVKASFSSPTVSAPANVNTTSAPPVQTDIVNTSSISDLENQVLQM 384


>gi|119943129 G protein-coupled receptor 64 isoform 4 [Homo sapiens]
          Length = 1014

 Score =  493 bits (1270), Expect = e-139
 Identities = 257/548 (46%), Positives = 363/548 (66%), Gaps = 26/548 (4%)

Query: 2516 QIINVVLEKQNNSASDLHEISNEILRIIERTGHKMEFSGQIANLTVAGLALAVLRGDHTF 2575
            ++IN V    ++    L  ++  +L++++  G ++ FS    +LT   LALAV+R     
Sbjct: 397  EMINQVSRLLHSPPDMLAPLAQRLLKVVDDIGLQLNFSNTTISLTSPSLALAVIR----V 452

Query: 2576 DGMAFSIHSY--EEGTDPEIFLGNVPVGGILASIYLPKSLTERIPLSNLQT---ILFNFF 2630
            +  +F+  ++  ++  + ++ L        + +I LP SL   +P  +++    + FNFF
Sbjct: 453  NASSFNTTTFVAQDPANLQVSLETQAPENSIGTITLPSSLMNNLPAHDMELASRVQFNFF 512

Query: 2631 GQTSLFKTKNVTK-ALTTYVVSASISDDMFIQNLADPVVITLQHIGGNQNYGQVHCAFWD 2689
               +LF+  ++   +L +YV+S+S+++ + ++NL   V +TL+HI  +Q+   V C FWD
Sbjct: 513  ETPALFQDPSLENLSLISYVISSSVAN-LTVRNLTRNVTVTLKHINPSQDELTVRCVFWD 571

Query: 2690 FENNNGLGGWNSSGCKVKETNVNYTICQCDHLTHFGVLMDLSRSTVDSVNEQILALITYT 2749
               N G GGW+ +GC VK+  +N TIC C HLT FGVL+DLSR++V       L  ITY 
Sbjct: 572  LGRNGGRGGWSDNGCSVKDRRLNETICTCSHLTSFGVLLDLSRTSVLPAQMMALTFITYI 631

Query: 2750 GCGISSIFLGVAVVTYIAFHKLRKDYPAKILINLCTALLMLNLVFLINSWLSSFQKVGVC 2809
            GCG+SSIFL V +VTYIAF K+R+DYP+KILI LC ALL+LNLVFL++SW++ ++  G+C
Sbjct: 632  GCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFLLDSWIALYKMQGLC 691

Query: 2810 ITAAVALHYFLLVSFTWMGLEAVHMYLALVKVFNIYIPNYILKFCLVGWGIPAIMVAITV 2869
            I+ AV LHYFLLVSFTWMGLEA HMYLALVKVFN YI  YILKFC+VGWG+PA++V I +
Sbjct: 692  ISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFCIVGWGVPAVVVTIIL 751

Query: 2870 SVKKDLYGTLS-------PTTPFCWIKDDSIFYISVVAYFCLIFLMNLSMFCTVLVQLNS 2922
            ++  D YG  S           FCWI ++++FYI+VV YFC+IFL+N+SMF  VLVQL  
Sbjct: 752  TISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFLLNVSMFIVVLVQLCR 811

Query: 2923 VKSQIQ-KTRRKMILHDLKGTMSLTFLLGLTWGFAFFAWGPMRNFFLYLFAIFNTLQGFF 2981
            +K + Q   +RK  + DL+    LTFLLG+TWGFAFFAWGP+   F+YLFAIFNTLQGFF
Sbjct: 812  IKKKKQLGAQRKTSIQDLRSIAGLTFLLGITWGFAFFAWGPVNVTFMYLFAIFNTLQGFF 871

Query: 2982 IFVFHCVMKESVREQWQIHLCCGWLRLDNSSDGSSRCQIKVGYKQEGLKKIFEHKLLTPS 3041
            IF+F+CV KE+VR+QW+ +LCCG LRL  +SD S            GLKK   ++ ++ S
Sbjct: 872  IFIFYCVAKENVRKQWRRYLCCGKLRLAENSDWSKTA-------TNGLKKQTVNQGVSSS 924

Query: 3042 LKSTATSS 3049
              S  +SS
Sbjct: 925  SNSLQSSS 932



 Score = 33.5 bits (75), Expect = 3.3
 Identities = 30/114 (26%), Positives = 51/114 (44%), Gaps = 15/114 (13%)

Query: 1811 ATSLNTPVSYPPWTPSSATLPSLTSFVY--SPHSTEAEISTPKTSPPPTSQMVEFPVLGT 1868
            ATS   P   P ++P +  +PS    +   SP  +    S+P    PP S+ +  P+  T
Sbjct: 273  ATSFAEP---PDYSPVTHNVPSPIGEIQPLSPQPSAPIASSPAIDMPPQSETISSPMPQT 329

Query: 1869 RMTSSNTQPLLMTSWNIPTAEG-------SQFPISTTI-NVPTSNEMETETLHL 1914
             +  S T P +  S++ PT          S  P+ T I N  + +++E + L +
Sbjct: 330  HV--SGTPPPVKASFSSPTVSAPANVNTTSAPPVQTDIVNTSSISDLENQVLQM 381


>gi|74048357 G protein-coupled receptor 126 alpha 1 precursor [Homo
            sapiens]
          Length = 1221

 Score =  466 bits (1198), Expect = e-130
 Identities = 313/877 (35%), Positives = 474/877 (54%), Gaps = 100/877 (11%)

Query: 2206 ATVSSPISSFFETTWLDSTPSFLSTEASTSPTATKSTVS--FYNVEMSFSVFVEEPRIPI 2263
            ATV+SP           +TP  ++T    +    K       Y + +     +  P + +
Sbjct: 380  ATVNSP----------STTPPTVTTNMPVTNRIDKQRNDGIIYRISVVIQNILRHPEVKV 429

Query: 2264 TSVINEFTENSLNSIFQNSEFSLATLETQIKSRDISEEEMVMDRAILEQREGQEMATISY 2323
             S + E+    LNS FQN  +++  +          E+++ + R++ ++      A + Y
Sbjct: 430  QSKVAEW----LNSTFQNWNYTVYVVNISFHL-SAGEDKIKVKRSLEDEPRLVLWALLVY 484

Query: 2324 VPYSCVCQVIIKASSSLASSELMRKIKSKIHGNFTHGNFTQDQLTLLVNCEHVAVKKLEP 2383
                          ++  ++ L  KI   I       N + D+   L     V V++L  
Sbjct: 485  --------------NATNNTNLEGKI---IQQKLLKNNESLDEGLRL---HTVNVRQL-- 522

Query: 2384 GNCKADETASKYKGTYKWLLTNPTETAQTRCIKNEDGNATRFCSISINTGKSQWEKPKFK 2443
            G+C A E     KG Y W    P+E     C      +A+R C  +       +  P   
Sbjct: 523  GHCLAMEEP---KGYY-WPSIQPSEYVLP-CPDKPGFSASRICFYNATNPLVTYWGP--- 574

Query: 2444 QCKLLQELPDKIVDLANITISDENAEDVAEHILNLINESPALGKEETKIIVSKISDISQC 2503
                        VD++N     + A +VA  ILNL  +   L       IV ++  I   
Sbjct: 575  ------------VDISNCL---KEANEVANQILNLTADGQNLTSANITNIVEQVKRIVNK 619

Query: 2504 DE-ISMNLTHVMLQIINVVLEKQNNSASDLHEISNEILRIIERTGHKMEF-SGQIANLTV 2561
            +E I + L   ++ I + +L   ++S SDL E S+E L+ I+    K++  S    N+T 
Sbjct: 620  EENIDITLGSTLMNIFSNIL---SSSDSDLLESSSEALKTIDELAFKIDLNSTSHVNITT 676

Query: 2562 AGLALAV---LRGDHTFDGMAFSIHSYEEGTDPEIFLGNVPVGGI--LASIYLPKSLTER 2616
              LAL+V   L G +     +  + S  E      F  +   G +  LAS+ LP +L E 
Sbjct: 677  RNLALSVSSLLPGTNAISNFSIGLPSNNES----YFQMDFESGQVDPLASVILPPNLLEN 732

Query: 2617 IPLSN---LQTILFNFFGQTSLFKTKNVT-KALTTYVVSASISDDMFIQNLADPVVITLQ 2672
            +   +   ++   F FF +T LF+      K L +YV++ SI + + IQNL DPV I ++
Sbjct: 733  LSPEDSVLVRRAQFTFFNKTGLFQDVGPQRKTLVSYVMACSIGN-ITIQNLKDPVQIKIK 791

Query: 2673 HIGGNQNYGQVHCAFWDFENNNGLGGWNSSGCKV-KETNVNYTICQCDHLTHFGVLMDLS 2731
            H    + +  + CAFWD   N   GGWN+SGC   ++++ + T+C C+H THFGVLMDL 
Sbjct: 792  HTRTQEVHHPI-CAFWDLNKNKSFGGWNTSGCVAHRDSDASETVCLCNHFTHFGVLMDLP 850

Query: 2732 RST--VDSVNEQILALITYTGCGISSIFLGVAVVTYIAFHKLRKDYPAKILINLCTALLM 2789
            RS   +D+ N ++L  I+Y GCGIS+IF    ++TY+AF KLR+DYP+KIL+NL TALL 
Sbjct: 851  RSASQLDARNTKVLTFISYIGCGISAIFSAATLLTYVAFEKLRRDYPSKILMNLSTALLF 910

Query: 2790 LNLVFLINSWLSSFQKVGVCITAAVALHYFLLVSFTWMGLEAVHMYLALVKVFNIYIPNY 2849
            LNL+FL++ W++SF   G+CI  AV LH+FLL +FTWMGLEA+HMY+ALVKVFN YI  Y
Sbjct: 911  LNLLFLLDGWITSFNVDGLCIAVAVLLHFFLLATFTWMGLEAIHMYIALVKVFNTYIRRY 970

Query: 2850 ILKFCLVGWGIPAIMVAITVSVK--KDLYGTLS----PTTPFCWIKDDSIFYISVVAYFC 2903
            ILKFC++GWG+PA++V++ ++ +   ++YG  S        FCWI+D  IFY++   YF 
Sbjct: 971  ILKFCIIGWGLPALVVSVVLASRNNNEVYGKESYGKEKGDEFCWIQDPVIFYVTCAGYFG 1030

Query: 2904 LIFLMNLSMFCTVLVQL---NSVKSQIQKTRRKMILHDLKGTMSLTFLLGLTWGFAFFAW 2960
            ++F +N++MF  V+VQ+   N  +S   +T R+ +L +L+  +SLTFLLG+TWGFAFFAW
Sbjct: 1031 VMFFLNIAMFIVVMVQICGRNGKRS--NRTLREEVLRNLRSVVSLTFLLGMTWGFAFFAW 1088

Query: 2961 GPMRNFFLYLFAIFNTLQGFFIFVFHCVMKESVREQWQIHLCCGWLRLDNSSDGSSRCQI 3020
            GP+   F+YLF+IFN+LQG FIF+FHC MKE+V++QW+ HLCCG  RL ++SD S     
Sbjct: 1089 GPLNIPFMYLFSIFNSLQGLFIFIFHCAMKENVQKQWRRHLCCGRFRLADNSDWSKTATN 1148

Query: 3021 KVGYKQEGLKKIFEHKLLTPSLKSTATSSTFKSLGSA 3057
             +    + L K     L + S+ S +T  T KS  S+
Sbjct: 1149 IIKKSSDNLGK----SLSSSSIGSNSTYLTSKSKSSS 1181



 Score = 55.1 bits (131), Expect = 1e-06
 Identities = 59/262 (22%), Positives = 106/262 (40%), Gaps = 28/262 (10%)

Query: 21  FLSDTLSLKGKKLDFFGRGDTY---VSLIDTIPELSRFTACIDLVFMDDNSRYWMAFSY- 76
           ++   +SL+ +K+      D Y   V+   +IPELS FT C +   +      W AFSY 
Sbjct: 146 YIRVAVSLRNQKVILPQTSDAYQVSVAKSISIPELSAFTLCFEATKVGHEDSDWTAFSYS 205

Query: 77  ---ITNNALLGREDIDLGLAGDHQQLILYRLGKTFSIRHHLASFQWHTICLIWDGVKGKL 133
               T     G+      L+    + +L         +  + +  +  +CL+W+   G +
Sbjct: 206 NASFTQLLSFGKAKSGYFLSISDSKCLLNN-ALPVKEKEDIFAESFEQLCLVWNNSLGSI 264

Query: 134 ELFLNKERILEVTDQPHNLTP----HGTLFLGHFLKNESSEVKSMMRSFPGSLYYFQLWD 189
              +N +R  E       ++     +G L LG    N++  V     S  G +Y F+LW+
Sbjct: 265 G--VNFKRNYETVPCDSTISKVIPGNGKLLLG---SNQNEIV-----SLKGDIYNFRLWN 314

Query: 190 HILENE--EFMKC-LDGNIVSWEEDVWLVNKIIPTVDRTLRCFVPENMTIQEKSTTVSQQ 246
             +  +    + C + GN+V W+ D W +  +    +  L C    +  I   +  ++  
Sbjct: 315 FTMNAKILSNLSCNVKGNVVDWQNDFWNIPNLALKAESNLSC---GSYLIPLPAAELASC 371

Query: 247 IDMTTPSQITGVKPQNTAHSST 268
            D+ T  Q T   P  T  + T
Sbjct: 372 ADLGTLCQATVNSPSTTPPTVT 393


>gi|50355941 G protein-coupled receptor 126 beta 1 precursor [Homo
            sapiens]
          Length = 1250

 Score =  466 bits (1198), Expect = e-130
 Identities = 313/877 (35%), Positives = 474/877 (54%), Gaps = 100/877 (11%)

Query: 2206 ATVSSPISSFFETTWLDSTPSFLSTEASTSPTATKSTVS--FYNVEMSFSVFVEEPRIPI 2263
            ATV+SP           +TP  ++T    +    K       Y + +     +  P + +
Sbjct: 380  ATVNSP----------STTPPTVTTNMPVTNRIDKQRNDGIIYRISVVIQNILRHPEVKV 429

Query: 2264 TSVINEFTENSLNSIFQNSEFSLATLETQIKSRDISEEEMVMDRAILEQREGQEMATISY 2323
             S + E+    LNS FQN  +++  +          E+++ + R++ ++      A + Y
Sbjct: 430  QSKVAEW----LNSTFQNWNYTVYVVNISFHL-SAGEDKIKVKRSLEDEPRLVLWALLVY 484

Query: 2324 VPYSCVCQVIIKASSSLASSELMRKIKSKIHGNFTHGNFTQDQLTLLVNCEHVAVKKLEP 2383
                          ++  ++ L  KI   I       N + D+   L     V V++L  
Sbjct: 485  --------------NATNNTNLEGKI---IQQKLLKNNESLDEGLRL---HTVNVRQL-- 522

Query: 2384 GNCKADETASKYKGTYKWLLTNPTETAQTRCIKNEDGNATRFCSISINTGKSQWEKPKFK 2443
            G+C A E     KG Y W    P+E     C      +A+R C  +       +  P   
Sbjct: 523  GHCLAMEEP---KGYY-WPSIQPSEYVLP-CPDKPGFSASRICFYNATNPLVTYWGP--- 574

Query: 2444 QCKLLQELPDKIVDLANITISDENAEDVAEHILNLINESPALGKEETKIIVSKISDISQC 2503
                        VD++N     + A +VA  ILNL  +   L       IV ++  I   
Sbjct: 575  ------------VDISNCL---KEANEVANQILNLTADGQNLTSANITNIVEQVKRIVNK 619

Query: 2504 DE-ISMNLTHVMLQIINVVLEKQNNSASDLHEISNEILRIIERTGHKMEF-SGQIANLTV 2561
            +E I + L   ++ I + +L   ++S SDL E S+E L+ I+    K++  S    N+T 
Sbjct: 620  EENIDITLGSTLMNIFSNIL---SSSDSDLLESSSEALKTIDELAFKIDLNSTSHVNITT 676

Query: 2562 AGLALAV---LRGDHTFDGMAFSIHSYEEGTDPEIFLGNVPVGGI--LASIYLPKSLTER 2616
              LAL+V   L G +     +  + S  E      F  +   G +  LAS+ LP +L E 
Sbjct: 677  RNLALSVSSLLPGTNAISNFSIGLPSNNES----YFQMDFESGQVDPLASVILPPNLLEN 732

Query: 2617 IPLSN---LQTILFNFFGQTSLFKTKNVT-KALTTYVVSASISDDMFIQNLADPVVITLQ 2672
            +   +   ++   F FF +T LF+      K L +YV++ SI + + IQNL DPV I ++
Sbjct: 733  LSPEDSVLVRRAQFTFFNKTGLFQDVGPQRKTLVSYVMACSIGN-ITIQNLKDPVQIKIK 791

Query: 2673 HIGGNQNYGQVHCAFWDFENNNGLGGWNSSGCKV-KETNVNYTICQCDHLTHFGVLMDLS 2731
            H    + +  + CAFWD   N   GGWN+SGC   ++++ + T+C C+H THFGVLMDL 
Sbjct: 792  HTRTQEVHHPI-CAFWDLNKNKSFGGWNTSGCVAHRDSDASETVCLCNHFTHFGVLMDLP 850

Query: 2732 RST--VDSVNEQILALITYTGCGISSIFLGVAVVTYIAFHKLRKDYPAKILINLCTALLM 2789
            RS   +D+ N ++L  I+Y GCGIS+IF    ++TY+AF KLR+DYP+KIL+NL TALL 
Sbjct: 851  RSASQLDARNTKVLTFISYIGCGISAIFSAATLLTYVAFEKLRRDYPSKILMNLSTALLF 910

Query: 2790 LNLVFLINSWLSSFQKVGVCITAAVALHYFLLVSFTWMGLEAVHMYLALVKVFNIYIPNY 2849
            LNL+FL++ W++SF   G+CI  AV LH+FLL +FTWMGLEA+HMY+ALVKVFN YI  Y
Sbjct: 911  LNLLFLLDGWITSFNVDGLCIAVAVLLHFFLLATFTWMGLEAIHMYIALVKVFNTYIRRY 970

Query: 2850 ILKFCLVGWGIPAIMVAITVSVK--KDLYGTLS----PTTPFCWIKDDSIFYISVVAYFC 2903
            ILKFC++GWG+PA++V++ ++ +   ++YG  S        FCWI+D  IFY++   YF 
Sbjct: 971  ILKFCIIGWGLPALVVSVVLASRNNNEVYGKESYGKEKGDEFCWIQDPVIFYVTCAGYFG 1030

Query: 2904 LIFLMNLSMFCTVLVQL---NSVKSQIQKTRRKMILHDLKGTMSLTFLLGLTWGFAFFAW 2960
            ++F +N++MF  V+VQ+   N  +S   +T R+ +L +L+  +SLTFLLG+TWGFAFFAW
Sbjct: 1031 VMFFLNIAMFIVVMVQICGRNGKRS--NRTLREEVLRNLRSVVSLTFLLGMTWGFAFFAW 1088

Query: 2961 GPMRNFFLYLFAIFNTLQGFFIFVFHCVMKESVREQWQIHLCCGWLRLDNSSDGSSRCQI 3020
            GP+   F+YLF+IFN+LQG FIF+FHC MKE+V++QW+ HLCCG  RL ++SD S     
Sbjct: 1089 GPLNIPFMYLFSIFNSLQGLFIFIFHCAMKENVQKQWRRHLCCGRFRLADNSDWSKTATN 1148

Query: 3021 KVGYKQEGLKKIFEHKLLTPSLKSTATSSTFKSLGSA 3057
             +    + L K     L + S+ S +T  T KS  S+
Sbjct: 1149 IIKKSSDNLGK----SLSSSSIGSNSTYLTSKSKSSS 1181



 Score = 55.1 bits (131), Expect = 1e-06
 Identities = 59/262 (22%), Positives = 106/262 (40%), Gaps = 28/262 (10%)

Query: 21  FLSDTLSLKGKKLDFFGRGDTY---VSLIDTIPELSRFTACIDLVFMDDNSRYWMAFSY- 76
           ++   +SL+ +K+      D Y   V+   +IPELS FT C +   +      W AFSY 
Sbjct: 146 YIRVAVSLRNQKVILPQTSDAYQVSVAKSISIPELSAFTLCFEATKVGHEDSDWTAFSYS 205

Query: 77  ---ITNNALLGREDIDLGLAGDHQQLILYRLGKTFSIRHHLASFQWHTICLIWDGVKGKL 133
               T     G+      L+    + +L         +  + +  +  +CL+W+   G +
Sbjct: 206 NASFTQLLSFGKAKSGYFLSISDSKCLLNN-ALPVKEKEDIFAESFEQLCLVWNNSLGSI 264

Query: 134 ELFLNKERILEVTDQPHNLTP----HGTLFLGHFLKNESSEVKSMMRSFPGSLYYFQLWD 189
              +N +R  E       ++     +G L LG    N++  V     S  G +Y F+LW+
Sbjct: 265 G--VNFKRNYETVPCDSTISKVIPGNGKLLLG---SNQNEIV-----SLKGDIYNFRLWN 314

Query: 190 HILENE--EFMKC-LDGNIVSWEEDVWLVNKIIPTVDRTLRCFVPENMTIQEKSTTVSQQ 246
             +  +    + C + GN+V W+ D W +  +    +  L C    +  I   +  ++  
Sbjct: 315 FTMNAKILSNLSCNVKGNVVDWQNDFWNIPNLALKAESNLSC---GSYLIPLPAAELASC 371

Query: 247 IDMTTPSQITGVKPQNTAHSST 268
            D+ T  Q T   P  T  + T
Sbjct: 372 ADLGTLCQATVNSPSTTPPTVT 393


>gi|74048422 G protein-coupled receptor 126 alpha 2 precursor [Homo
            sapiens]
          Length = 1193

 Score =  465 bits (1196), Expect = e-130
 Identities = 265/625 (42%), Positives = 387/625 (61%), Gaps = 41/625 (6%)

Query: 2456 VDLANITISDENAEDVAEHILNLINESPALGKEETKIIVSKISDISQCDE-ISMNLTHVM 2514
            VD++N     + A +VA  ILNL  +   L       IV ++  I   +E I + L   +
Sbjct: 547  VDISNCL---KEANEVANQILNLTADGQNLTSANITNIVEQVKRIVNKEENIDITLGSTL 603

Query: 2515 LQIINVVLEKQNNSASDLHEISNEILRIIERTGHKMEF-SGQIANLTVAGLALAV---LR 2570
            + I + +L   ++S SDL E S+E L+ I+    K++  S    N+T   LAL+V   L 
Sbjct: 604  MNIFSNIL---SSSDSDLLESSSEALKTIDELAFKIDLNSTSHVNITTRNLALSVSSLLP 660

Query: 2571 GDHTFDGMAFSIHSYEEGTDPEIFLGNVPVGGI--LASIYLPKSLTERIPLSN---LQTI 2625
            G +     +  + S  E      F  +   G +  LAS+ LP +L E +   +   ++  
Sbjct: 661  GTNAISNFSIGLPSNNES----YFQMDFESGQVDPLASVILPPNLLENLSPEDSVLVRRA 716

Query: 2626 LFNFFGQTSLFKTKNVT-KALTTYVVSASISDDMFIQNLADPVVITLQHIGGNQNYGQVH 2684
             F FF +T LF+      K L +YV++ SI + + IQNL DPV I ++H    + +  + 
Sbjct: 717  QFTFFNKTGLFQDVGPQRKTLVSYVMACSIGN-ITIQNLKDPVQIKIKHTRTQEVHHPI- 774

Query: 2685 CAFWDFENNNGLGGWNSSGCKV-KETNVNYTICQCDHLTHFGVLMDLSRST--VDSVNEQ 2741
            CAFWD   N   GGWN+SGC   ++++ + T+C C+H THFGVLMDL RS   +D+ N +
Sbjct: 775  CAFWDLNKNKSFGGWNTSGCVAHRDSDASETVCLCNHFTHFGVLMDLPRSASQLDARNTK 834

Query: 2742 ILALITYTGCGISSIFLGVAVVTYIAFHKLRKDYPAKILINLCTALLMLNLVFLINSWLS 2801
            +L  I+Y GCGIS+IF    ++TY+AF KLR+DYP+KIL+NL TALL LNL+FL++ W++
Sbjct: 835  VLTFISYIGCGISAIFSAATLLTYVAFEKLRRDYPSKILMNLSTALLFLNLLFLLDGWIT 894

Query: 2802 SFQKVGVCITAAVALHYFLLVSFTWMGLEAVHMYLALVKVFNIYIPNYILKFCLVGWGIP 2861
            SF   G+CI  AV LH+FLL +FTWMGLEA+HMY+ALVKVFN YI  YILKFC++GWG+P
Sbjct: 895  SFNVDGLCIAVAVLLHFFLLATFTWMGLEAIHMYIALVKVFNTYIRRYILKFCIIGWGLP 954

Query: 2862 AIMVAITVSVK--KDLYGTLS----PTTPFCWIKDDSIFYISVVAYFCLIFLMNLSMFCT 2915
            A++V++ ++ +   ++YG  S        FCWI+D  IFY++   YF ++F +N++MF  
Sbjct: 955  ALVVSVVLASRNNNEVYGKESYGKEKGDEFCWIQDPVIFYVTCAGYFGVMFFLNIAMFIV 1014

Query: 2916 VLVQL---NSVKSQIQKTRRKMILHDLKGTMSLTFLLGLTWGFAFFAWGPMRNFFLYLFA 2972
            V+VQ+   N  +S   +T R+ +L +L+  +SLTFLLG+TWGFAFFAWGP+   F+YLF+
Sbjct: 1015 VMVQICGRNGKRS--NRTLREEVLRNLRSVVSLTFLLGMTWGFAFFAWGPLNIPFMYLFS 1072

Query: 2973 IFNTLQGFFIFVFHCVMKESVREQWQIHLCCGWLRLDNSSDGSSRCQIKVGYKQEGLKKI 3032
            IFN+LQG FIF+FHC MKE+V++QW+ HLCCG  RL ++SD S      +    + L K 
Sbjct: 1073 IFNSLQGLFIFIFHCAMKENVQKQWRRHLCCGRFRLADNSDWSKTATNIIKKSSDNLGK- 1131

Query: 3033 FEHKLLTPSLKSTATSSTFKSLGSA 3057
                L + S+ S +T  T KS  S+
Sbjct: 1132 ---SLSSSSIGSNSTYLTSKSKSSS 1153



 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 51/222 (22%), Positives = 92/222 (41%), Gaps = 25/222 (11%)

Query: 21  FLSDTLSLKGKKLDFFGRGDTY---VSLIDTIPELSRFTACIDLVFMDDNSRYWMAFSY- 76
           ++   +SL+ +K+      D Y   V+   +IPELS FT C +   +      W AFSY 
Sbjct: 146 YIRVAVSLRNQKVILPQTSDAYQVSVAKSISIPELSAFTLCFEATKVGHEDSDWTAFSYS 205

Query: 77  ---ITNNALLGREDIDLGLAGDHQQLILYRLGKTFSIRHHLASFQWHTICLIWDGVKGKL 133
               T     G+      L+    + +L         +  + +  +  +CL+W+   G +
Sbjct: 206 NASFTQLLSFGKAKSGYFLSISDSKCLLNN-ALPVKEKEDIFAESFEQLCLVWNNSLGSI 264

Query: 134 ELFLNKERILEVTDQPHNLTP----HGTLFLGHFLKNESSEVKSMMRSFPGSLYYFQLWD 189
              +N +R  E       ++     +G L LG    N++  V     S  G +Y F+LW+
Sbjct: 265 G--VNFKRNYETVPCDSTISKVIPGNGKLLLG---SNQNEIV-----SLKGDIYNFRLWN 314

Query: 190 HILENE--EFMKC-LDGNIVSWEEDVWLVNKIIPTVDRTLRC 228
             +  +    + C + GN+V W+ D W +  +    +  L C
Sbjct: 315 FTMNAKILSNLSCNVKGNVVDWQNDFWNIPNLALKAESNLSC 356


>gi|74048403 G protein-coupled receptor 126 beta 2 precursor [Homo
            sapiens]
          Length = 1222

 Score =  465 bits (1196), Expect = e-130
 Identities = 265/625 (42%), Positives = 387/625 (61%), Gaps = 41/625 (6%)

Query: 2456 VDLANITISDENAEDVAEHILNLINESPALGKEETKIIVSKISDISQCDE-ISMNLTHVM 2514
            VD++N     + A +VA  ILNL  +   L       IV ++  I   +E I + L   +
Sbjct: 547  VDISNCL---KEANEVANQILNLTADGQNLTSANITNIVEQVKRIVNKEENIDITLGSTL 603

Query: 2515 LQIINVVLEKQNNSASDLHEISNEILRIIERTGHKMEF-SGQIANLTVAGLALAV---LR 2570
            + I + +L   ++S SDL E S+E L+ I+    K++  S    N+T   LAL+V   L 
Sbjct: 604  MNIFSNIL---SSSDSDLLESSSEALKTIDELAFKIDLNSTSHVNITTRNLALSVSSLLP 660

Query: 2571 GDHTFDGMAFSIHSYEEGTDPEIFLGNVPVGGI--LASIYLPKSLTERIPLSN---LQTI 2625
            G +     +  + S  E      F  +   G +  LAS+ LP +L E +   +   ++  
Sbjct: 661  GTNAISNFSIGLPSNNES----YFQMDFESGQVDPLASVILPPNLLENLSPEDSVLVRRA 716

Query: 2626 LFNFFGQTSLFKTKNVT-KALTTYVVSASISDDMFIQNLADPVVITLQHIGGNQNYGQVH 2684
             F FF +T LF+      K L +YV++ SI + + IQNL DPV I ++H    + +  + 
Sbjct: 717  QFTFFNKTGLFQDVGPQRKTLVSYVMACSIGN-ITIQNLKDPVQIKIKHTRTQEVHHPI- 774

Query: 2685 CAFWDFENNNGLGGWNSSGCKV-KETNVNYTICQCDHLTHFGVLMDLSRST--VDSVNEQ 2741
            CAFWD   N   GGWN+SGC   ++++ + T+C C+H THFGVLMDL RS   +D+ N +
Sbjct: 775  CAFWDLNKNKSFGGWNTSGCVAHRDSDASETVCLCNHFTHFGVLMDLPRSASQLDARNTK 834

Query: 2742 ILALITYTGCGISSIFLGVAVVTYIAFHKLRKDYPAKILINLCTALLMLNLVFLINSWLS 2801
            +L  I+Y GCGIS+IF    ++TY+AF KLR+DYP+KIL+NL TALL LNL+FL++ W++
Sbjct: 835  VLTFISYIGCGISAIFSAATLLTYVAFEKLRRDYPSKILMNLSTALLFLNLLFLLDGWIT 894

Query: 2802 SFQKVGVCITAAVALHYFLLVSFTWMGLEAVHMYLALVKVFNIYIPNYILKFCLVGWGIP 2861
            SF   G+CI  AV LH+FLL +FTWMGLEA+HMY+ALVKVFN YI  YILKFC++GWG+P
Sbjct: 895  SFNVDGLCIAVAVLLHFFLLATFTWMGLEAIHMYIALVKVFNTYIRRYILKFCIIGWGLP 954

Query: 2862 AIMVAITVSVK--KDLYGTLS----PTTPFCWIKDDSIFYISVVAYFCLIFLMNLSMFCT 2915
            A++V++ ++ +   ++YG  S        FCWI+D  IFY++   YF ++F +N++MF  
Sbjct: 955  ALVVSVVLASRNNNEVYGKESYGKEKGDEFCWIQDPVIFYVTCAGYFGVMFFLNIAMFIV 1014

Query: 2916 VLVQL---NSVKSQIQKTRRKMILHDLKGTMSLTFLLGLTWGFAFFAWGPMRNFFLYLFA 2972
            V+VQ+   N  +S   +T R+ +L +L+  +SLTFLLG+TWGFAFFAWGP+   F+YLF+
Sbjct: 1015 VMVQICGRNGKRS--NRTLREEVLRNLRSVVSLTFLLGMTWGFAFFAWGPLNIPFMYLFS 1072

Query: 2973 IFNTLQGFFIFVFHCVMKESVREQWQIHLCCGWLRLDNSSDGSSRCQIKVGYKQEGLKKI 3032
            IFN+LQG FIF+FHC MKE+V++QW+ HLCCG  RL ++SD S      +    + L K 
Sbjct: 1073 IFNSLQGLFIFIFHCAMKENVQKQWRRHLCCGRFRLADNSDWSKTATNIIKKSSDNLGK- 1131

Query: 3033 FEHKLLTPSLKSTATSSTFKSLGSA 3057
                L + S+ S +T  T KS  S+
Sbjct: 1132 ---SLSSSSIGSNSTYLTSKSKSSS 1153



 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 51/222 (22%), Positives = 92/222 (41%), Gaps = 25/222 (11%)

Query: 21  FLSDTLSLKGKKLDFFGRGDTY---VSLIDTIPELSRFTACIDLVFMDDNSRYWMAFSY- 76
           ++   +SL+ +K+      D Y   V+   +IPELS FT C +   +      W AFSY 
Sbjct: 146 YIRVAVSLRNQKVILPQTSDAYQVSVAKSISIPELSAFTLCFEATKVGHEDSDWTAFSYS 205

Query: 77  ---ITNNALLGREDIDLGLAGDHQQLILYRLGKTFSIRHHLASFQWHTICLIWDGVKGKL 133
               T     G+      L+    + +L         +  + +  +  +CL+W+   G +
Sbjct: 206 NASFTQLLSFGKAKSGYFLSISDSKCLLNN-ALPVKEKEDIFAESFEQLCLVWNNSLGSI 264

Query: 134 ELFLNKERILEVTDQPHNLTP----HGTLFLGHFLKNESSEVKSMMRSFPGSLYYFQLWD 189
              +N +R  E       ++     +G L LG    N++  V     S  G +Y F+LW+
Sbjct: 265 G--VNFKRNYETVPCDSTISKVIPGNGKLLLG---SNQNEIV-----SLKGDIYNFRLWN 314

Query: 190 HILENE--EFMKC-LDGNIVSWEEDVWLVNKIIPTVDRTLRC 228
             +  +    + C + GN+V W+ D W +  +    +  L C
Sbjct: 315 FTMNAKILSNLSCNVKGNVVDWQNDFWNIPNLALKAESNLSC 356


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score =  351 bits (900), Expect = 7e-96
 Identities = 474/2062 (22%), Positives = 740/2062 (35%), Gaps = 155/2062 (7%)

Query: 235  TIQEKSTTVSQQIDMTTPSQITGVKPQNTAHSSTLLSQSIPIFATDYTTISYSNTTSPPL 294
            T+    T    Q   TTP   T         + T    + PI  T         TT  P 
Sbjct: 1906 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT---------TTVTPT 1956

Query: 295  ETMTAQKILKTLVDETATFAVDVLSTSSAISLPTQSISIDNTTNSMKKTKSPSSESTKTT 354
             T T  +   T    T T    V  T +     T + +   TT ++  T +P+   T TT
Sbjct: 1957 PTPTGTQTPTTTPITTTT---TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2013

Query: 355  KMVEAMATEIFQPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFSTIESTSMST 414
              +    T +   PTP+   + +     +  + T         T TT+  +T  + + + 
Sbjct: 2014 TPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2072

Query: 415  TPCLKQKSTNTGALPISTAGQEFIESTAAGTVPWFTVEKTSPASTHVGTASSFPPEPVLI 474
            TP   Q  T T   PI+T        T  GT         +P +T + T ++  P P   
Sbjct: 2073 TPTGTQTPTTT---PITTTTTVTPTPTPTGT--------QTPTTTPITTTTTVTPTPTPT 2121

Query: 475  STAAPVDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETTPAPRTAETELTSTNFQD 534
             T  P  +      T  P  T       T   +T  T  +  TP P   +T  T+     
Sbjct: 2122 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQTPTTTPITTT 2180

Query: 535  VSLPRVEDAMSTSMSKETSSKTFSFLT-SFSFTGTESVQTVIDAEATRTALTPEITLAST 593
             ++        T     T   T + +T + + TGT++  T      T    TP  T   T
Sbjct: 2181 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2240

Query: 594  VAETMLSSTITGRVYTQNTPTADGHLLTLMSTRSASTSKAPESGPTSTTDEAAHLFSSNE 653
               T +++T T       TPT  G      +  + +T+  P   PT T        ++  
Sbjct: 2241 PTTTPITTTTT----VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2296

Query: 654  TIWTSRPDQALLASMNTTTILTFVPNENFTSAFHENTTYTEYLSATTNITPLKASPEGKG 713
            T+ T  P      +  TT I T        +     T  T  ++ TT +TP   +P   G
Sbjct: 2297 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTG 2352

Query: 714  TTANDATTARYTTAVSKLTSPWFANFSIVSGTTSITNMPEFKLTTLLLKTIPMSTKPANE 773
            T     T    TT V+   +P        +GT + T  P    TT+     P  T+    
Sbjct: 2353 TQTPTTTPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2404

Query: 774  LPLTPRETVVPSVDIISTLACIQPNFSTEESASET-----TQTEINGAIVFGGTTTPVP- 827
             P+T   TV P+     T        +T  + + T     TQT     I    T TP P 
Sbjct: 2405 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2464

Query: 828  ----KSATTQRLNATVT---RKEATSHYLMRKSTIAAVAEVSPFSTMLEVTDESAQRVTA 880
                ++ TT  +  T T       T       + I     V+P  T       +   +T 
Sbjct: 2465 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2524

Query: 881  SVTVSSFPDIEKLSTPLDNKTATTEVRESWLLTKLVKTTPRSSYNEMTEMFNFNHTYVAH 940
            + TV+  P      TP      TT        T     TP  +    T       T V  
Sbjct: 2525 TTTVTPTPTPTGTQTPTTTPITTT-------TTVTPTPTPTGTQTPTTTPIT-TTTTVTP 2576

Query: 941  WTSETSEGISAGSPTSGSTHIFGEPLGASTTRISETSFSTTPTDRTATSLSDGILPPQPT 1000
              + T       +P + +T +   P    T   + T  +TT T  T T    G   P  T
Sbjct: 2577 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTPTPTPTGTQTPTTT 2635

Query: 1001 AAHSSATPVPVTHMFSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMT 1060
               ++ T  P           ++ +   T VT +   T  +  +T+ ++  + ++ T   
Sbjct: 2636 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2695

Query: 1061 TALVPPLDQTASTTIVIVPTHGDLIRTTSEATVISVRKTSMAVPSLTETPFHSLRLSTPV 1120
            T    P     +TT  + PT       T   T I+   T    P+ T T       +TP+
Sbjct: 2696 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT---QTPTTTPI 2752

Query: 1121 TAKAETTLFSTSVDTVTP-----STHTLVCSKPPP-----DNIPPASSTHVISTTSTPEA 1170
            T     T   T   T TP     +T T V   P P         P ++T  ++ T TP  
Sbjct: 2753 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2812

Query: 1171 TQPISQVEETSTYALSFPYTFSGGGVVASLATGTTETSVVDETTPSHISANKLT--TSVN 1228
            TQ  +    T+T  ++ P     G    +    TT T+V    TP+       T  T+  
Sbjct: 2813 TQTPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2871

Query: 1229 SHISSSATYRVHTPVSIQLVTSTSVLSSDKDQMTISLGKTPRTMEVT---------EMSP 1279
            +   +       TP +  + T+T+V  +     T +   TP T   T           +P
Sbjct: 2872 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2931

Query: 1280 SKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSPSEIPLGTPSDGNLASSPTSGSTQI 1339
            +     + +  TP+   T T  P TT I++  T +P+  P GT +     ++P + +T +
Sbjct: 2932 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP---TTTPITTTTTV 2988

Query: 1340 TPTLTSSNTVGVHIPEMSTSLGKTALPSQALTITTFLCPEKESTSALPAYTPRTVEMIVN 1399
            TPT T + T       ++T+   T  P+   T T    P   +T+  P  TP   +    
Sbjct: 2989 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3048

Query: 1400 STYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINTTFSHLHSLRTQPEVTSVASFISEST 1459
            +   T        T+   T T + T+      I TT +   +       T   + I+ +T
Sbjct: 3049 TPITT-------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3101

Query: 1460 QTFPESLSLSTAGLYNDGFTVLSDRITTAFSVPNVPTMLPRESSMATSTPIYQMSSLPVN 1519
               P      T        T  +  ITT  +V   PT  P  +   T+TPI   +++   
Sbjct: 3102 TVTPTPTPTGTQ-------TPTTTPITTTTTV--TPTPTPTGTQTPTTTPITTTTTVTPT 3152

Query: 1520 VTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPATVSS 1579
             T   ++  + TP    T  + T  P   ++P T      + ++  P      TP T   
Sbjct: 3153 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3212

Query: 1580 DTSTRVGLFSTLLSSVTPRTTMTMQTSTLDVTPVIYAGATSKNKMVSSAFTTEMIEAPSR 1639
             T+T V    T   + TP TT    T+T+  TP      T     +++  T      P+ 
Sbjct: 3213 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3272

Query: 1640 I-TPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSP------LSSKSTGAISSIP 1692
              TPTT    T  T+    T PT       TP   TT  +P        + +T  I++  
Sbjct: 3273 TQTPTTTPITTTTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3331

Query: 1693 KTTFSPFLSATQQSSQADEATTLGILSGITNRSLSTVNSGTGVALTDTYSRITVPENMLS 1752
              T +P  + TQ  +     TT  +    T     T  + T +  T T +    P    +
Sbjct: 3332 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQT 3390

Query: 1753 PTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLLEKTSLTNYAT 1812
            PT      T+    V+P+ T   + +  T  + TTT    + T   T     T +T   T
Sbjct: 3391 PTTTPITTTT---TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT--TT 3445

Query: 1813 SLNTPVSYPPWTPSSATLPSLTSFVYSPHSTEAEISTPKTSPPPTSQMVEFPVLGTRMTS 1872
            +  TP   P  T +  T P  T+   +P  T     TP T+P  T+  V      T   +
Sbjct: 3446 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3505

Query: 1873 SNTQPLLMTS--WNIPTAEGSQFPISTTINVPTSNEMETETLHLVPGPLSTFTASQTGLV 1930
              T P+  T+     PT  G+Q P +T I         T T+   P P  T T + T + 
Sbjct: 3506 PTTTPITTTTTVTPTPTPTGTQTPTTTPITT-------TTTVTPTPTPTGTQTPTTTPIT 3558

Query: 1931 SKDVMAMSSIPMSGILPNHGLSENPSLSTSLRAITSTLADVK---HTFEKMTTSVTP--- 1984
            +   +  +  P     P    +  P  +T+    T T    +    T    TT+VTP   
Sbjct: 3559 TTTTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3614

Query: 1985 --GTTLPSILSGATSGSVISKSPILTWLLSSLPSGSPPATVSNAPHVMTSSTVEVSKST- 2041
              GT  P+     T+ +V   +P  T   +  P+ +P  T +      T +  +   +T 
Sbjct: 3615 PTGTQTPTTTPITTTTTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3671

Query: 2042 FLTSDMISAHPFTNLTTLPSATMSTILTRTIPTPTLGGITTGFPTSLPMSINVTDDIVYI 2101
              T+  ++  P    T  P+ T  T  T   PTPT  G  T  PT+ P++   T      
Sbjct: 3672 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPT 3729

Query: 2102 STHPEASSRTTITANPRTVSHPSSFSRKTMSPSTTDHTLSVGAMPLPSSTITSSWNRIPT 2161
             T  +  + T IT    T   P+     T +P+TT  T +    P P+ T T +    P 
Sbjct: 3730 PTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3787

Query: 2162 ASSPSTLIIPKPT---LDSLLNIMTTTSTVPGASFPLISTGVTYPFTATVS-SPISSFFE 2217
             ++ +    P PT     +   I TTT+  P  +     T  T P T T + +P  +   
Sbjct: 3788 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3847

Query: 2218 TTWLDSTPSFLSTEASTSPTAT 2239
            T    +TP   +T  + +PT T
Sbjct: 3848 TQTPTTTPITTTTTVTPTPTPT 3869



 Score =  350 bits (897), Expect = 2e-95
 Identities = 485/2090 (23%), Positives = 748/2090 (35%), Gaps = 160/2090 (7%)

Query: 235  TIQEKSTTVSQQIDMTTPSQITGVKPQNTAHSSTLLSQSIPIFATDYTTISYSNTTSPPL 294
            T+    T    Q   TTP   T         + T    + PI  T         TT  P 
Sbjct: 2274 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT---------TTVTPT 2324

Query: 295  ETMTAQKILKTLVDETATFAVDVLSTSSAISLPTQSISIDNTTNSMKKTKSPSSESTKTT 354
             T T  +   T    T T    V  T +     T + +   TT ++  T +P+   T TT
Sbjct: 2325 PTPTGTQTPTTTPITTTT---TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2381

Query: 355  KMVEAMATEIFQPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFSTIESTSMST 414
              +    T +   PTP+   + +     +  + T         T TT+  +T  + + + 
Sbjct: 2382 TPITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2440

Query: 415  TPCLKQKSTNTGALPISTAGQEFIESTAAGTVPWFTVEKTSPASTHVGTASSFPPEPVLI 474
            TP   Q  T T   PI+T        T  GT         +P +T + T ++  P P   
Sbjct: 2441 TPTGTQTPTTT---PITTTTTVTPTPTPTGT--------QTPTTTPITTTTTVTPTPTPT 2489

Query: 475  STAAPVDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETTPAPRTAETELTSTNFQD 534
             T  P  +      T  P  T       T   +T  T  +  TP P   +T  T+     
Sbjct: 2490 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-VTPTPTPTGTQTPTTTPITTT 2548

Query: 535  VSLPRVEDAMSTSMSKETSSKTFSFLTSFSF-TGTESVQTVIDAEATRTALTPEITLAST 593
             ++        T     T   T + +T     TGT++  T      T    TP  T   T
Sbjct: 2549 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2608

Query: 594  VAETMLSSTITGRVYTQNTPTADGHLLTLMSTRSASTSKAPESGPTSTTDEAAHLFSSNE 653
               T +++T T       TPT  G      +  + +T+  P   PT T        ++  
Sbjct: 2609 PTTTPITTTTT----VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2664

Query: 654  TIWTSRPDQALLASMNTTTILTFVPNENFTSAFHENTTYTEYLSATTNITPLKASPEGKG 713
            T+ T  P      +  TT I T        +     T  T  ++ TT +TP   +P   G
Sbjct: 2665 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTG 2720

Query: 714  TTANDATTARYTTAVSKLTSPWFANFSIVSGTTSITNMPEFKLTTLLLKTIPMSTKPANE 773
            T     T    TT V+   +P        +GT + T  P    TT+     P  T+    
Sbjct: 2721 TQTPTTTPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2772

Query: 774  LPLTPRETVVPSVDIISTLACIQPNFSTEESASET-----TQTEINGAIVFGGTTTPVP- 827
             P+T   TV P+     T        +T  + + T     TQT     I    T TP P 
Sbjct: 2773 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2832

Query: 828  ----KSATTQRLNATVT---RKEATSHYLMRKSTIAAVAEVSPFSTMLEVTDESAQRVTA 880
                ++ TT  +  T T       T       + I     V+P  T       +   +T 
Sbjct: 2833 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2892

Query: 881  SVTVSSFPDIEKLSTPLDNKTATTEVRESWLLTKLVKTTPRSSYNEMTEMFNFNHTYVAH 940
            + TV+  P      TP      TT        T     TP  +    T       T V  
Sbjct: 2893 TTTVTPTPTPTGTQTPTTTPITTTT-------TVTPTPTPTGTQTPTTTPITTTTT-VTP 2944

Query: 941  WTSETSEGISAGSPTSGSTHIFGEPLGASTTRISETSFSTTPTDRTATSLSDGILPPQPT 1000
              + T       +P + +T +   P    T   + T  +TT T  T T    G   P  T
Sbjct: 2945 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTT 3003

Query: 1001 AAHSSATPVPVTHMFSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMT 1060
               ++ T  P           ++ +   T VT +   T  +  +T+ ++  + ++ T   
Sbjct: 3004 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3063

Query: 1061 TALVPPLDQTASTTIVIVPTHGDLIRTTSEATVISVRKTSMAVPSLTETPFHSLRLSTPV 1120
            T    P     +TT  + PT       T   T I+   T    P+ T T   +   +TP+
Sbjct: 3064 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT---TTPI 3120

Query: 1121 TAKAETTLFSTSVDTVTPSTH-----TLVCSKPPPDNIP-----PASSTHVISTTSTPEA 1170
            T     T   T   T TP+T      T V   P P         P ++T  ++ T TP  
Sbjct: 3121 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3180

Query: 1171 TQPISQVEETSTYALSFPYTFSGGGVVASLATGTTETSVVDETTPSHISANKLT--TSVN 1228
            TQ  +    T+T  ++ P     G    +    TT T+V    TP+       T  T+  
Sbjct: 3181 TQTPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3239

Query: 1229 SHISSSATYRVHTPVSIQLVTSTSVLSSDKDQMTISLGKTPRTMEVT---------EMSP 1279
            +   +       TP +  + T+T+V  +     T +   TP T   T           +P
Sbjct: 3240 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3299

Query: 1280 SKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSPSEIPLGTPSDGNLASSPTSGSTQI 1339
            +     + +  TP+   T T  P TT I++  T +P+  P GT +     ++P + +T +
Sbjct: 3300 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP---TTTPITTTTTV 3356

Query: 1340 TPTLTSSNTVGVHIPEMSTSLGKTALPSQALTITTFLCPEKESTSALPAYTPRTVEMIVN 1399
            TPT T + T       ++T+   T  P+   T T    P   +T+  P  TP   +    
Sbjct: 3357 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3416

Query: 1400 STYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINTTFSHLHSLRTQPEVTSVASFISEST 1459
            +   T        T+   T T + T+      I TT +   +       T   + I+ +T
Sbjct: 3417 TPITT-------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3469

Query: 1460 QTFPESLSLSTAGLYNDGFTVLSDRITTAFSVPNVPTMLPRESSMATSTPIYQMSSLPVN 1519
               P      T        T  +  ITT  +V   PT  P  +   T+TPI   +++   
Sbjct: 3470 TVTPTPTPTGTQ-------TPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPT 3520

Query: 1520 VTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPATVSS 1579
             T   ++  + TP    T  + T  P   ++P T      + ++  P      TP T   
Sbjct: 3521 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3580

Query: 1580 DTSTRVGLFSTLLSSVTPRTTMTMQTSTLDVTPVIYAGATSKNKMVSSAFTTEMIEAPSR 1639
             T+T V    T   + TP TT    T+T+  TP      T     +++  T      P+ 
Sbjct: 3581 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3640

Query: 1640 I-TPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSPL------SSKSTGAISSIP 1692
              TPTT    T  T+    T PT       TP   TT  +P        + +T  I++  
Sbjct: 3641 TQTPTTTPITTTTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3699

Query: 1693 KTTFSPFLSATQQSSQADEATTLGILSGITNRSLSTVNSGTGVALTDTYSRITVPENMLS 1752
              T +P  + TQ  +     TT  +    T     T  + T +  T T +    P    +
Sbjct: 3700 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQT 3758

Query: 1753 PTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLLEKTSLTNYAT 1812
            PT      T+    V+P+ T   + +  T  + TTT    + T   T     T +T   T
Sbjct: 3759 PTTTPITTTT---TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT--T 3813

Query: 1813 SLNTPVSYPPWTPSSATLPSLTSFVYSPHSTEAEISTPKTSPPPTSQMVEFPVLGTRMTS 1872
            +  TP   P  T +  T P  T+   +P  T     TP T+P  T+  V      T   +
Sbjct: 3814 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3873

Query: 1873 SNTQPLLMTSW--NIPTAEGSQFPISTTINVPTSNEMETETLHLVPGPLSTFTASQTGLV 1930
              T P+  T+     PT  G+Q P +T I   T       T+   P P  T T + T + 
Sbjct: 3874 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-------TVTPTPTPTGTQTPTTTPIT 3926

Query: 1931 SKDVMAMSSIPMSGILPNHGLSENPSLSTSLRAITSTLADVKHTFEKMTTSVTP-----G 1985
            +   +  +  P     P        +  T     T T      T    TT+VTP     G
Sbjct: 3927 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTG 3985

Query: 1986 TTLPSILSGATSGSVISKSPILTWLLSSLPSGSPPATVSNAPHVMTSSTVEVSKST-FLT 2044
            T  P+     T+ +V   +P  T   +  P+ +P  T +      T +  +   +T   T
Sbjct: 3986 TQTPTTTPITTTTTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4042

Query: 2045 SDMISAHPFTNLTTLPSATMSTILTRTIPTPTLGGITTGFPTSLPMSINVTDDIVYISTH 2104
            +  ++  P    T  P+ T  T  T   PTPT  G  T  PT+ P++   T       T 
Sbjct: 4043 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTG 4100

Query: 2105 PEASSRTTITANPRTVSHPSSFSRKTMSPSTTDHTLSVGAMPLPSSTITSSWNRIPTASS 2164
             +  + T IT    T   P+     T +P+TT  T +    P P+ T T +    P  ++
Sbjct: 4101 TQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 4158

Query: 2165 PSTLIIPKP--TLDSLLNIMTTTSTVPGASFPLISTGV-TYPFTATVSSPISSFFETTWL 2221
             +    P P  T       +TTT+TV     P   TG  T P T T ++PI+   E T  
Sbjct: 4159 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP---TGTQTGPPTHTSTAPIA---ELTTS 4212

Query: 2222 DSTP--SFLSTEASTSPTATKSTVSFYN----VEMSFSVFVEEPRIPITS 2265
            +  P  S   T  STS   T+ST         +EM+ +     P  P T+
Sbjct: 4213 NPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTT 4262



 Score =  348 bits (892), Expect = 6e-95
 Identities = 468/2063 (22%), Positives = 736/2063 (35%), Gaps = 157/2063 (7%)

Query: 235  TIQEKSTTVSQQIDMTTPSQITGVKPQNTAHSSTLLSQSIPIFATDYTTISYSNTTSPPL 294
            T+    T    Q   TTP   T         + T    + PI  T         TT  P 
Sbjct: 1975 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT---------TTVTPT 2025

Query: 295  ETMTAQKILKTLVDETATFAVDVLSTSSAISLPTQSISIDNTTNSMKKTKSPSSESTKTT 354
             T T  +   T    T T    V  T +     T + +   TT ++  T +P+   T TT
Sbjct: 2026 PTPTGTQTPTTTPITTTT---TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2082

Query: 355  KMVEAMATEIFQPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFSTIESTSMST 414
              +    T +   PTP+   + +     +  + T         T TT+  +T  + + + 
Sbjct: 2083 TPITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2141

Query: 415  TPCLKQKSTNTGALPISTAGQEFIESTAAGTVPWFTVEKTSPASTHVGTASSFPPEPVLI 474
            TP   Q  T T   PI+T        T  GT         +P +T + T ++  P P   
Sbjct: 2142 TPTGTQTPTTT---PITTTTTVTPTPTPTGT--------QTPTTTPITTTTTVTPTPTPT 2190

Query: 475  STAAPVDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETTPAPRTAETELTSTNFQD 534
             T  P  +      T  P  T       T   +T  T  +  TP P   +T  T+     
Sbjct: 2191 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-VTPTPTPTGTQTPTTTPITTT 2249

Query: 535  VSLPRVEDAMSTSMSKETSSKTFSFLTSFSF-TGTESVQTVIDAEATRTALTPEITLAST 593
             ++        T     T   T + +T     TGT++  T      T    TP  T   T
Sbjct: 2250 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2309

Query: 594  VAETMLSSTITGRVYTQNTPTADGHLLTLMSTRSASTSKAPESGPTSTTDEAAHLFSSNE 653
               T +++T T       TPT  G      +  + +T+  P   PT T        ++  
Sbjct: 2310 PTTTPITTTTT----VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2365

Query: 654  TIWTSRPDQALLASMNTTTILTFVPNENFTSAFHENTTYTEYLSATTNITPLKASPEGKG 713
            T+ T  P      +  TT I T        +     T  T  ++ TT +TP   +P   G
Sbjct: 2366 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTG 2421

Query: 714  TTANDATTARYTTAVSKLTSPWFANFSIVSGTTSITNMPEFKLTTLLLKTIPMSTKPANE 773
            T     T    TT V+   +P        +GT + T  P    TT+     P  T+    
Sbjct: 2422 TQTPTTTPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2473

Query: 774  LPLTPRETVVPSVDIISTLACIQPNFSTEESASET-----TQTEINGAIVFGGTTTPVP- 827
             P+T   TV P+     T        +T  + + T     TQT     I    T TP P 
Sbjct: 2474 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2533

Query: 828  ----KSATTQRLNATVT---RKEATSHYLMRKSTIAAVAEVSPFSTMLEVTDESAQRVTA 880
                ++ TT  +  T T       T       + I     V+P  T       +   +T 
Sbjct: 2534 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2593

Query: 881  SVTVSSFPDIEKLSTPLDNKTATTEVRESWLLTKLVKTTPRSSYNEMTEMFNFNHTYVAH 940
            + TV+  P      TP      TT        T     TP  +    T       T V  
Sbjct: 2594 TTTVTPTPTPTGTQTPTTTPITTTT-------TVTPTPTPTGTQTPTTTPITTTTT-VTP 2645

Query: 941  WTSETSEGISAGSPTSGSTHIFGEPLGASTTRISETSFSTTPTDRTATSLSDGILPPQPT 1000
              + T       +P + +T +   P    T   + T  +TT T  T T    G   P  T
Sbjct: 2646 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTT 2704

Query: 1001 AAHSSATPVPVTHMFSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMT 1060
               ++ T  P           ++ +   T VT +   T  +  +T+ ++  + ++ T   
Sbjct: 2705 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2764

Query: 1061 TALVPPLDQTASTTIVIVPTHGDLIRTTSEATVISVRKTSMAVPSLTETPFHSLRLSTPV 1120
            T    P     +TT  + PT       T   T I+   T    P+ T T   +   +TP+
Sbjct: 2765 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT---TTPI 2821

Query: 1121 TAKAETTLFSTSVDTVTPSTH-----TLVCSKPPPDNIP-----PASSTHVISTTSTPEA 1170
            T     T   T   T TP+T      T V   P P         P ++T  ++ T TP  
Sbjct: 2822 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2881

Query: 1171 TQPISQVEETSTYALSFPYTFSGGGVVASLATGTTETSVVDETTPSHISANKLT--TSVN 1228
            TQ  +    T+T  ++ P     G    +    TT T+V    TP+       T  T+  
Sbjct: 2882 TQTPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2940

Query: 1229 SHISSSATYRVHTPVSIQLVTSTSVLSSDKDQMTISLGKTPRTMEVT---------EMSP 1279
            +   +       TP +  + T+T+V  +     T +   TP T   T           +P
Sbjct: 2941 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3000

Query: 1280 SKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSPSEIPLGTPSDGNLASSPTSGSTQI 1339
            +     + +  TP+   T T  P TT I++  T +P+  P GT +     ++P + +T +
Sbjct: 3001 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP---TTTPITTTTTV 3057

Query: 1340 TPTLTSSNTVGVHIPEMSTSLGKTALPSQALTITTFLCPEKESTSALPAYTPRTVEMIVN 1399
            TPT T + T       ++T+   T  P+   T T    P   +T+  P  TP   +    
Sbjct: 3058 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3117

Query: 1400 STYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINTTFSHLHSLRTQPEVTSVASFISEST 1459
            +   T        T+   T T + T+      I TT +   +       T   + I+ +T
Sbjct: 3118 TPITT-------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3170

Query: 1460 QTFPESLSLSTAGLYNDGFTVLSDRITTAFSVPNVPTMLPRESSMATSTPIYQMSSLPVN 1519
               P      T        T  +  ITT  +V   PT  P  +   T+TPI   +++   
Sbjct: 3171 TVTPTPTPTGTQ-------TPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPT 3221

Query: 1520 VTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPATVSS 1579
             T   ++  + TP    T  + T  P   ++P T      + ++  P      TP T   
Sbjct: 3222 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3281

Query: 1580 DTSTRVGLFSTLLSSVTPRTTMTMQTSTLDVTPVIYAGATSKNKMVSSAFTTEMIEAPSR 1639
             T+T V    T   + TP TT    T+T+  TP      T     +++  T      P+ 
Sbjct: 3282 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3341

Query: 1640 I-TPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSPL------SSKSTGAISSIP 1692
              TPTT    T  T+    T PT       TP   TT  +P        + +T  I++  
Sbjct: 3342 TQTPTTTPITTTTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3400

Query: 1693 KTTFSPFLSATQQSSQADEATTLGILSGITNRSLSTVNSGTGVALTDTYSRITVPENMLS 1752
              T +P  + TQ  +     TT  +    T     T  + T +  T T +    P    +
Sbjct: 3401 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQT 3459

Query: 1753 PTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLLEKTSLTNYAT 1812
            PT      T+    V+P+ T   + +  T  + TTT    + T   T     T +T   T
Sbjct: 3460 PTTTPITTTT---TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT--T 3514

Query: 1813 SLNTPVSYPPWTPSSATLPSLTSFVYSPHSTEAEISTPKTSPPPTSQMVEFPVLGTRMTS 1872
            +  TP   P  T +  T P  T+   +P  T     TP T+P  T+  V      T   +
Sbjct: 3515 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3574

Query: 1873 SNTQPLLMTSW--NIPTAEGSQFPISTTINVPTSNEMETETLHLVPGPLSTFTASQTGLV 1930
              T P+  T+     PT  G+Q P +T I   T       T+   P P  T T + T + 
Sbjct: 3575 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-------TVTPTPTPTGTQTPTTTPIT 3627

Query: 1931 SKDVMAMSSIPMSGILPNHGLSENPSLSTSLRAITSTLADVKHTFEKMTTSVTPGTTLPS 1990
            +   +  +  P     P          +T+    T+T+          T + TP TT  +
Sbjct: 3628 TTTTVTPTPTPTGTQTP----------TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3677

Query: 1991 ILSGAT-SGSVISKSPILTWLLSSLPSGSPPATVSNAPHVMTSSTVEVSKSTFLTSDMIS 2049
            +    T +G+    +  +T   +  P+ +P  T +     +T++T      T   +   +
Sbjct: 3678 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3737

Query: 2050 AHPFTNLTTLP---------SATMSTILTRTIPTPTLGGITTGFPTSLPMSINVTDDIVY 2100
              P T  TT+          + T + I T T  TPT     T  PT+ P++   T     
Sbjct: 3738 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3797

Query: 2101 ISTHPEASSRTTITANPRTVSHPSSFSRKTMSPSTTDHTLSVGAMPLPSSTITSSWNRIP 2160
              T  +  + T IT    T   P+     T +P+TT  T +    P P+ T T +    P
Sbjct: 3798 TPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3855

Query: 2161 TASSPSTLIIPKPT---LDSLLNIMTTTSTVPGASFPLISTGVTYPFTATVS-SPISSFF 2216
              ++ +    P PT     +   I TTT+  P  +     T  T P T T + +P  +  
Sbjct: 3856 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3915

Query: 2217 ETTWLDSTPSFLSTEASTSPTAT 2239
             T    +TP   +T  + +PT T
Sbjct: 3916 GTQTPTTTPITTTTTVTPTPTPT 3938



 Score =  348 bits (892), Expect = 6e-95
 Identities = 468/2063 (22%), Positives = 736/2063 (35%), Gaps = 157/2063 (7%)

Query: 235  TIQEKSTTVSQQIDMTTPSQITGVKPQNTAHSSTLLSQSIPIFATDYTTISYSNTTSPPL 294
            T+    T    Q   TTP   T         + T    + PI  T         TT  P 
Sbjct: 2044 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT---------TTVTPT 2094

Query: 295  ETMTAQKILKTLVDETATFAVDVLSTSSAISLPTQSISIDNTTNSMKKTKSPSSESTKTT 354
             T T  +   T    T T    V  T +     T + +   TT ++  T +P+   T TT
Sbjct: 2095 PTPTGTQTPTTTPITTTT---TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2151

Query: 355  KMVEAMATEIFQPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFSTIESTSMST 414
              +    T +   PTP+   + +     +  + T         T TT+  +T  + + + 
Sbjct: 2152 TPITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2210

Query: 415  TPCLKQKSTNTGALPISTAGQEFIESTAAGTVPWFTVEKTSPASTHVGTASSFPPEPVLI 474
            TP   Q  T T   PI+T        T  GT         +P +T + T ++  P P   
Sbjct: 2211 TPTGTQTPTTT---PITTTTTVTPTPTPTGT--------QTPTTTPITTTTTVTPTPTPT 2259

Query: 475  STAAPVDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETTPAPRTAETELTSTNFQD 534
             T  P  +      T  P  T       T   +T  T  +  TP P   +T  T+     
Sbjct: 2260 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-VTPTPTPTGTQTPTTTPITTT 2318

Query: 535  VSLPRVEDAMSTSMSKETSSKTFSFLTSFSF-TGTESVQTVIDAEATRTALTPEITLAST 593
             ++        T     T   T + +T     TGT++  T      T    TP  T   T
Sbjct: 2319 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2378

Query: 594  VAETMLSSTITGRVYTQNTPTADGHLLTLMSTRSASTSKAPESGPTSTTDEAAHLFSSNE 653
               T +++T T       TPT  G      +  + +T+  P   PT T        ++  
Sbjct: 2379 PTTTPITTTTT----VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2434

Query: 654  TIWTSRPDQALLASMNTTTILTFVPNENFTSAFHENTTYTEYLSATTNITPLKASPEGKG 713
            T+ T  P      +  TT I T        +     T  T  ++ TT +TP   +P   G
Sbjct: 2435 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTG 2490

Query: 714  TTANDATTARYTTAVSKLTSPWFANFSIVSGTTSITNMPEFKLTTLLLKTIPMSTKPANE 773
            T     T    TT V+   +P        +GT + T  P    TT+     P  T+    
Sbjct: 2491 TQTPTTTPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2542

Query: 774  LPLTPRETVVPSVDIISTLACIQPNFSTEESASET-----TQTEINGAIVFGGTTTPVP- 827
             P+T   TV P+     T        +T  + + T     TQT     I    T TP P 
Sbjct: 2543 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2602

Query: 828  ----KSATTQRLNATVT---RKEATSHYLMRKSTIAAVAEVSPFSTMLEVTDESAQRVTA 880
                ++ TT  +  T T       T       + I     V+P  T       +   +T 
Sbjct: 2603 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2662

Query: 881  SVTVSSFPDIEKLSTPLDNKTATTEVRESWLLTKLVKTTPRSSYNEMTEMFNFNHTYVAH 940
            + TV+  P      TP      TT        T     TP  +    T       T V  
Sbjct: 2663 TTTVTPTPTPTGTQTPTTTPITTTT-------TVTPTPTPTGTQTPTTTPITTTTT-VTP 2714

Query: 941  WTSETSEGISAGSPTSGSTHIFGEPLGASTTRISETSFSTTPTDRTATSLSDGILPPQPT 1000
              + T       +P + +T +   P    T   + T  +TT T  T T    G   P  T
Sbjct: 2715 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTT 2773

Query: 1001 AAHSSATPVPVTHMFSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMT 1060
               ++ T  P           ++ +   T VT +   T  +  +T+ ++  + ++ T   
Sbjct: 2774 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2833

Query: 1061 TALVPPLDQTASTTIVIVPTHGDLIRTTSEATVISVRKTSMAVPSLTETPFHSLRLSTPV 1120
            T    P     +TT  + PT       T   T I+   T    P+ T T   +   +TP+
Sbjct: 2834 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT---TTPI 2890

Query: 1121 TAKAETTLFSTSVDTVTPSTH-----TLVCSKPPPDNIP-----PASSTHVISTTSTPEA 1170
            T     T   T   T TP+T      T V   P P         P ++T  ++ T TP  
Sbjct: 2891 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2950

Query: 1171 TQPISQVEETSTYALSFPYTFSGGGVVASLATGTTETSVVDETTPSHISANKLT--TSVN 1228
            TQ  +    T+T  ++ P     G    +    TT T+V    TP+       T  T+  
Sbjct: 2951 TQTPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3009

Query: 1229 SHISSSATYRVHTPVSIQLVTSTSVLSSDKDQMTISLGKTPRTMEVT---------EMSP 1279
            +   +       TP +  + T+T+V  +     T +   TP T   T           +P
Sbjct: 3010 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3069

Query: 1280 SKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSPSEIPLGTPSDGNLASSPTSGSTQI 1339
            +     + +  TP+   T T  P TT I++  T +P+  P GT +     ++P + +T +
Sbjct: 3070 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP---TTTPITTTTTV 3126

Query: 1340 TPTLTSSNTVGVHIPEMSTSLGKTALPSQALTITTFLCPEKESTSALPAYTPRTVEMIVN 1399
            TPT T + T       ++T+   T  P+   T T    P   +T+  P  TP   +    
Sbjct: 3127 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3186

Query: 1400 STYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINTTFSHLHSLRTQPEVTSVASFISEST 1459
            +   T        T+   T T + T+      I TT +   +       T   + I+ +T
Sbjct: 3187 TPITT-------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3239

Query: 1460 QTFPESLSLSTAGLYNDGFTVLSDRITTAFSVPNVPTMLPRESSMATSTPIYQMSSLPVN 1519
               P      T        T  +  ITT  +V   PT  P  +   T+TPI   +++   
Sbjct: 3240 TVTPTPTPTGTQ-------TPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPT 3290

Query: 1520 VTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPATVSS 1579
             T   ++  + TP    T  + T  P   ++P T      + ++  P      TP T   
Sbjct: 3291 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3350

Query: 1580 DTSTRVGLFSTLLSSVTPRTTMTMQTSTLDVTPVIYAGATSKNKMVSSAFTTEMIEAPSR 1639
             T+T V    T   + TP TT    T+T+  TP      T     +++  T      P+ 
Sbjct: 3351 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3410

Query: 1640 I-TPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSPL------SSKSTGAISSIP 1692
              TPTT    T  T+    T PT       TP   TT  +P        + +T  I++  
Sbjct: 3411 TQTPTTTPITTTTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3469

Query: 1693 KTTFSPFLSATQQSSQADEATTLGILSGITNRSLSTVNSGTGVALTDTYSRITVPENMLS 1752
              T +P  + TQ  +     TT  +    T     T  + T +  T T +    P    +
Sbjct: 3470 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQT 3528

Query: 1753 PTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLLEKTSLTNYAT 1812
            PT      T+    V+P+ T   + +  T  + TTT    + T   T     T +T   T
Sbjct: 3529 PTTTPITTTT---TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT--T 3583

Query: 1813 SLNTPVSYPPWTPSSATLPSLTSFVYSPHSTEAEISTPKTSPPPTSQMVEFPVLGTRMTS 1872
            +  TP   P  T +  T P  T+   +P  T     TP T+P  T+  V      T   +
Sbjct: 3584 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3643

Query: 1873 SNTQPLLMTSW--NIPTAEGSQFPISTTINVPTSNEMETETLHLVPGPLSTFTASQTGLV 1930
              T P+  T+     PT  G+Q P +T I   T       T+   P P  T T + T + 
Sbjct: 3644 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-------TVTPTPTPTGTQTPTTTPIT 3696

Query: 1931 SKDVMAMSSIPMSGILPNHGLSENPSLSTSLRAITSTLADVKHTFEKMTTSVTPGTTLPS 1990
            +   +  +  P     P          +T+    T+T+          T + TP TT  +
Sbjct: 3697 TTTTVTPTPTPTGTQTP----------TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3746

Query: 1991 ILSGAT-SGSVISKSPILTWLLSSLPSGSPPATVSNAPHVMTSSTVEVSKSTFLTSDMIS 2049
            +    T +G+    +  +T   +  P+ +P  T +     +T++T      T   +   +
Sbjct: 3747 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3806

Query: 2050 AHPFTNLTTLP---------SATMSTILTRTIPTPTLGGITTGFPTSLPMSINVTDDIVY 2100
              P T  TT+          + T + I T T  TPT     T  PT+ P++   T     
Sbjct: 3807 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3866

Query: 2101 ISTHPEASSRTTITANPRTVSHPSSFSRKTMSPSTTDHTLSVGAMPLPSSTITSSWNRIP 2160
              T  +  + T IT    T   P+     T +P+TT  T +    P P+ T T +    P
Sbjct: 3867 TPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3924

Query: 2161 TASSPSTLIIPKPT---LDSLLNIMTTTSTVPGASFPLISTGVTYPFTATVS-SPISSFF 2216
              ++ +    P PT     +   I TTT+  P  +     T  T P T T + +P  +  
Sbjct: 3925 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3984

Query: 2217 ETTWLDSTPSFLSTEASTSPTAT 2239
             T    +TP   +T  + +PT T
Sbjct: 3985 GTQTPTTTPITTTTTVTPTPTPT 4007



 Score =  348 bits (892), Expect = 6e-95
 Identities = 468/2063 (22%), Positives = 736/2063 (35%), Gaps = 157/2063 (7%)

Query: 235  TIQEKSTTVSQQIDMTTPSQITGVKPQNTAHSSTLLSQSIPIFATDYTTISYSNTTSPPL 294
            T+    T    Q   TTP   T         + T    + PI  T         TT  P 
Sbjct: 2113 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT---------TTVTPT 2163

Query: 295  ETMTAQKILKTLVDETATFAVDVLSTSSAISLPTQSISIDNTTNSMKKTKSPSSESTKTT 354
             T T  +   T    T T    V  T +     T + +   TT ++  T +P+   T TT
Sbjct: 2164 PTPTGTQTPTTTPITTTT---TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2220

Query: 355  KMVEAMATEIFQPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFSTIESTSMST 414
              +    T +   PTP+   + +     +  + T         T TT+  +T  + + + 
Sbjct: 2221 TPITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2279

Query: 415  TPCLKQKSTNTGALPISTAGQEFIESTAAGTVPWFTVEKTSPASTHVGTASSFPPEPVLI 474
            TP   Q  T T   PI+T        T  GT         +P +T + T ++  P P   
Sbjct: 2280 TPTGTQTPTTT---PITTTTTVTPTPTPTGT--------QTPTTTPITTTTTVTPTPTPT 2328

Query: 475  STAAPVDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETTPAPRTAETELTSTNFQD 534
             T  P  +      T  P  T       T   +T  T  +  TP P   +T  T+     
Sbjct: 2329 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-VTPTPTPTGTQTPTTTPITTT 2387

Query: 535  VSLPRVEDAMSTSMSKETSSKTFSFLTSFSF-TGTESVQTVIDAEATRTALTPEITLAST 593
             ++        T     T   T + +T     TGT++  T      T    TP  T   T
Sbjct: 2388 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2447

Query: 594  VAETMLSSTITGRVYTQNTPTADGHLLTLMSTRSASTSKAPESGPTSTTDEAAHLFSSNE 653
               T +++T T       TPT  G      +  + +T+  P   PT T        ++  
Sbjct: 2448 PTTTPITTTTT----VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2503

Query: 654  TIWTSRPDQALLASMNTTTILTFVPNENFTSAFHENTTYTEYLSATTNITPLKASPEGKG 713
            T+ T  P      +  TT I T        +     T  T  ++ TT +TP   +P   G
Sbjct: 2504 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTG 2559

Query: 714  TTANDATTARYTTAVSKLTSPWFANFSIVSGTTSITNMPEFKLTTLLLKTIPMSTKPANE 773
            T     T    TT V+   +P        +GT + T  P    TT+     P  T+    
Sbjct: 2560 TQTPTTTPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2611

Query: 774  LPLTPRETVVPSVDIISTLACIQPNFSTEESASET-----TQTEINGAIVFGGTTTPVP- 827
             P+T   TV P+     T        +T  + + T     TQT     I    T TP P 
Sbjct: 2612 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2671

Query: 828  ----KSATTQRLNATVT---RKEATSHYLMRKSTIAAVAEVSPFSTMLEVTDESAQRVTA 880
                ++ TT  +  T T       T       + I     V+P  T       +   +T 
Sbjct: 2672 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2731

Query: 881  SVTVSSFPDIEKLSTPLDNKTATTEVRESWLLTKLVKTTPRSSYNEMTEMFNFNHTYVAH 940
            + TV+  P      TP      TT        T     TP  +    T       T V  
Sbjct: 2732 TTTVTPTPTPTGTQTPTTTPITTTT-------TVTPTPTPTGTQTPTTTPITTTTT-VTP 2783

Query: 941  WTSETSEGISAGSPTSGSTHIFGEPLGASTTRISETSFSTTPTDRTATSLSDGILPPQPT 1000
              + T       +P + +T +   P    T   + T  +TT T  T T    G   P  T
Sbjct: 2784 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTT 2842

Query: 1001 AAHSSATPVPVTHMFSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMT 1060
               ++ T  P           ++ +   T VT +   T  +  +T+ ++  + ++ T   
Sbjct: 2843 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2902

Query: 1061 TALVPPLDQTASTTIVIVPTHGDLIRTTSEATVISVRKTSMAVPSLTETPFHSLRLSTPV 1120
            T    P     +TT  + PT       T   T I+   T    P+ T T   +   +TP+
Sbjct: 2903 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT---TTPI 2959

Query: 1121 TAKAETTLFSTSVDTVTPSTH-----TLVCSKPPPDNIP-----PASSTHVISTTSTPEA 1170
            T     T   T   T TP+T      T V   P P         P ++T  ++ T TP  
Sbjct: 2960 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3019

Query: 1171 TQPISQVEETSTYALSFPYTFSGGGVVASLATGTTETSVVDETTPSHISANKLT--TSVN 1228
            TQ  +    T+T  ++ P     G    +    TT T+V    TP+       T  T+  
Sbjct: 3020 TQTPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3078

Query: 1229 SHISSSATYRVHTPVSIQLVTSTSVLSSDKDQMTISLGKTPRTMEVT---------EMSP 1279
            +   +       TP +  + T+T+V  +     T +   TP T   T           +P
Sbjct: 3079 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3138

Query: 1280 SKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSPSEIPLGTPSDGNLASSPTSGSTQI 1339
            +     + +  TP+   T T  P TT I++  T +P+  P GT +     ++P + +T +
Sbjct: 3139 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP---TTTPITTTTTV 3195

Query: 1340 TPTLTSSNTVGVHIPEMSTSLGKTALPSQALTITTFLCPEKESTSALPAYTPRTVEMIVN 1399
            TPT T + T       ++T+   T  P+   T T    P   +T+  P  TP   +    
Sbjct: 3196 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3255

Query: 1400 STYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINTTFSHLHSLRTQPEVTSVASFISEST 1459
            +   T        T+   T T + T+      I TT +   +       T   + I+ +T
Sbjct: 3256 TPITT-------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3308

Query: 1460 QTFPESLSLSTAGLYNDGFTVLSDRITTAFSVPNVPTMLPRESSMATSTPIYQMSSLPVN 1519
               P      T        T  +  ITT  +V   PT  P  +   T+TPI   +++   
Sbjct: 3309 TVTPTPTPTGTQ-------TPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPT 3359

Query: 1520 VTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPATVSS 1579
             T   ++  + TP    T  + T  P   ++P T      + ++  P      TP T   
Sbjct: 3360 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3419

Query: 1580 DTSTRVGLFSTLLSSVTPRTTMTMQTSTLDVTPVIYAGATSKNKMVSSAFTTEMIEAPSR 1639
             T+T V    T   + TP TT    T+T+  TP      T     +++  T      P+ 
Sbjct: 3420 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3479

Query: 1640 I-TPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSPL------SSKSTGAISSIP 1692
              TPTT    T  T+    T PT       TP   TT  +P        + +T  I++  
Sbjct: 3480 TQTPTTTPITTTTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3538

Query: 1693 KTTFSPFLSATQQSSQADEATTLGILSGITNRSLSTVNSGTGVALTDTYSRITVPENMLS 1752
              T +P  + TQ  +     TT  +    T     T  + T +  T T +    P    +
Sbjct: 3539 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQT 3597

Query: 1753 PTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLLEKTSLTNYAT 1812
            PT      T+    V+P+ T   + +  T  + TTT    + T   T     T +T   T
Sbjct: 3598 PTTTPITTTT---TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT--T 3652

Query: 1813 SLNTPVSYPPWTPSSATLPSLTSFVYSPHSTEAEISTPKTSPPPTSQMVEFPVLGTRMTS 1872
            +  TP   P  T +  T P  T+   +P  T     TP T+P  T+  V      T   +
Sbjct: 3653 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3712

Query: 1873 SNTQPLLMTSW--NIPTAEGSQFPISTTINVPTSNEMETETLHLVPGPLSTFTASQTGLV 1930
              T P+  T+     PT  G+Q P +T I   T       T+   P P  T T + T + 
Sbjct: 3713 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-------TVTPTPTPTGTQTPTTTPIT 3765

Query: 1931 SKDVMAMSSIPMSGILPNHGLSENPSLSTSLRAITSTLADVKHTFEKMTTSVTPGTTLPS 1990
            +   +  +  P     P          +T+    T+T+          T + TP TT  +
Sbjct: 3766 TTTTVTPTPTPTGTQTP----------TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3815

Query: 1991 ILSGAT-SGSVISKSPILTWLLSSLPSGSPPATVSNAPHVMTSSTVEVSKSTFLTSDMIS 2049
            +    T +G+    +  +T   +  P+ +P  T +     +T++T      T   +   +
Sbjct: 3816 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3875

Query: 2050 AHPFTNLTTLP---------SATMSTILTRTIPTPTLGGITTGFPTSLPMSINVTDDIVY 2100
              P T  TT+          + T + I T T  TPT     T  PT+ P++   T     
Sbjct: 3876 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3935

Query: 2101 ISTHPEASSRTTITANPRTVSHPSSFSRKTMSPSTTDHTLSVGAMPLPSSTITSSWNRIP 2160
              T  +  + T IT    T   P+     T +P+TT  T +    P P+ T T +    P
Sbjct: 3936 TPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3993

Query: 2161 TASSPSTLIIPKPT---LDSLLNIMTTTSTVPGASFPLISTGVTYPFTATVS-SPISSFF 2216
              ++ +    P PT     +   I TTT+  P  +     T  T P T T + +P  +  
Sbjct: 3994 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4053

Query: 2217 ETTWLDSTPSFLSTEASTSPTAT 2239
             T    +TP   +T  + +PT T
Sbjct: 4054 GTQTPTTTPITTTTTVTPTPTPT 4076



 Score =  348 bits (892), Expect = 6e-95
 Identities = 468/2063 (22%), Positives = 736/2063 (35%), Gaps = 157/2063 (7%)

Query: 235  TIQEKSTTVSQQIDMTTPSQITGVKPQNTAHSSTLLSQSIPIFATDYTTISYSNTTSPPL 294
            T+    T    Q   TTP   T         + T    + PI  T         TT  P 
Sbjct: 2182 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT---------TTVTPT 2232

Query: 295  ETMTAQKILKTLVDETATFAVDVLSTSSAISLPTQSISIDNTTNSMKKTKSPSSESTKTT 354
             T T  +   T    T T    V  T +     T + +   TT ++  T +P+   T TT
Sbjct: 2233 PTPTGTQTPTTTPITTTT---TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2289

Query: 355  KMVEAMATEIFQPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFSTIESTSMST 414
              +    T +   PTP+   + +     +  + T         T TT+  +T  + + + 
Sbjct: 2290 TPITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2348

Query: 415  TPCLKQKSTNTGALPISTAGQEFIESTAAGTVPWFTVEKTSPASTHVGTASSFPPEPVLI 474
            TP   Q  T T   PI+T        T  GT         +P +T + T ++  P P   
Sbjct: 2349 TPTGTQTPTTT---PITTTTTVTPTPTPTGT--------QTPTTTPITTTTTVTPTPTPT 2397

Query: 475  STAAPVDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETTPAPRTAETELTSTNFQD 534
             T  P  +      T  P  T       T   +T  T  +  TP P   +T  T+     
Sbjct: 2398 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-VTPTPTPTGTQTPTTTPITTT 2456

Query: 535  VSLPRVEDAMSTSMSKETSSKTFSFLTSFSF-TGTESVQTVIDAEATRTALTPEITLAST 593
             ++        T     T   T + +T     TGT++  T      T    TP  T   T
Sbjct: 2457 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2516

Query: 594  VAETMLSSTITGRVYTQNTPTADGHLLTLMSTRSASTSKAPESGPTSTTDEAAHLFSSNE 653
               T +++T T       TPT  G      +  + +T+  P   PT T        ++  
Sbjct: 2517 PTTTPITTTTT----VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2572

Query: 654  TIWTSRPDQALLASMNTTTILTFVPNENFTSAFHENTTYTEYLSATTNITPLKASPEGKG 713
            T+ T  P      +  TT I T        +     T  T  ++ TT +TP   +P   G
Sbjct: 2573 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTG 2628

Query: 714  TTANDATTARYTTAVSKLTSPWFANFSIVSGTTSITNMPEFKLTTLLLKTIPMSTKPANE 773
            T     T    TT V+   +P        +GT + T  P    TT+     P  T+    
Sbjct: 2629 TQTPTTTPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2680

Query: 774  LPLTPRETVVPSVDIISTLACIQPNFSTEESASET-----TQTEINGAIVFGGTTTPVP- 827
             P+T   TV P+     T        +T  + + T     TQT     I    T TP P 
Sbjct: 2681 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2740

Query: 828  ----KSATTQRLNATVT---RKEATSHYLMRKSTIAAVAEVSPFSTMLEVTDESAQRVTA 880
                ++ TT  +  T T       T       + I     V+P  T       +   +T 
Sbjct: 2741 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2800

Query: 881  SVTVSSFPDIEKLSTPLDNKTATTEVRESWLLTKLVKTTPRSSYNEMTEMFNFNHTYVAH 940
            + TV+  P      TP      TT        T     TP  +    T       T V  
Sbjct: 2801 TTTVTPTPTPTGTQTPTTTPITTTT-------TVTPTPTPTGTQTPTTTPITTTTT-VTP 2852

Query: 941  WTSETSEGISAGSPTSGSTHIFGEPLGASTTRISETSFSTTPTDRTATSLSDGILPPQPT 1000
              + T       +P + +T +   P    T   + T  +TT T  T T    G   P  T
Sbjct: 2853 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTT 2911

Query: 1001 AAHSSATPVPVTHMFSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMT 1060
               ++ T  P           ++ +   T VT +   T  +  +T+ ++  + ++ T   
Sbjct: 2912 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2971

Query: 1061 TALVPPLDQTASTTIVIVPTHGDLIRTTSEATVISVRKTSMAVPSLTETPFHSLRLSTPV 1120
            T    P     +TT  + PT       T   T I+   T    P+ T T   +   +TP+
Sbjct: 2972 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT---TTPI 3028

Query: 1121 TAKAETTLFSTSVDTVTPSTH-----TLVCSKPPPDNIP-----PASSTHVISTTSTPEA 1170
            T     T   T   T TP+T      T V   P P         P ++T  ++ T TP  
Sbjct: 3029 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3088

Query: 1171 TQPISQVEETSTYALSFPYTFSGGGVVASLATGTTETSVVDETTPSHISANKLT--TSVN 1228
            TQ  +    T+T  ++ P     G    +    TT T+V    TP+       T  T+  
Sbjct: 3089 TQTPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3147

Query: 1229 SHISSSATYRVHTPVSIQLVTSTSVLSSDKDQMTISLGKTPRTMEVT---------EMSP 1279
            +   +       TP +  + T+T+V  +     T +   TP T   T           +P
Sbjct: 3148 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3207

Query: 1280 SKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSPSEIPLGTPSDGNLASSPTSGSTQI 1339
            +     + +  TP+   T T  P TT I++  T +P+  P GT +     ++P + +T +
Sbjct: 3208 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP---TTTPITTTTTV 3264

Query: 1340 TPTLTSSNTVGVHIPEMSTSLGKTALPSQALTITTFLCPEKESTSALPAYTPRTVEMIVN 1399
            TPT T + T       ++T+   T  P+   T T    P   +T+  P  TP   +    
Sbjct: 3265 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3324

Query: 1400 STYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINTTFSHLHSLRTQPEVTSVASFISEST 1459
            +   T        T+   T T + T+      I TT +   +       T   + I+ +T
Sbjct: 3325 TPITT-------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3377

Query: 1460 QTFPESLSLSTAGLYNDGFTVLSDRITTAFSVPNVPTMLPRESSMATSTPIYQMSSLPVN 1519
               P      T        T  +  ITT  +V   PT  P  +   T+TPI   +++   
Sbjct: 3378 TVTPTPTPTGTQ-------TPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPT 3428

Query: 1520 VTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPATVSS 1579
             T   ++  + TP    T  + T  P   ++P T      + ++  P      TP T   
Sbjct: 3429 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3488

Query: 1580 DTSTRVGLFSTLLSSVTPRTTMTMQTSTLDVTPVIYAGATSKNKMVSSAFTTEMIEAPSR 1639
             T+T V    T   + TP TT    T+T+  TP      T     +++  T      P+ 
Sbjct: 3489 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3548

Query: 1640 I-TPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSPL------SSKSTGAISSIP 1692
              TPTT    T  T+    T PT       TP   TT  +P        + +T  I++  
Sbjct: 3549 TQTPTTTPITTTTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3607

Query: 1693 KTTFSPFLSATQQSSQADEATTLGILSGITNRSLSTVNSGTGVALTDTYSRITVPENMLS 1752
              T +P  + TQ  +     TT  +    T     T  + T +  T T +    P    +
Sbjct: 3608 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQT 3666

Query: 1753 PTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLLEKTSLTNYAT 1812
            PT      T+    V+P+ T   + +  T  + TTT    + T   T     T +T   T
Sbjct: 3667 PTTTPITTTT---TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT--T 3721

Query: 1813 SLNTPVSYPPWTPSSATLPSLTSFVYSPHSTEAEISTPKTSPPPTSQMVEFPVLGTRMTS 1872
            +  TP   P  T +  T P  T+   +P  T     TP T+P  T+  V      T   +
Sbjct: 3722 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3781

Query: 1873 SNTQPLLMTSW--NIPTAEGSQFPISTTINVPTSNEMETETLHLVPGPLSTFTASQTGLV 1930
              T P+  T+     PT  G+Q P +T I   T       T+   P P  T T + T + 
Sbjct: 3782 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-------TVTPTPTPTGTQTPTTTPIT 3834

Query: 1931 SKDVMAMSSIPMSGILPNHGLSENPSLSTSLRAITSTLADVKHTFEKMTTSVTPGTTLPS 1990
            +   +  +  P     P          +T+    T+T+          T + TP TT  +
Sbjct: 3835 TTTTVTPTPTPTGTQTP----------TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3884

Query: 1991 ILSGAT-SGSVISKSPILTWLLSSLPSGSPPATVSNAPHVMTSSTVEVSKSTFLTSDMIS 2049
            +    T +G+    +  +T   +  P+ +P  T +     +T++T      T   +   +
Sbjct: 3885 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3944

Query: 2050 AHPFTNLTTLP---------SATMSTILTRTIPTPTLGGITTGFPTSLPMSINVTDDIVY 2100
              P T  TT+          + T + I T T  TPT     T  PT+ P++   T     
Sbjct: 3945 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 4004

Query: 2101 ISTHPEASSRTTITANPRTVSHPSSFSRKTMSPSTTDHTLSVGAMPLPSSTITSSWNRIP 2160
              T  +  + T IT    T   P+     T +P+TT  T +    P P+ T T +    P
Sbjct: 4005 TPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4062

Query: 2161 TASSPSTLIIPKPT---LDSLLNIMTTTSTVPGASFPLISTGVTYPFTATVS-SPISSFF 2216
              ++ +    P PT     +   I TTT+  P  +     T  T P T T + +P  +  
Sbjct: 4063 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4122

Query: 2217 ETTWLDSTPSFLSTEASTSPTAT 2239
             T    +TP   +T  + +PT T
Sbjct: 4123 GTQTPTTTPITTTTTVTPTPTPT 4145



 Score =  344 bits (882), Expect = 9e-94
 Identities = 468/2065 (22%), Positives = 734/2065 (35%), Gaps = 161/2065 (7%)

Query: 235  TIQEKSTTVSQQIDMTTPSQITGVKPQNTAHSSTLLSQSIPIFATDYTTISYSNTTSPPL 294
            T+    T    Q   TTP   T         + T    + PI  T         TT  P 
Sbjct: 2251 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT---------TTVTPT 2301

Query: 295  ETMTAQKILKTLVDETATFAVDVLSTSSAISLPTQSISIDNTTNSMKKTKSPSSESTKTT 354
             T T  +   T    T T    V  T +     T + +   TT ++  T +P+   T TT
Sbjct: 2302 PTPTGTQTPTTTPITTTT---TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2358

Query: 355  KMVEAMATEIFQPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFSTIESTSMST 414
              +    T +   PTP+   + +     +  + T         T TT+  +T  + + + 
Sbjct: 2359 TPITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2417

Query: 415  TPCLKQKSTNTGALPISTAGQEFIESTAAGTVPWFTVEKTSPASTHVGTASSFPPEPVLI 474
            TP   Q  T T   PI+T        T  GT         +P +T + T ++  P P   
Sbjct: 2418 TPTGTQTPTTT---PITTTTTVTPTPTPTGT--------QTPTTTPITTTTTVTPTPTPT 2466

Query: 475  STAAPVDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETTPAPRTAETELTSTNFQD 534
             T  P  +      T  P  T       T   +T  T  +  TP P   +T  T+     
Sbjct: 2467 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-VTPTPTPTGTQTPTTTPITTT 2525

Query: 535  VSLPRVEDAMSTSMSKETSSKTFSFLTSFSF-TGTESVQTVIDAEATRTALTPEITLAST 593
             ++        T     T   T + +T     TGT++  T      T    TP  T   T
Sbjct: 2526 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2585

Query: 594  VAETMLSSTITGRVYTQNTPTADGHLLTLMSTRSASTSKAPESGPTSTTDEAAHLFSSNE 653
               T +++T T       TPT  G      +  + +T+  P   PT T        ++  
Sbjct: 2586 PTTTPITTTTT----VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2641

Query: 654  TIWTSRPDQALLASMNTTTILTFVPNENFTSAFHENTTYTEYLSATTNITPLKASPEGKG 713
            T+ T  P      +  TT I T        +     T  T  ++ TT +TP   +P   G
Sbjct: 2642 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTG 2697

Query: 714  TTANDATTARYTTAVSKLTSPWFANFSIVSGTTSITNMPEFKLTTLLLKTIPMSTKPANE 773
            T     T    TT V+   +P        +GT + T  P    TT+     P  T+    
Sbjct: 2698 TQTPTTTPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2749

Query: 774  LPLTPRETVVPSVDIISTLACIQPNFSTEESASET-----TQTEINGAIVFGGTTTPVP- 827
             P+T   TV P+     T        +T  + + T     TQT     I    T TP P 
Sbjct: 2750 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2809

Query: 828  ----KSATTQRLNATVT---RKEATSHYLMRKSTIAAVAEVSPFSTMLEVTDESAQRVTA 880
                ++ TT  +  T T       T       + I     V+P  T       +   +T 
Sbjct: 2810 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2869

Query: 881  SVTVSSFPDIEKLSTPLDNKTATTEVRESWLLTKLVKTTPRSSYNEMTEMFNFNHTYVAH 940
            + TV+  P      TP      TT        T     TP  +    T       T V  
Sbjct: 2870 TTTVTPTPTPTGTQTPTTTPITTTT-------TVTPTPTPTGTQTPTTTPITTTTT-VTP 2921

Query: 941  WTSETSEGISAGSPTSGSTHIFGEPLGASTTRISETSFSTTPTDRTATSLSDGILPPQPT 1000
              + T       +P + +T +   P    T   + T  +TT T  T T    G   P  T
Sbjct: 2922 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTT 2980

Query: 1001 AAHSSATPVPVTHMFSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMT 1060
               ++ T  P           ++ +   T VT +   T  +  +T+ ++  + ++ T   
Sbjct: 2981 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3040

Query: 1061 TALVPPLDQTASTTIVIVPTHGDLIRTTSEATVISVRKTSMAVPSLTETPFHSLRLSTPV 1120
            T    P     +TT  + PT       T   T I+   T    P+ T T   +   +TP+
Sbjct: 3041 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT---TTPI 3097

Query: 1121 TAKAETTLFSTSVDTVTPSTH-----TLVCSKPPPDNIP-----PASSTHVISTTSTPEA 1170
            T     T   T   T TP+T      T V   P P         P ++T  ++ T TP  
Sbjct: 3098 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3157

Query: 1171 TQPISQVEETSTYALSFPYTFSGGGVVASLATGTTETSVVDETTPSHISANKLT--TSVN 1228
            TQ  +    T+T  ++ P     G    +    TT T+V    TP+       T  T+  
Sbjct: 3158 TQTPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3216

Query: 1229 SHISSSATYRVHTPVSIQLVTSTSVLSSDKDQMTISLGKTPRTMEVT---------EMSP 1279
            +   +       TP +  + T+T+V  +     T +   TP T   T           +P
Sbjct: 3217 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3276

Query: 1280 SKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSPSEIPLGTPSDGNLASSPTSGSTQI 1339
            +     + +  TP+   T T  P TT I++  T +P+  P GT +     ++P + +T +
Sbjct: 3277 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP---TTTPITTTTTV 3333

Query: 1340 TPTLTSSNTVGVHIPEMSTSLGKTALPSQALTITTFLCPEKESTSALPAYTPRTVEMIVN 1399
            TPT T + T       ++T+   T  P+   T T    P   +T+  P  TP   +    
Sbjct: 3334 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3393

Query: 1400 STYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINTTFSHLHSLRTQPEVTSVASFISEST 1459
            +   T        T+   T T + T+      I TT +   +       T   + I+ +T
Sbjct: 3394 TPITT-------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3446

Query: 1460 QTFPESLSLSTAGLYNDGFTVLSDRITTAFSVPNVPTMLPRESSMATSTPIYQMSSLPVN 1519
               P      T        T  +  ITT  +V   PT  P  +   T+TPI   +++   
Sbjct: 3447 TVTPTPTPTGTQ-------TPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPT 3497

Query: 1520 VTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPATVSS 1579
             T   ++  + TP    T  + T  P   ++P T      + ++  P      TP T   
Sbjct: 3498 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3557

Query: 1580 DTSTRVGLFSTLLSSVTPRTTMTMQTSTLDVTPVIYAGATSKNKMVSSAFTTEMIEAPSR 1639
             T+T V    T   + TP TT    T+T+  TP      T     +++  T      P+ 
Sbjct: 3558 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3617

Query: 1640 I-TPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSPL------SSKSTGAISSIP 1692
              TPTT    T  T+    T PT       TP   TT  +P        + +T  I++  
Sbjct: 3618 TQTPTTTPITTTTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3676

Query: 1693 KTTFSPFLSATQQSSQADEATTLGILSGITNRSLSTVNSGTGVALTDTYSRITVPENMLS 1752
              T +P  + TQ  +     TT  +    T     T  + T +  T T +    P    +
Sbjct: 3677 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQT 3735

Query: 1753 PTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLLEKTSLTNYAT 1812
            PT      T+    V+P+ T   + +  T  + TTT    + T   T     T +T   T
Sbjct: 3736 PTTTPITTTT---TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT--T 3790

Query: 1813 SLNTPVSYPPWTPSSATLPSLTSFVYSPHSTEAEISTPKTSPPPTSQMVEFPVLGTRMTS 1872
            +  TP   P  T +  T P  T+   +P  T     TP T+P  T+  V      T   +
Sbjct: 3791 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3850

Query: 1873 SNTQPLLMTSW--NIPTAEGSQFPISTTINVPTSNEMETETLHLVPGPLSTFTASQTGLV 1930
              T P+  T+     PT  G+Q P +T I   T       T+   P P  T T + T + 
Sbjct: 3851 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-------TVTPTPTPTGTQTPTTTPIT 3903

Query: 1931 SKDVMAMSSIPMSGILPNHGLSENPSLSTSLRAITSTLADVKHTFEKMTTSVTPGTTLPS 1990
            +   +  +  P     P          +T+    T+T+          T + TP TT  +
Sbjct: 3904 TTTTVTPTPTPTGTQTP----------TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3953

Query: 1991 ILSGAT-SGSVISKSPILTWLLSSLPSGSPPATVSNAPHVMTSSTVEVSKSTFLTSDMIS 2049
            +    T +G+    +  +T   +  P+ +P  T +     +T++T      T   +   +
Sbjct: 3954 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 4013

Query: 2050 AHPFTNLTTLP---------SATMSTILTRTIPTPTLGGITTGFPTSLPMSINVTDDIVY 2100
              P T  TT+          + T + I T T  TPT     T  PT+ P++   T     
Sbjct: 4014 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 4073

Query: 2101 ISTHPEASSRTTITANPRTVSHPSSFSRKTMSPSTTDHTLSVGAMPLPSSTITSSWNRIP 2160
              T  +  + T IT    T   P+     T +P+TT  T +    P P+ T T +    P
Sbjct: 4074 TPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4131

Query: 2161 TASSPSTLIIPKPT---LDSLLNIMTTTSTVPGASFPLISTGVTYPFTATVSSPISSFFE 2217
              ++ +    P PT     +   I TTT+  P  +     T  T P T T     ++   
Sbjct: 4132 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-----TTVTP 4186

Query: 2218 TTWLDSTPSFLSTEASTSPTATKST 2242
            T     T +   T  ST+P A  +T
Sbjct: 4187 TPTPTGTQTGPPTHTSTAPIAELTT 4211



 Score =  342 bits (876), Expect = 4e-93
 Identities = 482/2099 (22%), Positives = 742/2099 (35%), Gaps = 185/2099 (8%)

Query: 235  TIQEKSTTVSQQIDMTTPSQITGVKPQNTAHSSTLLSQSIPIFATDYTTISYSNTTSPPL 294
            T+    T    Q   TTP   T         + T    + PI  T         TT  P 
Sbjct: 2389 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT---------TTVTPT 2439

Query: 295  ETMTAQKILKTLVDETATFAVDVLSTSSAISLPTQSISIDNTTNSMKKTKSPSSESTKTT 354
             T T  +   T    T T    V  T +     T + +   TT ++  T +P+   T TT
Sbjct: 2440 PTPTGTQTPTTTPITTTT---TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2496

Query: 355  KMVEAMATEIFQPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFSTIESTSMST 414
              +    T +   PTP+   + +     +  + T         T TT+  +T  + + + 
Sbjct: 2497 TPITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2555

Query: 415  TPCLKQKSTNTGALPISTAGQEFIESTAAGTVPWFTVEKTSPASTHVGTASSFPPEPVLI 474
            TP   Q  T T   PI+T        T  GT         +P +T + T ++  P P   
Sbjct: 2556 TPTGTQTPTTT---PITTTTTVTPTPTPTGT--------QTPTTTPITTTTTVTPTPTPT 2604

Query: 475  STAAPVDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETTPAPRTAETELTSTNFQD 534
             T  P  +      T  P  T       T   +T  T  +  TP P   +T  T+     
Sbjct: 2605 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-VTPTPTPTGTQTPTTTPITTT 2663

Query: 535  VSLPRVEDAMSTSMSKETSSKTFSFLTSFSF-TGTESVQTVIDAEATRTALTPEITLAST 593
             ++        T     T   T + +T     TGT++  T      T    TP  T   T
Sbjct: 2664 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2723

Query: 594  VAETMLSSTITGRVYTQNTPTADGHLLTLMSTRSASTSKAPESGPTSTTDEAAHLFSSNE 653
               T +++T T       TPT  G      +  + +T+  P   PT T        ++  
Sbjct: 2724 PTTTPITTTTT----VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2779

Query: 654  TIWTSRPDQALLASMNTTTILTFVPNENFTSAFHENTTYTEYLSATTNITPLKASPEGKG 713
            T+ T  P      +  TT I T        +     T  T  ++ TT +TP   +P   G
Sbjct: 2780 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTG 2835

Query: 714  TTANDATTARYTTAVSKLTSPWFANFSIVSGTTSITNMPEFKLTTLLLKTIPMSTKPANE 773
            T     T    TT V+   +P        +GT + T  P    TT+     P  T+    
Sbjct: 2836 TQTPTTTPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2887

Query: 774  LPLTPRETVVPSVDIISTLACIQPNFSTEESASET-----TQTEINGAIVFGGTTTPVP- 827
             P+T   TV P+     T        +T  + + T     TQT     I    T TP P 
Sbjct: 2888 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2947

Query: 828  ----KSATTQRLNATVT---RKEATSHYLMRKSTIAAVAEVSPFSTMLEVTDESAQRVTA 880
                ++ TT  +  T T       T       + I     V+P  T       +   +T 
Sbjct: 2948 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3007

Query: 881  SVTVSSFPDIEKLSTPLDNKTATTEVRESWLLTKLVKTTPRSSYNEMTEMFNFNHTYVAH 940
            + TV+  P      TP      TT        T     TP  +    T       T V  
Sbjct: 3008 TTTVTPTPTPTGTQTPTTTPITTTT-------TVTPTPTPTGTQTPTTTPITTTTT-VTP 3059

Query: 941  WTSETSEGISAGSPTSGSTHIFGEPLGASTTRISETSFSTTPTDRTATSLSDGILPPQPT 1000
              + T       +P + +T +   P    T   + T  +TT T  T T    G   P  T
Sbjct: 3060 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTT 3118

Query: 1001 AAHSSATPVPVTHMFSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMT 1060
               ++ T  P           ++ +   T VT +   T  +  +T+ ++  + ++ T   
Sbjct: 3119 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3178

Query: 1061 TALVPPLDQTASTTIVIVPTHGDLIRTTSEATVISVRKTSMAVPSLTETPFHSLRLSTPV 1120
            T    P     +TT  + PT       T   T I+   T    P+ T T   +   +TP+
Sbjct: 3179 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT---TTPI 3235

Query: 1121 TAKAETTLFSTSVDTVTPSTH-----TLVCSKPPPDNIP-----PASSTHVISTTSTPEA 1170
            T     T   T   T TP+T      T V   P P         P ++T  ++ T TP  
Sbjct: 3236 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3295

Query: 1171 TQPISQVEETSTYALSFPYTFSGGGVVASLATGTTETSVVDETTPSHISANKLT--TSVN 1228
            TQ  +    T+T  ++ P     G    +    TT T+V    TP+       T  T+  
Sbjct: 3296 TQTPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3354

Query: 1229 SHISSSATYRVHTPVSIQLVTSTSVLSSDKDQMTISLGKTPRTMEVT---------EMSP 1279
            +   +       TP +  + T+T+V  +     T +   TP T   T           +P
Sbjct: 3355 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3414

Query: 1280 SKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSPSEIPLGTPSDGNLASSPTSGSTQI 1339
            +     + +  TP+   T T  P TT I++  T +P+  P GT +     ++P + +T +
Sbjct: 3415 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP---TTTPITTTTTV 3471

Query: 1340 TPTLTSSNTVGVHIPEMSTSLGKTALPSQALTITTFLCPEKESTSALPAYTPRTVEMIVN 1399
            TPT T + T       ++T+   T  P+   T T    P   +T+  P  TP   +    
Sbjct: 3472 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3531

Query: 1400 STYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINTTFSHLHSLRTQPEVTSVASFISEST 1459
            +   T        T+   T T + T+      I TT +   +       T   + I+ +T
Sbjct: 3532 TPITT-------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3584

Query: 1460 QTFPESLSLSTAGLYNDGFTVLSDRITTAFSVPNVPTMLPRESSMATSTPIYQMSSLPVN 1519
               P      T        T  +  ITT  +V   PT  P  +   T+TPI   +++   
Sbjct: 3585 TVTPTPTPTGTQ-------TPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPT 3635

Query: 1520 VTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPATVSS 1579
             T   ++  + TP    T  + T  P   ++P T      + ++  P      TP T   
Sbjct: 3636 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3695

Query: 1580 DTSTRVGLFSTLLSSVTPRTTMTMQTSTLDVTPVIYAGATSKNKMVSSAFTTEMIEAPSR 1639
             T+T V    T   + TP TT    T+T+  TP      T     +++  T      P+ 
Sbjct: 3696 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3755

Query: 1640 I-TPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSPL------SSKSTGAISSIP 1692
              TPTT    T  T+    T PT       TP   TT  +P        + +T  I++  
Sbjct: 3756 TQTPTTTPITTTTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3814

Query: 1693 KTTFSPFLSATQQSSQADEATTLGILSGITNRSLSTVNSGTGVALTDTYSRITVPENMLS 1752
              T +P  + TQ  +     TT  +    T     T  + T +  T T +    P    +
Sbjct: 3815 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQT 3873

Query: 1753 PTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLLEKTSLTNYAT 1812
            PT      T+    V+P+ T   + +  T  + TTT    + T   T     T +T   T
Sbjct: 3874 PTTTPITTTT---TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT--T 3928

Query: 1813 SLNTPVSYPPWTPSSATLPSLTSFVYSPHSTEAEISTPKTSPPPTSQMVEFPVLGTRMTS 1872
            +  TP   P  T +  T P  T+   +P  T     TP T+P  T+  V      T   +
Sbjct: 3929 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3988

Query: 1873 SNTQPLLMTSW--NIPTAEGSQFPISTTINVPTSNEMETETLHLVPGPLSTFTASQTGLV 1930
              T P+  T+     PT  G+Q P +T I   T       T+   P P  T T + T + 
Sbjct: 3989 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-------TVTPTPTPTGTQTPTTTPIT 4041

Query: 1931 SKDVMAMSSIPMSGILPNHGLSENPSLSTSLRAITSTLADVKHTFEKMTTSVTP-----G 1985
            +   +  +  P     P        +  T     T T      T    TT+VTP     G
Sbjct: 4042 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTG 4100

Query: 1986 TTLPSILSGATSGSVISKSPILTWLLSSLPSGSPPATVSNAPHVMTSSTVEVSKST-FLT 2044
            T  P+     T+ +V   +P  T   +  P+ +P  T +      T +  +   +T   T
Sbjct: 4101 TQTPTTTPITTTTTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4157

Query: 2045 SDMISAHPFTNLTTLPSATMSTILTRTIPTPTLGGITTGFPT------------------ 2086
            +  ++  P    T  P+ T  T  T   PTPT  G  TG PT                  
Sbjct: 4158 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPE 4217

Query: 2087 ------SLPMSINVTDDIVYISTHPEASSRT-----------TITANPRTVSHPSSFSRK 2129
                  S   S  +T+    +ST P A   T           T T+   T+S P S +  
Sbjct: 4218 SSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTS 4277

Query: 2130 TMSPSTTDHTLSVGAMPLPS---STITSSWNRIPT-ASSPS----TLIIPKPTLDSLLNI 2181
                 T   T    + P PS   +T TS+W   PT  S+PS    T + P P+   +  +
Sbjct: 4278 PPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCV 4337

Query: 2182 MTTTSTVPGASFPLISTGVTYPFTATVSSPISSFFETTWLDSTPSFLSTEASTSPTATK 2240
            +  T   PG      + G T  F     S    F+  +   STPS   T + ++PT +K
Sbjct: 4338 LNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWS-CPSTPSPTPTPSKSTPTPSK 4395



 Score =  341 bits (875), Expect = 6e-93
 Identities = 465/2012 (23%), Positives = 726/2012 (36%), Gaps = 194/2012 (9%)

Query: 261  QNTAHSSTLLSQSIPIFATDYTTISYSNTTSPPLETMTAQKILKTLVDETATFAVDVLST 320
            Q T  ++T      P   T  TT +    T  P  T T      T    T T  V    T
Sbjct: 1881 QPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTP-----TTTPITTTTTVTPTPT 1935

Query: 321  SSAISLPTQSISIDNTTNSMKKTKSPSSESTKTTKMVEAMATEIFQPPTPSNFLSTSRFT 380
             +    PT +     TT ++  T +P+   T TT  +    T +   PTP+   + +   
Sbjct: 1936 PTGTQTPTTTPI--TTTTTVTPTPTPTGTQTPTTTPITTTTT-VTPTPTPTGTQTPTTTP 1992

Query: 381  KNSVVSTTSAIKSQSAVTKTTSLFSTIESTSMSTTPCLKQKSTNTGALPISTAGQEFIES 440
              +  + T         T TT+  +T  + + + TP   Q  T T   PI+T        
Sbjct: 1993 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTP 2049

Query: 441  TAAGTVPWFTVEKTSPASTHVGTASSFPPEPVLISTAAPVDSVFPRNQTAFPLATTDMKI 500
            T  GT         +P +T + T ++  P P    T  P  +      T  P  T     
Sbjct: 2050 TPTGT--------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2101

Query: 501  AFTVHSLTLPTRLIETTPAPRTAETELTSTNFQDVSLPRVEDAMSTSMSKETSSKTFSFL 560
              T   +T  T  +  TP P   +T  T+      ++        T     T   T + +
Sbjct: 2102 TPTTTPITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2160

Query: 561  TSFSF-TGTESVQTVIDAEATRTALTPEITLASTVAETMLSSTITGRVYTQNTPTADGHL 619
            T     TGT++  T      T    TP  T   T   T +++T T       TPT  G  
Sbjct: 2161 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT----VTPTPTPTGTQ 2216

Query: 620  LTLMSTRSASTSKAPESGPTSTTDEAAHLFSSNETIWTSRPDQALLASMNTTTILTFVPN 679
                +  + +T+  P   PT T        ++  T+ T  P      +  TT I T    
Sbjct: 2217 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTV 2275

Query: 680  ENFTSAFHENTTYTEYLSATTNITPLKASPEGKGTTANDATTARYTTAVSKLTSPWFANF 739
                +     T  T  ++ TT +TP   +P   GT     T    TT V+   +P     
Sbjct: 2276 TPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP----- 2327

Query: 740  SIVSGTTSITNMPEFKLTTLLLKTIPMSTKPANELPLTPRETVVPSVDIISTLACIQPNF 799
               +GT + T  P    TT+     P  T+     P+T   TV P+     T        
Sbjct: 2328 ---TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2384

Query: 800  STEESASET-----TQTEINGAIVFGGTTTPVPKSATTQRLNATVTRKEATSHYLMRKST 854
            +T  + + T     TQT     I    T TP P    TQ    T                
Sbjct: 2385 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---------------P 2429

Query: 855  IAAVAEVSPFSTMLEVTDESAQRVTASVTVSSFPDIEKLSTPLDNKTATTEVRESWLLTK 914
            I     V+P  T       +   +T + TV+  P      TP   +T TT        T 
Sbjct: 2430 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTPTT--------TP 2475

Query: 915  LVKTTPRSSYNEMTEMFNFNHTYVAHWTSETSEGISAGSPTSGSTHIFGEPLGASTTRIS 974
            +  TT  +     T       T +   T+ T      G+ T  +T I       +TT ++
Sbjct: 2476 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------TTTTTVT 2529

Query: 975  ETSFST---TPTDRTATSLSDGILPPQPTAAHS-SATPVPVTHMFSLPVNGSSVVAEETE 1030
             T   T   TPT    T+ +     P PT   + + TP+  T         ++V    T 
Sbjct: 2530 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT---------TTVTPTPTP 2580

Query: 1031 VTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVPPLDQTASTTIVIVPTHGDLIRTTSE 1090
                 P+T     +T+V    +   + T TT    P+  T + T    PT      TT  
Sbjct: 2581 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTTTPI 2637

Query: 1091 ATVISVRKTSMAVPSLTETPFHSLRLSTPVTAKAETTLFSTSVDTVTPSTHTLVCSKPPP 1150
             T  +V  T    P+ T+TP      +TP+T     T   T   T TP+T          
Sbjct: 2638 TTTTTVTPTP--TPTGTQTP-----TTTPITTTTTVTPTPTPTGTQTPTT---------- 2680

Query: 1151 DNIPPASSTHVISTTSTPEATQPISQVEETSTYALSFPYTFSGGGVVASLATGTTETSVV 1210
                P ++T  ++ T TP  TQ  +    T+T  ++ P     G    +    TT T+V 
Sbjct: 2681 ---TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTTVT 2736

Query: 1211 DETTPSHISANKLTTSVNSHISSSATYRVHTPVSIQLVTSTSVLSSDKDQMTISLGKTPR 1270
               TP+  +    TT + +  + + T    TP   Q  T+T +        T +   TP 
Sbjct: 2737 PTPTPTG-TQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPI--------TTTTTVTPT 2784

Query: 1271 TMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSPSEIPLGTPSDGNLAS 1330
                   +P+     + +  TP+   T T  P TT I++  T +P+  P GT +     +
Sbjct: 2785 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP---TT 2841

Query: 1331 SPTSGSTQITPTLTSSNTVGVHIPEMSTSLGKTALPSQALTITTFLCPEKESTSALPAYT 1390
            +P + +T +TPT T + T       ++T+   T  P+   T T    P   +T+  P  T
Sbjct: 2842 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2901

Query: 1391 PRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINTTFSHLHSLRTQPEVTS 1450
            P   +    +   T        T+   T T + T+      I TT +   +       T 
Sbjct: 2902 PTGTQTPTTTPITT-------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2954

Query: 1451 VASFISESTQTFPESLSLSTAGLYNDGFTVLSDRITTAFSVPNVPTMLPRESSMATSTPI 1510
              + I+ +T   P      T        T  +  ITT  +V   PT  P  +   T+TPI
Sbjct: 2955 TTTPITTTTTVTPTPTPTGTQ-------TPTTTPITTTTTVTPTPT--PTGTQTPTTTPI 3005

Query: 1511 YQMSSLPVNVTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTATSGPMSEMSSIPVNNS 1570
               +++    T   ++  + TP    T  + T  P   ++P T      + ++  P    
Sbjct: 3006 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3065

Query: 1571 AFTPATVSSDTSTRVGLFSTLLSSVTPRTTMTMQTSTLDVTPVIYAGATSKNKMVSSAFT 1630
              TP T    T+T V    T   + TP TT    T+T+  TP      T     +++  T
Sbjct: 3066 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3125

Query: 1631 TEMIEAPSRI-TPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSPL------SSK 1683
                  P+   TPTT    T  T+    T PT       TP   TT  +P        + 
Sbjct: 3126 VTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3184

Query: 1684 STGAISSIPKTTFSPFLSATQQSSQADEATTLGILSGITNRSLSTVNSGTGVALTDTYSR 1743
            +T  I++    T +P  + TQ  +     TT  +    T     T  + T +  T T + 
Sbjct: 3185 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTP 3243

Query: 1744 ITVPENMLSPTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLLE 1803
               P    +PT      T+    V+P+ T   + +  T  + TTT    + T   T    
Sbjct: 3244 TPTPTGTQTPTTTPITTTT---TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3300

Query: 1804 KTSLTNYATSLNTPVSYPPWTPSSATLPSLTSFVYSPHSTEAEISTPKTSPPPTSQMVEF 1863
             T +T   T+  TP   P  T +  T P  T+   +P  T     TP T+P  T+  V  
Sbjct: 3301 TTPITT--TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3358

Query: 1864 PVLGTRMTSSNTQPLLMTSW--NIPTAEGSQFPISTTINVPTSNEMETETLHLVPGPLST 1921
                T   +  T P+  T+     PT  G+Q P +T I   T       T+   P P  T
Sbjct: 3359 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-------TVTPTPTPTGT 3411

Query: 1922 FTASQTGLVSKDVMAMSSIPMSGILPNHGLSENPSLSTSLRAITSTLADVKHTFEKMTTS 1981
             T + T + +   +  +  P     P          +T+    T+T+          T +
Sbjct: 3412 QTPTTTPITTTTTVTPTPTPTGTQTP----------TTTPITTTTTVTPTPTPTGTQTPT 3461

Query: 1982 VTPGTTLPSILSGAT-SGSVISKSPILTWLLSSLPSGSPPATVSNAPHVMTSSTVEVSKS 2040
             TP TT  ++    T +G+    +  +T   +  P+ +P  T +     +T++T      
Sbjct: 3462 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3521

Query: 2041 TFLTSDMISAHPFTNLTTLP---------SATMSTILTRTIPTPTLGGITTGFPTSLPMS 2091
            T   +   +  P T  TT+          + T + I T T  TPT     T  PT+ P++
Sbjct: 3522 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3581

Query: 2092 INVTDDIVYISTHPEASSRTTITANPRTVSHPSSFSRKTMSPSTTDHTLSVGAMPLPSST 2151
               T       T  +  + T IT    T   P+     T +P+TT  T +    P P+ T
Sbjct: 3582 TTTTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3639

Query: 2152 ITSSWNRIPTASSPSTLIIPKPT---LDSLLNIMTTTSTVPGASFPLISTGVTYPFTATV 2208
             T +    P  ++ +    P PT     +   I TTT+  P  +     T  T P T T 
Sbjct: 3640 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3699

Query: 2209 S-SPISSFFETTWLDSTPSFLSTEASTSPTAT 2239
            + +P  +   T    +TP   +T  + +PT T
Sbjct: 3700 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3731



 Score =  328 bits (840), Expect = 7e-89
 Identities = 489/2126 (23%), Positives = 759/2126 (35%), Gaps = 197/2126 (9%)

Query: 231  PENMTIQEKSTTVSQQIDMTTPSQITGVKPQNTAHSSTLLSQSIPIFATDYTTISYSNTT 290
            P   T    +TT +     TTPS  T       A ++TL   + P   T  TT     TT
Sbjct: 1479 PPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTT 1538

Query: 291  -SPPLETMTAQKILKTLVDETATFAVDVLSTSSAISLPTQSISIDNTTNSMKKTKSPSSE 349
             SPP  T        T +  T T +     T++    PT + S   TT     T + ++ 
Sbjct: 1539 PSPPTTTPITPPTSTTTLPPTTTPSPP--PTTTTTPPPTTTPSPPTTTTPSPPTITTTTP 1596

Query: 350  STKTTKMVEAMATEIFQPPTPSNFLSTSRFTKNSVVST--TSAIKSQSAVTKTTSLFSTI 407
               TT       T    P T  +  +T+  T  +  +T   +   S    T TT   +T 
Sbjct: 1597 PPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTT 1656

Query: 408  ESTSMSTTP------CLKQKSTNTGALPISTAGQEFIESTAAGTVPWFTVEKTSPASTHV 461
             S   +TTP            T T + PI+T        T   T P  T   +SP +T  
Sbjct: 1657 PSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPS---PPTTTMTTPSPTTTPSSPITTTT 1713

Query: 462  GTASSFPPE--PVLISTAAPVDSVFP--RNQTAFPLATTDMKIAFT--VHSLTLPTRLIE 515
              +S+  P   P  ++T +P  +  P     T  P  TT   +  T    S+T PT    
Sbjct: 1714 TPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPF 1773

Query: 516  TTPAPRT-----------------------AETEL---------------TSTNFQDVSL 537
            +T  P T                        +TEL                +T + DV +
Sbjct: 1774 STTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPI 1833

Query: 538  PRVEDAMSTSMS-----KETSSKTFSFL-TSFSFTGTESVQ--TVIDAEATRTALTPEIT 589
             ++   +   +S     K    K    +  +F      +VQ    +    T T  T E  
Sbjct: 1834 GQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENP 1893

Query: 590  LASTVAETMLSSTITGRVYTQNTPTADGHLLTLMSTRSASTSKAPESGPTSTTDEAAHLF 649
               T      ++T+T       TPT  G      +  + +T+  P   PT T        
Sbjct: 1894 TPPTTTPITTTTTVT------PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 1947

Query: 650  SSNETIWTSRPDQALLASMNTTTILTFVPNENFTSAFHENTTYTEYLSATTNITPLKASP 709
            ++  T+ T  P      +  TT I T        +     T  T  ++ TT +TP   +P
Sbjct: 1948 TTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TP 2003

Query: 710  EGKGTTANDATTARYTTAVSKLTSPWFANFSIVSGTTSITNMPEFKLTTLLLKTIPMSTK 769
               GT     T    TT V+   +P        +GT + T  P    TT+     P  T+
Sbjct: 2004 TPTGTQTPTTTPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQ 2055

Query: 770  PANELPLTPRETVVPSVDIISTLACIQPNFSTEESASET-----TQTEINGAIVFGGTTT 824
                 P+T   TV P+     T        +T  + + T     TQT     I    T T
Sbjct: 2056 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2115

Query: 825  PVP-----KSATTQRLNATVT---RKEATSHYLMRKSTIAAVAEVSPFSTMLEVTDESAQ 876
            P P     ++ TT  +  T T       T       + I     V+P  T       +  
Sbjct: 2116 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2175

Query: 877  RVTASVTVSSFPDIEKLSTPLDNKTATTEVRESWLLTKLVKTTPRSSYNEMTEMFNFNHT 936
             +T + TV+  P      TP      TT        T     TP  +    T       T
Sbjct: 2176 PITTTTTVTPTPTPTGTQTPTTTPITTT-------TTVTPTPTPTGTQTPTTTPIT-TTT 2227

Query: 937  YVAHWTSETSEGISAGSPTSGSTHIFGEPLGASTTRISETSFSTTPTDRTATSLSDGILP 996
             V    + T       +P + +T +   P    T   + T  +TT T  T T    G   
Sbjct: 2228 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTPTPTPTGTQT 2286

Query: 997  PQPTAAHSSATPVPVTHMFSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSS 1056
            P  T   ++ T  P           ++ +   T VT +   T  +  +T+ ++  + ++ 
Sbjct: 2287 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2346

Query: 1057 TTMTTALVPPLDQTASTTIVIVPTHGDLIRTTSEATVISVRKTSMAVPSLTETPFHSLRL 1116
            T   T    P     +TT  + PT       T   T I+   T    P+ T T       
Sbjct: 2347 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT---QTPT 2403

Query: 1117 STPVTAKAETTLFSTSVDTVTP-----STHTLVCSKPPP-----DNIPPASSTHVISTTS 1166
            +TP+T     T   T   T TP     +T T V   P P         P ++T  ++ T 
Sbjct: 2404 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2463

Query: 1167 TPEATQPISQVEETSTYALSFPYTFSGGGVVASLATGTTETSVVDETTPSHISANKLT-- 1224
            TP  TQ  +    T+T  ++ P     G    +    TT T+V    TP+       T  
Sbjct: 2464 TPTGTQTPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2522

Query: 1225 TSVNSHISSSATYRVHTPVSIQLVTSTSVLSSDKDQMTISLGKTPRTMEVT--------- 1275
            T+  +   +       TP +  + T+T+V  +     T +   TP T   T         
Sbjct: 2523 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2582

Query: 1276 EMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSPSEIPLGTPSDGNLASSPTSG 1335
              +P+     + +  TP+   T T  P TT I++  T +P+  P GT +     ++P + 
Sbjct: 2583 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP---TTTPITT 2639

Query: 1336 STQITPTLTSSNTVGVHIPEMSTSLGKTALPSQALTITTFLCPEKESTSALPAYTPRTVE 1395
            +T +TPT T + T       ++T+   T  P+   T T    P   +T+  P  TP   +
Sbjct: 2640 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2699

Query: 1396 MIVNSTYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINTTFSHLHSLRTQPEVTSVASFI 1455
                +   T        T+   T T + T+      I TT +   +       T   + I
Sbjct: 2700 TPTTTPITT-------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2752

Query: 1456 SESTQTFPESLSLSTAGLYNDGFTVLSDRITTAFSVPNVPTMLPRESSMATSTPIYQMSS 1515
            + +T   P      T        T  +  ITT  +V   PT  P  +   T+TPI   ++
Sbjct: 2753 TTTTTVTPTPTPTGTQ-------TPTTTPITTTTTV--TPTPTPTGTQTPTTTPITTTTT 2803

Query: 1516 LPVNVTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPA 1575
            +    T   ++  + TP    T  + T  P   ++P T      + ++  P      TP 
Sbjct: 2804 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2863

Query: 1576 TVSSDTSTRVGLFSTLLSSVTPRTTMTMQTSTLDVTPVIYAGATSKNKMVSSAFTTEMIE 1635
            T    T+T V    T   + TP TT    T+T+  TP      T     +++  T     
Sbjct: 2864 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2923

Query: 1636 APSRI-TPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSP------LSSKSTGAI 1688
             P+   TPTT    T  T+    T PT       TP   TT  +P        + +T  I
Sbjct: 2924 TPTGTQTPTTTPITTTTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2982

Query: 1689 SSIPKTTFSPFLSATQQSSQADEATTLGILSGITNRSLSTVNSGTGVALTDTYSRITVPE 1748
            ++    T +P  + TQ  +     TT  +    T     T  + T +  T T +    P 
Sbjct: 2983 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPT 3041

Query: 1749 NMLSPTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLLEKTSLT 1808
               +PT      T+    V+P+ T   + +  T  + TTT    + T   T     T +T
Sbjct: 3042 GTQTPTTTPITTTT---TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3098

Query: 1809 NYATSLNTPVSYPPWTPSSATLPSLTSFVYSPHSTEAEISTPKTSPPPTSQMVEFPVLGT 1868
               T+  TP   P  T +  T P  T+   +P  T     TP T+P  T+  V      T
Sbjct: 3099 --TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3156

Query: 1869 RMTSSNTQPLLMTS--WNIPTAEGSQFPISTTINVPTSNEMETETLHLVPGPLSTFTASQ 1926
               +  T P+  T+     PT  G+Q P +T I         T T+   P P  T T + 
Sbjct: 3157 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-------TTTVTPTPTPTGTQTPTT 3209

Query: 1927 TGLVSKDVMAMSSIPMSGILPNHGLSENPSLSTSLRAITSTLADVK---HTFEKMTTSVT 1983
            T + +   +  +  P     P    +  P  +T+    T T    +    T    TT+VT
Sbjct: 3210 TPITTTTTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3265

Query: 1984 P-----GTTLPSILSGATSGSVISKSPILTWLLSSLPSGSPPATVSNAPHVMTSSTVEVS 2038
            P     GT  P+     T+ +V   +P  T   +  P+ +P  T +      T +  +  
Sbjct: 3266 PTPTPTGTQTPTTTPITTTTTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3322

Query: 2039 KST-FLTSDMISAHPFTNLTTLPSATMSTILTRTIPTPTLGGITTGFPTSLPMSINVTDD 2097
             +T   T+  ++  P    T  P+ T  T  T   PTPT  G  T  PT+ P++   T  
Sbjct: 3323 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVT 3380

Query: 2098 IVYISTHPEASSRTTITANPRTVSHPSSFSRKTMSPSTTDHTLSVGAMPLPSSTITSSWN 2157
                 T  +  + T IT    T   P+     T +P+TT  T +    P P+ T T +  
Sbjct: 3381 PTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3438

Query: 2158 RIPTASSPSTLIIPKPT---LDSLLNIMTTTSTVPGASFPLISTGVTYPFTATVS-SPIS 2213
              P  ++ +    P PT     +   I TTT+  P  +     T  T P T T + +P  
Sbjct: 3439 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3498

Query: 2214 SFFETTWLDSTPSFLSTEASTSPTAT 2239
            +   T    +TP   +T  + +PT T
Sbjct: 3499 TPTGTQTPTTTPITTTTTVTPTPTPT 3524



 Score =  327 bits (838), Expect = 1e-88
 Identities = 490/2096 (23%), Positives = 757/2096 (36%), Gaps = 167/2096 (7%)

Query: 220  PTVDRTLRCFVPENMTIQEKSTTVSQQIDMTTPSQITGVKPQNTAHSSTLLSQSIPIFAT 279
            PT+  T     P   T    +TT +     TTPS  T         ++TL   + P    
Sbjct: 1589 PTITTTTP---PPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPP 1645

Query: 280  DYTTISYSNTTSPPLETMT-AQKILKTLVDETATFAVDVLSTSSAISLPTQSISIDNTTN 338
              TT     TT  P  T T +  I  T      T     ++T+ +    T +     TT 
Sbjct: 1646 TTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTP 1705

Query: 339  S--MKKTKSPSSESTKT---TKMVEAMATEIFQPPTPSNFLSTSRFTKNSVVSTTSAIKS 393
            S  +  T +PSS +T +   T M     T    PPT +  ++T   T  S   TT+ +  
Sbjct: 1706 SSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTT--MTTLPPTTTSSPLTTTPL-P 1762

Query: 394  QSAVTKTTSLFSTIESTSMSTTPCLKQKSTNTGALPISTAGQEFIESTAAGTVPWFTVEK 453
             S    T S F    ST+  TTPC+   +  TG L    +G+         T     V  
Sbjct: 1763 PSITPPTFSPF----STTTPTTPCVPLCNW-TGWL---DSGKPNFHKPGGDTELIGDVCG 1814

Query: 454  TSPASTHVGTASSFPPEPV--LISTAAPVDSV--FPRNQTAFPLATTDMKIAFT------ 503
               A+     A+ +P  P+  L  T     SV    +N+   P     M           
Sbjct: 1815 PGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQ 1874

Query: 504  -VHSLTLPTRLIETT---PAPRTAETELTSTNFQDVSLPRVEDAMSTSMSKETSSKTFSF 559
                +T PT +  TT   P P T     T+T       P      +T+    T++ T   
Sbjct: 1875 CCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT--- 1931

Query: 560  LTSFSFTGTESVQTVIDAEATRTALTPEITLASTVAETMLSSTITGRVYTQNTPTADGHL 619
              + + TGT++  T      T    TP  T   T   T +++T T       TPT  G  
Sbjct: 1932 -PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT----VTPTPTPTGTQ 1986

Query: 620  LTLMSTRSASTSKAPESGPTSTTDEAAHLFSSNETIWTSRPDQALLASMNTTTILTFVPN 679
                +  + +T+  P   PT T        ++  T+ T  P      +  TT I T    
Sbjct: 1987 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTV 2045

Query: 680  ENFTSAFHENTTYTEYLSATTNITPLKASPEGKGTTANDATTARYTTAVSKLTSPWFANF 739
                +     T  T  ++ TT +TP   +P   GT     T    TT V+   +P     
Sbjct: 2046 TPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP----- 2097

Query: 740  SIVSGTTSITNMPEFKLTTLLLKTIPMSTKPANELPLTPRETVVPSVDIISTLACIQPNF 799
               +GT + T  P    TT+     P  T+     P+T   TV P+     T        
Sbjct: 2098 ---TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2154

Query: 800  STEESASET-----TQTEINGAIVFGGTTTPVP-----KSATTQRLNATVT---RKEATS 846
            +T  + + T     TQT     I    T TP P     ++ TT  +  T T       T 
Sbjct: 2155 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2214

Query: 847  HYLMRKSTIAAVAEVSPFSTMLEVTDESAQRVTASVTVSSFPDIEKLSTPLDNKTATTEV 906
                  + I     V+P  T       +   +T + TV+  P      TP      TT  
Sbjct: 2215 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-- 2272

Query: 907  RESWLLTKLVKTTPRSSYNEMTEMFNFNHTYVAHWTSETSEGISAGSPTSGSTHIFGEPL 966
                  T     TP  +    T       T V    + T       +P + +T +   P 
Sbjct: 2273 -----TTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2326

Query: 967  GASTTRISETSFSTTPTDRTATSLSDGILPPQPTAAHSSATPVPVTHMFSLPVNGSSVVA 1026
               T   + T  +TT T  T T    G   P  T   ++ T  P           ++ + 
Sbjct: 2327 PTGTQTPTTTPITTT-TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2385

Query: 1027 EETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVPPLDQTASTTIVIVPTHGDLIR 1086
              T VT +   T  +  +T+ ++  + ++ T   T    P     +TT  + PT      
Sbjct: 2386 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2445

Query: 1087 TTSEATVISVRKTSMAVPSLTETPFHSLRLSTPVTAKAETTLFSTSVDTVTP-----STH 1141
             T   T I+   T    P+ T T       +TP+T     T   T   T TP     +T 
Sbjct: 2446 QTPTTTPITTTTTVTPTPTPTGT---QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2502

Query: 1142 TLVCSKPPP-----DNIPPASSTHVISTTSTPEATQPISQVEETSTYALSFPYTFSGGGV 1196
            T V   P P         P ++T  ++ T TP  TQ  +    T+T  ++ P     G  
Sbjct: 2503 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-PTPTPTGTQ 2561

Query: 1197 VASLATGTTETSVVDETTPSHISANKLT--TSVNSHISSSATYRVHTPVSIQLVTSTSVL 1254
              +    TT T+V    TP+       T  T+  +   +       TP +  + T+T+V 
Sbjct: 2562 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2621

Query: 1255 SSDKDQMTISLGKTPRTMEVT---------EMSPSKNSFISYSRGTPSLEMTDTGFPETT 1305
             +     T +   TP T   T           +P+     + +  TP+   T T  P TT
Sbjct: 2622 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2681

Query: 1306 KISSHQTHSPSEIPLGTPSDGNLASSPTSGSTQITPTLTSSNTVGVHIPEMSTSLGKTAL 1365
             I++  T +P+  P GT +     ++P + +T +TPT T + T       ++T+   T  
Sbjct: 2682 PITTTTTVTPTPTPTGTQTP---TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2738

Query: 1366 PSQALTITTFLCPEKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSSTR 1425
            P+   T T    P   +T+  P  TP   +    +   T        T+   T T + T+
Sbjct: 2739 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-------TTTVTPTPTPTGTQ 2791

Query: 1426 ISNPMDINTTFSHLHSLRTQPEVTSVASFISESTQTFPESLSLSTAGLYNDGFTVLSDRI 1485
                  I TT +   +       T   + I+ +T   P      T        T  +  I
Sbjct: 2792 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-------TPTTTPI 2844

Query: 1486 TTAFSVPNVPTMLPRESSMATSTPIYQMSSLPVNVTAFTSKKVSDTPPIVITKSSKTMHP 1545
            TT  +V   PT  P  +   T+TPI   +++    T   ++  + TP    T  + T  P
Sbjct: 2845 TTTTTV--TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2902

Query: 1546 GCLKSPCTATSGPMSEMSSIPVNNSAFTPATVSSDTSTRVGLFSTLLSSVTPRTTMTMQT 1605
               ++P T      + ++  P      TP T    T+T V    T   + TP TT    T
Sbjct: 2903 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2962

Query: 1606 STLDVTPVIYAGATSKNKMVSSAFTTEMIEAPSRI-TPTTFLSPTEPTLPFVKTVPTTIM 1664
            +T+  TP      T     +++  T      P+   TPTT    T  T+    T PT   
Sbjct: 2963 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ 3021

Query: 1665 AGIVTPFVGTTAFSP------LSSKSTGAISSIPKTTFSPFLSATQQSSQADEATTLGIL 1718
                TP   TT  +P        + +T  I++    T +P  + TQ  +     TT  + 
Sbjct: 3022 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3081

Query: 1719 SGITNRSLSTVNSGTGVALTDTYSRITVPENMLSPTHADSLHTSFNIQVSPSLTSFKSAS 1778
               T     T  + T +  T T +    P    +PT      T+    V+P+ T   + +
Sbjct: 3082 PTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTT---TVTPTPTPTGTQT 3137

Query: 1779 GPTKNVKTTTNCFSSNTRKMTSLLEKTSLTNYATSLNTPVSYPPWTPSSATLPSLTSFVY 1838
              T  + TTT    + T   T     T +T   T+  TP   P  T +  T P  T+   
Sbjct: 3138 PTTTPITTTTTVTPTPTPTGTQTPTTTPIT--TTTTVTPTPTPTGTQTPTTTPITTTTTV 3195

Query: 1839 SPHSTEAEISTPKTSPPPTSQMVEFPVLGTRMTSSNTQPLLMTS--WNIPTAEGSQFPIS 1896
            +P  T     TP T+P  T+  V      T   +  T P+  T+     PT  G+Q P +
Sbjct: 3196 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3255

Query: 1897 TTINVPTSNEMETETLHLVPGPLSTFTASQTGLVSKDVMAMSSIPMSGILPNHGLSENPS 1956
            T I         T T+   P P  T T + T + +   +  +  P     P    +  P 
Sbjct: 3256 TPITT-------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPI 3304

Query: 1957 LSTSLRAITSTLADVK---HTFEKMTTSVTP-----GTTLPSILSGATSGSVISKSPILT 2008
             +T+    T T    +    T    TT+VTP     GT  P+     T+ +V   +P  T
Sbjct: 3305 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV---TPTPT 3361

Query: 2009 WLLSSLPSGSPPATVSNAPHVMTSSTVEVSKST-FLTSDMISAHPFTNLTTLPSATMSTI 2067
               +  P+ +P  T +      T +  +   +T   T+  ++  P    T  P+ T  T 
Sbjct: 3362 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3421

Query: 2068 LTRTIPTPTLGGITTGFPTSLPMSINVTDDIVYISTHPEASSRTTITANPRTVSHPSSFS 2127
             T   PTPT  G  T  PT+ P++   T       T  +  + T IT    T   P+   
Sbjct: 3422 TTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTP 3477

Query: 2128 RKTMSPSTTDHTLSVGAMPLPSSTITSSWNRIPTASSPSTLIIPKPT---LDSLLNIMTT 2184
              T +P+TT  T +    P P+ T T +    P  ++ +    P PT     +   I TT
Sbjct: 3478 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3537

Query: 2185 TSTVPGASFPLISTGVTYPFTATVS-SPISSFFETTWLDSTPSFLSTEASTSPTAT 2239
            T+  P  +     T  T P T T + +P  +   T    +TP   +T  + +PT T
Sbjct: 3538 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3593



 Score =  309 bits (791), Expect = 3e-83
 Identities = 479/2115 (22%), Positives = 742/2115 (35%), Gaps = 202/2115 (9%)

Query: 249  MTTPSQITGVKPQNTAHSSTLLSQSIPIFATDYTTISYSNTTSPPLETMTAQKILKTLVD 308
            +TTPS  T         ++TL   + P   T       + TT+PP  T  +  I  T   
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPT-------TTTTTPPPTTTPSPPITTTTTP 1448

Query: 309  ETATFAVDVLSTSSAISLPTQSISIDNTTNSMKKTKSPSSESTKTTKMVEAMATEIFQPP 368
               T     +ST++    PT + S   TT S   T +PS  +T TT       T    PP
Sbjct: 1449 PPTTTPSPPISTTTT-PPPTTTPSPPTTTPS-PPTTTPSPPTTTTT---TPPPTTTPSPP 1503

Query: 369  TPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFSTIESTSMSTTPCLKQKSTNTGAL 428
            T +     +  T     +T S        T TT+   T   +  +TTP     ST T  L
Sbjct: 1504 TTTPITPPASTTTLPPTTTPS-----PPTTTTTTPPPTTTPSPPTTTPITPPTSTTT--L 1556

Query: 429  PISTAGQEFIESTAAGTVPWFTVEK----TSPASTHVGTASSFP---PEPVLISTAAPVD 481
            P +T        T   T P  T       T+P+   + T +  P   P P   +T  P  
Sbjct: 1557 PPTTTPSP--PPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPP 1614

Query: 482  SVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETTPAPRTAETELTSTN----FQDVSL 537
            +  P   T  P+            +   P     TTP P T  +  T+T         + 
Sbjct: 1615 TTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTT 1674

Query: 538  PRVEDAMSTSMSKETSSKTFSFLTSFSFTGTESVQTVIDAEATRTALTPEITLASTVAET 597
            P      S+ ++   S  T +  T    T   S  T     ++ T  +P  T  +T + T
Sbjct: 1675 PPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPT 1734

Query: 598  MLSSTITGRVYTQNTPTADGHLLTL-------------MSTRSASTSKAPESGPTSTTDE 644
               S  T  + T    T    L T               ST + +T   P    T   D 
Sbjct: 1735 TTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDS 1794

Query: 645  AAHLF----------------------SSNETIWTSRP----DQALLASMNTTTI----- 673
                F                      S   T++   P     Q ++  ++   I     
Sbjct: 1795 GKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNED 1854

Query: 674  --------LTFVPNENFTSAFHENTTYTEYLSATTNITPLKASPEGKGTTANDATTARYT 725
                    + F  N        E  T    ++ TT   P   +     TT     T   T
Sbjct: 1855 QKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPT 1914

Query: 726  TAVSKLTSPWFANFSIV-----SGTTSITNMPEFKLTTLLLKTIPMSTKPANELPLTPRE 780
               +  T+P     ++      +GT + T  P    TT+     P  T+     P+T   
Sbjct: 1915 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 1974

Query: 781  TVVPSVDIISTLACIQPNFSTEESASET-----TQTEINGAIVFGGTTTPVP-----KSA 830
            TV P+     T        +T  + + T     TQT     I    T TP P     ++ 
Sbjct: 1975 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2034

Query: 831  TTQRLNATVT---RKEATSHYLMRKSTIAAVAEVSPFSTMLEVTDESAQRVTASVTVSSF 887
            TT  +  T T       T       + I     V+P  T       +   +T + TV+  
Sbjct: 2035 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2094

Query: 888  PDIEKLSTPLDNKTATTEVRESWLLTKLVKTTPRSSYNEMTEMFNFNHTYVAHWTSETSE 947
            P      TP      TT        T     TP  +    T       T V    + T  
Sbjct: 2095 PTPTGTQTPTTTPITTT-------TTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGT 2146

Query: 948  GISAGSPTSGSTHIFGEPLGASTTRISETSFSTTPTDRTATSLSDGILPPQPTAAHSSAT 1007
                 +P + +T +   P    T   + T  +TT T  T T    G   P  T   ++ T
Sbjct: 2147 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTPTPTPTGTQTPTTTPITTTTT 2205

Query: 1008 PVPVTHMFSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVPPL 1067
              P           ++ +   T VT +   T  +  +T+ ++  + ++ T   T    P 
Sbjct: 2206 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2265

Query: 1068 DQTASTTIVIVPTHGDLIRTTSEATVISVRKTSMAVPSLTETPFHSLRLSTPVTAKAETT 1127
                +TT  + PT       T   T I+   T    P+ T T       +TP+T     T
Sbjct: 2266 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT---QTPTTTPITTTTTVT 2322

Query: 1128 LFSTSVDTVTP-----STHTLVCSKPPP-----DNIPPASSTHVISTTSTPEATQPISQV 1177
               T   T TP     +T T V   P P         P ++T  ++ T TP  TQ  +  
Sbjct: 2323 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2382

Query: 1178 EETSTYALSFPYTFSGGGVVASLATGTTETSVVDETTPSHISANKLT--TSVNSHISSSA 1235
              T+T  ++ P     G    +    TT T+V    TP+       T  T+  +   +  
Sbjct: 2383 PITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2441

Query: 1236 TYRVHTPVSIQLVTSTSVLSSDKDQMTISLGKTPRTMEVT---------EMSPSKNSFIS 1286
                 TP +  + T+T+V  +     T +   TP T   T           +P+     +
Sbjct: 2442 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2501

Query: 1287 YSRGTPSLEMTDTGFPETTKISSHQTHSPSEIPLGTPSDGNLASSPTSGSTQITPTLTSS 1346
             +  TP+   T T  P TT I++  T +P+  P GT +     ++P + +T +TPT T +
Sbjct: 2502 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP---TTTPITTTTTVTPTPTPT 2558

Query: 1347 NTVGVHIPEMSTSLGKTALPSQALTITTFLCPEKESTSALPAYTPRTVEMIVNSTYVTHS 1406
             T       ++T+   T  P+   T T    P   +T+  P  TP   +    +   T  
Sbjct: 2559 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-- 2616

Query: 1407 VSYGQDTSFVDTTTSSSTRISNPMDINTTFSHLHSLRTQPEVTSVASFISESTQTFPESL 1466
                  T+   T T + T+      I TT +   +       T   + I+ +T   P   
Sbjct: 2617 -----TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2671

Query: 1467 SLSTAGLYNDGFTVLSDRITTAFSVPNVPTMLPRESSMATSTPIYQMSSLPVNVTAFTSK 1526
               T        T  +  ITT  +V   PT  P  +   T+TPI   +++    T   ++
Sbjct: 2672 PTGTQ-------TPTTTPITTTTTV--TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2722

Query: 1527 KVSDTPPIVITKSSKTMHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPATVSSDTSTRVG 1586
              + TP    T  + T  P   ++P T      + ++  P      TP T    T+T V 
Sbjct: 2723 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2782

Query: 1587 LFSTLLSSVTPRTTMTMQTSTLDVTPVIYAGATSKNKMVSSAFTTEMIEAPSRI-TPTTF 1645
               T   + TP TT    T+T+  TP      T     +++  T      P+   TPTT 
Sbjct: 2783 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2842

Query: 1646 LSPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSP------LSSKSTGAISSIPKTTFSPF 1699
               T  T+    T PT       TP   TT  +P        + +T  I++    T +P 
Sbjct: 2843 PITTTTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2901

Query: 1700 LSATQQSSQADEATTLGILSGITNRSLSTVNSGTGVALTDTYSRITVPENMLSPTHADSL 1759
             + TQ  +     TT  +    T     T  + T +  T T +    P    +PT     
Sbjct: 2902 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPIT 2960

Query: 1760 HTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLLEKTSLTNYATSLNTPVS 1819
             T+    V+P+ T   + +  T  + TTT    + T   T     T +T   T+  TP  
Sbjct: 2961 TTT---TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT--TTTTVTPTP 3015

Query: 1820 YPPWTPSSATLPSLTSFVYSPHSTEAEISTPKTSPPPTSQMVEFPVLGTRMTSSNTQPLL 1879
             P  T +  T P  T+   +P  T     TP T+P  T+  V      T   +  T P+ 
Sbjct: 3016 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3075

Query: 1880 MTS--WNIPTAEGSQFPISTTINVPTSNEMETETLHLVPGPLSTFTASQTGLVSKDVMAM 1937
             T+     PT  G+Q P +T I         T T+   P P  T T + T + +   +  
Sbjct: 3076 TTTTVTPTPTPTGTQTPTTTPITT-------TTTVTPTPTPTGTQTPTTTPITTTTTVTP 3128

Query: 1938 SSIPMSGILPNHGLSENPSLSTSLRAITSTLADVK---HTFEKMTTSVTP-----GTTLP 1989
            +  P     P    +  P  +T+    T T    +    T    TT+VTP     GT  P
Sbjct: 3129 TPTPTGTQTP----TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3184

Query: 1990 SILSGATSGSVISKSPILTWLLSSLPSGSPPATVSNAPHVMTSSTVEVSKST-FLTSDMI 2048
            +     T+ +V   +P  T   +  P+ +P  T +      T +  +   +T   T+  +
Sbjct: 3185 TTTPITTTTTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3241

Query: 2049 SAHPFTNLTTLPSATMSTILTRTIPTPTLGGITTGFPTSLPMSINVTDDIVYISTHPEAS 2108
            +  P    T  P+ T  T  T   PTPT  G  T  PT+ P++   T       T  +  
Sbjct: 3242 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTP 3299

Query: 2109 SRTTITANPRTVSHPSSFSRKTMSPSTTDHTLSVGAMPLPSSTITSSWNRIPTASSPSTL 2168
            + T IT    T   P+     T +P+TT  T +    P P+ T T +    P  ++ +  
Sbjct: 3300 TTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3357

Query: 2169 IIPKPT---LDSLLNIMTTTSTVPGASFPLISTGVTYPFTATVS-SPISSFFETTWLDST 2224
              P PT     +   I TTT+  P  +     T  T P T T + +P  +   T    +T
Sbjct: 3358 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3417

Query: 2225 PSFLSTEASTSPTAT 2239
            P   +T  + +PT T
Sbjct: 3418 PITTTTTVTPTPTPT 3432



 Score =  308 bits (789), Expect = 5e-83
 Identities = 476/2066 (23%), Positives = 745/2066 (36%), Gaps = 255/2066 (12%)

Query: 235  TIQEKSTTVSQQIDMTT-PSQITGVKPQNTAHSSTLLSQSIPIFATDYTTISYSNTTSPP 293
            T    +TT S  I  TT P   T   P  T  S    + S P   T  TT   + T SPP
Sbjct: 1446 TTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTT--TTPPPTTTPSPP 1503

Query: 294  LETMTAQKILKTLVDETATFAVDVLSTSSAISLPTQS------ISIDNTTNSMKKTKSPS 347
              T        T +  T T +    +T++     T S      I+   +T ++  T +PS
Sbjct: 1504 TTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPS 1563

Query: 348  SESTKTTKMVEAMATEIFQPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFSTI 407
               T TT            PPT +    T+       ++TT+   + +    TT+  +  
Sbjct: 1564 PPPTTTTT----------PPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPP 1613

Query: 408  ESTSMS---TTPCLKQKSTNTGALPISTAGQEFIESTAAGTVPWFTVEKTSPASTHVGTA 464
             +T+ S   TTP     ST T  LP +T              P  T   T P +T     
Sbjct: 1614 PTTTPSPPTTTPITPPTSTTT--LPPTTTPS-----------PPPTTTTTPPPTTTPSPP 1660

Query: 465  SSFPPEPVLISTAAPVDSVFPRNQTAFPLATTDMKIAFTVHS---LTLPTRLIETTPAPR 521
            ++  P P + +T  P  +  P +    P+ TT      T+ +    T P+  I TT  P 
Sbjct: 1661 TTTTPSPPITTTTTPPPTTTPSS----PITTTPSPPTTTMTTPSPTTTPSSPITTTTTPS 1716

Query: 522  TAETELTSTNFQDVSLPRVEDAM-STSMSKETSSKTFSFLTSFSFTGTESVQTVIDAEAT 580
            +  T            P    +  +T+M+    + T S LT+     + +  T     +T
Sbjct: 1717 STTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPT-FSPFST 1775

Query: 581  RTALTPEITLASTVA--------------ETMLSSTITGRVYTQNTPTADGHLLTLMSTR 626
             T  TP + L +                 +T L   + G  +  N           +S R
Sbjct: 1776 TTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAAN-----------ISCR 1824

Query: 627  SASTSKAP--ESGPTSTTDEAAHLFSSNETIWTSRPDQALLAS------MNTTTILTFVP 678
            +      P  + G T   D +  L   NE     +P   +  +      +N         
Sbjct: 1825 ATMYPDVPIGQLGQTVVCDVSVGLICKNED---QKPGGVIPMAFCLNYEINVQCCECVTQ 1881

Query: 679  NENFTSAFHENTT--YTEYLSATTNITPLKASPEGKGTTANDATTARYTTAVSKLTSPWF 736
                T+   EN T   T  ++ TT +TP   +P   GT     T    TT V+   +P  
Sbjct: 1882 PTTMTTTTTENPTPPTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTP-- 1936

Query: 737  ANFSIVSGTTSITNMPEFKLTTLLLKTIPMSTKPANELPLTPRETVVPSVDIISTLACIQ 796
                  +GT + T  P    TT+     P  T+     P+T   TV P+     T     
Sbjct: 1937 ------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 1990

Query: 797  PNFSTEESASET-----TQTEINGAIVFGGTTTPVPKSATTQRLNATVTRKEATSHYLMR 851
               +T  + + T     TQT     I    T TP P    TQ    T             
Sbjct: 1991 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT------------- 2037

Query: 852  KSTIAAVAEVSPFSTMLEVTDESAQRVTASVTVSSFPDIEKLSTPLDNKTATTEVRESWL 911
               I     V+P  T       +   +T + TV+  P      TP   +T TT       
Sbjct: 2038 --PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTPTT------- 2082

Query: 912  LTKLVKTTPRSSYNEMTEMFNFNHTYVAHWTSETSEGISAGSPTSGSTHIFGEPLGASTT 971
             T +  TT  +     T       T +   T+ T      G+ T  +T I       +TT
Sbjct: 2083 -TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------TTTT 2135

Query: 972  RISETSFST---TPTDRTATSLSDGILPPQPTAAHS-SATPVPVTHMFSLPVNGSSVVAE 1027
             ++ T   T   TPT    T+ +     P PT   + + TP+  T         ++V   
Sbjct: 2136 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT---------TTVTPT 2186

Query: 1028 ETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVPPLDQTASTTIVIVPTHGDLIRT 1087
             T      P+T     +T+V    +   + T TT    P+  T + T    PT      T
Sbjct: 2187 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTT 2243

Query: 1088 TSEATVISVRKTSMAVPSLTETPFHSLRLSTPVTAKAETTLFSTSVDTVTPSTHTLVCSK 1147
            T   T  +V  T    P+ T+TP      +TP+T     T   T   T TP+T       
Sbjct: 2244 TPITTTTTVTPTP--TPTGTQTP-----TTTPITTTTTVTPTPTPTGTQTPTT------- 2289

Query: 1148 PPPDNIPPASSTHVISTTSTPEATQPISQVEETSTYALSFPYTFSGGGVVASLATGTTET 1207
                   P ++T  ++ T TP  TQ  +    T+T  ++ P     G    +    TT T
Sbjct: 2290 ------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTT 2342

Query: 1208 SVVDETTPSHISANKLTTSVNSHISSSATYRVHTPVSIQLVTSTSVLSSDKDQMTISLGK 1267
            +V    TP+  +    TT + +  + + T    TP   Q  T+T +        T +   
Sbjct: 2343 TVTPTPTPTG-TQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPI--------TTTTTV 2390

Query: 1268 TPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSPSEIPLGTPSDGN 1327
            TP        +P+     + +  TP+   T T  P TT I++  T +P+  P GT +   
Sbjct: 2391 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-- 2448

Query: 1328 LASSPTSGSTQITPTLTSSNTVGVHIPEMSTSLGKTALPSQALTITTFLCPEKESTSALP 1387
              ++P + +T +TPT T + T       ++T+   T  P+   T T    P   +T+  P
Sbjct: 2449 -TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2507

Query: 1388 AYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINTTFSHLHSLRTQPE 1447
              TP   +    +   T        T+   T T + T+      I TT +   +      
Sbjct: 2508 TPTPTGTQTPTTTPITT-------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2560

Query: 1448 VTSVASFISESTQTFPESLSLSTAGLYNDGFTVLSDRITTAFSVPNVPTMLPRESSMATS 1507
             T   + I+ +T   P      T        T  +  ITT  +V   PT  P  +   T+
Sbjct: 2561 QTPTTTPITTTTTVTPTPTPTGTQ-------TPTTTPITTTTTVTPTPT--PTGTQTPTT 2611

Query: 1508 TPIYQMSSLPVNVTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTATSGPMSEMSSIPV 1567
            TPI   +++    T   ++  + TP    T  + T  P   ++P T      + ++  P 
Sbjct: 2612 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2671

Query: 1568 NNSAFTPATVSSDTSTRVGLFSTLLSSVTPRTTMTMQTSTLDVTPVIYAGATSKNKMVSS 1627
                 TP T    T+T V    T   + TP TT    T+T+  TP      T     +++
Sbjct: 2672 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2731

Query: 1628 AFTTEMIEAPSRI-TPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSPL------ 1680
              T      P+   TPTT    T  T+    T PT       TP   TT  +P       
Sbjct: 2732 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGT 2790

Query: 1681 SSKSTGAISSIPKTTFSPFLSATQQSSQADEATTLGILSGITNRSLSTVNSGTGVALTDT 1740
             + +T  I++    T +P  + TQ  +     TT  +    T     T  + T +  T T
Sbjct: 2791 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTT 2849

Query: 1741 YSRITVPENMLSPTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTS 1800
             +    P    +PT      T+    V+P+ T   + +  T  + TTT    + T   T 
Sbjct: 2850 VTPTPTPTGTQTPTTTPITTTT---TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2906

Query: 1801 LLEKTSLTNYATSLNTPVSYPPWTPSSATLPSLTSFVYSPHSTEAEISTPKTSPPPTSQM 1860
                T +T   T+  TP   P  T +  T P  T+   +P  T     TP T+P  T+  
Sbjct: 2907 TPTTTPITT--TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2964

Query: 1861 VEFPVLGTRMTSSNTQPLLMTSW--NIPTAEGSQFPISTTINVPTSNEMETETLHLVPGP 1918
            V      T   +  T P+  T+     PT  G+Q P +T I   T       T+   P P
Sbjct: 2965 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-------TVTPTPTP 3017

Query: 1919 LSTFTASQTGLVSKDVMAMSSIPMSGILPNHGLSENPSLSTSLRAITSTLADVKHTFEKM 1978
              T T + T + +   +  +  P     P          +T+    T+T+          
Sbjct: 3018 TGTQTPTTTPITTTTTVTPTPTPTGTQTP----------TTTPITTTTTVTPTPTPTGTQ 3067

Query: 1979 TTSVTPGTTLPSILSGAT-SGSVISKSPILTWLLSSLPSGSPPATVSNAPHVMTSSTVEV 2037
            T + TP TT  ++    T +G+    +  +T   +  P+ +P  T        T +T  +
Sbjct: 3068 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-------QTPTTTPI 3120

Query: 2038 SKSTFLTSDMISAHPFTNLTTLPSATMSTILTRTIPTPTLGGITTGFPTSLPMSINVTDD 2097
            + +T +T       P    T   + T + I T T  TPT     T  PT+ P++   T  
Sbjct: 3121 TTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3173

Query: 2098 IVYISTHPEASSRTTITANPRTVSHPSSFSRKTMSPSTTDHTLSVGAMPLPSSTITSSWN 2157
                 T  +  + T IT    T   P+     T +P+TT  T +    P P+ T T +  
Sbjct: 3174 PTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3231

Query: 2158 RIPTASSPSTLIIPKPT---LDSLLNIMTTTSTVPGASFPLISTGVTYPFTATVS-SPIS 2213
              P  ++ +    P PT     +   I TTT+  P  +     T  T P T T + +P  
Sbjct: 3232 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3291

Query: 2214 SFFETTWLDSTPSFLSTEASTSPTAT 2239
            +   T    +TP   +T  + +PT T
Sbjct: 3292 TPTGTQTPTTTPITTTTTVTPTPTPT 3317



 Score =  218 bits (554), Expect = 1e-55
 Identities = 327/1344 (24%), Positives = 488/1344 (36%), Gaps = 130/1344 (9%)

Query: 965  PLGASTTRISETSFSTTPTDRTATSLSDGILPPQPTAAHSSATPVPVTHMFSLPVNGSSV 1024
            P+    T  S  + + +P   + T+L     P  PT   ++ TP P T   S P+  ++ 
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTT--TTTTPPPTTTP-SPPITTTTT 1447

Query: 1025 VAEET------EVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVPPLDQTAS--TTIV 1076
                T        T + P T   +  T+  S  +   S   TT   PP   T S  TT  
Sbjct: 1448 PPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTP 1507

Query: 1077 IVPTHGDLIRTTSEATVISVRKTSMAVPSLTETPFHSLRLSTPVTAKAETTLFSTSVDTV 1136
            I P       T    T  S   T+   P  T TP  S   +TP+T    TT   T   T 
Sbjct: 1508 ITPPASTT--TLPPTTTPSPPTTTTTTPPPTTTP--SPPTTTPITPPTSTT---TLPPTT 1560

Query: 1137 TPSTHTLVCSKPPPDNIPPASST------HVISTTSTPEATQPISQVEETSTYALSFPYT 1190
            TPS      + PPP    P+  T        I+TT+ P  T P      T+T     P T
Sbjct: 1561 TPSPPPTTTTTPPPTTT-PSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPP---PTT 1616

Query: 1191 FSGGGVVASLATGTTETSVVDETTPSHISANKLTTSVNSHISSSATYRVHTPVSIQLVTS 1250
                     +   T+ T++   TTPS       T    +  S   T    T  S  + T+
Sbjct: 1617 TPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTT----TTPSPPITTT 1672

Query: 1251 TSVLSSDKDQMTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSH 1310
            T+   +      I+   +P T  +T  SP+          TPS  +T T  P     SS 
Sbjct: 1673 TTPPPTTTPSSPITTTPSPPTTTMTTPSPTT---------TPSSPITTTTTP-----SST 1718

Query: 1311 QTHSPSEIPLGTPSDGNLASSPTSGSTQITPTLTSSNTVGVHIPEMSTSLGKTALPSQAL 1370
             T SP    + TPS     S PT+  T + PT TSS      +P   T    T  P    
Sbjct: 1719 TTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITP--PTFSPFSTT 1776

Query: 1371 TITTFLCPEKESTSALPAYTPR------TVEMIVN------------STYVTHSVSYGQD 1412
            T TT   P    T  L +  P         E+I +               +   V  GQ 
Sbjct: 1777 TPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQL 1836

Query: 1413 TSFVDTTTSSSTRISN---------PM------DINTTFSHLHSLRTQPEVTSVASFISE 1457
               V    S      N         PM      +IN       +  T    T+  +    
Sbjct: 1837 GQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPP 1896

Query: 1458 STQTFPESLSLSTAGLYNDGFTVLSDRITTAFSVPNVPTMLPRESSMATSTPIYQMSSLP 1517
            +T     + +++         T  +  ITT  +V   PT  P  +   T+TPI   +++ 
Sbjct: 1897 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV--TPTPTPTGTQTPTTTPITTTTTVT 1954

Query: 1518 VNVTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPATV 1577
               T   ++  + TP    T  + T  P   ++P T      + ++  P      TP T 
Sbjct: 1955 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2014

Query: 1578 SSDTSTRVGLFSTLLSSVTPRTTMTMQTSTLDVTPVIYAGATSKNKMVSSAFTTEMIEAP 1637
               T+T V    T   + TP TT    T+T+  TP      T     +++  T      P
Sbjct: 2015 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2074

Query: 1638 SRI-TPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSP------LSSKSTGAISS 1690
            +   TPTT    T  T+    T PT       TP   TT  +P        + +T  I++
Sbjct: 2075 TGTQTPTTTPITTTTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2133

Query: 1691 IPKTTFSPFLSATQQSSQADEATTLGILSGITNRSLSTVNSGTGVALTDTYSRITVPENM 1750
                T +P  + TQ  +     TT  +    T     T  + T +  T T +    P   
Sbjct: 2134 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGT 2192

Query: 1751 LSPTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLLEKTSLTNY 1810
             +PT      T+    V+P+ T   + +  T  + TTT    + T   T     T +T  
Sbjct: 2193 QTPTTTPITTTT---TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-- 2247

Query: 1811 ATSLNTPVSYPPWTPSSATLPSLTSFVYSPHSTEAEISTPKTSPPPTSQMVEFPVLGTRM 1870
             T+  TP   P  T +  T P  T+   +P  T     TP T+P  T+  V      T  
Sbjct: 2248 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2307

Query: 1871 TSSNTQPLLMTS--WNIPTAEGSQFPISTTINVPTSNEMETETLHLVPGPLSTFTASQTG 1928
             +  T P+  T+     PT  G+Q P +T I         T T+   P P  T T + T 
Sbjct: 2308 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-------TTTVTPTPTPTGTQTPTTTP 2360

Query: 1929 LVSKDVMAMSSIPMSGILPNHGLSENPSLSTSLRAITSTLADVK---HTFEKMTTSVTP- 1984
            + +   +  +  P     P    +  P  +T+    T T    +    T    TT+VTP 
Sbjct: 2361 ITTTTTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2416

Query: 1985 ----GTTLPSILSGATSGSVISKSPILTWLLSSLPSGSPPATVSNAPHVMTSSTVEVSKS 2040
                GT  P+     T+ +V   +P  T   +  P+ +P  T +      T +  +   +
Sbjct: 2417 PTPTGTQTPTTTPITTTTTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2473

Query: 2041 T-FLTSDMISAHPFTNLTTLPSATMSTILTRTIPTPTLGGITTGFPTSLPMSINVTDDIV 2099
            T   T+  ++  P    T  P+ T  T  T   PTPT  G  T  PT+ P++   T    
Sbjct: 2474 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPT 2531

Query: 2100 YISTHPEASSRTTITANPRTVSHPSSFSRKTMSPSTTDHTLSVGAMPLPSSTITSSWNRI 2159
               T  +  + T IT    T   P+     T +P+TT  T +    P P+ T T +    
Sbjct: 2532 PTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2589

Query: 2160 PTASSPSTLIIPKPT---LDSLLNIMTTTSTVPGASFPLISTGVTYPFTATVS-SPISSF 2215
            P  ++ +    P PT     +   I TTT+  P  +     T  T P T T + +P  + 
Sbjct: 2590 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2649

Query: 2216 FETTWLDSTPSFLSTEASTSPTAT 2239
              T    +TP   +T  + +PT T
Sbjct: 2650 TGTQTPTTTPITTTTTVTPTPTPT 2673



 Score =  142 bits (359), Expect = 4e-33
 Identities = 219/956 (22%), Positives = 319/956 (33%), Gaps = 96/956 (10%)

Query: 235  TIQEKSTTVSQQIDMTTPSQITGVKPQNTAHSSTLLSQSIPIFATDYTTISYSNTTSPPL 294
            T+    T    Q   TTP   T         + T    + PI  T         TT  P 
Sbjct: 3516 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT---------TTVTPT 3566

Query: 295  ETMTAQKILKTLVDETATFAVDVLSTSSAISLPTQSISIDNTTNSMKKTKSPSSESTKTT 354
             T T  +   T    T T    V  T +     T + +   TT ++  T +P+   T TT
Sbjct: 3567 PTPTGTQTPTTTPITTTT---TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3623

Query: 355  KMVEAMATEIFQPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFSTIESTSMST 414
              +    T +   PTP+   + +     +  + T         T TT+  +T  + + + 
Sbjct: 3624 TPITTTTT-VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3682

Query: 415  TPCLKQKSTNTGALPISTAGQEFIESTAAGTVPWFTVEKTSPASTHVGTASSFPPEPVLI 474
            TP   Q  T T   PI+T        T  GT         +P +T + T ++  P P   
Sbjct: 3683 TPTGTQTPTTT---PITTTTTVTPTPTPTGT--------QTPTTTPITTTTTVTPTPTPT 3731

Query: 475  STAAPVDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETTPAPRTAETELTSTNFQD 534
             T  P  +      T  P  T       T   +T  T  +  TP P   +T  T+     
Sbjct: 3732 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-VTPTPTPTGTQTPTTTPITTT 3790

Query: 535  VSLPRVEDAMSTSMSKETSSKTFSFLTSFSF-TGTESVQTVIDAEATRTALTPEITLAST 593
             ++        T     T   T + +T     TGT++  T      T    TP  T   T
Sbjct: 3791 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3850

Query: 594  VAETMLSSTITGRVYTQNTPTADGHLLTLMSTRSASTSKAPESGPTSTTDEAAHLFSSNE 653
               T +++T T       TPT  G      +  + +T+  P   PT T        ++  
Sbjct: 3851 PTTTPITTTTT----VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3906

Query: 654  TIWTSRPDQALLASMNTTTILTFVPNENFTSAFHENTTYTEYLSATTNITPLKASPEGKG 713
            T+ T  P      +  TT I T        +     T  T  ++ TT +TP   +P   G
Sbjct: 3907 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTG 3962

Query: 714  TTANDATTARYTTAVSKLTSPWFANFSIVSGTTSITNMPEFKLTTLLLKTIPMSTKPANE 773
            T     T    TT V+   +P        +GT + T  P    TT+     P  T+    
Sbjct: 3963 TQTPTTTPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 4014

Query: 774  LPLTPRETVVPSVDIISTLACIQPNFSTEESASET-----TQTEINGAIVFGGTTTPVP- 827
             P+T   TV P+     T        +T  + + T     TQT     I    T TP P 
Sbjct: 4015 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 4074

Query: 828  ----KSATTQRLNATVT---RKEATSHYLMRKSTIAAVAEVSPFSTMLEVTDESAQRVTA 880
                ++ TT  +  T T       T       + I     V+P  T       +   +T 
Sbjct: 4075 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4134

Query: 881  SVTVSSFPDIEKLSTPLDNKTATTEVRESWLLTKLVKTTPRSSYNEMTEMFNFNHTYVAH 940
            + TV+  P      TP   +T TT        T +  TT  +     T       T +  
Sbjct: 4135 TTTVTPTP------TPTGTQTPTT--------TPITTTTTVTPTPTPTGTQTPTTTPITT 4180

Query: 941  WTSETSEGISAGSPTSGSTHIFGEPLGASTTRISETSFSTTPTDRTATSL---SDGILPP 997
             T+ T      G+ T   TH    P+   TT       ST  T R+ +S    S  +L  
Sbjct: 4181 TTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLST 4240

Query: 998  QPTAAHSSATPVPVTHMFSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSST 1057
             P A   ++T  P T       +G   ++     T S P T  R  +T   S  +  +  
Sbjct: 4241 LPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQ 4300

Query: 1058 TMTTALVPPLDQTASTTIVIVPTHGDLIRTTSEATVISVRKTSMAVP------------- 1104
            T TT+   P     ST  +I  T   L    S   +  V   +   P             
Sbjct: 4301 TTTTSAWTPTPTPLSTPSIIRTT--GLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTC 4358

Query: 1105 -----SLTETPFHSLRLSTPVTAKAETTLFSTSVDTVTPSTHTLVCSKPPPDNIPP 1155
                 SL+ T       S P T     T    S  T TPS  +   SKP P   PP
Sbjct: 4359 YFVNCSLSCT-LEFYNWSCPSTPSPTPT---PSKSTPTPSKPSSTPSKPTPGTKPP 4410



 Score = 78.2 bits (191), Expect = 1e-13
 Identities = 94/364 (25%), Positives = 139/364 (38%), Gaps = 39/364 (10%)

Query: 1880 MTSWNIPTAEGSQFPISTTINVPTSNEMETETLHLVPGPLSTFTASQTGLVSKDVMAMSS 1939
            +T+ + PT   S  P STT   PT+      T    P P +T +   T   +       S
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPS 1455

Query: 1940 IPMSGIL--PNHGLSENPSLSTSLRAITSTLADVKHTFEKMTTSVTPGTTLPSILSGATS 1997
             P+S     P       P+ + S    T +      T    TT+ +P TT P     +T+
Sbjct: 1456 PPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTT 1515

Query: 1998 GSVISKSPILTWLLSSLPSGSPPATVSNAPHVMTSSTVEVSKSTFLTSDMISAHPFTNLT 2057
                +  P  T    +  + +PP T + +P   T  T   S +T   +   S  P T  T
Sbjct: 1516 ----TLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPP-TTTT 1570

Query: 2058 TLPSATMSTILTRTIPTPTLGGITTGFPTSLPMSINVTDDIVYISTHPEASSRTTITANP 2117
            T P  T  +  T T P+P     TT  PT+ P                  S  TT T  P
Sbjct: 1571 TPPPTTTPSPPTTTTPSPPTITTTTPPPTTTP------------------SPPTTTTTTP 1612

Query: 2118 RTVSHPSSFSRKTMSPSTTDHTLSVGAMPLPSSTITSSWNRIPTASSPSTLIIPKPTLDS 2177
               + PS  +   ++P T+  TL     P P  T T++     T S P+T   P P +  
Sbjct: 1613 PPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTT-PSPPI-- 1669

Query: 2178 LLNIMTTTSTVPGASFPLISTGVTYPFTATVSSPISSFFETTWLDSTPSFLSTEASTSPT 2237
                 TTT+T P  + P      + P T T S P ++    +   +  S ++T  + S T
Sbjct: 1670 -----TTTTTPPPTTTP------SSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSST 1718

Query: 2238 ATKS 2241
             T S
Sbjct: 1719 TTPS 1722



 Score = 74.3 bits (181), Expect = 2e-12
 Identities = 82/271 (30%), Positives = 112/271 (41%), Gaps = 19/271 (7%)

Query: 1979 TTSVTPGTTLPS--ILSGATSGSVISKSPILTWLLSSLPSGSPPATVSNAPHVMTSSTVE 2036
            TT+  P TT PS  I +  T     + SP  T       + SPP T  + P   T++   
Sbjct: 1444 TTTTPPPTTTPSPPISTTTTPPPTTTPSPPTT-------TPSPPTTTPSPPTTTTTTPPP 1496

Query: 2037 VSKSTFLTSDMISAHPFTNLTTLPSATMST--ILTRTIPTPTLGGITTGFPTSLPMSINV 2094
             +  +  T+  I+  P  + TTLP  T  +    T T P PT    T   PT+ P++   
Sbjct: 1497 TTTPSPPTTTPIT--PPASTTTLPPTTTPSPPTTTTTTPPPTT---TPSPPTTTPITPPT 1551

Query: 2095 TDDIVYISTHPEASSRTTITANPRTVSHPSSFSRKTMSPST-TDHTLSVGAMPLPSSTIT 2153
            +   +  +T P     TT T  P T   PS  +  T SP T T  T      P P +T T
Sbjct: 1552 STTTLPPTTTPSPPPTTTTTPPPTTT--PSPPTTTTPSPPTITTTTPPPTTTPSPPTTTT 1609

Query: 2154 SSWNRIPTASSPSTLIIPKPTLDSLLNIMTTTSTVPGASFPLISTGVTYPFTATVSSPIS 2213
            ++     T S P+T  I  PT  + L   TT S  P  +     T    P T T  SP  
Sbjct: 1610 TTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPI 1669

Query: 2214 SFFETTWLDSTPSFLSTEASTSPTATKSTVS 2244
            +   T    +TPS   T   + PT T +T S
Sbjct: 1670 TTTTTPPPTTTPSSPITTTPSPPTTTMTTPS 1700


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score =  328 bits (841), Expect = 5e-89
 Identities = 571/2259 (25%), Positives = 910/2259 (40%), Gaps = 360/2259 (15%)

Query: 238  EKSTTVSQQIDMTTP---SQITGVKPQNTAHSSTLLSQSIPIFATDYTTISYSNT--TSP 292
            E ST  +  +D +TP   S  T   P  TA  ++L + +    +T  T+I  S T  TSP
Sbjct: 1235 EASTLSTSPVDTSTPVTTSAETSSSP-TTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSP 1293

Query: 293  PLETMTAQKILKTLVDETATFAVDVLSTSSAISLPTQSISIDNTTNSMKKTKSPSSESTK 352
               T+     L T VD        V++++   S PT +      T++  + ++P +    
Sbjct: 1294 EASTL-----LTTPVDTKGP----VVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPV 1344

Query: 353  TTKMVEAMATEIFQPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFST-IESTS 411
             T +V + A  I       N  ST   T     S+ +  +  S      S  +T + S  
Sbjct: 1345 NTTLVASSAISILSTTPVDN--STPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIP 1402

Query: 412  MSTTPCLKQKSTNTGALPI--STAGQEFIESTAAGT------VPWFT------------V 451
            +STTP +  +++   A P+  ST G    E+T++ T      +P  T            V
Sbjct: 1403 VSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPV 1462

Query: 452  EKTSPASTHVGTASSFPPE---PVLISTAAPVDSVFPRNQTAFPLAT-TDMKIAFTVHSL 507
              T  A++   T S+ P +   PV+ STA    S  P   T+  ++T ++   A T   +
Sbjct: 1463 SNTPVANSEASTLSTTPVDSNSPVVTSTAVS-SSPTPAEGTSIAISTPSEGSTALTSIPV 1521

Query: 508  TLPT------RLIETTPAPRTAETELTSTNFQDVSLPRVEDAMSTSMSKETSSKTFSFLT 561
            +  T        + TTPA     T +T T  Q  S P   D   TSM   T S+  + LT
Sbjct: 1522 STTTVASSEINSLSTTPA--VTSTPVT-TYSQASSSPTTADG--TSMQTSTYSEGSTPLT 1576

Query: 562  SFSFTGTESVQTVIDAEATRTALTPEITLASTVAETMLSSTIT--GRVYTQNTPTADGHL 619
            S       S   V+ +EA   + TP  +     A T  SS+ T  G   T +TP+    L
Sbjct: 1577 SLPV----STMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPL 1632

Query: 620  LTLMSTRSASTSKAPESGPTSTTDEAAHLFSSNETIWTSRPDQALLASMNTTTILTFVPN 679
            LT +   S +   +PE+   STT        SN  + TS      ++S  T    T +P 
Sbjct: 1633 LTSIPV-STTPVASPEASTLSTTP-----VDSNSPVITSTE----VSSSPTPAEGTSMPT 1682

Query: 680  ENFTSAFHENTTYTEYLS--ATTNITPLKASPEGKGTTANDATTARYTTAVSKLTSPWFA 737
              +T      T+ T   +  A++ I+ L  +P    T    +T AR +   S+ TS    
Sbjct: 1683 STYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTS--MP 1740

Query: 738  NFSIVSGTTSITNMPEFKLTTLLLKTIPMSTKPANELPLTPRETVVP---SVDIISTLAC 794
            N +   GTT +T++P        + T P+ +  A+ L  TP +T  P   S +  S+   
Sbjct: 1741 NSTPSEGTTPLTSIP--------VSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTT 1792

Query: 795  IQ----PNFSTEESASETTQTEINGAIVFGG-----TTTPVPKSA---TTQRLNATVTRK 842
             +    P  +  E  +  T T ++  +V        +TTPV  ++   T+  ++++ T  
Sbjct: 1793 AEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPA 1852

Query: 843  EATSHYLMRKSTIAAVAEVSPFSTMLEVTDE----SAQRVTASVTVSSFPDIEKLSTPLD 898
            E TS      S  +      P ST    + E    S      S  V+++  +    T  D
Sbjct: 1853 EGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTAD 1912

Query: 899  NKTATTEVRESWL--LTKL---VKTTPRSSYNEMTEMFNFNHTYVAHWTSE-----TSEG 948
              +  T         LT +     T   S  N ++       T V  ++       T++G
Sbjct: 1913 GSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADG 1972

Query: 949  ISAGSP--TSGSTHIFGEPLGASTTRISETS-FSTTPTDRT--ATSLSDGILPPQPTAAH 1003
             S  +P  + GST +   PL  +    SE S  STTP D +  AT+ ++G   P      
Sbjct: 1973 TSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGT 2032

Query: 1004 SSATPVP---VTHMFSLPVNGSSVVAEE------------TEVTMS-EPSTLARAFSTSV 1047
            S  T  P    T +  +PV+ + VV+ E            T+VT S E S+ A A  +S+
Sbjct: 2033 SIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSM 2092

Query: 1048 LSDVSNLSSTTMT------TALVPPLDQTASTTIVIVPTHGDLIRTTS-EATVISVRKTS 1100
                 +  S  +T      T +  P   T STT V   ++  +I +T   ++ I    TS
Sbjct: 2093 TISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPV--DSNSPVITSTEVSSSPIPTEGTS 2150

Query: 1101 MAVPSLTE--TPFHSLRLSTPVTAK-AETTLFSTSVDTVTPSTHTLVCSKPPPDNIPPAS 1157
            M   + ++  TP  S+ +ST V A  A +TL +T VDT TP T++      P  +   + 
Sbjct: 2151 MQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSM 2210

Query: 1158 STHVISTTSTPEATQPISQVE--------------------ETSTYALSFPYTFSGGGV- 1196
             T   S  STP  + P+S +                      TST A S P T  G  + 
Sbjct: 2211 PTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIP 2270

Query: 1197 VASLATGTT--------------------ETSVVDETTP---SHISANKLTTSVNSHISS 1233
             ++L+ GTT                     T+ VD  TP   S  +++   T+  + + +
Sbjct: 2271 TSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPT 2330

Query: 1234 SATYRVHTPVSIQLVTSTSVLSSDKDQMTIS-------------LGKTPRTMEVTEMSPS 1280
            S +   +TP++   V++T V S +   ++ +              G +P T + T M  S
Sbjct: 2331 STSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTS 2390

Query: 1281 KNS---------------FISYSRGTPSLEMTDTGFPETTKI---SSHQTHSPSEIPLGT 1322
              S                +S    T S    DT  P TT     SS  T   + IP   
Sbjct: 2391 TYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSP 2450

Query: 1323 PSDGN--LASSPTS---------GSTQITPTLTS-------------SNTVGVHIPEMST 1358
            PS+G   LAS P S         G+   TP  TS             +    + +P  + 
Sbjct: 2451 PSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTA 2510

Query: 1359 SLGKTALPSQALTITTFLCPEKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDT 1418
            S G T L S  ++ T    PE  + S  P  +   V   V ST ++ S +  + TS   +
Sbjct: 2511 SEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPV---VTSTEISSSATSAEGTSMPTS 2567

Query: 1419 TTSSSTRISNPMDINT---TFSHLHSLRTQPEVTSVASFISESTQTFPESLSLSTAGLYN 1475
            T S  +     M ++T     S   +L T P  TS+   ++ ST+T   S S +TA   +
Sbjct: 2568 TYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIP--VTTSTET---SSSPTTAKDTS 2622

Query: 1476 DGFTVLSDRITTAFSVPNVPTMLPRESSMATSTPIYQMSSLPVNVTAF--TSKKVSDTPP 1533
               +  S+  T+  S+  + + +P  SS A++     +S+ PV+      TS   S +P 
Sbjct: 2623 MPISTPSEVSTSLTSI--LVSTMPVASSEAST-----LSTTPVDTRTLVTTSTGTSSSPT 2675

Query: 1534 IVITKSSKTMHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPATVSSDTSTRVGLFSTLLS 1593
                 S  T  PG   +P T     +   +++  N+ A T +T   DTST V   +   S
Sbjct: 2676 TAEGSSMPTSTPGERSTPLT----NILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASS 2731

Query: 1594 SVTPR--TTMTMQTSTLDVTPV--IYAGATSKNKMVSSAFTTEMIEAPSRITPTTFLSPT 1649
            S T    T+M + T +   TP+  I           +S  +T  ++    +T +T  S +
Sbjct: 2732 SPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEAS-S 2790

Query: 1650 EPTLPFVKTVPTTIMAGIVTPFVGTTA-FSPLSSKSTGAISSIPKTTFSPFLSATQQSSQ 1708
             PT   V ++PT+  +   TP        +P++S   G +S+ P  T +P  ++T+ SS 
Sbjct: 2791 SPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASS- 2849

Query: 1709 ADEATTLGILSGITNRS------LSTVNSGTGVALTDTYSRITVP-----------ENML 1751
                T  GI+  I+  S       S   S T VA ++  +  T P           E   
Sbjct: 2850 -SPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSS 2908

Query: 1752 SPTHAD--SLHTSFNIQVSPSLTSFKSASGPTKNVKTTT-NCFSSNTR-KMTSLLEKTSL 1807
            SPT A+  S+  S   +VS  LTS   ++ P    + +T +    +TR  +T+  E +S 
Sbjct: 2909 SPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSS 2968

Query: 1808 TNYATSLNTPVSYPPWTPSSATLPSLTSFVYSPHSTEAEISTPKTSPPPTSQMVEFPVLG 1867
               A   + P+S    TP     P  +  V +     +E ST   +P  TS  V      
Sbjct: 2969 PTTAEGTSMPIS----TPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPV------ 3018

Query: 1868 TRMTSSNTQPLLMTSWNIPTAEGSQFPISTTINVPTSNEMETETLHLVPGPLSTFTASQT 1927
            T  T +++ P         TAEG+  PIST     T              PL++   S T
Sbjct: 3019 TTSTEASSSP--------TTAEGTGIPISTPSEGST--------------PLTSIPVSTT 3056

Query: 1928 GLVSKDVMAMSSIPM---SGILPNHGLSENPSLSTSLRAITSTLADVKHTFEKMTTSVTP 1984
             +   +   +S+ P+   S ++ +  +S +P+ +       ST ++       +  S TP
Sbjct: 3057 PVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTP 3116

Query: 1985 GTTLPSILSGATSGSVISKSPILTWLL----------SSLPSGSPPATVSNAPHVMTSST 2034
             T+  S +S  ++  V + +P+ T             +S+P+ S P+  S     M  ST
Sbjct: 3117 VTS--SAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPT-STPSEGSTPLTYMPVST 3173

Query: 2035 VEVSKSTFLTSDMISAHPFTNLTTLPSATMSTILTRT-IPTPTLGGITTGFPTSLPMSIN 2093
            + V  S   T         T +TT   AT ST    T IPT T     T   TS+P+S  
Sbjct: 3174 MLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPL-TSVPVSNT 3232

Query: 2094 --VTDDIVYISTHPEASSRTTITANPRTVSHPSSFSRKTMSPST-TDHTLSVGAMPLPSS 2150
               + +   +ST P   S T +T +    S P +    +M  ST ++ +  + +MP+ ++
Sbjct: 3233 PVASSEASILSTTP-VDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTT 3291

Query: 2151 TITSSWNRIPTASSPSTLIIPKPTLDSLLN-------IMTTTSTVPGASFPLISTGVTYP 2203
            T+ SS      +++P+    P  T     +           TST    S PL  T +++ 
Sbjct: 3292 TVASS-ETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPL--TNMSFS 3348

Query: 2204 FTATVSSPISSFFETTWLDSTPSFLSTEASTSPTATKST 2242
             T  VSS  S+   T    STP   STEAS SPT  + T
Sbjct: 3349 TTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGT 3387



 Score =  319 bits (818), Expect = 2e-86
 Identities = 556/2237 (24%), Positives = 880/2237 (39%), Gaps = 312/2237 (13%)

Query: 231  PENMTIQEKSTTVSQQIDMTTPSQITGVKPQNTAHSSTLLSQSIPIFA--TDYTTISYSN 288
            P   +I   +TTV+     T  + +   +   T +S    + S P  A  T   T +YS 
Sbjct: 1926 PPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQ---ASSSPTTADGTSMPTPAYSE 1982

Query: 289  TTSPPLETMTAQKILKTLV--DETATFAVDVLSTSSAISLPTQSISIDNTTNSMKKTKSP 346
             ++P    +T+  +  TLV   E +T +   + TS+  +  T+  S   T        S 
Sbjct: 1983 GSTP----LTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTST 2038

Query: 347  SSESTKTTKMVEAMATEIFQPPTPSNFLSTSRF-TKNSVVSTTSAIKSQSAVTKTTSLFS 405
             SE  +TT +     +      +  N LST+   +K  V ++T A  S +A   + ++ +
Sbjct: 2039 PSE--RTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISA 2096

Query: 406  TIESTSMSTTPCLKQKSTNTGALPISTAGQEFIESTAAGTVPWFTVEKTSPASTHVGTAS 465
              E + + T+            +P+ST      E++   T P   V+  SP  T    +S
Sbjct: 2097 PSEGSPLLTS------------IPLSTTPVASPEASTLSTTP---VDSNSPVITSTEVSS 2141

Query: 466  S-FPPEPVLISTAAPVDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETTPAPRTAE 524
            S  P E   + T+   D   P   T+ P++TT   +A +  S    T +  +TP   + E
Sbjct: 2142 SPIPTEGTSMQTSTYSDRRTPL--TSMPVSTT--VVASSAISTLSTTPVDTSTPVTNSTE 2197

Query: 525  TELTSTNFQDVSLPRVEDAMS----TSMSKETSSKTFSFLTSFSFTGTE-SVQTVIDAEA 579
               + T  +  S+P    +      TSM   T     S  ++ S T  + S       EA
Sbjct: 2198 ARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEA 2257

Query: 580  TRTALTPEITL--ASTVAE--TMLSS-------TITGRVYTQNTPTADGHLLTLMSTRSA 628
            T +  T E T    ST++E  T L+S            V T +T   D +     ST ++
Sbjct: 2258 TSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEAS 2317

Query: 629  STSKAPE--SGPTSTTDEAAHLFSSNETIWTSRPDQALLASMNTTTILTF-----VPNEN 681
            S     E  S PTST+ E       N  +        ++AS  T+T+ T       P   
Sbjct: 2318 SPPPTAEGTSMPTSTSSEG------NTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTT 2371

Query: 682  FTSAFHENTTYTE-------YLSATTNIT-------PLKASPEGKGTTANDATTARYTTA 727
            ++ A    TT  +       Y   +T +T       P+ +S     +T    T+   TT+
Sbjct: 2372 YSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTS 2431

Query: 728  VSKLTSPWFANFSIV------SGTTSITNMPEFKLTTLLLKTIPMSTKP----------- 770
                +SP  A  + +       GTT + +MP      +  +   +ST P           
Sbjct: 2432 TEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTST 2491

Query: 771  -ANELPLTPRETVVP-------SVDIISTLACIQPNFSTEESASETTQTEINGAIVFGGT 822
             A+  P T  + VVP       S  + S      P  S E S   TT  + N  +V   T
Sbjct: 2492 EASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVV---T 2548

Query: 823  TTPVPKSATTQRLNATVTRKEATSHYLMRKSTIAAVAEVSPFSTMLEVTD-ESAQRVTAS 881
            +T +  SAT+    +  T   +     +R   ++     S  ++ L  T  +++  VT S
Sbjct: 2549 STEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTS 2608

Query: 882  VTVSSFPDIEK-----LSTPLDNKTATTEVRESWLLTKLVKTTPRSSYNEMTEMFNFNHT 936
               SS P   K     +STP +  T+ T +        LV T P +S    +E    + T
Sbjct: 2609 TETSSSPTTAKDTSMPISTPSEVSTSLTSI--------LVSTMPVAS----SEASTLSTT 2656

Query: 937  YVAHWTSETSEGISAGSPTSGSTHIFGEPLGASTTRISETSFSTTPTDRTATSLSDGILP 996
             V   T  T+   ++ SPT+      G  +  ST    E S   T    + T L++    
Sbjct: 2657 PVDTRTLVTTSTGTSSSPTTAE----GSSMPTSTP--GERSTPLTNILVSTTLLANSEAS 2710

Query: 997  PQPTAAHSSATPVPVTHMFSLPVNGSSVVAEETEVTMSEPS---TLARAFSTSVLSDVSN 1053
               T    ++TPV      S   + S   AE T + +S PS   T   +   S L   S+
Sbjct: 2711 TLSTTPVDTSTPVTT----SAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASS 2766

Query: 1054 LSSTTMTTALVPPLDQTASTTIVIVPTHGDLIRTTSEATVISVRKTSMAVPSLTETPFHS 1113
             +ST  TTA+   +  T ST              +S  T   V     + PS T TP  S
Sbjct: 2767 EASTVSTTAVDTSIPVTTST------------EASSSPTTAEVTSMPTSTPSETSTPLTS 2814

Query: 1114 LRLS-TPVTAKAETTLFSTSVDTVTPSTHTLVCSKPPPDN---IPPASSTHVIST--TST 1167
            + ++ TPV +    TL +T VDT TP T +   S  P      + P S+    ST  TS 
Sbjct: 2815 MPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSI 2874

Query: 1168 PEATQPISQVE----ETSTYALSFPYTFSGGGVVASLATGTTETSVVDETTPSHISANKL 1223
            P +T P++  E     T+    S P T S  G   S +  T E + +  +TPS +S    
Sbjct: 2875 PVSTTPVASSEASTLSTTPVDTSIPVTTSTEG---SSSPTTAEGTSMPISTPSEVSTPLT 2931

Query: 1224 TTSVN------SHISSSATYRV--HTPVSIQLVTSTSVLSSDKDQMTISLGKTPRTMEVT 1275
            +  V+      S  S+ +T  V   TPV+     S+S  +++   M IS     RT  +T
Sbjct: 2932 SILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRT-PLT 2990

Query: 1276 EMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSPSE---IPLGTPSDGN--LAS 1330
             MS S     S    T S    DT  P TT   +  + + +E   IP+ TPS+G+  L S
Sbjct: 2991 SMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTS 3050

Query: 1331 SPTSGSTQITPTLTSSNTVGVHIPEMSTSLGKTALPSQALTITTFLCPEKESTSALPAYT 1390
             P S             T  V IPE ST L  T + S +  +T        ST    + T
Sbjct: 3051 IPVS-------------TTPVAIPEAST-LSTTPVDSNSPVVT--------STEVSSSPT 3088

Query: 1391 PRTVEMIVNSTYVTHSVSY-GQDTSFVDTTTSS-STRISNPMDINT---TFSHLHSLRTQ 1445
            P     +  STY   S    G   S    T+S+ ST  + P+D +T   T +  HS  T 
Sbjct: 3089 PAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTT 3148

Query: 1446 PEVTSVASFISESTQTFPESLSLSTAGLYNDGFTVLSDRITTAFSVPNVPTMLP-RESSM 1504
             E TS+ +       T    + +ST         V+S   +T  + P V T  P   S+ 
Sbjct: 3149 SEGTSMPTSTPSEGSTPLTYMPVST-------MLVVSSEDSTLSATP-VDTSTPVTTSTE 3200

Query: 1505 ATSTPIYQMSSLPVN-----VTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTATSGPM 1559
            ATS+   + +S+P +     +T  TS  VS+TP      S  +  P    +P T ++   
Sbjct: 3201 ATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTST--- 3257

Query: 1560 SEMSSIPVNNSAFTPATVSSDTSTRVGLFSTLLSSVTPRTTMTMQTSTLDV-TPVIYAGA 1618
               SS P       P +  S+ ST +       ++V    T T+ T+  D  TPV     
Sbjct: 3258 EASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQ 3317

Query: 1619 TSKNKMVSSAFTTEMIEAPSRITPTTFLS-PTEPTLPFVKTVPTTIMAGIVTPFVGTT-- 1675
             S +  ++   +          TP T +S  T P +    +  +T      TP   +T  
Sbjct: 3318 ASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEA 3377

Query: 1676 AFSPLSSKSTGAISSIPKTTFSPFLSATQQSSQADEATTLGILSGITNRSLSTVNSGTGV 1735
            + SP +++ T   +S P    +P  S          +TT  + S +   S + V+S T V
Sbjct: 3378 SLSPTTAEGTSIPTSSPSEGTTPLASMPV-------STTPVVSSEVNTLSTTPVDSNTLV 3430

Query: 1736 AL-TDTYSRITVPENMLSPTHADSLHTS----FNIQVSPSLTSFKSASGPTKNVKTTTNC 1790
               T+  S  T+ E    PT   S  ++      +  +P  +S  S    T    +T   
Sbjct: 3431 TTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVT 3490

Query: 1791 FSSNTRKMTSLLEKTSL-TNYATSLNTPVSYPP--WTPSSATLPSLTSFVYSPHSTEAEI 1847
             SS T    +  E TS+ T+ A   +TP++  P   TP +++  S  S      +T    
Sbjct: 3491 TSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTS 3550

Query: 1848 STPKTSPPPTSQMVEFPVLGTRMTSSNTQPLLMTSWNIPTAEGSQFPISTTINVPTSNEM 1907
            S+  +S P T Q+    +      SS+   +L++S  + ++E S     +T +V  S  +
Sbjct: 3551 SSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEAST---PSTPSVDRSTPV 3607

Query: 1908 ETETLHL---VPGPLSTFTASQTGLVSKDVMAMSSIPMSGILPNHGLSENPSLSTSLRAI 1964
             T T       P  + T   S    VS  +  M     S  +   G +    + TS   I
Sbjct: 3608 TTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVI 3667

Query: 1965 TSTLADVKHTFEKMTTSVTP-GTTLPSILSGATSGSVISKSPILTWLLSSLPSG--SPPA 2021
            TST        +  ++ VTP GTT+P I + +   + ++  P+ T  ++S      S P+
Sbjct: 3668 TST--------QVSSSPVTPEGTTMP-IWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPS 3718

Query: 2022 TVSNAPHVMTSSTVEVSKSTFLTSDMISAHPFTNLTTLPSATMSTILTRTIP-------- 2073
             V++ P  +T+ST  +S S  L S  +S      ++TL +    TIL  T P        
Sbjct: 3719 VVTSTP--VTTSTEAISSSATLDSTTMSVSMPMEISTLGT----TILVSTTPVTRFPESS 3772

Query: 2074 TPTLGGITTGFP-------TSLPMSINVTDDIVYISTHPEASSRTTITANPRTVSHPSSF 2126
            TP++  + T          +S P ++  T  +   +T   ++  TT+  +P +V  PS  
Sbjct: 3773 TPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEA 3832

Query: 2127 SRKTMSPSTTDHTL----SVGAMPLPSS------TITSSWNR----------IPTASSPS 2166
            S  +  P  T   L      G+  +P+       +ITS  +           +PT S P 
Sbjct: 3833 STLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPT-SFPG 3891

Query: 2167 TLIIPKPTLDSLLNIMTTTSTVPGASFPLIST------------GVTY--PFTATVSSPI 2212
              I   P LD+      +T T    + P+ +T            G T   P T   SS  
Sbjct: 3892 ASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTA 3951

Query: 2213 SSFFETTWLDSTPSFLSTEASTSPTATKSTVSFYNVEMSFSVFVEEPRIPITSVINEFTE 2272
              F  TT   STP   STE +T  T++ ST + ++    F+        P+T V      
Sbjct: 3952 DVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAP 4011

Query: 2273 NSLNSIFQNSEFSLATL 2289
            ++  +  +    S +TL
Sbjct: 4012 STPRTTSRGCTTSASTL 4028



 Score =  317 bits (813), Expect = 9e-86
 Identities = 538/2174 (24%), Positives = 882/2174 (40%), Gaps = 315/2174 (14%)

Query: 240  STTVSQQIDMTTPSQITGVKPQNTAHSSTLLSQS-IPIFATDYTTISYSNTTSPPLETMT 298
            STT     + +T S  T V   +   +ST +S S IP   T   T +YS+  +P    +T
Sbjct: 2110 STTPVASPEASTLST-TPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTP----LT 2164

Query: 299  AQKILKTLVDETA--TFAVDVLSTSSAISLPTQSISIDNTTNSMKK-TKSPSSESTKTTK 355
            +  +  T+V  +A  T +   + TS+ ++  T++ S   T+      T +PS  ST  T 
Sbjct: 2165 SMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTS 2224

Query: 356  MVEAMATEIFQPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFSTIESTSMSTT 415
            M       +   P  ++  ST   T    V T++ + +    T+ TS  +T E TS+ T+
Sbjct: 2225 M------PVSTMPVVTSEASTLSATP---VDTSTPVTTS---TEATSSPTTAEGTSIPTS 2272

Query: 416  PCLKQKSTNTGALPISTAGQEFIESTAAGTVPWFTVEKTSPASTHVGTASSFPPEPVLIS 475
              L + +T   ++P+S      + ++   T+    V+  +P +T   T +S PP P    
Sbjct: 2273 T-LSEGTTPLTSIPVS---HTLVANSEVSTLSTTPVDSNTPFTT--STEASSPP-PTAEG 2325

Query: 476  TAAPVDSVFPRNQ--TAFPLATTDMKIAFTVHSLTLPTRLIETTPAPRTAETELTSTNFQ 533
            T+ P  +    N   T  P++TT +         +  T  + TTPA  +      +T  Q
Sbjct: 2326 TSMPTSTSSEGNTPLTRMPVSTTMVA--------SFETSTLSTTPADTSTPV---TTYSQ 2374

Query: 534  DVSLPRVEDAMSTSMSKETSSKTFSFLTSFSFTGTESVQTVIDAEATRTALTPEITLAST 593
              S P   D   TSM   T S+  + LTS       S   V+ +EA+  + TP  T    
Sbjct: 2375 AGSSPTTAD--DTSMPTSTYSEGSTPLTSVPV----STMPVVSSEASTHSTTPVDTSTPV 2428

Query: 594  VAETMLSSTITGRVYTQNTPTADGHLLTLMSTRSASTSK--APESGPTSTT--DEAAHLF 649
               T  SS+ T    T    +      T +++   ST+   + E+G  STT  D +  + 
Sbjct: 2429 TTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMT 2488

Query: 650  SSNETIWTSRPDQALLASMNT----TTILTFVPNENFTSAFHENTTY--TEYLSATTNIT 703
            +S E   +    + ++  ++T    +T+LT +P      A  E +T   T   S +  +T
Sbjct: 2489 TSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVT 2548

Query: 704  PLKASPEGKGTTANDATTARYTTAVSKLTSPWFANFSIVSGTTSITNMPEFKLTTLLLKT 763
              + S            T+ Y+   + L S   +   + S   S  +      TT +  +
Sbjct: 2549 STEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLS------TTPVDTS 2602

Query: 764  IPMSTKP-ANELPLTPRETVVP-------SVDIISTLACIQPNFSTEESASETTQTEING 815
            IP++T    +  P T ++T +P       S  + S L    P  S+E S   TT  +   
Sbjct: 2603 IPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRT 2662

Query: 816  AIVFGGTTTPVPKSATTQRLNATVTRKEATS-HYLMRKSTIAAVAEVSPFSTMLEVTDES 874
             +     T+  P +A    +  +   + +T    ++  +T+ A +E S  ST      ++
Sbjct: 2663 LVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLST---TPVDT 2719

Query: 875  AQRVTASVTVSSFPDIE-----KLSTPLDNKTATTEVRESWLLTKLVKTTPRSSYNEMTE 929
            +  VT S   SS P        ++STP D  T  T +        LV T P +S    +E
Sbjct: 2720 STPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSI--------LVSTLPVAS----SE 2767

Query: 930  MFNFNHTYVAHWTSETSEGISAGSPTSGSTHIFGEPLGASTTRISETSFSTTPTDRTATS 989
                + T V      T+   ++ SPT+         +  ST   + T  ++ P + T  +
Sbjct: 2768 ASTVSTTAVDTSIPVTTSTEASSSPTTAEV----TSMPTSTPSETSTPLTSMPVNHTPVA 2823

Query: 990  LSD-GILPPQPTAAHSSATPVPV-THMFSLPVNGSSVVAEETEVTMSEPSTLARAFSTSV 1047
             S+ G L   P     ++TPV   T   S P     +V   +  T SE STL  +   S 
Sbjct: 2824 SSEAGTLSTTPV---DTSTPVTTSTKASSSPTTAEGIVVPIS--TASEGSTLLTSIPVST 2878

Query: 1048 LSDVSNLSSTTMTTALVPPLDQTASTTIVIVPTHGDLIRTTSEATVISVRKTSMAVPSLT 1107
                S+ +ST  TT    P+D +   T     T G    TT+E T + +     + PS  
Sbjct: 2879 TPVASSEASTLSTT----PVDTSIPVT---TSTEGSSSPTTAEGTSMPI-----STPSEV 2926

Query: 1108 ETPFHSLRLST-PVTAKAETTLFSTSVDTVTPSTHTLVCSKPP--------PDNIPPASS 1158
             TP  S+ +ST PV     +TL +T VDT TP T +   S  P        P + P    
Sbjct: 2927 STPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERR 2986

Query: 1159 THVISTTSTPEATQPISQVEE---------------TSTYALSFPYTFSGGGV-VASLAT 1202
            T +   TS   +T P++  E                TST A S P T  G G+ +++ + 
Sbjct: 2987 TPL---TSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSE 3043

Query: 1203 GTTE-TSVVDETTPSHI--SANKLTTSVNSHISSSATYRVHTPVSIQLVTSTSVLSSDKD 1259
            G+T  TS+   TTP  I  ++   TT V+S+          +PV      S+S   ++  
Sbjct: 3044 GSTPLTSIPVSTTPVAIPEASTLSTTPVDSN----------SPVVTSTEVSSSPTPAEGT 3093

Query: 1260 QMTISL---GKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSPS 1316
             M IS    G TP T      +P  +S IS    TP     DT  P TT   +H + + S
Sbjct: 3094 SMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTP----VDTSTPVTTSTEAHSSPTTS 3149

Query: 1317 E---IPLGTPSDGN--------------------LASSPTSGSTQITPTL--TSSNTV-G 1350
            E   +P  TPS+G+                    L+++P   ST +T +   TSS T  G
Sbjct: 3150 EGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEG 3209

Query: 1351 VHIPEMSTSLGKTALPSQALTITTFLCPEKE--STSALPAYTPRTVEMIVNSTYVTHSVS 1408
              IP  + S G T L S  ++ T     E    ST+ + + TP T      ST  + S  
Sbjct: 3210 TSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTT-----STEASSSPP 3264

Query: 1409 YGQDTSFVDTTTSSSTRISNPMDINTTF---SHLHSLRTQPEVTSV-ASFISESTQTFP- 1463
              + TS   +T S  +     M ++TT    S   +L T P  TS   +  S+++ + P 
Sbjct: 3265 TAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPI 3324

Query: 1464 -ESLSLSTAGLYNDGFTVLSDRITTAFSVPNVPTMLPRESSMATSTPIYQMSSLPVNVTA 1522
             +  S+ T+  Y++G T L++    +FS   V   +  E+S  ++TP+   + +  +  A
Sbjct: 3325 ADGTSMPTS-TYSEGSTPLTNM---SFSTTPV---VSSEASTLSTTPVDTSTPVTTSTEA 3377

Query: 1523 FTSKKVSDTPPIVITKSSKTMHPGCLKSPCTAT---SGPMSEMSSIPVNNSAFTPATVSS 1579
              S   ++   I  +  S+   P     P + T   S  ++ +S+ PV+++     +  +
Sbjct: 3378 SLSPTTAEGTSIPTSSPSEGTTP-LASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEA 3436

Query: 1580 DTSTRVGLFSTLLSSVTPRTTMTMQTSTLDVTPVIYAGATSKNKMVSSAFTTEMIEAPSR 1639
             +S  +   ++L +S T   +  +    L  TPV  + A        S  +T  ++    
Sbjct: 3437 SSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEA--------STLSTTPVDTS-- 3486

Query: 1640 ITPTTFLSPTE--PTLPFVKTVPTTIMAGIVTPFVGT-TAFSPLSSKSTGAISSIPKTTF 1696
             TP T  SPT   PT   V ++PT+      TP      + +P++S     +S+ P  + 
Sbjct: 3487 -TPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDS- 3544

Query: 1697 SPFLSATQQSSQADEATTLGILSGITNRSLSTVNSGTGVALTDTYSRITVPENMLSPTHA 1756
            + F++++ Q+S +           +T   +ST + G+    T   S   V  +  S    
Sbjct: 3545 NTFVTSSSQASSSPATLQ------VTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPST 3598

Query: 1757 DSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLLEKTSLTNYATSLNT 1816
             S+  S     +P  TS +S S PT     T    + +       +   S T+   S   
Sbjct: 3599 PSVDRS-----TPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAG 3653

Query: 1817 PVSYPPWTPSSATLPS--LTSFVYSPHSTEAEISTPKTSPPPTSQMVEFPVLGTRMTSSN 1874
              S  P   S+  + S  ++S   +P  T   I TP     P + M   PV  TR+TSS 
Sbjct: 3654 TASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTM---PVSTTRVTSSE 3710

Query: 1875 ----TQPLLMTSWNIPTA----EGSQFPISTTINVPTSNEMET--ETLHLVPGPLSTFTA 1924
                + P ++TS  + T+      S    STT++V    E+ T   T+ +   P++ F  
Sbjct: 3711 GSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPE 3770

Query: 1925 SQTGLVSKDVMAMS----SIPMSGILPNHGLSENPSLSTSLRAITSTLA-----DVKHTF 1975
            S T  +     +MS    S   S      G +  P  +TS R+   T        V    
Sbjct: 3771 SSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPS 3830

Query: 1976 EKMTTSVTPGTTLPSILSGATSGSVI---------------SKSPILTWLLSS-LPSGSP 2019
            E  T S  PG T   +L+   +GS                   +P+ T L+S+ LP+  P
Sbjct: 3831 EASTLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFP 3890

Query: 2020 PATVSNAPHVMTSSTVEVSKSTFLTSDM-----ISAHPFTNLTT------LPSATMSTIL 2068
             A++++ P + TS+T   S  T  T  +     IS    T  +T      +PS  +++  
Sbjct: 3891 GASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSST 3950

Query: 2069 TRTIPTPTLGGITTGFPTSLPM---SINVTDDIVYISTHPEASSRTTITA---------- 2115
                P  T G ++T   TS  +   S + +      ST  E ++    TA          
Sbjct: 3951 ADVFPATT-GAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMST 4009

Query: 2116 ---NPRTVSHPSSFSRKTMSPSTTDHT-LSVGAMPLPSSTITSSWNRIPTASSPSTLIIP 2171
                PRT S   + S  T+S ++T HT  SV   P+  S+ +S  + I + + P T    
Sbjct: 4010 APSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTF--- 4066

Query: 2172 KPTLDSLLNIMTTTSTVPGASFPLISTGVTYPFTATVSSPISSFFETTWLDSTPSFLSTE 2231
             P   S     + +ST          T  T P T T S P      TT    T + + + 
Sbjct: 4067 PPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPT----VTTTAVPTNTTIKSN 4122

Query: 2232 ASTSPTATKSTVSF 2245
             +++PT  ++T  F
Sbjct: 4123 PTSTPTVPRTTTCF 4136



 Score =  316 bits (810), Expect = 2e-85
 Identities = 553/2241 (24%), Positives = 906/2241 (40%), Gaps = 305/2241 (13%)

Query: 231  PENMTIQEKSTTVSQQIDMTTPSQITGVKPQNTAHSSTLLSQSIPIFATDYTTISYSNTT 290
            P   T    ST VS  +   + +      P +   S+T L+ S    +   T    S  T
Sbjct: 978  PSEGTTPLTSTPVSHTLVANSEASTLSTTPVD---SNTPLTTSTEASSPPPTAEGTSMPT 1034

Query: 291  SPPLE---TMTAQKILKTLV--DETATFAVDVLSTSSAISLPTQSISIDNTTNSMKKTKS 345
            S P E    +T   +  T+V   ET+T +     TS+ ++  +Q+ S   T +      S
Sbjct: 1035 STPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTS 1094

Query: 346  PSSESTKTTKMVEAMATEIFQPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKT--TSL 403
              SE           +T +   P  +  + +S   + S +STT    S    T T  +S 
Sbjct: 1095 TYSEG----------STPLTSVPVSTRLVVSS---EASTLSTTPVDTSIPVTTSTEASSS 1141

Query: 404  FSTIESTSMSTTPCLKQKSTNTGALPISTAGQEFIESTAAGTVPWFTVEKTSPASTHVGT 463
             +T E TS+ T+P   + +T   ++P+ST     + S+ A T+    V+  +  +T   T
Sbjct: 1142 PTTAEGTSIPTSP-PSEGTTPLASMPVSTT---LVVSSEANTLSTTPVDSKTQVAT--ST 1195

Query: 464  ASSFPPEPVLISTAAPVDSVFPRNQ--TAFPLATTDMKIAFTVHSLTLPTRLIET-TPAP 520
             +S PP P    T+ P  +   R+   T+ P+  T +    +  + TL T  ++T TP  
Sbjct: 1196 EASSPP-PTAEVTSMPTSTPGERSTPLTSMPVRHTPVA---SSEASTLSTSPVDTSTPVT 1251

Query: 521  RTAETELTSTNFQDVSLPRVEDAMSTSMSKETSSKTFSFLTSFSFTGTESVQTVIDAEAT 580
             +AET  + T  +  SLP       TS + E S+   S   S +   +    T++     
Sbjct: 1252 TSAETSSSPTTAEGTSLP-------TSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVD 1304

Query: 581  R---TALTPEITLASTVAE--TMLSSTIT-GRV----YTQNTPTADGHLLTLMST----R 626
                   + E++ + T AE  +M +ST + GR        NT       ++++ST     
Sbjct: 1305 TKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDN 1364

Query: 627  SASTSKAPESGPTSTTDEAAHLFSSNET----------IWTSRPDQALLASMNTTTILTF 676
            S   + + E+  + TT E   + +SN +          + T+    +  ++++ T + T 
Sbjct: 1365 STPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTS 1424

Query: 677  VPNENFTSAFHENTTYTEYLSATTNI-----TPLKASPEGKGTTANDATTARYTTAVSKL 731
             P      A    TT  E +S  T+      TPLK+ P      AN   +   TT V   
Sbjct: 1425 TPGTTSAEATSSPTT-AEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDS- 1482

Query: 732  TSPWFANFSIVS------GTTSITNMP---EFKLTTLLLKTIPMSTKPANELPLTPRETV 782
             SP   + ++ S      GT+   + P      LT++ + T  +++   N L  TP  T 
Sbjct: 1483 NSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTS 1542

Query: 783  VPSVDIISTLACIQPNFSTEESASETTQTEINGAIVFGGTTTPVPKSATTQRLNATVTRK 842
             P    ++T +    + +T +  S  T T   G+     T+ PV           T++  
Sbjct: 1543 TP----VTTYSQASSSPTTADGTSMQTSTYSEGSTPL--TSLPVSTMLVVSSEANTLSTT 1596

Query: 843  EATSHYLMRKSTIAAVAEVSPFSTMLEVTDESAQRVTASVTVS----SFPDIEKLS-TPL 897
               S   +  ST A+ +  +  S+M   T      +  S+ VS    + P+   LS TP+
Sbjct: 1597 PIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPV 1656

Query: 898  DNKT---ATTEVRESWLLTKLVKTTPRSSYNEMTEMFNFNHTYVAHWTSETSEGISAGSP 954
            D+ +    +TEV  S         TP    +  T  +    T +   T  T+   S+   
Sbjct: 1657 DSNSPVITSTEVSSS--------PTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAIS 1708

Query: 955  TSGSTHIFGEPLGASTTRISETSFSTTPTDRTATSL-----SDGILPPQPTAAHSSATPV 1009
            T  +T     P+  ST   + T   ++PT    TS+     S+G  P   T+   S TPV
Sbjct: 1709 TLSTT-----PVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTP--LTSIPVSTTPV 1761

Query: 1010 ---PVTHMFSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSD-VSNLSSTTMTTALVP 1065
                 + + + P++ S+ V   TE T S  +    +  TS LS+ ++ L+ST ++  LV 
Sbjct: 1762 LSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVA 1821

Query: 1066 PLD-QTASTT------IVIVPTHGDLIRTTSEATVISVRKTSMAVPSLTETPFHSLRL-- 1116
              +  T STT       V+  T      T +E T I+    S    +LT  P  +  +  
Sbjct: 1822 NSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVAS 1881

Query: 1117 -------------STPVTAKAETTLFSTSVDTVTPSTHTLVCSKPPPDNIPPASST---- 1159
                         STPVT  A+ +   T+ D  +  T T    +PP  +IP +++T    
Sbjct: 1882 SETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASS 1941

Query: 1160 --HVIST----TSTPEATQPISQVEETSTYALSFPY-TFSGGG-----------VVASLA 1201
              + +ST    T TP  T   +    T+    S P   +S G            +V S  
Sbjct: 1942 EINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSE 2001

Query: 1202 TGTTETSVVDETTPSHIS---ANKLTTSVNSHISSSATYRVHTPVSIQLVTSTSVLSSDK 1258
              T  T+ VD +TP+  S   ++  TT+  + I +S      TP++   V++T V+SS+ 
Sbjct: 2002 ASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEG 2061

Query: 1259 DQMTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSPSEI 1318
            +  T+S        +VT  S   +S  +    + ++     G P  T I    T      
Sbjct: 2062 N--TLSTTPVDSKTQVTN-STEASSSATAEGSSMTISAPSEGSPLLTSIPLSTT------ 2112

Query: 1319 PLGTPSDGNLASSPTSGSTQITPTLTSSNTVGVHIPEMSTSLGKTALPSQALTITTFLCP 1378
            P+ +P    L+++P   +   +P +TS+      IP   TS+  +    +   +T+   P
Sbjct: 2113 PVASPEASTLSTTPVDSN---SPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSM--P 2167

Query: 1379 EKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINTTFSH 1438
               +  A  A +  +   +  ST VT+S    +  S   T+  +S   S P + +T F+ 
Sbjct: 2168 VSTTVVASSAISTLSTTPVDTSTPVTNST---EARSSPTTSEGTSMPTSTPSEGSTPFTS 2224

Query: 1439 LHSLRTQPEVTSVASFISESTQTFPESLSLSTAGLYNDGFTVLSDRITTAFSVPNVP-TM 1497
            +  + T P VTS AS +S +       ++ ST    +      +   T+  S    P T 
Sbjct: 2225 M-PVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTS 2283

Query: 1498 LPRESSMATSTPIYQMSSLPV--NVTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTAT 1555
            +P   ++  ++ +  +S+ PV  N    TS + S  PP     S  T       +P T  
Sbjct: 2284 IPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRM 2343

Query: 1556 SGPMSEMSSIPVNNSAFTPATVSSDTSTRVGLFSTLLSSVTPRTTMTMQTSTLD--VTPV 1613
                + ++S   +  + TPA    DTST V  +S   SS T     +M TST     TP+
Sbjct: 2344 PVSTTMVASFETSTLSTTPA----DTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPL 2399

Query: 1614 IYAGATSKNKMVSSAFT--TEMIEAPSRITPTTFLSPTEPTLPFVKTVPTTIMAGIVTPF 1671
                 ++   + S A T  T  ++  + +T +T  S + PT     ++PT+  +   TP 
Sbjct: 2400 TSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEAS-SSPTTAEGTSIPTSPPSEGTTPL 2458

Query: 1672 VG-TTAFSPLSSKSTGAISSIPKTTFSPFLSATQQSSQADEATTLGILSGITNRSLSTVN 1730
                 + +P+ S   G +S+ P  T +P  ++T+ SS    A  + +        +ST +
Sbjct: 2459 ASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVV-------PISTAS 2511

Query: 1731 SGTGVALTDTYSRITV--PE-NMLSPTHADS-LHTSFNIQVSPSLTSFKSASGPTKNV-- 1784
             G+ +  +   S   V  PE + LS T  DS      + ++S S TS +  S PT     
Sbjct: 2512 EGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSE 2571

Query: 1785 -KTTTNCFSSNTRKMTSLLEKTSLTNYATSLNTPVSYPPWTPSSATLPSLTSFVYSPHST 1843
              T       +T+ + S  E ++L+      + PV+    T SS T    TS    P ST
Sbjct: 2572 GSTPLRSMPVSTKPLAS-SEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSM---PIST 2627

Query: 1844 EAEISTPKTSPPPTSQMVEFPVLGTRMTSS-NTQPLLMTSWNI----PTAEGSQFPIS-- 1896
             +E+ST  TS   ++  V      T  T+  +T+ L+ TS        TAEGS  P S  
Sbjct: 2628 PSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTP 2687

Query: 1897 -------TTINVPTSNEMETETLHLVPGPLSTFT-------ASQTGLVSKDVMAMSSIPM 1942
                   T I V T+    +E   L   P+ T T       AS +   ++      S P 
Sbjct: 2688 GERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPS 2747

Query: 1943 SGILPNHGL---------SENPSLS-----TSLRAITSTLADVKHTFEKMTT--SVTPGT 1986
             G  P   +         SE  ++S     TS+   TST A    T  ++T+  + TP  
Sbjct: 2748 DGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSE 2807

Query: 1987 TLPSILSGATSGSVISKSPILTWLLSSLPSGSPPAT---VSNAPHVMTSSTVEVSK---- 2039
            T   + S   + + ++ S   T   + + + +P  T    S++P       V +S     
Sbjct: 2808 TSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEG 2867

Query: 2040 STFLTSDMISAHPF-----TNLTTLPSATMSTILTRT----IPTPTLGGITTGFPTSLPM 2090
            ST LTS  +S  P      + L+T P  T   + T T     PT   G   T  P S P 
Sbjct: 2868 STLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEG---TSMPISTPS 2924

Query: 2091 SINVTDDIVYISTHPEASS------------RTTITANPRTVSHPSSFSRKTMSPSTTDH 2138
             ++     + +ST P A S            RT +T +    S P++    +M  ST   
Sbjct: 2925 EVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGE 2984

Query: 2139 ------TLSVGAMPLPSSTITSSWNRIP----TASSPSTLIIPKPTLDSLLNIMTTTSTV 2188
                  ++SV  MP+ SS   S+ +R P    T  + ST     PT      I    ST 
Sbjct: 2985 RRTPLTSMSVSTMPVASSE-ASTLSRTPADTSTPVTTSTEASSSPTTAEGTGI--PISTP 3041

Query: 2189 PGASFPLISTGVTYPFTATVSSPISSFFETTWLDS-TPSFLSTEASTSPTATKST---VS 2244
               S PL S  V+   T  V+ P +S   TT +DS +P   STE S+SPT  + T   +S
Sbjct: 3042 SEGSTPLTSIPVS---TTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPIS 3098

Query: 2245 FYNVEMSFSVFVEEPRIPITS 2265
             Y+   +    V     P+TS
Sbjct: 3099 TYSEGSTPLTGVPVSTTPVTS 3119



 Score =  312 bits (800), Expect = 3e-84
 Identities = 565/2223 (25%), Positives = 912/2223 (41%), Gaps = 303/2223 (13%)

Query: 238  EKSTTVSQQIDMTTPSQITGVKPQNTAHSSTLLSQSIPIFATDYTTISYSNTTSPPLETM 297
            E ST  +  +D  TP        + T+ S+T    S+P       T +Y+  ++P    +
Sbjct: 645  EASTLSTTPVDSNTP---VTTSTEATSSSTTAEGTSMP-------TSTYTEGSTP----L 690

Query: 298  TAQKILKTLV--DETATFAVDVLSTSSAISLPTQSISIDNTTN-SMKKTKSPSSESTKTT 354
            T+  +  TLV   E +T +   + TS+ ++  T++ S   T + +   T +PS  ST  T
Sbjct: 691  TSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLT 750

Query: 355  KMVEAMATEIFQPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFS--TIESTSM 412
             M           P     L++S   + S +STT    S    T T +  S  T E TSM
Sbjct: 751  SM-----------PVSKTLLTSS---EASTLSTTPLDTSTHITTSTEASCSPTTTEGTSM 796

Query: 413  S-TTPCLKQKSTNTGALPISTAGQEFIESTAAGTVPWFTVEKTSPASTHVGTASS-FPPE 470
              +TP   + S    ++P+S       E++   T P   V+  SP +T    +SS  P E
Sbjct: 797  PISTP--SEGSPLLTSIPVSITPVTSPEASTLSTTP---VDSNSPVTTSTEVSSSPTPAE 851

Query: 471  PVLISTAAPVDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIET-TPAPRTAETELTS 529
               + T+   +   P   T+ P++TT   +  T    TL T  ++T TP   + E   + 
Sbjct: 852  GTSMPTSTYSEGRTP--LTSMPVSTT---LVATSAISTLSTTPVDTSTPVTNSTEARSSP 906

Query: 530  TNFQDVSLPRVEDAMS----TSMSKETSSKTFSFLTSFSFTGTE-SVQTVIDAEATRTAL 584
            T  +  S+P           TSM   T+    S   + S T  + S       EAT +  
Sbjct: 907  TTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPT 966

Query: 585  TPEITL--ASTVAE--TMLSST-------ITGRVYTQNTPTADGHLLTLMSTRSASTSKA 633
            T E T    ST +E  T L+ST             T +T   D +     ST ++S    
Sbjct: 967  TAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPT 1026

Query: 634  PE--SGPTSTTDEAAHLFSSNETIWTSRPDQALLASMNTTTILTFVPNENFTSAFHENT- 690
             E  S PTST  E +    +   + T+    +  ++++TT   T  P   ++ A   +T 
Sbjct: 1027 AEGTSMPTSTPSEGSTPL-TRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTT 1085

Query: 691  ---------TYTEYLSATTNI---TPLKASPEGK--GTTANDATTARYTTAVSKLTSPWF 736
                     TY+E  +  T++   T L  S E     TT  D T+   TT+    +SP  
Sbjct: 1086 ADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVD-TSIPVTTSTEASSSPTT 1144

Query: 737  ANFSIV------SGTTSITNMPEFKLTTLL-------LKTIPMSTK-------PANELPL 776
            A  + +       GTT + +MP    TTL+       L T P+ +K        A+  P 
Sbjct: 1145 AEGTSIPTSPPSEGTTPLASMP--VSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPP 1202

Query: 777  TPRETVVP-------SVDIISTLACIQPNFSTEESASETTQTEINGAIVFGGTTTPVPKS 829
            T   T +P       S  + S      P  S+E S   T+  + +  +     T+  P +
Sbjct: 1203 TAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTT 1262

Query: 830  ATTQRLNATVTRKEATSHYLMRKSTIAAVAEVSP-FSTMLEVTDESAQRVTASVTVSSFP 888
            A    L  + T + +T   L+    ++     SP  ST+L    ++   V  S  VSS P
Sbjct: 1263 AEGTSLPTSTTSEGST---LLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSP 1319

Query: 889  DIEK-----LSTPLDNKTATTEVRESWLLT-----KLVKTTPRSSYNEMTEMFNFNHTYV 938
               +      ST  + +T  T +  +  L       ++ TTP  +   +T       +  
Sbjct: 1320 TPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTT------STE 1373

Query: 939  AHWTSETSEGISA--GSPTSGSTHIFGEPLGASTTRISETS-FSTTPTDRTATSLSDGIL 995
            A  +  TSEG S    +P+ G+T +   P+  +    SE S  S TP D +    +    
Sbjct: 1374 ACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEA 1433

Query: 996  PPQPTAAHSSATPVPVTHMFSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLS 1055
               PT A   + P         P+   S+    T V  SE STL+   +T V S+   ++
Sbjct: 1434 TSSPTTAEGISIPTSTPSEGKTPL--KSIPVSNTPVANSEASTLS---TTPVDSNSPVVT 1488

Query: 1056 STTMTTALVPPLDQTASTTIVIVPTHGDLIRTTSEATVISVRKTSMAVPSLTETPFHSLR 1115
            ST ++++   P     ++  +  P+ G    T+   +  +V   S  + SL+ TP  +  
Sbjct: 1489 STAVSSS---PTPAEGTSIAISTPSEGSTALTSIPVSTTTV--ASSEINSLSTTPAVT-- 1541

Query: 1116 LSTPVTAKAETTLFSTSVDTVTPSTHTLVCSKPPPDNIPPASSTHVISTTSTPEATQPIS 1175
             STPVT  ++ +   T+ D  +  T T      P  ++P ++   V S  +T   T   S
Sbjct: 1542 -STPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDS 1600

Query: 1176 QVEETSTYALSFPYTFSGGGVVASLATGTTE--TSVVDETTPSHISANKLTTSVNSHISS 1233
            + + T++   S   T  G  +  S  +  +   TS+   TTP  +++ + +T   + + S
Sbjct: 1601 KTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTP--VASPEASTLSTTPVDS 1658

Query: 1234 SATYRVHTPVSIQLVTSTSVLSSDKDQMTISLGKTPRTMEVTEMSPSKNSFISYSRGTPS 1293
            ++     T VS    + T    +     T + G+TP T      +P  +S IS    TP 
Sbjct: 1659 NSPVITSTEVS---SSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTP- 1714

Query: 1294 LEMTDTGFPETTKISSHQTHSPSE---IPLGTPSDGN--LASSPTSGSTQITPTLTSSNT 1348
                D   P TT   +  + + SE   +P  TPS+G   L S P S     TP L+S  +
Sbjct: 1715 ---VDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVS----TTPVLSSEAS 1767

Query: 1349 VGVHIPEMSTSLGKTALPSQALTITTFLCPEKESTSALPAYTPRTVEMIVNSTYVTHSVS 1408
                   +S +   T+ P    T  T      E TS +P  T       + ST V+H++ 
Sbjct: 1768 T------LSATPIDTSTPVTTSTEATSSPTTAEGTS-IPTSTLSEGMTPLTSTPVSHTLV 1820

Query: 1409 YGQDTSFVDTTTSSSTRISNPMDINTTFSHLHSLRTQPEVTSVASFISESTQTFPESLSL 1468
               + S + TT   S   ++P+  +T  S   S  T  E TS+A+       T   S+ +
Sbjct: 1821 ANSEASTLSTTPVDS---NSPVVTSTAVS---SSPTPAEGTSIATSTPSEGSTALTSIPV 1874

Query: 1469 STAGLYNDGFTVLSDR-------ITTAFSVPNVPTMLPRESSMATSTPIY---QMSSLPV 1518
            ST  + +     LS         +TT   V + PT     SSM TSTP      ++S+PV
Sbjct: 1875 STTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTAD-GSSMPTSTPREGRPPLTSIPV 1933

Query: 1519 NVTAFTSKKVSD-TPPIVITKSSKTMHPGCLKSPCTAT------------SGPMSEM--- 1562
            + T   S +++  +  +  T++  T +     SP TA             S P++ M   
Sbjct: 1934 STTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLS 1993

Query: 1563 SSIPVNNSAFTPATVSSDTSTRVGLFSTLLSSVTPRTTMTMQTSTLDVTPVIYAGATSKN 1622
            +++ V++ A T +T   DTST     +   SS T     ++QTST        AG     
Sbjct: 1994 TTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVST 2053

Query: 1623 KMVSSA----FTTEMIEAPSRITPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFS 1678
             +V S+     +T  +++ +++T +T  S +        T+        +   +  +  +
Sbjct: 2054 TLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLST-T 2112

Query: 1679 PLSSKSTGAISSIPKTTFSPFLSATQQSSQADEATTLGILSGITNRSLSTVNSGTGVALT 1738
            P++S     +S+ P  + SP +++T+ SS         I +  T+   ST +       +
Sbjct: 2113 PVASPEASTLSTTPVDSNSPVITSTEVSSSP-------IPTEGTSMQTSTYSDRRTPLTS 2165

Query: 1739 DTYSRITVPENMLSPTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTT--TNCFSSNTR 1796
               S   V  + +S      + TS     +P   S ++ S PT +  T+  T+  S  + 
Sbjct: 2166 MPVSTTVVASSAISTLSTTPVDTS-----TPVTNSTEARSSPTTSEGTSMPTSTPSEGST 2220

Query: 1797 KMTSLLEKTS--LTNYATSLN-TPV--SYPPWTPSSAT-LPSLTSFVYSPHSTEAEISTP 1850
              TS+   T   +T+ A++L+ TPV  S P  T + AT  P+       P ST +E +TP
Sbjct: 2221 PFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTP 2280

Query: 1851 KTSPPPTSQMV---EFPVLGTRMTSSNTQPLLMT--SWNIPTAEGSQFPISTT------- 1898
             TS P +  +V   E   L T    SNT     T  S   PTAEG+  P ST+       
Sbjct: 2281 LTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPL 2340

Query: 1899 INVPTSNEM----ETETLHLVPGPLST--FTASQTGLVSKDVMAMSSIPMSGILPNHGLS 1952
              +P S  M    ET TL   P   ST   T SQ G  S      +S+P S    + G +
Sbjct: 2341 TRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAG-SSPTTADDTSMPTSTY--SEGST 2397

Query: 1953 ENPSLSTSLRAITSTLADVKHTFEKMTTSVTPGTTLPSILSGATS--GSVISKSPIL--T 2008
               S+  S   + S+ A   H+   + TS TP TT     S  T+  G+ I  SP    T
Sbjct: 2398 PLTSVPVSTMPVVSSEAST-HSTTPVDTS-TPVTTSTEASSSPTTAEGTSIPTSPPSEGT 2455

Query: 2009 WLLSSLPSGSPPATVSNAPHV----------MTSSTVEVSK-----------------ST 2041
              L+S+P  + P   S A  +          MT+ST   S                  ST
Sbjct: 2456 TPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGST 2515

Query: 2042 FLTSDMISAHPF-----TNLTTLPSATMSTILTRT-IPTPTLGGITTGFPTSLPMSINVT 2095
             LTS  +S  P      + L+T P  + S ++T T I +       T  PTS     +  
Sbjct: 2516 LLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTP 2575

Query: 2096 DDIVYISTHPEASSR-TTITANPRTVSHPSSFSRKTMSPSTT--DHTLSVGAMPLPSSTI 2152
               + +ST P ASS  +T++  P   S P + S +T S  TT  D ++ +      S+++
Sbjct: 2576 LRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSL 2635

Query: 2153 TSSW-NRIPTASSPSTLIIPKPT-LDSLLNIMTTTSTVP----GASFPLISTGV-TYPFT 2205
            TS   + +P ASS ++ +   P    +L+   T TS+ P    G+S P  + G  + P T
Sbjct: 2636 TSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLT 2695

Query: 2206 -ATVSSPISSFFETTWLDSTPSFLSTEASTSPTATKSTVSFYNVEMSFSVFVEEPRIPIT 2264
               VS+ + +  E + L +TP   ST  +TS  A+ S  +     M  S    +   P+T
Sbjct: 2696 NILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRIST-PSDGSTPLT 2754

Query: 2265 SVI 2267
            S++
Sbjct: 2755 SIL 2757



 Score =  309 bits (792), Expect = 2e-83
 Identities = 545/2184 (24%), Positives = 883/2184 (40%), Gaps = 316/2184 (14%)

Query: 242  TVSQQIDMTTPSQITGVKPQNTAHSSTLL--------SQSIPIFATDYTTISYSNTTSP- 292
            T ++   M T +   G  P      ST+L        + +IP+ +  + T +   ++SP 
Sbjct: 376  TTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPT 435

Query: 293  ---------------------------PLETMTAQKILKTLVDE-----TATFAVDVLST 320
                                       P+ +  A  +  T VD      T+T A     T
Sbjct: 436  TAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPT 495

Query: 321  SSAISLPTQSISIDNT-TNSMKKTKSPSSESTKTTKMVEAMATEIFQPPTPSNFLSTSRF 379
            +   S+PT + S  +T   SM  +  P + S  +T     + T    P T S+  S+S  
Sbjct: 496  AEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTS--TPVTTSSEASSSST 553

Query: 380  T------------------KNSVVSTTSAIKSQSAVTKTT---------------SLFST 406
            T                   N  VST   + S+++ T TT               S  +T
Sbjct: 554  TPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTT 613

Query: 407  IESTSMSTTPCLKQKSTNTGALPISTAGQEFIESTAAGTVPWFTVEKTSPASTHV-GTAS 465
             E TSM T+    ++ T   ++ +ST     + S+ A T+    V+  +P +T    T+S
Sbjct: 614  AEGTSMPTS-TYSERGTTITSMSVSTT---LVASSEASTLSTTPVDSNTPVTTSTEATSS 669

Query: 466  SFPPEPVLISTAAPVDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETTPAPRTAET 525
            S   E   + T+   +   P   T+ P+ TT   +  +  + TL T  ++T+  P T  T
Sbjct: 670  STTAEGTSMPTSTYTEGSTP--LTSMPVNTT---LVASSEASTLSTTPVDTS-TPVTTST 723

Query: 526  ELTSTNFQDVSLPRVEDAMSTSMSKETSSKTFSFLTSFSFTGTESVQTVIDAEATRTALT 585
            E +S+       P   D    SM   T S+  + LTS   + T     +  +EA+  + T
Sbjct: 724  EASSS-------PTTAD--GASMPTSTPSEGSTPLTSMPVSKT----LLTSSEASTLSTT 770

Query: 586  P--EITLASTVAETMLSSTIT-GRVYTQNTPTADGHLLTLMSTRSASTSKAPESGPTSTT 642
            P    T  +T  E   S T T G     +TP+    LLT +   S +   +PE+   STT
Sbjct: 771  PLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPV-SITPVTSPEASTLSTT 829

Query: 643  DEAAHLFSSNETIWTSRPDQALLASMNTTTILTFVPNENFTSAFHENTTYTEYLSATTNI 702
               ++   +  T  +S P  A   SM T+   T+       ++   +TT    L AT+ I
Sbjct: 830  PVDSNSPVTTSTEVSSSPTPAEGTSMPTS---TYSEGRTPLTSMPVSTT----LVATSAI 882

Query: 703  TPLKASPEGKGTTANDATTARYTTAVSKLTSPWFANFSIVSGTTSITNMPEFKLTTLLLK 762
            + L  +P    T   ++T AR +   S+ TS      +   G+T +T+MP+         
Sbjct: 883  STLSTTPVDTSTPVTNSTEARSSPTTSEGTS--MPTSTPGEGSTPLTSMPD--------S 932

Query: 763  TIPMSTKPANELPLTPRETVVPSVDIISTLACIQPNFSTEESASETTQTEINGAIVFGGT 822
            T P+ +  A  L  TP +T  P     ST A   P  +T E  S  T T   G       
Sbjct: 933  TTPVVSSEARTLSATPVDTSTPVT--TSTEATSSP--TTAEGTSIPTSTPSEG------- 981

Query: 823  TTPVPKSATTQRLNATVTRKEATSHYLMRKSTIAAVAEVSPFSTMLEVTDESAQRVTASV 882
            TTP+  +  +  L   V   EA++       +   V   +P +T    T+ S+   TA  
Sbjct: 982  TTPLTSTPVSHTL---VANSEAST------LSTTPVDSNTPLTTS---TEASSPPPTAEG 1029

Query: 883  TVSSFPDIEKLSTPLDNKTATTEVRESWLLTKLVKTTPRSSYNEMTEMFNFNHTY-VAHW 941
            T        + STPL     +T +  S   T  + TTP  +   +T       TY  A  
Sbjct: 1030 TSMPTSTPSEGSTPLTRMPVSTTMVAS-SETSTLSTTPADTSTPVT-------TYSQASS 1081

Query: 942  TSETSEGISAGSPT--SGSTHIFGEPLGASTTRISETS-FSTTPTDRTATSLSDGILPPQ 998
            +S T++G S  + T   GST +   P+       SE S  STTP D +    +       
Sbjct: 1082 SSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSS 1141

Query: 999  PTAAHSSATPVP-----VTHMFSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSN 1053
            PT A  ++ P        T + S+PV+ + VV+ E     + P       +TS  ++ S+
Sbjct: 1142 PTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATS--TEASS 1199

Query: 1054 LSSTTMTTALVPPLDQTASTTIVIVPTHGDLIRTTSEATVISVRKTSMAVP-------SL 1106
               T   T++        ST +  +P     +  +SEA+ +S      + P       S 
Sbjct: 1200 PPPTAEVTSMPTSTPGERSTPLTSMPVRHTPV-ASSEASTLSTSPVDTSTPVTTSAETSS 1258

Query: 1107 TETPFHSLRLSTPVTAKAETTLFSTSVDT---VTPSTHTLVCSKPPPDNIPPASSTHVIS 1163
            + T      L T  T++  T L S  V T    +P   TL+ +  P D   P  +++ +S
Sbjct: 1259 SPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTT--PVDTKGPVVTSNEVS 1316

Query: 1164 TTSTPE--ATQPISQVEETSTYALSFPYTFSGGGVVASLATGTTETSVVDETTP---SHI 1218
            ++ TP    + P S   E  T   S P   +   +VAS A     T+ VD +TP   S  
Sbjct: 1317 SSPTPAEGTSMPTSTYSEGRTPLTSIPVNTT---LVASSAISILSTTPVDNSTPVTTSTE 1373

Query: 1219 SANKLTTSVNSHISSSATYRVHTPVSIQLVTSTSVLSSDKDQMTISLGKTPRTMEVTEMS 1278
            + +  TTS  + + +S      TP++   V++T V+SS+             T+  T + 
Sbjct: 1374 ACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEAS-----------TLSATPVD 1422

Query: 1279 PSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSPSE------------IPLGTPSDG 1326
             S       + GT S E T +  P T +  S  T +PSE             P+      
Sbjct: 1423 TS-------TPGTTSAEATSS--PTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEAS 1473

Query: 1327 NLASSPT-SGSTQITPTLTSSNTV---GVHIPEMSTSLGKTALPSQALTITTFLCPEKES 1382
             L+++P  S S  +T T  SS+     G  I   + S G TAL S  ++ TT    E  S
Sbjct: 1474 TLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINS 1533

Query: 1383 TSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINTTF---SHL 1439
             S  PA T   V      +  + S +    TS   +T S  +     + ++T     S  
Sbjct: 1534 LSTTPAVTSTPV---TTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEA 1590

Query: 1440 HSLRTQP--EVTSVASFISESTQTFPESLSLSTAGLYNDGFTVLSDRITTAFSVPNVPTM 1497
            ++L T P    T V +    S+ T  E  S+ T    ++G  +L     T+  V   P  
Sbjct: 1591 NTLSTTPIDSKTQVTASTEASSSTTAEGSSM-TISTPSEGSPLL-----TSIPVSTTPVA 1644

Query: 1498 LPRESSMATSTPIYQMSSLPVNVTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTA--- 1554
             P  S+++T TP+        N    TS +VS +P      S  T      ++P T+   
Sbjct: 1645 SPEASTLST-TPV------DSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITV 1697

Query: 1555 -----TSGPMSEMSSIPVNNSAFTPATVSSDT-STRVGLFSTLLSSVTPRTTMTMQTS-T 1607
                  S  +S +S+ PV+NS  TP T S++  S+      T + + TP    T  TS  
Sbjct: 1698 RTTPVASSAISTLSTTPVDNS--TPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIP 1755

Query: 1608 LDVTPVIYAGATSKNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTLPFVKTVPTTIMAGI 1667
            +  TPV+ + A        S  +   I+  + +T +T  + + PT     ++PT+ ++  
Sbjct: 1756 VSTTPVLSSEA--------STLSATPIDTSTPVTTST-EATSSPTTAEGTSIPTSTLSEG 1806

Query: 1668 VTPFVGTTAFSPLSSKS-TGAISSIPKTTFSPFLSATQQSSQADEATTLGILSGITNRSL 1726
            +TP   T     L + S    +S+ P  + SP +++T  SS    A    I +   +   
Sbjct: 1807 MTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEG- 1865

Query: 1727 STVNSGTGVALTDTYSRITVPENMLSPTHA-DSLHTSFNIQVSPSLTSFKSASGPTKNVK 1785
            ST  +   V+ T   S  T   N LS T A  S   +   QVS S T+   +S PT   +
Sbjct: 1866 STALTSIPVSTTTVASSET---NTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPR 1922

Query: 1786 TTTNCFSSNTRKMTSLL--EKTSLTNYATSLNTPVSYPPWTPSSATLPSLTSFVYSPHST 1843
                  +S     T++   E  +L+       TPV+      SS T    TS    P   
Sbjct: 1923 EGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSM---PTPA 1979

Query: 1844 EAEISTPKTSPPPTSQMVEFPVLGTRMTSSNTQPLLMTSWNIPTAEGSQFPIS---TTIN 1900
             +E STP TS P ++ +    V+ +  ++ +T P+  ++    + EGS  P +   T+I 
Sbjct: 1980 YSEGSTPLTSMPLSTTL----VVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQ 2035

Query: 1901 VPTSNEMETETLHLVPGPLSTFTASQTGLVSKDVMAMSSIPMSGILPNHGLSENPSLSTS 1960
              T +E  T        PL+    S T +VS +   +S+ P+         +E  S +T+
Sbjct: 2036 TSTPSERTT--------PLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATA 2087

Query: 1961 LRAITSTLADVKHTFEKMTTSVTPGTTLPSILSGATSGS--VISKSPILTWLLSSLPSGS 2018
              +  +  A  + +   + TS+   TT  +    +T  +  V S SP++T   S+  S S
Sbjct: 2088 EGSSMTISAPSEGS--PLLTSIPLSTTPVASPEASTLSTTPVDSNSPVIT---STEVSSS 2142

Query: 2019 PPATVSNAPHVMTSSTVEVSKSTF-LTSDMISAHPFTNLTTLPSATMSTIL----TRTIP 2073
            P  T   +    T S      ++  +++ ++++   + L+T P  T + +      R+ P
Sbjct: 2143 PIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSP 2202

Query: 2074 TPTLGGITTGFPTSLPMSINVTDDIVYISTHPEASSR-TTITANPRTVSHPSSFSRK-TM 2131
            T + G   T  PTS P   +     + +ST P  +S  +T++A P   S P + S + T 
Sbjct: 2203 TTSEG---TSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATS 2259

Query: 2132 SPSTTD------HTLSVGAMPLPSSTITSSWNRIPTASSPSTLIIPKPT-LDSLLNIMTT 2184
            SP+T +       TLS G  PL S  ++ +       S+ ST  +   T   +     + 
Sbjct: 2260 SPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSP 2319

Query: 2185 TSTVPGASFP--LISTGVTYPFTATVSSPISSFFETTWLDSTPSFLSTEASTSPTATKST 2242
              T  G S P    S G T      VS+ + + FET+ L +TP+  ST  +T   A  S 
Sbjct: 2320 PPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSP 2379

Query: 2243 VSFYNVEMSFSVFVEEPRIPITSV 2266
             +  +  M  S +  E   P+TSV
Sbjct: 2380 TTADDTSMPTSTY-SEGSTPLTSV 2402



 Score =  292 bits (748), Expect = 3e-78
 Identities = 510/2083 (24%), Positives = 844/2083 (40%), Gaps = 262/2083 (12%)

Query: 305  TLVDETATFAVD---VLSTSSAISLPTQSISIDNTTNSMKKTKSPSSESTKTTKMVEAMA 361
            T    T+T  V+    LS S+   + +   S+ + T  +  T+   +ES +TT    + +
Sbjct: 67   TATGTTSTNVVEPRMYLSCSTNPEMTSIESSVTSDTPGVSSTRMTPTES-RTTSESTSDS 125

Query: 362  TEIFQPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFSTIESTSMSTTPCLKQK 421
            T +F    PS+   TS  T         +  S+ +++      ST+   S +  P  +  
Sbjct: 126  TTLF----PSSTEDTSSPTTPEGTDVPMSTPSEESIS------STMAFVSTAPLPSFEAY 175

Query: 422  STNTGALPISTAGQEFIESTAAGTVPWFTVEKTSPASTHVGTASSFPPEPVLISTAAPVD 481
            ++ T  + +ST       ST A + P      T P ST+  +  S P       T+ P  
Sbjct: 176  TSLTYKVDMST---PLTTSTQASSSPTTPESTTIPKSTN--SEGSTP------LTSMPAS 224

Query: 482  SVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETTPAPRTAE-TELTSTNFQDVSLPRV 540
            ++   +  A  L TT ++I+  V      T   + + +P TAE   L+++     S P  
Sbjct: 225  TMKVASSEAITLLTTPVEISTPV------TISAQASSSPTTAEGPSLSNSAPSGGSTPLT 278

Query: 541  EDAMSTSMSKETSSKTFSFLTSFSFTGTESVQTVIDAEATRTALTPEITLASTVAETMLS 600
               +S  +   + + T S     +     ++  +   EA+ +  T E T   T   T  S
Sbjct: 279  RMPLSVMLVVSSEASTLS-----TTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGS 333

Query: 601  STITGRVYTQNTPTADGHLLTLMST-----RSASTSKAPESGPTS--TTDEAAHLFSSNE 653
            + +T        P A   + TL  T        +TS  P S PT+   T       S   
Sbjct: 334  TPLTS-TPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGS 392

Query: 654  TIWTSRPDQALLASMNTTTILTFVPNENFT-----SAFHENTTYTEYLSATTNI------ 702
            T  T+ P   +L + +  +  + +P ++ T     S    + T  E  S  T+       
Sbjct: 393  TPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGST 452

Query: 703  ----TPLKASPEGKGTTANDATT-----ARYTTAVSKLTSPWFANFSIVSGTTSITNMPE 753
                 P+  +P      +N +TT      + TT+    +SP  A   + S  TS  +   
Sbjct: 453  PLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTA--EVNSMPTSTPSEGS 510

Query: 754  FKLTTLLLKTIPMSTKPANELPLTPRETVVPSVDIISTLACIQPNFSTEESASETTQTEI 813
              LT++ + T+P+++  A+ L  TP +T  P    ++T        S+E S+S TT    
Sbjct: 511  TPLTSMSVSTMPVASSEASTLSTTPVDTSTP----VTT--------SSEASSSSTTPE-- 556

Query: 814  NGAIVFGGTTTP--VPKSATTQRLNATVTRKEATSHYLMRKSTIAAVAEVSPFSTMLEVT 871
                   GT+ P   P   +T   N  V+ +   S      ST  A +     +T  E +
Sbjct: 557  -------GTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTF-VTTSSEAS 608

Query: 872  DESAQRVTASVTVSSFPDIEKLSTPLDNKTATTEVRESWLLTKLVKTTPRSSYNEMTEMF 931
              S      S+  S++   E+ +T      +TT V  S   T  + TTP  S   +T   
Sbjct: 609  SSSTTAEGTSMPTSTYS--ERGTTITSMSVSTTLVASSEAST--LSTTPVDSNTPVTT-- 662

Query: 932  NFNHTYVAHWTSETSEGIS--AGSPTSGSTHIFGEPLGASTTRISETS-FSTTPTDRTAT 988
                +  A  +S T+EG S    + T GST +   P+  +    SE S  STTP D +  
Sbjct: 663  ----STEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTP 718

Query: 989  SLSDGILPPQPTAAHSSATPVPVTHMFSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVL 1048
              +       PT A  ++ P       S P+  +S+   +T +T SE STL    ST+ L
Sbjct: 719  VTTSTEASSSPTTADGASMPTSTPSEGSTPL--TSMPVSKTLLTSSEASTL----STTPL 772

Query: 1049 SDVSNLSSTTMTTALVPPLDQTASTTIVIVPTHGDLIRTTSEATVISVRKTSMAVPSLTE 1108
               +++  TT T A   P     ++  +  P+ G  + T+   ++  V  TS    +L+ 
Sbjct: 773  DTSTHI--TTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPV--TSPEASTLST 828

Query: 1109 TPFHSLRLSTPVTAKAETTLFSTSVDTVTPSTHTLVCSKPPPDNIPPAS---STHVISTT 1165
            TP  S   ++PVT   E +   T  +  +  T T    + P  ++P ++   +T  IST 
Sbjct: 829  TPVDS---NSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTL 885

Query: 1166 STP--EATQPISQVEETSTYALSFPYTFSGGGVVASL-ATGTTE-TSVVDETTPSHISAN 1221
            ST   + + P++     ST A S P T  G  +  S    G+T  TS+ D TTP   S  
Sbjct: 886  STTPVDTSTPVT----NSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEA 941

Query: 1222 KLTTSVNSHISSSATYRVHTPVSIQLVTSTSVLSSDKDQMTISLGKTPRTME-VTEMSPS 1280
            +  ++     S+  T       S      TS+ +S   + T  L  TP +   V     S
Sbjct: 942  RTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEAS 1001

Query: 1281 KNSFISYSRGTPSLEMTDTGF-PETTKISSHQTHSPSE-------IPLGT-----PSDGN 1327
              S       TP    T+    P T + +S  T +PSE       +P+ T          
Sbjct: 1002 TLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETST 1061

Query: 1328 LASSPTSGSTQIT----PTLTSSNTVGVHIPEMSTSLGKTALPSQALTITTFLCPEKEST 1383
            L+++P   ST +T     + +S+   G  +P  + S G T L S  ++    +  E  + 
Sbjct: 1062 LSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTL 1121

Query: 1384 SALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINTTF---SHLH 1440
            S  P  T   V     ST  + S +  + TS   +  S  T     M ++TT    S  +
Sbjct: 1122 STTPVDTSIPV---TTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEAN 1178

Query: 1441 SLRTQPEVTSVASFISESTQTFP-----ESLSLSTAGLYNDGFTVLSDRIT-------TA 1488
            +L T P  +      S    + P      S+  ST G  +   T +  R T       + 
Sbjct: 1179 TLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEAST 1238

Query: 1489 FSVPNVPTMLPRESSMATST--PIYQMSSLPVNVTAFTSKKVSDTPPIVITKSSKTMHPG 1546
             S   V T  P  +S  TS+     + +SLP + T+  S  ++  P  V T    +    
Sbjct: 1239 LSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIP--VSTTLVTSPEAS 1296

Query: 1547 CLKSPCTATSGPM---SEMSSIPVNNSAFTPATVSSDTSTRVGLFSTLLSSVTPRTTMTM 1603
             L +    T GP+   +E+SS P      TPA  +S  ++      T L+S+   TT+  
Sbjct: 1297 TLLTTPVDTKGPVVTSNEVSSSP------TPAEGTSMPTSTYSEGRTPLTSIPVNTTLVA 1350

Query: 1604 QT--STLDVTPVIYA-GATSKNKMVSSAFTTEMIEAPSR-----ITPTTFLSPTEPTLPF 1655
             +  S L  TPV  +   T+  +  SS  T+E    P+       TP T +  +  T P 
Sbjct: 1351 SSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVS--TTPV 1408

Query: 1656 VKTVPTTIMAGIV-TPFVGTTAFSPLSSKSTGAISSIPKTTFS---------PFLSATQQ 1705
            V +  +T+ A  V T   GTT+    SS +T    SIP +T S         P  +    
Sbjct: 1409 VSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVA 1468

Query: 1706 SSQADEATTLGILSG---ITNRSLS---TVNSGTGVAL------TDTYSRITVPENMLSP 1753
            +S+A   +T  + S    +T+ ++S   T   GT +A+      +   + I V    ++ 
Sbjct: 1469 NSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVAS 1528

Query: 1754 THADSLHTSFNIQVSPSLTSFKSASGPTKNVKTT--TNCFSSNTRKMTSLLEKTSLTNYA 1811
            +  +SL T+  +  +P  T  +++S PT    T+  T+ +S  +  +TSL   T L   +
Sbjct: 1529 SEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLV-VS 1587

Query: 1812 TSLNTPVSYPPWTPSSATLPSLTSFVYSPHSTEAEISTP-KTSPPPTSQMVE-FPVLGTR 1869
            +  NT  + P  + +  T  +  S   +   +   ISTP + SP  TS  V   PV    
Sbjct: 1588 SEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPE 1647

Query: 1870 MTSSNTQPLLMTSWNIPTAEGSQFPI-STTINVPTSNEMETETLHLVPGPLSTFTASQTG 1928
             ++ +T P+   S  I + E S  P  +   ++PTS   E  T      PL++ T   T 
Sbjct: 1648 ASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRT------PLTSITVRTTP 1701

Query: 1929 LVSKDVMAMSSIPMSGILPNHGLSENPSLSTSLRAITSTLADVKHTFEKMTTSVTPGTTL 1988
            + S  +  +S+ P+    P        + ST  R+  +T           +   TP T++
Sbjct: 1702 VASSAISTLSTTPVDNSTP-------VTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSI 1754

Query: 1989 PSILSGATS--GSVISKSPI--LTWLLSSLPSGSPPATV--SNAPHVMTSSTVEVSKSTF 2042
            P   +   S   S +S +PI   T + +S  + S P T   ++ P    S  +    ST 
Sbjct: 1755 PVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTP 1814

Query: 2043 LTSDMISAHPFTNLTTLPSATMSTILTRTI----PTPTLGGITTGFPTSLPMSINVTDDI 2098
            ++  +++    + L+T P  + S ++T T     PTP  G   T   TS P   +     
Sbjct: 1815 VSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEG---TSIATSTPSEGSTALTS 1871

Query: 2099 VYISTHPEASSRT-TITANPRTVSHP-SSFSRKTMSPSTTDHTLSVGAMP---------L 2147
            + +ST   ASS T T++  P   S P +++++ + SP+T D +    + P         +
Sbjct: 1872 IPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSI 1931

Query: 2148 PSSTITSSWNRIPTASSPSTLIIPKPTLDSLLNIMTTTSTVPGASFPLIS--------TG 2199
            P ST T + + I T S  +TL   +  + +     ++ +T  G S P  +        T 
Sbjct: 1932 PVSTTTVASSEINTLS--TTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTS 1989

Query: 2200 VTYPFTATVSSPISSFFETTWLDSTPSFLSTEASTSPTATKST 2242
            +    T  VSS  S+   T    STP+  STE S+SPT    T
Sbjct: 1990 MPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGT 2032



 Score =  278 bits (712), Expect = 5e-74
 Identities = 514/2046 (25%), Positives = 837/2046 (40%), Gaps = 303/2046 (14%)

Query: 238  EKSTTVSQQIDMTTP--SQITGVKPQNTAHSSTLLSQSIPIFATDYTTISYSNT--TSPP 293
            E ST  +  +D +TP  +         TA  +++ + ++    T  T+I  S+T   +  
Sbjct: 2236 EASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSE 2295

Query: 294  LETMTAQKILKTLVDETATFAVDVLSTSSAISLPTQSISIDNT----------------T 337
            + T++   +       T+T A     T+   S+PT + S  NT                T
Sbjct: 2296 VSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFET 2355

Query: 338  NSMKKTKSPSSESTKTTKMVEAMATEIFQPPTPSNFLSTSRFTKNSV-VSTTSAIKSQSA 396
            +++  T + +S    T     +  T       P++  S       SV VST   + S+++
Sbjct: 2356 STLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEAS 2415

Query: 397  VTKTT---------------SLFSTIESTSMSTTPCLKQKSTNTGALPISTAGQEFIEST 441
               TT               S  +T E TS+ T+P   + +T   ++P+ST     + S+
Sbjct: 2416 THSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPP-SEGTTPLASMPVSTTP---VVSS 2471

Query: 442  AAGTVPWFTVEKTSPASTHVGTASSFPPEP----VLISTAAPVDSVFPRNQTAFPLATTD 497
             AGT+    V+ ++P +T    ASS P       V ISTA+   ++     T+ P++TT 
Sbjct: 2472 EAGTLSTTPVDTSTPMTTST-EASSSPTTAEDIVVPISTASEGSTLL----TSIPVSTTP 2526

Query: 498  MKIAFTVHSLTLPTRLIETTPAPRTAETELTSTNFQDVSLPRVEDAMSTSMSKETSSKTF 557
            +    +  + TL T  +++  +P    TE++S+            A  TSM   T S+  
Sbjct: 2527 VA---SPEASTLSTTPVDSN-SPVVTSTEISSS---------ATSAEGTSMPTSTYSEGS 2573

Query: 558  SFLTSFSFTGTESVQTVIDAEATRTALTPEITLASTVAETMLSSTITGRVYTQ---NTPT 614
            + L S       S + +  +EA+  + TP  T       T  SS+ T    T    +TP+
Sbjct: 2574 TPLRSMPV----STKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPS 2629

Query: 615  ADGHLLT--LMSTRSASTSKAPESGPTSTTDEAAHLFSSNETIWTSRPDQALLASMNTTT 672
                 LT  L+ST   ++S   E+   STT        +  T  +S P  A  +SM T+T
Sbjct: 2630 EVSTSLTSILVSTMPVASS---EASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTST 2686

Query: 673  ILTFVPNENFTSAFHENTTYTEYLSATTNITPLKASPEGKGTTANDATTARYTTAVSKLT 732
                 P E        +T  T  L +TT +   +AS     TT  D +T   T+A +  +
Sbjct: 2687 -----PGER-------STPLTNILVSTTLLANSEAST--LSTTPVDTSTPVTTSAEASSS 2732

Query: 733  SPWFANFSIVSGTTSITNMPEFKLTTLLLKTIPMSTKPANELPLTPRETVVPSVDIISTL 792
                   S+   T S  + P   LT++L+ T+P+++  A+ +  T  +T +P    ++T 
Sbjct: 2733 PTTAEGTSMRISTPSDGSTP---LTSILVSTLPVASSEASTVSTTAVDTSIP----VTT- 2784

Query: 793  ACIQPNFSTEESASETTQTEINGAIVFGGTTTPVPKSATTQRLNATVTRKEATSHYLMRK 852
                   STE S+S TT              T +P S  ++   +T       +H     
Sbjct: 2785 -------STEASSSPTT-----------AEVTSMPTSTPSE--TSTPLTSMPVNH----- 2819

Query: 853  STIAAVAEVSPFSTMLEVTDESAQRVTASVTVSSFPDI-EKLSTPLDNKTATTEVRESWL 911
             T  A +E    ST      +++  VT S   SS P   E +  P+     +T    S L
Sbjct: 2820 -TPVASSEAGTLST---TPVDTSTPVTTSTKASSSPTTAEGIVVPI-----STASEGSTL 2870

Query: 912  LTKL-VKTTPRSSYNEMTEMFNFNHTYVAHWTSETSEGISAGSPTSGSTHIFGEPLGAST 970
            LT + V TTP +S    T       T +   TS  +EG S+ +   G++     P   ST
Sbjct: 2871 LTSIPVSTTPVASSEASTLSTTPVDTSIPVTTS--TEGSSSPTTAEGTSMPISTPSEVST 2928

Query: 971  TRIS------------ETSFSTTPTDRTATSLSDGILPPQPTAAHSSATPVPVTHMFSLP 1018
               S             ++ STTP D      +       PT A  ++ P+        P
Sbjct: 2929 PLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTP 2988

Query: 1019 VNGSSVVAEETEVTMSEPSTLARA-FSTSVLSDVSNLSSTTMTTA-------------LV 1064
            +   SV      V  SE STL+R    TS     S  +S++ TTA               
Sbjct: 2989 LTSMSV--STMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGST 3046

Query: 1065 PPLDQTASTTIVIVPTHGDLIRTT--SEATVISVRK----------TSMAVPSLTE--TP 1110
            P      STT V +P    L  T   S + V++  +          TSM + + +E  TP
Sbjct: 3047 PLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTP 3106

Query: 1111 FHSLRLST-PVTAKAETTLFSTSVDTVTPSTHTLVCSKPPPDNIPPASSTHVISTTSTPE 1169
               + +ST PVT+ A +TL +T VDT TP T +      P  +   +  T   S  STP 
Sbjct: 3107 LTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPL 3166

Query: 1170 ATQPISQVEETSTYALSFPYTFSGGGVVASLATGTTETSVVDETTP--SHISANKLTTSV 1227
               P+S +                  +V S    T   + VD +TP  +   A   TT+ 
Sbjct: 3167 TYMPVSTM------------------LVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAE 3208

Query: 1228 NSHISSSATYRVHTPVSIQLVTSTSVLSSDKDQMTISL--GKTPRTMEV-TEMSPSKNSF 1284
             + I +S      TP++   V++T V SS+   ++ +     TP T       SP     
Sbjct: 3209 GTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEG 3268

Query: 1285 ISYSRGTPSLEMTD-TGFP-ETTKISSHQTHSPSEIPLGTPSDGNLASSPTSGSTQITPT 1342
             S    TPS   T  T  P  TT ++S +T + S  P  T       S+P +  +Q + +
Sbjct: 3269 TSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADT-------STPVTTYSQASSS 3321

Query: 1343 LTSSNTVGVHIPEMSTSLGKTALPSQALTITTFLCPEKESTSALPAYTPRTVEMIVNSTY 1402
               ++  G  +P  + S G T L + + + T  +  E  + S  P  T   V     ST 
Sbjct: 3322 PPIAD--GTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPV---TTSTE 3376

Query: 1403 VTHSVSYGQDTSFVDTTTSSSTRISNPMDINTT---FSHLHSLRTQP---EVTSVASFIS 1456
             + S +  + TS   ++ S  T     M ++TT    S +++L T P         S  +
Sbjct: 3377 ASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEA 3436

Query: 1457 ESTQTFPESLSLSTAGLYNDGFTVLSDRITTAFSVPNVPTMLPRESSMATSTPIYQMSSL 1516
             S+ T  E  SL T+   ++G T LS              ++P  ++   S+    +S+ 
Sbjct: 3437 SSSPTIAEGTSLPTS-TTSEGSTPLS--------------IMPLSTTPVASSEASTLSTT 3481

Query: 1517 PVNVTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTATSG--PMSEM--SSIPVNNS-A 1571
            PV+    TS  V+ + P   T SS T          TA  G  P++ M  S+ PV +S A
Sbjct: 3482 PVD----TSTPVTTSSP---TNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEA 3534

Query: 1572 FTPATVSSDTSTRVGLFSTLLSSVTPRTTMTMQTST-LDVTPVIYAGATSKNKMVSSAFT 1630
             T +T   D++T V   S   SS       TM+ ST  + +  +     S   + SS  +
Sbjct: 3535 STLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEAS 3594

Query: 1631 TEMIEAPSRITP--TTFLSPTEPTLPFVKTVPTTIMAGIVTPF-VGTTAFSPLSSKSTGA 1687
            T    +  R TP  T+  S + PT P V T+P +  + + TP  +   + + ++    G 
Sbjct: 3595 TPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGT 3654

Query: 1688 ISSIPKTTFSPFLSATQQSSQ--ADEATTLGI------LSGITNRSLST--VNSGTGVAL 1737
             S++P  T +P +++TQ SS     E TT+ I       + +T   +ST  V S  G  L
Sbjct: 3655 ASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTL 3714

Query: 1738 TDTYSRITVPENMLSPTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTT--TNCFSSNT 1795
            + T S +T      S     S  T  +  +S S+    S  G T  V TT  T    S+T
Sbjct: 3715 S-TPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESST 3773

Query: 1796 RKMTSLLEKTSLTNYATSLNTPVSYP-----PWTPSSATLPSLTSFVYSPHS--TEAEIS 1848
              + S+    S+T  +   ++P +       P + +S     LT+ + SP S  + +E S
Sbjct: 3774 PSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEAS 3833

Query: 1849 TPKTSPPPTSQMVEFPVLGTRMTSSNTQPLLMTSWNIPTAEGSQFPISTTI---NVPTSN 1905
            T  T P  TS     P+L +    S + P  +T+  I        P++T +    +PTS 
Sbjct: 3834 TLSTPPGDTST----PLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTS- 3888

Query: 1906 EMETETLHLVPGPLSTFTASQTGLVSKDVMAMSSIPMSGILPNHGLSENPSLSTSL---- 1961
                 ++   P PL T   S T   S D  +  +IP++  +    ++E  +  T++    
Sbjct: 3889 -FPGASIASTP-PLDT---STTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPS 3943

Query: 1962 RAITSTLADV-KHTFEKMTTSVTPGTTL--PSILSGATSGSVISKSPILTWLLSSLPSGS 2018
              +TS+ ADV   T   ++T V   T L  PS  S +T+ S  +     T    ++ + +
Sbjct: 3944 TPVTSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTT---PAMTTAA 4000

Query: 2019 P--PATVSNAPHVMTSSTVEVSKSTFLTSDMISAHPFTNLTTLP------SATMSTILTR 2070
            P    T+S AP    +++   + S    S   + H  T++TT P      S+  STI + 
Sbjct: 4001 PLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESSRPSTITSH 4060

Query: 2071 TIPTPTLGGITTGFPTSLPMSINVTDD-IVYISTHPEASSRTTITANPRTVSHPSSFSRK 2129
            TIP       ++  PT+   S  V  + +  ++T  + S+RTT      T + P++ + K
Sbjct: 4061 TIPPTFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNTTIK 4120

Query: 2130 TMSPST 2135
            +   ST
Sbjct: 4121 SNPTST 4126



 Score =  221 bits (562), Expect = 1e-56
 Identities = 384/1533 (25%), Positives = 609/1533 (39%), Gaps = 261/1533 (17%)

Query: 942  TSETSEGISAGSPTSGSTHIFGEPLGASTTRI----SETSFSTTP--TDRTATSLSDGIL 995
            TS+T  G+S+   T   +    E    STT       +TS  TTP  TD   ++ S+  +
Sbjct: 99   TSDTP-GVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESI 157

Query: 996  PPQPTAAHSSATPVPVTHMFS---LPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVS 1052
                T A  S  P+P    ++     V+ S+ +   T+ + S P+T     ST++    +
Sbjct: 158  --SSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQAS-SSPTTPE---STTIPKSTN 211

Query: 1053 NLSSTTMTTALVPPLDQTASTTIVIVPTHGDLIRTTSEATVISVRKTSMAVPSLTETPFH 1112
            +  ST +T+     +   +S  I ++ T  ++      +T +++   + + P+  E P  
Sbjct: 212  SEGSTPLTSMPASTMKVASSEAITLLTTPVEI------STPVTISAQASSSPTTAEGP-- 263

Query: 1113 SLRLSTPVTAKAETTLFSTSVDTVTPSTHTLVCSKPPPDNIPPASSTHVISTTSTPEATQ 1172
            SL  S P       T    SV  V  S  + + + P   NIP  +ST   S+ +T E T 
Sbjct: 264  SLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTS 323

Query: 1173 -PISQVEE-----TSTYALSFPYTFSGGGVVASLATGTTETSVVDETTPSHI-SANKLTT 1225
             P S   E     TST A + P   S    + S+    T T V   T PS + +  + T+
Sbjct: 324  IPTSTYTEGSTPLTSTPASTMPVATSEMSTL-SITPVDTSTLVTTSTEPSSLPTTAEATS 382

Query: 1226 SVNSHISSSATYRVHTPVSIQLVTS-----TSVLSSDKDQM------------------- 1261
             + S +S  +T   + PVS  LV S     TS +  D                       
Sbjct: 383  MLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSI 442

Query: 1262 ---TISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTD-------TGFPETTKISSHQ 1311
               T S G TP T      +P  +S  S    TP    T        +  P T +++S  
Sbjct: 443  ATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMP 502

Query: 1312 THSPSE------------IPLGTPSDGNLASSPTSGSTQITPT--LTSSNTV--GVHIPE 1355
            T +PSE            +P+ +     L+++P   ST +T +   +SS+T   G  IP 
Sbjct: 503  TSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPT 562

Query: 1356 MSTSLGKTALPSQALTITTFLCPEKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSF 1415
             + S G T L +  ++    +  E  +TS  PA    +   +  S+  + S +  + TS 
Sbjct: 563  STPSEGSTPLTNMPVSTRLVVSSEASTTSTTPA---DSNTFVTTSSEASSSSTTAEGTSM 619

Query: 1416 VDTTTSSSTRISNPMDINTTF---SHLHSLRTQP-----EVTSVASFISESTQTFPESLS 1467
              +T S        M ++TT    S   +L T P      VT+     S ST     S+ 
Sbjct: 620  PTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMP 679

Query: 1468 LSTAGLYNDGFTVL-------------------------SDRITTAFSVPNVPTMLPRES 1502
             ST   Y +G T L                         S  +TT+    + PT     +
Sbjct: 680  TST---YTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTAD-GA 735

Query: 1503 SMATSTP---IYQMSSLPVNVTAFTSKK---VSDTPPIVITKSSKTMHPGCLKSPCTATS 1556
            SM TSTP      ++S+PV+ T  TS +   +S TP    T  + +    C  +    TS
Sbjct: 736  SMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTS 795

Query: 1557 GPMSE-------MSSIPV-------------------NNSAFTPAT-VSSDTSTRVGL-- 1587
             P+S        ++SIPV                   +NS  T +T VSS  +   G   
Sbjct: 796  MPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSM 855

Query: 1588 -FSTLLSSVTPRTTMTMQT--------STLDVTPV-IYAGATSKNKMVSSAFTTEMIEAP 1637
              ST     TP T+M + T        STL  TPV      T+  +  SS  T+E    P
Sbjct: 856  PTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMP 915

Query: 1638 SRITP----TTFLSPTEPTLPFVKTVPTTIMAGIV---TPFVGTT--AFSPLSSKSTGAI 1688
            +  TP    T   S  + T P V +   T+ A  V   TP   +T    SP +++ T   
Sbjct: 916  TS-TPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIP 974

Query: 1689 SSIPKTTFSPFLSATQQSSQA--DEATTLGILSGITNRSLSTVNSGT-------GVAL-T 1738
            +S P    +P  S     +     EA+TL      +N  L+T    +       G ++ T
Sbjct: 975  TSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPT 1034

Query: 1739 DTYS-------RITVPENMLSPTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTT---T 1788
             T S       R+ V   M++ +   +L T+     S  +T++  AS  +     T   T
Sbjct: 1035 STPSEGSTPLTRMPVSTTMVASSETSTLSTT-PADTSTPVTTYSQASSSSTTADGTSMPT 1093

Query: 1789 NCFSSNTRKMTSLLEKTSL--TNYATSLNTPVSYPPWTPSSATLPSLTSFVYSPHSTEAE 1846
            + +S  +  +TS+   T L  ++ A++L+T       TP   ++P  TS   S   T AE
Sbjct: 1094 STYSEGSTPLTSVPVSTRLVVSSEASTLST-------TPVDTSIPVTTSTEASSSPTTAE 1146

Query: 1847 ISTPKTSPPP--TSQMVEFPVLGTRMTSSNTQPLLMTSWNIPTAEGSQFPISTTINVPTS 1904
             ++  TSPP   T+ +   PV  T + SS    L  T    P    +Q   ST  + P  
Sbjct: 1147 GTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTT----PVDSKTQVATSTEASSPPP 1202

Query: 1905 NEMETETLHLVPG----PLSTFTASQTGLVSKDVMAMSSIPMSGILPNHGLSENPSLSTS 1960
                T      PG    PL++     T + S +   +S+ P+    P    +E  S  T+
Sbjct: 1203 TAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTT 1262

Query: 1961 LRAITSTLADVKHTFEKMTTSVTPGTTLPSILSGAT--SGSVISKSPILTWLLSSLPSGS 2018
                TS           + TS+   TTL +    +T  +  V +K P++T   S+  S S
Sbjct: 1263 AEG-TSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVT---SNEVSSS 1318

Query: 2019 P-PATVSNAPHVMTSSTVEVSKSTFLTSDMISAHPFTNLTTLP--SATMSTILTRTIPTP 2075
            P PA  ++ P    S       S  + + ++++   + L+T P  ++T  T  T    +P
Sbjct: 1319 PTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSP 1378

Query: 2076 TLGGITTGFPTSLPMSINVTDDIVYISTHPEASSR-TTITANPRTVSHPSSFSRKTMSPS 2134
            T     T  P S P         + +ST P  SS  +T++A P   S P + S +  S  
Sbjct: 1379 TTSE-GTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSP 1437

Query: 2135 TTDHTLSV-------GAMPLPSSTITSSWNRIPTASSPSTLIIPKPTLDSLLNIMTTTST 2187
            TT   +S+       G  PL S  ++++    P A+S ++ +   P +DS   ++T+T+ 
Sbjct: 1438 TTAEGISIPTSTPSEGKTPLKSIPVSNT----PVANSEASTLSTTP-VDSNSPVVTSTAV 1492

Query: 2188 ------VPGASFPLIS--------TGVTYPFTATVSSPISSFFETTWLDSTPSFLSTEAS 2233
                    G S  + +        T +    T   SS I+S   T  + STP    ++AS
Sbjct: 1493 SSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQAS 1552

Query: 2234 TSPTATKSTVSFYNVEMSFSVFVEEPRIPITSV 2266
            +SPT    T       M  S +  E   P+TS+
Sbjct: 1553 SSPTTADGT------SMQTSTY-SEGSTPLTSL 1578



 Score =  172 bits (436), Expect = 5e-42
 Identities = 306/1195 (25%), Positives = 479/1195 (40%), Gaps = 208/1195 (17%)

Query: 1195 GVVASLATGTTETSVVDETTPSHISANKLTTSVNSHISSSATYRVHTPVSIQLVTSTSVL 1254
            G  A+ ATGTT T+VV+       S N   TS+ S ++S       T ++     +TS  
Sbjct: 62   GSAANTATGTTSTNVVEPRMYLSCSTNPEMTSIESSVTSDTPGVSSTRMTPTESRTTSES 121

Query: 1255 SSDKDQM------TISLGKTPRTMEVTEMSPSKN---------------SFISYSRGTPS 1293
            +SD   +        S   TP   +V   +PS+                SF +Y+  T  
Sbjct: 122  TSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYK 181

Query: 1294 LEMTDTGFPETTKISSHQTHSPSEIPLGTPSDGN--------------------LASSPT 1333
            ++M+      T   SS  T   + IP  T S+G+                    L ++P 
Sbjct: 182  VDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPV 241

Query: 1334 SGSTQITPTLTSSNT----VGVHIPEMSTSLGKTALPSQALTITTFLCPEKESTSALPAY 1389
              ST +T +  +S++     G  +   + S G T L    L++   +  E  + S  PA 
Sbjct: 242  EISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAA 301

Query: 1390 T-------------PRTVE--MIVNSTYVTHSVSY-GQDTSFVDTTTSSSTRIS-NPMDI 1432
            T             P T E   I  STY   S        S +   TS  + +S  P+D 
Sbjct: 302  TNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDT 361

Query: 1433 N---TTFSHLHSLRTQPEVTS-VASFISEST---QTFPESLSLSTAGLYNDGFTVLSDR- 1484
            +   TT +   SL T  E TS + S +SE +      P S  L  +   +   T+  D  
Sbjct: 362  STLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSK 421

Query: 1485 --ITTAFSVPNVPTMLPRESSMATSTP---IYQMSSLPVNVT------------------ 1521
              +TTA    + PT    ++S+ATSTP      ++S+PV+ T                  
Sbjct: 422  TFVTTASEASSSPT-TAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSK 480

Query: 1522 --AFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTATSGPMSEMSSIPVNNS-AFTPATVS 1578
                TS + S +PP     S  T  P    +P T+ S     +S++PV +S A T +T  
Sbjct: 481  TQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMS-----VSTMPVASSEASTLSTTP 535

Query: 1579 SDTSTRVGLFSTLLSSVT-------PRTTMTMQTSTLDVTPV-------IYAGATSKNKM 1624
             DTST V   S   SS T       P +T +  ++ L   PV         A  TS    
Sbjct: 536  VDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPA 595

Query: 1625 VSSAFTTEMIEAPSRITPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSPLSSKS 1684
             S+ F T   EA S  + TT    + PT  + +   T     + T  V ++  S LS+  
Sbjct: 596  DSNTFVTTSSEASS--SSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTP 653

Query: 1685 TGAISSIPKTTFSPFLSATQQSSQADEATTLGILSGITNRSLSTVNSGTGVALT------ 1738
              + + +  +T +   S T + +    +T     + +T+  ++T    +  A T      
Sbjct: 654  VDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPV 713

Query: 1739 DTYSRITV-PENMLSPTHAD--SLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNT 1795
            DT + +T   E   SPT AD  S+ TS   + S  LTS   +       KT      ++T
Sbjct: 714  DTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVS-------KTLLTSSEAST 766

Query: 1796 RKMTSLLEKTSLTNYATSLNTPVSYPPWTPSSATLPSLTSFVYSPHSTEAEIS-TPKTSP 1854
               T L   T +T      +T  S  P T    ++P  T    SP  T   +S TP TSP
Sbjct: 767  LSTTPLDTSTHITT-----STEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSP 821

Query: 1855 PPTSQMV-----EFPVLGTRMTSSNTQPLLMTSWNIPT-AEG----SQFPISTTINVPTS 1904
              ++          PV  +   SS+  P   TS    T +EG    +  P+STT+   ++
Sbjct: 822  EASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSA 881

Query: 1905 NEMETETLHLVPGPLSTFTASQTGLVSKDVMAM-SSIPMSGILPNHGL--SENPSLSTSL 1961
                + T      P++  T +++   + +  +M +S P  G  P   +  S  P +S+  
Sbjct: 882  ISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEA 941

Query: 1962 RAITSTLADVKHTFEKMTTSVTPGTTLPSILSGATSGSVISKSPILTWLLSSLPS-GSPP 2020
            R +++T  D   T   +TTS T  T+ P+   G             T + +S PS G+ P
Sbjct: 942  RTLSATPVD---TSTPVTTS-TEATSSPTTAEG-------------TSIPTSTPSEGTTP 984

Query: 2021 ATVSNAPHVMTSSTVEVSKSTFLTSDMISAHPFTNLTTLPSATMSTILTRTIPTPTLGGI 2080
             T +   H + +++     ST  T+ + S  P T  T   S           P PT  G 
Sbjct: 985  LTSTPVSHTLVANS---EASTLSTTPVDSNTPLTTSTEASS-----------PPPTAEG- 1029

Query: 2081 TTGFPTSLPMSINVTDDIVYISTHPEASSRT-TITANPRTVSHP-SSFSRKTMSPSTTD- 2137
             T  PTS P   +     + +ST   ASS T T++  P   S P +++S+ + S +T D 
Sbjct: 1030 -TSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADG 1088

Query: 2138 -----HTLSVGAMPLPSSTITSSWNRIPTASSPSTLIIPKPTLDSLLNIMTTT------S 2186
                  T S G+ PL S  +++   R+  +S  STL      +D+ + + T+T      +
Sbjct: 1089 TSMPTSTYSEGSTPLTSVPVST---RLVVSSEASTL--STTPVDTSIPVTTSTEASSSPT 1143

Query: 2187 TVPGASFPLI--STGVTYPFTATVSSPISSFFETTWLDSTPSFLSTEASTSPTAT 2239
            T  G S P    S G T   +  VS+ +    E   L +TP    T+ +TS  A+
Sbjct: 1144 TAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEAS 1198


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score =  260 bits (664), Expect = 2e-68
 Identities = 513/2135 (24%), Positives = 864/2135 (40%), Gaps = 262/2135 (12%)

Query: 250  TTPSQITGVKPQNTAHSSTLL---------SQSIPIFATDYTTISYSNTTSPPLETMTAQ 300
            TTP  +T     +T H+S LL          Q+ P+  TD +++S ++ T  P+  +++ 
Sbjct: 1726 TTPLPVTSPSSASTGHASPLLVTDASSASTGQATPLPVTDTSSVSTAHATPLPVTGLSSA 1785

Query: 301  KILKTLVDETATFAVDVLSTSS---AISLPTQSISIDNT--TNSMKKTKSPSSESTKTTK 355
                   D+T    V  +S++S   AI LP  S S  +T  T  +  T + S+ +  TT 
Sbjct: 1786 S-----TDDTTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTTPLPVTDASSASTGDTTS 1840

Query: 356  MVEAMATEIFQ------PPTPSNFLSTSRFTKNSVVSTTSAIKSQSA---VTKTTSLFST 406
            +   + +          P T ++ +ST   T   V   +S     +    VT T S  ST
Sbjct: 1841 LPVTIPSSASSGHTTSLPVTDASSVSTGHATSLLVTDASSVSTGDTTPLPVTDTNSA-ST 1899

Query: 407  IESTSMSTTPCLKQKSTNTGALPISTAGQEFIESTAAGTVPWFTVEKTSPASTHVGTASS 466
             ++T +  T      + +  +LP+++       ++   T P   +  TSP+S   G  + 
Sbjct: 1900 GDTTPLHVTDASSVSTGHATSLPVTSLSS----ASTGDTTP---LPVTSPSSASSGHTTP 1952

Query: 467  FPPE-----PVLISTAAPV-DSVFPRNQTAFPLATTDMKIAFTVHSLTLP---TRLIETT 517
             P       P   +T+ PV D+       A PL  TD     T H+  LP   T  + T 
Sbjct: 1953 LPVTDASSVPTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPVTDTSSVSTG 2012

Query: 518  PAPRTAETELTSTNFQDVSLPRVEDAMSTSMSKETSSKTFSFLTSFSFTGTESVQTVIDA 577
             A     T L+S +  D +   V D  S S  ++T     S L+S S   T  +     +
Sbjct: 2013 QATPLPVTSLSSASTGDTTPLPVTDTSSASTGQDTPLPVTS-LSSVSTGDTTPLPVTSPS 2071

Query: 578  EATRTALTPEITLASTVAETMLSSTITGRVYTQNTPTADGHLLTLMSTRSASTSKAPESG 637
             A+    TP   L  T A ++ +   T  + T  +  + GH   L  T ++S S    + 
Sbjct: 2072 SASTGHATP---LLVTDASSVSTGHATSLLVTDASSVSTGHATALHVTDASSLSTGDTTP 2128

Query: 638  PTSTTDEAAHLFSSNETIWTSRPDQALLASMNTTTILTFVPNENFTSAFHENTTYTEYLS 697
               T+  +A   S+ +T      D + +++ + T+ L      + ++    +   T+  S
Sbjct: 2129 LPVTSPSSA---STGDTTPLPVTDTSSVSTGHATS-LPVTDTSSASTGHATSLPVTDTSS 2184

Query: 698  ATT-NITPLKASPEGKGTTANDATTARYTTAVSKLTS---PWFANFSIVSGTTSITNMPE 753
            A+T + TPL  +     +T   AT    T+  S  T    P     +  + T   T +P 
Sbjct: 2185 ASTGHATPLPVTDTSSASTGQ-ATPLPVTSPSSASTGHAIPLLVTDTSSASTGQATPLPV 2243

Query: 754  FKLTTLLL-KTIPM--------STKPANELPLTPRETVVPSVDIISTLACIQPNFSTEES 804
              L++     T P+        ST  A  LP+T   +V  S    + L    P+ ++   
Sbjct: 2244 TSLSSASTGDTTPLPVTDASSVSTGHATSLPVTSLSSV--STGDTTPLPVTSPSSASTGH 2301

Query: 805  ASETTQTEINGAIVFGGTTTPVPKSATTQRLNATVTRKEATSHYLMRKSTIAAVAEVSPF 864
            A+    T+ + A     T  PV   ++    + T     + S      +T   V + S  
Sbjct: 2302 ATPLHVTDASSASTGHATPLPVTSLSSASTGDTTPLPVTSPSSASTGHATPLHVTDASSV 2361

Query: 865  STMLEVTDESAQRVTASVTVSS-------FPDIEKLST----PL---DNKTATTEVRESW 910
            ST     D +   VT+S + SS         D    ST    PL   D  +A+T      
Sbjct: 2362 ST----GDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTTPLPVTDTSSASTGHATHL 2417

Query: 911  LLTKLVKTTPRSSYNEMTEMFNFNHTYVAHWTSETSEGISAGSPTSGSTHIFGEPLGAST 970
             +T L      +S  + T +   N +  +   +      S  S ++G T     PL  + 
Sbjct: 2418 PVTGLSS----ASTGDTTRLPVTNVSSASTGHATPLPVTSTSSASTGDT----TPLPGTD 2469

Query: 971  TRISETSFSTTPTDRTATSLSDGILPPQPTAAHSSA-----TPVPVTHMFS--------L 1017
            T    T  +T      A+S+S G     P  + SSA     TP+PVT   S        L
Sbjct: 2470 TSSVSTGHTTPLLVTDASSVSTGDTTRLPVTSPSSASTGHTTPLPVTDTPSASTGDTTPL 2529

Query: 1018 PVNGSSVVAEE--TEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVPPLDQTAST-T 1074
            PV  +S ++    T + ++ PS+ +   +TS+    ++ +ST   T L      +AST  
Sbjct: 2530 PVTNASSLSTRHATSLHVTSPSSASTGHATSLPVTDTSAASTGHATPLPVTSTSSASTGD 2589

Query: 1075 IVIVPTHGDLIRTTSEATVISVRKTSMAVPS------LTETPFHSLRLSTPV---TAKAE 1125
               +P       +T +AT + V  TS A         +T+T   S   +TP+      + 
Sbjct: 2590 TTPLPVTDTYSASTGQATPLPVTDTSSASTGDTTPLPVTDTSSASTGHATPLPVTNTSSV 2649

Query: 1126 TTLFSTSVDTVTPSTHTLVCSKPPPDNIPPASSTHVISTTSTPEATQPISQVEETSTYAL 1185
            +T  +T +   +PS+ +   + P P  +  ASS      TS P            ++  +
Sbjct: 2650 STGHATPLHVTSPSSASTGHTTPLP--VTDASSVSTGHATSLPVTDASSVFTGHATSLPV 2707

Query: 1186 SFPYTFSGGGVV-------ASLATG-TTETSVVDETTPSHISANKLTTSVNSHISSSATY 1237
            + P + S G          +S++TG  T   V D ++ S   A  L  +  S +S+    
Sbjct: 2708 TIPSSASSGHTTPLPVTDASSVSTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHA- 2766

Query: 1238 RVHTPVSIQLVTSTSVLSSDKDQMTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMT 1297
               TP  + L + +SV + D   + ++   +  T + T +  +  S +S    TP L +T
Sbjct: 2767 ---TP--LPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTP-LPVT 2820

Query: 1298 DTGFPETTKISSHQTHSPSEIPLG--TP-SDGNLASSPTSGSTQITPTLTSSNTVGVHIP 1354
            DT    T   +S      S    G  TP  D + +S+ T  +T +  T TSS ++G    
Sbjct: 2821 DTSSASTGHATSLPVTDTSSASTGHATPLPDTDTSSASTGHATLLPVTDTSSASIG---- 2876

Query: 1355 EMSTSLGKTALPSQALTITTFLCPEKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTS 1414
              +TSL  T   S +    T L     S+++    TP  V         T S S G    
Sbjct: 2877 -HATSLPVTDTSSISTGHATPLHVTSPSSASTGHATPLPVTD-------TSSASTGHANP 2928

Query: 1415 F-VDTTTSSSTRISNPMDINTTFSHLHSLRTQPEVTSVASFISESTQTFPESLSLSTAGL 1473
              V + +S+ST  + P+ +  T S      T   VTS++S  +  T   P +   S +  
Sbjct: 2929 LHVTSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGDTTPLPVTSPSSAS-- 2986

Query: 1474 YNDGFTVLSDRITTAFSVPNVPTMLPRESSMATST------PIYQMSSL------PVNVT 1521
               G T       T+ +     T LP  S+ + ST      P+   SS       P+ VT
Sbjct: 2987 --TGHTTPLPVTDTSSASTGQATALPVTSTSSASTGDTTPLPVTDTSSASTGQATPLPVT 3044

Query: 1522 AFTSKKVSDTPPIVITK--SSKTMH--PGCLKSPCTATSG-----PMSEMSSIPVNNSAF 1572
            + +S    DT P+ +T   S+ T H  P  +    +A++G     P++ +SS+   ++  
Sbjct: 3045 SLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLPVTSLSSVSTGDT-- 3102

Query: 1573 TPATVSSDTSTRVGLFSTLLSSVTPRTTMTMQTSTLDVTPVIYAGATSKNKMVSSAFTTE 1632
            TP  V+S +S   G  +T L      +  T  T++L VT              SSA+T +
Sbjct: 3103 TPLPVTSPSSASTG-HATSLPVTDTSSASTGDTTSLPVTDT------------SSAYTGD 3149

Query: 1633 MIEAPSRITPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSPLSSKSTGAISSIP 1692
                P  +T T+  S T  T P + T  +++  G  TP + T A    SS STG  + + 
Sbjct: 3150 TTSLP--VTDTSS-SSTGDTTPLLVTETSSVSTGHATPLLVTDA----SSASTGHATPLH 3202

Query: 1693 KTTFSPFLSATQQSSQADEATTLGILSG------ITNRSLSTVNSGTGVALTDTYSRITV 1746
             T  SP  ++T  ++      T  + +G      +T  S ++    T + +TD  S  T 
Sbjct: 3203 VT--SPSSASTGDTTPVPVTDTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDISSASTG 3260

Query: 1747 PENMLSPTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLLEKTS 1806
                L  T+  S+ T   + +   +TS  SAS         T+  S++T   T +   TS
Sbjct: 3261 QATPLPVTNTSSVSTGDTMPLP--VTSPSSASTGHATPLPVTSTSSASTGHATPV-PVTS 3317

Query: 1807 LTNYATSLNTPV--------SYPPWTPSSATLPSLTSFVYSPHSTEAEISTPKTSPPPTS 1858
             ++ +T   TP+        S    TP   T PS  S   + H+T   ++ P ++   T 
Sbjct: 3318 TSSASTGHTTPLPVTDTSSASTGDTTPLPVTSPSSAS---TGHTTPLHVTIPSSAS--TG 3372

Query: 1859 QMVEFPVLGTRMTSS-NTQPLLMTSWN-IPTAEGSQFPISTTINVPTSNEMETETLHLVP 1916
                 PV G    S+ +  PL +T  + + T   +  P+++  +V T +          P
Sbjct: 3373 DTSTLPVTGASSASTGHATPLPVTDTSSVSTGHATPLPVTSLSSVSTGDT--------TP 3424

Query: 1917 GPLSTFTASQTGLVSK-DVMAMSSIPMSGILPNHGLSENPSLSTSLRAITSTLADVKHTF 1975
             P++  +++ TG  +   V ++SS+      P   +++  S+ST   A    + D     
Sbjct: 3425 LPVTDASSASTGQATPLPVTSLSSVSTGDTTPLL-VTDASSVSTG-HATPLPVTD----- 3477

Query: 1976 EKMTTSVTPGTTLPSILSGATSGSVISKSPILTWLLSSLPSG-SPPATVSNAPHVMT--S 2032
               T+S + G T    ++  +S S    +P+    LSS+ +G + P  V++A  V T  +
Sbjct: 3478 ---TSSASTGDTTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHA 3534

Query: 2033 STVEVSKSTFLTSDMISAHPFTNLTTLPSATMSTILTRTIPTPTLGGITTGFPTSLPMSI 2092
            + + V+ ++  ++   +  P T+ T+  S   +T L  TIP+ +  G TT  P +   S+
Sbjct: 3535 TPLPVTDTSSASTGDTTRLPVTD-TSSASTGQATPLPVTIPSSSSSGHTTPLPVTSTSSV 3593

Query: 2093 NVTDDIVYISTHPEASSRTTITANPRTVSHPSSFSRKTMSPSTTDHTLSVG-AMPLPSST 2151
            +         T P ++S   +T  P T +  +S    T    T   ++S G A PLP   
Sbjct: 3594 STGHVTPLHVTSPSSASTGHVTPLPVTSTSSASTGHATPLLVTDASSVSTGHATPLP--- 3650

Query: 2152 ITSSWNRIPTASSPST-LIIPKPTLDSLLNIMTTTSTVPGASFPLISTGVTYPFTATVSS 2210
                   +  ASS ST    P P  D+        + +P  S   +STG T P   T +S
Sbjct: 3651 -------VTDASSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDAS 3703

Query: 2211 PISSFFETTWLDSTPSFLST-EASTSPTATKSTVS 2244
              S+   T    + PS +ST +    P  + S+ S
Sbjct: 3704 SASTGHATPLPVTIPSSVSTGDTMPLPVTSPSSAS 3738



 Score =  259 bits (662), Expect = 3e-68
 Identities = 550/2240 (24%), Positives = 884/2240 (39%), Gaps = 351/2240 (15%)

Query: 250  TTPSQITGVKPQNTAHSSTLLSQSIPIFATDYTTISYSNTTSPPLETMTAQKILKTLVDE 309
            TTP  +T     +T H++       P+  TD +++S  + TS          +L T    
Sbjct: 2062 TTPLPVTSPSSASTGHAT-------PLLVTDASSVSTGHATS----------LLVTDASS 2104

Query: 310  TATFAVDVLSTSSAISLPTQSISIDNTTNSMKKTKSPSSESTKTTKMVEAMATEIFQPPT 369
             +T     L  + A SL T        T  +  T SPSS ST  T  +         P T
Sbjct: 2105 VSTGHATALHVTDASSLST------GDTTPLPVT-SPSSASTGDTTPL---------PVT 2148

Query: 370  PSNFLSTSRFTKNSVVSTTSAIKSQSA---VTKTTSLFSTIESTSMSTTPCLKQKSTNTG 426
             ++ +ST   T   V  T+SA    +    VT T+S  ST  +T +  T      +    
Sbjct: 2149 DTSSVSTGHATSLPVTDTSSASTGHATSLPVTDTSSA-STGHATPLPVTDTSSASTGQAT 2207

Query: 427  ALPISTAGQEFIESTAAGTVPWFTVEKTSPASTHVGTASSFPPEPVL-ISTAAPVDSVFP 485
             LP+++       S + G      V  TS AST   T     P PV  +S+A+  D+   
Sbjct: 2208 PLPVTSPS-----SASTGHAIPLLVTDTSSASTGQAT-----PLPVTSLSSASTGDTT-- 2255

Query: 486  RNQTAFPLATTDMKIAFTVHSLTLPTRLI------ETTPAPRTAETELTSTNFQDVSLPR 539
                  PL  TD     T H+ +LP   +      +TTP P T+ +  ++ +   +    
Sbjct: 2256 ------PLPVTDASSVSTGHATSLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPL---H 2306

Query: 540  VEDAMSTSMSKETSSKTFSFLTSFSFTGTESVQTVIDAEATRTALTPEITLASTVAETML 599
            V DA S S    T     S L+S S   T  +     + A+    TP   L  T A ++ 
Sbjct: 2307 VTDASSASTGHATPLPVTS-LSSASTGDTTPLPVTSPSSASTGHATP---LHVTDASSVS 2362

Query: 600  SSTITGRVYTQNTPTADGHLLTLMSTRSASTSKAPESGPTSTTDEAAHLFSSNETIWTSR 659
            +   T    T ++  + GH   L  T  AS++   ++ P   TD +    S++    T  
Sbjct: 2363 TGDTTPLPVTSSSSASSGHTTPLPVT-DASSASTGDTTPLPVTDTS----SASTGHATHL 2417

Query: 660  PDQALLASMNTTTILTFVPNENFTSAFHENTT---YTEYLSATT-NITPLKASPEGKGTT 715
            P   L ++    T  T +P  N +SA   + T    T   SA+T + TPL  +     +T
Sbjct: 2418 PVTGLSSASTGDT--TRLPVTNVSSASTGHATPLPVTSTSSASTGDTTPLPGTDTSSVST 2475

Query: 716  ANDATTARYTTAVSKLTSPWFANFSIVSGTTSITNMPEFKLTTLLLKTIPMSTKPANELP 775
             +  TT    T  S +++       + S +++ T       TT L  T   S    +  P
Sbjct: 2476 GH--TTPLLVTDASSVSTGDTTRLPVTSPSSASTGH-----TTPLPVTDTPSASTGDTTP 2528

Query: 776  LTPRETVVPSVDIISTLACIQPNFSTEESASETTQTEINGAIVFGGTTTPVPKSATTQRL 835
            L        S    ++L    P+ ++   A+    T+ + A    G  TP+P ++T+   
Sbjct: 2529 LPVTNASSLSTRHATSLHVTSPSSASTGHATSLPVTDTSAAST--GHATPLPVTSTSSAS 2586

Query: 836  NATVTRKEATSHYLMRKSTIAAVAEVSPFSTMLEVTDESAQRVTASVTVSSFPDIEKLST 895
                T    T  Y       A+  + +P    L VTD S+   T   T     D    ST
Sbjct: 2587 TGDTTPLPVTDTYS------ASTGQATP----LPVTDTSSAS-TGDTTPLPVTDTSSAST 2635

Query: 896  ------PLDNKTATTEVRESWLLTKLVKTTPRSSYNEMTEMFNFNHTYVAHWTSETSEGI 949
                  P+ N ++ +        T L  T+P S+    T              S  S G 
Sbjct: 2636 GHATPLPVTNTSSVSTGHA----TPLHVTSPSSASTGHTTPLPVTDA------SSVSTGH 2685

Query: 950  SAGSPTSGSTHIFGEPLGASTTRI--SETSFSTTPTDRT-ATSLSDGILPPQPTAAHSS- 1005
            +   P + ++ +F     +    I  S +S  TTP   T A+S+S G     P    SS 
Sbjct: 2686 ATSLPVTDASSVFTGHATSLPVTIPSSASSGHTTPLPVTDASSVSTGHATSLPVTDASSV 2745

Query: 1006 ----ATPVPVT--------HMFSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSN 1053
                ATP+PVT        H   LP+   S V+      +    T + +   +    V++
Sbjct: 2746 STGHATPLPVTDASSVSTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTS 2805

Query: 1054 LSS-TTMTTALVPPLDQTASTT--IVIVPTHGDLIRTTSEATVISVRKTSMAVPS----- 1105
            LSS +T  T  +P  D ++++T     +P       +T  AT +    TS A        
Sbjct: 2806 LSSVSTGDTTPLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPDTDTSSASTGHATLL 2865

Query: 1106 -LTETPFHSLRLST--PVTAKAE-TTLFSTSVDTVTPSTHTLVCSKPPPDNIPPASST-- 1159
             +T+T   S+  +T  PVT  +  +T  +T +   +PS+ +   + P P     ++ST  
Sbjct: 2866 PVTDTSSASIGHATSLPVTDTSSISTGHATPLHVTSPSSASTGHATPLPVTDTSSASTGH 2925

Query: 1160 ----HVIS--TTSTPEATQ-PISQVEETST-YALSFPYTFSGGGVVASLATGTTETSVVD 1211
                HV S  + ST  AT  P++     ST +A   P T      ++S++TG  +T+ + 
Sbjct: 2926 ANPLHVTSPSSASTGHATPLPVTDTSSASTGHATPLPVTS-----LSSVSTG--DTTPLP 2978

Query: 1212 ETTPSHISANKLTTSVNSHISSSATYRVHTPVSIQLVTSTSVLSSDKDQMTISLGKTPRT 1271
             T+PS  S    T    +  SS++T +     ++ + +++S  + D   + ++   +  T
Sbjct: 2979 VTSPSSASTGHTTPLPVTDTSSASTGQA---TALPVTSTSSASTGDTTPLPVTDTSSAST 3035

Query: 1272 MEVTEMSPSKNSFISYSRGTP----SLEMTDTGFPETTKISSHQTHSPSEIPLGTPSDGN 1327
             + T +  +  S +S    TP    S     TG      ++   + S  +    TP    
Sbjct: 3036 GQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQ---ATPLPVT 3092

Query: 1328 LASSPTSGSTQITPTLTSSNTVGVHIPEMSTSLGKTALPSQALTITTFLCPEKESTSALP 1387
              SS ++G T   P  + S+    H    +TSL  T   S +   TT L P  +++SA  
Sbjct: 3093 SLSSVSTGDTTPLPVTSPSSASTGH----ATSLPVTDTSSASTGDTTSL-PVTDTSSA-- 3145

Query: 1388 AYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSS-STRISNPMDINTTFSHLHSLRTQP 1446
             YT  T  + V  T    S S G  T  + T TSS ST  + P+ +    S      T  
Sbjct: 3146 -YTGDTTSLPVTDT---SSSSTGDTTPLLVTETSSVSTGHATPLLVTDASSASTGHATPL 3201

Query: 1447 EVTSVASFISESTQTFP--ESLSLSTAGLYNDGFTVLSDRITTAFSVPNVPTMLPRESSM 1504
             VTS +S  +  T   P  ++ S+ST        T LS   T   +   V  +    +  
Sbjct: 3202 HVTSPSSASTGDTTPVPVTDTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDISSASTGQ 3261

Query: 1505 ATSTPIYQMSS------LPVNVTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTATSG- 1557
            AT  P+   SS      +P+ VT+ +S       P+ +T +S          P T+TS  
Sbjct: 3262 ATPLPVTNTSSVSTGDTMPLPVTSPSSASTGHATPLPVTSTSSASTGHATPVPVTSTSSA 3321

Query: 1558 --------PMSEMSSIPVNNSAFTPATVSSDTSTRVGLFSTLLSSVTPRTTMTMQTSTLD 1609
                    P+++ SS    ++  TP  V+S +S   G  +T L    P +  T  TSTL 
Sbjct: 3322 STGHTTPLPVTDTSSASTGDT--TPLPVTSPSSASTG-HTTPLHVTIPSSASTGDTSTLP 3378

Query: 1610 VTPVIYAGATSKNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTLPFVKTVPTTIMAGIVT 1669
            VT     GA+S     S+   T     P  +T T+ +S    T P   T  +++  G  T
Sbjct: 3379 VT-----GASS----ASTGHAT-----PLPVTDTSSVSTGHAT-PLPVTSLSSVSTGDTT 3423

Query: 1670 PFVGTTAFSPLSSKSTGAISSIPKTTFS--------PFLSATQQSSQADEATTLGILSGI 1721
            P   T A    SS STG  + +P T+ S        P L     S     AT L +    
Sbjct: 3424 PLPVTDA----SSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPV---- 3475

Query: 1722 TNRSLSTVNSGTGVALTDTYSRITVPENMLSPTHADSLHTSFNIQVSPSLTSFKSASGPT 1781
            T+ S ++    T + +TDT S  T     L  T   S+ T     +  +  S  S    T
Sbjct: 3476 TDTSSASTGDTTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHAT 3535

Query: 1782 K-NVKTTTNCFSSNTRKMTSLLEKTSLTNYATSLNTPVSYPPWTPSSATLP---SLTSFV 1837
               V  T++  + +T ++      ++ T  AT L  PV+ P  + S  T P   + TS V
Sbjct: 3536 PLPVTDTSSASTGDTTRLPVTDTSSASTGQATPL--PVTIPSSSSSGHTTPLPVTSTSSV 3593

Query: 1838 YSPHSTEAEISTPKTSPPPTSQMVEFPVLGTRMTSS-NTQPLLMT-SWNIPTAEGSQFPI 1895
             + H T   +++P ++   T  +   PV  T   S+ +  PLL+T + ++ T   +  P+
Sbjct: 3594 STGHVTPLHVTSPSSAS--TGHVTPLPVTSTSSASTGHATPLLVTDASSVSTGHATPLPV 3651

Query: 1896 STTINVPTSNEMETETLHLVPGPLSTFTASQTGLVSK-DVMAMSSIPMSGILPNHGLSEN 1954
            +   +  T +          P P++  +++ TG  +   V ++SS+      P   L   
Sbjct: 3652 TDASSASTGDT--------TPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTP---LPVT 3700

Query: 1955 PSLSTSLRAITSTLADVKHTFEKMTTSVTPGTTLPSILSGATSGSVISKSPILTWLLSSL 2014
             + S S    T     +        +SV+ G T+P  ++  +S S    +P+    LSS 
Sbjct: 3701 DASSASTGHATPLPVTIP-------SSVSTGDTMPLPVTSPSSASTGHATPLPVTGLSSA 3753

Query: 2015 PSGSP---PATVSNAPHVMTSSTVEVSKSTFLTSDMISAHPFTNL--------TTLP--- 2060
             +G     P T +++     ++ + V+ ++  ++D  +  P T++        T LP   
Sbjct: 3754 STGDTTPLPVTDTSSASTRHATPLPVTDTSSASTDDTTRLPVTDVSSASTGHATPLPVTS 3813

Query: 2061 SATMSTILTRTIPTPTLGGITTGFPTSLPMS------------INVTDDIVYISTHP--- 2105
            +++ ST  T  +P      ++TG  TSLP++            + VTD     + H    
Sbjct: 3814 TSSASTGDTTPLPVTDTSSVSTGHATSLPVTSRSSASTGHATPLPVTDTSSVSTGHATPL 3873

Query: 2106 ---EASSRTTITANPRTVSHPSSFSR---------KTMSPSTTDHT---------LSVG- 2143
                 SS +T  A P  V+ PSS S           T S ST D T         LS G 
Sbjct: 3874 PVTSTSSVSTGHATPLPVTSPSSASTGHATPVPVTSTSSASTGDTTPLPVTNASSLSTGH 3933

Query: 2144 AMPL----PSSTITSSWNRIPT--ASSPST---LIIPKPTLDSL-------LNIMTTTST 2187
            A PL    PSS      + +P   ASS ST     +P  +L S+       L +  T+S 
Sbjct: 3934 ATPLHVTSPSSASRGDTSTLPVTDASSASTGHATPLPLTSLSSVSTGDTTPLPVTDTSSA 3993

Query: 2188 VPGASFPL-------ISTGVTYPFTATVSSPISSFFETTWLDSTPSFLST-------EAS 2233
              G + PL       +STG T P   T+ S  SS   T+   +  S +ST         S
Sbjct: 3994 STGQATPLPVTSLSSVSTGDTTPLPVTIPSSASSGHTTSLPVTDASSVSTGHGTPLPVTS 4053

Query: 2234 TSPTATKSTVSFYNVEMSFSVFVEEPRIPITSVINEFTEN-------SLNSIFQNSEFSL 2286
            TS  +T  T      + S +       +P+T   +  T +       SL+S+       L
Sbjct: 4054 TSSASTGDTTPLPVTDTSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGHATPL 4113

Query: 2287 ATLETQIKSRDISEEEMVMD 2306
            A       S   S+  + M+
Sbjct: 4114 AVSSATSASTVSSDSPLKME 4133



 Score =  248 bits (632), Expect = 9e-65
 Identities = 528/2161 (24%), Positives = 829/2161 (38%), Gaps = 257/2161 (11%)

Query: 241  TTVSQQIDMTTPSQITGVKPQNTAHSSTLLSQSIPIFATDYTTISYSNTTSPPLE-TMTA 299
            TT     D+++ S    +    T+ SS     + P+  TD ++ S  +TTS P+    +A
Sbjct: 1790 TTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTTPLPVTDASSASTGDTTSLPVTIPSSA 1849

Query: 300  QKILKTLVDETATFAVDVLSTSSAISLPTQSISIDNTTN-SMKKTKSPSSESTKTTKMVE 358
                 T +  T   +V     +S +     S+S  +TT   +  T S S+  T    + +
Sbjct: 1850 SSGHTTSLPVTDASSVSTGHATSLLVTDASSVSTGDTTPLPVTDTNSASTGDTTPLHVTD 1909

Query: 359  AMATEIFQ----PPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFS--TIESTSM 412
            A +         P T  +  ST   T   V S +SA    +     T   S  T  +TS+
Sbjct: 1910 ASSVSTGHATSLPVTSLSSASTGDTTPLPVTSPSSASSGHTTPLPVTDASSVPTGHATSL 1969

Query: 413  STTPCLKQKSTNTGALPISTAGQEFIESTAAGTVPWFTVEKTSPASTHVGTASSFPPEPV 472
              T      + +   LP++ A      S + G      V  TS  ST   T     P PV
Sbjct: 1970 PVTDASSVSTGHATPLPVTDA-----SSVSTGHATPLPVTDTSSVSTGQAT-----PLPV 2019

Query: 473  L-ISTAAPVDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLI------ETTPAPRTA-- 523
              +S+A+  D+         PL  TD   A T     LP   +      +TTP P T+  
Sbjct: 2020 TSLSSASTGDTT--------PLPVTDTSSASTGQDTPLPVTSLSSVSTGDTTPLPVTSPS 2071

Query: 524  ------ETELTSTNFQDVSLPR-----VEDAMSTSMSKET-------SSKTFSFLTSFSF 565
                   T L  T+   VS        V DA S S    T       SS +    T    
Sbjct: 2072 SASTGHATPLLVTDASSVSTGHATSLLVTDASSVSTGHATALHVTDASSLSTGDTTPLPV 2131

Query: 566  TGTESVQT-------VIDAEATRTALTPEITLASTVAETMLSSTITGRVYTQNTPTADGH 618
            T   S  T       V D  +  T     + +  T + +   +T      T +  T    
Sbjct: 2132 TSPSSASTGDTTPLPVTDTSSVSTGHATSLPVTDTSSASTGHATSLPVTDTSSASTGHAT 2191

Query: 619  LLTLMSTRSASTSKA---PESGPTS-TTDEAAHLF-----SSNETIWTSRPDQALLASMN 669
             L +  T SAST +A   P + P+S +T  A  L      S++    T  P  +L ++  
Sbjct: 2192 PLPVTDTSSASTGQATPLPVTSPSSASTGHAIPLLVTDTSSASTGQATPLPVTSLSSAST 2251

Query: 670  TTTILTFVPNENFTSAFHENTTYTEYLS--ATTNITPLKASPEGKGTTANDATTARYTTA 727
              T    V + +  S  H  +     LS  +T + TPL  +     +T +   T  + T 
Sbjct: 2252 GDTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDTTPLPVTSPSSASTGH--ATPLHVTD 2309

Query: 728  VSKLTSPWFANFSIVSGTTSITNMPEFKLTTLLLKTIPMSTKPANELPLTPRETVVPSVD 787
             S  ++       + S +++ T       TT L  T P S    +  PL    T   SV 
Sbjct: 2310 ASSASTGHATPLPVTSLSSASTGD-----TTPLPVTSPSSASTGHATPL--HVTDASSVS 2362

Query: 788  IISTLACIQPNFSTEESASETTQTEINGAIVFGGTTTPVPKSATTQRLNATVTRKEAT-- 845
               T      + S+  S   T     + +    G TTP+P + T+       T    T  
Sbjct: 2363 TGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTTPLPVTDTSSASTGHATHLPVTGL 2422

Query: 846  SHYLMRKSTIAAVAEVSPFS----TMLEVTDESAQRVTASVTVSSFPDIEKLSTPLDNKT 901
            S      +T   V  VS  S    T L VT  S+   T   T     D   +ST      
Sbjct: 2423 SSASTGDTTRLPVTNVSSASTGHATPLPVTSTSSAS-TGDTTPLPGTDTSSVSTGHTTPL 2481

Query: 902  ATTEVR--ESWLLTKLVKTTPRSSYNEMTEMFNFNHTYVAHWTSETSEGISAGSPTS--- 956
              T+     +   T+L  T+P S+    T       T  A     T   ++  S  S   
Sbjct: 2482 LVTDASSVSTGDTTRLPVTSPSSASTGHTTPLPVTDTPSASTGDTTPLPVTNASSLSTRH 2541

Query: 957  -GSTHIFGEPLGASTTRISETSFSTTPTDRTATSLSDGILPPQPTAAHSSA-----TPVP 1010
              S H+   P  AST     TS   T T   +T    G   P P  + SSA     TP+P
Sbjct: 2542 ATSLHV-TSPSSASTGH--ATSLPVTDTSAAST----GHATPLPVTSTSSASTGDTTPLP 2594

Query: 1011 VTHMFS--------LPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTA 1062
            VT  +S        LPV  +S  +  T  T   P T   + ST   + +   ++++++T 
Sbjct: 2595 VTDTYSASTGQATPLPVTDTS--SASTGDTTPLPVTDTSSASTGHATPLPVTNTSSVSTG 2652

Query: 1063 LVPPLDQTASTTIVIVPTHGDLIRTTSEATVISVRKTSMAVPSLTETPFHSLRLSTPVTA 1122
               PL  T+ ++      H   +  T  ++V +   TS+ V   +   F     S PVT 
Sbjct: 2653 HATPLHVTSPSS--ASTGHTTPLPVTDASSVSTGHATSLPVTDASSV-FTGHATSLPVTI 2709

Query: 1123 KAETTLFSTSVDTVTPSTHTLVCSKPPPDNIPPASSTHVISTTSTPEATQPISQVEETST 1182
             +     S+   T  P T     S     ++P   ++ V +  +TP    P++     ST
Sbjct: 2710 PSSA---SSGHTTPLPVTDASSVSTGHATSLPVTDASSVSTGHATP---LPVTDASSVST 2763

Query: 1183 -YALSFPYTFSGGGVVASLATG-TTETSVVDETTPSHISANKLTTSVNSHISSSATYRVH 1240
             +A   P T      ++S++TG TT   V D ++ S   A  L  +  S +S+  T    
Sbjct: 2764 GHATPLPLT-----SLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDT---- 2814

Query: 1241 TPVSIQLVTSTSVLSSDKDQMTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTG 1300
            TP+ +   +S S  +     + ++   +  T   T +  +  S  S    T  L +TDT 
Sbjct: 2815 TPLPVTDTSSAS--TGHATSLPVTDTSSASTGHATPLPDTDTSSASTGHAT-LLPVTDTS 2871

Query: 1301 FPETTKISSHQTHSPSEIPLG--TPSDGNLASSPTSG-STQITPTLTSSNTVGVHIPEMS 1357
                   +S      S I  G  TP      SS ++G +T +  T TSS + G   P   
Sbjct: 2872 SASIGHATSLPVTDTSSISTGHATPLHVTSPSSASTGHATPLPVTDTSSASTGHANPLHV 2931

Query: 1358 TSLGKTALPSQALTITTFLCPEKESTSALPAY-TPRTVEMIVNSTYVTHSVSYGQDTSF- 1415
            TS      PS A T      P  +++SA   + TP  V  +        SVS G  T   
Sbjct: 2932 TS------PSSASTGHATPLPVTDTSSASTGHATPLPVTSL-------SSVSTGDTTPLP 2978

Query: 1416 VDTTTSSSTRISNPMDINTTFSHLHSLRTQPEVTSVASFISESTQTFP--ESLSLSTAGL 1473
            V + +S+ST  + P+ +  T S      T   VTS +S  +  T   P  ++ S ST   
Sbjct: 2979 VTSPSSASTGHTTPLPVTDTSSASTGQATALPVTSTSSASTGDTTPLPVTDTSSASTGQA 3038

Query: 1474 YNDGFTVLSDRITTAFSVPNVPTMLPRESSMATSTPIYQM--------SSLPVNVTAFTS 1525
                 T LS  ++T  + P +P   P  +S   +TP+            + P+ VT+ +S
Sbjct: 3039 TPLPVTSLSS-VSTGDTTP-LPVTSPSSASTGHATPLLVTDASSASTGQATPLPVTSLSS 3096

Query: 1526 KKVSDTPPIVITKSSKTMHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPATVSSDTSTRV 1585
                DT P+ +T  S         S   ATS P+++ SS    ++   P T   DTS+  
Sbjct: 3097 VSTGDTTPLPVTSPSSA-------STGHATSLPVTDTSSASTGDTTSLPVT---DTSSAY 3146

Query: 1586 GLFSTLLSSVTPRTTMTMQTSTLDVTPVIYAGATSKNKMVSSAFTTEMI------EAPSR 1639
               +T L       T T  +ST D TP++    +S    VS+   T ++       +   
Sbjct: 3147 TGDTTSLP-----VTDTSSSSTGDTTPLLVTETSS----VSTGHATPLLVTDASSASTGH 3197

Query: 1640 ITPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSPLSSKSTGAISSIPKTTFSPF 1699
             TP    SP+  +      VP T  + + T        + LSS STG  + +P T  S  
Sbjct: 3198 ATPLHVTSPSSASTGDTTPVPVTDTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDISS- 3256

Query: 1700 LSATQQSSQADEATTLGILSG------ITNRSLSTVNSGTGVALTDTYSRITVPENMLSP 1753
             ++T Q++      T  + +G      +T+ S ++    T + +T T S  T     +  
Sbjct: 3257 -ASTGQATPLPVTNTSSVSTGDTMPLPVTSPSSASTGHATPLPVTSTSSASTGHATPVPV 3315

Query: 1754 THADSLHTSFNIQVSPSLTSFKSASGPTK-NVKTTTNCFSSNTRKMTSLLEKTSLTNYAT 1812
            T   S  T     +  + TS  S    T   V + ++  + +T  +   +  ++ T   +
Sbjct: 3316 TSTSSASTGHTTPLPVTDTSSASTGDTTPLPVTSPSSASTGHTTPLHVTIPSSASTGDTS 3375

Query: 1813 SLNTPVSYPPWTPSSATLP-SLTSFVYSPHSTE------AEISTPKTSPPP--------T 1857
            +L    +    T  +  LP + TS V + H+T       + +ST  T+P P        T
Sbjct: 3376 TLPVTGASSASTGHATPLPVTDTSSVSTGHATPLPVTSLSSVSTGDTTPLPVTDASSAST 3435

Query: 1858 SQMVEFPVLG-TRMTSSNTQPLLMTSWN---------IPTAEGSQFPISTTINVPTSNEM 1907
             Q    PV   + +++ +T PLL+T  +         +P  + S      T  +P ++  
Sbjct: 3436 GQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTS 3495

Query: 1908 ETETLHLVPGPLSTFTASQTGLVSKDVMAMSSIPMSGILPNHGLSENPSLSTSLRAITST 1967
               T    P P+++ ++  TG  +  ++  +S   +G      +++  S ST      +T
Sbjct: 3496 SASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTG----DTT 3551

Query: 1968 LADVKHTFEKMTTSVTP-GTTLPSILSG--ATSGSVISKSPILTWLLSSL----PSGSPP 2020
               V  T    T   TP   T+PS  S    T   V S S + T  ++ L    PS +  
Sbjct: 3552 RLPVTDTSSASTGQATPLPVTIPSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTSPSSAST 3611

Query: 2021 ATVSNAPHVMTSSTVEVSKSTFLTSD--MISAHPFTNLTTLPSATMSTILTRTIPTPTLG 2078
              V+  P   TSS      +  L +D   +S    T L    +++ ST  T  +P     
Sbjct: 3612 GHVTPLPVTSTSSASTGHATPLLVTDASSVSTGHATPLPVTDASSASTGDTTPLPVTDTS 3671

Query: 2079 GITTGFPTSLPM----SINVTDDIVYISTHPEASSRTTITANPRTVSHPSSFSR-KTMS- 2132
              +TG  T LP+    S++  D      T  +ASS +T  A P  V+ PSS S   TM  
Sbjct: 3672 SASTGQATPLPVTSLSSVSTGDTTPLPVT--DASSASTGHATPLPVTIPSSVSTGDTMPL 3729

Query: 2133 PSTTDHTLSVG-AMPLP----SSTITSSWNRIP---TASSPSTLIIPKPTLDSLLNIMTT 2184
            P T+  + S G A PLP    SS  T     +P   T+S+ +    P P  D+       
Sbjct: 3730 PVTSPSSASTGHATPLPVTGLSSASTGDTTPLPVTDTSSASTRHATPLPVTDTSSASTDD 3789

Query: 2185 TSTVPGASFPLISTGVTYPFTATVSSPISSFFETTWLDSTPSFLSTEASTS-PTATKSTV 2243
            T+ +P       STG   P   T +S  S+   T    +  S +ST  +TS P  ++S+ 
Sbjct: 3790 TTRLPVTDVSSASTGHATPLPVTSTSSASTGDTTPLPVTDTSSVSTGHATSLPVTSRSSA 3849

Query: 2244 S 2244
            S
Sbjct: 3850 S 3850



 Score =  241 bits (615), Expect = 8e-63
 Identities = 514/2153 (23%), Positives = 823/2153 (38%), Gaps = 265/2153 (12%)

Query: 242  TVSQQIDMTTPSQITGVKPQNTAHSSTLLSQSIPIFATDYTTISYSNTTSPPLETMTAQK 301
            T S     TTP  +T     +T H++     S+P+  TD +++S  +TT  PL    A  
Sbjct: 1110 TSSVSTGHTTPLPVTDTSSASTGHAT-----SLPV--TDTSSVSTGHTT--PLHVTDASS 1160

Query: 302  ILKTLVDETATFAVDVLSTSSAISLPTQSISIDNTTNSMK-KTKSPSSES---------T 351
                             ST  A  LP  S+S  +T ++      SPSS S         T
Sbjct: 1161 ----------------ASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVT 1204

Query: 352  KTTKMVEAMATEIFQPPTPSNFLSTSRFTKNSVVSTTSAIKSQSA---VTKTTSLFSTIE 408
             T+      AT +  P T ++ +ST   T   V   ++A    +    VT T+S  ST +
Sbjct: 1205 DTSSASTGHATPL--PVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSA-STGQ 1261

Query: 409  STSMSTTPCLKQKSTNTGALPISTAGQEFIESTAAGTVPWFTVEKTSPASTHVGTASSFP 468
            +TS+  T      + +T  LP+++       +++A T     +  TSP+S   G A+   
Sbjct: 1262 ATSLLVTDTSSVSTGDTTPLPVTS-------TSSASTGHVTPLHVTSPSSASTGHAT--- 1311

Query: 469  PEPVLISTAAPVDSVFPRNQTA---------FPLATTDMKIAFTVHSLTLPTRLIETTPA 519
            P PV   ++A      P   T+          PL  TD     T H  T P  + + + A
Sbjct: 1312 PLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGH--TTPLHVTDASSA 1369

Query: 520  PRTAETELTSTNFQDVSLPRVEDAMSTSMSKETSSKTFSFL---TSFSFTGTESVQTVID 576
                 T L  T+   VS         TS S  ++      L   TS + TG  +   V D
Sbjct: 1370 STGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTD 1429

Query: 577  AEATRT--ALTPEITLASTVAE--------TMLSSTITGRVY------TQNTPTADGHLL 620
            A +  T  A +  +T+ S  +         T  SS  TG+        T +  T D   L
Sbjct: 1430 ASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPL 1489

Query: 621  TLMSTRSASTS-------KAPESGPTSTTDEAAHLFSSNETIWTSRPDQALLASMNTTTI 673
             + ST SAST         +P S  T           S+ +   + P      S  +T  
Sbjct: 1490 PVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGD 1549

Query: 674  LTFVPNENFTSAFHENTT---YTEYLSATT-NITPL---KASPEGKGTTANDATTARYTT 726
             T +P  + +S    +TT    T   SA+T + TPL     S   KG T     T+  + 
Sbjct: 1550 TTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSA 1609

Query: 727  AVSKLTS-PWFANFSIVSGTTS---ITNMPEFKL--TTLLLKTIPMSTKPANELPLTPRE 780
            +    T  P     S  +G T+   +TN         T L  T P S    +  PL    
Sbjct: 1610 STGHTTPLPVTDTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASTGHATPLPVTS 1669

Query: 781  TVVPSVDIISTLACIQPNFSTEESASETTQTEINGAIVFGGTTTPVP-------KSATTQ 833
            T   S    + L     + +T +  +    T+++ A    G  TP+P        +  T 
Sbjct: 1670 TSSASTGHATPLPVTGLSSATTDDTTRLPVTDVSSAST--GQATPLPVTSLSSVSTGDTT 1727

Query: 834  RLNATVTRKEATSHYLMRKSTIAAVAEVSPFSTMLEVTDESAQRVTASVTVSSFPDIEKL 893
             L  T     +T H      T A+ A     +T L VTD S+   TA  T      +   
Sbjct: 1728 PLPVTSPSSASTGHASPLLVTDASSASTGQ-ATPLPVTDTSSVS-TAHATPLPVTGLSSA 1785

Query: 894  STPLDNKTATTEV--RESWLLTKLVKTTPRSSYNEMTEMFNFNHTYVAHWTSETSEGISA 951
            ST    +   T+V    +     L  T+P S+    T          A     TS  ++ 
Sbjct: 1786 STDDTTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTTPLPVTDASSASTGDTTSLPVTI 1845

Query: 952  GSPTSGSTHIFGEPLGASTTRISETSFSTTPTDRTATSLSDGILPPQPTAAHSSATPVPV 1011
             S  S S H    P+  +++  +  + S   TD  A+S+S G   P P    +SA+    
Sbjct: 1846 PSSAS-SGHTTSLPVTDASSVSTGHATSLLVTD--ASSVSTGDTTPLPVTDTNSASTGDT 1902

Query: 1012 THMFSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVPPLDQTA 1071
            T     P++ +   +  T    S P T   + ST   + +   S ++ ++    PL  T 
Sbjct: 1903 T-----PLHVTDASSVSTGHATSLPVTSLSSASTGDTTPLPVTSPSSASSGHTTPLPVTD 1957

Query: 1072 STTIVIVPT-HGDLIRTTSEATVISVRKTSMAVPSLTETPFHSLRLSTPVTAKAETTLFS 1130
            +++   VPT H   +  T  ++V +   T + V   T+    S   +TP+     T   S
Sbjct: 1958 ASS---VPTGHATSLPVTDASSVSTGHATPLPV---TDASSVSTGHATPLPV---TDTSS 2008

Query: 1131 TSVDTVTPSTHTLVCSKPPPDNIP-PASSTHVIST-TSTPEATQPISQVE--ETSTYALS 1186
             S    TP   T + S    D  P P + T   ST   TP     +S V   +T+   ++
Sbjct: 2009 VSTGQATPLPVTSLSSASTGDTTPLPVTDTSSASTGQDTPLPVTSLSSVSTGDTTPLPVT 2068

Query: 1187 FPYTFSGGGVVASLATGTTETSVVDETTPSHISANKLTT--SVNSHISSSATYRVHTPVS 1244
             P + S G     L T  +  S    T+     A+ ++T  +   H++ +++        
Sbjct: 2069 SPSSASTGHATPLLVTDASSVSTGHATSLLVTDASSVSTGHATALHVTDASSLSTGDTTP 2128

Query: 1245 IQLVTSTSVLSSDKDQMTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPET 1304
            + + + +S  + D   + ++   +  T   T +  +  S  S    T SL +TDT    T
Sbjct: 2129 LPVTSPSSASTGDTTPLPVTDTSSVSTGHATSLPVTDTSSASTGHAT-SLPVTDTSSAST 2187

Query: 1305 --------TKISSHQTHSPSEIPLGTPSDGNLASSPTSGSTQITPTLTSSNTVGVHIPEM 1356
                    T  SS  T   + +P+ +PS     S+ T  +  +  T TSS + G      
Sbjct: 2188 GHATPLPVTDTSSASTGQATPLPVTSPS-----SASTGHAIPLLVTDTSSASTG-----Q 2237

Query: 1357 STSLGKTALPSQALTITTFLCPEKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSF- 1415
            +T L  T+L S +   TT L      T A    T     + V S     SVS G  T   
Sbjct: 2238 ATPLPVTSLSSASTGDTTPL----PVTDASSVSTGHATSLPVTS---LSSVSTGDTTPLP 2290

Query: 1416 VDTTTSSSTRISNPMDINTTFSHLHSLRTQPEVTSVASFISESTQTFP-ESLSLSTAGLY 1474
            V + +S+ST  + P+ +    S      T   VTS++S  +  T   P  S S ++ G  
Sbjct: 2291 VTSPSSASTGHATPLHVTDASSASTGHATPLPVTSLSSASTGDTTPLPVTSPSSASTGHA 2350

Query: 1475 NDGFTVLSDRITTAFSVPNVPTMLPRESSMATSTPIYQMSSLPVNVTAFTSKKVSDTPPI 1534
                   +  ++T  + P     LP  SS + S+      + P+ VT  +S    DT P+
Sbjct: 2351 TPLHVTDASSVSTGDTTP-----LPVTSSSSASSG----HTTPLPVTDASSASTGDTTPL 2401

Query: 1535 VITKSSKTMHPGCLKSPCTA-TSGPMSEMSSIPVNNSA------FTPATVSSDTSTRVGL 1587
             +T +S          P T  +S    + + +PV N +       TP  V+S +S   G 
Sbjct: 2402 PVTDTSSASTGHATHLPVTGLSSASTGDTTRLPVTNVSSASTGHATPLPVTSTSSASTG- 2460

Query: 1588 FSTLLSSVTPRTTMTMQTSTLDVTPV--IYAGATSKNKMV--SSAFTTEMIEAPSRITPT 1643
             +T L      +  T  T+ L VT    +  G T++  +   SSA T      P   TP+
Sbjct: 2461 DTTPLPGTDTSSVSTGHTTPLLVTDASSVSTGDTTRLPVTSPSSASTGHTTPLPVTDTPS 2520

Query: 1644 TFLSPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSPLSSKSTGAISSIPKTTFS------ 1697
                 T P       +P T  + + T    +   +  SS STG  +S+P T  S      
Sbjct: 2521 ASTGDTTP-------LPVTNASSLSTRHATSLHVTSPSSASTGHATSLPVTDTSAASTGH 2573

Query: 1698 --PFLSATQQSSQADEATTLGILS------------GITNRSLSTVNSGTGVALTDTYSR 1743
              P    +  S+   + T L +               +T+ S ++    T + +TDT S 
Sbjct: 2574 ATPLPVTSTSSASTGDTTPLPVTDTYSASTGQATPLPVTDTSSASTGDTTPLPVTDTSSA 2633

Query: 1744 ITVPENMLSPTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLL- 1802
             T     L  T+  S+ T     +   +TS  SAS         T+  S +T   TSL  
Sbjct: 2634 STGHATPLPVTNTSSVSTGHATPL--HVTSPSSASTGHTTPLPVTDASSVSTGHATSLPV 2691

Query: 1803 --EKTSLTNYATSLNTPVSYPPWTPSSATLP---SLTSFVYSPHSTEAEISTPKTSPPPT 1857
                +  T +ATSL  PV+ P    S  T P   +  S V + H+T   ++    S   T
Sbjct: 2692 TDASSVFTGHATSL--PVTIPSSASSGHTTPLPVTDASSVSTGHATSLPVT--DASSVST 2747

Query: 1858 SQMVEFPVL-GTRMTSSNTQPLLMTSW-NIPTAEGSQFPISTTIN--------VPTSNEM 1907
                  PV   + +++ +  PL +TS  ++ T + +  P++ T +        +P ++  
Sbjct: 2748 GHATPLPVTDASSVSTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLS 2807

Query: 1908 ETETLHLVPGPLSTFTASQTGLVSKDVMAMSSIPMSG---ILPNHGLSENPSLSTSLRAI 1964
               T    P P++  +++ TG  +   +  +S   +G    LP+   S   +   +L  +
Sbjct: 2808 SVSTGDTTPLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPDTDTSSASTGHATLLPV 2867

Query: 1965 TST-LADVKHTFE---KMTTSVTPGTTLPSILSGATSGSVISKSPILTWLLSSLPSGSPP 2020
            T T  A + H        T+S++ G   P  ++  +S S    +P+     SS  +G   
Sbjct: 2868 TDTSSASIGHATSLPVTDTSSISTGHATPLHVTSPSSASTGHATPLPVTDTSSASTGH-- 2925

Query: 2021 ATVSNAPHVMTSSTVEVSKSTFLTSDMISAHPFTNLTTLPSATMSTILTRTIPTPTLGGI 2080
               +N  HV + S+     +T L     S+    + T LP  ++S++ T         G 
Sbjct: 2926 ---ANPLHVTSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVST---------GD 2973

Query: 2081 TTGFPTSLPMSINVTDDIVYISTHPEASSRTTITANPRTVSHPSSFSRKTMSPSTTDHTL 2140
            TT  P + P S +         T   ++S    TA P T +  +S    T  P T   + 
Sbjct: 2974 TTPLPVTSPSSASTGHTTPLPVTDTSSASTGQATALPVTSTSSASTGDTTPLPVTDTSSA 3033

Query: 2141 SVG-AMPLP----SSTITSSWNRIPTASSPSTL---IIPKPTLDSLLNIMTTTSTVPGAS 2192
            S G A PLP    SS  T     +P  S  S       P    D+        + +P  S
Sbjct: 3034 STGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLPVTS 3093

Query: 2193 FPLISTGVTYPFTATVSSPISSFFETTWLDSTPSFLSTEASTSPTATKSTVSF 2245
               +STG T P   T  S  S+   T+   +  S  ST  +TS   T ++ ++
Sbjct: 3094 LSSVSTGDTTPLPVTSPSSASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAY 3146



 Score =  241 bits (614), Expect = 1e-62
 Identities = 516/2172 (23%), Positives = 860/2172 (39%), Gaps = 293/2172 (13%)

Query: 250  TTPSQITGVKPQNTAHSSTLLSQSIPIFATDYTTISYSNTTSPPLETMTAQKILKTLVDE 309
            +T S    ++ Q+TA SS   +Q I   + ++ T S   T+    +T+T Q +  TL   
Sbjct: 46   STGSTTATLEGQSTAASSRTSNQDISASSQNHQTKSTETTSKAQTDTLT-QMMTSTLFSS 104

Query: 310  TATFAV------DVLSTSSAISLP----------TQSISIDNTTNSMKKTKSPSSE-STK 352
             +   V      D ++TS   S+           T + S D+T  + ++T +  +E ST 
Sbjct: 105  PSVHNVMETAPPDEMTTSFPSSVTNTLMMTSKTITMTTSTDSTLGNTEETSTAGTESSTP 164

Query: 353  TTKMVEAMATEIFQPPTPS---NFLSTSRFTKNSVVSTTSAIKSQ--SAVTKTTSLFSTI 407
             T  V   A +  Q  T S   +   TS  ++N    +T   +    S +T  T+   + 
Sbjct: 165  VTSAVSITAGQEGQSRTTSWRTSIQDTSASSQNHWTRSTQTTRESQTSTLTHRTTSTPSF 224

Query: 408  ESTSMSTTPCLKQKSTNTGALPISTAGQEFIESTAAGTVPWFTVEKTSPAST--HVGTAS 465
              +  + T  + QK++ +G    +T+    + +T+  T    TV  TS  ST  + G  S
Sbjct: 225  SPSVHNVTGTVSQKTSPSG--ETATSSLCSVTNTSMMTSEKITV-TTSTGSTLGNPGETS 281

Query: 466  SFPPEPVLIS-TAAPVDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETTP------ 518
            S P    L+  T+A + +  P  Q+    + T  +   T  S    T+ +ETT       
Sbjct: 282  SVPVTGSLMPVTSAALVTFDPEGQSPATFSRTSTQDT-TAFSKNHQTQSVETTRVSQINT 340

Query: 519  ----APRTAETELTSTN----FQDVSLPRVEDAMSTSMSKETSSKTFSFLTSFSFTGTES 570
                 P T  T L+S +       VS        +T+ S  + S TF   +      T  
Sbjct: 341  LNTLTPVTTSTVLSSPSGFNPSGTVSQETFPSGETTTSSPSSVSNTFLVTSKVFRMPTSR 400

Query: 571  VQTVIDAEATRTALTPEIT-LASTVAETMLSSTITGRVYTQNTPTADGHLLTLMSTRSAS 629
              T+ + E T  +++  I+ + S V+    S T++  +   + P           +  A 
Sbjct: 401  DSTLGNTEETSLSVSGTISAITSKVSTIWWSDTLSTALSPSSLPPKISTAFHTQQSEGAE 460

Query: 630  TSKAPESGPTSTTDEAAHLFSSNE-TIWTSRPDQALLASMNTTTILTFVPNENFTSAFHE 688
            T+  P    + +   +  +F+ +E T W S    +  +  +TT   T +P+ + T A   
Sbjct: 461  TTGRPHERSSFSPGVSQEIFTLHETTTWPS----SFSSKGHTTWSQTELPSTS-TGAATR 515

Query: 689  NTTYTEYLSATTNITPLKASPEGKGTTANDATTARYTTAVSKLTSPWF-ANFSIVSGTT- 746
              T          I  + +     G      T + ++T + K T       ++  +GTT 
Sbjct: 516  LVTGNPSTGTAGTIPRVPSKVSAIGEPGEPTTYSSHSTTLPKTTGAGAQTQWTQETGTTG 575

Query: 747  -SITNMPEFKLTTLLLKTIPMSTKPANELPLTPRETVVPSVD---IISTLACIQPNFSTE 802
             ++ + P + +T ++      S+ P  +   + + T  PS +   I ST    Q + +  
Sbjct: 576  EALLSSPSYSVTQMIKTATSPSSSPMLDRHTSQQITTAPSTNHSTIHSTSTSPQESPAVS 635

Query: 803  E----SASETTQTEINGAIVFGGTTTPVPKSATTQRLNATVTRKEATSHYLMRKSTIAAV 858
            +     A +TTQ       V   T T   K+ TT   + T +    +        TI+A 
Sbjct: 636  QRGHTQAPQTTQESQTTRSVSPMTDT---KTVTTPGSSFTASGHSPSEIVPQDAPTISAA 692

Query: 859  AEVSPFSTMLEVTDESAQRVTASVTVSSFPDIEKLSTPLDNKTATTEVRESWLLTKLVKT 918
               +P       T +       +  + + P     +      T+ ++     L   +V T
Sbjct: 693  TTFAP-----APTGDGHTTQAPTTALQAAPSSHDATLGPSGGTSLSKTGALTLANSVVST 747

Query: 919  --------TPRSSYNEMTEMFNFNHTYVAHWT-----SETSEGISAGSPTSGSTHIFGEP 965
                    T  S+           HT+ A  T     ++TSE  S+GS T+ +       
Sbjct: 748  PGGPEGQWTSASASTSPDTAAAMTHTHQAESTEASGQTQTSEPASSGSRTTSAGTATPSS 807

Query: 966  LGASTTRIS----------ETSFSTTPTDRTATSLSDGILPPQPTAAHSSATPVPVTHMF 1015
             GAS T  S           T FS+ P+  + T+ S   L     +A +S   +PV+   
Sbjct: 808  SGASGTTPSGSEGISTSGETTRFSSNPSRDSHTTQSTTEL----LSASASHGAIPVSTGM 863

Query: 1016 SLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVPPLDQTASTTI 1075
            +     SS+V      T+SE ST  R       S  ++ S++   TA +  + QT  T  
Sbjct: 864  A-----SSIVPGTFHPTLSEASTAGRPTGQ---SSPTSPSASPQETAAISRMAQTQRTR- 914

Query: 1076 VIVPTHGDLIRTTSEATVISVRKTSMAVPSLTETPFHSLRLSTPVTAKAETTLFSTSVDT 1135
                   D I   S+AT      T   VP  T     S  L++P T   ET   S S   
Sbjct: 915  --TSRGSDTISLASQAT-----DTFSTVPP-TPPSITSTGLTSPQT---ETHTLSPSGSG 963

Query: 1136 VTPSTHTLVCSKPPPDNIPPASST------HV--ISTTSTPEATQ-PISQVEETST-YAL 1185
             T +T  +  + P P     ++ST      HV   S+ ST  AT  P++     ST +  
Sbjct: 964  KTFTTALISNATPLPVTYASSASTGHTTPLHVTDASSVSTGHATPLPVTSPSSVSTGHTT 1023

Query: 1186 SFPYTFSGG---GVVASLATGTTETSVVDETTP------SHISANKLTTSVNSHISSSAT 1236
              P T +     G V  L   +  ++   ++TP      S  S   +T    + +SS++T
Sbjct: 1024 PLPVTDTSSESTGHVTPLPVTSFSSASTGDSTPLPVTDTSSASTGHVTPLPVTSLSSAST 1083

Query: 1237 YRVHTPVSIQLVTSTSVLSSDK----DQMTISLGKT----------PRTMEVTEMSPSKN 1282
                TP+ +   +S S   +      D  ++S G T            T   T +  +  
Sbjct: 1084 GDT-TPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLPVTDTSSASTGHATSLPVTDT 1142

Query: 1283 SFISYSRGTPSLEMTDTGFPET--------TKISSHQTHSPSEIPLGTPSDGNLASSPTS 1334
            S +S    TP L +TD     T        T +SS  T   + +P+ +PS     S+ T 
Sbjct: 1143 SSVSTGHTTP-LHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPS-----SASTG 1196

Query: 1335 GSTQITPTLTSSNTVGVHIP-----------EMSTSLGKTALPSQALTITTFLCPEKEST 1383
             +T +  T TSS + G   P           + +TSL  T +PS A T  T   P  +++
Sbjct: 1197 HATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVT-IPSAASTGHTTPLPVTDTS 1255

Query: 1384 SALPAYTPRTVEMIVNSTYVTHSVSYGQDTSF-VDTTTSSSTRISNPMDINTTFSHLHSL 1442
            S   A T +   ++V     T SVS G  T   V +T+S+ST    P+ + +  S     
Sbjct: 1256 S---ASTGQATSLLVTD---TSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGH 1309

Query: 1443 RTQPEVTSVASFISESTQTFP-ESLSLSTAGLYNDGFTVLSDRITTAFSVP-NVPTMLPR 1500
             T   VTS++S  +  T   P  S S ++ G         +  ++T  + P +V      
Sbjct: 1310 ATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLHVTDASSA 1369

Query: 1501 ESSMATSTPIYQMSSL------PVNVTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTA 1554
             +  AT  P+  +SS+      P+ VT+ +S       P+++T +S         S   A
Sbjct: 1370 STGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSA-------STGHA 1422

Query: 1555 TSGPMSEMSSIPVNNSAFTPATVSSDTS----TRVGLFSTLLSSVTPRTTM----TMQTS 1606
            T  P+++ SS+  +++   P T+ S  S    T + +  T  +S    T++    T   S
Sbjct: 1423 TPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVS 1482

Query: 1607 TLDVTPVIYAGATSKNKMVSSAFTTEMIEAPSRIT-------PTTFLS--PTEPTLPFVK 1657
            T D TP+     TS +   +   T   + +PS  +       P T LS   T  T+P   
Sbjct: 1483 TGDTTPL---PVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPV 1539

Query: 1658 TVPTTIMAGIVTPFVGTTAFSPLSSKSTGAISSIPKTTFSPFLSATQQSSQADEATTLGI 1717
            T P++   G  TP   T A    SS STG  + +P T  SP  ++T  ++      T   
Sbjct: 1540 TSPSSASTGDTTPLPVTDA----SSVSTGHTTPLPVT--SPSSASTGHTTPLPVTDTSSA 1593

Query: 1718 LSG------ITNRSLSTVNSGTGVALTDTYSRITVPENMLSPTHADSLHTSFNIQVSPSL 1771
              G      +T+ S ++    T + +TDT S  T     L  T+A SL T     +   +
Sbjct: 1594 SKGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGDTTPLPVTNASSLSTGHATPL--HV 1651

Query: 1772 TSFKSASGPTKNVKTTTNCFSSNTRKMTSLLEKTSLTNYATSLNTPVSYPPWTPSSATLP 1831
            TS  SAS         T+  S++T   T  L  T L++  T   T +  P    SSA+  
Sbjct: 1652 TSPSSASTGHATPLPVTSTSSASTGHATP-LPVTGLSSATTDDTTRL--PVTDVSSASTG 1708

Query: 1832 SLTSFVYSPHSTEAEISTPKTSPPPTSQMVEFPVLGTRMTSSNTQPLLMT-SWNIPTAEG 1890
              T     P ++ + +ST  T+P P +         +  ++ +  PLL+T + +  T + 
Sbjct: 1709 QATPL---PVTSLSSVSTGDTTPLPVTS-------PSSASTGHASPLLVTDASSASTGQA 1758

Query: 1891 SQFPISTTINVPTSNEMETETLHLVPGPLSTFTASQTGLVSKDVMAMS---SIPMSGILP 1947
            +  P++ T +V T++     T   V G  S  T   T L   DV + S   +IP+    P
Sbjct: 1759 TPLPVTDTSSVSTAH----ATPLPVTGLSSASTDDTTRLPVTDVSSASTGQAIPLPVTSP 1814

Query: 1948 NHGLSENPSLSTSLRAITSTLADVKHTFEKMTTSVTPGTTLPSILSGATSGSVISKSPIL 2007
            +   + + +      A +++  D       + +S + G T    ++ A+S S    + +L
Sbjct: 1815 SSASTGDTTPLPVTDASSASTGDTTSLPVTIPSSASSGHTTSLPVTDASSVSTGHATSLL 1874

Query: 2008 TWLLSSLPSGSP---PATVSNAP--------HVMTSSTVEVSKSTFLTSDMISAHPFTNL 2056
                SS+ +G     P T +N+         HV  +S+V    +T L    +S+    + 
Sbjct: 1875 VTDASSVSTGDTTPLPVTDTNSASTGDTTPLHVTDASSVSTGHATSLPVTSLSSASTGDT 1934

Query: 2057 TTLPSATMSTIL---TRTIPTPTLGGITTGFPTSLPMSINVTDDIVYISTHPEASSRTTI 2113
            T LP  + S+     T  +P      + TG  TSLP++              +ASS +T 
Sbjct: 1935 TPLPVTSPSSASSGHTTPLPVTDASSVPTGHATSLPVT--------------DASSVSTG 1980

Query: 2114 TANPRTVSHPSSFSRKTMSPSTTDHTLSVG---AMPLPSSTITSSWNRIPTASSPSTLII 2170
             A P  V+  SS S    +P     T SV    A PLP ++++S       AS+  T   
Sbjct: 1981 HATPLPVTDASSVSTGHATPLPVTDTSSVSTGQATPLPVTSLSS-------ASTGDT--T 2031

Query: 2171 PKPTLDSLLNIMTTTSTVPGASFPLISTGVTYPFTATVSSPISSFFETTWLDSTPSFLST 2230
            P P  D+        + +P  S   +STG T P   T  S  S+   T  L +  S +ST
Sbjct: 2032 PLPVTDTSSASTGQDTPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSVST 2091

Query: 2231 EASTSPTATKST 2242
              +TS   T ++
Sbjct: 2092 GHATSLLVTDAS 2103



 Score =  233 bits (593), Expect = 3e-60
 Identities = 512/2185 (23%), Positives = 826/2185 (37%), Gaps = 299/2185 (13%)

Query: 263  TAHSSTLLSQSIPIFATDYTTISYSNTTSPPLETMTAQKILKTLVDE-TATFAVDVLSTS 321
            T H +T    S    +  +TT  +S T  P   T  A +++       TA     V S  
Sbjct: 481  TLHETTTWPSSFS--SKGHTT--WSQTELPSTSTGAATRLVTGNPSTGTAGTIPRVPSKV 536

Query: 322  SAISLPTQSISIDNTTNSMKKTKSPSSESTKTTKMVEAMATEIFQPPTPSNFLSTSRFTK 381
            SAI  P +  +  + + ++ KT    ++ T+ T+        +   P+ S        T 
Sbjct: 537  SAIGEPGEPTTYSSHSTTLPKTTGAGAQ-TQWTQETGTTGEALLSSPSYSVTQMIKTATS 595

Query: 382  NSVVSTTSAIKSQSAVTKTTSLFSTIESTSMSTTPCLKQKSTNTGALPISTAGQEFIEST 441
             S         SQ   T  ++  STI STS S      Q+S        + A Q   ES 
Sbjct: 596  PSSSPMLDRHTSQQITTAPSTNHSTIHSTSTSP-----QESPAVSQRGHTQAPQTTQESQ 650

Query: 442  AAGTVPWFTVEKTSPASTHVGTASSFPPEPVLISTAAPVDSVFPRNQTAFPLATTDMKIA 501
               +V   T  KT        TAS   P  ++   A  + +      T  P  T D    
Sbjct: 651  TTRSVSPMTDTKTVTTPGSSFTASGHSPSEIVPQDAPTISAA----TTFAPAPTGDG--- 703

Query: 502  FTVHSLTLPTRLIETTPAPRTAETELTSTNFQDVSLPRVEDAMSTSMSKETSSKTFSFLT 561
               H+   PT  ++  P+   A                +  +  TS+SK T + T +   
Sbjct: 704  ---HTTQAPTTALQAAPSSHDAT---------------LGPSGGTSLSK-TGALTLANSV 744

Query: 562  SFSFTGTESVQTVIDAEATRTALTPEITLASTVAETMLSSTITGRVYTQNTPTADGHLLT 621
              +  G E   T   A  +     P+   A T      S+  +G+  T   P + G   T
Sbjct: 745  VSTPGGPEGQWTSASASTS-----PDTAAAMTHTHQAESTEASGQTQTSE-PASSGSRTT 798

Query: 622  LMSTRSASTSKAPESGPTSTTDEAAHLFSSNETIWTSRPDQALLASMNTTTILTF----- 676
               T + S+S A  SG T +  E     S   T ++S P +    + +TT +L+      
Sbjct: 799  SAGTATPSSSGA--SGTTPSGSEGIST-SGETTRFSSNPSRDSHTTQSTTELLSASASHG 855

Query: 677  -VP-NENFTSAFHENTTYTEYLSATTNITPLKASPEGKGTTANDATTARYTTAVSKLTSP 734
             +P +    S+    T +     A+T        P G+ +  + + + + T A+S++   
Sbjct: 856  AIPVSTGMASSIVPGTFHPTLSEAST-----AGRPTGQSSPTSPSASPQETAAISRMAQT 910

Query: 735  WFANFSIVSGTTSITNMPEFKLTTLLLKTIPMSTKPANELPLTPRETVVPS-------VD 787
                 S  S T S+ +      +T+   T P  T      P T   T+ PS         
Sbjct: 911  QRTRTSRGSDTISLASQATDTFSTVP-PTPPSITSTGLTSPQTETHTLSPSGSGKTFTTA 969

Query: 788  IISTLACIQPNFSTEESASETTQTEINGAI-VFGGTTTPVPKSAT-------TQRLNATV 839
            +IS    +   +++  S   TT   +  A  V  G  TP+P ++        T  L  T 
Sbjct: 970  LISNATPLPVTYASSASTGHTTPLHVTDASSVSTGHATPLPVTSPSSVSTGHTTPLPVTD 1029

Query: 840  TRKEATSHYLMRKSTIAAVAEVSPFSTMLEVTDESAQRVTASVTVSSFPDIEKLST---- 895
            T  E+T H      T  + A     ST L VTD S+   T  VT      +   ST    
Sbjct: 1030 TSSESTGHVTPLPVTSFSSASTGD-STPLPVTDTSSAS-TGHVTPLPVTSLSSASTGDTT 1087

Query: 896  PL---DNKTATTEVRESWLLTKL------------VKTTPRSSYNEMTEM-------FNF 933
            PL   D  +A+T    S  +T              V  T  +S    T +        + 
Sbjct: 1088 PLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLPVTDTSSASTGHATSLPVTDTSSVST 1147

Query: 934  NHTYVAHWTSETSEGISAGSP---TSGSTHIFGE--PLGASTTRISETSFSTTPTDRTAT 988
             HT   H T  +S      +P   TS S+   G+  PL  ++   + T  +T       +
Sbjct: 1148 GHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTS 1207

Query: 989  SLSDGILPPQPTAAHSSATPVPVTHMFSLPVNGSSVVA--EETEVTMSEPSTLARAFSTS 1046
            S S G   P P    + A+ V   H  SLPV   S  +    T + +++ S+ +   +TS
Sbjct: 1208 SASTGHATPLPV---TDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATS 1264

Query: 1047 VLSDVSNLSSTTMTTALVPPLDQTASTTIVIVPTHGDLIRTTSEATVISVRKTSMAVPSL 1106
            +L   ++  ST  TT L P    ++++T  + P H      TS ++  +   T + V SL
Sbjct: 1265 LLVTDTSSVSTGDTTPL-PVTSTSSASTGHVTPLH-----VTSPSSASTGHATPLPVTSL 1318

Query: 1107 TETPFHSLRLSTPVTAKAETTLFSTSVDTVTPSTHTLVCSKPPPDNIPPASSTHVISTTS 1166
            +        +  PVT+ +  +   T+   VT ++ ++      P ++  ASS      T 
Sbjct: 1319 SSASTGDT-MPLPVTSPSSASTGDTTPLPVTDAS-SVSTGHTTPLHVTDASSASTGQATP 1376

Query: 1167 TPEATQPISQVEETSTYALSFPYTFSGGGVVASLATGTTETSVVDETTPSHISANKLTT- 1225
             P  +       +T+   ++ P + S G     L T T+  S    T      A+ ++T 
Sbjct: 1377 LPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTD 1436

Query: 1226 ---SVNSHISSSATYRVHTPVSIQ-------------LVTSTSVLSS-DKDQMTISLGKT 1268
               S+   I S+A+    TP+ +              LVT TS +S+ D   + ++   +
Sbjct: 1437 HATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSS 1496

Query: 1269 PRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSPSEIPLG--TPSDG 1326
              T  VT +  +  S  S    TP L +T      T         SPS    G  TP   
Sbjct: 1497 ASTGHVTPLHVTSPSSASTGHATP-LPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPV 1555

Query: 1327 NLASSPTSGSTQITPTLTSSNTVGVHIPEM------STSLGKTA-----LPSQALTITTF 1375
              ASS ++G T   P  + S+    H   +      S S G T       PS A T  T 
Sbjct: 1556 TDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSASTGHTT 1615

Query: 1376 LCPEKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSF-VDTTTSSSTRISNPMDINT 1434
              P  +++SA    T  T   + N++    S+S G  T   V + +S+ST  + P+ + +
Sbjct: 1616 PLPVTDTSSASTGDT--TPLPVTNAS----SLSTGHATPLHVTSPSSASTGHATPLPVTS 1669

Query: 1435 TFSHLHSLRTQPEVTSVASFISESTQTFP--ESLSLSTAGLYNDGFTVLSDRITTAFSVP 1492
            T S      T   VT ++S  ++ T   P  +  S ST        T LS  ++T  + P
Sbjct: 1670 TSSASTGHATPLPVTGLSSATTDDTTRLPVTDVSSASTGQATPLPVTSLSS-VSTGDTTP 1728

Query: 1493 NVPTMLPRESS------------------MATSTPIYQMSSL------PVNVTAFTSKKV 1528
             +P   P  +S                   AT  P+   SS+      P+ VT  +S   
Sbjct: 1729 -LPVTSPSSASTGHASPLLVTDASSASTGQATPLPVTDTSSVSTAHATPLPVTGLSSAST 1787

Query: 1529 SDTPPIVITKSSKTMH----PGCLKSPCTATSG-----PMSEMSSIPVNNSAFTPATVSS 1579
             DT  + +T  S        P  + SP +A++G     P+++ SS    ++   P T+ S
Sbjct: 1788 DDTTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTTPLPVTDASSASTGDTTSLPVTIPS 1847

Query: 1580 DTST------------------RVGLFSTLLSSVTPRTTM------TMQTSTLDVTP--V 1613
              S+                     L  T  SSV+   T       T   ST D TP  V
Sbjct: 1848 SASSGHTTSLPVTDASSVSTGHATSLLVTDASSVSTGDTTPLPVTDTNSASTGDTTPLHV 1907

Query: 1614 IYAGATSKNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVG 1673
              A + S     S   T+    +    TP    SP+  +      +P T  + + T    
Sbjct: 1908 TDASSVSTGHATSLPVTSLSSASTGDTTPLPVTSPSSASSGHTTPLPVTDASSVPTGHAT 1967

Query: 1674 TTAFSPLSSKSTGAISSIPKTTFSPFLS--ATQQSSQADEATTLGILSGITNRSLSTVNS 1731
            +   +  SS STG  + +P T  S   +  AT        + + G  + +   SLS+ ++
Sbjct: 1968 SLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPVTDTSSVSTGQATPLPVTSLSSAST 2027

Query: 1732 G--TGVALTDTYSRITVPENMLSPTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTN 1789
            G  T + +TDT S  T  +  L  T   S+ T     +   +TS  SAS         T+
Sbjct: 2028 GDTTPLPVTDTSSASTGQDTPLPVTSLSSVSTGDTTPLP--VTSPSSASTGHATPLLVTD 2085

Query: 1790 CFSSNTRKMTSLL---EKTSLTNYATSLNT--------------PVSYPPWTPSSATLP- 1831
              S +T   TSLL     +  T +AT+L+               PV+ P    +  T P 
Sbjct: 2086 ASSVSTGHATSLLVTDASSVSTGHATALHVTDASSLSTGDTTPLPVTSPSSASTGDTTPL 2145

Query: 1832 --SLTSFVYSPHSTEAEISTPKTSPPPTSQMVEFPVLGTRMTSS-NTQPLLMTSWN-IPT 1887
              + TS V + H+T   ++   TS   T      PV  T   S+ +  PL +T  +   T
Sbjct: 2146 PVTDTSSVSTGHATSLPVTD--TSSASTGHATSLPVTDTSSASTGHATPLPVTDTSSAST 2203

Query: 1888 AEGSQFPISTTINVPTSNEM--------ETETLHLVPGPLSTFTASQTG----LVSKDVM 1935
             + +  P+++  +  T + +           T    P P+++ +++ TG    L   D  
Sbjct: 2204 GQATPLPVTSPSSASTGHAIPLLVTDTSSASTGQATPLPVTSLSSASTGDTTPLPVTDAS 2263

Query: 1936 AMS-----SIPMSGILPNHGLSENPSLSTSLRAITSTLADVKHTFEKMTTSVTPGTTLP- 1989
            ++S     S+P++ +         P   TS  + ++  A   H  +  + S    T LP 
Sbjct: 2264 SVSTGHATSLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLHVTDASSASTGHATPLPV 2323

Query: 1990 SILSGATSGSVISKSPILTWLLSSLPSG-SPPATVSNAPHVMTSSTVEVSKSTFLTSDMI 2048
            + LS A++G     +P+     SS  +G + P  V++A  V T  T  +  ++  +S   
Sbjct: 2324 TSLSSASTGDT---TPLPVTSPSSASTGHATPLHVTDASSVSTGDTTPLPVTS--SSSAS 2378

Query: 2049 SAHPFTNLTTLPSATMSTILTRTIPTPTLGGITTGFPTSLPM----SINVTDDIVYISTH 2104
            S H  T L    +++ ST  T  +P       +TG  T LP+    S +  D      T+
Sbjct: 2379 SGHT-TPLPVTDASSASTGDTTPLPVTDTSSASTGHATHLPVTGLSSASTGDTTRLPVTN 2437

Query: 2105 PEASSRTTITANPRTVSHPSSFSRKTMSPSTTDHTLSVG-AMPL----PSSTITSSWNRI 2159
              ++S    T  P T +  +S    T  P T   ++S G   PL     SS  T    R+
Sbjct: 2438 VSSASTGHATPLPVTSTSSASTGDTTPLPGTDTSSVSTGHTTPLLVTDASSVSTGDTTRL 2497

Query: 2160 PTASSPSTLIIPKPTLDSLLNIMTTTSTVPGASFPLISTGVTYPFTATVSSPISSFFETT 2219
            P  S  S                  T+ +P    P  STG T P   T +S +S+   T+
Sbjct: 2498 PVTSPSSAST-------------GHTTPLPVTDTPSASTGDTTPLPVTNASSLSTRHATS 2544

Query: 2220 WLDSTPSFLSTEASTSPTATKSTVS 2244
               ++PS  ST  +TS   T ++ +
Sbjct: 2545 LHVTSPSSASTGHATSLPVTDTSAA 2569



 Score =  189 bits (481), Expect = 3e-47
 Identities = 438/1803 (24%), Positives = 677/1803 (37%), Gaps = 269/1803 (14%)

Query: 240  STTVSQQIDMTTPSQITGVKPQNTAHSSTLLSQSIPIFATDYTTISYSNTTSPPLETMTA 299
            ++T S     TTP   T     +T H++       P+  TD +++S  +TT  P+ + ++
Sbjct: 2452 TSTSSASTGDTTPLPGTDTSSVSTGHTT-------PLLVTDASSVSTGDTTRLPVTSPSS 2504

Query: 300  QKILKTLVDETATFAVDVLSTSSAISLP---TQSISIDNTTNSMKKTKSPSSESTKTTKM 356
                 T    T     D  S S+  + P   T + S+     +     SPSS ST     
Sbjct: 2505 ASTGHT----TPLPVTDTPSASTGDTTPLPVTNASSLSTRHATSLHVTSPSSAST----- 2555

Query: 357  VEAMATEIFQPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFS--TIESTSMST 414
                AT +  P T ++  ST   T   V ST+SA    +     T  +S  T ++T +  
Sbjct: 2556 --GHATSL--PVTDTSAASTGHATPLPVTSTSSASTGDTTPLPVTDTYSASTGQATPLPV 2611

Query: 415  TPCLKQKSTNTGALPISTAGQEFIESTAAGTVPWFTVEKTSPAST------HVGTASSFP 468
            T      + +T  LP++        S + G      V  TS  ST      HV + SS  
Sbjct: 2612 TDTSSASTGDTTPLPVTDTS-----SASTGHATPLPVTNTSSVSTGHATPLHVTSPSSAS 2666

Query: 469  PEPVLISTAAPVDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIE------TTPAPRT 522
                         SV   + T+ P+  TD    FT H+ +LP  +        TTP P T
Sbjct: 2667 TGHTTPLPVTDASSVSTGHATSLPV--TDASSVFTGHATSLPVTIPSSASSGHTTPLPVT 2724

Query: 523  AETELTSTNFQDVSLPRVEDAMSTSMSKET-------SSKTFSFLTSFSFTGTESVQT-- 573
              + +++ +    SLP V DA S S    T       SS +    T    T   SV T  
Sbjct: 2725 DASSVSTGHA--TSLP-VTDASSVSTGHATPLPVTDASSVSTGHATPLPLTSLSSVSTGD 2781

Query: 574  --VIDAEATRTALTPEITLASTVAETMLSSTITGRV----YTQNTPTADGHLLTL--MST 625
               +    T +A T +   A+ +  T LSS  TG       T  +  + GH  +L    T
Sbjct: 2782 TTPLPVTDTSSASTGQ---ATPLPVTSLSSVSTGDTTPLPVTDTSSASTGHATSLPVTDT 2838

Query: 626  RSASTSKA---PESGPTSTTDEAAHLFSSNETIWTSRPDQALLASMNTTTILTFVPNENF 682
             SAST  A   P++  +S +   A L    +T   S      L   +T++I T       
Sbjct: 2839 SSASTGHATPLPDTDTSSASTGHATLLPVTDTSSASIGHATSLPVTDTSSIST-----GH 2893

Query: 683  TSAFHENTTYTEYLSATTNITPLKASPEGKGTT--ANDATTARYTTAVSKLTSPWFANFS 740
             +  H  +  +   ++T + TPL  +     +T  AN       ++A +   +P     +
Sbjct: 2894 ATPLHVTSPSS---ASTGHATPLPVTDTSSASTGHANPLHVTSPSSASTGHATPLPVTDT 2950

Query: 741  IVSGTTSITNMPEFKL-------TTLLLKTIPMSTKPANELPLTPRETVVPSVDIISTLA 793
              + T   T +P   L       TT L  T P S    +  PL   +T   S    + L 
Sbjct: 2951 SSASTGHATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGQATALP 3010

Query: 794  CIQPNFSTEESASETTQTEINGAIVFGGTTTPVP-------KSATTQRLNATVTRKEATS 846
                + ++    +    T+ + A    G  TP+P        +  T  L  T     +T 
Sbjct: 3011 VTSTSSASTGDTTPLPVTDTSSAST--GQATPLPVTSLSSVSTGDTTPLPVTSPSSASTG 3068

Query: 847  H---YLMRKSTIAAVAEVSPF------------STMLEVTDESAQRVTASVTVSSFPDIE 891
            H    L+  ++ A+  + +P             +T L VT  S+   T   T     D  
Sbjct: 3069 HATPLLVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSAS-TGHATSLPVTDTS 3127

Query: 892  KLSTPLDNKTATTEVRESWL--LTKL-VKTTPRSSYNEMTEMFNFNHTYVAHWTSETSEG 948
              ST        T+   ++    T L V  T  SS  + T +     + V+   +     
Sbjct: 3128 SASTGDTTSLPVTDTSSAYTGDTTSLPVTDTSSSSTGDTTPLLVTETSSVSTGHATPLLV 3187

Query: 949  ISAGSPTSGSTHIFGEPLGASTTRISETSFSTTPTDRTATS-LSDGILPPQPTAAHSSA- 1006
              A S ++G       PL  ++   + T   TTP   T TS +S G   P P    SSA 
Sbjct: 3188 TDASSASTGHA----TPLHVTSPSSASTG-DTTPVPVTDTSSVSTGHATPLPVTGLSSAS 3242

Query: 1007 ----TPVPVTHMFS--------LPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNL 1054
                T +PVT + S        LPV  +S V+  T  TM  P T   + ST   + +   
Sbjct: 3243 TGDTTRLPVTDISSASTGQATPLPVTNTSSVS--TGDTMPLPVTSPSSASTGHATPLPVT 3300

Query: 1055 SSTTMTTALVPPLDQTASTTIVIVPTHGDLIRTTSEATVISVRKTSMAVPSLTETPFHSL 1114
            S+++ +T    P+  T++++     T    +  TS A+        +  PS   T  H+ 
Sbjct: 3301 STSSASTGHATPVPVTSTSSASTGHTTPLPVTDTSSASTGDTTPLPVTSPSSASTG-HTT 3359

Query: 1115 RLSTPVTAKAETTLFSTSVDTVTPSTHTLVCSKPPPDNIPPASSTHV-------ISTTST 1167
             L   + + A T   ST   T   S  T   +  P  +    S+ H        +S+ ST
Sbjct: 3360 PLHVTIPSSASTGDTSTLPVTGASSASTGHATPLPVTDTSSVSTGHATPLPVTSLSSVST 3419

Query: 1168 PEATQ-PISQVEETST-YALSFPYTFSGGGVVASLATG-TTETSVVDETTPSHISANKLT 1224
             + T  P++     ST  A   P T      ++S++TG TT   V D ++ S   A  L 
Sbjct: 3420 GDTTPLPVTDASSASTGQATPLPVTS-----LSSVSTGDTTPLLVTDASSVSTGHATPLP 3474

Query: 1225 TSVNSHISSSATYRVHTPVSIQLVTSTSVLSSDK-DQMTISLGKTPRTMEVTEMSPSKNS 1283
             +  S  S+  T R+        VT TS  S+ +   + ++   +  T + T +  +  S
Sbjct: 3475 VTDTSSASTGDTTRLP-------VTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDAS 3527

Query: 1284 FISYSRGTPSLEMTDTGFPET--------TKISSHQTHSPSEIPLGTPSDGN-------- 1327
             +S    TP L +TDT    T        T  SS  T   + +P+  PS  +        
Sbjct: 3528 SVSTGHATP-LPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTPLP 3586

Query: 1328 LASSPTSGSTQITP---TLTSSNTVG--VHIPEMSTSLGKTA-----LPSQALTITTFLC 1377
            + S+ +  +  +TP   T  SS + G    +P  STS   T      L + A +++T   
Sbjct: 3587 VTSTSSVSTGHVTPLHVTSPSSASTGHVTPLPVTSTSSASTGHATPLLVTDASSVSTGHA 3646

Query: 1378 PEKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSS-STRISNPMDINTTF 1436
                 T A  A T  T  + V  T    S S GQ T    T+ SS ST  + P+ +    
Sbjct: 3647 TPLPVTDASSASTGDTTPLPVTDT---SSASTGQATPLPVTSLSSVSTGDTTPLPVTDAS 3703

Query: 1437 SHLHSLRTQPEVTSVASFISESTQTFP-ESLSLSTAG----LYNDGFTVLSDRITTAFSV 1491
            S      T   VT  +S  +  T   P  S S ++ G    L   G +  S   TT   V
Sbjct: 3704 SASTGHATPLPVTIPSSVSTGDTMPLPVTSPSSASTGHATPLPVTGLSSASTGDTTPLPV 3763

Query: 1492 PNVP-------TMLPRESSMATST------PIYQMSSL------PVNVTAFTSKKVSDTP 1532
             +         T LP   + + ST      P+  +SS       P+ VT+ +S    DT 
Sbjct: 3764 TDTSSASTRHATPLPVTDTSSASTDDTTRLPVTDVSSASTGHATPLPVTSTSSASTGDTT 3823

Query: 1533 PIVITKSSKTMHPGCLKSPCTATSG---------PMSEMSSIPVNNSAFTPATVSSDTST 1583
            P+ +T +S          P T+ S          P+++ SS+   ++   P T +S  ST
Sbjct: 3824 PLPVTDTSSVSTGHATSLPVTSRSSASTGHATPLPVTDTSSVSTGHATPLPVTSTSSVST 3883

Query: 1584 RVGLFSTLLSSVTPRT--------TMTMQTSTLDVTPVIYAGATSKNK---------MVS 1626
                   + S  +  T        T T   ST D TP+    A+S +            S
Sbjct: 3884 GHATPLPVTSPSSASTGHATPVPVTSTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPS 3943

Query: 1627 SAF-----TTEMIEAPSRIT------PTTFLSP--TEPTLPFVKTVPTTIMAGIVTPFVG 1673
            SA      T  + +A S  T      P T LS   T  T P   T  ++   G  TP   
Sbjct: 3944 SASRGDTSTLPVTDASSASTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPV 4003

Query: 1674 TTAFSPLSSKSTGAISSIPKTTFSPFLSATQQSSQADEATTLGILSG----ITNRSLSTV 1729
            T+    LSS STG  + +P T  S   S    S    +A+++    G    +T+ S ++ 
Sbjct: 4004 TS----LSSVSTGDTTPLPVTIPSSASSGHTTSLPVTDASSVSTGHGTPLPVTSTSSAST 4059

Query: 1730 NSGTGVALTDTYSRITVPENMLSPTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTN 1789
               T + +TDT S  T     L  T   S  T     +   +TS  S S         ++
Sbjct: 4060 GDTTPLPVTDTSSASTGHATPLPVTDTSSASTGHATPL--PVTSLSSVSTGHATPLAVSS 4117

Query: 1790 CFSSNTRKMTSLLEKTSLTNYATSLNT-----PVSYPPWTPSSATLPSLTSFVYSPHSTE 1844
              S++T    S L+  +      SL T       + PP T S   + ++ S      ST 
Sbjct: 4118 ATSASTVSSDSPLKMETPGMTTPSLKTDGGRRTATSPPPTTSQTIISTIPSTAMHTRSTA 4177

Query: 1845 AEI 1847
            A I
Sbjct: 4178 API 4180


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score =  229 bits (583), Expect = 4e-59
 Identities = 548/2199 (24%), Positives = 836/2199 (38%), Gaps = 361/2199 (16%)

Query: 235  TIQEKSTTVSQQIDMTTPSQITGVKPQNTAHSSTLLSQSIPIFATDYTTISYSNTTSPPL 294
            T+    T  S  ++ +TP+  +      T   ++  S  +   +T + +   S+ T+P  
Sbjct: 3094 TLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSP 3153

Query: 295  ETMTAQKILKTLVDETATFAVDVLSTSSAISLPTQSISIDNTT---NSMKKTKSPSSEST 351
               TA           A   V     S   S PT   S  +TT   +    T   S  +T
Sbjct: 3154 PGTTA-----------APVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGAT 3202

Query: 352  KTTKMVEAMATEIFQ-PPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVT---------KTT 401
             T       AT +    PT S   S S  T     STT+A  S+ + T          T 
Sbjct: 3203 GTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTL 3262

Query: 402  SLFSTIES--TSMSTTPCLKQKSTNTGALPISTAGQEFI-ESTAAGTVPWFTVEKTSPAS 458
            S  ST  S  +  STT   +  ST+T A P ST       ESTA+ + P  T    SP S
Sbjct: 3263 SPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGS 3322

Query: 459  THVGTASSFPPEPVLISTA--APVDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIET 516
            T   TASS  PE     +   +   ++ P N TA  L    ++ +  VHS T       +
Sbjct: 3323 T---TASSLGPESTTFHSGPGSTETTLLPDNTTASGL----LEASTPVHSSTGSPHTTLS 3375

Query: 517  TPAPRTAETELTSTNFQDVSLPRVEDAM--------------STSMSKETSSKTFSFLTS 562
                 T + E  ST FQ  S P  +D                +TS    +S+ T  F  S
Sbjct: 3376 PAGSTTRQGE--STTFQ--SWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSAS 3431

Query: 563  FSFTGTESVQTVIDAEATRTALTPEITLAST---VAETMLSSTITGRVYTQNTPTADG-- 617
             +  G     T + +    TA TP    ++T   V E+    +  G   T + P +D   
Sbjct: 3432 STTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTS 3491

Query: 618  ----HLLTLMSTRSASTSKAPESGPTSTTDEAAHLFSSNETIWTSRPDQA---------- 663
                   T  S+ + + S AP +      +  ++  S   T  T  PD +          
Sbjct: 3492 GRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEEST 3551

Query: 664  ------------LLASMNTTTILTFVPNENFTSAFHENTTYTEYLSATTNI-------TP 704
                        +L + +TT++L     E+ TS     +  T  L  +T         T 
Sbjct: 3552 ASHSSQDATGTIVLPARSTTSVLL---GESTTSPISSGSMETTALPGSTTTPGLSEKSTT 3608

Query: 705  LKASPEGKGTTANDATTARYTTAVSKLTSPWFANFSIVSGTTSITNMPEFKLTTLLLK-- 762
              +SP    TT + A+T     +    TS          G+T  T  P+   T  L +  
Sbjct: 3609 FHSSPRSPATTLSPASTTSSGVSEESTTS------HSRPGSTHTTAFPDSTTTPGLSRHS 3662

Query: 763  TIPMSTKPANELPLTPRETVVPSVDIISTLACIQPNFSTEESASETTQTEING----AIV 818
            T   S+  + +  L P  T        ST         T  S+S +T T ++     A+ 
Sbjct: 3663 TTSHSSPGSTDTTLLPASTTTSGSSQEST---------TSHSSSGSTDTALSPGSTTALS 3713

Query: 819  FGGTTTPVPKSATTQRLNATVTRKEATSHYLMRKSTIAAVAEVSPFSTMLEVTDESAQRV 878
            FG  +T    S  +   + T+     TS  ++  ST    +  SP +T+   +  S    
Sbjct: 3714 FGQESTTFHSSPGST--HTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQ 3771

Query: 879  TASVTVSSFPDIEKLSTPLDNKTATTEVRESWLLTKLVKTTPRSSYNEMTEMFNFNHTYV 938
              S    + P     +TP    TAT  V ES    +   +TP + +   +     +    
Sbjct: 3772 GESTAFQTHP-ASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKST 3830

Query: 939  AHWTSETSEGI---SAGSPTSGSTHIFGEPLGASTTRISETSFSTTPTDRTATSLSDGIL 995
               +S  + G    SA S TSG        +   +T I+    STT    +  S +    
Sbjct: 3831 IFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSS 3890

Query: 996  PPQPTAAHSSATPVPVTHMFSLPVNGSSVVAEE----TEVTMSEPSTLARAFSTSVLSDV 1051
            P  PT   S A+      M SL V   S  +      T  T+S  ST     S    +  
Sbjct: 3891 PRSPTTTLSPAS------MTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVY 3944

Query: 1052 SNLSSTTMTTALVPPLDQTAS------TTIVIVPTHGDLIRTTSEATVISVRKTSMAVPS 1105
            S+   +T TT    P   T S      TT    P        T ++T   + + S A P 
Sbjct: 3945 SSSPGSTETTVF--PRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPG 4002

Query: 1106 LTETPFHSL--RLSTPVTAKAETTLFSTSVDTVTP-----STHTLVCSKPPPDNIPPASS 1158
               +    L   L+T    +  TT  S+S  T T      ST + +  +  P  + P+S+
Sbjct: 4003 SPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSST 4062

Query: 1159 THVISTTSTPEATQPISQVEETSTYALSFPYTFSGGGVVASLATGTTETSVVDETTPSHI 1218
                 TT+ P +    S  E+++T+     YT S     A+L+  TT +S V E      
Sbjct: 4063 ----ETTTLPGSPTTPSLSEKSTTF-----YT-SPRSPDATLSPATTTSSGVSEE----- 4107

Query: 1219 SANKLTTSVNSHISSSATYRVHTPVSIQLVTSTSVLSSDKDQMTISLGKTPRTMEVTEMS 1278
                   S  SH    +T+    P S    T+TS LS +      S G T  T+     S
Sbjct: 4108 -------SSTSHSQPGSTHTTAFPDS----TTTSGLSQEPTTSHSSQGSTEATL-----S 4151

Query: 1279 PSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSPSEIPLGTPSDGNL-ASSPTSGST 1337
            P             S   +  G   TT  SS      + +P  T + G + AS+PT  ST
Sbjct: 4152 PG------------STTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSST 4199

Query: 1338 -QITPTLTSSNTVGVHIPEMSTSLGKTALPSQALTITTFLCPEKESTSALPAYTPRTVEM 1396
              +  TLT +++    + E ST+    + PS + T      P   ST+A+P     T   
Sbjct: 4200 GSLHTTLTPASSTSTGLQEESTTF--QSWPSSSDTT-----PSPPSTTAVPVEVSTTYHS 4252

Query: 1397 IVNSTYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINT----TFSHLHSLRTQPEVTSVA 1452
              +ST  TH   +   ++ +  +  S+T  S+P    T    T S    L  +P  + ++
Sbjct: 4253 RPSSTPTTH---FSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPIS 4309

Query: 1453 SFISESTQTFPESLSLSTAGLYNDGFTVLSDRITTAFSVPNVP--TMLPRES-SMATSTP 1509
            S    ST+T     S +TAGL        S++ TT +S P  P  T+ P  + S   S  
Sbjct: 4310 S---GSTETTALPGSTTTAGL--------SEKSTTFYSSPRSPDTTLSPASTTSSGVSEE 4358

Query: 1510 IYQMSSLP--VNVTAFTSKKVSDTPPIVITKSSKT-MHPGCLK---SPCTATSGPMSEMS 1563
                 S P  ++ TAF S   S T P V  +S+ +   PG      SP + T+  +   S
Sbjct: 4359 STTSHSRPGSMHTTAFPS---STTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPES 4415

Query: 1564 SIPVNNSAFTPATVSSDTSTRVGLF--STLLSSVT--PRTTMTMQTSTL----------- 1608
            +   ++   T  T+  D +T  GL   ST + S T  P TT++   ST            
Sbjct: 4416 TTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSW 4475

Query: 1609 ----DVTPVIYAGATSKNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTLPFVK---TVPT 1661
                D TP   A  T+ +  V  + T+    +PS  TPTT  S +  TL   +   TV +
Sbjct: 4476 PNSKDTTP---APPTTTSAFVELSTTSH--GSPSS-TPTTHFSASSTTLGRSEESTTVHS 4529

Query: 1662 TIMAGIVTPFVGTTAFSPLSSKSTGAISSIPKTTFSPFLSATQQSSQADEATTLGILSGI 1721
            + +A   TP    +  S L  +ST   SS   T    F  +   S + +E+TT       
Sbjct: 4530 SPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTS---HSS 4586

Query: 1722 TNRSLSTVNSGTGVALTDTYSRITVPENMLSPTHADSLHTSFNIQVSPSLTSFKSASG-- 1779
            T  ++S+  S T   + +  S  + P +  +    DS  TS   + S +  S + A+G  
Sbjct: 4587 TTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTI 4646

Query: 1780 --PTKNV------KTTTNCFSSNTRKMTSLLEKTSLTNYATSLNTPVSYPPWTPSSATLP 1831
              P ++       ++TT+  SS + + T+L   T+    +    T  S P  TP++    
Sbjct: 4647 VLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSA 4706

Query: 1832 SLTSFVYSPHSTEAEISTPKTSPPPTSQMVEFPVLGTRMTSSNTQPLLMTSWNIP---TA 1888
            S T+   S  ST    S   T+  P+        L    T+ ++ P    + + P   TA
Sbjct: 4707 SSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTA 4766

Query: 1889 EG-------SQFPISTTINVPTSNEM----ETETLHLVPGPLST--FTASQT--GLVSKD 1933
             G       S    + TI+ P S       E  + H  PG ++T  F  S T  G   + 
Sbjct: 4767 SGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEES 4826

Query: 1934 VMAMSSIPMSGI--LPNHGLSENPSLSTSLRAITSTLADVKHTFEKMTTSVTPGTTLPSI 1991
              + SS   +GI  LP H        +TS R   ST           T  ++PG+   ++
Sbjct: 4827 TASHSSPDTNGITPLPAH-------FTTSGRIAEST-----------TFYISPGSMETTL 4868

Query: 1992 LSGATSGSVISKSPILTWLLSSLPSGSPPATVSNAPHVMTSSTVEVSKSTFLTSDMISAH 2051
             S AT+  + +KS IL    SS  S SP  T+S  P  MTSS++   + T L S   S H
Sbjct: 4869 ASTATTPGLSAKSTIL---YSS--SRSPDQTLS--PASMTSSSIS-GEPTSLYSQAESTH 4920

Query: 2052 PFTNLTTLPSATMSTILTR-----------TIPTPTLGGITTGF-------PTSLPMSIN 2093
                 T  P++T ++ L++           T  T + G ITT         P S P S  
Sbjct: 4921 T----TAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSAL 4976

Query: 2094 VTDDIVYISTHPEASSRTTITANPRTV-----SHPSSFS----RKTMSPSTTDHTLSVGA 2144
             T      +    +   TT  ++P +      SH ++ S    + T  P +   T +V  
Sbjct: 4977 STVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTV-- 5034

Query: 2145 MPLPSSTITSSWNRIPTA---SSPSTLIIPKPTLDSLLNIMTTTSTVPGASFPLISTGVT 2201
              LP++  T+   +  TA   SS +T   P P   +  +++   +T        IS   T
Sbjct: 5035 --LPATLTTTDIGQESTAFHSSSDATGTTPLPARSTASDLVGEPTTF------YISPSPT 5086

Query: 2202 YPFTATVSSPISSFFE-TTWLDSTPSFLSTEASTSPTAT 2239
            Y      SS  S   E +T   ++PSF ST  ST    T
Sbjct: 5087 YTTLFPASSSTSGLTEESTTFHTSPSFTSTIVSTESLET 5125



 Score =  223 bits (569), Expect = 2e-57
 Identities = 536/2240 (23%), Positives = 834/2240 (37%), Gaps = 412/2240 (18%)

Query: 232  ENMTIQEKSTTVSQQIDMTTPSQITGVKPQNTAHSSTLLSQSIPIFATDYTTISYSNTTS 291
            E  T    STT +     +T S +  V+   + HSS          +T  T    S+TTS
Sbjct: 855  EESTTSHSSTTHTISSAPSTTSAL--VEEPTSYHSSP--------GSTATTHFPDSSTTS 904

Query: 292  PPLETMTAQKILKTLVDETATFAVDVLSTSSAISLPTQSISIDNTTNSMKKTKSPSSEST 351
               E  TA    +   D T T  +   ST+S   L  +S +   ++ SM+ T  P S  T
Sbjct: 905  GRSEESTASHSSQ---DATGTIVLPARSTTSV--LLGESTTSPISSGSMETTALPGS--T 957

Query: 352  KTTKMVEAMATEIFQPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFSTIESTS 411
             T  + E   T    P +P+  LS +  T + V   ++  +S+   T TT+   +  +  
Sbjct: 958  TTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPG 1017

Query: 412  MS---TTPCLKQKSTNTGALPISTAGQ-EFIESTAAGTVPWFTVEKTSPASTHVGTASSF 467
            +S   TT      ST+T  LP ST       EST + +    T    SP ST   TA SF
Sbjct: 1018 LSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGST---TALSF 1074

Query: 468  PPEPVLISTAAPVDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETTPAPRTAETEL 527
              E     +     +    + T FP +TT   I      +   TR+  +T +PRT     
Sbjct: 1075 GQESTTFHS-----NPGSTHTTLFPDSTTSSGI------VEASTRVHSSTGSPRTT---- 1119

Query: 528  TSTNFQDVSLPRVEDAMSTSMSKETSSKTFSFLTSFSFTGTESVQTVIDAEATRTALTPE 587
                        +  A STS   +  S  F                     +T T  +P 
Sbjct: 1120 ------------LSPASSTSPGLQGESTAFQ----------------THPASTHTTPSPP 1151

Query: 588  ITLASTVAETMLSSTITGRVYTQNTP---TADGHLLTLMSTRSASTSKAPESGPTSTTDE 644
             T  + V E+       G   T + P   T  GH     S +S     +P++  + TT  
Sbjct: 1152 STATAPVEESTTYHRSPGSTPTTHFPASSTTSGH-----SEKSTIFHSSPDA--SGTTPS 1204

Query: 645  AAHLFSSNETIWTSRPDQALLASMNTTTILTFVPNENFTSAFHENTT--YTEYLSATTNI 702
            +AH  +S       R +         +T +T +P    T    E +T  Y+   S TT +
Sbjct: 1205 SAHSTTSG------RGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTL 1258

Query: 703  TPLKASPEGKG----TTANDATTARYTTAVSKLTSPWFAN-----FSIVSGTTSITNMPE 753
            +P   +  G G    T+ +   +   T + +  T+P  +      +S   G+T  T  P 
Sbjct: 1259 SPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPH 1318

Query: 754  FKLTTL------LLKTIPMST------KPANELPLTPRETVVPS--------VDIISTLA 793
               T++         + P ST      + +    LT   T  P         +    T A
Sbjct: 1319 STTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTA 1378

Query: 794  CIQPNFSTEESASETTQTEINGAIVFGGTTTPVPKSATTQRLNATVTRKEA-----TSHY 848
             +    +T  S+S +T T+++ A     TT+ +   +T  RL+ + T         T+  
Sbjct: 1379 DLGEESTTFPSSSGSTGTKLSPA---RSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPS 1435

Query: 849  LMRKSTIAAVAEVSPFSTMLEVTDESAQRVTASVT---------VSSFPDIEKLSTPLDN 899
            L  KST    +  SP +T+   T  S+     S T          ++FPD    S     
Sbjct: 1436 LSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQE 1495

Query: 900  KTATTEVRESWLLTKLVKTTPRSSYNEMTEMFNFN----HTYVAHWTSETSEGISAGSPT 955
             T +   + S   T    +T  SS  + +  F+ +     T +    + TS  + A +PT
Sbjct: 1496 PTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPT 1555

Query: 956  ---SGSTHIFGEPLGASTTRISE--TSFSTTPTDRTATSLSDGILPPQPTAA-------- 1002
               +GS H    P  +++  + E  T+F + P+    T       PP  TAA        
Sbjct: 1556 HSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPS-----PPGTTAAPVEVSTTY 1610

Query: 1003 HSSATPVPVTHMFSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTA 1062
            HS  +  P TH FS         A  T +  SE ST   +            S     TA
Sbjct: 1611 HSRPSSTPTTH-FS---------ASSTTLGRSEESTTVHS------------SPGATGTA 1648

Query: 1063 LVPPLDQTASTTIVIVPTHGDLIRTTSEATVISVRKTSMAVPSLTETPFHSLRLSTPVTA 1122
            L P   ++A++ +V  PT   +   ++E T +    T+  +   + T + S R      +
Sbjct: 1649 LFPT--RSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLS 1706

Query: 1123 KAETTLFSTSVDTVTP-----STHTLVCSKPPPDNIPPASSTHVIS--------TTSTPE 1169
             A TT    S ++ T      STHT     P    +P  S     S        TT +P 
Sbjct: 1707 PASTTSSGVSEESTTSHSRPGSTHTTAF--PGSTTMPGVSQESTASHSSPGSTDTTLSPG 1764

Query: 1170 ATQPISQVEETSTYALSFPYTFSGGGVVASLATGTTETSVVDETTPSHISANKLTTSVNS 1229
            +T   S   E++T+     ++  G      L   TT + +++ +TP H S     T+++ 
Sbjct: 1765 STTASSLGPESTTF-----HSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSP 1819

Query: 1230 HISSSATYRVHTPVSIQLVTSTSVLSSDKDQMTISLGKTPRTMEVTEMSPSKNSFISYSR 1289
              + S T +  +       T+     S KD M      T   +E++          + S 
Sbjct: 1820 --AGSTTRQGES-------TTFQSWPSSKDTMPAPPTTTSAFVELS----------TTSH 1860

Query: 1290 GTPS-LEMTDTGFPETTKISSHQTHSPSEIPLGTPSDGNLASSPTSGSTQITPTLTSS-- 1346
            G+PS    T      TT   S ++ +    P+ T +  + A S TSG  + +    SS  
Sbjct: 1861 GSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPG 1920

Query: 1347 NTVGVHIPEMSTSLGKTALPSQALTITTFLCPEKESTSALPAYTPRTVEMIVNSTYVTHS 1406
            +T  +H PE ST+ G++     + + TT       ST++     P +      ST  TH 
Sbjct: 1921 STQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHF 1980

Query: 1407 VSYGQDTSFVDTTTSSSTRISNPMDINTTFSHLHSLRTQPEVTSVASFISESTQTFPESL 1466
                 D+S     +  ST   +  D   T          P  ++ +  + EST +   S 
Sbjct: 1981 ----PDSSTTSGRSEESTASHSSQDATGTI-------VLPARSTTSVLLGESTTSPISSG 2029

Query: 1467 SLSTAGLYNDGFTV-LSDRITTAFSVPNVPTMLPRESSMATSTPIYQMSSLPVNVTAFTS 1525
            S+ T  L     T  LS++ TT  S P  P          T +P    SS     +  + 
Sbjct: 2030 SMETTALPGSTTTPGLSEKSTTFHSSPRSPA--------TTLSPASTTSSGVSEESTTSH 2081

Query: 1526 KKVSDTPPIVITKSSKTMHPGCLKSPCTATSGPMS-EMSSIPVNNSAFTPATVSSDTSTR 1584
             +   T       S+ T  PG  +   T+ S P S + + +P + +   P+  S+ + + 
Sbjct: 2082 SRPGSTHTTAFPDSTTT--PGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSS 2139

Query: 1585 VGLFSTLLS-SVTPRTTMTMQTSTLDVTPVIYAGATSKNKMVSSAFTTEMIEAPSRI--- 1640
             G   T LS   T   +   +++T   +P    G+T       S  ++ ++EA +R+   
Sbjct: 2140 PGSTDTALSPGSTTALSFGQESTTFHSSP----GSTHTTLFPDSTTSSGIVEASTRVHSS 2195

Query: 1641 --TPTTFLSPTEPTLPFVKTVPTTIM----AGIVTPFVGTTAFSPLSSKSTGAIS--SIP 1692
              +P T LSP   T P ++   T       +   TP   +TA +P+   +T   S  S P
Sbjct: 2196 TGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTP 2255

Query: 1693 KTTF------------------SPFLSATQQSSQAD------EATTLGILSG---ITNRS 1725
             T F                  SP  S T  SS         E+TT  I  G   IT   
Sbjct: 2256 TTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLP 2315

Query: 1726 LSTVNSGTGVALTDTYSRITVPENMLSPTHADSLHT------------SFNIQVSP---- 1769
             ST   G   A T  YS    P   LSP    SL              S +  VSP    
Sbjct: 2316 GSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTT 2375

Query: 1770 -------SLTSFKSASG----------PTKNVK--TTTNCFSSNTRKMTSLLEKTSLTNY 1810
                   S T + S+ G          PT +V+    T   S      T+L  + S T+ 
Sbjct: 2376 TPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSG 2435

Query: 1811 ATSLNT-----PVSYPPWTPSSATLPSL----TSFVYSPHSTEAEIS------------- 1848
             T  +T     P S     P++ T   L    T+F  S  ST   +S             
Sbjct: 2436 LTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGES 2495

Query: 1849 TPKTSPPPTSQMVEFPVLGTRMTSSNTQPLLMTSWNIPTAEGSQFPISTTINVPTSNEME 1908
            TP    P +++    P   T  + S       TS   P A  S  P +TT +  +    E
Sbjct: 2496 TPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLS--PATTTSSGVSE---E 2550

Query: 1909 TETLHLVPGPLSTFT---ASQTGLVSKDVMAMSSIPMSG---ILP----NHGLSENPSLS 1958
            + T H  PG   T     ++ T  +S+      S P S    +LP      G S+  + S
Sbjct: 2551 SSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTS 2610

Query: 1959 TSLRAITSTLADVKHTF------EKMTTSVTPGTTLPSILSGATSGSVISKSPILTWLLS 2012
             S    T T      T       E  T   +PG+T  ++   +T+ S I ++   T + S
Sbjct: 2611 HSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEAS--TRVHS 2668

Query: 2013 SLPSGSPPATVSNAPHVMTSSTVEVSKSTFLTSDMISAHPFTNLTTL--PSATMSTILTR 2070
            S  +GSP  T+S  P   TS  ++   +TF T      HP +  TT   PS   + +   
Sbjct: 2669 S--TGSPRTTLS--PASSTSPGLQGESTTFQT------HPASTHTTPSPPSTATAPVEES 2718

Query: 2071 TIPTPTLGGI-TTGFPTSLPMSINVTDDIVYISTHPEASSRTTITANPRTVSHPSSFSRK 2129
            T    + G   TT FP S   S +     ++ S+ P+AS  T  +A+  T     S + +
Sbjct: 2719 TTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSS-PDASGTTPSSAHSTTSGRGESTTSR 2777

Query: 2130 TMSPSTTDHTLSVGAMPLPSSTITSSWNRIPTASSPSTLIIPKPTLDSLLNIMTTTSTVP 2189
             +SP +T+ T       LP ST T      P  S  ST     P         + T+T+ 
Sbjct: 2778 -ISPGSTEITT------LPGSTTT------PGLSEASTTFYSSPR--------SPTTTLS 2816

Query: 2190 GASFPLISTGVTYPFTATVSSPISSFFETTWLDSTPSFLSTEASTSPTATKSTVSFYNVE 2249
             AS  + S GV    T + S P           ST S +S  ++T+P  ++ + + Y+  
Sbjct: 2817 PAS--MTSLGVGEESTTSRSQP----------GSTHSTVSPASTTTPGLSEESTTVYSSS 2864

Query: 2250 MSFSVFVEEPRIPITSVINE 2269
               +     PR   TSV  E
Sbjct: 2865 PGSTETTVFPRSTTTSVRGE 2884



 Score =  216 bits (550), Expect = 3e-55
 Identities = 536/2225 (24%), Positives = 835/2225 (37%), Gaps = 330/2225 (14%)

Query: 220  PTVDRTLRCFVPENMTIQEKSTTVSQQIDMTTPSQITGVKPQN-TAHSSTLLSQSIPIFA 278
            P+  R+    + E  T    S   +Q +     S  +G   ++ T+HSST  + S P   
Sbjct: 1898 PSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPST 1957

Query: 279  TDY-----------------TTISYSNTTSPPLETMTAQKILKTLVDETATFAVDVLSTS 321
            T                   T    S+TTS   E  TA    +   D T T  +   ST+
Sbjct: 1958 TSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQ---DATGTIVLPARSTT 2014

Query: 322  SAISLPTQSISIDNTTNSMKKTKSPSSESTKTTKMVEAMATEIFQPPTPSNFLSTSRFTK 381
            S   L  +S +   ++ SM+ T  P S  T T  + E   T    P +P+  LS +  T 
Sbjct: 2015 SV--LLGESTTSPISSGSMETTALPGS--TTTPGLSEKSTTFHSSPRSPATTLSPASTTS 2070

Query: 382  NSVVSTTSAIKSQSAVTKTTSLFSTIESTSMS---TTPCLKQKSTNTGALPISTAGQ-EF 437
            + V   ++   S+   T TT+   +  +  +S   TT      ST+T  LP ST      
Sbjct: 2071 SGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPS 2130

Query: 438  IESTAAGTVPWFTVEKTSPASTHVGTASSFPPEPVLISTAAPVDSVFPRNQTAFPLATTD 497
             EST + + P  T    SP ST   TA SF  E     +     S    + T FP +TT 
Sbjct: 2131 QESTTSHSSPGSTDTALSPGST---TALSFGQESTTFHS-----SPGSTHTTLFPDSTTS 2182

Query: 498  MKI---AFTVHSLTLPTRLI-------------------------ETTPAP---RTAETE 526
              I   +  VHS T   R                            TTP+P    TA  E
Sbjct: 2183 SGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVE 2242

Query: 527  LTSTNFQDVSLPRVEDAMSTSMSKETSSKTFSFLTSFSFTGTESVQTVIDAEATRTALTP 586
             ++T  +           ++S +   S K+  F +S   +GT              + T 
Sbjct: 2243 ESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTS 2302

Query: 587  EITLASTVAETMLSSTITGRVYTQNTP----------TADGHLLTLMSTRSASTSKAPES 636
             I+  ST   T+  ST T  +   +T           T     +T +     ST+   + 
Sbjct: 2303 RISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQP 2362

Query: 637  GPTSTTDEAAH-----LFSSNETIWTSRP---DQALLASMNTTTILTFVPNENFTSAFHE 688
            G T +T   A      L   + T+++S P   +  +     TT++    P    +     
Sbjct: 2363 GSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPAST 2422

Query: 689  NTTYTEYLSATTNITPLKASPEGKGTTANDATTARYTTAVSKLTSPWFANFSIVSGTTSI 748
            +TT     S T+ +T    +  G   +      A  TTA     S  F + S   G+T  
Sbjct: 2423 HTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSS---GSTGT 2479

Query: 749  TNMPEFKLTTLLL-KTIPMSTKPAN-ELPLTPRETVVPSVDIISTLACIQPNFSTEESAS 806
            T  P    T+ L+ ++ P    P++ E    P     PS+   ST     P  S + + S
Sbjct: 2480 TLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPR-SPDATLS 2538

Query: 807  ETTQTEINGAIVFGGTTTPVPKSATTQRLNATVTRKEATSHYLMRKSTIAAVAEVSPFST 866
              T T  +G      T+   P S  T     T      T+  L R ST +  +  S  +T
Sbjct: 2539 PATTTS-SGVSEESSTSHSQPGSTHT-----TAFPDSTTTPGLSRHSTTSHSSPGSTDTT 2592

Query: 867  MLEVTDESAQRVTASVTVSSFPDIEKLSTPLDNKTATTEVRESWLLTKLVKTTPRSSYNE 926
            +L  +  ++     S T  S P     +    + TA +  +ES        +T  + + +
Sbjct: 2593 LLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPD 2652

Query: 927  MTEMFNFNH--TYVAHWTSETSEGISAGSPTS----GSTHIFGEPLGASTTRISETSFST 980
             T         T V   T      +S  S TS    G +  F     ++ T  S  S +T
Sbjct: 2653 STTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTAT 2712

Query: 981  TPTDRTATSLSDGILPPQPTAAHSSATPVPVTHMFSLPVNGSSVVAEETEVTMSEPSTLA 1040
             P + + T       P      H  A+     H     +  SS  A  T  + +  +T  
Sbjct: 2713 APVEESTTYHRS---PGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSG 2769

Query: 1041 RAFSTSVLSDVSNLSSTTMTTALVPPLDQTASTTIVIVPTHGDLIRTTSEATVISVRK-- 1098
            R  ST+      +   TT+  +   P    ASTT    P       + +  T + V +  
Sbjct: 2770 RGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEES 2829

Query: 1099 -TSMAVPSLTETPFHSLRLSTPVTAKAETTLFSTSVD----TVTP-STHTLVCSKPPPDN 1152
             TS + P  T +       +TP  ++  TT++S+S      TV P ST T V  + P   
Sbjct: 2830 TTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTF 2889

Query: 1153 IPPASSTHVI-----STTS-----------TPEATQP-------ISQVEETSTYALSFPY 1189
                +STH       STTS           +P +TQ         + + E ST   +FP 
Sbjct: 2890 HSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEEST---TFPS 2946

Query: 1190 TFSGGGVVASLATGTTETSVVDETTPSHISANKLTTSVNSHISSSATYRVHTPVSIQLVT 1249
            +    G   S A  TT + +V E+TPS +S +   T+    +  S T    TP S+   +
Sbjct: 2947 SSGSTGTTLSPARSTT-SGLVGESTPSRLSPSSTETTT---LPGSPT----TP-SLSEKS 2997

Query: 1250 STSVLSSDKDQMTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISS 1309
            +T   S      T+S   T  +  V+E S + +S    +  T   + T T        +S
Sbjct: 2998 TTFYTSPRSPDATLSPATTTSS-GVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTAS 3056

Query: 1310 HQTHSPSEIPL--GTPSDGNLA-------SSPTSGSTQITP------------TLTSSNT 1348
            H +   +E  L  G+ +  +L        SSP    T + P            T T S+T
Sbjct: 3057 HSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSST 3116

Query: 1349 VGVHI---PEMSTSLG--KTALPSQALTITTFLCPEKESTSALPAYTPRTVEMIVNSTYV 1403
              +H    P  STS G  + +   Q+   ++   P    T+A P     T     +ST  
Sbjct: 3117 GSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPT 3176

Query: 1404 THSVSYGQDTSFVDTTTSSSTRISNPMDINT----TFSHLHSLRTQPEVTSVASFISEST 1459
            TH   +   ++ +  +  S+T  S+P    T    T S    L  +P  + ++S    ST
Sbjct: 3177 TH---FSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISS---GST 3230

Query: 1460 QTFPESLSLSTAGLYNDGFTVLSDRITTAFSVPNVP--TMLPRESSMATSTPIYQMSSLP 1517
            +T     S +TAGL        S++ TT +S P  P  T+ P  ++ +  +     S   
Sbjct: 3231 ETTALPGSTTTAGL--------SEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSR 3282

Query: 1518 VNVTAFTSKKVSDTPPIVITKSSKT-MHPGCLK---SPCTATSGPMSEMSSIPVNNSAFT 1573
               T  T+   S T P V  +S+ +   PG      SP + T+  +   S+   +    T
Sbjct: 3283 PGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGST 3342

Query: 1574 PATVSSDTSTRVGLF--STLLSSVT--PRTTMTMQTSTL---------------DVTPVI 1614
              T+  D +T  GL   ST + S T  P TT++   ST                D TP  
Sbjct: 3343 ETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTP-- 3400

Query: 1615 YAGATSKNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTLPFVK---TVPTTIMAGIVTPF 1671
             A  T+ +  V  + T+    +PS  TPTT  S +  TL   +   TV ++ +A   TP 
Sbjct: 3401 -APPTTTSAFVELSTTSH--GSPSS-TPTTHFSASSTTLGRSEESTTVHSSPVATATTPS 3456

Query: 1672 VGTTAFSPLSSKSTGAISSIPKTTFSPFLSATQQSSQADEATTLGILSGITNRSLSTVNS 1731
               +  S L  +ST   SS   T    F  +   S + +E+TT       T  ++S+  S
Sbjct: 3457 PARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTS---HSSTTHTISSAPS 3513

Query: 1732 GTGVALTDTYSRITVPENMLSPTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCF 1791
             T   + +  S  + P +  +    DS  TS   + S +  S + A+G            
Sbjct: 3514 TTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGT----------I 3563

Query: 1792 SSNTRKMTSLLEKTSLTNYATSLNTPVSYPPWTPSSATLPSL----TSFVYSPHSTEAEI 1847
                R  TS+L   S T+  +S +   +     P S T P L    T+F  SP S    +
Sbjct: 3564 VLPARSTTSVLLGESTTSPISSGSMETTA---LPGSTTTPGLSEKSTTFHSSPRSPATTL 3620

Query: 1848 STPKTSPPPTSQMVEFPVLGTRMTSSNTQPLLMTSWNIPTAEGSQFPISTTINVPTSNEM 1907
            S   T+    S+           T+S+++P         +   + FP STT   P  +  
Sbjct: 3621 SPASTTSSGVSE---------ESTTSHSRP--------GSTHTTAFPDSTT--TPGLSRH 3661

Query: 1908 ETETLHLVPGPLSTFTASQTGLVSKDVMAMSSIPMSGILPNHGLSENPSLSTSLRAITST 1967
             T T H  PG   T             +  +S   SG       S + S ST       +
Sbjct: 3662 ST-TSHSSPGSTDT------------TLLPASTTTSGSSQESTTSHSSSGSTDTALSPGS 3708

Query: 1968 LADVKHTFEKMTTSVTPGTTLPSILSGATSGSVISKSPILTWLLSSLPSGSPPATVSNAP 2027
               +    E  T   +PG+T  ++   +T+ S I ++   T + SS  +GSP  T+S  P
Sbjct: 3709 TTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEAS--TRVHSS--TGSPRTTLS--P 3762

Query: 2028 HVMTSSTVEVSKSTFLTSDMISAHPFTNLTTL--PSATMSTILTRTIPTPTLGGI-TTGF 2084
               TS  ++   + F T      HP +  TT   PS   + +   T    + G   TT F
Sbjct: 3763 ASSTSPGLQGESTAFQT------HPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHF 3816

Query: 2085 PTSLPMSINVTDDIVYISTHPEASSRTTITANPRTVSHPSSFSRKTMSPSTTDHTLSVGA 2144
            P S   S +     ++ S+ P+AS  T  +A+  T     S + + +SP +T+ T     
Sbjct: 3817 PASSTTSGHSEKSTIFHSS-PDASGTTPSSAHSTTSGRGESTTSR-ISPGSTEITT---- 3870

Query: 2145 MPLPSSTITSSWNRIPTASSPSTLIIPKPTLDSLLNIMTTTSTVPGASFPLISTGVTYPF 2204
              LP ST T      P  S  ST     P         + T+T+  AS  + S GV    
Sbjct: 3871 --LPGSTTT------PGLSEASTTFYSSPR--------SPTTTLSPAS--MTSLGVGEES 3912

Query: 2205 TATVSSPISSFFETTWLDSTPSFLSTEASTSPTATKSTVSFYNVEMSFSVFVEEPRIPIT 2264
            T + S P           ST S +S  ++T+P  ++ + + Y+     +     PR   T
Sbjct: 3913 TTSRSQP----------GSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTT 3962

Query: 2265 SVINE 2269
            SV  E
Sbjct: 3963 SVRRE 3967



 Score =  216 bits (550), Expect = 3e-55
 Identities = 507/2154 (23%), Positives = 800/2154 (37%), Gaps = 297/2154 (13%)

Query: 248  DMTTPSQITGVKPQNTAHSSTLLSQSIPIFATDYTTISYSNTTSPPLETMTAQKILKTLV 307
            D TT S I  V+     HSST          +  TT+S +++TSP L+            
Sbjct: 2178 DSTTSSGI--VEASTRVHSST---------GSPRTTLSPASSTSPGLQ------------ 2214

Query: 308  DETATFAVDVLSTSSAISLPT-------QSISIDNTTNSMKKTKSPSSESTK--TTKMVE 358
             E+  F     ST +  S P+       +S +   +  S   T  P+S +T   + K   
Sbjct: 2215 GESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTI 2274

Query: 359  AMATEIFQPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFSTIESTSMSTTPCL 418
              ++      TPS+  ST   T     STTS I   S  T+ T+L         +TTP L
Sbjct: 2275 FHSSPDASGTTPSSAHST---TSGRGESTTSRISPGS--TEITTL------PGSTTTPGL 2323

Query: 419  KQKSTNTGALPIS-TAGQEFIESTAAGTVPWFTVEKTSPASTH--VGTASSFPP----EP 471
             + ST   + P S T        T+ G     T  ++ P STH  V  AS+  P    E 
Sbjct: 2324 SEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEES 2383

Query: 472  VLISTAAPVDS---VFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETTPAPRTAETELT 528
              + +++P  +   VFPR     P  +   +   T HS    T     T    T+     
Sbjct: 2384 TTVYSSSPGSTETTVFPRT----PTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEE 2439

Query: 529  STNFQDVSLPRVEDAMSTSMSKETSSKTFSFLTSFSFTGTESVQTVIDAEATRTALTPEI 588
            ST F            +T  + +   ++ +F +S   TGT    T+  A +T + L  E 
Sbjct: 2440 STAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGT----TLSPARSTTSGLVGES 2495

Query: 589  TLASTVAETMLSSTITGRVYTQNTPTADGHLLTLMSTRSASTSKAPES--GPTSTTDEAA 646
            T +     +  ++T+ G   +  TP+     L+  ST   ++ ++P++   P +TT    
Sbjct: 2496 TPSRLSPSSTETTTLPG---SPTTPS-----LSEKSTTFYTSPRSPDATLSPATTTSSGV 2547

Query: 647  HLFSSNETIWTSRPDQALLASMNTTTILTFVPNENFTSAFHENTTYTEYLSATTNITPLK 706
               SS               S   +T  T  P+   T     ++T +     +T+ T L 
Sbjct: 2548 SEESSTSH------------SQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLP 2595

Query: 707  ASPEGKGTTANDATTARYTTAVSKLTSPWFAN-FSIVSGTTSITNMPEFKLTTLLLKTIP 765
            AS    G +    T+     +     SP      S    +T+  + P    TTL   +  
Sbjct: 2596 ASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTT 2655

Query: 766  MS-----TKPANELPLTPRETVVPSVDIISTLACIQPNFSTEESASETTQTEINGAIVFG 820
             S     +   +    +PR T+ P+      L      F T  +++ TT +  + A    
Sbjct: 2656 SSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTA---- 2711

Query: 821  GTTTPVPKSATTQRL-NATVTRKEATSHYLMRKSTIAAVAEVSPFSTMLEVTDESAQRVT 879
              T PV +S T  R   +T T     S      S  + +   SP ++    T  SA   T
Sbjct: 2712 --TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS--GTTPSSAHSTT 2767

Query: 880  ASVTVSSFPDIEKLSTPLDNKTATTEVRESWLLTKLVKTTPRSSYNEMTEMFNFNHTYVA 939
            +    S+   I   ST +     +T        +    ++PRS    ++           
Sbjct: 2768 SGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSP---------- 2817

Query: 940  HWTSETSEGISAGSPTS----GSTHIFGEPLGASTTRISETS---FSTTPTDRTAT---- 988
               S TS G+   S TS    GSTH    P   +T  +SE S   +S++P     T    
Sbjct: 2818 --ASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPR 2875

Query: 989  SLSDGILPPQPTAAHSSATPVPVTHMFSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVL 1048
            S +  +   +PT  HS       T +F+     S +  E T    S  ST     +T   
Sbjct: 2876 STTTSVRGEEPTTFHSRPASTHTT-LFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTT 2934

Query: 1049 SDVSNLSST--TMTTALVPPLDQTASTTIVIV--PTHGDLIRTTSEATVISVRKTSMAVP 1104
            +D+   S+T  + + +    L    STT  +V   T   L  +++E T +    T+ ++ 
Sbjct: 2935 ADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLS 2994

Query: 1105 SLTETPFHSLRLSTPVTAKAETTLFSTSVDTVTP-----STHTLVCSKPPPDNIPPASST 1159
              + T + S R      + A TT    S ++ T      STHT         +      T
Sbjct: 2995 EKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPT 3054

Query: 1160 HVISTTSTPEATQPISQVEETSTYALSFPYTFSGGGVVASLATGTTETS-VVDETTPSHI 1218
               S+  + EAT        +S    S  +  S G    +L    T TS +V+ +TP+H 
Sbjct: 3055 ASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHS 3114

Query: 1219 SANKLTTSVNSHISSSATYRVHT----------------------PVSIQLVTSTSVLSS 1256
            S   L T++    S+SA  +  +                      PV +     +   S+
Sbjct: 3115 STGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSST 3174

Query: 1257 DKDQMTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSPS 1316
                 + S     R+ E T +  S  +  +    T S      G P T+ ISS  T + +
Sbjct: 3175 PTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTA 3234

Query: 1317 EIPLGTPSDG------NLASSPTSGSTQITPTLTSSNTVGV-----HIPEMSTSL----G 1361
             +P  T + G         SSP S  T ++P  T+S+ V       H    ST      G
Sbjct: 3235 -LPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPG 3293

Query: 1362 KTALPSQALTIT-TFLCPEKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFV--DT 1418
             T +P  +   T +   P    T+  P  T  T   +   +   HS     +T+ +  +T
Sbjct: 3294 STTMPGVSQESTASHSSPGSTDTTLSPGST--TASSLGPESTTFHSGPGSTETTLLPDNT 3351

Query: 1419 TTSSSTRISNPMDINT-----TFSHLHSLRTQPEVTSVASFI-SESTQTFPESLSLSTAG 1472
            T S     S P+  +T     T S   S   Q E T+  S+  S+ T   P + + +   
Sbjct: 3352 TASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVE 3411

Query: 1473 LYNDGFTVLSDRITTAFSVPNVPTMLPRESSMATSTPIYQMSSLPVNVTAFTSKKVSDTP 1532
            L        S   TT FS  +       ES+   S+P+   ++ P    + TS  V ++ 
Sbjct: 3412 LSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPV-ATATTPSPARSTTSGLVEEST 3470

Query: 1533 PIVITK-SSKTMH-------PGCLKSPCTATSGPMSEMSSIPVNNSAFTPATVS---SDT 1581
                +  S++TMH        G  +   T+ S     +SS P   SA      S   S  
Sbjct: 3471 TYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPG 3530

Query: 1582 STRVGLFSTLLSSVTPRTTMTMQTSTLDVTPVIYAGATSKNKMVSSAFTTEMIEAPSRIT 1641
            ST    F    ++       T   S+ D T  I   A S   ++    TT  I + S  T
Sbjct: 3531 STATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMET 3590

Query: 1642 PTTFLSPTEPTLPFVKTVPTTIMAGIVTPFV----GTTAFSPLSSKSTGAISSIPKTTFS 1697
                  P   T P +    TT  +   +P       +T  S +S +ST + S    T  +
Sbjct: 3591 TAL---PGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTT 3647

Query: 1698 PFLSATQQSSQADEATTLGILSGITNRSL---STVNSGTGVALTDTYSRITVPENMLSPT 1754
             F  +T     +  +TT     G T+ +L   ST  SG+    T ++S     +  LSP 
Sbjct: 3648 AFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPG 3707

Query: 1755 HADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLLEKTSLTNYATSL 1814
               +L            T+F S+ G T      T  F  +T     +   T + +   S 
Sbjct: 3708 STTAL------SFGQESTTFHSSPGSTH-----TTLFPDSTTSSGIVEASTRVHSSTGSP 3756

Query: 1815 NTPVSYPPWTPSSATLPSL----TSFVYSPHSTEAEISTPKTSPPPTSQMVEFPVLGTRM 1870
             T +S     P+S+T P L    T+F   P ST    S P T+  P  +           
Sbjct: 3757 RTTLS-----PASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEES---------- 3801

Query: 1871 TSSNTQPLLMTSWNIPTAEGSQFPISTTINVPTSNEMETETL-HLVPGPLSTFTASQ--- 1926
            T+ +  P      + PT   + FP S+T    TS   E  T+ H  P    T  +S    
Sbjct: 3802 TTYHRSP-----GSTPT---THFPASST----TSGHSEKSTIFHSSPDASGTTPSSAHST 3849

Query: 1927 --------TGLVSKDVMAMSSIPMSGILPNHGLSE-NPSLSTSLRAITSTLADVKHTF-- 1975
                    T  +S     ++++P S   P  GLSE + +  +S R+ T+TL+    T   
Sbjct: 3850 TSGRGESTTSRISPGSTEITTLPGSTTTP--GLSEASTTFYSSPRSPTTTLSPASMTSLG 3907

Query: 1976 ---EKMTTSVTPGTTLPSILSGATSGSVISKSPILTWLLSSLPSGSPPATVSNAPHVMTS 2032
               E  T+   PG+T  ++   +T+   +S+    T + SS P GS   TV   P   T+
Sbjct: 3908 VGEESTTSRSQPGSTHSTVSPASTTTPGLSEES--TTVYSSSP-GSTETTVF--PRSTTT 3962

Query: 2033 STVEVSKSTF-----------LTSDMISAHPFTNLTTLPSATMSTI--LTRTIPTPTLGG 2079
            S      +TF            T D  ++      T  P +  ST   L  T+ T  LG 
Sbjct: 3963 SVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGE 4022

Query: 2080 ITTGFPTS-------LPMSINVTDDIVYIST----HPEASSRTTITANPRTVSHPSSFSR 2128
             +T FP+S       L  + + T  +V  ST     P ++  TT+  +P T S     + 
Sbjct: 4023 ESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTT 4082

Query: 2129 KTMSPSTTDHTLSVGAMPLPSSTITSSWNRIPTASSPSTLIIPKPTLDSLLNIMTTTSTV 2188
               SP + D TLS         +  SS +     S+ +T      T   L    TT+ + 
Sbjct: 4083 FYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSS 4142

Query: 2189 PGASFPLISTGVTYPFTATVSSPISSFFETTWLDSTPSFLSTEASTSPTATKST 2242
             G++   +S G T   TA+     S+ F ++  D+  + L  +  TS     ST
Sbjct: 4143 QGSTEATLSPGST---TASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEAST 4193



 Score =  209 bits (533), Expect = 3e-53
 Identities = 518/2149 (24%), Positives = 824/2149 (38%), Gaps = 364/2149 (16%)

Query: 308  DETATFAVDVLSTSSAISLPTQSISIDNTTNSMKKTKSP-----------SSESTKTTKM 356
            +E+ATF      T S+    T +++  +  +S+  T++            S ES  +   
Sbjct: 527  EESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSS 586

Query: 357  VEAMATEIFQP----------PTPSNFLSTSRFTKNSVVSTTSAIKSQSAVT-------- 398
             +AMAT +              TPS   S S  T     STT    S+ + T        
Sbjct: 587  PDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSP 646

Query: 399  KTTSLFSTIESTSMS---TTPCLKQKSTNTGALPISTAGQEFI-ESTAAGTVPWFTVEKT 454
             TT L +++ S+ +S   TT   +  ST+T A P ST       ESTA+ + P  T    
Sbjct: 647  DTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTL 706

Query: 455  SPASTHVGTASSFPPEPVLIST--AAPVDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTR 512
            SP ST   TASS  PE     +   +   ++ P N TA  L    M     VHS    TR
Sbjct: 707  SPGST---TASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMP----VHS---STR 756

Query: 513  LIETTPAPRTAETEL-TSTNFQDVSLPRVEDAMSTSMSKETSSKTFSFLTSFSFTGTESV 571
               TT +P  + T    ST F   S P  +D   T  +  T++  F   ++ S     S+
Sbjct: 757  SPHTTLSPAGSTTRQGESTTFH--SWPSSKD---TRPAPPTTTSAFVEPSTTSHGSPSSI 811

Query: 572  QTV-IDAEATRTALTPEITLASTVAETMLSSTITGRVYTQNTPTADGHLLTLMSTRSAST 630
             T  I A +T + L  E    ST   +   ST T      +T +  G   T   + +  T
Sbjct: 812  PTTHISARSTTSGLVEE----STTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHT 867

Query: 631  -SKAPESGPTSTTDEAAHLFSSNETIWTSRPDQA----------------------LLAS 667
             S AP +      +  ++  S   T  T  PD +                      +L +
Sbjct: 868  ISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPA 927

Query: 668  MNTTTILTFVPNENFTSAFHENTTYTEYLSATTNI-------TPLKASPEGKGTTANDAT 720
             +TT++L     E+ TS     +  T  L  +T         T   +SP    TT + A+
Sbjct: 928  RSTTSVLL---GESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPAS 984

Query: 721  TARYTTAVSKLTSPWFANFSIVSGTTSITNMPEFKLTTLLLK--TIPMSTKPANELPLTP 778
            T     +    TS          G+T  T  P+   T  L +  T   S+  + +  L P
Sbjct: 985  TTSSGVSEESTTS------RSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLP 1038

Query: 779  RETVVPSVDIISTLACIQPNFSTEESASETTQTEING----AIVFGGTTTPVPKSATTQR 834
              T        ST         T  S+S +T T ++     A+ FG  +T    +  +  
Sbjct: 1039 ASTTTSGPSQEST---------TSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGST- 1088

Query: 835  LNATVTRKEATSHYLMRKSTIAAVAEVSPFSTMLEVTDESAQRVTASVTVSSFPDIEKLS 894
             + T+     TS  ++  ST    +  SP +T+   +  S      S    + P     +
Sbjct: 1089 -HTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHP-ASTHT 1146

Query: 895  TPLDNKTATTEVRESWLLTKLVKTTPRSSYNEMTEMFNFNHTYVAHWTSETSEGI---SA 951
            TP    TAT  V ES    +   +TP + +   +     +       +S  + G    SA
Sbjct: 1147 TPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSA 1206

Query: 952  GSPTSGSTHIFGEPLGASTTRIS--ETSFSTTPTDRTATSLSDGILPPQPTAAHSSATPV 1009
             S TSG     GE   ++T+RIS   T  +T P   T   LS+                 
Sbjct: 1207 HSTTSGR----GE---STTSRISPGSTEITTLPGSTTTPGLSEAS--------------- 1244

Query: 1010 PVTHMFSLPVNGSSVV--AEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVPPL 1067
              T  +S P + ++ +  A  T + + E ST +R+   S  S VS  S+TT      P L
Sbjct: 1245 --TTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTT------PGL 1296

Query: 1068 DQTASTTIVIVPTHGDLIRTTSEATVISVRKTSMAVPSLTETPFHSLRLSTPVTAKAE-- 1125
             + ++T            R ++E TV     T+ +V     T FHS   ST  T   E  
Sbjct: 1297 SEESTTVY-------SSSRGSTETTVFP-HSTTTSVHGEEPTTFHSRPASTHTTLFTEDS 1348

Query: 1126 TTLFSTSVDTVTPSTHTLVCSKPPPDNIPPASSTHVISTTSTPEATQPISQVEETSTYAL 1185
            TT   T   T  P +             P ++ T + +T +T +        EE++T   
Sbjct: 1349 TTSGLTEESTAFPGS-------------PASTQTGLPATLTTADLG------EESTT--- 1386

Query: 1186 SFPYTFSGGGVVASLATGTTETSVVDETTPSHISANKLTTSVNSHISSSATYRVHTPVSI 1245
             FP +    G   S A  TT + +V E+TPS +S +   T+    +  S T    TP S+
Sbjct: 1387 -FPSSSGSTGTKLSPARSTT-SGLVGESTPSRLSPSSTETTT---LPGSPT----TP-SL 1436

Query: 1246 QLVTSTSVLSSDKDQMTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETT 1305
               ++T   S      T+S   T      T    S+ S  S+S+  P    T T FP++T
Sbjct: 1437 SEKSTTFYTSPRSPDATLSPATT------TSSGVSEESSTSHSQ--PGSTHT-TAFPDST 1487

Query: 1306 KISSHQTHSPSEIPLGTPSDGNLASSPTSGSTQIT--PTLTSSNTVGVHIPEMSTSLGKT 1363
              +S  +  P+             S  + GST+ T  P  T+++++G       +S G T
Sbjct: 1488 T-TSDLSQEPT------------TSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDT 1534

Query: 1364 A---LPSQALT--ITTFLCPEKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDT 1418
                LP   +T  +     P   ST +L  +T  T     ++     S ++    S  DT
Sbjct: 1535 ETTLLPDDTITSGLVEASTPTHSSTGSL--HTTLTPASSTSAGLQEESTTFQSWPSSSDT 1592

Query: 1419 TTSSSTRISNPMDINTTFSHLHSLRTQPEVTSVASFISESTQTFPESLSLSTAGLYNDGF 1478
            T S     + P++++TT+       ++P  T    F + ST          T G      
Sbjct: 1593 TPSPPGTTAAPVEVSTTY------HSRPSSTPTTHFSASST----------TLGR----- 1631

Query: 1479 TVLSDRITTAFSVPNVPTMLPRESSMATSTPIYQMSSLPVNV--TAFTSKKVSDTPPIVI 1536
               S+  TT  S P         +  ATS  + + ++ P++   T  T+   S T   + 
Sbjct: 1632 ---SEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLS 1688

Query: 1537 TKS----SKTMHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPATVSSDTSTRVGLF---- 1588
             KS    S    P    SP + TS  +SE S+   +    T  T    ++T  G+     
Sbjct: 1689 EKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQEST 1748

Query: 1589 ----------STLLSSVTPRTTMTMQTSTLDVTPVIYAGATSKNKMVSSAFTTEMIEAPS 1638
                      +TL    T  +++  +++T   +P    G+T    +  +   + ++EA +
Sbjct: 1749 ASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSP----GSTETTLLPDNTTASGLLEAST 1804

Query: 1639 RI-----TPTTFLSPTEPTLPFVKTVPTTIMAG------IVTPFVGTTAFSPLSSKSTGA 1687
             +     +P T LSP   T    ++  TT  +       +  P   T+AF  LS+ S G+
Sbjct: 1805 PVHSSTGSPHTTLSPAGSTTRQGES--TTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGS 1862

Query: 1688 ISSIPKTTFSPFLSATQQSSQADEATTLGILSGITNRSLSTVNSGTGVALTDTYSRITVP 1747
             SS P T FS   +   +S ++    +  + +  T     +  SG     T  +S     
Sbjct: 1863 PSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGST 1922

Query: 1748 ENMLSPTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLLEKTSL 1807
            + M  P  + +   S   + S S T+   +S P     +TT+          S    T+ 
Sbjct: 1923 QTMHFPESSTASGRSEESRTSHSSTTHTISSPP-----STTSALVEEPTSYHSSPGSTAT 1977

Query: 1808 TNYATSLNTPVSYPPWTPSSATLPSLTSFVYSPHSTEAEISTPKTSPPPTSQMVEFPVLG 1867
            T++  S  T       T S ++  +  + V    ST + +    T+ P +S  +E   L 
Sbjct: 1978 THFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALP 2037

Query: 1868 TRMTSSNTQPLLMTSWNIPTAEGSQFPISTTINVPTSNEMETETLHLVPGPLSTFT---A 1924
               T+        T  + P +  +    ++T +   S   E+ T H  PG   T     +
Sbjct: 2038 GSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSE--ESTTSHSRPGSTHTTAFPDS 2095

Query: 1925 SQTGLVSKDVMAMSSIPMS---GILP----NHGLSENPSLSTSLRAITSTLADVKHTF-- 1975
            + T  +S+      S P S    +LP      G S+  + S S    T T      T   
Sbjct: 2096 TTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTAL 2155

Query: 1976 ----EKMTTSVTPGTTLPSILSGATSGSVISKSPILTWLLSSLPSGSPPATVSNAPHVMT 2031
                E  T   +PG+T  ++   +T+ S I ++   T + SS  +GSP  T+S  P   T
Sbjct: 2156 SFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEAS--TRVHSS--TGSPRTTLS--PASST 2209

Query: 2032 SSTVEVSKSTFLTSDMISAHPFTNLTT--LPSATMSTILTRTIPTPTLGGI-TTGFPTSL 2088
            S  ++   + F T      HP +  TT   PS   + +   T    + G   TT FP S 
Sbjct: 2210 SPGLQGESTAFQT------HPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASS 2263

Query: 2089 PMSINVTDDIVYISTHPEASSRTTITANPRTVSHPSSFSRKTMSPSTTDHTLSVGAMPLP 2148
              S +     ++ S+ P+AS  T  +A+  T     S + + +SP +T+ T       LP
Sbjct: 2264 TTSGHSEKSTIFHSS-PDASGTTPSSAHSTTSGRGESTTSR-ISPGSTEIT------TLP 2315

Query: 2149 SSTITSSWNRIPTASSPSTLIIPKPTLDSLLNIMTTTSTVPGASFPLISTGVTYPFTATV 2208
             ST T      P  S  ST     P         + T+T+  AS  + S GV    T + 
Sbjct: 2316 GSTTT------PGLSEASTTFYSSP--------RSPTTTLSPAS--MTSLGVGEESTTSR 2359

Query: 2209 SSPISSFFETTWLDSTPSFLSTEAST----SPTATKSTVSFYNVEMSFSVFVEEPRI--- 2261
            S P S+    +   +T   LS E++T    SP +T++TV  +    + SV  EEP     
Sbjct: 2360 SQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTV--FPRTPTTSVRGEEPTTFHS 2417

Query: 2262 -PITSVINEFTENSLNS-------IFQNSEFSLAT-LETQIKSRDISEE 2301
             P ++    FTE+S  S        F  S  S  T L   + + D+ EE
Sbjct: 2418 RPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEE 2466



 Score =  194 bits (494), Expect = 9e-49
 Identities = 504/2136 (23%), Positives = 792/2136 (37%), Gaps = 333/2136 (15%)

Query: 223  DRTLRCFVPENMTIQEKSTTVSQQ------IDMTTPSQITGVKPQNTAHSSTLLSQSIPI 276
            DRTL      +  + EKSTT   +      I     + + GV  ++TA      S SIP 
Sbjct: 291  DRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTA------SHSIP- 343

Query: 277  FATDYTTISYSNTTSPPLETMTAQKILKTLVDETATFAVDVLSTSSAISLPTQSISIDNT 336
             +TD TT+S   TT              +L  E+ TF       SS     T  +  + T
Sbjct: 344  GSTD-TTLSPGTTTP------------SSLGPESTTFH------SSPGYTKTTRLPDNTT 384

Query: 337  TNSMKKTKSPSSESTKTTKMVEAMATEIFQPPTPSNFLS--TSRFTKNSVVSTTSA-IKS 393
            T+ + +  +P   ST +     + ++       P+ F S  +S+ T  +   TTSA +K 
Sbjct: 385  TSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKL 444

Query: 394  QSAVTKTTSLFSTIESTSMSTTPCLKQKSTNTGALPISTAGQEFIESTAAGTVPWFTVEK 453
             +    + S   T   ++ STT    ++ST   + P++TA           T P      
Sbjct: 445  STTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATA-----------TTP---PPA 490

Query: 454  TSPASTHVGTASSFPPEPVLISTAAPVDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRL 513
             S  S HV  ++++   P    T       FP + T     +   + + T H  T  T+ 
Sbjct: 491  RSATSGHVEESTAYHRSPGSTQTMH-----FPESST----TSGHSEESATFHGSTTHTKS 541

Query: 514  IETTPAPRTAETELTSTNFQDVSLPRVEDAMSTSMSKETSSKTFSFLTSFSFTGTESVQT 573
               +     A T   S +          D+ + S   E S  + S       +      T
Sbjct: 542  STPSTTAALAHTSYHS-SLGSTETTHFRDSSTISGRSEESKASHS-------SPDAMATT 593

Query: 574  VIDAEATRTALTPEITLASTVAETMLSSTITGRVYTQNTPTADGHLLTLMSTRSASTSKA 633
            V+ A +T + L  + T +   + +M ++ + G   T     ++       S RS  T+  
Sbjct: 594  VLPAGSTPSVLVGDSTPSPISSGSMETTALPGS--TTKPGLSEKSTTFYSSPRSPDTTHL 651

Query: 634  PESGPTSTTDEAAHLFSSNETIWTSRPDQALLASMNTTTILTFVPNENFTSAFHENTTYT 693
            P S  +S   E +    S                          P    T+AF  +TT  
Sbjct: 652  PASMTSSGVSEESTTSHSR-------------------------PGSTHTTAFPGSTTMP 686

Query: 694  EYLSATTNITPLKASPEGKGTTANDATTARYTTAVSKLTSPWFANFSIVSGTTSITNMPE 753
                 +T      AS    G T  D T +  +T  S L  P +  F    G+T  T +P+
Sbjct: 687  GLSQEST------ASHSSPGPT--DTTLSPGSTTASSL-GPEYTTFHSRPGSTETTLLPD 737

Query: 754  FKLTTLLLKTIPMSTKPANELPLTPRETVVPSVDII-----STLACIQPNFSTEESASET 808
                + LL+    ++ P +    +P  T+ P+         +T      +  T  +   T
Sbjct: 738  NTTASGLLE----ASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTT 793

Query: 809  TQTEINGAIVFGGTTTPVPKSATTQRLNATVTRKEATSHYLMRKSTIAAVAEVSPFSTML 868
            T   +  +    G+ + +P +  + R   +   +E+T+++    ST       S  +T  
Sbjct: 794  TSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESD-TTSG 852

Query: 869  EVTDESAQRVTASVTVSSFPDIEKLSTPLDNKTATTEVRESWLLTKLVKTTPRSSYNEMT 928
               + +    + + T+SS P            T +  V E         +T  + + + +
Sbjct: 853  RGEESTTSHSSTTHTISSAP-----------STTSALVEEPTSYHSSPGSTATTHFPDSS 901

Query: 929  EMFNFNHTYVAHWTSETSEGISAGSPTSGSTHIFGEPLGASTTRISETSFSTT--PTDRT 986
                 +    A  +S+ + G       S ++ + GE   ++T+ IS  S  TT  P   T
Sbjct: 902  TTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGE---STTSPISSGSMETTALPGSTT 958

Query: 987  ATSLSDGILPPQPTAAHSSATPVPVTHMFSLPVNGSSVVAEETEVTMSEP-STLARAFST 1045
               LS+     + T  HSS      T   S     SS V+EE+  + S P ST   AF  
Sbjct: 959  TPGLSE-----RSTTFHSSPRSPATT--LSPASTTSSGVSEESTTSRSRPGSTHTTAFPD 1011

Query: 1046 SVL-------SDVSNLSSTTMTTALVPPLDQTASTTIVIVPTHGDLIRTTSEATVISVRK 1098
            S         S  S+ S  +  T L+P    T+  +     +H     + S  T +S   
Sbjct: 1012 STTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSS---SGSTDTALSPGS 1068

Query: 1099 TSMAVPSLTETPFHSLRLSTPVTAKAETTLFSTSVDTVTPSTHTLVCSKPPPDNIPPASS 1158
            T+        T FHS   ST  T   ++T   TS   V  ST     +  P   + PASS
Sbjct: 1069 TTALSFGQESTTFHSNPGSTHTTLFPDST---TSSGIVEASTRVHSSTGSPRTTLSPASS 1125

Query: 1159 -------------THVISTTSTPE----ATQPISQVEETSTYALSFPYTFSGGGVVASLA 1201
                         TH  ST +TP     AT P   VEE++TY  S   T +     +S  
Sbjct: 1126 TSPGLQGESTAFQTHPASTHTTPSPPSTATAP---VEESTTYHRSPGSTPTTHFPASSTT 1182

Query: 1202 TGTTETSVVDETTPSHISANKLTT-SVNSHISSSATYRVHTPVSIQLVT-STSVLSSDKD 1259
            +G +E S +  ++P        +  S  S    S T R+ +P S ++ T   S  +    
Sbjct: 1183 SGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRI-SPGSTEITTLPGSTTTPGLS 1241

Query: 1260 QMTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSP-SEI 1318
            + + +   +PR+   T +SP+  +    S G      T    P +T    H T SP S  
Sbjct: 1242 EASTTFYSSPRS-PTTTLSPASMT----SLGVGEESTTSRSQPGST----HSTVSPASTT 1292

Query: 1319 PLGTPSDGNLASSPTSGSTQITPTLTSSNTVGVHIPEMSTSLGKTALPSQAL-TITTFLC 1377
              G   +     S + GST+ T     S T  VH  E +T   + A     L T  +   
Sbjct: 1293 TPGLSEESTTVYSSSRGSTE-TTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTS 1351

Query: 1378 PEKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINTTFS 1437
               E ++A P  +P + +  + +T  T  +   + T+F  ++ S+ T++S          
Sbjct: 1352 GLTEESTAFPG-SPASTQTGLPATLTTADLG-EESTTFPSSSGSTGTKLS---------- 1399

Query: 1438 HLHSLRTQPEVTSVASFISESTQTFPESLSLSTAGLYNDGFT-VLSDRITTAFSVPNVP- 1495
                    P  ++ +  + EST +     S  T  L     T  LS++ TT ++ P  P 
Sbjct: 1400 --------PARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPD 1451

Query: 1496 -TMLPRESSMATSTPIYQMSSL------PVNVTAF-TSKKVSDTPPIVITKSSKTMHPGC 1547
             T+ P   +  TS+ + + SS         + TAF  S   SD      T  S       
Sbjct: 1452 ATLSP---ATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEA 1508

Query: 1548 LKSPCTATSGPMSEMSSIPVNNSAFTPATVSSDTSTRVGLFS----TLLSSVTPRTTMTM 1603
              SP + T+  + + S+   ++   T  T+  D +   GL      T  S+ +  TT+T 
Sbjct: 1509 TLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTP 1568

Query: 1604 QTSTLDVTPVIYAGATSKNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTLPFVKTVPTTI 1663
             +ST   +  +   +T+     SS+ TT     PS   P T  +P E +  +     +T 
Sbjct: 1569 ASST---SAGLQEESTTFQSWPSSSDTT-----PS--PPGTTAAPVEVSTTYHSRPSST- 1617

Query: 1664 MAGIVTPFVGTTAFSPLSSKSTGAISSIPKTTFSPFLSATQQSSQADEATTLGILSGITN 1723
                 T F  ++     S +ST   SS   T  + F + +  S    E TT  I SG T 
Sbjct: 1618 ---PTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTE 1674

Query: 1724 RSL---STVNSGTGVALTDTYSRITVPENMLSPTHADSLHTSFNIQVSPSLTSFKSASGP 1780
             +    ST  +G     T  YS    P+  LSP    S           S  S +S +  
Sbjct: 1675 TTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTS-----------SGVSEESTTSH 1723

Query: 1781 TKNVKTTTNCFSSNTRKMTSLLEKTSLTNYATSLNTPVSYPPWTPSSATLPSLTSFVYSP 1840
            ++   T T  F  +T       E T+  +   S +T +S P  T +S+  P  T+F  SP
Sbjct: 1724 SRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLS-PGSTTASSLGPESTTFHSSP 1782

Query: 1841 HSTEA-------------EISTPKTSPPPTSQMVEFPVLGTRMTSSNTQPLLMTSWNI-- 1885
             STE              E STP  S   +      P   T     +T      SW    
Sbjct: 1783 GSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGEST---TFQSWPSSK 1839

Query: 1886 ------PTAEGSQFPISTTINVPTSNEMETETLHLVPGPLSTFTASQTGLVSKDVMAMSS 1939
                  PT   +   +STT +   S+   T T H      +   + ++  V    +A ++
Sbjct: 1840 DTMPAPPTTTSAFVELSTTSHGSPSS---TPTTHFSASSTTLGRSEESTTVHSSPVATAT 1896

Query: 1940 IPMSGILPNHGLSENPSLSTSLRAITSTLADVKHTFEKMTTSVTPGTTLPSILSGATSGS 1999
             P        GL E  +   S    T T+    H  E  T S   G +  S  S +++  
Sbjct: 1897 TPSPARSTTSGLVEESTAYHSSPGSTQTM----HFPESSTAS---GRSEESRTSHSSTTH 1949

Query: 2000 VISKSPILTWLLSSLPS---GSPPATVSNAPHVMTSSTVEVSKSTFLTSDMISAHPFTNL 2056
             IS  P  T  L   P+    SP +T +   H   SST          S   S+   T  
Sbjct: 1950 TISSPPSTTSALVEEPTSYHSSPGSTATT--HFPDSSTTSGRSEESTASH--SSQDATGT 2005

Query: 2057 TTLPS-ATMSTILTRTIPTPTLGGI--TTGFPTSLPMSINVTDDIVYISTHPEASSR-TT 2112
              LP+ +T S +L  +  +P   G   TT  P S              +T P  S + TT
Sbjct: 2006 IVLPARSTTSVLLGESTTSPISSGSMETTALPGS--------------TTTPGLSEKSTT 2051

Query: 2113 ITANPR----TVSHPSSFSRKTMSPSTTDHTL--SVGAMPLPSSTITSSWNRIPTAS--- 2163
              ++PR    T+S  S+ S      STT H+   S      P ST T   +R  T S   
Sbjct: 2052 FHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSS 2111

Query: 2164 --SPSTLIIPKPTLDSLLNIMTTTS-TVPGASFPLISTGVTYPF-----TATVSSPISSF 2215
              S  T ++P  T  S  +  +TTS + PG++   +S G T        + T  S   S 
Sbjct: 2112 PGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGST 2171

Query: 2216 FETTWLDSTPSFLSTEAST-------SPTATKSTVS 2244
              T + DST S    EAST       SP  T S  S
Sbjct: 2172 HTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPAS 2207



 Score =  165 bits (417), Expect = 7e-40
 Identities = 416/1732 (24%), Positives = 661/1732 (38%), Gaps = 245/1732 (14%)

Query: 232  ENMTIQEKSTTVSQQIDMTTPSQITGVKPQNTAHSSTLLSQSIPIFATDYTTISYSNTTS 291
            E  T    STT +     +T S +  V+   + HSS          +T  T    S+TTS
Sbjct: 3495 EESTTSHSSTTHTISSAPSTTSAL--VEEPTSYHSSP--------GSTATTHFPDSSTTS 3544

Query: 292  PPLETMTAQKILKTLVDETATFAVDVLSTSSAISLPTQSISIDNTTNSMKKTKSPSSEST 351
               E  TA    +   D T T  +   ST+S   L  +S +   ++ SM+ T  P S  T
Sbjct: 3545 GRSEESTASHSSQ---DATGTIVLPARSTTSV--LLGESTTSPISSGSMETTALPGS--T 3597

Query: 352  KTTKMVEAMATEIFQPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFSTIESTS 411
             T  + E   T    P +P+  LS +  T + V   ++   S+   T TT+   +  +  
Sbjct: 3598 TTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPG 3657

Query: 412  MS---TTPCLKQKSTNTGALPISTAGQ-EFIESTAAGTVPWFTVEKTSPASTHVGTASSF 467
            +S   TT      ST+T  LP ST       EST + +    T    SP ST   TA SF
Sbjct: 3658 LSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGST---TALSF 3714

Query: 468  PPEPVLISTAAPVDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETTPAPRTAETEL 527
              E     +     S    + T FP +TT   I      +   TR+  +T +PRT     
Sbjct: 3715 GQESTTFHS-----SPGSTHTTLFPDSTTSSGI------VEASTRVHSSTGSPRTT---- 3759

Query: 528  TSTNFQDVSLPRVEDAMSTSMSKETSSKTFSFLTSFSFTGTESVQTVIDAEATRTALTPE 587
                        +  A STS   +  S  F                     +T T  +P 
Sbjct: 3760 ------------LSPASSTSPGLQGESTAFQ----------------THPASTHTTPSPP 3791

Query: 588  ITLASTVAETMLSSTITGRVYTQNTP---TADGHLLTLMSTRSASTSKAPESGPTSTTDE 644
             T  + V E+       G   T + P   T  GH     S +S     +P++  + TT  
Sbjct: 3792 STATAPVEESTTYHRSPGSTPTTHFPASSTTSGH-----SEKSTIFHSSPDA--SGTTPS 3844

Query: 645  AAHLFSSNETIWTSRPDQALLASMNTTTILTFVPNENFTSAFHENTT--YTEYLSATTNI 702
            +AH  +S       R +         +T +T +P    T    E +T  Y+   S TT +
Sbjct: 3845 SAHSTTSG------RGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTL 3898

Query: 703  TPLKASPEGKG----TTANDATTARYTTAVSKLTSPWFAN-----FSIVSGTTSITNMPE 753
            +P   +  G G    T+ +   +   T + +  T+P  +      +S   G+T  T  P 
Sbjct: 3899 SPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPR 3958

Query: 754  FKLTTL------LLKTIPMST------KPANELPLTPRETVVPS--------VDIISTLA 793
               T++         + P ST      + +    LT   T  P         +    T A
Sbjct: 3959 STTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTA 4018

Query: 794  CIQPNFSTEESASETTQTEINGAIVFGGTTTPVPKSATTQRLNATVTRKEA-----TSHY 848
             +    +T  S+S +T T+++ A     TT+ +   +T  RL+ + T         T+  
Sbjct: 4019 DLGEESTTFPSSSGSTGTKLSPA---RSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPS 4075

Query: 849  LMRKSTIAAVAEVSPFSTMLEVTDESAQRVTASVT---------VSSFPDIEKLSTPLDN 899
            L  KST    +  SP +T+   T  S+     S T          ++FPD    S     
Sbjct: 4076 LSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQE 4135

Query: 900  KTATTEVRESWLLTKLVKTTPRSSYNEMTEMFNFN----HTYVAHWTSETSEGISAGSPT 955
             T +   + S   T    +T  SS  + +  F+ +     T +    + TS  + A +PT
Sbjct: 4136 PTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPT 4195

Query: 956  ---SGSTHIFGEPLGASTTRISE--TSFSTTPT--DRTATSLSDGILPPQ-PTAAHSSAT 1007
               +GS H    P  +++T + E  T+F + P+  D T +  S   +P +  T  HS  +
Sbjct: 4196 HSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPS 4255

Query: 1008 PVPVTHMFSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDV-------SNLSSTTMT 1060
              P TH FS          E T V  S  +T    F T   + V       S +SS +  
Sbjct: 4256 STPTTH-FSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTE 4314

Query: 1061 TALVPPLDQTA-----STTIVIVPTHGDLI----RTTS-----EATVISVRKTSM---AV 1103
            T  +P    TA     STT    P   D       TTS     E+T    R  SM   A 
Sbjct: 4315 TTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAF 4374

Query: 1104 PSLTETPFHSLRLSTPVTA--KAETTLF--STSVDTVTPSTHTLVCSKPP------PDNI 1153
            PS T  P  S   +   ++    +TTL   ST+  ++ P + T   S         PDN 
Sbjct: 4375 PSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNT 4434

Query: 1154 PPA----SSTHVISTTSTPEATQPISQVEETSTYALSFPYTFSGGGVVASLATGTTETSV 1209
              +    +ST V S+T +P  T  +S    T+    S  +         + A  TT ++ 
Sbjct: 4435 TASGLLEASTPVHSSTGSPHTT--LSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAF 4492

Query: 1210 VDETTPSHISANKLTTSVNSHISSSATY--------RVHT-PVSIQLVTS-----TSVLS 1255
            V+ +T SH S +   T+   H S+S+T          VH+ PV+     S     TS L 
Sbjct: 4493 VELSTTSHGSPSSTPTT---HFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLV 4549

Query: 1256 SDKDQMTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSP 1315
             +      S G T +TM   E + +       +    S   T +  P TT     +  S 
Sbjct: 4550 EESTTYHSSPGST-QTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSY 4608

Query: 1316 SEIPLGTPSDGNLASSPTSG-STQITPTLTSSNTVG-VHIPEMSTS---LGK-TALPSQA 1369
               P  T +     SS TSG S + T + +S +  G + +P  ST+   LG+ T  P  +
Sbjct: 4609 HSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISS 4668

Query: 1370 LTITTFLCPEKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSSTRISNP 1429
             ++ T   P   +T  L   +  T     +ST  TH   +   ++ +  +  S+T  S+P
Sbjct: 4669 GSMETTALPGSTTTPGLSEKST-TFHSSPSSTPTTH---FSASSTTLGRSEESTTVHSSP 4724

Query: 1430 MDINTTFSHLHSLRTQPEVTSVASFISE-STQT--FPESLSLSTAGLYNDGFTVLSDRIT 1486
            +   TT S   S  +     S A   S  STQT  FPES + S  G   +  T  S    
Sbjct: 4725 VATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTAS--GRSEESRTSHSSTTH 4782

Query: 1487 TAFSVPNVPTMLPRESSMATSTPIYQMSSLPVNVTAFTSKKVSDTPPIVITKSSKTMHPG 1546
            T  S P+  + L  E +   S+P   +++     ++ TS +  ++     +  +  + P 
Sbjct: 4783 TISSPPSTTSALVEEPTSYHSSP-GSIATTHFPESSTTSGRSEESTASHSSPDTNGITP- 4840

Query: 1547 CLKSPCTATSGPMSEMSSIPVNNSAFTPATVSSDTSTRVGLFSTLL--SSVTPRTTMT-- 1602
             L +  T TSG ++E ++  ++  +      S+ T+  +   ST+L  SS +P  T++  
Sbjct: 4841 -LPAHFT-TSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPA 4898

Query: 1603 -MQTSTLDVTPV-IYAGATSKNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTLPFVKTVP 1660
             M +S++   P  +Y+ A S +     A TT    +    T  +    TE TL       
Sbjct: 4899 SMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITT 4958

Query: 1661 TTIMAGIVTPFV-----------GTTAFSPLSSKSTGAISSIPKTTFSPFLSATQQSSQA 1709
            ++      TP              +T    LS +ST   SS   T  + F  +   S  +
Sbjct: 4959 SSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHS 5018

Query: 1710 DEATTLGILSGITNRSLSTVNSGTGVALTDTYSRITVPENMLSPTHADSLH-------TS 1762
             ++T      G T+  L    + T +    T    +      +P  A S         T+
Sbjct: 5019 QQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLPARSTASDLVGEPTT 5078

Query: 1763 FNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLLEKTSLTNYATSL 1814
            F I  SP+ T+   AS  T  +   +  F ++    ++++   SL   A  L
Sbjct: 5079 FYISPSPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIVSTESLETLAPGL 5130



 Score = 92.8 bits (229), Expect = 5e-18
 Identities = 201/823 (24%), Positives = 315/823 (38%), Gaps = 117/823 (14%)

Query: 1548 LKSPCTATSGPMSEMSSIPVNNSAFTPATVSSDTSTRVGLFSTLLSSVTPRTTMTMQT-S 1606
            L     A      E     +N+S F+  +  + ++    +     S+ TP ++    T S
Sbjct: 134  LSEQARAAGAREKERQETVINHSTFSGFSQITGSTVNTSIGGNTTSASTPSSSDPFTTFS 193

Query: 1607 TLDVTPVIYAGATSKNKMVSSAFTTEMIEAPS------RITPTTFLSPTEPTLPFV---K 1657
               V+     G+T+    + S+  +   E  +        T TT       T  FV   K
Sbjct: 194  DYGVSVTFITGSTATKHFLDSSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPK 253

Query: 1658 TVPTTIMAGIVTPFVGTTAFSPLSSKSTGAISS--IPKTTFSPFLSATQQSSQADEATTL 1715
            T P T  +   T   G+T  + LS KST   SS   P  T SP  + T  S  ++++TT 
Sbjct: 254  TSPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDRTLSP--ARTTSSGVSEKSTTS 311

Query: 1716 GILSGITNRSLSTVNSGTGVALTDTYSRITVPENMLSPTHADSLHTSFNIQVSPSLTSFK 1775
                G T+           +A  D+    T+P      T + S+  S +  +SP  T+  
Sbjct: 312  HSRPGPTHT----------IAFPDS---TTMPGVSQESTASHSIPGSTDTTLSPGTTT-P 357

Query: 1776 SASGPTKNVKTTTNCFSSNTRKMTSLLEKTSLTNYATSLNTPVSYPPWTPSSATLP-SLT 1834
            S+ GP    ++TT   S    K T L + T+ T+     +TPV     +P +   P S T
Sbjct: 358  SSLGP----ESTTFHSSPGYTKTTRLPDNTT-TSGLLEASTPVHSSTGSPHTTLSPSSST 412

Query: 1835 SFVYSPHSTEAEISTPKTSPPPTSQMVEFPVLGTRMTSS-NTQPLLMTSWNIPTAEGSQ- 1892
            +    P + ++  S+  TSP P+     F  L T   SS ++ P    S +  T   S+ 
Sbjct: 413  THEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEE 472

Query: 1893 ------FPISTTINVP-----TSNEMETET-LHLVPGPLSTFTASQTGLVSKDVMAMSSI 1940
                   P++T    P     TS  +E  T  H  PG   T    ++   S      ++ 
Sbjct: 473  STPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATF 532

Query: 1941 PMSGILPNHGLSENPSLSTSL--RAITSTLADVKHTF---------------------EK 1977
              S     H  S  PS + +L   +  S+L   + T                      + 
Sbjct: 533  HGS---TTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDA 589

Query: 1978 MTTSVTPGTTLPSILSGATSGSVISKSPILTWLL---SSLPSGSPPAT----------VS 2024
            M T+V P  + PS+L G ++ S IS   + T  L   ++ P  S  +T           +
Sbjct: 590  MATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTT 649

Query: 2025 NAPHVMTSSTVEVSKSTFLTSDMISAH--PFTNLTTLPSATMSTILTRTIPTPTLGGITT 2082
            + P  MTSS V   +ST   S   S H   F   TT+P  +  +  + + P PT   ++ 
Sbjct: 650  HLPASMTSSGVS-EESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSP 708

Query: 2083 GFPTSLPMSINVTDDIVYISTHPEASSRTTITANPRTVSHPSSFSRKTMSPSTTDHTLSV 2142
            G  T+  +    T       + P  S+ TT+  +  T S     S    S + + HT   
Sbjct: 709  GSTTASSLGPEYTT----FHSRP-GSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLS 763

Query: 2143 GAMPLP---SSTITSSWNRIPTASSPSTLIIPKPTLDSLLNIMTTT----STVPGASFPL 2195
             A        ST   SW      SS  T   P  T  + +   TT+    S++P      
Sbjct: 764  PAGSTTRQGESTTFHSW-----PSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISA 818

Query: 2196 IST--GVTYPFTATVSSPISSFFETTWLDSTPSFLSTEASTSPTATKSTVSFYNVEMSFS 2253
             ST  G+    T   SSP S+         T S    E++TS ++T  T+S  +   + S
Sbjct: 819  RSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTIS--SAPSTTS 876

Query: 2254 VFVEEP----RIPITSVINEFTENSLNSIFQNSEFSLATLETQ 2292
              VEEP      P ++    F ++S  S    SE S A+  +Q
Sbjct: 877  ALVEEPTSYHSSPGSTATTHFPDSSTTS--GRSEESTASHSSQ 917


>gi|224809323 G protein-coupled receptor 56 isoform b precursor [Homo
            sapiens]
          Length = 687

 Score =  221 bits (563), Expect = 9e-57
 Identities = 142/475 (29%), Positives = 242/475 (50%), Gaps = 35/475 (7%)

Query: 2536 SNEILRIIERTGHKMEFSGQIANLTVAGLALAVLRGDHTFDGMAFSIHSYEEGTDPEIFL 2595
            +++ L+ +E     + F G + +     +   V +   T       IHS +E    EI  
Sbjct: 205  ASQQLQSLESKLTSVRFMGDMVSFEEDRINATVWKLQPTAGLQDLHIHSRQEEEQSEI-- 262

Query: 2596 GNVPVGGILASIYLPKSLTERIPLSNLQT---ILFNFFGQTSLFKTKNVTKALTTYVVSA 2652
                   +  S+ LP++L +R    + +    +L   F   +LF+ KN ++ L   V+  
Sbjct: 263  -------MEYSVLLPRTLFQRTKGRSGEAEKRLLLVDFSSQALFQDKNSSQVLGEKVLGI 315

Query: 2653 SISDDMFIQNLADPVVITLQHIGGNQNYGQVHCAFW-DFENNNGLGGWNSSGCKVKETNV 2711
             + +   + NL +PVV+T QH    +N   + C FW +    +  G W+S+GC+      
Sbjct: 316  VVQNTK-VANLTEPVVLTFQHQLQPKNV-TLQCVFWVEDPTLSSPGHWSSAGCETVRRET 373

Query: 2712 NYTICQCDHLTHFGVLMDLSRSTVDSVNEQILALITYTGCGISSIFLGVAVVTYIAFHKL 2771
              T C C+HLT+F VLM +S   VD+V++  L+L++Y GC +S++   V +  Y+   + 
Sbjct: 374  Q-TSCFCNHLTYFAVLM-VSSVEVDAVHKHYLSLLSYVGCVVSALACLVTIAAYLCSRRK 431

Query: 2772 RKDYPAKILINLCTALLMLNLVFLINSWLSSFQKVGVCITAAVALHYFLLVSFTWMGLEA 2831
             +DY  K+ +NL  A+ +L+  FL++  ++       C  +A+ LH+ LL   +WMGLE 
Sbjct: 432  PRDYTIKVHMNLLLAVFLLDTSFLLSEPVALTGSEAGCRASAIFLHFSLLTCLSWMGLEG 491

Query: 2832 VHMYLALVKVFNIYIPNYILKFCLVGWGIPAIMVAITVSVKKDLYGTL---SPTTP---- 2884
             ++Y  +V+VF  Y+P Y+LK   +GWG P  +V +   V  D YG +      TP    
Sbjct: 492  YNLYRLVVEVFGTYVPGYLLKLSAMGWGFPIFLVTLVALVDVDNYGPIILAVHRTPEGVI 551

Query: 2885 ---FCWIKDDSIFYISVVAYFCLIFLMNLSMFCTVLVQLNSVKSQIQKTRRKMILHDLKG 2941
                CWI+D  + YI+ +  F L+FL N++M  T++VQ+  ++   QK    + L     
Sbjct: 552  YPSMCWIRDSLVSYITNLGLFSLVFLFNMAMLATMVVQILRLRPHTQKWSHVLTL----- 606

Query: 2942 TMSLTFLLGLTWGFAFFAW--GPMRNFFLYLFAIFNTLQGFFIFVFHCVMKESVR 2994
             + L+ +LGL W   FF++  G  +   LYLF+I  + QGF IF+++  M+   R
Sbjct: 607  -LGLSLVLGLPWALIFFSFASGTFQLVVLYLFSIITSFQGFLIFIWYWSMRLQAR 660


>gi|224809320 G protein-coupled receptor 56 isoform c precursor [Homo
            sapiens]
          Length = 692

 Score =  221 bits (563), Expect = 9e-57
 Identities = 142/475 (29%), Positives = 242/475 (50%), Gaps = 35/475 (7%)

Query: 2536 SNEILRIIERTGHKMEFSGQIANLTVAGLALAVLRGDHTFDGMAFSIHSYEEGTDPEIFL 2595
            +++ L+ +E     + F G + +     +   V +   T       IHS +E    EI  
Sbjct: 210  ASQQLQSLESKLTSVRFMGDMVSFEEDRINATVWKLQPTAGLQDLHIHSRQEEEQSEI-- 267

Query: 2596 GNVPVGGILASIYLPKSLTERIPLSNLQT---ILFNFFGQTSLFKTKNVTKALTTYVVSA 2652
                   +  S+ LP++L +R    + +    +L   F   +LF+ KN ++ L   V+  
Sbjct: 268  -------MEYSVLLPRTLFQRTKGRSGEAEKRLLLVDFSSQALFQDKNSSQVLGEKVLGI 320

Query: 2653 SISDDMFIQNLADPVVITLQHIGGNQNYGQVHCAFW-DFENNNGLGGWNSSGCKVKETNV 2711
             + +   + NL +PVV+T QH    +N   + C FW +    +  G W+S+GC+      
Sbjct: 321  VVQNTK-VANLTEPVVLTFQHQLQPKNV-TLQCVFWVEDPTLSSPGHWSSAGCETVRRET 378

Query: 2712 NYTICQCDHLTHFGVLMDLSRSTVDSVNEQILALITYTGCGISSIFLGVAVVTYIAFHKL 2771
              T C C+HLT+F VLM +S   VD+V++  L+L++Y GC +S++   V +  Y+   + 
Sbjct: 379  Q-TSCFCNHLTYFAVLM-VSSVEVDAVHKHYLSLLSYVGCVVSALACLVTIAAYLCSRRK 436

Query: 2772 RKDYPAKILINLCTALLMLNLVFLINSWLSSFQKVGVCITAAVALHYFLLVSFTWMGLEA 2831
             +DY  K+ +NL  A+ +L+  FL++  ++       C  +A+ LH+ LL   +WMGLE 
Sbjct: 437  PRDYTIKVHMNLLLAVFLLDTSFLLSEPVALTGSEAGCRASAIFLHFSLLTCLSWMGLEG 496

Query: 2832 VHMYLALVKVFNIYIPNYILKFCLVGWGIPAIMVAITVSVKKDLYGTL---SPTTP---- 2884
             ++Y  +V+VF  Y+P Y+LK   +GWG P  +V +   V  D YG +      TP    
Sbjct: 497  YNLYRLVVEVFGTYVPGYLLKLSAMGWGFPIFLVTLVALVDVDNYGPIILAVHRTPEGVI 556

Query: 2885 ---FCWIKDDSIFYISVVAYFCLIFLMNLSMFCTVLVQLNSVKSQIQKTRRKMILHDLKG 2941
                CWI+D  + YI+ +  F L+FL N++M  T++VQ+  ++   QK    + L     
Sbjct: 557  YPSMCWIRDSLVSYITNLGLFSLVFLFNMAMLATMVVQILRLRPHTQKWSHVLTL----- 611

Query: 2942 TMSLTFLLGLTWGFAFFAW--GPMRNFFLYLFAIFNTLQGFFIFVFHCVMKESVR 2994
             + L+ +LGL W   FF++  G  +   LYLF+I  + QGF IF+++  M+   R
Sbjct: 612  -LGLSLVLGLPWALIFFSFASGTFQLVVLYLFSIITSFQGFLIFIWYWSMRLQAR 665


>gi|224809318 G protein-coupled receptor 56 isoform b precursor [Homo
            sapiens]
          Length = 687

 Score =  221 bits (563), Expect = 9e-57
 Identities = 142/475 (29%), Positives = 242/475 (50%), Gaps = 35/475 (7%)

Query: 2536 SNEILRIIERTGHKMEFSGQIANLTVAGLALAVLRGDHTFDGMAFSIHSYEEGTDPEIFL 2595
            +++ L+ +E     + F G + +     +   V +   T       IHS +E    EI  
Sbjct: 205  ASQQLQSLESKLTSVRFMGDMVSFEEDRINATVWKLQPTAGLQDLHIHSRQEEEQSEI-- 262

Query: 2596 GNVPVGGILASIYLPKSLTERIPLSNLQT---ILFNFFGQTSLFKTKNVTKALTTYVVSA 2652
                   +  S+ LP++L +R    + +    +L   F   +LF+ KN ++ L   V+  
Sbjct: 263  -------MEYSVLLPRTLFQRTKGRSGEAEKRLLLVDFSSQALFQDKNSSQVLGEKVLGI 315

Query: 2653 SISDDMFIQNLADPVVITLQHIGGNQNYGQVHCAFW-DFENNNGLGGWNSSGCKVKETNV 2711
             + +   + NL +PVV+T QH    +N   + C FW +    +  G W+S+GC+      
Sbjct: 316  VVQNTK-VANLTEPVVLTFQHQLQPKNV-TLQCVFWVEDPTLSSPGHWSSAGCETVRRET 373

Query: 2712 NYTICQCDHLTHFGVLMDLSRSTVDSVNEQILALITYTGCGISSIFLGVAVVTYIAFHKL 2771
              T C C+HLT+F VLM +S   VD+V++  L+L++Y GC +S++   V +  Y+   + 
Sbjct: 374  Q-TSCFCNHLTYFAVLM-VSSVEVDAVHKHYLSLLSYVGCVVSALACLVTIAAYLCSRRK 431

Query: 2772 RKDYPAKILINLCTALLMLNLVFLINSWLSSFQKVGVCITAAVALHYFLLVSFTWMGLEA 2831
             +DY  K+ +NL  A+ +L+  FL++  ++       C  +A+ LH+ LL   +WMGLE 
Sbjct: 432  PRDYTIKVHMNLLLAVFLLDTSFLLSEPVALTGSEAGCRASAIFLHFSLLTCLSWMGLEG 491

Query: 2832 VHMYLALVKVFNIYIPNYILKFCLVGWGIPAIMVAITVSVKKDLYGTL---SPTTP---- 2884
             ++Y  +V+VF  Y+P Y+LK   +GWG P  +V +   V  D YG +      TP    
Sbjct: 492  YNLYRLVVEVFGTYVPGYLLKLSAMGWGFPIFLVTLVALVDVDNYGPIILAVHRTPEGVI 551

Query: 2885 ---FCWIKDDSIFYISVVAYFCLIFLMNLSMFCTVLVQLNSVKSQIQKTRRKMILHDLKG 2941
                CWI+D  + YI+ +  F L+FL N++M  T++VQ+  ++   QK    + L     
Sbjct: 552  YPSMCWIRDSLVSYITNLGLFSLVFLFNMAMLATMVVQILRLRPHTQKWSHVLTL----- 606

Query: 2942 TMSLTFLLGLTWGFAFFAW--GPMRNFFLYLFAIFNTLQGFFIFVFHCVMKESVR 2994
             + L+ +LGL W   FF++  G  +   LYLF+I  + QGF IF+++  M+   R
Sbjct: 607  -LGLSLVLGLPWALIFFSFASGTFQLVVLYLFSIITSFQGFLIFIWYWSMRLQAR 660


>gi|224809314 G protein-coupled receptor 56 isoform b precursor [Homo
            sapiens]
          Length = 687

 Score =  221 bits (563), Expect = 9e-57
 Identities = 142/475 (29%), Positives = 242/475 (50%), Gaps = 35/475 (7%)

Query: 2536 SNEILRIIERTGHKMEFSGQIANLTVAGLALAVLRGDHTFDGMAFSIHSYEEGTDPEIFL 2595
            +++ L+ +E     + F G + +     +   V +   T       IHS +E    EI  
Sbjct: 205  ASQQLQSLESKLTSVRFMGDMVSFEEDRINATVWKLQPTAGLQDLHIHSRQEEEQSEI-- 262

Query: 2596 GNVPVGGILASIYLPKSLTERIPLSNLQT---ILFNFFGQTSLFKTKNVTKALTTYVVSA 2652
                   +  S+ LP++L +R    + +    +L   F   +LF+ KN ++ L   V+  
Sbjct: 263  -------MEYSVLLPRTLFQRTKGRSGEAEKRLLLVDFSSQALFQDKNSSQVLGEKVLGI 315

Query: 2653 SISDDMFIQNLADPVVITLQHIGGNQNYGQVHCAFW-DFENNNGLGGWNSSGCKVKETNV 2711
             + +   + NL +PVV+T QH    +N   + C FW +    +  G W+S+GC+      
Sbjct: 316  VVQNTK-VANLTEPVVLTFQHQLQPKNV-TLQCVFWVEDPTLSSPGHWSSAGCETVRRET 373

Query: 2712 NYTICQCDHLTHFGVLMDLSRSTVDSVNEQILALITYTGCGISSIFLGVAVVTYIAFHKL 2771
              T C C+HLT+F VLM +S   VD+V++  L+L++Y GC +S++   V +  Y+   + 
Sbjct: 374  Q-TSCFCNHLTYFAVLM-VSSVEVDAVHKHYLSLLSYVGCVVSALACLVTIAAYLCSRRK 431

Query: 2772 RKDYPAKILINLCTALLMLNLVFLINSWLSSFQKVGVCITAAVALHYFLLVSFTWMGLEA 2831
             +DY  K+ +NL  A+ +L+  FL++  ++       C  +A+ LH+ LL   +WMGLE 
Sbjct: 432  PRDYTIKVHMNLLLAVFLLDTSFLLSEPVALTGSEAGCRASAIFLHFSLLTCLSWMGLEG 491

Query: 2832 VHMYLALVKVFNIYIPNYILKFCLVGWGIPAIMVAITVSVKKDLYGTL---SPTTP---- 2884
             ++Y  +V+VF  Y+P Y+LK   +GWG P  +V +   V  D YG +      TP    
Sbjct: 492  YNLYRLVVEVFGTYVPGYLLKLSAMGWGFPIFLVTLVALVDVDNYGPIILAVHRTPEGVI 551

Query: 2885 ---FCWIKDDSIFYISVVAYFCLIFLMNLSMFCTVLVQLNSVKSQIQKTRRKMILHDLKG 2941
                CWI+D  + YI+ +  F L+FL N++M  T++VQ+  ++   QK    + L     
Sbjct: 552  YPSMCWIRDSLVSYITNLGLFSLVFLFNMAMLATMVVQILRLRPHTQKWSHVLTL----- 606

Query: 2942 TMSLTFLLGLTWGFAFFAW--GPMRNFFLYLFAIFNTLQGFFIFVFHCVMKESVR 2994
             + L+ +LGL W   FF++  G  +   LYLF+I  + QGF IF+++  M+   R
Sbjct: 607  -LGLSLVLGLPWALIFFSFASGTFQLVVLYLFSIITSFQGFLIFIWYWSMRLQAR 660


>gi|41584198 G protein-coupled receptor 56 isoform b precursor [Homo
            sapiens]
          Length = 687

 Score =  221 bits (563), Expect = 9e-57
 Identities = 142/475 (29%), Positives = 242/475 (50%), Gaps = 35/475 (7%)

Query: 2536 SNEILRIIERTGHKMEFSGQIANLTVAGLALAVLRGDHTFDGMAFSIHSYEEGTDPEIFL 2595
            +++ L+ +E     + F G + +     +   V +   T       IHS +E    EI  
Sbjct: 205  ASQQLQSLESKLTSVRFMGDMVSFEEDRINATVWKLQPTAGLQDLHIHSRQEEEQSEI-- 262

Query: 2596 GNVPVGGILASIYLPKSLTERIPLSNLQT---ILFNFFGQTSLFKTKNVTKALTTYVVSA 2652
                   +  S+ LP++L +R    + +    +L   F   +LF+ KN ++ L   V+  
Sbjct: 263  -------MEYSVLLPRTLFQRTKGRSGEAEKRLLLVDFSSQALFQDKNSSQVLGEKVLGI 315

Query: 2653 SISDDMFIQNLADPVVITLQHIGGNQNYGQVHCAFW-DFENNNGLGGWNSSGCKVKETNV 2711
             + +   + NL +PVV+T QH    +N   + C FW +    +  G W+S+GC+      
Sbjct: 316  VVQNTK-VANLTEPVVLTFQHQLQPKNV-TLQCVFWVEDPTLSSPGHWSSAGCETVRRET 373

Query: 2712 NYTICQCDHLTHFGVLMDLSRSTVDSVNEQILALITYTGCGISSIFLGVAVVTYIAFHKL 2771
              T C C+HLT+F VLM +S   VD+V++  L+L++Y GC +S++   V +  Y+   + 
Sbjct: 374  Q-TSCFCNHLTYFAVLM-VSSVEVDAVHKHYLSLLSYVGCVVSALACLVTIAAYLCSRRK 431

Query: 2772 RKDYPAKILINLCTALLMLNLVFLINSWLSSFQKVGVCITAAVALHYFLLVSFTWMGLEA 2831
             +DY  K+ +NL  A+ +L+  FL++  ++       C  +A+ LH+ LL   +WMGLE 
Sbjct: 432  PRDYTIKVHMNLLLAVFLLDTSFLLSEPVALTGSEAGCRASAIFLHFSLLTCLSWMGLEG 491

Query: 2832 VHMYLALVKVFNIYIPNYILKFCLVGWGIPAIMVAITVSVKKDLYGTL---SPTTP---- 2884
             ++Y  +V+VF  Y+P Y+LK   +GWG P  +V +   V  D YG +      TP    
Sbjct: 492  YNLYRLVVEVFGTYVPGYLLKLSAMGWGFPIFLVTLVALVDVDNYGPIILAVHRTPEGVI 551

Query: 2885 ---FCWIKDDSIFYISVVAYFCLIFLMNLSMFCTVLVQLNSVKSQIQKTRRKMILHDLKG 2941
                CWI+D  + YI+ +  F L+FL N++M  T++VQ+  ++   QK    + L     
Sbjct: 552  YPSMCWIRDSLVSYITNLGLFSLVFLFNMAMLATMVVQILRLRPHTQKWSHVLTL----- 606

Query: 2942 TMSLTFLLGLTWGFAFFAW--GPMRNFFLYLFAIFNTLQGFFIFVFHCVMKESVR 2994
             + L+ +LGL W   FF++  G  +   LYLF+I  + QGF IF+++  M+   R
Sbjct: 607  -LGLSLVLGLPWALIFFSFASGTFQLVVLYLFSIITSFQGFLIFIWYWSMRLQAR 660


>gi|41584202 G protein-coupled receptor 56 isoform b precursor [Homo
            sapiens]
          Length = 687

 Score =  221 bits (563), Expect = 9e-57
 Identities = 142/475 (29%), Positives = 242/475 (50%), Gaps = 35/475 (7%)

Query: 2536 SNEILRIIERTGHKMEFSGQIANLTVAGLALAVLRGDHTFDGMAFSIHSYEEGTDPEIFL 2595
            +++ L+ +E     + F G + +     +   V +   T       IHS +E    EI  
Sbjct: 205  ASQQLQSLESKLTSVRFMGDMVSFEEDRINATVWKLQPTAGLQDLHIHSRQEEEQSEI-- 262

Query: 2596 GNVPVGGILASIYLPKSLTERIPLSNLQT---ILFNFFGQTSLFKTKNVTKALTTYVVSA 2652
                   +  S+ LP++L +R    + +    +L   F   +LF+ KN ++ L   V+  
Sbjct: 263  -------MEYSVLLPRTLFQRTKGRSGEAEKRLLLVDFSSQALFQDKNSSQVLGEKVLGI 315

Query: 2653 SISDDMFIQNLADPVVITLQHIGGNQNYGQVHCAFW-DFENNNGLGGWNSSGCKVKETNV 2711
             + +   + NL +PVV+T QH    +N   + C FW +    +  G W+S+GC+      
Sbjct: 316  VVQNTK-VANLTEPVVLTFQHQLQPKNV-TLQCVFWVEDPTLSSPGHWSSAGCETVRRET 373

Query: 2712 NYTICQCDHLTHFGVLMDLSRSTVDSVNEQILALITYTGCGISSIFLGVAVVTYIAFHKL 2771
              T C C+HLT+F VLM +S   VD+V++  L+L++Y GC +S++   V +  Y+   + 
Sbjct: 374  Q-TSCFCNHLTYFAVLM-VSSVEVDAVHKHYLSLLSYVGCVVSALACLVTIAAYLCSRRK 431

Query: 2772 RKDYPAKILINLCTALLMLNLVFLINSWLSSFQKVGVCITAAVALHYFLLVSFTWMGLEA 2831
             +DY  K+ +NL  A+ +L+  FL++  ++       C  +A+ LH+ LL   +WMGLE 
Sbjct: 432  PRDYTIKVHMNLLLAVFLLDTSFLLSEPVALTGSEAGCRASAIFLHFSLLTCLSWMGLEG 491

Query: 2832 VHMYLALVKVFNIYIPNYILKFCLVGWGIPAIMVAITVSVKKDLYGTL---SPTTP---- 2884
             ++Y  +V+VF  Y+P Y+LK   +GWG P  +V +   V  D YG +      TP    
Sbjct: 492  YNLYRLVVEVFGTYVPGYLLKLSAMGWGFPIFLVTLVALVDVDNYGPIILAVHRTPEGVI 551

Query: 2885 ---FCWIKDDSIFYISVVAYFCLIFLMNLSMFCTVLVQLNSVKSQIQKTRRKMILHDLKG 2941
                CWI+D  + YI+ +  F L+FL N++M  T++VQ+  ++   QK    + L     
Sbjct: 552  YPSMCWIRDSLVSYITNLGLFSLVFLFNMAMLATMVVQILRLRPHTQKWSHVLTL----- 606

Query: 2942 TMSLTFLLGLTWGFAFFAW--GPMRNFFLYLFAIFNTLQGFFIFVFHCVMKESVR 2994
             + L+ +LGL W   FF++  G  +   LYLF+I  + QGF IF+++  M+   R
Sbjct: 607  -LGLSLVLGLPWALIFFSFASGTFQLVVLYLFSIITSFQGFLIFIWYWSMRLQAR 660


>gi|41584200 G protein-coupled receptor 56 isoform a precursor [Homo
            sapiens]
          Length = 693

 Score =  214 bits (546), Expect = 8e-55
 Identities = 142/481 (29%), Positives = 242/481 (50%), Gaps = 41/481 (8%)

Query: 2536 SNEILRIIERTGHKMEFSGQIANLTVAGLALAVLRGDHTFDGMAFSIHSYEEGTDPEIFL 2595
            +++ L+ +E     + F G + +     +   V +   T       IHS +E    EI  
Sbjct: 205  ASQQLQSLESKLTSVRFMGDMVSFEEDRINATVWKLQPTAGLQDLHIHSRQEEEQSEI-- 262

Query: 2596 GNVPVGGILASIYLPKSLTERIPLSNLQT---ILFNFFGQTSLFKTKNVTKALTTYVVSA 2652
                   +  S+ LP++L +R    + +    +L   F   +LF+ KN ++ L   V+  
Sbjct: 263  -------MEYSVLLPRTLFQRTKGRSGEAEKRLLLVDFSSQALFQDKNSSQVLGEKVLGI 315

Query: 2653 SISDDMFIQNLADPVVITLQHIGGNQNYGQVHCAFW-DFENNNGLGGWNSSGCKVKETNV 2711
             + +   + NL +PVV+T QH    +N   + C FW +    +  G W+S+GC+      
Sbjct: 316  VVQNTK-VANLTEPVVLTFQHQLQPKNV-TLQCVFWVEDPTLSSPGHWSSAGCETVRRET 373

Query: 2712 NYTICQCDHLTHFGVLMDLSRSTVDSVNEQILALITYTGCGISSIFLGVAVVTYIAFH-- 2769
              T C C+HLT+F VLM +S   VD+V++  L+L++Y GC +S++   V +  Y+     
Sbjct: 374  Q-TSCFCNHLTYFAVLM-VSSVEVDAVHKHYLSLLSYVGCVVSALACLVTIAAYLCSRVP 431

Query: 2770 ----KLRKDYPAKILINLCTALLMLNLVFLINSWLSSFQKVGVCITAAVALHYFLLVSFT 2825
                +  +DY  K+ +NL  A+ +L+  FL++  ++       C  +A+ LH+ LL   +
Sbjct: 432  LPCRRKPRDYTIKVHMNLLLAVFLLDTSFLLSEPVALTGSEAGCRASAIFLHFSLLTCLS 491

Query: 2826 WMGLEAVHMYLALVKVFNIYIPNYILKFCLVGWGIPAIMVAITVSVKKDLYGTL---SPT 2882
            WMGLE  ++Y  +V+VF  Y+P Y+LK   +GWG P  +V +   V  D YG +      
Sbjct: 492  WMGLEGYNLYRLVVEVFGTYVPGYLLKLSAMGWGFPIFLVTLVALVDVDNYGPIILAVHR 551

Query: 2883 TP-------FCWIKDDSIFYISVVAYFCLIFLMNLSMFCTVLVQLNSVKSQIQKTRRKMI 2935
            TP        CWI+D  + YI+ +  F L+FL N++M  T++VQ+  ++   QK    + 
Sbjct: 552  TPEGVIYPSMCWIRDSLVSYITNLGLFSLVFLFNMAMLATMVVQILRLRPHTQKWSHVLT 611

Query: 2936 LHDLKGTMSLTFLLGLTWGFAFFAW--GPMRNFFLYLFAIFNTLQGFFIFVFHCVMKESV 2993
            L      + L+ +LGL W   FF++  G  +   LYLF+I  + QGF IF+++  M+   
Sbjct: 612  L------LGLSLVLGLPWALIFFSFASGTFQLVVLYLFSIITSFQGFLIFIWYWSMRLQA 665

Query: 2994 R 2994
            R
Sbjct: 666  R 666


>gi|224809316 G protein-coupled receptor 56 isoform a precursor [Homo
            sapiens]
          Length = 693

 Score =  214 bits (546), Expect = 8e-55
 Identities = 142/481 (29%), Positives = 242/481 (50%), Gaps = 41/481 (8%)

Query: 2536 SNEILRIIERTGHKMEFSGQIANLTVAGLALAVLRGDHTFDGMAFSIHSYEEGTDPEIFL 2595
            +++ L+ +E     + F G + +     +   V +   T       IHS +E    EI  
Sbjct: 205  ASQQLQSLESKLTSVRFMGDMVSFEEDRINATVWKLQPTAGLQDLHIHSRQEEEQSEI-- 262

Query: 2596 GNVPVGGILASIYLPKSLTERIPLSNLQT---ILFNFFGQTSLFKTKNVTKALTTYVVSA 2652
                   +  S+ LP++L +R    + +    +L   F   +LF+ KN ++ L   V+  
Sbjct: 263  -------MEYSVLLPRTLFQRTKGRSGEAEKRLLLVDFSSQALFQDKNSSQVLGEKVLGI 315

Query: 2653 SISDDMFIQNLADPVVITLQHIGGNQNYGQVHCAFW-DFENNNGLGGWNSSGCKVKETNV 2711
             + +   + NL +PVV+T QH    +N   + C FW +    +  G W+S+GC+      
Sbjct: 316  VVQNTK-VANLTEPVVLTFQHQLQPKNV-TLQCVFWVEDPTLSSPGHWSSAGCETVRRET 373

Query: 2712 NYTICQCDHLTHFGVLMDLSRSTVDSVNEQILALITYTGCGISSIFLGVAVVTYIAFH-- 2769
              T C C+HLT+F VLM +S   VD+V++  L+L++Y GC +S++   V +  Y+     
Sbjct: 374  Q-TSCFCNHLTYFAVLM-VSSVEVDAVHKHYLSLLSYVGCVVSALACLVTIAAYLCSRVP 431

Query: 2770 ----KLRKDYPAKILINLCTALLMLNLVFLINSWLSSFQKVGVCITAAVALHYFLLVSFT 2825
                +  +DY  K+ +NL  A+ +L+  FL++  ++       C  +A+ LH+ LL   +
Sbjct: 432  LPCRRKPRDYTIKVHMNLLLAVFLLDTSFLLSEPVALTGSEAGCRASAIFLHFSLLTCLS 491

Query: 2826 WMGLEAVHMYLALVKVFNIYIPNYILKFCLVGWGIPAIMVAITVSVKKDLYGTL---SPT 2882
            WMGLE  ++Y  +V+VF  Y+P Y+LK   +GWG P  +V +   V  D YG +      
Sbjct: 492  WMGLEGYNLYRLVVEVFGTYVPGYLLKLSAMGWGFPIFLVTLVALVDVDNYGPIILAVHR 551

Query: 2883 TP-------FCWIKDDSIFYISVVAYFCLIFLMNLSMFCTVLVQLNSVKSQIQKTRRKMI 2935
            TP        CWI+D  + YI+ +  F L+FL N++M  T++VQ+  ++   QK    + 
Sbjct: 552  TPEGVIYPSMCWIRDSLVSYITNLGLFSLVFLFNMAMLATMVVQILRLRPHTQKWSHVLT 611

Query: 2936 LHDLKGTMSLTFLLGLTWGFAFFAW--GPMRNFFLYLFAIFNTLQGFFIFVFHCVMKESV 2993
            L      + L+ +LGL W   FF++  G  +   LYLF+I  + QGF IF+++  M+   
Sbjct: 612  L------LGLSLVLGLPWALIFFSFASGTFQLVVLYLFSIITSFQGFLIFIWYWSMRLQA 665

Query: 2994 R 2994
            R
Sbjct: 666  R 666


>gi|24475871 G protein-coupled receptor 114 [Homo sapiens]
          Length = 528

 Score =  213 bits (543), Expect = 2e-54
 Identities = 125/374 (33%), Positives = 194/374 (51%), Gaps = 19/374 (5%)

Query: 2629 FFGQTSLFKTKNVTKALTTYVVSASISDDMFIQNLADPVVITLQHIGGNQNYGQVHCAFW 2688
            +F  T  FK +N +  L  YV+ A +S    + NL DPV I+  H    + Y  + C FW
Sbjct: 135  YFSNTHFFKDENNSSLLNNYVLGAQLSHG-HVNNLRDPVNISFWHNQSLEGY-TLTCVFW 192

Query: 2689 -DFENNNGLGGWNSSGCKVKETNVNYTICQCDHLTHFGVLMDLSRSTVDSVNEQILALIT 2747
             +       GGW+  GC+ ++ + +  +C+C+HLT+F VLM LS + V +     L  I+
Sbjct: 193  KEGARKQPWGGWSPEGCRTEQPSHSQVLCRCNHLTYFAVLMQLSPALVPAELLAPLTYIS 252

Query: 2748 YTGCGISSIFLGVAVVTYIAFHKLRKDYPAKILINLCTALLMLNLVFLINSWLSSFQKVG 2807
              GC IS +   + V+ +  F K + D   +I +NL  ++L+LN+ FL++   +     G
Sbjct: 253  LVGCSISIVASLITVLLHFHFRK-QSDSLTRIHMNLHASVLLLNIAFLLSPAFAMSPVPG 311

Query: 2808 -VCITAAVALHYFLLVSFTWMGLEAVHMYLALVKVFNIYIPNYILKFCLVGWGIPAIMVA 2866
              C   A ALHY LL   TWM +E  ++YL L +V+NIYI  Y+ K  ++GWG PA++V 
Sbjct: 312  SACTALAAALHYALLSCLTWMAIEGFNLYLLLGRVYNIYIRRYVFKLGVLGWGAPALLVL 371

Query: 2867 ITVSVKKDLY-------------GTLSPTTPFCWIKDDSIFYISVVAYFCLIFLMNLSMF 2913
            +++SVK  +Y             GT       CW++   +  + V+ Y  L  L NL + 
Sbjct: 372  LSLSVKSSVYGPCTIPVFDSWENGTGFQNMSICWVRSPVVHSVLVMGYGGLTSLFNLVVL 431

Query: 2914 CTVLVQLNSVKSQIQKTRRKMILHDLKGTMSLTFLLGLTWGFAFFAWGPMRNFFLYLFAI 2973
               L  L  ++ +      +   HD    + LT LLG TW  AFF++G      L+LF I
Sbjct: 432  AWALWTLRRLRERADAPSVR-ACHDTVTVLGLTVLLGTTWALAFFSFGVFLLPQLFLFTI 490

Query: 2974 FNTLQGFFIFVFHC 2987
             N+L GFF+F++ C
Sbjct: 491  LNSLYGFFLFLWFC 504


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score =  211 bits (537), Expect = 9e-54
 Identities = 535/2288 (23%), Positives = 858/2288 (37%), Gaps = 392/2288 (17%)

Query: 230   VPENMTIQEKSTTVSQQIDMTTPSQITGVKPQNTAHSSTLLSQSIPIFATDYTTISYSNT 289
             VP      E +T +S+  +   PS  + +  + T+ SS+LLS  +P+            T
Sbjct: 9987  VPPRFLHSEMTTLMSRSPE--NPSWKSSLFVEKTSSSSSLLS--LPV------------T 10030

Query: 290   TSPPLETMTAQKILKTLVDETATFAVDVLSTSSAISLPTQSISIDNTTNSMKKTKSPSSE 349
             TSP + +   Q I  +    T+     ++ T+   + P  S+S  N + +  +  + S  
Sbjct: 10031 TSPSVSSTLPQSIPSSSFSVTSLLTPGMVKTTDTSTEPGTSLS-PNLSGTSVEILAASEV 10089

Query: 350   STKTTKMVEAMATEIFQPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFSTIES 409
             +T T K+  + +  +    T S+         + + S+ S     S  T      S++  
Sbjct: 10090 TTDTEKIHPSSSMAVTNVGTTSS--------GHELYSSVSIHSEPSKATYPVGTPSSMAE 10141

Query: 410   TSMSTTPCLKQKSTNTGALPISTAGQEFIESTAAGTVPWFTVEKT--SPASTHV------ 461
             TS+ST+     ++T   A P S     F ++  +      T   T  SP STH+      
Sbjct: 10142 TSISTSMPANFETTGFEAEPFSHLTSGFRKTNMSLDTSSVTPTNTPSSPGSTHLLQSSKT 10201

Query: 462   ---GTASSFPPE--PVLISTAAPVDSVFPRNQ----------TAFPLATTDMKIAFTVHS 506
                 +A +  P+  P    T  PVD + P N           T+FP +   M +  + H 
Sbjct: 10202 DFTSSAKTSSPDWPPASQYTEIPVDIITPFNASPSITESTGITSFPESRFTMSVTESTHH 10261

Query: 507   LTLPTRLIETTPAPRTAETELTSTNFQDVSLPRVEDAMSTSMSKETSSKTFSFLTSFSFT 566
             L+        T    +AET  T T      +P + +AM                TSF+ T
Sbjct: 10262 LS--------TDLLPSAETISTGT-----VMPSLSEAM----------------TSFATT 10292

Query: 567   GTESVQTVIDAEATRTALTPEITLASTVAETMLSSTITGRVYTQNTPTADGHLLTLMSTR 626
             G     +   +  +RT   P     ST+AE++ SST      +  T T    +  L    
Sbjct: 10293 GVPRAISGSGSPFSRTESGPGDATLSTIAESLPSSTPVPFSSSTFTTTDSSTIPALHEIT 10352

Query: 627   SAS-------TSKAPESGPTSTTDEAAHLFSSNETIWTSRPDQALLASMNTTTILTFVPN 679
             S+S       TS   ES   STT+    + S+ +T  +S+P +   + +  T +   V  
Sbjct: 10353 SSSATPYRVDTSLGTES---STTEGRLVMVSTLDT--SSQPGRTSSSPILDTRMTESVEL 10407

Query: 680   ENFTSAFHENTTYT---------EYLSATTN-------ITPLK--------ASPEGKGTT 715
                TSA+   +  T         E+++   N       I P+K        ASP+G  T 
Sbjct: 10408 GTVTSAYQVPSLSTRLTRTDGIMEHITKIPNEAAHRGTIRPVKGPQTSTSPASPKGLHTG 10467

Query: 716   ANDATTARYTTAVSKLTSPWFANFSIVSGTTSITNMPEFKLTTLLLKTIPMSTKPANELP 775
                      TT   K T+      S  + TTS+       LT L       ST P   + 
Sbjct: 10468 GTKRMET--TTTALKTTTTALKTTSRATLTTSVYTPTLGTLTPLNASMQMASTIPTEMMI 10525

Query: 776   LTPRETVVPSVDIISTLACIQPNFSTEESASETT------QTEINGAIVFGGTTTPVPKS 829
              TP   V P V   ++         T  +   TT      ++E   ++V   + +   +S
Sbjct: 10526 TTPY--VFPDVPETTSSLATSLGAETSTALPRTTPSVFNRESETTASLV---SRSGAERS 10580

Query: 830   ATTQRLNATVTRKEATSHYLMRKS-TIAAVAEVSP--FSTMLEVTDESAQR----VTASV 882
                Q L+ + +  + T+ +++  + TI  V++ +P  F + L+    +A      V++++
Sbjct: 10581 PVIQTLDVSSSEPDTTASWVIHPAETIPTVSKTTPNFFHSELDTVSSTATSHGADVSSAI 10640

Query: 883   TVSSFPDIEKLSTPLDNKTAT---------------TEVRESWLL--TKLVKTTPRSSYN 925
               +  P      TPL   + T               TE R +WL    +   T PR+  N
Sbjct: 10641 PTNISPSELDALTPLVTISGTDTSTTFPTLTKSPHETETRTTWLTHPAETSSTIPRTIPN 10700

Query: 926   EMTEMFNFNHTYVAHWTSETSEGISAGSPTSGSTHIFGEPLGASTTRISET--------- 976
                   +   +      +ETS  I   + + G+  +    + +S T  + T         
Sbjct: 10701 FSHHESDATPSIATSPGAETSSAIPIMTVSPGAEDLVTSQVTSSGTDRNMTIPTLTLSPG 10760

Query: 977   ------SFSTTPTDRTATSLSDGILPPQPT----------AAHSSAT----------PVP 1010
                   S  T P  +T++++    + P  +          AA +S T          P  
Sbjct: 10761 EPKTIASLVTHPEAQTSSAIPTSTISPAVSRLVTSMVTSLAAKTSTTNRALTNSPGEPAT 10820

Query: 1011  VTHMFSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVP----P 1066
                + + P   S  V   T +     S    + +TS  ++ S+   T   +  VP    P
Sbjct: 10821 TVSLVTHPAQTSPTVPWTTSIFFHSKSDTTPSMTTSHGAESSSAVPTPTVSTEVPGVVTP 10880

Query: 1067  LDQTA----STTIVIVPTHGDLIRTTSEATVISVRKTSMAVPSLTETPFHSLRLSTPVTA 1122
             L  ++    STTI I+        TT         + S A+P+ T +P     +++ VT+
Sbjct: 10881 LVTSSRAVISTTIPILTLSPGEPETTPSMATSHGEEASSAIPTPTVSPGVPGVVTSLVTS 10940

Query: 1123  KAETT-------LFSTSVDTVTPS---THTLVCSKPPPDNIPPA--------SSTHVIST 1164
                 T        FS      TPS   +H        P  +P          +S+  +++
Sbjct: 10941 SRAVTSTTIPILTFSLGEPETTPSMATSHGTEAGSAVPTVLPEVPGMVTSLVASSRAVTS 11000

Query: 1165  TSTPEATQPISQVEETSTYALSFPYTFSGG---------GVVASLAT---GTTETSVVD- 1211
             T+ P  T    + E T + A S     S           GVV SL T   G   TS+   
Sbjct: 11001 TTLPTLTLSPGEPETTPSMATSHGAEASSTVPTVSPEVPGVVTSLVTSSSGVNSTSIPTL 11060

Query: 1212  -------ETTPSHISAN--KLTTSVNSHISSSATYRVHTPV--SIQLVTSTSV----LSS 1256
                    ETTPS  +++  + +++V +   S     V TP+  S + VTST++    LSS
Sbjct: 11061 ILSPGELETTPSMATSHGAEASSAVPTPTVSPGVSGVVTPLVTSSRAVTSTTIPILTLSS 11120

Query: 1257  DKDQMTISLGKT---PRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQ-- 1311
              + + T S+  +     +  V  +SP     ++ S  T S  +T T  P  T ISS +  
Sbjct: 11121 SEPETTPSMATSHGVEASSAVLTVSPEVPGMVT-SLVTSSRAVTSTTIPTLT-ISSDEPE 11178

Query: 1312  ------THSPSEIPLGTPSDGNLASSPTSGSTQITPTLTSSNTVGVHIPEMSTSLGKTAL 1365
                   THS +++    P+   LA SPT     +T  +TSS +      E S     T  
Sbjct: 11179 TTTSLVTHSEAKMISAIPT---LAVSPTVQGL-VTSLVTSSGS------ETSAFSNLTVA 11228

Query: 1366  PSQALTITTFLC-PEKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSST 1424
              SQ  TI +++  P  E++S +P  T  T E   N + VTH     + +S +  TTS   
Sbjct: 11229 SSQPETIDSWVAHPGTEASSVVPTLTVSTGEPFTNISLVTHPA---ESSSTLPRTTSR-- 11283

Query: 1425  RISNPMDINTTFSHLHSLRTQPEVTSVASFISESTQTFPESLSLSTAGLYNDGFTVLSDR 1484
                        FSH   L T P  ++V S  +ES+     ++S    G+     T     
Sbjct: 11284 -----------FSH-SELDTMP--STVTSPEAESSSAISTTISPGIPGVLTSLVTSSGRD 11329

Query: 1485  ITTAFSVPNVPTMLPRESSMATSTPIYQMSSLPVNVTAFTSKKVSDTPPIVITKSSKTMH 1544
             I+  F  P VP   P ES    S          V   A TS  V  T P   + S     
Sbjct: 11330 ISATF--PTVPES-PHESEATASW---------VTHPAVTSTTVPRTTPNY-SHSEPDTT 11376

Query: 1545  PGCLKSPCTATSGPMSEMSSIPVNNSAFTPATVSSDTSTRVGLFSTLLSSVTPRTTMTMQ 1604
             P    SP    +     ++  P      T    SS T T + + +  LSS  P TT +  
Sbjct: 11377 PSIATSPGAEATSDFPTITVSPDVPDMVTSQVTSSGTDTSITIPTLTLSSGEPETTTSFI 11436

Query: 1605  T-------STLDVTPVIYAGATSKNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTLPFVK 1657
             T       S +   PV    +     +V S+ T      P+ +T T +  P    +  + 
Sbjct: 11437 TYSETHTSSAIPTLPVSPGASKMLTSLVISSGTDSTTTFPT-LTETPY-EPETTAIQLIH 11494

Query: 1658  TVPTTIMAGIVTPFVG-----TTAFSPLSSKSTGAISSIPKTTFSPFLS----ATQQSSQ 1708
                T  M    TP        TT    ++S    A S++  TT SP +S    +   SS 
Sbjct: 11495 PAETNTMVPRTTPKFSHSKSDTTLPVAITSPGPEASSAVSTTTISPDMSDLVTSLVPSSG 11554

Query: 1709  ADEATTLGILSGITNRSLSTVNSGTGVALTDTYSRITVPENMLSPTHADSLHTSFNIQVS 1768
              D +TT   LS       +T    T  A T T    T+P      +H  S         +
Sbjct: 11555 TDTSTTFPTLSETPYEPETTATWLTHPAETSTTVSGTIPNF----SHRGS-------DTA 11603

Query: 1769  PSLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLLEKTSLTNYATSLNTPV---SYPPWTP 1825
             PS+ +  S    T++   TT    S    +TS +  +S T+ +T++ T       P  T 
Sbjct: 11604 PSMVT--SPGVDTRSGVPTTTIPPSIPGVVTSQVT-SSATDTSTAIPTLTPSPGEPETTA 11660

Query: 1826  SSATLPSL-TSFVYS----PHSTEAEISTPKTSPPPTSQMVEFPVLGTRMTSSNTQPLLM 1880
             SSAT P   T F       P S    +++  T PP TS  V         +S +  P++ 
Sbjct: 11661 SSATHPGTQTGFTVPIRTVPSSEPDTMASWVTHPPQTSTPVSRTTSSFSHSSPDATPVMA 11720

Query: 1881  TSWNIPTAEGSQFPISTTINVPTSNEMETETLHLVPGPLSTFTASQTGLVSKDVMAMSSI 1940
             TS   P  E S   + TTI+ P + EM T  +        T + + T      +     +
Sbjct: 11721 TS---PRTEASS-AVLTTIS-PGAPEMVTSQI--------TSSGAATSTTVPTLTHSPGM 11767

Query: 1941  PMSGILPNHGLSENPSLSTSLRAITSTL-ADVKHTFEKMTTSVTPGTTLPSILSGATSGS 1999
             P +  L    LS +P   TS     ST+   V  T   +T  + PG    + L   T+ S
Sbjct: 11768 PETTAL----LSTHPRTETSKTFPASTVFPQVSETTASLT--IRPGAETSTALPTQTTSS 11821

Query: 2000  VISKSPILTWLLSSLPSGSPPATVSNAP---HVMTSSTVEVSKSTFLTSDMISAHPFTNL 2056
             + +     T  +   P+ SP  +   AP   H  T ++  +  ST L+  ++       L
Sbjct: 11822 LFTLLVTGTSRVDLSPTASPGVSAKTAPLSTHPGTETSTMIPTST-LSLGLLETTGL--L 11878

Query: 2057  TTLPSATMSTILTRTIPTPTLGGITTG-FPTSLPMSI---NVTDDIVYISTHPEASSRTT 2112
              T  SA  ST       +P + G+++    T  P ++   N        S  P   SRT 
Sbjct: 11879 ATSSSAETSTSTLTLTVSPAVSGLSSASITTDKPQTVTSWNTETSPSVTSVGPPEFSRT- 11937

Query: 2113  ITANPRTVSHPSSFSRKTMSPSTTDHTLSVGAMPLPSSTITSSWNRIPTASSPSTLIIPK 2172
             +T    T+  PS       +P  T H   V    +  +T+  + N   T SSP T+    
Sbjct: 11938 VTGTTMTLI-PSEMP----TPPKTSHGEGVSPTTILRTTMVEATNLATTGSSP-TVAKTT 11991

Query: 2173  PTLDSLLNIMTTTSTVPGASF---------------PLISTGVTYP---FTATVSSPISS 2214
              T ++L   + T  T PG S                  IST  +Y    +T   S+P++S
Sbjct: 11992 TTFNTLAGSLFTPLTTPGMSTLASESVTSRTSYNHRSWISTTSSYNRRYWTPATSTPVTS 12051

Query: 2215  FFETTWLDSTPSFLSTEASTSPTATKSTVSFYNVEMSFSVFVEEPRIPITSVINEFTENS 2274
              F      ST S  S+ A+T P     T++F    + +   +  P     +      +  
Sbjct: 12052 TFSPG--ISTSSIPSSTAATVPFMVPFTLNFTITNLQYEEDMRHPGSRKFNATERELQGL 12109

Query: 2275  LNSIFQNS 2282
             L  +F+NS
Sbjct: 12110 LKPLFRNS 12117



 Score =  199 bits (506), Expect = 4e-50
 Identities = 460/2128 (21%), Positives = 830/2128 (39%), Gaps = 308/2128 (14%)

Query: 231   PENMTIQEKSTTVSQQIDMTTPSQITGVKPQNTAHSSTLLSQSIPIFATDYTTISYSNTT 290
             PE M  Q  S+  S   +++T  + +    ++ + S      +  +  T+  ++  ++T 
Sbjct: 8695  PETMMTQPTSSLTSGLREISTSQETSSATERSASLSGMPTGATTKVSRTEALSLGRTSTP 8754

Query: 291   SPPLETMTAQKILKTLV----DETATFAVDVL----------STSSAISLPTQSISIDNT 336
              P   T++ +   +T+       T T + ++           S+    +L T S +    
Sbjct: 8755  GPAQSTISPEISTETITRISTPLTTTGSAEMTITPKTGHSGASSQGTFTLDTSSRASWPG 8814

Query: 337   TNSMKKTKSP-SSESTKTTKMVEAMA----TEIFQPPTPSNFLSTSRFTKNSVVSTTSAI 391
             T+S    +SP S  +T  ++  E ++      + +   PS+ +S S  T  S + +T + 
Sbjct: 8815  THSAATHRSPHSGMTTPMSRGPEDVSWPSRPSVEKTSPPSSLVSLSAVTSPSPLYSTPSE 8874

Query: 392   KSQSAVTKTTSLFSTI--ESTSMSTTPCLKQKSTNTGALPISTAGQEFIESTAAGTVPWF 449
              S S+  + TSLF+ +  ++T M  T  L+  +T+  ++ I T+ +    S A       
Sbjct: 8875  SSHSSPLRVTSLFTPVMMKTTDMLDTS-LEPVTTSPPSMNI-TSDESLATSKATMETEAI 8932

Query: 450   TVEKTSPASTHVGTAS-------SFP--PEPVLISTAAPVDSVFPRN-QTAFPLATTDMK 499
              + + + A T +GT S       S+P  PEP  +++     S       T  P ++   +
Sbjct: 8933  QLSENT-AVTQMGTISARQEFYSSYPGLPEPSKVTSPVVTSSTIKDIVSTTIPASSEITR 8991

Query: 500   IAFTVHSLTLPTRLIETTPAPRTAETELTSTNFQDVSLPRVEDAMS-------------T 546
             I     S   PT    +T     + T+ ++  ++ ++   +ED+M+             +
Sbjct: 8992  IEMESTSTLTPTPRETSTSQEIHSATKPSTVPYKALTSATIEDSMTQVMSSSRGPSPDQS 9051

Query: 547   SMSKETSSKTFSFLTSFSFTGTESVQTVIDAEATRTALTPEITLASTVAETMLSSTITGR 606
             +MS++ S++  + L++ S   TES +  I  +      T   TL    + T +S T +  
Sbjct: 9052  TMSQDISTEVITRLST-SPIKTESTEMTITTQTGSPGATSRGTLTLDTSTTFMSGTHS-- 9108

Query: 607   VYTQNTPTADGHLLTLMSTRSAS----TSKAPESGPTSTTDEAAHLFSSNETIWTSRPDQ 662
               T +   +   +  LMS         +  + E   +++   ++ + +S+  + ++ PD 
Sbjct: 9109  --TASQGFSHSQMTALMSRTPGDVPWLSHPSVEEASSASFSLSSPVMTSSSPVSSTLPDS 9166

Query: 663   ALLASMNTTTILTFVPNENFTSAFHENTTYTEYLSATTNITPLKASPEGKGTTANDATTA 722
                +S+  T++LT                 T  L  T++     + P    T+A      
Sbjct: 9167  IHSSSLPVTSLLT------------SGLVKTTELLGTSSEPETSSPPNLSSTSAEILAIT 9214

Query: 723   RYTTAVSKL--TSPWFANFSIVSGTTSITNMPEFKLTTLLLKTIPMSTKPANELPLTPRE 780
               TT   KL  T+   + ++  S ++ + +    K T+ +  T P  T   N L  TP  
Sbjct: 9215  EVTTDTEKLEMTNVVTSGYTHESPSSVLADSVTTKATSSMGITYP--TGDTNVLTSTPAF 9272

Query: 781   TVVPSVDIISTLACIQPNFSTEESASETTQTEINGAIVFGGTTTPVPKSATTQRLNATVT 840
             +    +   S L+ + P    E S SE T +    + V       VP  ATT+     V+
Sbjct: 9273  SDTSRIQTKSKLS-LTPGLM-ETSISEETSSATEKSTVLSS----VPTGATTE-----VS 9321

Query: 841   RKEATSHYLMRKSTIAAVAEVSPFSTMLEVTDESAQRVTASVTVSSFPDIEKLSTPLDNK 900
             R EA S     +++I   A+    STM   T              S   I ++STPL  K
Sbjct: 9322  RTEAISS---SRTSIPGPAQ----STMSSDT--------------SMETITRISTPLTRK 9360

Query: 901   TATTEVRESWLLTKLVKTTPRSSYNEMTEMFNFNHTYVAHWTSETSEGISAGSPTSGSTH 960
              +T        +    KT P  + ++ T  F  + +  A W    S        +  +T 
Sbjct: 9361  ESTD-------MAITPKTGPSGATSQGT--FTLDSSSTASWPGTHSATTQRFPQSVVTTP 9411

Query: 961   IFGEPLGASTTRISETSFSTTPTDRTATSLSDGILPPQPTAAHSS-ATPVPVTHMFSLPV 1019
             +   P   S         ++ P+   ++S      P   T + SS ++PVPVT +F+   
Sbjct: 9412  MSRGPEDVSWPSPLSVEKNSPPSSLVSSSSVTSPSPLYSTPSGSSHSSPVPVTSLFT--- 9468

Query: 1020  NGSSVVAEETEVTMS--EPSTLARAFSTSVLSDVSNLSSTTMT-TALVPPLDQTASTTIV 1076
                S++ + T++  +  EP T + A + ++ SD S  +S   T T  +   + TA++ + 
Sbjct: 9469  ---SIMMKATDMLDASLEPETTS-APNMNITSDESLAASKATTETEAIHVFENTAASHVE 9524

Query: 1077  IVPTHGDLIRTTSEATVISVRKTSMAVPSLTETPFHSLRLSTPVTAKAETTLFST-SVDT 1135
                   +L  ++   +      T +  P +T +      +ST +   +  T     S+ +
Sbjct: 9525  TTSATEELYSSSPGFS----EPTKVISPVVTSSSIRDNMVSTTMPGSSGITRIEIESMSS 9580

Query: 1136  VTPSTHTLVCSKPPPDNIPPASSTHVISTTSTPEATQPISQVEETSTYALSFPYTFSGGG 1195
             +TP       S+    +   ++  + + + +TPE ++  ++V  +S  ++  P       
Sbjct: 9581  LTPGLRETRTSQDITSSTETSTVLYKMPSGATPEVSR--TEVMPSSRTSIPGP------- 9631

Query: 1196  VVASLATGTTETSVVDETTPSHISANKLTTSVNSHISSSATYRVHTP-VSIQLVTSTSVL 1254
                  A  T    + DE      ++  +T S    I++   Y + T  V++ L TS + L
Sbjct: 9632  -----AQSTMSLDISDEVVTRLSTSPIMTESAEITITTQTGYSLATSQVTLPLGTSMTFL 9686

Query: 1255  SSDKDQMTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHS 1314
             S     M+  L  +    E+T +          SRG  SL  T   F ETT+ SS  T  
Sbjct: 9687  SGTHSTMSQGLSHS----EMTNLM---------SRGPESLSWTSPRFVETTRSSSSLTSL 9733

Query: 1315  PSEIPLGTPSDGNLASSPTS----------GSTQITPTL-TSSNTVGVHIPEMSTSLGKT 1363
             P    L   S   L SSP+S          G  + T  L TSS       P +S++  + 
Sbjct: 9734  PLTTSLSPVSSTLLDSSPSSPLPVTSLILPGLVKTTEVLDTSSEPKTSSSPNLSSTSVEI 9793

Query: 1364  ALPSQALTITTFLCPEKESTSALPAYTPRTV----EMIVNSTYVTHSVSYGQDTSFVDTT 1419
                S+ +T T  + P   +T+     T  +V      ++  +  T ++     TS VD T
Sbjct: 9794  PATSEIMTDTEKIHP-SSNTAVAKVRTSSSVHESHSSVLADSETTITIPSMGITSAVDDT 9852

Query: 1420  TSSSTRISNPMDINTTFSHLHSLRTQPEVTSVASFISESTQTFPESLSLSTAGLYNDGFT 1479
             T  ++        N  FS    + T+P  +    F   ST     S++ ++A LY     
Sbjct: 9853  TVFTS--------NPAFSETRRIPTEPTFSLTPGFRETSTSEETTSITETSAVLY----- 9899

Query: 1480  VLSDRITTAFSVPNVPTMLPRESSMATSTPIYQMSSLPVNVTAFTSKKVSDTPPIVITKS 1539
                           VPT    E SM        MSS  +++       +S   P +IT+ 
Sbjct: 9900  -------------GVPTSATTEVSMTEI-----MSSNRIHIPDSDQSTMS---PDIITEV 9938

Query: 1540  SKTMHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPATVSSDTSTRVGLFSTLL---SSVT 1596
                +          ++S  MSE + + +     +P   +  T T     + L    S+V 
Sbjct: 9939  ITRL----------SSSSMMSESTQMTITTQKSSPGATAQSTLTLATTTAPLARTHSTVP 9988

Query: 1597  PRTTMTMQTSTLDVTPVIYAGATSKNKMVSSAFTTEMIEAPSRI--TPTTFLSPTEPTLP 1654
             PR   +  T+ +  +P        +N    S+   E   + S +   P T       TLP
Sbjct: 9989  PRFLHSEMTTLMSRSP--------ENPSWKSSLFVEKTSSSSSLLSLPVTTSPSVSSTLP 10040

Query: 1655  FVKTVPTTIMAGIVTPFVGTTAFSPLSSKSTGAISSIPKTTFSPFLSATQQSSQADEATT 1714
               +++P+       + F  T+  +P   K+T   S+ P T+ SP LS T     A    T
Sbjct: 10041 --QSIPS-------SSFSVTSLLTPGMVKTTDT-STEPGTSLSPNLSGTSVEILAASEVT 10090

Query: 1715  LGILSGITNRSLSTVNSGTGVALTDTYSRITVPENMLSPTHADSLHTSFNIQVSPSLTSF 1774
                     + S++  N GT  +  + YS +++        H++    ++ +    S+   
Sbjct: 10091 TDTEKIHPSSSMAVTNVGTTSSGHELYSSVSI--------HSEPSKATYPVGTPSSMAET 10142

Query: 1775  KSASGPTKNVKTTTNCFSSNTRKMTSLLEKTSLTNYATSLNTPVSYPPWTPSSATLPSLT 1834
               ++    N + TT   +     +TS   KT++     SL+T    P  TPSS     L 
Sbjct: 10143 SISTSMPANFE-TTGFEAEPFSHLTSGFRKTNM-----SLDTSSVTPTNTPSSPGSTHLL 10196

Query: 1835  SFVYSPHSTEAEISTPKTSPPPTSQMVEFPVLGTRMTSSNTQPLLMTSWNIPTAEGSQFP 1894
                 +  ++ A+ S+P    PP SQ  E PV    +T  N  P +  S  I +   S+F 
Sbjct: 10197 QSSKTDFTSSAKTSSPDW--PPASQYTEIPV--DIITPFNASPSITESTGITSFPESRFT 10252

Query: 1895  ISTTINVPTSNEMETETLHLVPGPLSTFTASQTGLVSKDVM-AMSSIPMSGILPNHGLSE 1953
             +S T            T HL    L +     TG V   +  AM+S   +G+      S 
Sbjct: 10253 MSVT----------ESTHHLSTDLLPSAETISTGTVMPSLSEAMTSFATTGVPRAISGSG 10302

Query: 1954  NPSLSTSLRAITSTLADVKHT--------FEKMTTSVTPGTTLPSI----LSGATS---- 1997
             +P   T      +TL+ +  +        F   T + T  +T+P++     S AT     
Sbjct: 10303 SPFSRTESGPGDATLSTIAESLPSSTPVPFSSSTFTTTDSSTIPALHEITSSSATPYRVD 10362

Query: 1998  ---GSVISKSPILTWLLSSLPSGSPPATVSNAPHVMTSSTVEVSKSTFLTSDMISAHPFT 2054
                G+  S +     ++S+L + S P   S++P + T  T  V   T     + SA+   
Sbjct: 10363 TSLGTESSTTEGRLVMVSTLDTSSQPGRTSSSPILDTRMTESVELGT-----VTSAYQVP 10417

Query: 2055  NLTTLPSATMSTILTRTIPTPTLGGITTGFPTSLPMSINVTDDIVYISTHPEASSRTTIT 2114
             +L+T  + T   +   T          T  P   P +         + T       TT T
Sbjct: 10418 SLSTRLTRTDGIMEHITKIPNEAAHRGTIRPVKGPQTSTSPASPKGLHTGGTKRMETTTT 10477

Query: 2115  ANPRTVSHPSSFSRKTMSPSTTDHTLSVGAMPLPSSTITSSWNRIPTASSPSTLI----I 2170
             A   T +   + SR T++ S    TL     PL +S   +S   IPT    +T      +
Sbjct: 10478 ALKTTTTALKTTSRATLTTSVYTPTLGT-LTPLNASMQMAS--TIPTEMMITTPYVFPDV 10534

Query: 2171  PKPTLDSLLNIMTTTSTVPGASFPLISTGVTYPFTATVS------SPISSFFE--TTWLD 2222
             P+ T     ++   TST    + P +    +    + VS      SP+    +  ++  D
Sbjct: 10535 PETTSSLATSLGAETSTALPRTTPSVFNRESETTASLVSRSGAERSPVIQTLDVSSSEPD 10594

Query: 2223  STPSFLSTEASTSPTATKSTVSFYNVEM 2250
             +T S++   A T PT +K+T +F++ E+
Sbjct: 10595 TTASWVIHPAETIPTVSKTTPNFFHSEL 10622



 Score =  189 bits (480), Expect = 4e-47
 Identities = 535/2325 (23%), Positives = 900/2325 (38%), Gaps = 428/2325 (18%)

Query: 285  SYSNTTSPPLETMTAQKILKTLVDETATFAVDVLSTSSAISLPTQSISIDNTTNSMKKTK 344
            S S++ SPPL   T     KT+  +T    V  L     ++L T +I+            
Sbjct: 6138 SSSHSNSPPLTISTH----KTIATQTGPSGVTSLGQ---LTLDTSTIAT----------- 6179

Query: 345  SPSSESTKTTKMVEAMATEIFQPPTPSNFLSTSRFTKNSVVSTTS-----AIKSQSAVTK 399
            S  + S +T   V++  T +      ++ L TS F+     S +S        S S VT 
Sbjct: 6180 SAGTPSARTQDFVDSETTSVMNNDL-NDVLKTSPFSAEEANSLSSQAPLLVTTSPSPVTS 6238

Query: 400  TTSLFST---IESTSMSTTPCLKQKSTNTGALPISTAGQEFIES--TAAGTVPWFTVEKT 454
            T    ST   +  TS+ T    K    +T   P++ + Q    +  T+  T    T+  +
Sbjct: 6239 TLQEHSTSSLVSVTSVPTPTLAKITDMDTNLEPVTRSPQNLRNTLATSEATTDTHTMHPS 6298

Query: 455  -SPASTHVGTASS--------------FPPEPVLISTAAPVDSVFPRNQTAFPLATTDMK 499
             + A  +VGT SS              +     ++ T+   DS+     T+ P ++   K
Sbjct: 6299 INTAVANVGTTSSPNEFYFTVSPDSDPYKATSAVVITSTSGDSIV---STSMPRSSAMKK 6355

Query: 500  IAFTVHSLTLPTRLIETTPAPR----------------TAETELTSTNFQDVSLPRVEDA 543
            I     + +L  RL ET+ + +                 A TE++ T     S   ++  
Sbjct: 6356 IESET-TFSLIFRLRETSTSQKIGSSSDTSTVFDKAFTAATTEVSRTELTSSSRTSIQGT 6414

Query: 544  MSTSMSKETSSKTFSFLTSF-----SFTGTESVQTVIDAEATRTALTPEITLASTVAETM 598
               +MS +TS+++ + L++F     S   T + QT      ++  LT + ++ ++ A T 
Sbjct: 6415 EKPTMSPDTSTRSVTMLSTFAGLTKSEERTIATQTGPHRATSQGTLTWDTSITTSQAGTH 6474

Query: 599  LS----------STITGRVYTQNTPTADGHLLTLMSTRS-------ASTSKAPESGPTST 641
             +          ST+T RV    + T+   +    S+ S        S S  P + P S 
Sbjct: 6475 SAMTHGFSQLDLSTLTSRVPEYISGTSPPSVEKTSSSSSLLSLPAITSPSPVPTTLPESR 6534

Query: 642  TDEAAHLFSSNETIWTSRPDQALLASMNTTTILTFVPNENFTSAFHENTTYTEYLSATTN 701
                 HL        TS P   L+ + +    +  +P  N  S  H+  T +E +  T  
Sbjct: 6535 PSSPVHL--------TSLPTSGLVKTTDMLASVASLP-PNLGSTSHKIPTTSEDIKDTEK 6585

Query: 702  ITP-LKASPEGKGTTANDATTARYTTAVS---KLTSPWFANFSIVSGTTSITNMPEFKLT 757
            + P    +    GTT ++  +     A S   K+TSP   +F+I     S T+MP     
Sbjct: 6586 MYPSTNIAVTNVGTTTSEKESYSSVPAYSEPPKVTSPMVTSFNIRDTIVS-TSMPGSSEI 6644

Query: 758  TLLLKTIPMSTKPANELPLTPRETVVPSVDIISTLACIQPNFSTEESASETTQTEINGAI 817
            T +      S     +   T ++ +V +       + +    +T   A+ET++TE+  + 
Sbjct: 6645 TRIEMESTFSLAHGLKGTSTSQDPIVSTEK-----SAVLHKLTT--GATETSRTEVASS- 6696

Query: 818  VFGGTTTPVPKSAT-TQRLNATVTRKEATSHYLMRKSTIAAVAEVSP-------FSTMLE 869
                T+ P P  +T +  ++  V      S  +   S +  +    P        +  L+
Sbjct: 6697 --RRTSIPGPDHSTESPDISTEVIPSLPISLGITESSNMTIITRTGPPLGSTSQGTFTLD 6754

Query: 870  VTDESAQRVTASVTVSSFP----------DIEKLSTPLDNKTATTEVRESWLLTKLVKTT 919
                S++  T S+    FP          D E LS  +      T    S + +  + + 
Sbjct: 6755 TPTTSSRAGTHSMATQEFPHSEMTTVMNKDPEILSWTIPPSIEKTSFSSSLMPSPAMTSP 6814

Query: 920  PRSSYNEMTEMFNFNHTYVAHWTSETSEGISAGSPTSGSTHIFGEPLGASTTRISETSFS 979
            P SS    T      HT  +  TS  +  +   + T G++    EP  +S   +S TS  
Sbjct: 6815 PVSSTLPKTI-----HTTPSPMTSLLTPSLVMTTDTLGTSP---EPTTSSPPNLSSTSHE 6866

Query: 980  TTPTDRTATSLSDGILPPQPTAAHSSATPVPVTHMFSLPVNGSSVVAEETEVTMSEP-ST 1038
               TD   T++ + + P   TAA    T V  T   S   + SSV+A+  +   + P  T
Sbjct: 6867 ILTTDEDTTAI-EAMHPSTSTAA----TNVETTS--SGHGSQSSVLADSEKTKATAPMDT 6919

Query: 1039 LARAFSTSVLSDVSNLSSTTM-----TTALVPPLDQTA---------STTIVI--VPTH- 1081
             +    T+V + +S  S TT      T +L P L +T+          T+IV+  VPT  
Sbjct: 6920 TSTMGHTTVSTSMSVSSETTKIKRESTYSLTPGLRETSISQNASFSTDTSIVLSEVPTGT 6979

Query: 1082 -GDLIRT---TSEATVISVRKTSMAVPSLTETPFHSLRLSTPVTAKAETTL-------FS 1130
              ++ RT   +S  T I     S  +P ++      L  S  +T  AE T+        S
Sbjct: 6980 TAEVSRTEVTSSGRTSIPGPSQSTVLPEISTRTMTRLFASPTMTESAEMTIPTQTGPSGS 7039

Query: 1131 TSVDTVT---------PSTHTLVCSKPPPDNIPPASSTHV--ISTTSTPEATQP------ 1173
            TS DT+T           TH+ +  + P   +    S     +S  S+P    P      
Sbjct: 7040 TSQDTLTLDTSTTKSQAKTHSTLTQRFPHSEMTTLMSRGPGDMSWQSSPSLENPSSLPSL 7099

Query: 1174 ISQVEETSTYALS--FPYTFSGGGV-VASLATGT---------TETSVVDETTP--SHIS 1219
            +S    TS   +S   P T S   + V SL T +         T   +V  + P  SH S
Sbjct: 7100 LSLPATTSPPPISSTLPVTISSSPLPVTSLLTSSPVTTTDMLHTSPELVTSSPPKLSHTS 7159

Query: 1220 ANKLTTSVNS------HISSS-ATYRVHTPVSIQLVTSTSVLSSDKDQMTISLGKTPRTM 1272
              +LTT  ++      H S++ A   V  P S     S+++  S+  + T  +  T  T 
Sbjct: 7160 DERLTTGKDTTNTEAVHPSTNTAASNVEIPSSGHESPSSALADSETSKATSPMFITS-TQ 7218

Query: 1273 EVTEMSPSKNSFISYSR------GTPSLEMTDTGFPETTKISSHQTHSPSEIPLGTPSDG 1326
            E T ++ S   F+  SR       + S ++ +TG    T  +   +   SE+ +G  ++ 
Sbjct: 7219 EDTTVAISTPHFLETSRIQKESISSLSPKLRETGSSVETSSAIETSAVLSEVSIGATTEI 7278

Query: 1327 NLASSPTSGSTQITPTLTSSNTVGVHIPEMSTSLGKTALP-------SQALTITTFLCPE 1379
            +     +S  T I+ +  S+      +PE+ST+      P       S  +TI T   P 
Sbjct: 7279 SRTEVTSSSRTSISGSAESTM-----LPEISTTRKIIKFPTSPILAESSEMTIKTQTSPP 7333

Query: 1380 -KESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSSTRISN-PMDINTTFS 1437
               S S     T  T  +++  + +T  + + + T+ V        R S+ P++  +  S
Sbjct: 7334 GSTSESTFTLDTSTTPSLVITHSTMTQRLPHSEITTLVSRGAGDVPRPSSLPVEETSPPS 7393

Query: 1438 HLHSLRTQPEVTSVASFISESTQTFPESLSLSTAGLYNDGFTVLSDRITTAFSVPNVPTM 1497
               SL      + V+S +  S+     S S S   L   G  V +  +  A + P     
Sbjct: 7394 SQLSLSAMISPSPVSSTLPASSH----SSSASVTSLLTPG-QVKTTEVLDASAEPE---- 7444

Query: 1498 LPRESSMATSTPIYQMSSLPVNVTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTATSG 1557
                    TS+P   +SS  V + A TS+  +DT  I    ++     G      T++SG
Sbjct: 7445 --------TSSPP-SLSSTSVEILA-TSEVTTDTEKIHPFSNTAVTKVG------TSSSG 7488

Query: 1558 PMSEMSSIPVNNSAFTPATVSSDTSTRVGLFSTLLSSVTPR---------------TTMT 1602
              S  S +P  +S  T AT +  T + +G   T +S++TP                TT  
Sbjct: 7489 HESPSSVLP--DSETTKATSAMGTISIMG--DTSVSTLTPALSNTRKIQSEPASSLTTRL 7544

Query: 1603 MQTSTLDVTPVIYAGATSKNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTLPFVKTVPTT 1662
             +TST + T +     T  +K VS+  TTE+    SR    +F S T  + P   T+   
Sbjct: 7545 RETSTSEETSLATEANTVLSK-VSTGATTEV----SRTEAISF-SRTSMSGPEQSTMSQD 7598

Query: 1663 IMAGIVTPFVGTTAFSPLSSKSTGAISSIP-KTTFSPFLSATQQSSQADEATTLGILSGI 1721
            I  G + P +  ++    S+K T    + P ++T    L+    ++ +   T   ++ G 
Sbjct: 7599 ISIGTI-PRISASSVLTESAKMTITTQTGPSESTLESTLNLNTATTPSWVETHSIVIQGF 7657

Query: 1722 TNRSLST-VNSGTGVALTDT---YSRITVPENMLSPTHADSLH---TSFNIQVSPSLTSF 1774
             +  ++T +  G G     +       + P + LS     S H   T+F   + PS    
Sbjct: 7658 PHPEMTTSMGRGPGGVSWPSPPFVKETSPPSSPLSLPAVTSPHPVSTTFLAHIPPSPLPV 7717

Query: 1775 KS--ASGPTKNVKTTTNCFSSNTRKMTSLLEKTS------LTNYATSLNTPVSYPPWTPS 1826
             S   SGP     TTT+   ++T   TS     S      LT Y  + +T   +P  T +
Sbjct: 7718 TSLLTSGPA----TTTDILGTSTEPGTSSSSSLSTTSHERLTTYKDTAHTEAVHPS-TNT 7772

Query: 1827 SATLPSLTSFVYSPHSTEAEISTPKTSPPP---TSQMVEFPV------LGTRMTSSNTQP 1877
              T  + TS  Y   S+    S+P  +      TS +   P       + T + SS T  
Sbjct: 7773 GGTNVATTSSGYKSQSSVLADSSPMCTTSTMGDTSVLTSTPAFLETRRIQTELASSLTPG 7832

Query: 1878 LLMTSWNIPTAEGSQFPISTTIN-VPT--SNEMETETLHLVPGP-------------LST 1921
            L  +S +  T+ G++  +ST ++ VPT  + E+  E +  +PGP             +S 
Sbjct: 7833 LRESSGSEGTSSGTK--MSTVLSKVPTGATTEISKEDVTSIPGPAQSTISPDISTRTVSW 7890

Query: 1922 FTASQTGLVSKDVMAMSSIPMSGILPNHGLSENPSLSTSLRAITSTLAD----------- 1970
            F+ S     S ++   +     G       + + S +TSL    ST++            
Sbjct: 7891 FSTSPVMTESAEITMNTHTSPLGATTQGTSTLDTSSTTSLTMTHSTISQGFSHSQMSTLM 7950

Query: 1971 --------------VKHTFEKMTTSVTPGTTLPSILSGATSGSVISKSPILTWLLSS--- 2013
                          ++ T    +   +P TT PS +S     S+ S    +T LL+S   
Sbjct: 7951 RRGPEDVSWMSPPLLEKTRPSFSLMSSPATTSPSPVSSTLPESISSSPLPVTSLLTSGLA 8010

Query: 2014 -----LPSGSPPATVSNAPHVMTSSTVEVSKSTFLTSDMISAHPFTNLTTLPSATMST-- 2066
                 L   S P T  N+P  ++S++VE+  ++ +T+D    HP +N T     T S+  
Sbjct: 8011 KTTDMLHKSSEPVT--NSPANLSSTSVEILATSEVTTDTEKTHPSSNRTVTDVGTSSSGH 8068

Query: 2067 -------------------ILTRTIPTPTLGGITTGF---------PT-SLPMSINVTDD 2097
                               ++T T+   ++   T GF         PT SL + +  T  
Sbjct: 8069 ESTSFVLADSQTSKVTSPMVITSTMEDTSVSTSTPGFFETSRIQTEPTSSLTLGLRKTSS 8128

Query: 2098 IVYISTHPEAS--------------SRTTITANPRTVSHPSSFSRKTMSPSTTDHTLSVG 2143
                S   E S              SRT +T++ RT    S F++ T+SP T+  T++  
Sbjct: 8129 SEGTSLATEMSTVLSGVPTGATAEVSRTEVTSSSRT--SISGFAQLTVSPETSTETIT-- 8184

Query: 2144 AMPLPSSTITSSWNRIPTASSPSTLIIPKPT----LDSLLNIMTTTSTVPGASFPLISTG 2199
             +P  S    S+   I T + P     P+ T    + +  N + T STV         T 
Sbjct: 8185 RLPTSSIMTESAEMMIKTQTDPPG-STPESTHTVDISTTPNWVETHSTVTQRFSHSEMTT 8243

Query: 2200 VTYPFTATVSSPISSFFETTWLDSTPSFLSTEASTSPTATKSTV--SFYNVEMSFSVFVE 2257
            +       +  P  S  E T   S  S LS  A+TSP+   ST+   F +  +  +  + 
Sbjct: 8244 LVSRSPGDMLWPSQSSVEET--SSASSLLSLPATTSPSPVSSTLVEDFPSASLPVTSLL- 8300

Query: 2258 EPRIPITS----VINEFTENSLNSIFQNSEFSLATLETQIKSRDI 2298
             P + IT+    +  E   +S +++   S   L TLE  + + D+
Sbjct: 8301 NPGLVITTDRMGISREPGTSSTSNLSSTSHERLTTLEDTVDTEDM 8345



 Score =  186 bits (473), Expect = 2e-46
 Identities = 506/2297 (22%), Positives = 880/2297 (38%), Gaps = 406/2297 (17%)

Query: 231   PENMTIQEKS--TTVSQQIDMTTPSQITGVKPQNTAHSS----TLLSQSIPIFATDYTTI 284
             P  +++++ S  +++     +T+PS +    P  ++HSS    T L  SI + ATD    
Sbjct: 9422  PSPLSVEKNSPPSSLVSSSSVTSPSPLYST-PSGSSHSSPVPVTSLFTSIMMKATDMLDA 9480

Query: 285   SYS-NTTSPPLETMTAQKILKTLVDETATFAVDVL------------------STSSAIS 325
             S    TTS P   +T+ + L      T T A+ V                   S+S   S
Sbjct: 9481  SLEPETTSAPNMNITSDESLAASKATTETEAIHVFENTAASHVETTSATEELYSSSPGFS 9540

Query: 326   LPTQSISIDNTTNSMK--------------------------------KTKSPSSESTKT 353
              PT+ IS   T++S++                                +T    + ST+T
Sbjct: 9541  EPTKVISPVVTSSSIRDNMVSTTMPGSSGITRIEIESMSSLTPGLRETRTSQDITSSTET 9600

Query: 354   TKMV---------EAMATEIFQPPTPSNFLSTSRFTKNSVVS-------TTSAIKSQSAV 397
             + ++         E   TE+  P + ++    ++ T +  +S       +TS I ++SA 
Sbjct: 9601  STVLYKMPSGATPEVSRTEVM-PSSRTSIPGPAQSTMSLDISDEVVTRLSTSPIMTESAE 9659

Query: 398   TKTTSLFSTIESTSMSTTPCLKQKSTNTGALPISTAGQEFIESTAAGTVPWFTVEKTSPA 457
                T+      +TS  T P     +  +G     + G    E T   +    ++  TSP 
Sbjct: 9660  ITITTQTGYSLATSQVTLPLGTSMTFLSGTHSTMSQGLSHSEMTNLMSRGPESLSWTSPR 9719

Query: 458   STHVGTASSFPPEPVLISTAAPVDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETT 517
                   +SS      L ++ +PV S    +  + PL  T + +      L   T +++T+
Sbjct: 9720  FVETTRSSSSLTSLPLTTSLSPVSSTLLDSSPSSPLPVTSLILP----GLVKTTEVLDTS 9775

Query: 518   PAPRTAET-ELTSTNFQDVSLPRVEDAMSTSMSKETSSKTFSFLTSFSFTGTESVQTVID 576
               P+T+ +  L+ST+   V +P   + M+ +     SS T       S +  ES  +V+ 
Sbjct: 9776  SEPKTSSSPNLSSTS---VEIPATSEIMTDTEKIHPSSNTAVAKVRTSSSVHESHSSVL- 9831

Query: 577   AEATRTALTPEITLASTVAETMLSSTITGRVYTQNTPTADGHLLTL----MSTRSASTSK 632
             A++  T   P + + S V +T + ++      T+  PT     LT      ST   +TS 
Sbjct: 9832  ADSETTITIPSMGITSAVDDTTVFTSNPAFSETRRIPTEPTFSLTPGFRETSTSEETTSI 9891

Query: 633   APESG-----PTSTTDEAA--HLFSSNETIWTSRPDQALLASMNTTTILTFVPNENFTSA 685
                S      PTS T E +   + SSN  I     DQ+ ++    T ++T + + +  S 
Sbjct: 9892  TETSAVLYGVPTSATTEVSMTEIMSSNR-IHIPDSDQSTMSPDIITEVITRLSSSSMMS- 9949

Query: 686   FHENTTYTEYLSATTNITPLKASPEGKGTTANDATTARYTTAVSKLTS----PWFANFSI 741
               E+T  T        IT  K+SP   G TA    T   TTA    T     P F +  +
Sbjct: 9950  --ESTQMT--------ITTQKSSP---GATAQSTLTLATTTAPLARTHSTVPPRFLHSEM 9996

Query: 742   VSGTTSITNMPEFKLTTLLLKTIPMSTKPANELPLTPRETVVPSVDIISTLACIQPNFST 801
              +  +     P +K +  + KT   S+     LP+T      PSV   STL    P    
Sbjct: 9997  TTLMSRSPENPSWKSSLFVEKT--SSSSSLLSLPVTTS----PSVS--STLPQSIP---- 10044

Query: 802   EESASETTQTEINGAIVFGGTTTPVPKSATTQRLNATVTRKEATSHYLMRKSTIAAVAEV 861
               S+S +  + +   +V    T+  P ++ +  L+ T     A S             ++
Sbjct: 10045 --SSSFSVTSLLTPGMVKTTDTSTEPGTSLSPNLSGTSVEILAASE------VTTDTEKI 10096

Query: 862   SPFSTMLEV---TDESAQRVTASVTVSSFPDIEKLSTPLDNKTATTEVRESWLLTKLVKT 918
              P S+M      T  S   + +SV++ S P   K + P+   ++  E   S  +    +T
Sbjct: 10097 HPSSSMAVTNVGTTSSGHELYSSVSIHSEPS--KATYPVGTPSSMAETSISTSMPANFET 10154

Query: 919   T--PRSSYNEMTEMFNFNHTYVAHWTSETSEGISAGSPTSGSTHIFGEPLGASTTRISET 976
             T      ++ +T    F  T ++  TS  +   +  SP  GSTH+               
Sbjct: 10155 TGFEAEPFSHLTS--GFRKTNMSLDTSSVTPTNTPSSP--GSTHLL-------------- 10196

Query: 977   SFSTTPTDRTATSLSDGILPPQPTAAHSSATPVPVTHMFSLPVNGSSVVAEETEVTMSEP 1036
                ++ TD T+++ +    P  P A+  +  PV +      P N S  + E T +T    
Sbjct: 10197 --QSSKTDFTSSAKTSS--PDWPPASQYTEIPVDII----TPFNASPSITESTGITSFPE 10248

Query: 1037  STLARA-------FSTSVLSDVSNLSSTTMTTALVPPLDQTASTTI--VIVPTHGDLIRT 1087
             S    +        ST +L     +S+ T+  +L   +   A+T +   I  +     RT
Sbjct: 10249 SRFTMSVTESTHHLSTDLLPSAETISTGTVMPSLSEAMTSFATTGVPRAISGSGSPFSRT 10308

Query: 1088  TSEATVISVRKTSMAVPSLTETPFHSLRLSTPVTAKAETTLFSTSVDTVTPSTHTLVCSK 1147
              S     ++   + ++PS T  PF S             + F+T+  +  P+ H +  S 
Sbjct: 10309 ESGPGDATLSTIAESLPSSTPVPFSS-------------STFTTTDSSTIPALHEITSSS 10355

Query: 1148  PPPDNIPPASSTHVISTTSTPEATQPISQVEETSTYALSFPYTFSGGGVVASLATGTTET 1207
               P  +  +  T     +ST E    +    +TS    S P   S   ++ +  T + E 
Sbjct: 10356 ATPYRVDTSLGTE----SSTTEGRLVMVSTLDTS----SQPGRTSSSPILDTRMTESVEL 10407

Query: 1208  SVVDET--TPSHISANKLTTSVNSHISSSATYRVHTPVSIQLVTSTSVLSSDKDQMTISL 1265
               V      PS  +    T  +  HI+       H                   + TI  
Sbjct: 10408 GTVTSAYQVPSLSTRLTRTDGIMEHITKIPNEAAH-------------------RGTIRP 10448

Query: 1266  GKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSPSEIPLGTPSD 1325
              K P+T      SP+    + ++ GT  +E T T    TT      + +     + TP+ 
Sbjct: 10449 VKGPQT----STSPASPKGL-HTGGTKRMETTTTALKTTTTALKTTSRATLTTSVYTPTL 10503

Query: 1326  GNLASSPTSGSTQITPTLTSSNTVGV-----HIPE----MSTSLGKTALPSQALTITTFL 1376
             G L  +P + S Q+  T+ +   +        +PE    ++TSLG     +   T  +  
Sbjct: 10504 GTL--TPLNASMQMASTIPTEMMITTPYVFPDVPETTSSLATSLGAETSTALPRTTPSVF 10561

Query: 1377  CPEKESTSALPAYTPRTVEMIVNSTYVTHS--------VSYGQDT-------------SF 1415
               E E+T++L + +      ++ +  V+ S        V +  +T             S 
Sbjct: 10562 NRESETTASLVSRSGAERSPVIQTLDVSSSEPDTTASWVIHPAETIPTVSKTTPNFFHSE 10621

Query: 1416  VDTTTSSSTR----ISNPMDINTTFSHLHSLRTQPEVTSVASFISESTQTFPESLSLSTA 1471
             +DT +S++T     +S+ +  N + S L +L     ++      ++++ TFP   +L+ +
Sbjct: 10622 LDTVSSTATSHGADVSSAIPTNISPSELDALTPLVTISG-----TDTSTTFP---TLTKS 10673

Query: 1472  GLYNDGFTV-LSDRITTAFSVPN-VPTMLPRES----SMATSTPIYQMSSLPVNVTA--- 1522
                 +  T  L+    T+ ++P  +P     ES    S+ATS      S++P+   +   
Sbjct: 10674 PHETETRTTWLTHPAETSSTIPRTIPNFSHHESDATPSIATSPGAETSSAIPIMTVSPGA 10733

Query: 1523  ---FTSKKVSDTPPIVITKSSKTMHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPAT--- 1576
                 TS+  S      +T  + T+ PG  K+  +  + P ++ SS  +  S  +PA    
Sbjct: 10734 EDLVTSQVTSSGTDRNMTIPTLTLSPGEPKTIASLVTHPEAQTSSA-IPTSTISPAVSRL 10792

Query: 1577  VSSDTSTRVGLFSTLLSSVT-----PRTTMTMQTSTLDVTPVIYAGAT----SKNKMVSS 1627
             V+S  ++     ST   ++T     P TT+++ T     +P +    +    SK+    S
Sbjct: 10793 VTSMVTSLAAKTSTTNRALTNSPGEPATTVSLVTHPAQTSPTVPWTTSIFFHSKSDTTPS 10852

Query: 1628  AFTTEMIEAPSRI-TPTTFLSPTEPTLPFVKT----VPTTIMAGIVTPFVGTTAFSPLSS 1682
               T+   E+ S + TPT          P V +    + TTI    ++P    T  S  +S
Sbjct: 10853 MTTSHGAESSSAVPTPTVSTEVPGVVTPLVTSSRAVISTTIPILTLSPGEPETTPSMATS 10912

Query: 1683  KSTGAISSIPKTTFSP----FLSATQQSSQADEATTLGILSGITNRSLSTVNSGTG---- 1734
                 A S+IP  T SP     +++   SS+A  +TT+ IL+       +T +  T     
Sbjct: 10913 HGEEASSAIPTPTVSPGVPGVVTSLVTSSRAVTSTTIPILTFSLGEPETTPSMATSHGTE 10972

Query: 1735  -------------------VALTDTYSRITVPENMLSPTHAD---SLHTSFNIQ------ 1766
                                VA +   +  T+P   LSP   +   S+ TS   +      
Sbjct: 10973 AGSAVPTVLPEVPGMVTSLVASSRAVTSTTLPTLTLSPGEPETTPSMATSHGAEASSTVP 11032

Query: 1767  -VSP-----------SLTSFKSASGPTK-----NVKTTTNCFSSNTRKMTSLLEKTSLTN 1809
              VSP           S +   S S PT       ++TT +  +S+  + +S +   +++ 
Sbjct: 11033 TVSPEVPGVVTSLVTSSSGVNSTSIPTLILSPGELETTPSMATSHGAEASSAVPTPTVSP 11092

Query: 1810  YATSLNTPVSYPPWTPSSATLPSLTSFVYSPHSTEAEISTPKTSPPPTSQMVEFPVLGTR 1869
               + + TP+       +S T+P LT     P +T + ++T       ++ +   P +   
Sbjct: 11093 GVSGVVTPLVTSSRAVTSTTIPILTLSSSEPETTPS-MATSHGVEASSAVLTVSPEVPGM 11151

Query: 1870  MTSSNTQPLLMTSWNIPTAEGSQFPISTTINVPTSNEME----------TETLHLVPGPL 1919
             +TS  T    +TS  IPT   S     TT ++ T +E +          + T+  +   L
Sbjct: 11152 VTSLVTSSRAVTSTTIPTLTISSDEPETTTSLVTHSEAKMISAIPTLAVSPTVQGLVTSL 11211

Query: 1920  STFTASQTGLVSKDVMAMSSIPMSGILPNHGLSENPSLSTSLRAIT----STLADVKHTF 1975
              T + S+T   S   +A S          H  +E  S+  +L   T    + ++ V H  
Sbjct: 11212 VTSSGSETSAFSNLTVASSQPETIDSWVAHPGTEASSVVPTLTVSTGEPFTNISLVTHPA 11271

Query: 1976  EKMTT--------SVTPGTTLPSILSG--ATSGSVISK--SPILTWLLSSLPSGSPPATV 2023
             E  +T        S +   T+PS ++   A S S IS   SP +  +L+SL + S     
Sbjct: 11272 ESSSTLPRTTSRFSHSELDTMPSTVTSPEAESSSAISTTISPGIPGVLTSLVTSSGRDIS 11331

Query: 2024  SNAPHVMTSSTVEVSKSTFLTSDMISAHPFTNLTTLPSATMSTILTRTIPTPTLGGITTG 2083
             +  P V  S     + ++++T      HP    TT+P  T +   +    TP++      
Sbjct: 11332 ATFPTVPESPHESEATASWVT------HPAVTSTTVPRTTPNYSHSEPDTTPSIATSPGA 11385

Query: 2084  FPTSLPMSINVTDDIVYISTHPEASSRT-------TIT---ANPRTVSHPSSFSRKTMSP 2133
               TS   +I V+ D+  + T    SS T       T+T     P T +   ++S    S 
Sbjct: 11386 EATSDFPTITVSPDVPDMVTSQVTSSGTDTSITIPTLTLSSGEPETTTSFITYSETHTSS 11445

Query: 2134  STTDHTLSVGAMPLPSSTITSSWNRIPTA--SSPSTLIIPKPTLDSLLNIMTTTSTVPGA 2191
             +     +S GA  + +S + SS     T   +   T   P+ T   L++   T + VP  
Sbjct: 11446 AIPTLPVSPGASKMLTSLVISSGTDSTTTFPTLTETPYEPETTAIQLIHPAETNTMVPRT 11505

Query: 2192  S--FPLISTGVTYPFTATVSSP-ISSFFETTWLDSTPSFLSTEASTSPTATKSTVSFYNV 2248
             +  F    +  T P   T   P  SS   TT +    S L T    S     ST      
Sbjct: 11506 TPKFSHSKSDTTLPVAITSPGPEASSAVSTTTISPDMSDLVTSLVPSSGTDTST------ 11559

Query: 2249  EMSFSVFVEEPRIPITS 2265
               +F    E P  P T+
Sbjct: 11560 --TFPTLSETPYEPETT 11574



 Score =  183 bits (465), Expect = 2e-45
 Identities = 512/2231 (22%), Positives = 848/2231 (38%), Gaps = 379/2231 (16%)

Query: 275  PIFATDYTTI---SYSNTTSPPLETMTAQKILKTLVDETATFAVDVLSTSSAISLPTQSI 331
            P  +T  TT+   S S TT  P   M+      T   E  T + +  ST S+ +  + S 
Sbjct: 3536 PGISTTITTMGTNSISTTTPNPEVGMSTMD--STPATERRTTSTEHPSTWSSTAA-SDSW 3592

Query: 332  SIDNTTNSMKKTKSPSSESTKTTKMVEAMATEIFQPPTPSNFLSTSRFTKNSVVSTTSAI 391
            ++ + T+++K  +SP + ST  T    A +TE+    TP   ++    +  +  S  SA+
Sbjct: 3593 TVTDMTSNLKVARSPGTISTMHTTSFLASSTELDSMSTPHGRITVIGTSLVTPSSDASAV 3652

Query: 392  KSQSAVT-KTTSLFSTIESTSMSTTPCLKQKSTNTGALPISTAGQEFIESTAAGTVPWFT 450
            K++++ + +T S   T  ST +ST   +++ S +   + +ST+      ST A  VP  +
Sbjct: 3653 KTETSTSERTLSPSDTTASTPISTFSRVQRMSISVPDI-LSTSWTP--SSTEAEDVP-VS 3708

Query: 451  VEKTSPASTHVGTASSFPPEPVLISTAAPVDSVFPRNQTAFPLATTDMKIAFTVHSLTLP 510
            +  T  AST   T  + P    L  + + +D    R+ ++    T+  + A T   LTL 
Sbjct: 3709 MVSTDHASTK--TDPNTPLSTFLFDSLSTLDWDTGRSLSSATATTSAPQGATTPQELTL- 3765

Query: 511  TRLIETTPAPRTAETELTSTNFQDVSLPRVEDAMSTSMSKETSSKTFSFLTSFSFTGTES 570
                ET  +P T++           S+  +  A++ +    +S  TFS            
Sbjct: 3766 ----ETMISPATSQLPF--------SIGHITSAVTPAAMARSSGVTFS----------RP 3803

Query: 571  VQTVIDAEATRTALTPEITLASTVAETMLSSTITGRVYTQNTPTA----DGHLLTLMSTR 626
              T   AE T T L    +          ++T+    +T  TP A     G        R
Sbjct: 3804 DPTSKKAEQTSTQLPTTTSAHPGQVPRSAATTLDVIPHTAKTPDATFQRQGQTALTTEAR 3863

Query: 627  SASTSKAPESGPTSTTDEAAHLFS--SNETIWTSRPDQALLASMNTTTI---LTFVPNEN 681
            + S S   +   T +      + +  S +TI       ++L ++NT  I        + +
Sbjct: 3864 ATSDSWNEKEKSTPSAPWITEMMNSVSEDTIKEVTSSSSVLRTLNTLDINLESGTTSSPS 3923

Query: 682  FTSAFHENTTYTEYLSATTNITPLKASPEGKGTTANDATTARYT----TAVSKLTSPWFA 737
            + S+ +E    +E  +    I P   + E  G   +    +  T    +A SKLTSP   
Sbjct: 3924 WKSSPYERIAPSESTTDKEAIHPSTNTVETTGWVTSSEHASHSTIPAHSASSKLTSP--- 3980

Query: 738  NFSIVSGTTSITNMPEFKLTTLLLKTIPMSTKPANELPLTPRETVVPSVDIISTLACIQP 797
                       T+  E  + ++   T P ST+   E          P+  +   L  + P
Sbjct: 3981 --------VVTTSTREQAIVSMSTTTWPESTRARTE----------PNSFLTIELRDVSP 4022

Query: 798  NFSTEESASETTQTEINGAIVFGGTTTPVPKSATTQRLNATVTRKEATSHYLMRK----- 852
               T    S TTQT    +I+    +T + K   T+      + K  +S +L +      
Sbjct: 4023 YMDT----SSTTQT----SIISSPGSTAITKGPRTE----ITSSKRISSSFLAQSMRSSD 4070

Query: 853  STIAAVAEVSPFSTMLEVTDESAQRVTASVTVSSFPDIEKLSTPLDNKTATTEVRESWLL 912
            S   A+  +S F  M     ES   + A  T  S P    LS P    T  T    SW  
Sbjct: 4071 SPSEAITRLSNFPAM----TESGGMILAMQT--SPPGATSLSAP----TLDTSATASWTG 4120

Query: 913  TKLVKTTPRSSYNEMTEMFNFNHTYVAHWTSETSEGISAGSPTSGSTHIFGEPLGASTTR 972
            T L  TT R +Y+E T +F           S+  E  S  SP S                
Sbjct: 4121 TPLA-TTQRFTYSEKTTLF-----------SKGPEDTSQPSPPS---------------- 4152

Query: 973  ISETSFSTTPTDRTATSLSDGILPPQPTAAHSSATPVPVTHMF----------------- 1015
            + ETS S++     AT+    IL    +  HS ++  PVT +F                 
Sbjct: 4153 VEETSSSSSLVPIHATTSPSNIL--LTSQGHSPSSTPPVTSVFLSETSGLGKTTDMSRIS 4210

Query: 1016 -----SLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVPPLDQT 1070
                 SLP N SS   E   ++  E S   +A   S  + V+N+ +T+   + +P   + 
Sbjct: 4211 LEPGTSLPPNLSSTAGE--ALSTYEASRDTKAIHHSADTAVTNMEATSSEYSPIPGHTKP 4268

Query: 1071 ASTTIVIVPTH--GDLIRTT-----SEATVISV----------RKTSMAVPSLTETPFHS 1113
            +  T  +V +H  GD+  +T     SE T I            R TS    S TET    
Sbjct: 4269 SKATSPLVTSHIMGDITSSTSVFGSSETTEIETVSSVNQGLQERSTSQVASSATETSTVI 4328

Query: 1114 LRLS-----TPVTAKAETTLFSTSVDT-----VTPSTHTLVCSKPPPDNIPPASSTHVIS 1163
              +S     T VT    T    TS+ +      + +T T V + P    I   SS   I+
Sbjct: 4329 THVSSGDATTHVTKTQATFSSGTSISSPHQFITSTNTFTDVSTNPSTSLIMTESSGVTIT 4388

Query: 1164 TTSTP--EATQ-PISQVEETSTYALSFPYTFSGGGVVASLAT----------GTTETSVV 1210
            T + P   ATQ P      T  Y    P   +   + +   T           T+  SV 
Sbjct: 4389 TQTGPTGAATQGPYLLDTSTMPYLTETPLAVTPDFMQSEKTTLISKGPKDVSWTSPPSVA 4448

Query: 1211 DETTPSHISANKLTTSVNSHISSSATYRVHTPVSIQLVTSTSVLSSDKDQMT--ISLGKT 1268
            + + PS ++   L T++    S+       +PVS     +TSVL+S   + T  ++    
Sbjct: 4449 ETSYPSSLTP-FLVTTIPPATSTLQGQHTSSPVS-----ATSVLTSGLVKTTDMLNTSME 4502

Query: 1269 PRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPET-----TKISSHQTHSPSEIPLGTP 1323
            P T     ++   N  ++    T  +E       +      T  S+H  HS     L   
Sbjct: 4503 PVTNSPQNLNNPSNEILATLAATTDIETIHPSINKAVTNMGTASSAHVLHS----TLPVS 4558

Query: 1324 SDGNLASSPTSGSTQITPTLTSSNTVGVHI------PEMSTSLGK---TALPSQALTITT 1374
            S+ + A+SP   ++ +   L S +  G         P  S + G+   + L     T  +
Sbjct: 4559 SEPSTATSPMVPASSMGDALASISIPGSETTDIEGEPTSSLTAGRKENSTLQEMNSTTES 4618

Query: 1375 FLCPEKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSSTRISN--PMDI 1432
             +     S  A+   T    +M V S   T   +  Q T F D  + +S+R+SN  PM I
Sbjct: 4619 NIILSNVSVGAITEAT----KMEVPSFDATFIPTPAQSTKFPDIFSVASSRLSNSPPMTI 4674

Query: 1433 NTTFSHLHSLRTQPEVTSVASFISESTQTFPESLSLSTAGLYNDGFTVLSDRITTAFS-- 1490
            +T     H   TQ   +   S I  +  T     S  T  +  +GF     +ITTA +  
Sbjct: 4675 ST-----HMTTTQTGSSGATSKIPLALDTSTLETSAGTPSVVTEGFA--HSKITTAMNND 4727

Query: 1491 VPNV----PTMLPRESSMATSTPIYQMSSLPVNVTAFTSKKVSDTPPI----VITKSSKT 1542
            V +V    P      SS ++  P+  +++LP +V AFT +  S + P+    V+T S   
Sbjct: 4728 VKDVSQTNPPFQDEASSPSSQAPVL-VTTLPSSV-AFTPQWHSTSSPVSMSSVLTSSLVK 4785

Query: 1543 MHPGCLKSPCTATSGPMS---EMSSIPVNNSAFTPA--------TVSSDTSTRVGLF--- 1588
                   S  T TS P S    +  I V ++A T          TV ++  T    F   
Sbjct: 4786 TAGKVDTSLETVTSSPQSMSNTLDDISVTSAATTDIETTHPSINTVVTNVGTTGSAFESH 4845

Query: 1589 STLLSSVTPR--TTMTMQTSTLDVTPVIYAGATSKNKMVSSAFTTEMIEAPSRITP---T 1643
            ST+ +   P   T+  + TST++ T +      S++   SS  T    E  S +TP    
Sbjct: 4846 STVSAYPEPSKVTSPNVTTSTMEDTTI------SRSIPKSSKTTRTETETTSSLTPKLRE 4899

Query: 1644 TFLSPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSPLSSKSTGAISSI----------PK 1693
            T +S    +     TVP   + G  T    T   S  S+   G   S            +
Sbjct: 4900 TSISQEITSSTETSTVPYKELTGATTEVSRTDVTSSSSTSFPGPDQSTVSLDISTETNTR 4959

Query: 1694 TTFSPFLSATQQSSQADEATTLGILSGIT---NRSLSTVNSGTGVALTDTYSRITVPENM 1750
             + SP ++ + + +   +    G  S  T   + S +T  +G   A+T  +S++ V   M
Sbjct: 4960 LSTSPIMTESAEITITTQTGPHGATSQDTFTMDPSNTTPQAGIHSAMTHGFSQLDVTTLM 5019

Query: 1751 ---------LSPTHADSLHTSFNIQVSPSLT--SFKSASGPTKNVKT-TTNCFSSNTRKM 1798
                      SP   D   +  +   SP++T  S  S++ P   + +  T+  +S   K+
Sbjct: 5020 SRIPQDVSWTSPPSVDKTSSPSSFLSSPAMTTPSLISSTLPEDKLSSPMTSLLTSGLVKI 5079

Query: 1799 TSLLE------KTSLTNYATSLNTPVSYPPWT-------PSSATLPSLTSFVYSPHSTEA 1845
            T +L        +SL N++++ +  ++    +       PS  T  +      S H + +
Sbjct: 5080 TDILRTRLEPVTSSLPNFSSTSDKILATSKDSKDTKEIFPSINTEETNVKANNSGHESHS 5139

Query: 1846 EISTPKTSPPPTSQMVEFPVLGTRMTSSNTQPLLMTSWNIPTAEGSQFPISTTINVPTSN 1905
                   +P  T+QMV    +G    S++      +       E + F         TS 
Sbjct: 5140 PALADSETPKATTQMVITTTVGDPAPSTSMPVHGSSETTNIKREPTYFLTPRLRETSTSQ 5199

Query: 1906 E--METETLHLVPG-PLSTFT-ASQTGLVSKDVMAMSSIPMSGILPNHGLSENPSLSTS- 1960
            E    T+T  L+   P  T T  S TG+ S   ++      S + P+    E P + TS 
Sbjct: 5200 ESSFPTDTSFLLSKVPTGTITEVSSTGVNSSSKISTPDHDKSTVPPDTFTGEIPRVFTSS 5259

Query: 1961 --LRAITSTLADVKHTFEKMTTSVTPGTTLPSILSGATSGSVISKSPI--LTWLLSSLPS 2016
               ++   T+       E  + S  P  T  ++  G T  +V    P   +T L+     
Sbjct: 5260 IKTKSAEMTITTQASPPESASHSTLPLDTSTTLSQGGTHSTVTQGFPYSEVTTLM----- 5314

Query: 2017 GSPPATVSNAPHVMTSSTVEVSKSTFLTSDMISAHPFTNLTTLPSATMSTILTRTIPTPT 2076
            G  P  VS     MT+  VE + S    S ++S+   T+ + + S +  +I +  +P   
Sbjct: 5315 GMGPGNVS----WMTTPPVEETSS---VSSLMSSPAMTSPSPVSSTSPQSIPSSPLPV-- 5365

Query: 2077 LGGITTGFPTSLPMSINVTDDIVYISTHPEASSRTTITANPRTVSHPSSF-----SRKTM 2131
                     T+LP S+ VT   V  +T PE+ + +    +  T   P+++     +   M
Sbjct: 5366 ---------TALPTSVLVTTTDVLGTTSPESVTSSPPNLSSITHERPATYKDTAHTEAAM 5416

Query: 2132 SPSTTDHTLSVG--------------------AMPLPSSTITSSWNRIPTAS---SPSTL 2168
              ST     +VG                    A PL S+T T     + T++   S +  
Sbjct: 5417 HHSTNTAVTNVGTSGSGHKSQSSVLADSETSKATPLMSTTSTLGDTSVSTSTPNISQTNQ 5476

Query: 2169 IIPKPTL-------DSLLNIMTTTSTVPGASFPLISTG-VTYPFTATVSS---PISSFFE 2217
            I  +PT        +S  +  T+++T    +F  + TG +T      +SS    IS    
Sbjct: 5477 IQTEPTASLSPRLRESSTSEKTSSTTETNTAFSYVPTGAITQASRTEISSSRTSISDLDR 5536

Query: 2218 TTWLDSTPSFLSTEASTSPTATKSTVSFYNVEMSFSVFVEEPRIP---ITSVINEFTENS 2274
             T      + + T   TSP  TKS       + +      +  +P    T++    T ++
Sbjct: 5537 PTIAPDISTGMITRLFTSPIMTKSAEMTVTTQTTTPGATSQGILPWDTSTTLFQGGTHST 5596

Query: 2275 LNSIFQNSEFS 2285
            ++  F +SE +
Sbjct: 5597 VSQGFPHSEIT 5607



 Score =  179 bits (453), Expect = 5e-44
 Identities = 465/2248 (20%), Positives = 865/2248 (38%), Gaps = 288/2248 (12%)

Query: 261  QNTAHSSTLLSQSIPIFATDYTTISYSNTTSPPLETMTAQKILKTLVDETATFAVDVLST 320
            +NTA ++   + S+    +  +  S  +  +PP       K+  +++++       ++ST
Sbjct: 6009 ENTAETNMGTTNSMHKLHSSVSIHSQPSGHTPP-------KVTGSMMEDA------IVST 6055

Query: 321  SSAISLPTQSISIDNTTNSMKKTKSPSS-----ESTKTTKMVEAM----ATEIFQPPT-- 369
            S+  S  T+++  D+T+    + K  S+      +T++  +  ++    ATE+ +     
Sbjct: 6056 STPGSPETKNVDRDSTSPLTPELKEDSTALVMNSTTESNTVFSSVSLDAATEVSRAEVTY 6115

Query: 370  --PSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFSTIES-TSMSTTPCLKQKSTNTG 426
              P+   ++++ TK+  +S  ++    ++   T S   TI + T  S    L Q + +T 
Sbjct: 6116 YDPTFMPASAQSTKSPDISPEASSSHSNSPPLTISTHKTIATQTGPSGVTSLGQLTLDTS 6175

Query: 427  ALPISTAG-----QEFIESTAAGTV--PWFTVEKTSPASTHVGTASSFPPEPVLISTA-A 478
             +  S        Q+F++S     +      V KTSP S     + S    P+L++T+ +
Sbjct: 6176 TIATSAGTPSARTQDFVDSETTSVMNNDLNDVLKTSPFSAEEANSLS-SQAPLLVTTSPS 6234

Query: 479  PVDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETTPAPRTAETELTSTNFQDVSLP 538
            PV S    + T+  ++ T +          + T L   T +P+     L +T+       
Sbjct: 6235 PVTSTLQEHSTSSLVSVTSVPTPTLAKITDMDTNLEPVTRSPQNLRNTL-ATSEATTDTH 6293

Query: 539  RVEDAMSTSMSKETSSKTFSFLTSFSFTGTESVQTVIDAEATRTALTPEITLASTVAETM 598
             +  +++T+++   +  T S    F FT        +  ++     T  + + ST  +++
Sbjct: 6294 TMHPSINTAVA---NVGTTSSPNEFYFT--------VSPDSDPYKATSAVVITSTSGDSI 6342

Query: 599  LSSTITGRVYTQNTPTADGHLLTLMSTRSASTSKAPESGPTSTTDEAAHLFSSNETIWTS 658
            +S+++      +   +     L      ++++ K   S  TST  + A   ++ E   T 
Sbjct: 6343 VSTSMPRSSAMKKIESETTFSLIFRLRETSTSQKIGSSSDTSTVFDKAFTAATTEVSRTE 6402

Query: 659  RPDQALLASMNTTTILTFVPNENFTSAFHENT----TYTEYLSATTNITPLKASPEG--- 711
                +   S+  T   T  P+ +  S    +T    T +E  +  T   P +A+ +G   
Sbjct: 6403 LTSSS-RTSIQGTEKPTMSPDTSTRSVTMLSTFAGLTKSEERTIATQTGPHRATSQGTLT 6461

Query: 712  ---KGTTANDATTARYTTAVSKL---------------TSPWFANFSIVSGTTSITNMPE 753
                 TT+   T +  T   S+L               TSP   +    S ++S+ ++P 
Sbjct: 6462 WDTSITTSQAGTHSAMTHGFSQLDLSTLTSRVPEYISGTSP--PSVEKTSSSSSLLSLPA 6519

Query: 754  FKLTTLLLKTIPMSTKPANELPLT--PRETVVPSVDIISTLACIQPNFSTEESASETTQT 811
                + +  T+P S +P++ + LT  P   +V + D+++++A + PN  +      TT  
Sbjct: 6520 ITSPSPVPTTLPES-RPSSPVHLTSLPTSGLVKTTDMLASVASLPPNLGSTSHKIPTTSE 6578

Query: 812  EINGA-IVFGGTTTPVPKSATTQRLNATVTRKEATSHYLMRKSTIAAVAEVSPFSTMLEV 870
            +I     ++  T   V    TT     + +   A S     K T   V   +   T++  
Sbjct: 6579 DIKDTEKMYPSTNIAVTNVGTTTSEKESYSSVPAYSE--PPKVTSPMVTSFNIRDTIVST 6636

Query: 871  TDESAQRVTASVTVSSFPDIEKLSTPLDNKTATTEVRESWLLTKLVKTTPRSSYNEMTEM 930
            +   +  +T     S+F     L     ++       +S +L KL      +S  E+   
Sbjct: 6637 SMPGSSEITRIEMESTFSLAHGLKGTSTSQDPIVSTEKSAVLHKLTTGATETSRTEVAS- 6695

Query: 931  FNFNHTYVAHWTSETSEGISAGSPTSGSTHIFGEPLGASTTRISETSFSTTPTDRTATSL 990
                    +  TS      S  SP   +  I   P+    T  S  +  T       ++ 
Sbjct: 6696 --------SRRTSIPGPDHSTESPDISTEVIPSLPISLGITESSNMTIITRTGPPLGSTS 6747

Query: 991  SDGILPPQPTAAHSSATPVPVTHMFSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSD 1050
                    PT +  + T    T  F          +E T V   +P  L+     S+  +
Sbjct: 6748 QGTFTLDTPTTSSRAGTHSMATQEFP--------HSEMTTVMNKDPEILSWTIPPSI--E 6797

Query: 1051 VSNLSSTTMTTALV--PPLDQTASTTIVIVPTHGDLIRT-----TSEATVISVRKTSMAV 1103
             ++ SS+ M +  +  PP+  T   TI   P+    + T     T++    S   T+ + 
Sbjct: 6798 KTSFSSSLMPSPAMTSPPVSSTLPKTIHTTPSPMTSLLTPSLVMTTDTLGTSPEPTTSSP 6857

Query: 1104 PSLTETPFHSLRLSTPVTA----KAETTLFSTSVDTVTP---STHTLVCSKPPPDNIPPA 1156
            P+L+ T    L      TA       T+  +T+V+T +    S  +++          P 
Sbjct: 6858 PNLSSTSHEILTTDEDTTAIEAMHPSTSTAATNVETTSSGHGSQSSVLADSEKTKATAPM 6917

Query: 1157 SSTHVISTT---STPEATQPISQVEETSTYALSFPYTFSGGGVVASLATGTT-ETSVVDE 1212
             +T  +  T   ++   +   ++++  STY+L+     +     AS +T T+   S V  
Sbjct: 6918 DTTSTMGHTTVSTSMSVSSETTKIKRESTYSLTPGLRETSISQNASFSTDTSIVLSEVPT 6977

Query: 1213 TTPSHISANKLTTSVNSHISSSATYRVHTPVSIQLVTS--TSVLSSDKDQMTISL----- 1265
             T + +S  ++T+S  + I   +   V   +S + +T    S   ++  +MTI       
Sbjct: 6978 GTTAEVSRTEVTSSGRTSIPGPSQSTVLPEISTRTMTRLFASPTMTESAEMTIPTQTGPS 7037

Query: 1266 GKTPRTMEVTEMSPSKNSFISYSRGT---PSLEMT---DTGFPETTKISSHQTHSPSEIP 1319
            G T +     + S +K+   ++S  T   P  EMT     G  + +  SS    +PS +P
Sbjct: 7038 GSTSQDTLTLDTSTTKSQAKTHSTLTQRFPHSEMTTLMSRGPGDMSWQSSPSLENPSSLP 7097

Query: 1320 ---------LGTPSDGNLASSPTSGSTQITPTLTSSNTVGVHIPEMSTSLGKTALPSQAL 1370
                        P    L  + +S    +T  LTSS      +   S  L  ++ P  + 
Sbjct: 7098 SLLSLPATTSPPPISSTLPVTISSSPLPVTSLLTSSPVTTTDMLHTSPELVTSSPPKLSH 7157

Query: 1371 TITTFLCPEKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSSTR----I 1426
            T    L   K++T+   A  P T     ++  +  S      ++  D+ TS +T      
Sbjct: 7158 TSDERLTTGKDTTNT-EAVHPST-NTAASNVEIPSSGHESPSSALADSETSKATSPMFIT 7215

Query: 1427 SNPMDINTTFSHLHSLRT----QPEVTSVASFISESTQTFPESLSLSTAGLYND------ 1476
            S   D     S  H L T    +  ++S++  + E+  +   S ++ T+ + ++      
Sbjct: 7216 STQEDTTVAISTPHFLETSRIQKESISSLSPKLRETGSSVETSSAIETSAVLSEVSIGAT 7275

Query: 1477 ---GFTVLSDRITTAFSVPNVPTMLPRESS------MATSTPIYQMSSLPVNV------- 1520
                 T ++    T+ S     TMLP  S+        TS  + + S + +         
Sbjct: 7276 TEISRTEVTSSSRTSISGSAESTMLPEISTTRKIIKFPTSPILAESSEMTIKTQTSPPGS 7335

Query: 1521 ---TAFTSKKVSDTPPIVITKSSKT--MHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPA 1575
               + FT    S TP +VIT S+ T  +    + +  +  +G +   SS+PV  +    +
Sbjct: 7336 TSESTFT-LDTSTTPSLVITHSTMTQRLPHSEITTLVSRGAGDVPRPSSLPVEET----S 7390

Query: 1576 TVSSDTSTRVGLFSTLLSSVTPRTTMTMQTSTLDVTPVIYAGATSKNKMVSSAFTTEMIE 1635
              SS  S    +  + +SS  P ++    +S+  VT ++  G            TTE+++
Sbjct: 7391 PPSSQLSLSAMISPSPVSSTLPASS---HSSSASVTSLLTPGQVK---------TTEVLD 7438

Query: 1636 APSRITPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSPLSSKSTGAISSIPKTT 1695
            A +    ++  S +  ++  + T   T     + PF   TA + + + S+G  S      
Sbjct: 7439 ASAEPETSSPPSLSSTSVEILATSEVTTDTEKIHPF-SNTAVTKVGTSSSGHESP----- 7492

Query: 1696 FSPFLSATQQSSQADEATTLGILSGITNRSLSTVNSGTGVALTDTYSRITVPENMLSPTH 1755
             S  L  ++ +       T+ I+   +  +L+   S T    ++  S +T      S + 
Sbjct: 7493 -SSVLPDSETTKATSAMGTISIMGDTSVSTLTPALSNTRKIQSEPASSLTTRLRETSTSE 7551

Query: 1756 ADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLLEKTSLTNYATSLN 1815
              SL T  N  +S      K ++G T  V + T   S +   M+   + T   + +    
Sbjct: 7552 ETSLATEANTVLS------KVSTGATTEV-SRTEAISFSRTSMSGPEQSTMSQDISIGTI 7604

Query: 1816 TPVSYPPWTPSSATLPSLTSFVYSPHSTEAEISTPKTSPPPTSQMVEFPVLG---TRMTS 1872
              +S       SA +   T    S  + E+ ++    + P   +     + G     MT+
Sbjct: 7605 PRISASSVLTESAKMTITTQTGPSESTLESTLNLNTATTPSWVETHSIVIQGFPHPEMTT 7664

Query: 1873 SNTQPLLMTSWNIPTAEGSQFPISTTINVP--TSNEMETETL--HLVPGPLSTFTASQTG 1928
            S  +     SW  P       P S+ +++P  TS    + T   H+ P PL   +   +G
Sbjct: 7665 SMGRGPGGVSWPSPPFVKETSPPSSPLSLPAVTSPHPVSTTFLAHIPPSPLPVTSLLTSG 7724

Query: 1929 -LVSKDVMAMSSIPMSGILPNHGLSENPSLSTSLRAITSTLADVKHTFEKMTTSVTPGTT 1987
               + D++  S+ P        G S + SLST+     +T  D  HT     ++ T GT 
Sbjct: 7725 PATTTDILGTSTEP--------GTSSSSSLSTTSHERLTTYKDTAHTEAVHPSTNTGGTN 7776

Query: 1988 LPSILSGATSGSVISKSPILTWLLSSLPSGSPPATVSNAPHVMTSSTVEVSKSTFLTSDM 2047
            + +  SG  S S            S L   SP  T S     M  ++V  S   FL +  
Sbjct: 7777 VATTSSGYKSQS------------SVLADSSPMCTTS----TMGDTSVLTSTPAFLETRR 7820

Query: 2048 ISAHPFTNLT-----------TLPSATMSTILTRTIPTPTLGGITTGFPTSLP------M 2090
            I     ++LT           T     MST+L++ +PT     I+    TS+P      +
Sbjct: 7821 IQTELASSLTPGLRESSGSEGTSSGTKMSTVLSK-VPTGATTEISKEDVTSIPGPAQSTI 7879

Query: 2091 SINV-TDDIVYISTHPEASSRTTITANPRTVSHPSSFSRKTMSPSTTDHTLSVGAMPLPS 2149
            S ++ T  + + ST P  +    IT N    +H S     T   ST D T S  ++ +  
Sbjct: 7880 SPDISTRTVSWFSTSPVMTESAEITMN----THTSPLGATTQGTSTLD-TSSTTSLTMTH 7934

Query: 2150 STITSSWNRIPTASSPSTLIIPKPTLDSLLNIMTTTSTVPGASFPLISTGVTYPFTATVS 2209
            STI+  ++     S  STL+   P   S ++      T P  SF L+S+  T    + VS
Sbjct: 7935 STISQGFSH----SQMSTLMRRGPEDVSWMSPPLLEKTRP--SFSLMSSPAT-TSPSPVS 7987

Query: 2210 SPISSFFETTWLDSTPSFLSTEASTSPTATKSTVSFYNVEMSFSVFVEEPRIPITSVINE 2269
            S +     ++ L  T    S  A T+    KS+    N   + S    E  I  TS +  
Sbjct: 7988 STLPESISSSPLPVTSLLTSGLAKTTDMLHKSSEPVTNSPANLSSTSVE--ILATSEVTT 8045

Query: 2270 FTE-------------NSLNSIFQNSEFSLATLETQIKSRDISEEEMVMDRAILEQREG- 2315
             TE              + +S  +++ F LA  +T   +  +     + D ++     G 
Sbjct: 8046 DTEKTHPSSNRTVTDVGTSSSGHESTSFVLADSQTSKVTSPMVITSTMEDTSVSTSTPGF 8105

Query: 2316 QEMATISYVPYSCVCQVIIKASSSLASS 2343
             E + I   P S +   + K SSS  +S
Sbjct: 8106 FETSRIQTEPTSSLTLGLRKTSSSEGTS 8133



 Score =  178 bits (451), Expect = 8e-44
 Identities = 467/2162 (21%), Positives = 838/2162 (38%), Gaps = 290/2162 (13%)

Query: 266  SSTLLSQSIPIFATDYTTISYSNTTSPPLETMTAQKILKTLVDETATFAVDVLSTSSAIS 325
            SS L S  +     +   +S S TT P  E+  A+    + +          + TSS   
Sbjct: 3974 SSKLTSPVVTTSTREQAIVSMSTTTWP--ESTRARTEPNSFLTIELRDVSPYMDTSS--- 4028

Query: 326  LPTQSISIDNTTNSMKKTKSPSSESTKTTKMVEA-MATEIFQPPTPS-------NFLSTS 377
              T   SI ++  S   TK P +E T + ++  + +A  +    +PS       NF + +
Sbjct: 4029 --TTQTSIISSPGSTAITKGPRTEITSSKRISSSFLAQSMRSSDSPSEAITRLSNFPAMT 4086

Query: 378  RFTKNSVVSTTS--AIKSQSAVTKTTSLFSTIESTSMSTTPCLKQKSTNTGALPISTAGQ 435
                  +   TS     S SA T  TS  ++   T ++TT    Q+ T +    + + G 
Sbjct: 4087 ESGGMILAMQTSPPGATSLSAPTLDTSATASWTGTPLATT----QRFTYSEKTTLFSKGP 4142

Query: 436  EFIESTAAGTVPWFTVEKTSPASTHVGTASSFPPEPVLI-------STAAPVDSVFPRNQ 488
            E    T+  + P  +VE+TS +S+ V   ++  P  +L+       S+  PV SVF  ++
Sbjct: 4143 E---DTSQPSPP--SVEETSSSSSLVPIHATTSPSNILLTSQGHSPSSTPPVTSVF-LSE 4196

Query: 489  TAFPLATTDMKIAFTVHSLTLPTRL-------IETTPAPR----------TAETELTSTN 531
            T+    TTDM         +LP  L       + T  A R          TA T + +T+
Sbjct: 4197 TSGLGKTTDMSRISLEPGTSLPPNLSSTAGEALSTYEASRDTKAIHHSADTAVTNMEATS 4256

Query: 532  FQDVSLP---RVEDAMSTSMSKETSSKTFSFLTSFSFTGTESVQTVIDA-EATRTALTPE 587
             +   +P   +   A S  ++        S  + F  + T  ++TV    +  +   T +
Sbjct: 4257 SEYSPIPGHTKPSKATSPLVTSHIMGDITSSTSVFGSSETTEIETVSSVNQGLQERSTSQ 4316

Query: 588  ITLASTVAETMLSSTITGRVYTQNTPT--------------------------ADGHLLT 621
            +  ++T   T+++   +G   T  T T                          +     +
Sbjct: 4317 VASSATETSTVITHVSSGDATTHVTKTQATFSSGTSISSPHQFITSTNTFTDVSTNPSTS 4376

Query: 622  LMSTRSASTSKAPESGPTSTTDEAAHLFSSN------ETIWTSRPDQALLASMNTTTILT 675
            L+ T S+  +   ++GPT    +  +L  ++      ET     PD   + S  TT I  
Sbjct: 4377 LIMTESSGVTITTQTGPTGAATQGPYLLDTSTMPYLTETPLAVTPD--FMQSEKTTLISK 4434

Query: 676  FVPNENFTSAFH-ENTTYTEYLSA--TTNITPLKASPEGKGTTANDATTARYTTAVSKLT 732
               + ++TS      T+Y   L+    T I P  ++ +G+ T++  + T+  T+ + K T
Sbjct: 4435 GPKDVSWTSPPSVAETSYPSSLTPFLVTTIPPATSTLQGQHTSSPVSATSVLTSGLVKTT 4494

Query: 733  SPWFANFSIVSGTTSITNMPEFKLTTLLLKTIPMST-KPANELPLTPRETVVPSVDIIST 791
                 +   V+ +    N P  ++   L  T  + T  P+    +T   T   +  + ST
Sbjct: 4495 DMLNTSMEPVTNSPQNLNNPSNEILATLAATTDIETIHPSINKAVTNMGTASSAHVLHST 4554

Query: 792  L-ACIQPNFSTEESASETTQTEINGAIVFGGTTT------PVPKSATTQRLNATVTRKEA 844
            L    +P+ +T      ++  +   +I   G+ T      P       ++ N+T+    +
Sbjct: 4555 LPVSSEPSTATSPMVPASSMGDALASISIPGSETTDIEGEPTSSLTAGRKENSTLQEMNS 4614

Query: 845  T--SHYLMRKSTIAAVAEVSPFSTMLEVTDESAQRVTASVTVSSFPDIEKL-STPLDNKT 901
            T  S+ ++   ++ A+ E    +T +EV    A  +      + FPDI  + S+ L N  
Sbjct: 4615 TTESNIILSNVSVGAITE----ATKMEVPSFDATFIPTPAQSTKFPDIFSVASSRLSNSP 4670

Query: 902  ATTEVRESWLLTKLVKTTPRSSYNEMTEMFNFNHTYVAHWTSETSEGISAGSPTSGSTHI 961
              T       ++  + TT   S    +++     T     T ETS G +    T G  H 
Sbjct: 4671 PMT-------ISTHMTTTQTGSSGATSKIPLALDTS----TLETSAG-TPSVVTEGFAH- 4717

Query: 962  FGEPLGASTTRISETSFSTTPTDRTATSLSDGILPPQPTAAHSSATPVPVTHMFSLPVNG 1021
              +   A    + + S +  P    A+S S    P   T   SS    P  H  S PV+ 
Sbjct: 4718 -SKITTAMNNDVKDVSQTNPPFQDEASSPSSQA-PVLVTTLPSSVAFTPQWHSTSSPVSM 4775

Query: 1022 SSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVPPLDQTASTTIVIVPTH 1081
            SSV+      T  +  T     ++S  S  + L   ++T+A    ++ T  +   +V   
Sbjct: 4776 SSVLTSSLVKTAGKVDTSLETVTSSPQSMSNTLDDISVTSAATTDIETTHPSINTVVTNV 4835

Query: 1082 GDLIRTTSEATVISVRKTSMAVPSLTETPFHSLRLSTPVTAKAETTLFSTSVDTVTPSTH 1141
            G    TT  A       ++   PS   +P          T+  E T  S S+   + +T 
Sbjct: 4836 G----TTGSAFESHSTVSAYPEPSKVTSP-------NVTTSTMEDTTISRSIPKSSKTTR 4884

Query: 1142 TLVCSKPPPDNIPPASSTHVISTTSTPEATQPISQVEETSTYALSFPYTFSGGGVVASLA 1201
            T                T   S+ +       ISQ   +ST   + PY          L 
Sbjct: 4885 T---------------ETETTSSLTPKLRETSISQEITSSTETSTVPYK--------ELT 4921

Query: 1202 TGTTETSVVDETTPSHISANKLTTSVNSHISSSATYRVHTPVSIQLVTSTSVLSSDKDQM 1261
              TTE S  D T+ S       +TS      S+ +  + T  + +L  STS + ++  ++
Sbjct: 4922 GATTEVSRTDVTSSS-------STSFPGPDQSTVSLDISTETNTRL--STSPIMTESAEI 4972

Query: 1262 TISLGKTPR--------TMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTH 1313
            TI+    P         TM+ +  +P      + + G   L++T              + 
Sbjct: 4973 TITTQTGPHGATSQDTFTMDPSNTTPQAGIHSAMTHGFSQLDVTTL-----------MSR 5021

Query: 1314 SPSEIPLGTPSDGNLASSPTSGSTQITPTLTSSNTVGVHIPEMSTSLGKTALPSQALT-I 1372
             P ++   +P   +  SSP+S  +  +P +T+ + +   +PE   S   T+L +  L  I
Sbjct: 5022 IPQDVSWTSPPSVDKTSSPSSFLS--SPAMTTPSLISSTLPEDKLSSPMTSLLTSGLVKI 5079

Query: 1373 TTFLCPEKES-TSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSSTRISNPMD 1431
            T  L    E  TS+LP ++  + +++  S          +DT   +   S +T  +N + 
Sbjct: 5080 TDILRTRLEPVTSSLPNFSSTSDKILATS-------KDSKDTK--EIFPSINTEETN-VK 5129

Query: 1432 INTTFSHLHSLRTQPEVTSVASFISESTQTFPESLSLSTAGLYNDGFTVLSDRITTAFSV 1491
             N +    HS       T  A+     T T  +    ++  ++    T    R  T F  
Sbjct: 5130 ANNSGHESHSPALADSETPKATTQMVITTTVGDPAPSTSMPVHGSSETTNIKREPTYFLT 5189

Query: 1492 PNV-PTMLPRESSMATSTPIYQMSSLPVN-VTAFTSKKVSDTPPIVITKSSKTMHPGCL- 1548
            P +  T   +ESS  T T  + +S +P   +T  +S  V+ +  I      K+  P    
Sbjct: 5190 PRLRETSTSQESSFPTDTS-FLLSKVPTGTITEVSSTGVNSSSKISTPDHDKSTVPPDTF 5248

Query: 1549 --KSPCTATSGPMSEMSSIPVNNSAFTP-----ATVSSDTSTRVGLFSTLLSSVTPRTTM 1601
              + P   TS   ++ + + +   A  P     +T+  DTST +    T  S+VT     
Sbjct: 5249 TGEIPRVFTSSIKTKSAEMTITTQASPPESASHSTLPLDTSTTLSQGGTH-STVTQGFPY 5307

Query: 1602 TMQTSTLDVTPVIYAGATS----KNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTLPFVK 1657
            +  T+ + + P   +  T+    +   VSS  ++  + +PS ++ T+  S     LP V 
Sbjct: 5308 SEVTTLMGMGPGNVSWMTTPPVEETSSVSSLMSSPAMTSPSPVSSTSPQSIPSSPLP-VT 5366

Query: 1658 TVPTTIMAGIVTPFVGTTAFSPLSSKSTGAISSIPKTTFSPFLSATQQSSQADEATTLGI 1717
             +PT+++    T  +GTT+   ++S S   +SSI     + +       +    +T   +
Sbjct: 5367 ALPTSVLV-TTTDVLGTTSPESVTS-SPPNLSSITHERPATYKDTAHTEAAMHHSTNTAV 5424

Query: 1718 L----SGITNRSLSTV--NSGTGVAL-----TDTYSRITVPENMLSPTHADSLHTSFNIQ 1766
                 SG  ++S S+V  +S T  A      T T    +V  +  + +  + + T     
Sbjct: 5425 TNVGTSGSGHKSQSSVLADSETSKATPLMSTTSTLGDTSVSTSTPNISQTNQIQTEPTAS 5484

Query: 1767 VSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLLEKTSLTNYATSLNTPVSYPPWTPS 1826
            +SP L    S S  T +   T   FS       +   +T +++  TS++  +  P   P 
Sbjct: 5485 LSPRLRE-SSTSEKTSSTTETNTAFSYVPTGAITQASRTEISSSRTSISD-LDRPTIAPD 5542

Query: 1827 SATLPSLTSFVYSP---HSTEAEISTPKTSPPPTSQMVEFPVLGTRMTSSNTQPLLMTSW 1883
             +T   +T    SP    S E  ++T  T+P  TSQ +        +    +  L     
Sbjct: 5543 IST-GMITRLFTSPIMTKSAEMTVTTQTTTPGATSQGI--------LPWDTSTTLFQGGT 5593

Query: 1884 NIPTAEGSQFPISTTINVPTSNEMETETLHLVPGPLSTFTASQTGLVSKDVMAMSSIPMS 1943
            +   ++G      TT+   T  ++   T   V    S F+     + S   ++ +S P S
Sbjct: 5594 HSTVSQGFPHSEITTLRSRTPGDVSWMTTPPVEETSSGFSLMSPSMTSPSPVSSTS-PES 5652

Query: 1944 GILPNHGLSENPSLSTSLRAITSTLADVKHTFEKMTTSVTPGTTLPSILSGATSGSVIS- 2002
              +P+  L     L++ L   T+ L          TTS  P T+ P  LS  T   + + 
Sbjct: 5653 --IPSSPLPVTALLTSVLVTTTNVLG---------TTSPEPVTSSPPNLSSPTQERLTTY 5701

Query: 2003 KSPILTWLL-SSLPSGSPPATV--SNAPHVMTSSTVEVSKSTFLTSDMISAHPFTNLTTL 2059
            K    T  + +S+ + +  A V  S + H   SS    S ++  TS M       + T++
Sbjct: 5702 KDTAHTEAMHASMHTNTAVANVGTSISGHESQSSVPADSHTSKATSPMGITFAMGD-TSV 5760

Query: 2060 PSATMSTILTRTIPTPTLGGITTGF-PTSLPMSIN-VTDDIVYISTHP-----EASSRTT 2112
             ++T +   TR I T +   +  G   T     IN VT+    +S  P     E S    
Sbjct: 5761 STSTPAFFETR-IQTESTSSLIPGLRDTRTSEEINTVTETSTVLSEVPTTTTTEVSRTEV 5819

Query: 2113 ITANPRTVSHPSSFSRKTMSPSTTDHTLS-VGAMPLPSST----ITSSWNRIPTASSPST 2167
            IT++  T+S P       MSP  +  T++ +   P  + +    IT+    I T S  + 
Sbjct: 5820 ITSSRTTISGPD---HSKMSPYISTETITRLSTFPFVTGSTEMAITNQTGPIGTISQATL 5876

Query: 2168 LIIPKPTLDSLLNIMTTTSTVPGASFPLISTGVTYPFTATVSSPISSFFETTWLDSTPSF 2227
                  TLD+     ++T++  G   P+      +P +   ++   S    +W  S PS 
Sbjct: 5877 ------TLDT-----SSTASWEGTHSPVTQR---FPHSEETTTMSRSTKGVSW-QSPPSV 5921

Query: 2228 LSTEASTSPTATKSTVSFYNVEMSFSVFVEEPRIPITSVINEFTENSLNSIFQNSEFSLA 2287
              T + +SP    +  S  ++  + S       +P+TS++      +++ +  +SE   +
Sbjct: 5922 EETSSPSSPVPLPAITSHSSLYSAVSGSSPTSALPVTSLLTSGRRKTIDMLDTHSELVTS 5981

Query: 2288 TL 2289
            +L
Sbjct: 5982 SL 5983



 Score =  174 bits (442), Expect = 9e-43
 Identities = 476/2213 (21%), Positives = 821/2213 (37%), Gaps = 266/2213 (12%)

Query: 259  KPQNTAHSSTLLSQSIPIFATDYTTISYSNTTSPPLETMTAQKILKTLVDETATFAVDVL 318
            K  +   S++L S+   +F+T     S S+++   L T      L      +   ++  L
Sbjct: 2999 KASSAMTSTSLASKLTTLFSTGQAARSGSSSSPISLSTEKETSFLSPTASTSRKTSL-FL 3057

Query: 319  STSSA------ISLPTQSISIDNT-TNSMKKTKSPSSESTKTTKMVEAMATEI----FQP 367
              S A      + L T ++++  T T +M + + P   S++T    E    E     F P
Sbjct: 3058 GPSMARQPNILVHLQTSALTLSPTSTLNMSQEEPPELTSSQTIAEEEGTTAETQTLTFTP 3117

Query: 368  P-TPSNFLSTSRFTKNSV--VSTTSAIKSQSAVTKTTSLFSTIESTSMSTTPCLKQKSTN 424
              TP++ L  S  T+ +    S+     S  +V   TSL  T + T ++T     Q +  
Sbjct: 3118 SETPTSLLPVSSPTEPTARRKSSPETWASSISVPAKTSLVETTDGTLVTTIKMSSQAAQG 3177

Query: 425  TGALPISTAGQEFIESTAAGTVPWFTVEKTSPASTHVGTASSFPPE--PVLISTAAPVDS 482
                P   A  E   S+ AGT P      +   ST +   SS  P   P + ST    +S
Sbjct: 3178 NSTWP---APAEETGSSPAGTSPG-----SPEMSTTLKIMSSKEPSISPEIRSTVR--NS 3227

Query: 483  VFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETTPAPRTAETELTSTNF---QDVSLPR 539
             +   +T  P+ TT   +     +L   +  I   P   T+ T+  + N    + VSL  
Sbjct: 3228 PWKTPETTVPMETTVEPVTLQSTALGSGSTSISHLPTGTTSPTKSPTENMLATERVSLSP 3287

Query: 540  VEDAMSTSMSKETSSKTFSFLTSFSFTGTESVQTVIDAEATRTALTPEITLASTVAETML 599
                  T++   T   T   L + S    ES  T      T    +PE+   +T  E  +
Sbjct: 3288 SPPEAWTNLYSGTPGGTRQSLATMSSVSLES-PTARSITGTGQQSSPELVSKTTGMEFSM 3346

Query: 600  SSTITGRVYTQNTPTADGHLLTLMSTRSASTSKAPESGPTSTTDEAAHLFSSNETIWTSR 659
                TG        T D H+    S+          +  +S TD++ H     ET W S 
Sbjct: 3347 WHGSTGGT------TGDTHVSLSTSSNILEDPVTSPNSVSSLTDKSKH---KTET-WVST 3396

Query: 660  PDQALLASMNTTTILTFVPNENFTSAFHENTTYTEYLSATTNITPLKASPEGKGT---TA 716
                     N         + +   A+   +++++  S + +IT L ASP+   T   T+
Sbjct: 3397 TAIPSTVLNNKIMAAEQQTSRSVDEAYSSTSSWSDQTSGS-DIT-LGASPDVTNTLYITS 3454

Query: 717  NDATTARYTT-----AVSKLTSPWFANFSIVSGTTSITNMPEFKLTTLLLKTIPMSTKPA 771
               TT+  +       ++ LT+P     S  S  TS    P   L TL      + +  A
Sbjct: 3455 TAQTTSLVSLPSGDQGITSLTNPSGGKTSSASSVTS----PSIGLETLRANVSAVKSDIA 3510

Query: 772  NELPLTPRETVVPSVDIISTLACIQPNFSTEESASETTQTEINGAIVFGGTTTPVPK--S 829
                   + +    V I+       P  ST  +   T             TTTP P+   
Sbjct: 3511 PTAGHLSQTSSPAEVSILDVTTAPTPGISTTITTMGTNSIS---------TTTPNPEVGM 3561

Query: 830  ATTQRLNATVTRKEATSHYLMRKSTIAAVA-EVSPFSTMLEVTDESAQRVTASVT--VSS 886
            +T     AT  R  +T H     ST A+ +  V+  ++ L+V        T   T  ++S
Sbjct: 3562 STMDSTPATERRTTSTEHPSTWSSTAASDSWTVTDMTSNLKVARSPGTISTMHTTSFLAS 3621

Query: 887  FPDIEKLSTPLDN------------------KTATTEVRESWLLTKLVKTTPRSSYNEMT 928
              +++ +STP                     KT T+    +   +    +TP S+++ + 
Sbjct: 3622 STELDSMSTPHGRITVIGTSLVTPSSDASAVKTETSTSERTLSPSDTTASTPISTFSRVQ 3681

Query: 929  EM-FNFNHTYVAHWTSETSEGIS----------AGSPTSGSTHIFGEPLGASTTRISETS 977
             M  +        WT  ++E             A + T  +T +      + +T   +T 
Sbjct: 3682 RMSISVPDILSTSWTPSSTEAEDVPVSMVSTDHASTKTDPNTPLSTFLFDSLSTLDWDTG 3741

Query: 978  FSTTPTDRTATSLSDGILPPQPTAAHSSATPVPVTHMFSLPVNGSSVVAEETEVTMSEPS 1037
             S +    T TS   G   PQ     +  +P        LP +   + +  T   M+  S
Sbjct: 3742 RSLSSATAT-TSAPQGATTPQELTLETMISPATS----QLPFSIGHITSAVTPAAMARSS 3796

Query: 1038 --TLARAFSTSVLSDVSNLSSTTMTTALVPPLDQTASTTIVIVPTHGDLIRTTSEATVIS 1095
              T +R   TS  ++ ++    T T+A    + ++A+TT+ ++P        T +AT   
Sbjct: 3797 GVTFSRPDPTSKKAEQTSTQLPTTTSAHPGQVPRSAATTLDVIPHTAK----TPDATFQR 3852

Query: 1096 VRKTSMAVPS-LTETPFHSLRLSTPVTAKAETTLFSTSVDT---VTPSTHTL-------- 1143
              +T++   +  T   ++    STP        + S S DT   VT S+  L        
Sbjct: 3853 QGQTALTTEARATSDSWNEKEKSTPSAPWITEMMNSVSEDTIKEVTSSSSVLRTLNTLDI 3912

Query: 1144 -----VCSKP-----PPDNIPPASSTH----VISTTSTPEATQPISQVEETSTYALSFPY 1189
                   S P     P + I P+ ST     +  +T+T E T  ++  E  S   +   +
Sbjct: 3913 NLESGTTSSPSWKSSPYERIAPSESTTDKEAIHPSTNTVETTGWVTSSEHASHSTIP-AH 3971

Query: 1190 TFSGGGVVASLATGTTETSVVDETTPSHISANKLTTSVNSHISSSATYRVHTPVSIQLVT 1249
            + S       + T T E ++V  +T +   + +  T  NS ++      V   +     T
Sbjct: 3972 SASSKLTSPVVTTSTREQAIVSMSTTTWPESTRARTEPNSFLTIELR-DVSPYMDTSSTT 4030

Query: 1250 STSVLSSDKDQMTISLGKTPRTMEVTEMSPSKNSFISYSR---GTPSLEMTD-TGFPETT 1305
             TS++SS     + ++ K PRT E+T      +SF++ S     +PS  +T  + FP  T
Sbjct: 4031 QTSIISSPG---STAITKGPRT-EITSSKRISSSFLAQSMRSSDSPSEAITRLSNFPAMT 4086

Query: 1306 K----ISSHQTHSPSEIPLGTPSDGNLASSPTSGSTQITPTLTSSNTVGVHIPEMSTSLG 1361
            +    I + QT  P    L  P+   L +S T+  T      T   T        S    
Sbjct: 4087 ESGGMILAMQTSPPGATSLSAPT---LDTSATASWTGTPLATTQRFTYSEKTTLFSKGPE 4143

Query: 1362 KTALPSQALTITTFLCPEKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTS 1421
             T+ PS          P  E TS+  +  P       ++  +T   S G   S     TS
Sbjct: 4144 DTSQPSP---------PSVEETSSSSSLVPIHATTSPSNILLT---SQGHSPSSTPPVTS 4191

Query: 1422 SSTRISNPMDINTTFSHLHSLRTQPEVTSVASFISESTQTFPESLSLSTAGLYNDGFTVL 1481
                 ++ +   T  S +          +++S   E+  T+    S  T  +++   T +
Sbjct: 4192 VFLSETSGLGKTTDMSRISLEPGTSLPPNLSSTAGEALSTY--EASRDTKAIHHSADTAV 4249

Query: 1482 SDRITTAFSVPNVPTMLPRESSMATSTPIYQMSSLPVNVTAFTSKKVSDTPPIV-ITKSS 1540
            ++   T+     +P       + +     + M  +  + + F S + ++   +  + +  
Sbjct: 4250 TNMEATSSEYSPIPGHTKPSKATSPLVTSHIMGDITSSTSVFGSSETTEIETVSSVNQGL 4309

Query: 1541 KTMHPGCLKSPCTATSGPMSEMSSIPVNNSAF-TPATVSSDTS--------TRVGLFSTL 1591
            +      + S  T TS  ++ +SS         T AT SS TS        T    F+ +
Sbjct: 4310 QERSTSQVASSATETSTVITHVSSGDATTHVTKTQATFSSGTSISSPHQFITSTNTFTDV 4369

Query: 1592 LSSVTPRTTMTMQTSTLDVTPVIYAG----ATSKNKMVSSAFTTEMIEAPSRITP----- 1642
              S  P T++ M T +  VT     G    AT    ++ ++    + E P  +TP     
Sbjct: 4370 --STNPSTSLIM-TESSGVTITTQTGPTGAATQGPYLLDTSTMPYLTETPLAVTPDFMQS 4426

Query: 1643 --TTFLS--PTEPTLPFVKTVPTTIMAGIVTPFVGTT---AFSPLSSKSTGAISSIPKTT 1695
              TT +S  P + +     +V  T     +TPF+ TT   A S L  + T +  S     
Sbjct: 4427 EKTTLISKGPKDVSWTSPPSVAETSYPSSLTPFLVTTIPPATSTLQGQHTSSPVSATSVL 4486

Query: 1696 FSPFLSATQQSSQADEATTLGI--LSGITNRSLSTVNSGTGVALTDTYSRITVPENMLSP 1753
             S  +  T   + + E  T     L+  +N  L+T+ + T +          V  NM + 
Sbjct: 4487 TSGLVKTTDMLNTSMEPVTNSPQNLNNPSNEILATLAATTDIETIHPSINKAVT-NMGTA 4545

Query: 1754 THADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLL-EKTSLTNYAT 1812
            + A  LH++  +   PS  +  S   P  ++       S    + T +  E TS      
Sbjct: 4546 SSAHVLHSTLPVSSEPSTAT--SPMVPASSMGDALASISIPGSETTDIEGEPTSSLTAGR 4603

Query: 1813 SLNTPVSYPPWTPSSATLPSLTSFVYSPHSTEAEI-STPKTSPPPTSQMVEFPVLGTRMT 1871
              N+ +     T  S  + S  S      +T+ E+ S   T  P  +Q  +FP + +  +
Sbjct: 4604 KENSTLQEMNSTTESNIILSNVSVGAITEATKMEVPSFDATFIPTPAQSTKFPDIFSVAS 4663

Query: 1872 S--SNTQPLLMTSWNIPTAEGSQFPISTTINVPTSNEMETETLHLVPGPLSTFTASQTGL 1929
            S  SN+ P+ +++    T  GS      T  +P +  ++T TL    G  S  T      
Sbjct: 4664 SRLSNSPPMTISTHMTTTQTGSS---GATSKIPLA--LDTSTLETSAGTPSVVTEGFAH- 4717

Query: 1930 VSKDVMAMSSIPMSGILPNHGLSENPSLSTSLRAITSTLADVKHTFEKMTTSVTPGTTLP 1989
             SK   AM++        N    +  S  +S   +  T       F     S +   ++ 
Sbjct: 4718 -SKITTAMNNDVKDVSQTNPPFQDEASSPSSQAPVLVTTLPSSVAFTPQWHSTSSPVSMS 4776

Query: 1990 SILSGATSGSVISKSPILTWLLSSLPSGSPPATVSNAPHVMTSSTVEVSKSTFLTSDMIS 2049
            S+L   TS  V +   + T L           TV+++P  M+++  ++S ++  T+D+ +
Sbjct: 4777 SVL---TSSLVKTAGKVDTSL----------ETVTSSPQSMSNTLDDISVTSAATTDIET 4823

Query: 2050 AHP-----FTNLTTLPSATMSTILTRTIPTP---TLGGITTGFPTSLPMSINVTDDIVYI 2101
             HP      TN+ T  SA  S       P P   T   +TT       +S ++       
Sbjct: 4824 THPSINTVVTNVGTTGSAFESHSTVSAYPEPSKVTSPNVTTSTMEDTTISRSIPKSSKTT 4883

Query: 2102 STHPEASSRTTITANPRTVSHPSSFSRKTMS---PSTTDHTLSVGAMPLPSSTITS---- 2154
             T  E +S  T      ++S   + S +T +      T  T  V    + SS+ TS    
Sbjct: 4884 RTETETTSSLTPKLRETSISQEITSSTETSTVPYKELTGATTEVSRTDVTSSSSTSFPGP 4943

Query: 2155 --SWNRIPTASSPSTLIIPKPTLDSLLNIMTTTSTVP-GAS----FPL----------IS 2197
              S   +  ++  +T +   P +     I  TT T P GA+    F +          I 
Sbjct: 4944 DQSTVSLDISTETNTRLSTSPIMTESAEITITTQTGPHGATSQDTFTMDPSNTTPQAGIH 5003

Query: 2198 TGVTYPFTATVSSPISSFF--ETTWLD--------STPSFLSTEASTSPTATKSTVSFYN 2247
            + +T+ F+    + + S    + +W          S  SFLS+ A T+P+   ST+    
Sbjct: 5004 SAMTHGFSQLDVTTLMSRIPQDVSWTSPPSVDKTSSPSSFLSSPAMTTPSLISSTLPEDK 5063

Query: 2248 VEMSFSVFVEEPRIPITSVINEFTENSLNSIFQNSEFSLATLETQIKSRDISE 2300
            +    +  +    + IT ++    E   +S+   S  S   L T   S+D  E
Sbjct: 5064 LSSPMTSLLTSGLVKITDILRTRLEPVTSSLPNFSSTSDKILATSKDSKDTKE 5116



 Score =  174 bits (440), Expect = 2e-42
 Identities = 513/2385 (21%), Positives = 889/2385 (37%), Gaps = 432/2385 (18%)

Query: 246  QIDMTT-----PSQITGVKP---QNTAHSSTLLSQSIPIFATDY---TTISYSNTTSPP- 293
            Q+D++T     P  I+G  P   + T+ SS+LLS  +P   +     TT+  S  +SP  
Sbjct: 6483 QLDLSTLTSRVPEYISGTSPPSVEKTSSSSSLLS--LPAITSPSPVPTTLPESRPSSPVH 6540

Query: 294  LETMTAQKILKT--LVDETATFAVDVLSTSSAISLPTQSISIDNTTNSMKKTKSPSSEST 351
            L ++    ++KT  ++   A+   ++ STS  I  PT S  I +T      T    +   
Sbjct: 6541 LTSLPTSGLVKTTDMLASVASLPPNLGSTSHKI--PTTSEDIKDTEKMYPSTNIAVTNVG 6598

Query: 352  KTTKMVEAMAT--EIFQPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFSTIES 409
             TT   E+ ++     +PP  ++ + TS   ++++VST+    S+    +  S FS    
Sbjct: 6599 TTTSEKESYSSVPAYSEPPKVTSPMVTSFNIRDTIVSTSMPGSSEITRIEMESTFSLAHG 6658

Query: 410  TSMSTTPCLKQKSTNTGALPI-STAGQEFIESTAAGTVPWFTVEKTSPASTHVGTASSFP 468
                       K T+T   PI ST     +     G       E  S   T +       
Sbjct: 6659 L----------KGTSTSQDPIVSTEKSAVLHKLTTGATETSRTEVASSRRTSIPGPDHST 6708

Query: 469  PEPVLISTAAPVDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTR----LIETTPAPRTAE 524
              P + +   P             L  T+        ++T+ TR    L  T+    T +
Sbjct: 6709 ESPDISTEVIP--------SLPISLGITESS------NMTIITRTGPPLGSTSQGTFTLD 6754

Query: 525  TELTSTNFQDVSLPRVE---DAMSTSMSKETSSKTFSFLTSFSFTGTESVQTVIDAEATR 581
            T  TS+     S+   E     M+T M+K+                 E +   I     +
Sbjct: 6755 TPTTSSRAGTHSMATQEFPHSEMTTVMNKDP----------------EILSWTIPPSIEK 6798

Query: 582  TALTPEITLASTVAETMLSSTITGRVYTQNTPTADGHLLTLMSTRSASTSKAPESGPTST 641
            T+ +  +  +  +    +SST+   ++T  +P     + +L++     T+    + P  T
Sbjct: 6799 TSFSSSLMPSPAMTSPPVSSTLPKTIHTTPSP-----MTSLLTPSLVMTTDTLGTSPEPT 6853

Query: 642  TDEAAHLFSSNETIWTSRPDQALLASMNTTTILTFVPNENFTSAFHENTTYTEYLSATTN 701
            T    +L S++  I T+  D   + +M+ +T  T   N   TS+ H + +     S  T 
Sbjct: 6854 TSSPPNLSSTSHEILTTDEDTTAIEAMHPSTS-TAATNVETTSSGHGSQSSVLADSEKTK 6912

Query: 702  IT-PLKA-SPEGKGTTANDATTARYTTAVSKLTSPWFANFSIVSGT--TSITNMPEFKL- 756
             T P+   S  G  T +   + +  TT + + ++     +S+  G   TSI+    F   
Sbjct: 6913 ATAPMDTTSTMGHTTVSTSMSVSSETTKIKREST-----YSLTPGLRETSISQNASFSTD 6967

Query: 757  TTLLLKTIPMSTKPA-----------NELPLTPRETVVPSVDIISTLACIQPNFSTEESA 805
            T+++L  +P  T                +P   + TV+P +    T+  +  + +  ESA
Sbjct: 6968 TSIVLSEVPTGTTAEVSRTEVTSSGRTSIPGPSQSTVLPEIST-RTMTRLFASPTMTESA 7026

Query: 806  SETTQTEINGAIVFGGTTTPVPKSATTQRLNATVTRKEATSHYLMRKSTIAAVAEVSPFS 865
              T  T+   +    G+T     S  T  L+ + T+ +A +H     ST+      S  +
Sbjct: 7027 EMTIPTQTGPS----GST-----SQDTLTLDTSTTKSQAKTH-----STLTQRFPHSEMT 7072

Query: 866  TMLE--VTDESAQRVTASVTVSSFPDIEKL----STPLDNKTATTEVRESWL-LTKLVKT 918
            T++     D S Q   +    SS P +  L    S P  + T    +  S L +T L+ +
Sbjct: 7073 TLMSRGPGDMSWQSSPSLENPSSLPSLLSLPATTSPPPISSTLPVTISSSPLPVTSLLTS 7132

Query: 919  TPRSSYNEMTEMFNFNHTYVAHWTSETSEGISAGSPTSGSTHIFGEPLGASTTRISETSF 978
            +P ++    T+M +            TS  +   SP   S H   E L    T   +T+ 
Sbjct: 7133 SPVTT----TDMLH------------TSPELVTSSPPKLS-HTSDERL----TTGKDTTN 7171

Query: 979  STTPTDRTATSLSDGILPPQPTAAHSSATPVPVTHMFSLPVNGSSVVAEETEVTMSEPST 1038
            +      T T+ S+  +P     + SSA     T   + P+  +S   E+T V +S P  
Sbjct: 7172 TEAVHPSTNTAASNVEIPSSGHESPSSALADSETSKATSPMFITST-QEDTTVAISTPHF 7230

Query: 1039 LARAFSTSVLSDVSNLSSTTMTTALVPPLDQTASTTIVIVPTHGDLIRTTSEATVISVRK 1098
            L          + S +   ++++ L P L +T S+              TS A   S   
Sbjct: 7231 L----------ETSRIQKESISS-LSPKLRETGSSV------------ETSSAIETSAVL 7267

Query: 1099 TSMAVPSLTETPFHSLRLSTPVTAKAETTLFSTSVDTVTP--STHTLVCSKPPPDNIPPA 1156
            + +++ + TE         T VT+ + T++  ++  T+ P  ST   +   P    +  +
Sbjct: 7268 SEVSIGATTEIS------RTEVTSSSRTSISGSAESTMLPEISTTRKIIKFPTSPILAES 7321

Query: 1157 SSTHVISTTSTPEATQPISQVEETSTY-ALSFPYTFSGGGVVASLATGTTETSVVDETTP 1215
            S   + + TS P +T   +   +TST  +L   ++     +  S  T        D   P
Sbjct: 7322 SEMTIKTQTSPPGSTSESTFTLDTSTTPSLVITHSTMTQRLPHSEITTLVSRGAGDVPRP 7381

Query: 1216 SHISANKLTTSVNSHISSSATYRVHTPVSIQLVTSTSVLSSDKDQMTISLGKTP---RTM 1272
            S +   + T+  +S +S SA       +S   V+ST   SS     +++   TP   +T 
Sbjct: 7382 SSLPVEE-TSPPSSQLSLSAM------ISPSPVSSTLPASSHSSSASVTSLLTPGQVKTT 7434

Query: 1273 EVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSPSEIPLGTPSDGNLASSP 1332
            EV + S    +    S  + S+E+  T    T     H   + +   +GT S G+ + S 
Sbjct: 7435 EVLDASAEPETSSPPSLSSTSVEILATSEVTTDTEKIHPFSNTAVTKVGTSSSGHESPSS 7494

Query: 1333 TSGSTQITPTLTSSNTVGVHIPEMSTSLGKTALPSQALTITTFLCPEKESTSAL-PAYTP 1391
                ++ T   ++  T+ +    M  +   T  P+ + T      P    T+ L    T 
Sbjct: 7495 VLPDSETTKATSAMGTISI----MGDTSVSTLTPALSNTRKIQSEPASSLTTRLRETSTS 7550

Query: 1392 RTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINTTFSHLHSLRTQPEVTSV 1451
                +   +  V   VS G  T    T   S +R S      +T S   S+ T P + S 
Sbjct: 7551 EETSLATEANTVLSKVSTGATTEVSRTEAISFSRTSMSGPEQSTMSQDISIGTIPRI-SA 7609

Query: 1452 ASFISES------TQTFPESLSLSTAGLYNDGFTV----LSDRITTAFSVPNVPTMLPRE 1501
            +S ++ES      TQT P   +L +    N   T         +   F  P + T + R 
Sbjct: 7610 SSVLTESAKMTITTQTGPSESTLESTLNLNTATTPSWVETHSIVIQGFPHPEMTTSMGRG 7669

Query: 1502 SSMAT--STPIYQMSS---LPVNVTAFTSKKVSDTP--------PIVITK------SSKT 1542
                +  S P  + +S    P+++ A TS     T         P+ +T       ++ T
Sbjct: 7670 PGGVSWPSPPFVKETSPPSSPLSLPAVTSPHPVSTTFLAHIPPSPLPVTSLLTSGPATTT 7729

Query: 1543 MHPGCLKSPCTATSGPMSEMS------------SIPVNNSAFTPATVSSDTSTRVGLFST 1590
               G    P T++S  +S  S            +  V+ S  T  T  + TS+     S+
Sbjct: 7730 DILGTSTEPGTSSSSSLSTTSHERLTTYKDTAHTEAVHPSTNTGGTNVATTSSGYKSQSS 7789

Query: 1591 LLSSVTPR-TTMTM-QTSTLDVTPVIYAGATSKNKMVSS-------AFTTEMIEAPSRIT 1641
            +L+  +P  TT TM  TS L  TP        + ++ SS       +  +E   + ++++
Sbjct: 7790 VLADSSPMCTTSTMGDTSVLTSTPAFLETRRIQTELASSLTPGLRESSGSEGTSSGTKMS 7849

Query: 1642 PTTFLSPTEPTLPFVKTVPTTIMA---GIVTPFVGTTAFSPLSSKS--TGAISSIPKTTF 1696
                  PT  T    K   T+I       ++P + T   S  S+    T +      T  
Sbjct: 7850 TVLSKVPTGATTEISKEDVTSIPGPAQSTISPDISTRTVSWFSTSPVMTESAEITMNTHT 7909

Query: 1697 SPFLSATQQSSQADEATTLGILSGITNRSLSTVNSGTGVALTDTYSRITVPENM--LSPT 1754
            SP  + TQ +S  D ++T  +       + ST++ G   +   T  R   PE++  +SP 
Sbjct: 7910 SPLGATTQGTSTLDTSSTTSL-----TMTHSTISQGFSHSQMSTLMR-RGPEDVSWMSPP 7963

Query: 1755 HADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLLEK--TSLTNYAT 1812
              +    SF++  SP+ TS      P+    T     SS+   +TSLL       T+   
Sbjct: 7964 LLEKTRPSFSLMSSPATTS------PSPVSSTLPESISSSPLPVTSLLTSGLAKTTDMLH 8017

Query: 1813 SLNTPVSYPPWTPSSATLPSLTSFVYSPHSTEAEISTPKTSPPPTSQMVEFP-------- 1864
              + PV+  P   SS ++  L +       +E    T KT P     + +          
Sbjct: 8018 KSSEPVTNSPANLSSTSVEILAT-------SEVTTDTEKTHPSSNRTVTDVGTSSSGHES 8070

Query: 1865 ---VLGTRMTSSNTQPLLMTSWNIPTAEGSQFPISTTINVPTSNEMETETLHLVPGPLST 1921
               VL    TS  T P+++TS    T E +    ST     TS      T  L  G   T
Sbjct: 8071 TSFVLADSQTSKVTSPMVITS----TMEDTSVSTSTPGFFETSRIQTEPTSSLTLGLRKT 8126

Query: 1922 FTASQTGLVSKDVMAMSSIPMSGILPNHGLSENPSLSTSLRAITSTLADVKHTFEKMTTS 1981
             ++  T L ++    +S +P              +   S   +TS+       F ++T  
Sbjct: 8127 SSSEGTSLATEMSTVLSGVPTGA-----------TAEVSRTEVTSSSRTSISGFAQLT-- 8173

Query: 1982 VTPGTTLPSILSGATSGSVISKSPILTWLLSSLPSGSPPAT----VSNAPH-VMTSSTVE 2036
            V+P T+  +I    TS  +   + ++    +  P  +P +T    +S  P+ V T STV 
Sbjct: 8174 VSPETSTETITRLPTSSIMTESAEMMIKTQTDPPGSTPESTHTVDISTTPNWVETHSTVT 8233

Query: 2037 VSKSTFLTSDMISAHPFTNL--------TTLPSATMSTILTRTIPTPTLGGITTGFPT-S 2087
               S    + ++S  P   L         T  ++++ ++   T P+P    +   FP+ S
Sbjct: 8234 QRFSHSEMTTLVSRSPGDMLWPSQSSVEETSSASSLLSLPATTSPSPVSSTLVEDFPSAS 8293

Query: 2088 LPMS------INVTDDIVYISTHPEASSRTTITA-------------------------- 2115
            LP++      + +T D + IS  P  SS + +++                          
Sbjct: 8294 LPVTSLLNPGLVITTDRMGISREPGTSSTSNLSSTSHERLTTLEDTVDTEDMQPSTHTAV 8353

Query: 2116 -NPRTV--SHPSSFS-------RKTMSPSTTDHTLSVGAMPL--------------PSST 2151
             N RT    H S  S        K  SP  T +T+   ++ +              P+S+
Sbjct: 8354 TNVRTSISGHESQSSVLSDSETPKATSPMGTTYTMGETSVSISTSDFFETSRIQIEPTSS 8413

Query: 2152 ITS------SWNRIPTASSPSTLIIPKPT----------------------------LDS 2177
            +TS      S  RI +A+  ST++   P+                             D 
Sbjct: 8414 LTSGLRETSSSERISSATEGSTVLSEVPSGATTEVSRTEVISSRGTSMSGPDQFTISPDI 8473

Query: 2178 LLNIMTTTSTVP--------GASFPLISTGVTYPFTATVSSPISSFFETTWLDSTPSFLS 2229
                +T  ST P          +    S G T   T T+ +  ++F+  T   ++P F  
Sbjct: 8474 STEAITRLSTSPIMTESAESAITIETGSPGATSEGTLTLDTSTTTFWSGTHSTASPGFSH 8533

Query: 2230 TEASTSPTATKSTVSFYNVEMSFSVFVEEPRIPITSVINEFTENSLNSIFQNSEFSLATL 2289
            +E +T  + T   V +             P +P     +    +SL+S    S    +TL
Sbjct: 8534 SEMTTLMSRTPGDVPW-------------PSLPSVEEASS-VSSSLSSPAMTSTSFFSTL 8579

Query: 2290 ETQIKSRDISEEEMVMDRAILEQREGQEMATISYVPYSCVCQVIIKASSSLASSELMRKI 2349
               I     S    V     L   +  +M   S  P +     +   S+ + ++  + K 
Sbjct: 8580 PESIS----SSPHPVTALLTLGPVKTTDMLRTSSEPETSSPPNLSSTSAEILATSEVTKD 8635

Query: 2350 KSKIHGNFTHGNFTQDQLTLLVNCEHVAVKKLEPGNCKADETASK 2394
            + KIH +           T +VN   V  K L P +  AD   +K
Sbjct: 8636 REKIHPSSN---------TPVVNVGTVIYKHLSPSSVLADLVTTK 8671



 Score =  166 bits (421), Expect = 3e-40
 Identities = 502/2296 (21%), Positives = 855/2296 (37%), Gaps = 377/2296 (16%)

Query: 215  VNKIIPTVDRTLRCFVPENMTIQEKSTTVSQQIDMTTPSQITGVKPQNTAHSSTLLSQSI 274
            +N ++  V  T   F        E  +TVS   +   PS++T      +    T +S+SI
Sbjct: 4828 INTVVTNVGTTGSAF--------ESHSTVSAYPE---PSKVTSPNVTTSTMEDTTISRSI 4876

Query: 275  PIFATDYTTISYSNTTS---PPL-ETMTAQKI----------LKTLVDETATFAVDVLST 320
            P   +  TT + + TTS   P L ET  +Q+I           K L   T   +   +++
Sbjct: 4877 P--KSSKTTRTETETTSSLTPKLRETSISQEITSSTETSTVPYKELTGATTEVSRTDVTS 4934

Query: 321  SSAISLP-----TQSISIDNTTNSMKKTKSPSSESTKTTKMVE-----AMATEIF----- 365
            SS+ S P     T S+ I   TN+   T    +ES + T   +     A + + F     
Sbjct: 4935 SSSTSFPGPDQSTVSLDISTETNTRLSTSPIMTESAEITITTQTGPHGATSQDTFTMDPS 4994

Query: 366  --QPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFSTIESTSMSTTPCLKQKST 423
               P    +   T  F++  V +  S I    + T   S+  T   +S  ++P +   S 
Sbjct: 4995 NTTPQAGIHSAMTHGFSQLDVTTLMSRIPQDVSWTSPPSVDKTSSPSSFLSSPAMTTPSL 5054

Query: 424  NTGALPISTAGQEFIESTAAGTVPWFTVEKT--SPASTHVGTASSFPPEPVLISTAAPVD 481
             +  LP             +G V    + +T   P ++ +   SS   + +L ++    D
Sbjct: 5055 ISSTLPEDKLSSPMTSLLTSGLVKITDILRTRLEPVTSSLPNFSS-TSDKILATSKDSKD 5113

Query: 482  S--VFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETTPAPRTAETELTSTNFQDVSLPR 539
            +  +FP   T      T++K   + H           + +P  A++E      Q V    
Sbjct: 5114 TKEIFPSINT----EETNVKANNSGHE----------SHSPALADSETPKATTQMVITTT 5159

Query: 540  VED-AMSTSMSKETSSKTFSFLTSFSFTGTESVQTVIDAEATRTALTPEITLASTVAETM 598
            V D A STSM    SS+T         T  +   T       R   T + +   T    +
Sbjct: 5160 VGDPAPSTSMPVHGSSET---------TNIKREPTYFLTPRLRETSTSQESSFPTDTSFL 5210

Query: 599  LSSTITGRVYTQNTPTADGHLLTLMSTRSASTSKAPESGPTSTTDEAAHLFSSNETIWTS 658
            LS   TG +   ++   +    + +ST     S  P   P + T E   +F+S+      
Sbjct: 5211 LSKVPTGTITEVSSTGVNSS--SKISTPDHDKSTVP---PDTFTGEIPRVFTSS------ 5259

Query: 659  RPDQALLASMNTTTILTFVPNENFTSAFHENTTYTEYLSATTNITPLKASPEGKGTTAND 718
               +   A M  TT  +  P E+ + +     T T      T+ T  +  P  + TT   
Sbjct: 5260 --IKTKSAEMTITTQAS--PPESASHSTLPLDTSTTLSQGGTHSTVTQGFPYSEVTTLMG 5315

Query: 719  ATTARYTTAVSKLTSPWFANFSIVSGTTSITNMPEFKLTTLLLKTIPMSTKPANELPLT- 777
                     VS +T+P     S VS   S+ + P     + +  T P S  P++ LP+T 
Sbjct: 5316 MGPGN----VSWMTTPPVEETSSVS---SLMSSPAMTSPSPVSSTSPQSI-PSSPLPVTA 5367

Query: 778  -PRETVVPSVDIIST-----LACIQPNFS--TEESASETTQTEINGAIVFGGTTTPVPKS 829
             P   +V + D++ T     +    PN S  T E  +    T    A +   T T V   
Sbjct: 5368 LPTSVLVTTTDVLGTTSPESVTSSPPNLSSITHERPATYKDTAHTEAAMHHSTNTAVTNV 5427

Query: 830  ATT---QRLNATVTRKEATSHYLMRKSTIAAVAEVSPFSTMLEVTDESAQRVTASVTVSS 886
             T+    +  ++V     TS      ST + + + S  ++   ++     ++    T S 
Sbjct: 5428 GTSGSGHKSQSSVLADSETSKATPLMSTTSTLGDTSVSTSTPNIS--QTNQIQTEPTASL 5485

Query: 887  FPDIEKLSTPLDNKTATTEVRESWLLTKLVKTTPRSSYNEMTEMFNFNHTYVAHWTSETS 946
             P + + ST  +  ++TTE   ++        T  S     TE+ + + T ++     T 
Sbjct: 5486 SPRLRESSTS-EKTSSTTETNTAFSYVPTGAITQAS----RTEI-SSSRTSISDLDRPT- 5538

Query: 947  EGISAGSPTSGSTHIFGEPLGASTTRISETSFSTTPTDRTATSLSDGILPPQPT------ 1000
              I+    T   T +F  P+   +  ++ T+ +TTP      + S GILP   +      
Sbjct: 5539 --IAPDISTGMITRLFTSPIMTKSAEMTVTTQTTTP-----GATSQGILPWDTSTTLFQG 5591

Query: 1001 AAHSSATP-VPVTHMFSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTM 1059
              HS+ +   P + + +L       V+  T   + E S+     S S+ S  S +SST+ 
Sbjct: 5592 GTHSTVSQGFPHSEITTLRSRTPGDVSWMTTPPVEETSSGFSLMSPSMTSP-SPVSSTSP 5650

Query: 1060 TTALVPPLDQTASTTIVIVPTHGDLIRTTSEATVIS----------VRKTSMAVPSLTET 1109
             +    PL  TA  T V+V T  +++ TTS   V S           R T+    + TE 
Sbjct: 5651 ESIPSSPLPVTALLTSVLVTT-TNVLGTTSPEPVTSSPPNLSSPTQERLTTYKDTAHTEA 5709

Query: 1110 PFHSLRLSTPVTAKAETTLFSTSVDTVTPSTHTLVCSKPPPDNIPPASSTHVISTTSTPE 1169
               S+  +T V     +     S  +V   +HT   + P         ++    +TSTP 
Sbjct: 5710 MHASMHTNTAVANVGTSISGHESQSSVPADSHTSKATSPMGITFAMGDTS---VSTSTPA 5766

Query: 1170 ATQPISQVEETSTYALSFPYTFSGGGVVASLATGTTETSVVDETTPSHISANKLTTSVNS 1229
              +   Q E TS+       T +   +     T T   S V  TT + +S  ++ TS  +
Sbjct: 5767 FFETRIQTESTSSLIPGLRDTRTSEEINTVTETSTV-LSEVPTTTTTEVSRTEVITSSRT 5825

Query: 1230 HISSSATYRVHTPVSIQLVT--STSVLSSDKDQMTI--------SLGKTPRTMEVTEMSP 1279
             IS     ++   +S + +T  ST    +   +M I        ++ +   T++ +  + 
Sbjct: 5826 TISGPDHSKMSPYISTETITRLSTFPFVTGSTEMAITNQTGPIGTISQATLTLDTSSTAS 5885

Query: 1280 SKNSFISYSRGTPSLEMTDTGFPETTKI------SSHQTHSPSE-IPLGTPSDGNLASSP 1332
             + +    ++  P  E T T    T  +      S  +T SPS  +PL   +  +   S 
Sbjct: 5886 WEGTHSPVTQRFPHSEETTTMSRSTKGVSWQSPPSVEETSSPSSPVPLPAITSHSSLYSA 5945

Query: 1333 TSGST-----QITPTLTSSNTVGVHIPEMSTSLGKTALPSQALTITTFLCPEKESTSALP 1387
             SGS+      +T  LTS     + + +  + L  ++LPS +      L  E  + +   
Sbjct: 5946 VSGSSPTSALPVTSLLTSGRRKTIDMLDTHSELVTSSLPSASSFSGEILTSEASTNTETI 6005

Query: 1388 AYTPRTVEMIVNSTYVTH----SVSYGQDTS---------------FVDTTTSSSTRISN 1428
             ++  T E  + +T   H    SVS     S                V T+T  S    N
Sbjct: 6006 HFSENTAETNMGTTNSMHKLHSSVSIHSQPSGHTPPKVTGSMMEDAIVSTSTPGSPETKN 6065

Query: 1429 PMDINTTFSHLHSLRTQPEVTSVASFISESTQTFPESLSLSTAGLYNDGFTVLSDRITTA 1488
             +D ++T S L     +     V +  +ES   F  S+SL       D  T +S    T 
Sbjct: 6066 -VDRDST-SPLTPELKEDSTALVMNSTTESNTVF-SSVSL-------DAATEVSRAEVTY 6115

Query: 1489 FSVPNVPTMLPRESSMATSTPIYQMSSLPVNVTAFTSKKVSDTPPIVITKSSKTMHPGCL 1548
            +     PT +P  S+ +T +P         +++   S   S++PP+ I+ + KT+     
Sbjct: 6116 YD----PTFMP-ASAQSTKSP---------DISPEASSSHSNSPPLTIS-THKTI--ATQ 6158

Query: 1549 KSPCTATSGPMSEMSSIPVNNSAFTPATVSSDTSTRVGLFSTLLSSVTPRTTMTMQTSTL 1608
              P   TS     + +  +  SA TP+  + D              V   TT  M     
Sbjct: 6159 TGPSGVTSLGQLTLDTSTIATSAGTPSARTQD-------------FVDSETTSVMNNDLN 6205

Query: 1609 DVTPVIYAGATSKNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTLPFVKTVPTTIMAGI- 1667
            DV       A   N + S A    +  +PS +T +T    +  +L  V +VPT  +A I 
Sbjct: 6206 DVLKTSPFSAEEANSLSSQA-PLLVTTSPSPVT-STLQEHSTSSLVSVTSVPTPTLAKIT 6263

Query: 1668 -VTPFVGTTAFSPLSSKSTGAISSIPK-----------------TTFSP--FLSATQQSS 1707
             +   +     SP + ++T A S                     TT SP  F       S
Sbjct: 6264 DMDTNLEPVTRSPQNLRNTLATSEATTDTHTMHPSINTAVANVGTTSSPNEFYFTVSPDS 6323

Query: 1708 QADEATTLGILSGITNRSLSTVNSGTGVALTDTYSRIT---------------VPENMLS 1752
               +AT+  +++  +  S+ + +     A+    S  T               +  +  +
Sbjct: 6324 DPYKATSAVVITSTSGDSIVSTSMPRSSAMKKIESETTFSLIFRLRETSTSQKIGSSSDT 6383

Query: 1753 PTHADSLHTSFNIQV------SPSLTSFKSASGPTKNVKTTTNCFS--SNTRKMTSLLEK 1804
             T  D   T+   +V      S S TS +    PT +  T+T   +  S    +T   E+
Sbjct: 6384 STVFDKAFTAATTEVSRTELTSSSRTSIQGTEKPTMSPDTSTRSVTMLSTFAGLTKSEER 6443

Query: 1805 TSLTNYATSLNTPVSYPPWTPSSAT-----------------LPSLTSFV------YSPH 1841
            T  T       T      W  S  T                 L +LTS V       SP 
Sbjct: 6444 TIATQTGPHRATSQGTLTWDTSITTSQAGTHSAMTHGFSQLDLSTLTSRVPEYISGTSPP 6503

Query: 1842 STEAEIST---------PKTSPPPTSQMVEFPVLGTRMTSSNTQPLLMTSWNIPTAEGSQ 1892
            S E   S+            SP PT+     P     +TS  T  L+ T+  + +     
Sbjct: 6504 SVEKTSSSSSLLSLPAITSPSPVPTTLPESRPSSPVHLTSLPTSGLVKTTDMLASVASLP 6563

Query: 1893 FPI-STTINVPTSNE--METETLHLVPGPLSTFTASQTGLVSKDVMAMSSIPMSGILPNH 1949
              + ST+  +PT++E   +TE ++    P +    +  G  + +  + SS+P        
Sbjct: 6564 PNLGSTSHKIPTTSEDIKDTEKMY----PSTNIAVTNVGTTTSEKESYSSVP-------- 6611

Query: 1950 GLSENPSLSTSLRA---ITSTLADVKHTFEKMTTSVTPGTTLPSILSGATSGSVISKSPI 2006
              SE P +++ +     I  T+           T +   +T    L+    G+  S+ PI
Sbjct: 6612 AYSEPPKVTSPMVTSFNIRDTIVSTSMPGSSEITRIEMESTFS--LAHGLKGTSTSQDPI 6669

Query: 2007 LTW----LLSSLPSGSPPATVSNAPHVMTSSTVEV------SKSTFLTSDMISAHPFTNL 2056
            ++     +L  L +G   AT ++   V +S    +      ++S  +++++I + P  +L
Sbjct: 6670 VSTEKSAVLHKLTTG---ATETSRTEVASSRRTSIPGPDHSTESPDISTEVIPSLPI-SL 6725

Query: 2057 TTLPSATMSTILTRTIP---TPTLGGITTGFPTSLPMSINVTDDIVYISTHPEASSRTTI 2113
                S+ M TI+TRT P   + + G  T   PT+   S       +     P +   T +
Sbjct: 6726 GITESSNM-TIITRTGPPLGSTSQGTFTLDTPTT---SSRAGTHSMATQEFPHSEMTTVM 6781

Query: 2114 TANPRTVSHPSSFSRKTMSPSTTDHTLSVGAMPLPSSTITSSWNRIP----TASSPSTLI 2169
              +P  +S        T+ PS    + S   MP P+ T     + +P    T  SP T +
Sbjct: 6782 NKDPEILSW-------TIPPSIEKTSFSSSLMPSPAMTSPPVSSTLPKTIHTTPSPMTSL 6834

Query: 2170 I--------------PKPTLDSLLNIMTTTSTVPGASFPLISTGVTYPFTATVSSPISSF 2215
            +              P+PT  S  N+ +T+  +        +    +P T+T ++ + + 
Sbjct: 6835 LTPSLVMTTDTLGTSPEPTTSSPPNLSSTSHEILTTDEDTTAIEAMHPSTSTAATNVET- 6893

Query: 2216 FETTWLDSTPSFLSTEASTSPTA---TKSTVSFYNVEMSFSVFVEEPRIPITSVINEFTE 2272
              ++   S  S L+    T  TA   T ST+    V  S SV  E  +I   S  +    
Sbjct: 6894 -TSSGHGSQSSVLADSEKTKATAPMDTTSTMGHTTVSTSMSVSSETTKIKRESTYSLTPG 6952

Query: 2273 NSLNSIFQNSEFSLAT 2288
                SI QN+ FS  T
Sbjct: 6953 LRETSISQNASFSTDT 6968



 Score =  162 bits (411), Expect = 4e-39
 Identities = 483/2207 (21%), Positives = 838/2207 (37%), Gaps = 284/2207 (12%)

Query: 264  AHSSTLLSQSIPIFAT--------DYTTISYSNTTSPPLETMTAQKILKTLVDETATFAV 315
            A +ST+ + +IP   T        +    + S+  +P + T    + + T      T  +
Sbjct: 317  ARASTMPNSAIPFSMTLSNAETSAERVRSTISSLGTPSISTKQTAETILTFHAFAET--M 374

Query: 316  DVLSTSSAISLPTQSI----SIDNTTNSMKKTKSPS----SESTKTTKMVEAMATE--IF 365
            D+ ST  A +L ++ +    ++  T+ S   T SPS    SE T T        TE  + 
Sbjct: 375  DIPSTHIAKTLASEWLGSPGTLGGTSTSALTTTSPSTTLVSEETNTHHSTSGKETEGTLN 434

Query: 366  QPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFSTIESTSMSTTPCLKQKSTNT 425
               TP   L TS   + S ++ T  + +    T  + + S  + +S   T  L+   + +
Sbjct: 435  TSMTP---LETSAPGEESEMTAT-LVPTLGFTTLDSKIRSPSQVSSSHPTRELRTTGSTS 490

Query: 426  GALPISTAGQ---EFIESTAAGT--VPWFTVEKTS-----PASTH-VGTASSFPPE--PV 472
            G    STA     + + +T + T     +T E T+     P  T  V T+ S   E  P 
Sbjct: 491  GRQSSSTAAHGSSDILRATTSSTSKASSWTSESTAQQFSEPQHTQWVETSPSMKTERPPA 550

Query: 473  LISTAAPVDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETTPAPRTAETEL-TSTN 531
              S AAP+ +  P   + F    T       +   +  T + E+T  P T +  + T  +
Sbjct: 551  STSVAAPITTSVPSVVSGFTTLKTSSTKGIWLEETSADTLIGESTAGPTTHQFAVPTGIS 610

Query: 532  FQDVSLPRVEDAMSTSMSKET-SSKTFSFLTSFSFTGTESVQTVIDAEATRTALTPEITL 590
                S  R     +  +++ T SS+T + LT      T  V   +    ++TA       
Sbjct: 611  MTGGSSTRGSQGTTHLLTRATASSETSADLT----LATNGVPVSVSPAVSKTAAGSSPPG 666

Query: 591  ASTVAETMLSSTITGRVYTQNTPTADGHLLTL--MSTRSASTSKAPESGPTSTTDEAAHL 648
             +  + TM+SS I      Q++   +G  L L  ++TR   +S  P+S   +    +  L
Sbjct: 667  GTKPSYTMVSSVIPETSSLQSSAFREGTSLGLTPLNTRHPFSSPEPDSAGHTKISTSIPL 726

Query: 649  FSSNETIWTSRPDQALLASMNTTTILTFVPNENFTSAFHENTTYTEYLSATTNITPLKAS 708
             SS   +     +  + A   T+T        + T+   E +T T+  SA  +   L  +
Sbjct: 727  LSSASVL-----EDKVSA---TSTFSHHKATSSITTGTPEISTKTKPSSAVLSSMTLSNA 778

Query: 709  PEGKGTTANDATTARYTTAVSKLTSPWFANFSIVSGTTSITNM-PEFKLTTLLLKTIPMS 767
                    N  +   + +   + T+      S  + TT   N+ P   LT+   ++    
Sbjct: 779  ATSPERVRNATSPLTHPSPSGEETAGSVLTLSTSAETTDSPNIHPTGTLTSESSESPSTL 838

Query: 768  TKPANELPLTPRETVVPSVDIISTLACIQPNFSTEESASETTQTEINGAIVFGGTTTPV- 826
            + P+     T   +  PS  + ++    +   +   S  ET+ + +   +      TPV 
Sbjct: 839  SLPSVSGVKTTFSSSTPSTHLFTSGEETEETSNPSVSQPETSVSRVRTTLASTSVPTPVF 898

Query: 827  ------PKSATTQRLNATVTRKEATSHYLMRKSTIAAVAEVSPFS--TMLEVTDESAQRV 878
                  P  +     +  V+   ATS   +  ST +A+ ++S  +    +  T+      
Sbjct: 899  PTMDTWPTRSAQFSSSHLVSELRATSSTSVTNSTGSALPKISHLTGTATMSQTNRDTFND 958

Query: 879  TASVTVSSFPDIE-KLSTPLDNKTATTEVRESWLLTKLVK---TTPRSSYNEMTEMFNFN 934
            +A+   +++P+   +  T L + T T     + L   ++    T+P +S  E T +   +
Sbjct: 959  SAAPQSTTWPETSPRFKTGLPSATTTVSTSATSLSATVMVSKFTSPATSSMEATSIREPS 1018

Query: 935  HTYVAHWTSETSEG------------ISAGSPTSGSTHIFGEPLGASTTRISETSF---- 978
             T +   T+ET+ G            I  G  T G       P+G  TT  SETS     
Sbjct: 1019 TTIL---TTETTNGPGSMAVASTNIPIGKGYITEGRLDTSHLPIG--TTASSETSMDFTM 1073

Query: 979  -------------------STTP-----------------TDRTATSLSDGI---LPPQP 999
                               S+TP                 T R  T   DG    L PQ 
Sbjct: 1074 AKESVSMSVSPSQSMDAAGSSTPGRTSQFVDTFSDDVYHLTSREITIPRDGTSSALTPQM 1133

Query: 1000 TAAHSSATPVPVTHMFSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTM 1059
            TA H  +          L +  SS  +   +VTMS   +  R  +TS++ D    S   M
Sbjct: 1134 TATHPPSPDPGSARSTWLGILSSSPSSPTPKVTMSSTFSTQRV-TTSMIMDTVETSRWNM 1192

Query: 1060 TTALVPPLDQTASTTIVIVPTHGDLIRTT-------SEATVISVRK----TSMAVPSLTE 1108
                 P L  T S T   +PT G + ++T       S AT +   +    T    P  T 
Sbjct: 1193 -----PNLPSTTSLTPSNIPTSGAIGKSTLVPLDTPSPATSLEASEGGLPTLSTYPESTN 1247

Query: 1109 TPFHSLRLSTPVTAKAETTLFSTSVDTVTPSTHTLVCSKPPPDNIPPASSTHVISTTSTP 1168
            TP  S+ L    ++++ +T+  T    V P ++T +       +I  +++    S+ S+P
Sbjct: 1248 TP--SIHLGAHASSESPSTIKLTMASVVKPGSYTPLTFPSIETHIHVSTARMAYSSGSSP 1305

Query: 1169 EATQPISQVEETSTYALSFPYTFSGGGVVASLATGTTETSVVDETTPSHISANKLTTSVN 1228
            E T P     ET+T +   P T+          T   +TS    +TP   S   L T+ N
Sbjct: 1306 EMTAP----GETNTGSTWDPTTYI-------TTTDPKDTSSAQVSTPH--SVRTLRTTEN 1352

Query: 1229 SHISSSATYRVHTPVSIQLVTSTSVLSSDKDQMTISLGKTPRT-MEVTEMSPSKNSFISY 1287
               + SAT   ++  S ++ +S ++ S      TI+      T +  T+++   + F + 
Sbjct: 1353 HPKTESATPAAYSG-SPKISSSPNLTSPATKAWTITDTTEHSTQLHYTKLAEKSSGFETQ 1411

Query: 1288 SRGTPSLEMTDTGFPETTKISSHQTHSPSEIP----LGTPSDGNLASSPTSG--STQITP 1341
            S   P         P +  I S      S++P    +  PS+    + P +   ST +T 
Sbjct: 1412 SAPGP----VSVVIPTSPTIGSSTLELTSDVPGEPLVLAPSEQTTITLPMATWLSTSLTE 1467

Query: 1342 TLTSSNTVGVHIPEMSTSLGKTALPSQALTITTFLCPEKESTSALPAYTPRTVE--MIVN 1399
             + S++   + I   S+ +   A+     T +  L   +  TSA+      T++  + + 
Sbjct: 1468 EMASTD---LDISSPSSPMSTFAIFPPMSTPSHELSKSEADTSAIRNTDSTTLDQHLGIR 1524

Query: 1400 STYVTHSVSYGQDTSFVDTTTSSSTRISNPMD-INTTFSHLHSLRTQPEVTSVASFISES 1458
            S   T  ++    T    T TS     +   D ++ T S  H  ++  + TS+ +  S S
Sbjct: 1525 SLGRTGDLTTVPITPLTTTWTSVIEHSTQAQDTLSATMSPTHVTQSLKDQTSIPASASPS 1584

Query: 1459 --TQTFPESLSLSTAGLYNDGFTV--------LSDRITTA-FSVPNVPTMLPRESSMATS 1507
              T+ +PE   L T G  +   T         LS  I T   ++ + P M    +  ++S
Sbjct: 1585 HLTEVYPE---LGTQGRSSSEATTFWKPSTDTLSREIETGPTNIQSTPPMDNTTTGSSSS 1641

Query: 1508 TPIYQMSSLPVNVTA----FTSKKVSDTPPIVITKSSKTMHPGCLKSPCTATSGPMSEMS 1563
                 ++ LP+  ++     T+  +           + TM      +P  + S  +  +S
Sbjct: 1642 GVTLGIAHLPIGTSSPAETSTNMALERRSSTATVSMAGTMGLLVTSAPGRSISQSLGRVS 1701

Query: 1564 SIPVNNSAFTPATVSSDTSTRVGLF--STLLSSVTPRTTMTMQTSTL------DVTPVI- 1614
            S+   ++       S  +S R+     + L SS+ P      Q ST         TP + 
Sbjct: 1702 SVLSESTTEGVTDSSKGSSPRLNTQGNTALSSSLEPSYAEGSQMSTSIPLTSSPTTPDVE 1761

Query: 1615 -YAGATSKNKMVSSAFTTEM------IEAPSRITPTTFLSPTEPT-----LPFVKTVPTT 1662
               G+T   K V++  T+++       E+ S    +T L  TE T           +P+ 
Sbjct: 1762 FIGGSTFWTKEVTTVMTSDISKSSARTESSSATLMSTALGSTENTGKEKLRTASMDLPSP 1821

Query: 1663 IMAGIVTPFVGTTAFSPLSSKSTGAISSIPKTTFSPFLS-ATQQSSQADEATTLGILSGI 1721
              +  VTP++  T            +S+ P TT S  LS     SS    AT   + +G+
Sbjct: 1822 TPSMEVTPWISLT------------LSNAPNTTDSLDLSHGVHTSSAGTLATDRSLNTGV 1869

Query: 1722 TNRSLSTVNSGTGVALTDTYSRITVPENMLSPTHADSLHTSFNIQVSPSLTSFKSASGP- 1780
            T  S   + +G+     DT S+     +M + TH    +T  + +VS S+      S P 
Sbjct: 1870 TRAS--RLENGS-----DTSSKSL---SMGNSTHTSMTYTEKS-EVSSSIHPRPETSAPG 1918

Query: 1781 --TKNVKTTTNCFSSNTRKMTSL----LEKTSLTNYATSLNTPVSYPPWTPSSATLPSLT 1834
              T    T  N   S T   +S+    +  T +T+     + P+++ P TP +    S  
Sbjct: 1919 AETTLTSTPGNRAISLTLPFSSIPVEEVISTGITSGPDINSAPMTHSPITPPTIVWTSTG 1978

Query: 1835 SFVYSP---HSTEAEISTPKTSPPPTSQMVEFPVLGTRMTSSNTQPLLMTSWNIPTAEGS 1891
            +   S    H+  +E  + +T   P    V      T   S ++     + ++  + E  
Sbjct: 1979 TIEQSTQPLHAVSSEKVSVQTQSTPYVNSVAVSASPTHENSVSSGSSTSSPYSSASLESL 2038

Query: 1892 QFPISTTINVPTSNEMETETLHLVPGP---LSTFTASQTGLVSKDVMAMSSIPM-SGILP 1947
               IS    + +     T +L     P   LS   +S    VS      +  P+ S    
Sbjct: 2039 DSTISRRNAITSWLWDLTTSLPTTTWPSTSLSEALSSGHSGVSNPSSTTTEFPLFSAAST 2098

Query: 1948 NHGLSENPSLSTSLRAITSTLADVKHTFEKMTTSVTPGTTLPSILSGATSGSVISKSPIL 2007
            +     NP   T      +T A   +T     T ++      SI S       I+    +
Sbjct: 2099 SAAKQRNPETET--HGPQNTAASTLNTDASSVTGLSETPVGASISSEVPLPMAITSRSDV 2156

Query: 2008 TWLLSSLPSGSPPATVSNAPHVMTSSTVEVSKSTFLTSDMISAHPFTNLTTLPSATMSTI 2067
            + L S   +     T S+A   +T  T+ +  S  L S  ++  P+T   ++P  +  T 
Sbjct: 2157 SGLTSESTANPSLGTASSAGTKLTR-TISLPTSESLVSFRMNKDPWT--VSIPLGSHPTT 2213

Query: 2068 LTRT-IPTPTLG--GITTGFPTSLPMSINVTDDIVYISTHPEASSRTTITANPRTVSH-P 2123
             T T IP  + G  G++T     +    +  + I  +S  P   +  T      T+SH P
Sbjct: 2214 NTETSIPVNSAGPPGLSTVASDVIDTPSDGAESIPTVSFSPSPDTEVT------TISHFP 2267

Query: 2124 SSFSRKTMSPSTTDHTLSVGAMPLPSSTITSSWNRIPTASSPSTLIIPKPTLDSLLNIMT 2183
               +    + S+  H L+    P+P   ++S+ +  PT +SPS  +  + T+ S     T
Sbjct: 2268 EKTTHSFRTISSLTHELTSRVTPIPGDWMSSAMSTKPTGASPSITLGERRTITSA--APT 2325

Query: 2184 TTSTVPGASFPLISTGVTYPFTATVSSPISSFFETTWLDSTPSFLSTEASTS-------- 2235
            T+  V  ASF   ST      T   +S I    +T  L S  S  S   +TS        
Sbjct: 2326 TSPIVLTASFTETSTVSLDNETTVKTSDILDARKTNELPSDSSSSSDLINTSIASSTMDV 2385

Query: 2236 -PTATKSTVSFYNVEMSFSVFV---EEPRIPI-TSVINEFTENSLNS 2277
              TA+ S  S   +  S S  +   + P++P  T+  N  T  S++S
Sbjct: 2386 TKTASISPTSISGMTASSSPSLFSSDRPQVPTSTTETNTATSPSVSS 2432



 Score =  149 bits (377), Expect = 3e-35
 Identities = 476/2172 (21%), Positives = 793/2172 (36%), Gaps = 337/2172 (15%)

Query: 312  TFAVDVLS-TSSAISLPTQSISIDNTTNSMKKTKSPSSESTKTTKMVEAMATEIFQPPTP 370
            TF+ DV   TS  I++P    S    T  M  T  PS +          + +     PTP
Sbjct: 1105 TFSDDVYHLTSREITIPRDGTS-SALTPQMTATHPPSPDPGSARSTWLGILSSSPSSPTP 1163

Query: 371  ----SNFLSTSRFTKNSVVSTTSAIK-SQSAVTKTTSLFSTIESTSMSTTPCLKQKSTNT 425
                S+  ST R T + ++ T    + +   +  TTSL  +   TS +       KST  
Sbjct: 1164 KVTMSSTFSTQRVTTSMIMDTVETSRWNMPNLPSTTSLTPSNIPTSGAIG-----KST-- 1216

Query: 426  GALPISTAGQEFIESTAAGTVPWFTV--EKTSPASTHVGT-ASSFPPEPVLISTAAPVDS 482
              +P+ T         + G +P  +   E T+  S H+G  ASS  P  + ++ A+ V  
Sbjct: 1217 -LVPLDTPSPATSLEASEGGLPTLSTYPESTNTPSIHLGAHASSESPSTIKLTMASVVKP 1275

Query: 483  ------VFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIET-TPAPRTAETELTSTNFQDV 535
                   FP  +T   ++T  M  A++  S    T   ET T +     T +T+T+ +D 
Sbjct: 1276 GSYTPLTFPSIETHIHVSTARM--AYSSGSSPEMTAPGETNTGSTWDPTTYITTTDPKDT 1333

Query: 536  SLPRVEDAMS--TSMSKETSSKTFSFLTSFSFTGTESVQTV--IDAEATRTALTPEITLA 591
            S  +V    S  T  + E   KT S  T  +++G+  + +   + + AT+     + T  
Sbjct: 1334 SSAQVSTPHSVRTLRTTENHPKTES-ATPAAYSGSPKISSSPNLTSPATKAWTITDTTEH 1392

Query: 592  STVAETMLSSTITGRVYTQNTPTADGHLLTLMSTRSASTSK------------APESGPT 639
            ST       +  +    TQ+ P     ++    T  +ST +            AP    T
Sbjct: 1393 STQLHYTKLAEKSSGFETQSAPGPVSVVIPTSPTIGSSTLELTSDVPGEPLVLAPSEQTT 1452

Query: 640  STTDEAAHLFSSNETIWTSRPDQALLASMNTTTILTFVPNENFTSAFHENTTYTEYLSAT 699
             T   A  L +S      S        S   +T   F P    ++  HE +      SA 
Sbjct: 1453 ITLPMATWLSTSLTEEMASTDLDISSPSSPMSTFAIFPP---MSTPSHELSKSEADTSAI 1509

Query: 700  TNITPLKASPEGKGTTANDATTARYTTAVSKLTSPWFA---NFSIVSGTTSITNMPEFKL 756
             N T      +  G  +   T    T  ++ LT+ W +   + +    T S T  P    
Sbjct: 1510 RN-TDSTTLDQHLGIRSLGRTGDLTTVPITPLTTTWTSVIEHSTQAQDTLSATMSPTHVT 1568

Query: 757  TTLLLKT-IPMSTKPANELPLTPR---------ETVV---PSVDIISTLACIQP-NFSTE 802
             +L  +T IP S  P++   + P          E      PS D +S      P N  + 
Sbjct: 1569 QSLKDQTSIPASASPSHLTEVYPELGTQGRSSSEATTFWKPSTDTLSREIETGPTNIQST 1628

Query: 803  ESASETTQTEINGAIVFG------GTTTPVPKSATT--QRLNATVTRKEATSHYLMRKS- 853
                 TT    +  +  G      GT++P   S     +R ++T T   A +  L+  S 
Sbjct: 1629 PPMDNTTTGSSSSGVTLGIAHLPIGTSSPAETSTNMALERRSSTATVSMAGTMGLLVTSA 1688

Query: 854  -------TIAAVAEVSPFSTMLEVTDES----------AQRVTASVTVSSFPDIEKLST- 895
                   ++  V+ V   ST   VTD S               +S    S+ +  ++ST 
Sbjct: 1689 PGRSISQSLGRVSSVLSESTTEGVTDSSKGSSPRLNTQGNTALSSSLEPSYAEGSQMSTS 1748

Query: 896  -PLDNKTATTEVR---ESWLLTKLVKTTPRSSYNEMTEMFNFNHTYVAHWTSETSEGISA 951
             PL +   T +V     S   TK V T   S  ++ +     +   +      ++E    
Sbjct: 1749 IPLTSSPTTPDVEFIGGSTFWTKEVTTVMTSDISKSSARTESSSATLMSTALGSTENTGK 1808

Query: 952  GSPTSGSTHIFGEPLGASTTRISETSFSTTPTDRTATSLSDGILPPQP-TAAHSSATPVP 1010
                + S  +         T     + S  P    +  LS G+      T A   +    
Sbjct: 1809 EKLRTASMDLPSPTPSMEVTPWISLTLSNAPNTTDSLDLSHGVHTSSAGTLATDRSLNTG 1868

Query: 1011 VTHMFSLPVNGSSVVA----------------EETEVTMS---EPSTLARAFSTSVLSDV 1051
            VT    L  NGS   +                E++EV+ S    P T A    T++ S  
Sbjct: 1869 VTRASRLE-NGSDTSSKSLSMGNSTHTSMTYTEKSEVSSSIHPRPETSAPGAETTLTSTP 1927

Query: 1052 SNLSSTTMTTALVPPLDQTASTTIVIVPTHGDLIRTTSEATVISVRKTSMAVPSLTETPF 1111
             N + +        P+++  ST I   P       T S  T  ++  TS      +  P 
Sbjct: 1928 GNRAISLTLPFSSIPVEEVISTGITSGPDINSAPMTHSPITPPTIVWTSTGTIEQSTQPL 1987

Query: 1112 HSLRLSTPVTAKAETTLFSTSVDTVTPSTHTLVCSKPPPDNIPPASST-----HVIS--- 1163
            H++  S  V+ + ++T +  SV      TH    S     + P +S++       IS   
Sbjct: 1988 HAVS-SEKVSVQTQSTPYVNSVAVSASPTHENSVSSGSSTSSPYSSASLESLDSTISRRN 2046

Query: 1164 ---------TTSTPEATQPISQVEET-----------STYALSFPYTFSGGGVVASLATG 1203
                     TTS P  T P + + E            S+    FP   +     A     
Sbjct: 2047 AITSWLWDLTTSLPTTTWPSTSLSEALSSGHSGVSNPSSTTTEFPLFSAASTSAAKQRNP 2106

Query: 1204 TTETSVVDETTPSHIS--ANKLTTSVNSHISSSATYRVHTPVSIQLVTSTSVLSSDKDQM 1261
             TET     T  S ++  A+ +T    + + +S +  V  P++I   +  S L+S+    
Sbjct: 2107 ETETHGPQNTAASTLNTDASSVTGLSETPVGASISSEVPLPMAITSRSDVSGLTSESTAN 2166

Query: 1262 TISLG-------KTPRTMEVTEMSPSKNSFISYSR-----------GTPSLEMTDTGFPE 1303
              SLG       K  RT+ +    P+  S +S+             G+     T+T  P 
Sbjct: 2167 P-SLGTASSAGTKLTRTISL----PTSESLVSFRMNKDPWTVSIPLGSHPTTNTETSIPV 2221

Query: 1304 TTKISSHQTHSPSEIPLGTPSDGNLASSPTSGSTQITPTLTSSNTVGVHIPEMSTSLGKT 1363
             +      +   S++ + TPSDG   S PT      +P+  +  T   H PE +T   +T
Sbjct: 2222 NSAGPPGLSTVASDV-IDTPSDG-AESIPT---VSFSPSPDTEVTTISHFPEKTTHSFRT 2276

Query: 1364 ALPSQALTITTFLCP----------EKESTSALPAYT---PRTVEMIVNSTYVTHSVSYG 1410
             + S    +T+ + P            + T A P+ T    RT+     +T      +  
Sbjct: 2277 -ISSLTHELTSRVTPIPGDWMSSAMSTKPTGASPSITLGERRTITSAAPTTSPIVLTASF 2335

Query: 1411 QDTSFVDTTTSSSTRISNPMDINTTFSHLHSLRTQPEVTSVASFISESTQTFPESLSLST 1470
             +TS V     ++ + S+ +D   T        +  ++ + +  I+ ST    ++ S+S 
Sbjct: 2336 TETSTVSLDNETTVKTSDILDARKTNELPSDSSSSSDLINTS--IASSTMDVTKTASISP 2393

Query: 1471 AGLYNDGFTVLSDRITTAFSVPNVPTMLPRESSMATSTPIYQMSSLPVNVTAFTSKKVSD 1530
              +   G T  S     +   P VPT    E++ ATS P    ++  ++  +      S 
Sbjct: 2394 TSI--SGMTASSSPSLFSSDRPQVPTSTT-ETNTATS-PSVSSNTYSLDGGSNVGGTPST 2449

Query: 1531 TPPIVITKSSKTMHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPATVSSDTSTRVGLFST 1590
             PP  IT      HP    S   A S P+   S++   ++A      SS++         
Sbjct: 2450 LPPFTIT------HPVETSSALLAWSRPVRTFSTMVSTDTASGENPTSSNS--------- 2494

Query: 1591 LLSSVTPRTTMTMQTSTLDVTPVIYAGATSKNKMVSSAFTTEMIEAPSRITPTTFLSPTE 1650
            +++SV    T T   ST D+  + +   +   +  S   +T        I P T  +P  
Sbjct: 2495 VVTSVPAPGTWTSVGSTTDLPAMGFLKTSPAGEAHSLLAST--------IEPATAFTPH- 2545

Query: 1651 PTLPFVKTVPTTIMAGIVTPFVGTTAFSPLSSKSTGAISSIPKTTFSPFLSATQQSSQAD 1710
                        + A +VT    T+  S L++  + AI S P+T  +P   A  ++S   
Sbjct: 2546 ------------LSAAVVTGSSATSEASLLTTSESKAIHSSPQTPTTPTSGANWETSATP 2593

Query: 1711 EATTLGILSGITNRSLSTVNSGTGVALTDTYSRITVPENMLSPTHADSLHTSFNIQVSPS 1770
            E+     L  +T  S +T+ S   V  T  +S ++ P +   P+       SF   +  +
Sbjct: 2594 ES-----LLVVTETSDTTLTSKILVTDTILFSTVSTPPSKF-PSTGTLSGASFPTLLPDT 2647

Query: 1771 LTSFKSASGPTKNVKTTTNCFSSNTRKMTSL--LEKTSLTNYATS-----LNTPVSYPPW 1823
                 +A+ PT ++ T+ +     T    SL  + +T+LT   TS     +   VS P  
Sbjct: 2648 PAIPLTATEPTSSLATSFDSTPLVTIASDSLGTVPETTLTMSETSNGDALVLKTVSNPDR 2707

Query: 1824 TPSSATLPSLTSFVYSPHSTE-AEISTPKTSPPPTSQMVEFPVLGTRMT----------S 1872
            +    T+  +T     P ST  ++I  P+ +    S  V    L    T          +
Sbjct: 2708 SIPGITIQGVTESPLHPSSTSPSKIVAPRNTTYEGSITVALSTLPAGTTGSLVFSQSSEN 2767

Query: 1873 SNTQPLLMTSWNI------PTAEGSQ-FPISTTINVPTSNEMETET-----LHLVPGPLS 1920
            S T  L+ +S  +      P   GSQ    S  I   +++   T+T     L + PG ++
Sbjct: 2768 SETTALVDSSAGLERASVMPLTTGSQGMASSGGIRSGSTHSTGTKTFSSLPLTMNPGEVT 2827

Query: 1921 TFTASQTG-LVSKDVMAMSSIPM------SGILPNHGLSENP-----SLSTS-------L 1961
              +   T  L +    A   IP+      SG+L     S +P     SL+T+        
Sbjct: 2828 AMSEITTNRLTATQSTAPKGIPVKPTSAESGLLTPVSASSSPSKAFASLTTAPPTWGIPQ 2887

Query: 1962 RAITSTLADVKHTFEKMTTSVTPGTTLPSI--LSGATSGSVISKSP-------------- 2005
              +T   ++V     K  +  TPG +L +I     +T+ S +SKSP              
Sbjct: 2888 STLTFEFSEVPSLDTKSASLPTPGQSLNTIPDSDASTASSSLSKSPEKNPRARMMTSTKA 2947

Query: 2006 -----ILTWLLSSLPSGS-PPATVSNAPHVMTSSTVEVSKSTFLTSDMISAHPFTNLTTL 2059
                   +   +  P GS  P+   + P V TS T       + +  M    P    + +
Sbjct: 2948 ISASSFQSTGFTETPEGSASPSMAGHEPRVPTSGT---GDPRYASESMSYPDPSKASSAM 3004

Query: 2060 PSATMSTILTRTIPTPTLGGITTGFPTSLPMSINVTDDIVYISTHPEASSRTTITANPRT 2119
             S ++++ LT    T   G       +S P+S++   +  ++S     S +T++   P  
Sbjct: 3005 TSTSLASKLTTLFST---GQAARSGSSSSPISLSTEKETSFLSPTASTSRKTSLFLGPSM 3061

Query: 2120 VSHPSSFSRKTMSPSTTDHTLSVGAMPLPSSTITSSWNRIPTASSPSTLIIPKPTLDSLL 2179
               P+      +   T+  TLS      P+ST+  S    P  +S  T+   + T     
Sbjct: 3062 ARQPNIL----VHLQTSALTLS------PTSTLNMSQEEPPELTSSQTIAEEEGTTAETQ 3111

Query: 2180 NIMTTTSTVPGASFPLISTGVTYPFTATVSSPISSFFETTWLDSTPSFLSTEASTSPTAT 2239
             +  T S  P +  P+ S   T P     SSP       TW  S    +S  A TS   T
Sbjct: 3112 TLTFTPSETPTSLLPVSSP--TEPTARRKSSP------ETWASS----ISVPAKTSLVET 3159

Query: 2240 KSTVSFYNVEMS 2251
                    ++MS
Sbjct: 3160 TDGTLVTTIKMS 3171



 Score =  144 bits (362), Expect = 2e-33
 Identities = 462/2185 (21%), Positives = 816/2185 (37%), Gaps = 334/2185 (15%)

Query: 249  MTTPSQITGVK-PQNTAHSSTLLSQSIPIFATDYTTISYSNTTSPPLETMTAQKILKTLV 307
            M  PS + G   P  +  + +  +++ P   +  T  + S  TS     +T   +  T  
Sbjct: 1    MLKPSGLPGSSSPTRSLMTGSRSTKATPEMDSGLTGATLSPKTSTGAIVVTEHTLPFTSP 60

Query: 308  DETATFAVDVLSTSSAISLPTQSISIDNTTNSMKKTKSPSSESTKTTKMVEAMATEIFQP 367
            D+T         TSS +   TQS+ + ++      ++  +    +T+  +          
Sbjct: 61   DKTLASP-----TSSVVGRTTQSLGVMSSALPESTSRGMTHSEQRTSPSLSPQVN----- 110

Query: 368  PTPS-NFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFS-TIESTSMSTTPCLKQKSTNT 425
             TPS N+ +TS  +  S   T ++  ++   TK  S ++ T+E+TS   T    +K T  
Sbjct: 111  GTPSRNYPATSMVSGLSSPRTRTS-STEGNFTKEASTYTLTVETTSGPVT----EKYT-- 163

Query: 426  GALPISTAGQEFIESTAAGTVPWFTVEKTSPASTHVGTASSFPPEPVLISTAAPVDSVFP 485
              +P  T+  E   +       +  V+ TSP  T   + +S    PV   +  P ++   
Sbjct: 164  --VPTETSTTEGDSTETPWDTRYIPVKITSPMKTFADSTASKENAPV---SMTPAETTVT 218

Query: 486  RNQTAFPLATTDMKIAFTVHSLTLPTRLIETTPAPRTAETELTSTNFQDVSLPRVEDAMS 545
             + T  P  T           L L  +    +    + E  L++T +   S     +  S
Sbjct: 219  DSHT--PGRTNPSFGTLYSSFLDLSPKGTPNSRGETSLELILSTTGYPFSS----PEPGS 272

Query: 546  TSMSKETSSKTFSFLTSFSFTGTESVQTVIDAEATRTALTPEITLASTVAETMLSSTITG 605
               S+ ++S   S   S       S  ++   ++  + L+P +  A   A TM +S I  
Sbjct: 273  AGHSRISTSAPLSSSASV-LDNKISETSIFSGQSLTSPLSPGVPEAR--ASTMPNSAIPF 329

Query: 606  RVYTQNTPTADGHL---LTLMSTRSASTSKAPESGPT-----STTD-EAAHLFSSNETIW 656
             +   N  T+   +   ++ + T S ST +  E+  T      T D  + H+  +  + W
Sbjct: 330  SMTLSNAETSAERVRSTISSLGTPSISTKQTAETILTFHAFAETMDIPSTHIAKTLASEW 389

Query: 657  TSRPDQALLASMNTTTILTFVPNENF----TSAFHENTTYTEYLSATTNITPLKASPEGK 712
               P    L   +T+ + T  P+       T+  H  +      +  T++TPL+ S  G+
Sbjct: 390  LGSP--GTLGGTSTSALTTTSPSTTLVSEETNTHHSTSGKETEGTLNTSMTPLETSAPGE 447

Query: 713  GT--TANDATTARYTTAVSKLTSPWFANFS---------------------------IVS 743
             +  TA    T  +TT  SK+ SP   + S                           I+ 
Sbjct: 448  ESEMTATLVPTLGFTTLDSKIRSPSQVSSSHPTRELRTTGSTSGRQSSSTAAHGSSDILR 507

Query: 744  GTTSITNMPEFKLT------------TLLLKTIP-MSTK--PANELPLTPRETVVPSVDI 788
             TTS T+      +            T  ++T P M T+  PA+     P  T VPSV  
Sbjct: 508  ATTSSTSKASSWTSESTAQQFSEPQHTQWVETSPSMKTERPPASTSVAAPITTSVPSV-- 565

Query: 789  ISTLACIQPNFSTEESASETTQTEINGAIVFGGTTTPVPKSATTQRLNATVTR-KEATSH 847
            +S    ++ + +      ET+   + G    G TT              + TR  + T+H
Sbjct: 566  VSGFTTLKTSSTKGIWLEETSADTLIGESTAGPTTHQFAVPTGISMTGGSSTRGSQGTTH 625

Query: 848  YLMRKSTIAAVAEVSPFSTMLEVTDESAQRVTASVTVSSFPDIEKL----STPLDNKTAT 903
             L R +   A +E S   T+           T  V VS  P + K     S P   K + 
Sbjct: 626  LLTRAT---ASSETSADLTL----------ATNGVPVSVSPAVSKTAAGSSPPGGTKPSY 672

Query: 904  TEVRESWLLTKLVKTTPRSSYNEMTEM----FNFNHTYVA-HWTSETSEGISAGSPTSGS 958
            T V      T  +++   S++ E T +     N  H + +    S     IS   P   S
Sbjct: 673  TMVSSVIPETSSLQS---SAFREGTSLGLTPLNTRHPFSSPEPDSAGHTKISTSIPLLSS 729

Query: 959  THIFGEPLGASTT----RISETSFSTTPTDRTATSLSDGILPPQPTAAHSSATPVPVTHM 1014
              +  + + A++T    + + +  + TP   T T  S  +L    T ++++ +P  V + 
Sbjct: 730  ASVLEDKVSATSTFSHHKATSSITTGTPEISTKTKPSSAVLSSM-TLSNAATSPERVRNA 788

Query: 1015 FSLPVNGSSVVAEETEVTMSEPSTLARA------FSTSVLSDVSNLSSTTMTTALVPPLD 1068
             S P+   S   EET  ++   ST A          T  L+  S+ S +T++   V  + 
Sbjct: 789  TS-PLTHPSPSGEETAGSVLTLSTSAETTDSPNIHPTGTLTSESSESPSTLSLPSVSGVK 847

Query: 1069 QT--ASTTIVIVPTHGDLIRTTS-------EATVISVRKT--SMAVPS----------LT 1107
             T  +ST    + T G+    TS       E +V  VR T  S +VP+            
Sbjct: 848  TTFSSSTPSTHLFTSGEETEETSNPSVSQPETSVSRVRTTLASTSVPTPVFPTMDTWPTR 907

Query: 1108 ETPFHSLRLSTPVTAKAETTLFSTSVDTVTPSTHTLVCSKPPPDNIPPASSTHVISTTST 1167
               F S  L + + A + T++ +++   +   +H    +     N    + +    +T+ 
Sbjct: 908  SAQFSSSHLVSELRATSSTSVTNSTGSALPKISHLTGTATMSQTNRDTFNDSAAPQSTTW 967

Query: 1168 PEATQPISQVEETSTYALSFPYTFSGGGVVASLATGTTETSVVDETTPSHISANKLTTSV 1227
            PE +        ++T  +S   T     V+ S  T +  TS ++ T+    S   LTT  
Sbjct: 968  PETSPRFKTGLPSATTTVSTSATSLSATVMVSKFT-SPATSSMEATSIREPSTTILTTET 1026

Query: 1228 NSHISSSATYRVHTPVSIQLVT----STSVL-----SSDKDQMTISLGKTPRTMEVTEMS 1278
             +   S A    + P+    +T     TS L     +S +  M  ++ K   +M V   S
Sbjct: 1027 TNGPGSMAVASTNIPIGKGYITEGRLDTSHLPIGTTASSETSMDFTMAKESVSMSV---S 1083

Query: 1279 PSKNSFISYSRGTP--SLEMTDTGFPETTKISSHQ------------------THSPSEI 1318
            PS+ S  +    TP  + +  DT   +   ++S +                  TH PS  
Sbjct: 1084 PSQ-SMDAAGSSTPGRTSQFVDTFSDDVYHLTSREITIPRDGTSSALTPQMTATHPPSPD 1142

Query: 1319 PLGTPSD--GNLASSPTSGSTQITPTLTSSNTVGVHIPEMSTSLGKTALPSQALTITTFL 1376
            P    S   G L+SSP+S     TP +T S+T        ST    T++    +  + + 
Sbjct: 1143 PGSARSTWLGILSSSPSSP----TPKVTMSST-------FSTQRVTTSMIMDTVETSRWN 1191

Query: 1377 CPEKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINTTF 1436
             P   ST++L   TP  +           S + G+ T     T S +T       +  + 
Sbjct: 1192 MPNLPSTTSL---TPSNIPT---------SGAIGKSTLVPLDTPSPAT------SLEASE 1233

Query: 1437 SHLHSLRTQPEVTSVASFI--SESTQTFPESLSLSTAGLYNDGFTVLSDRITTAFSVPNV 1494
              L +L T PE T+  S    + ++   P ++ L+ A +   G         T  + P++
Sbjct: 1234 GGLPTLSTYPESTNTPSIHLGAHASSESPSTIKLTMASVVKPG-------SYTPLTFPSI 1286

Query: 1495 PTMLPRESSMATSTPIYQMSSLPVNVTAFTSKKVSDTPPIVI--------TKSSKTMHPG 1546
             T +     ++T+   Y   S P       +   S   P           T S++   P 
Sbjct: 1287 ETHI----HVSTARMAYSSGSSPEMTAPGETNTGSTWDPTTYITTTDPKDTSSAQVSTPH 1342

Query: 1547 CLKSPCTATSGPMSEMSSIPVNNSAFTPATVSSDTSTRVGLFSTLLSSVTPRTTMTMQTS 1606
             +++  T  + P +E +         TPA  S   S ++     L S  T   T+T   +
Sbjct: 1343 SVRTLRTTENHPKTESA---------TPAAYSG--SPKISSSPNLTSPATKAWTIT--DT 1389

Query: 1607 TLDVTPVIYAGATSKNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTLPFVKTVPTTIMAG 1666
            T   T + Y     K    SS F T+   AP    P + + PT PT+       T+ + G
Sbjct: 1390 TEHSTQLHYTKLAEK----SSGFETQ--SAPG---PVSVVIPTSPTIGSSTLELTSDVPG 1440

Query: 1667 ---IVTPFVGTTAFSPLSSKSTGAIS-------------SIPKTTFS--PFLSATQQSSQ 1708
               ++ P   TT   P+++  + +++             S P +TF+  P +S       
Sbjct: 1441 EPLVLAPSEQTTITLPMATWLSTSLTEEMASTDLDISSPSSPMSTFAIFPPMSTPSHELS 1500

Query: 1709 ADEATTLGILSGITNRSLSTVNSGTGV-ALTDTYSRITVPENMLSPTHADSLHTSFNIQV 1767
              EA T    S I N   +T++   G+ +L  T    TVP                   +
Sbjct: 1501 KSEADT----SAIRNTDSTTLDQHLGIRSLGRTGDLTTVP-------------------I 1537

Query: 1768 SPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLLEKTSLTNYATSLNTPVSYPP-WTPS 1826
            +P  T++ S    +   + T +   S T    SL ++TS+   A+  +    YP   T  
Sbjct: 1538 TPLTTTWTSVIEHSTQAQDTLSATMSPTHVTQSLKDQTSIPASASPSHLTEVYPELGTQG 1597

Query: 1827 SATLPSLTSFVYSPHSTEAEISTPKTSPPPTSQMVEFPVLGTRMTSSNTQPLLMTSWNIP 1886
             ++  + T +  S  +   EI T  T+   T      P +    T S++  + +   ++P
Sbjct: 1598 RSSSEATTFWKPSTDTLSREIETGPTNIQST------PPMDNTTTGSSSSGVTLGIAHLP 1651

Query: 1887 TAEGSQFPISTTINVPTSNEMETETLHLVPGPLSTFTASQTG-LVSKDVMAMSSIPMSGI 1945
               G+  P  T+ N+       T T+ +  G +     S  G  +S+ +  +SS+     
Sbjct: 1652 I--GTSSPAETSTNMALERRSSTATVSMA-GTMGLLVTSAPGRSISQSLGRVSSVLSEST 1708

Query: 1946 ---LPNHGLSENPSLST-SLRAITSTLADVKHTFEKMTTSV--TPGTTLPSILSGATSGS 1999
               + +     +P L+T    A++S+L        +M+TS+  T   T P +      GS
Sbjct: 1709 TEGVTDSSKGSSPRLNTQGNTALSSSLEPSYAEGSQMSTSIPLTSSPTTPDV--EFIGGS 1766

Query: 2000 VISKSPILTWLLSSLPSGSPPATVSNAPHVMTS--STVEVSKSTFLTS--DMISAHPFTN 2055
                  + T + S +   S     S+A  + T+  ST    K    T+  D+ S  P   
Sbjct: 1767 TFWTKEVTTVMTSDISKSSARTESSSATLMSTALGSTENTGKEKLRTASMDLPSPTPSME 1826

Query: 2056 LTTLPSATMSTILTRTIPTPTLGGITTGFPTSLPMSINVTDDIVYISTHPEASSRTTITA 2115
            +T   S T+S     T       G+ T    +L    ++   +   S     S  ++ + 
Sbjct: 1827 VTPWISLTLSNAPNTTDSLDLSHGVHTSSAGTLATDRSLNTGVTRASRLENGSDTSSKSL 1886

Query: 2116 NPRTVSHPSSFSRKTMSPSTTDHTLSVGAMPLPSSTITSS-WNRIPTASSPSTLIIPKPT 2174
            +    +H S    +    S++ H     + P   +T+TS+  NR  + + P + I  +  
Sbjct: 1887 SMGNSTHTSMTYTEKSEVSSSIHPRPETSAPGAETTLTSTPGNRAISLTLPFSSIPVEEV 1946

Query: 2175 LDSLLNIMTTTSTVPGASFPLISTGVTYPFTATVSS------PISSFFETTWLDSTPSFL 2228
            + + +      ++ P    P+    + +  T T+         +SS   +    STP   
Sbjct: 1947 ISTGITSGPDINSAPMTHSPITPPTIVWTSTGTIEQSTQPLHAVSSEKVSVQTQSTPYVN 2006

Query: 2229 STEASTSPTATKSTVSFYNVEMSFS 2253
            S   S SPT   S  S  +    +S
Sbjct: 2007 SVAVSASPTHENSVSSGSSTSSPYS 2031



 Score = 77.8 bits (190), Expect = 2e-13
 Identities = 134/578 (23%), Positives = 225/578 (38%), Gaps = 83/578 (14%)

Query: 218   IIPTVDRTLRCFVPENMTIQEKSTTVSQQIDMTTPSQITGVKPQNTAHSSTLLSQSIPIF 277
             I P +   +   VP + T  + STT     +     + T     + A +ST +S +IP F
Sbjct: 11538 ISPDMSDLVTSLVPSSGT--DTSTTFPTLSETPYEPETTATWLTHPAETSTTVSGTIPNF 11595

Query: 278   ATDYTTISYSNTTSPPLETMTA--QKILKTLVDETATFAVDVLSTSSAISLPTQSISIDN 335
             +   +  + S  TSP ++T +      +   +    T  V   +T ++ ++PT + S   
Sbjct: 11596 SHRGSDTAPSMVTSPGVDTRSGVPTTTIPPSIPGVVTSQVTSSATDTSTAIPTLTPSPGE 11655

Query: 336   TTNSMKKTKSPSSES-------TKTTKMVEAMATEIFQPPTPSNFLS--TSRFTKNS--- 383
                +      P +++       T  +   + MA+ +  PP  S  +S  TS F+ +S   
Sbjct: 11656 PETTASSATHPGTQTGFTVPIRTVPSSEPDTMASWVTHPPQTSTPVSRTTSSFSHSSPDA 11715

Query: 384   --VVSTTSAIKSQSAVTKTTSLFSTIESTSMSTTPCLKQKSTNTGALPISTAGQEFIEST 441
               V++T+   ++ SAV  T S      +  M T+      +  +  +P  T      E+T
Sbjct: 11716 TPVMATSPRTEASSAVLTTIS----PGAPEMVTSQITSSGAATSTTVPTLTHSPGMPETT 11771

Query: 442   A-AGTVPWFTVEKTSPASTHVGTASSFPPEPVLISTAAPVDSVFPRNQTAFPLATTDMKI 500
             A   T P     KT PAST       FP     +S      ++ P  +T+  L T     
Sbjct: 11772 ALLSTHPRTETSKTFPAST------VFPQ----VSETTASLTIRPGAETSTALPTQTTSS 11821

Query: 501   AFTVHSLTLPTRLIETTPA---------------PRTAETELTSTNFQDVSLPRVEDAMS 545
              FT+  L   T  ++ +P                P T  + +  T+   + L      ++
Sbjct: 11822 LFTL--LVTGTSRVDLSPTASPGVSAKTAPLSTHPGTETSTMIPTSTLSLGLLETTGLLA 11879

Query: 546   TSMSKETSSKTFSFLTSFSFTGTESVQTVIDAEATRTALTPEITLAST-VAETMLSSTIT 604
             TS S ETS+ T +   S + +G  S     D   T T+   E + + T V     S T+T
Sbjct: 11880 TSSSAETSTSTLTLTVSPAVSGLSSASITTDKPQTVTSWNTETSPSVTSVGPPEFSRTVT 11939

Query: 605   GRVYT-----QNTPTADGH---------LLTLM--STRSASTSKAPESGPTSTTDE--AA 646
             G   T       TP    H         L T M  +T  A+T  +P    T+TT    A 
Sbjct: 11940 GTTMTLIPSEMPTPPKTSHGEGVSPTTILRTTMVEATNLATTGSSPTVAKTTTTFNTLAG 11999

Query: 647   HLFSSNETIWTSRPDQALLASMNTTTILTFVPNENFTSAFHENTTYTEYLSATTNITPLK 706
              LF+   T     P  + LAS + T+  ++    N  S     ++Y          TP+ 
Sbjct: 12000 SLFTPLTT-----PGMSTLASESVTSRTSY----NHRSWISTTSSYNRRYWTPATSTPVT 12050

Query: 707   AS-PEGKGTTANDATTARYTTAVSKLTSPWFANFSIVS 743
             ++   G  T++  ++TA    A      P+  NF+I +
Sbjct: 12051 STFSPGISTSSIPSSTA----ATVPFMVPFTLNFTITN 12084


>gi|6912464 latrophilin 2 precursor [Homo sapiens]
          Length = 1403

 Score =  210 bits (535), Expect = 2e-53
 Identities = 144/462 (31%), Positives = 229/462 (49%), Gaps = 38/462 (8%)

Query: 2636 FKTKNVTKALTTYVVSASISDDMFIQNLADPVVITLQHIGGNQNYGQVHCAFWDFENNNG 2695
            F  +N T A+ ++V+S SI+ +     L DPV+ TL HI  + NY   +C+FW++     
Sbjct: 727  FIGRNSTIAVNSHVISVSINKESSRVYLTDPVLFTLPHIDPD-NYFNANCSFWNYSERTM 785

Query: 2696 LGGWNSSGCKVKETNVNYTICQCDHLTHFGVLM-DLSRSTVDSVNEQILALITYTGCGIS 2754
            +G W++ GCK+ +TN   T C C HLT+F +LM     +  D V+E +L +IT+ G  IS
Sbjct: 786  MGYWSTQGCKLVDTNKTRTTCACSHLTNFAILMAHREIAYKDGVHELLLTVITWVGIVIS 845

Query: 2755 SIFLGVAVVTYIAFHKLRKDYPAKILINLCTALLMLNLVFLINSWLSSFQKVGVCITAAV 2814
             + L + + T+  F  L+ D    I  NLC  L +   +FLI   +   +    C   A 
Sbjct: 846  LVCLAICIFTFCFFRGLQSDRNT-IHKNLCINLFIAEFIFLIG--IDKTKYAIACPIFAG 902

Query: 2815 ALHYFLLVSFTWMGLEAVHMYLALVKVFNIYIPNYILK--FCLVGWGIPAIMVAITVSVK 2872
             LH+F L +F WM LE V +YL LV+VF      Y  K  + + G+  PA +V ++ ++ 
Sbjct: 903  LLHFFFLAAFAWMCLEGVQLYLMLVEVFE---SEYSRKKYYYVAGYLFPATVVGVSAAID 959

Query: 2873 KDLYGTLSPTTPFCWIKDDSIFYISVVAYFCLIFLMNLSM----FCTVLVQLNSVKSQIQ 2928
               YG    T   CW+  D+ F  S +     I L+N+       C ++   N++K    
Sbjct: 960  YKSYG----TEKACWLHVDNYFIWSFIGPVTFIILLNIIFLVITLCKMVKHSNTLKP--D 1013

Query: 2929 KTRRKMILHDLKGTMSLTFLLGLTWGFAFFAWGPMRNFFLYLFAIFNTLQGFFIFVFHCV 2988
             +R + I   + G  +L  LLGLTW F             YLF IFN  QG FIF+FHC 
Sbjct: 1014 SSRLENIKSWVLGAFALLCLLGLTWSFGLLFINEETIVMAYLFTIFNAFQGVFIFIFHCA 1073

Query: 2989 MKESVREQW----QIHLCCGWLRLD--NSSDGSSRCQIKVGYK-----------QEGLKK 3031
            +++ VR+++    +   CCG L  +  +SS  +S  +    Y             + ++K
Sbjct: 1074 LQKKVRKEYGKCFRHSYCCGGLPTESPHSSVKASTTRTSARYSSGTQSRIRRMWNDTVRK 1133

Query: 3032 IFEHKLLTPSLKSTATSSTFKSLGSAQGTPSEISFP-NDDFD 3072
              E   ++  + ST+T +   SL +A+ T +  + P N +F+
Sbjct: 1134 QSESSFISGDINSTSTLNQGHSLNNARDTSAMDTLPLNGNFN 1175


>gi|163792198 latrophilin 3 precursor [Homo sapiens]
          Length = 1469

 Score =  204 bits (520), Expect = 8e-52
 Identities = 128/393 (32%), Positives = 206/393 (52%), Gaps = 29/393 (7%)

Query: 2641 VTKALTTYVVSASISDDMFIQNLADPVVITLQHIGGNQNYGQVHCAFWDFENNNGLGGWN 2700
            V   + T  ++   S+ ++   LADPVV T++HI  ++     +C+FW +      G W+
Sbjct: 777  VNSPVITAAINKEFSNKVY---LADPVVFTVKHIKQSEENFNPNCSFWSYSKRTMTGYWS 833

Query: 2701 SSGCKVKETNVNYTICQCDHLTHFGVLM-DLSRSTVDSVNEQILALITYTGCGISSIFLG 2759
            + GC++  TN  +T C C+HLT+F VLM  +     D+V++ +L +IT+ G  +S + L 
Sbjct: 834  TQGCRLLTTNKTHTTCSCNHLTNFAVLMAHVEVKHSDAVHDLLLDVITWVGILLSLVCLL 893

Query: 2760 VAVVTYIAFHKLRKDYPAKILINLCTALLMLNLVFLINSWLSSFQKVGVCITAAVALHYF 2819
            + + T+  F  L+ D    I  NLC +L +  L+FLI   ++   +   C   A  LH+F
Sbjct: 894  ICIFTFCFFRGLQSDRNT-IHKNLCISLFVAELLFLIG--INRTDQPIACAVFAALLHFF 950

Query: 2820 LLVSFTWMGLEAVHMYLALVKVFNIYIPNYILKFCLVGWGIPAIMVAITVSVKKDLYGTL 2879
             L +FTWM LE V +Y+ LV+VF     +    F LVG+G+PA++VA++ +V    YG  
Sbjct: 951  FLAAFTWMFLEGVQLYIMLVEVFESE-HSRRKYFYLVGYGMPALIVAVSAAVDYRSYG-- 1007

Query: 2880 SPTTPFCWIKDDSIFYISVVAYFCLIFLMNLSMFCTVLVQL-----------NSVKSQIQ 2928
              T   CW++ D+ F  S +    LI ++N+      L ++             + +   
Sbjct: 1008 --TDKVCWLRLDTYFIWSFIGPATLIIMLNVIFLGIALYKMFHHTAILKPESGCLDNINY 1065

Query: 2929 KTRRKMILHDLKGTMSLTFLLGLTWGFAFFAWGPMRNFFLYLFAIFNTLQGFFIFVFHCV 2988
            +  R  I   + G ++L  LLGLTW F             YLF IFN+LQG FIF+FHCV
Sbjct: 1066 EDNRPFIKSWVIGAIALLCLLGLTWAFGLMYINESTVIMAYLFTIFNSLQGMFIFIFHCV 1125

Query: 2989 MKESVREQW----QIHLCCGWLRLDNSSDGSSR 3017
            +++ VR+++    + H C G  +   SS GS +
Sbjct: 1126 LQKKVRKEYGKCLRTHCCSG--KSTESSIGSGK 1156


>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1542

 Score =  203 bits (516), Expect = 2e-51
 Identities = 359/1569 (22%), Positives = 601/1569 (38%), Gaps = 174/1569 (11%)

Query: 310  TATFAVDVLSTSSAISLPTQSISIDNTTNSMKKTKSPSS----ESTKTTKMVEAMATEIF 365
            T+T    V++ SS  S  T + +  + T +   T S ++    ++++TT    + A    
Sbjct: 9    TSTADSKVITASSMSSETTVAPAAGSNTTTASTTGSETTTILIKASETT--TASTAGSET 66

Query: 366  QPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFSTIESTSMSTTPCLKQKSTNT 425
              P+P+   +T      S ++TTS   S++         +T+ S    TT      S +T
Sbjct: 67   TTPSPTGSQTTIVSISGSEITTTSTAGSEN---------TTVSSAGSGTTTASMAGSEST 117

Query: 426  GALPISTAGQEFIESTAAGTVPWFTVEKTSPASTHVGTASSFPPEPVLISTAAPVDSVFP 485
                ISTAG E    +  GT         S  +T+  T+S         S    V +V  
Sbjct: 118  ----ISTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGS 173

Query: 486  RNQTAFPLATTDMKIAFTVHSLTLPTRLIETTPAPRTAETELTSTNFQDVSLPRVEDAMS 545
               TA+   +     + T   +T        T  P TA +E T+ +        V    +
Sbjct: 174  ETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVS---T 230

Query: 546  TSMSKETSSKTFSFLTSFSFTGTESVQ-TVIDAEATRTALTPEITLASTV-AETMLSSTI 603
            T     T+S   S  T+ S  G+E+ + +   +E T +    E T AST  +ET  + T 
Sbjct: 231  TGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTE 290

Query: 604  TGRVYTQNT-------PTADGHLLTLMSTRSASTSKAPESGPTSTTDEAAHLFSSNETIW 656
              +  T +T        +  G   T+ ST  + T+ A   GP +T    A   SS  T  
Sbjct: 291  DSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTA---SSEVTTV 347

Query: 657  TSRPDQALLASM--NTTTILTFVPNENFTSAFHENTTYTEYLSATTNITPLKASPEGKGT 714
             +   + + AS   + TT ++   +E  T++   + T T+   +TT      AS EG  T
Sbjct: 348  FAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTD---STTGSETTTASTEGSET 404

Query: 715  TANDATTARYTTAVSKLTSPWFANFSIVSGTTSITNMPEFKLTTLLLKTIPMSTKPANEL 774
            T      +  TT             S     T+  ++ + + TT   +   M+       
Sbjct: 405  TTASTEGSEATTV------------STTGSETTTVSITDSETTTTCTEGSEMTAVSTTVF 452

Query: 775  PLTPRETVVPSVDIISTLACIQPNFSTEESASETTQTEINGAIVFGGTTTPVPKSATTQR 834
              T   T    + I ST        STE S + T  T         G+ T    +  ++ 
Sbjct: 453  ETTTASTEGSEITIASTSDSETTTASTEGSETTTVTT--------AGSETKTAYTTGSET 504

Query: 835  LNATVTRKEATSHYLMRKSTIAAVAEVSPF-------STMLEVTDESAQRVTASVTVSSF 887
              A+ T  E T+ + +   T  A  E S         S M  V+ E ++  T S T S  
Sbjct: 505  TTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSET 564

Query: 888  PDIEKLSTPLDNKTATTEVRESWLLTKLVKTTPRSSYNEMTEMFNFNHTYVAHWTSETSE 947
              +   +T L+  T +TE  E       V TT   +  + TE      T  +   SET+ 
Sbjct: 565  TTVS--TTGLETTTTSTEGSE----MTTVSTTGAETTTDSTE--GSGTTAASTAGSETTT 616

Query: 948  GISAGSPTSGSTHIFGEPLGASTTRISETSFSTTPTDRTATSLSDGILPPQPTAAHSSAT 1007
              +A S  + ++    E   ASTT  SET+ ++T +  T T+ ++G          S  T
Sbjct: 617  VSTADSENTTASTADSETTSASTTG-SETTTASTTSSETTTASTEG----------SETT 665

Query: 1008 PVPVTHMFSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVPPL 1067
             V  T               ++E TM   +   R  +++  S+ + +S+T   T +    
Sbjct: 666  TVSTT---------------DSETTMVSTTGSERTITSTEGSETTTVSATGSETTV--ST 708

Query: 1068 DQTASTTIVIVPTHGDLIRTT-SEATVISVRKTSMAVPSLTETPFHSLRLSTPVTAKAET 1126
            + + +TT+ I  +    + TT SE T  S   + +   S+T +       +T  T  +ET
Sbjct: 709  EGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGS-----ETTTASTEGSET 763

Query: 1127 TLFSTSVDTVTPSTHTLVCSKPPPDNIPPASSTHVISTTSTPEATQPISQVEETSTYALS 1186
            T  ST   + T S  T              ++   I  + T  A+   S+  + ST +  
Sbjct: 764  TTASTE-GSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSK 822

Query: 1187 FPYTFSGGGVVASLATGTTETSVV----DETTPSHISANKLTTSVNSHISSSATYRVH-- 1240
                F+        +T  +ET+ V     ET P+  + ++ TT+ ++  S + T      
Sbjct: 823  MTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGS 882

Query: 1241 --TPVSIQLVTSTSVLSSDKDQMTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTD 1298
              T  S +   +T+  +   +  T S   +  T   TE S +     + + G+    ++ 
Sbjct: 883  ETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTT---ASTEGSEITTVST 939

Query: 1299 TGFPETTKISSHQTHSPSEIPLGTPSDGNLASSPTSGSTQITPT-----LTSSNTVGVHI 1353
            TG  ETT  S+      SE    +     L +  T+GS  IT +      T+  T+G   
Sbjct: 940  TG-SETTTAST----EGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSET 994

Query: 1354 PEMSTSLGKTALPSQALTITTFLCPEKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDT 1413
               ST+  +T   S A + TT    E   T+ + +    T  +    T  T + + G +T
Sbjct: 995  TTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSET 1054

Query: 1414 SFVDTTTSSSTRISNPMDINTTFSHLHSLRTQPEVTSVASFISESTQTFPESLSLSTAGL 1473
            + V T  S +T +       TT S   S     E T+V++  SE+T      L  +T   
Sbjct: 1055 TTVTTAGSETTAVYTTGSETTTTSTEGS-----ETTTVSTTGSETTTASTADLETTTVST 1109

Query: 1474 YNDGFTVLS---DRITTAFSVPNVPTMLPRESSMATSTPIYQMSSLPVNVTAFTSKKVSD 1530
               G T  S      TT +   +  T    E S AT+      ++     TA T+     
Sbjct: 1110 SGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTV----STTSSETTTASTTGSEMT 1165

Query: 1531 TPPIVITKSSKTMHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPA-TVSSDTSTRVGLFS 1589
            T   V T  S+T     + S  T +S   SE ++     S  T A T  S+T+T     S
Sbjct: 1166 T---VFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTA----S 1218

Query: 1590 TLLSSVTPRTTMTMQTSTLDVTPVIYAGATSKNKMVSSAFTTEMIEAPSRITPTTFLSPT 1649
            T  S  T  +T   +T+T   T    +  +S     ++AF   +I + + I  T  L PT
Sbjct: 1219 TAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAF---IIGSETTIASTASLEPT 1275

Query: 1650 EPTLPFVKTVPTTIMAGIVTPFVGTTAFSPLSSKSTGAISSIPKTTFSPFLSATQQSSQA 1709
              +L   +T   +I A       G TA S   S +T  ++     +  P  +     ++ 
Sbjct: 1276 ATSLTGSETTTVSITAS------GATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRT 1329

Query: 1710 DEATTLGILSGITNRSLSTVNSGTGVALTDTYSRITVPENMLSPTHADSLHTSFNIQVSP 1769
                     +G    + S+V    G+  T + +  TVP  +L   +   L TS     + 
Sbjct: 1330 ---------TGTRLTASSSVTMAPGMDFTASAASHTVPGIVL---NTSGLGTS--TMGAS 1375

Query: 1770 SLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLLEKTSLTNYATSLNTPVSY-PPWTPSSA 1828
            S TS       T + +  T+     T  ++      S+++  T++  P  Y  PW     
Sbjct: 1376 STTSAHGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNVIKPSGYLQPWAIILI 1435

Query: 1829 TLPSLTSFV 1837
            +L ++ + V
Sbjct: 1436 SLAAVVAAV 1444



 Score =  194 bits (493), Expect = 1e-48
 Identities = 340/1430 (23%), Positives = 567/1430 (39%), Gaps = 181/1430 (12%)

Query: 235  TIQEKSTTVSQQIDMTTPSQITGVKPQ-NTAHSSTLLSQSIPIFATDYTTIS-YSNTTSP 292
            T   ++TTVS     TT + + G +   +TA S T    ++ I  T+ T +S   + T+ 
Sbjct: 91   TAGSENTTVSSAGSGTTTASMAGSESTISTAGSETT---TVSITGTETTMVSAMGSETTT 147

Query: 293  PLETMTAQKILKTLVDETATFAVDVLSTSSAISLPTQSISIDNTTNSM-------KKTKS 345
               T +   +  T   ET T +     T++A +  +++ +   T + M        +T +
Sbjct: 148  NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETIT 207

Query: 346  PSSESTKTTKMVEAMATEIFQPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFS 405
            PS+  ++TT +  A +       T S   +T+  T +S  +  S + S++    T    +
Sbjct: 208  PSTAGSETTTVSTAGSETTTVSTTGSE--TTTASTAHSETTAASTMGSETTKVSTAGSET 265

Query: 406  TIESTSMSTTPCLKQKS-TNTGALPIS---TAGQEFIESTAAGTVPWFTVEKTSPAST-- 459
            T+ +    TT    + S TNT     S   TA     E+TAA T    T  + + AST  
Sbjct: 266  TVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST----TGSEPTMASTMG 321

Query: 460  -HVGTASSFPPEPVLISTAAP-VDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETT 517
                 AS+  PE   +STA+  V +VF         +T   +      + T+ T   ETT
Sbjct: 322  SETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSE------TTTVSTTGSETT 375

Query: 518  PAP-RTAETELTSTNFQDVSLPRVEDAMSTSMSKETSSKTFSFLTSFSFTGTESVQTVID 576
             A    +ET   ST   + +    E + +T+ S E S  T     + S TG+E+    I 
Sbjct: 376  TASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEAT-----TVSTTGSETTTVSIT 430

Query: 577  AEATRTALTP--EITLASTVAETMLSSTITGRVYTQNTPTADGHLLTLMSTRSASTSKAP 634
               T T  T   E+T  ST             V+   T + +G  +T+ ST  + T+ A 
Sbjct: 431  DSETTTTCTEGSEMTAVSTT------------VFETTTASTEGSEITIASTSDSETTTAS 478

Query: 635  ESGPTSTTDEAAHLFSSNETIWT--SRPDQALLASMNTTTILTFVPNENFTSAFHENTTY 692
              G  +TT   A   S  +T +T  S    A    + TTT+ T     + T+A  E +  
Sbjct: 479  TEGSETTTVTTAG--SETKTAYTTGSETTTASNTGLETTTVFTI--GSDTTTASTEGSET 534

Query: 693  TEYLSATTNITPLKASPEGK-----GTTANDATTARYTTAVSKLTSPWFANFSIVS--GT 745
            T   +  + +T +  S EG       TT ++ TT   T   +  TS   +  + VS  G 
Sbjct: 535  TAVSATGSEMTTV--STEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGA 592

Query: 746  TSITNMPEFKLTTLL----LKTIPMSTKPANELPLTPRETVVPSVDIISTLACIQPNFST 801
             + T+  E   TT       +T  +ST  +         T   + D  +T A       +
Sbjct: 593  ETTTDSTEGSGTTAASTAGSETTTVSTADS-------ENTTASTADSETTSA---STTGS 642

Query: 802  EESASETTQTEINGAIVFGGTTTPVPKS-ATTQRLNATVTRKEATSHYLMRKSTIAAVAE 860
            E + + TT +E   A   G  TT V  + + T  ++ T + +  TS      +T++A   
Sbjct: 643  ETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGS 702

Query: 861  VSPFSTMLEVTDESAQRVTASVTVSSFPDIEKLSTPLDNKTATTEVRESWLLTKLV---K 917
             +  ST      E +   T S+T S   +  K+ST   ++T TT    S + T  +   +
Sbjct: 703  ETTVST------EGSGTTTVSITGS---ETTKVST-TGSETTTTSTEGSEITTASITGSE 752

Query: 918  TTPRSSYNEMTEMFNFNHTYVAHWTSETSEGISAGSPTS--------GSTHIFGEPLGAS 969
            TT  S+    T   +   +     ++  SE  +A + +S        GS       +G+ 
Sbjct: 753  TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSE 812

Query: 970  TTRISETS--FSTTPTDRTATSLSDGILPPQPTAAHSSATPVPVTHMFSLPVNGSSVVAE 1027
            TT++S  S   +T  T+ + T+++        T + + +  +P +   S     +S    
Sbjct: 813  TTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGS 872

Query: 1028 ETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVPPLDQTASTTIVIVPTHGDLIRT 1087
            ET    +E S    A + S  +  +    +  TTA     + T ++T             
Sbjct: 873  ETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTST------------E 920

Query: 1088 TSEATVISVRKTSMAVPSLT--ETPFHSLRLSTPVTAKAE----TTLFSTSVDTVTPS-- 1139
             SE T  S   + +   S T  ET   S   S   TA  E    TT+ +T  +T+T S  
Sbjct: 921  GSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAE 980

Query: 1140 -THTLVCSKPPPDNIPPASSTHVISTTSTPEATQPISQVEETSTYALSFPYTFSGGGVVA 1198
             + T   +    +    +++    +T ST  +    + +E + T  +S   T S    V+
Sbjct: 981  GSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVS--STGSETTTVS 1038

Query: 1199 SLATGTTETSVVDETTPSHISANKLTTSVNSHISSSATYRVH----TPVSIQLVTSTSVL 1254
            +  T TT TS     T +  +A   TT+V +  S + T        T VS     +T+  
Sbjct: 1039 TTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAS 1098

Query: 1255 SSDKDQMTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHS 1314
            ++D +  T+S   +  T   T  S +   +I+ S+ T +     T   E T +S+     
Sbjct: 1099 TADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTA----STEGSEATTVST----- 1149

Query: 1315 PSEIPLGTPSDGNLASSPTSGSTQITPTLTSSNTVGVHIPEMSTSLGKTALPSQALTITT 1374
                   T S+   AS+  S  T +  T++ + TV     E +TS   +A  S+A T +T
Sbjct: 1150 -------TSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTS---SAAGSEATTTST 1199

Query: 1375 FLCPEKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINT 1434
                  E+T+A  A +  T      S   T S S  +  +   T + +ST  S   + NT
Sbjct: 1200 ---EGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNT 1256

Query: 1435 TFSHLHSLRTQPEVTSVASFISESTQTFPESLSLSTAGLYNDGFTVLSDRITTAFSVPNV 1494
             F     + ++  + S AS   E T T       +T  +   G T  S   TT  S   V
Sbjct: 1257 AF----IIGSETTIASTASL--EPTATSLTGSETTTVSITASGATAAS---TTVSSTTFV 1307

Query: 1495 PTMLPRESSMATSTPIYQMSSLPVNVTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTA 1554
             T        AT   I  +++ P++ T  T  +++         SS TM PG        
Sbjct: 1308 LT-------KATDVSIQPITNTPMSGTRTTGTRLT-------ASSSVTMAPGM----DFT 1349

Query: 1555 TSGPMSEMSSIPVNNSAFTPATVSSDTSTRVGLFSTLLSSVTPRTTMTMQ 1604
             S     +  I +N S    +T+ + ++T      T   S    T+ T Q
Sbjct: 1350 ASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPTSSTFQ 1399



 Score =  192 bits (489), Expect = 3e-48
 Identities = 350/1558 (22%), Positives = 595/1558 (38%), Gaps = 186/1558 (11%)

Query: 240  STTVSQQIDMTTPSQITGVKP---QNTAHSSTLLSQSIPIF--ATDYTTISYSNT-TSPP 293
            ST  S+ I  ++ S  T V P    NT  +ST  S++  I   A++ TT S + + T+ P
Sbjct: 10   STADSKVITASSMSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTP 69

Query: 294  LETMTAQKILKTLVDETATFAVDVLSTSSAISLPTQSISIDNTTNSMKKTKSPSSESTKT 353
              T +   I+     E  T      ST+ + +    S     TT SM  ++S  S +   
Sbjct: 70   SPTGSQTTIVSISGSEITT-----TSTAGSENTTVSSAGSGTTTASMAGSESTISTAGSE 124

Query: 354  TKMVEAMATEIFQPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFSTIESTSMS 413
            T  V    TE     T       S  T NS  S+ + + S +    TT      E+T+  
Sbjct: 125  TTTVSITGTE-----TTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAY 179

Query: 414  TTPCLKQKSTNTGA--LPISTAGQEFIESTAAGTVPWFTVEKTSPASTHVGTASSFPPEP 471
            T       ++ TG+    + TAG E I  + AG+         S A +   T S+   E 
Sbjct: 180  TADSETTAASTTGSEMTTVFTAGSETITPSTAGS----ETTTVSTAGSETTTVSTTGSET 235

Query: 472  VLISTAAPVDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETTPAPRTAETELTSTN 531
               STA            A  + +   K++      T+ T   ETT     A TE + TN
Sbjct: 236  TTASTA------HSETTAASTMGSETTKVSTAGSETTVSTAGSETT----AASTEDSETN 285

Query: 532  FQDVSLPRVEDAMSTSMSKETSSKTFSFLTSFSFTGTE-SVQTVIDAEATR--TALTPEI 588
                   +   A +T      +S T S  T  S  G+E ++ + I  E T+  TA +   
Sbjct: 286  TAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVT 345

Query: 589  TLASTVAETMLSSTITGRVYTQNTPTADGHLLTLMSTRSASTSKAPESGPTSTTDEAAHL 648
            T+ +  +ET+ +ST+     T +T  ++    ++M + +++ S       T++T+ +   
Sbjct: 346  TVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETT 405

Query: 649  FSSNE-----TIWTSRPDQALLASMNTTTILTFVPNENFTSAFHENTTYTEYLSATTNIT 703
             +S E     T+ T+  +   ++  ++ T  T       T+    +TT  E  +A+T  +
Sbjct: 406  TASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAV---STTVFETTTASTEGS 462

Query: 704  PLKASPEGKGTTANDATTARYTTAVSKLTSPWFANFSIVSGTTSITNMPEFKLTTLLLKT 763
             +  +      T   +T    TT V+   S     ++  S TT+ +N     L T  + T
Sbjct: 463  EITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNT---GLETTTVFT 519

Query: 764  IPMSTKPANELPLTPRETVVPSVDIISTLACIQPNFSTEESASETTQTEINGAIVFGGTT 823
            I   T  A+              ++ +       N +   + SETT     G      TT
Sbjct: 520  IGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG---LETTT 576

Query: 824  TPVPKSATTQRLNATVTRKEATSHYLMRKSTIAAVAEVSPFSTMLEVTDESAQRVTA-SV 882
            T    S  T     + T  E T+       T AA    S  +T+     E+    TA S 
Sbjct: 577  TSTEGSEMT---TVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE 633

Query: 883  TVSSFPDIEKLSTPLDNKTATTEVRESWLLTKLVKTTPRSSYNEMTEMFNFNHTYVAHWT 942
            T S+     + +T     + TT        T  V TT   S   M        T  +   
Sbjct: 634  TTSASTTGSETTTASTTSSETTTASTEGSETTTVSTT--DSETTMVSTTGSERTITSTEG 691

Query: 943  SETSEGISAGSPTSGSTHIFGEPLGASTTRISETSFSTTPTDRTATSLSDGILPPQPTAA 1002
            SET+   + GS T+ ST       G+ TT +S T   TT    T +         + T  
Sbjct: 692  SETTTVSATGSETTVSTE------GSGTTTVSITGSETTKVSTTGS---------ETTTT 736

Query: 1003 HSSATPVPVTHMFSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTA 1062
             +  + +    +       +S    ET    +E S    A +T   +  ++ +S+  T A
Sbjct: 737  STEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMA 796

Query: 1063 LVPPLDQTASTTIVIVPTHGDLIRTTSEATVISVRKTSMAVPSLTETPFHSLRLSTPVTA 1122
             +   + T ++TI             SE T +S                 S +++T  T 
Sbjct: 797  SIMGSETTMASTI------------GSETTKVSTA---------------SSKMTTVFTE 829

Query: 1123 KAETTLFSTSVDTVTPSTHTLVCSKPPPDNIPPA---SSTHVISTTSTPEATQPISQVEE 1179
             +ETT+ ST+      ++ T   S    + IP +   S T   ++T   E T   ++  E
Sbjct: 830  NSETTIASTT------ASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE 883

Query: 1180 TSTYALSFPYTFSGGGVVASLATGTTETSVVDETTPSHISANKLTT--SVNSHISSSATY 1237
            T+T +     T +   + +   T +TE S   ETT +    ++ TT  +  S I++ +T 
Sbjct: 884  TTTASTESSETTTATTIGSETTTASTEGS---ETTTTSTEGSETTTASTEGSEITTVSTT 940

Query: 1238 RVHTPVSIQLVTSTSVLSSDKDQMTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMT 1297
               T  +    + T+  S++  ++T        T+  T              G+ ++ ++
Sbjct: 941  GSETTTASTEGSETTTASTEGSELT--------TVSTT--------------GSETITVS 978

Query: 1298 DTGFPETTKISSHQTHSPSEIPLGTPSDGNLASSPTSGSTQITPTLTSSNTVGVHIPEMS 1357
              G  ETT +    T   SE    + +     +  T+GS   T ++  S T  V     S
Sbjct: 979  AEG-SETTTV----TTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTV-----S 1028

Query: 1358 TSLGKTALPSQALTITTFLCPEKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVD 1417
            ++  +T   S   T TT    E   T+ +      T  +    +  T + + G +T+ V 
Sbjct: 1029 STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVS 1088

Query: 1418 TTTSSSTRISNPMDINTTFSHLHSLRTQPEVTSVASFISESTQTF----PESLSLSTAGL 1473
            TT S +T  S   D+ TT     ++ T    T+ AS     T T      ++ + ST G 
Sbjct: 1089 TTGSETTTAST-ADLETT-----TVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGS 1142

Query: 1474 YNDGFTVLSDRITTAFS----VPNVPTMLPRESSMATSTPIYQMSSLPVNVTAFTSKKVS 1529
                 +  S   TTA +    +  V T +   ++++T       SS   +    TS + S
Sbjct: 1143 EATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGS 1202

Query: 1530 DTPPIVITKSSKTMHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPATVSSDTSTR--VGL 1587
            +T       S  T          TA++      ++    +   TP++  S+T+T   +G 
Sbjct: 1203 ETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGS 1262

Query: 1588 FSTLLSSVTPRTTMTMQTSTLDVTPVIYA-GATSKNKMVSSAFTTEMIEAPSRITPTTFL 1646
             +T+ S+ +   T T  T +   T  I A GAT+ +  VSS               TTF+
Sbjct: 1263 ETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSS---------------TTFV 1307

Query: 1647 SPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSPLSS------KSTGAISSIPKTTF--SP 1698
              T+ T   ++ +  T M+G  T     TA S ++        ++ A  ++P      S 
Sbjct: 1308 L-TKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSG 1366

Query: 1699 FLSATQQSSQADEATTLGILSGITNRSLSTVNSGTGVAL--TDTYSRITVPENMLSPT 1754
              ++T  +S    A  +   +G T    S+    TG     T+T S    P N++ P+
Sbjct: 1367 LGTSTMGASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNVIKPS 1424



 Score =  189 bits (480), Expect = 4e-47
 Identities = 349/1512 (23%), Positives = 586/1512 (38%), Gaps = 191/1512 (12%)

Query: 523  AETELTSTNFQDVSLPRVEDAMSTSMSKETSSKTFSFLTSFSFTGTESVQTVIDAEATRT 582
            A +E T+T+  D    +V  A S S     +    S  T+ S TG+E+   +I A  T T
Sbjct: 2    AGSEATTTSTAD---SKVITASSMSSETTVAPAAGSNTTTASTTGSETTTILIKASETTT 58

Query: 583  ALTPEITLASTVAETMLSSTITGRVYTQNTPTADGHLLTLMSTRSASTSKAPESGPTSTT 642
            A T         +ET              TP+  G   T++S   +  +    +G  +TT
Sbjct: 59   ASTAG-------SET-------------TTPSPTGSQTTIVSISGSEITTTSTAGSENTT 98

Query: 643  DEAAHLFSSNETIWTSRPDQALLASMNTTTILTFVPNENFTSAFHENTTYTEYLSATTNI 702
              +A   ++  ++  S    +   S  TT  +T        SA    TT     S+ T +
Sbjct: 99   VSSAGSGTTTASMAGSESTISTAGSETTTVSITGT-ETTMVSAMGSETTTNSTTSSETTV 157

Query: 703  TPLKASPEGKGTTANDATTARYTTAVSKLTSPWFANFSIVSGTTSITNMPEFKLTTLLLK 762
            T    S     +T    TT  Y TA S+ T+             S T      + T   +
Sbjct: 158  TSTAGSETTTVSTVGSETTTAY-TADSETTA------------ASTTGSEMTTVFTAGSE 204

Query: 763  TIPMSTKPANELPLTPRETVVPSVDIISTLACIQPNFSTEESASETTQTEINGAIVFGGT 822
            TI  ST  +     T   T       +ST         +E + + T  +E   A   G  
Sbjct: 205  TITPSTAGSE---TTTVSTAGSETTTVSTT-------GSETTTASTAHSETTAASTMGSE 254

Query: 823  TTPVPKSATTQRLNATVTRKEATSHYLMRKSTIAAVAEVSPFSTMLEVTDESAQRVTASV 882
            TT V             T    T+       T AA  E S  +T      E ++  TAS 
Sbjct: 255  TTKVS------------TAGSETTVSTAGSETTAASTEDSETNTAF---TEDSKTTTAST 299

Query: 883  TVSSFPDIEKLSTPLDNKTATTEVRESWLLTKLVKTTPR--SSYNEMTEMFNFNHTYVAH 940
            T   F      +T  +   A+T   E+ + + +   T +  ++ +E+T +F      +  
Sbjct: 300  T--GFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRA 357

Query: 941  WT--SETSEGISAGSPTSGSTHIFGEPLGASTTRISETSFSTTPTDRTATSLSDGILPPQ 998
             T  SET+   + GS T+ +  I G      +T  SET+ ++T    T T+ ++G     
Sbjct: 358  STVGSETTTVSTTGSETT-TASIMGSETSTDSTTGSETTTASTEGSETTTASTEG----- 411

Query: 999  PTAAHSSATPVPVTHMFSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTT 1058
                 S AT V  T   +  V   S+   ET  T +E S +  A ST+V       ++T 
Sbjct: 412  -----SEATTVSTTGSETTTV---SITDSETTTTCTEGSEMT-AVSTTVFE-----TTTA 457

Query: 1059 MTTALVPPLDQTASTTIVIVPTHGDLIRTTSEATVISVRKTSMAVPSLTETPFHS-LRLS 1117
             T      +  T+ +      T G    TT+  T  S  KT+    S T T  ++ L  +
Sbjct: 458  STEGSEITIASTSDSETTTASTEGS--ETTTVTTAGSETKTAYTTGSETTTASNTGLETT 515

Query: 1118 TPVTAKAETTLFS-----TSVDTVTPSTHTLVCSKPPPDNI--PPASSTHVISTT---ST 1167
            T  T  ++TT  S     T+  + T S  T V ++   +       S T  +STT   +T
Sbjct: 516  TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 575

Query: 1168 PEATQPISQVEETSTYALSFPYTFSGGGVVASLATG--TTETSVVDETTPSHISANKLTT 1225
              +T+       ++T A +   +  G G  A+   G  TT  S  D    +  +A+  TT
Sbjct: 576  TTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETT 635

Query: 1226 SVNS----HISSSATYRVHTPVSIQLVTSTSVLSSDKDQMTISLGKTPRTMEVTEMSPSK 1281
            S ++      ++S T    T  S +   +T+V ++D +   +S   + RT+  TE S + 
Sbjct: 636  SASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 695

Query: 1282 NSFISYSRGTPSLEMTDTGF-----PETTKISSHQTHSP------SEIPLGTPSDGNLAS 1330
                + S  T S E + T        ETTK+S+  + +       SEI   + +     +
Sbjct: 696  TVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTT 755

Query: 1331 SPTSGSTQITPT-----LTSSNTVGVHIPEMSTSLGKTALPSQALTITTFLCPEKESTSA 1385
            + T GS   T +      TS++T G      ST+  +T + S   + TT        T+ 
Sbjct: 756  ASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTK 815

Query: 1386 LPAYTPRTVEMIVNSTYVTHSVSYGQDTSFV---------------DTTTSSSTRISNPM 1430
            +   + +   +   ++  T + +   +T+ V               +TTT++ST  S   
Sbjct: 816  VSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETT 875

Query: 1431 DINTTFSHLHSLRTQPEVTSVASFISESTQTF----PESLSLSTAGLYNDGFTVLSDRIT 1486
              +T  S   +  T+   T+ A+ I   T T      E+ + ST G      +     IT
Sbjct: 876  TASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEIT 935

Query: 1487 TAFSVPNVPTMLPRESSMATSTPIYQMSSLPVNVTAFTSKKVSDTPPIVITKSSKTMHPG 1546
            T  +  +  T    E S  T+          V+ T   +  VS        + S+T    
Sbjct: 936  TVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVS-------AEGSETTTVT 988

Query: 1547 CLKSPCTATSGPMSEMSSIPVNNSAFTPATVSSDTSTRV---GLFSTLLSSVTPRTTMTM 1603
             + S  T  S   SE +++    S  T A++    +T V   G  +T +S+    TT+T 
Sbjct: 989  TMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTIT- 1047

Query: 1604 QTSTLDVTPVIYAGATSKNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTLPFVKTVPTTI 1663
             T   + T V  AG+ +     + + TT      S  T T   + +E T      + TT 
Sbjct: 1048 STEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSE-TTTVSTTGSETTTASTADLETTT 1106

Query: 1664 MAGIVTPFVGTTAFSPLSSKSTGAISSIPKTTFSPFLSATQQSSQADEATTLGILSGITN 1723
            ++   T   GTT  S   S++T    +  KTT +        S++  EATT+   S  T 
Sbjct: 1107 VS---TSGSGTTTASTAGSETTTVYITGSKTTTA--------STEGSEATTVSTTSSETT 1155

Query: 1724 RSLSTVNSGTGV--ALTDTYSRITVPENMLSPTHADSLHTSFNIQVSPSLTSFKSASGPT 1781
             + +T +  T V   +++T +  T+     + + A S  T+ + + S + T+  + S  T
Sbjct: 1156 TASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETT 1215

Query: 1782 KNVKTTTNCFSSNTRKMTSLLEKTSLTNYATSLNTPVSYPPWT------------PSSAT 1829
                T +   S  T   TS  E  +     +  +TP S    T             S+A+
Sbjct: 1216 ----TASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTAS 1271

Query: 1830 L-PSLTSFVYSPHSTEAEISTPKTSPPPTSQMVEFPVLGTRMTSSNTQPLLMTSWNIPTA 1888
            L P+ TS   S  +T +  ++  T+   T     F +  T+ T  + QP+  T  +    
Sbjct: 1272 LEPTATSLTGSETTTVSITASGATAASTTVSSTTFVL--TKATDVSIQPITNTPMSGTRT 1329

Query: 1889 EGSQFPISTTINV-PTSNEMETETLHLVPGPLSTFTASQTGLVSKDVMAMSSIPMSGILP 1947
             G++   S+++ + P  +   +   H VPG       + +GL +  + A S+    G+  
Sbjct: 1330 TGTRLTASSSVTMAPGMDFTASAASHTVPG----IVLNTSGLGTSTMGASSTTSAHGVRT 1385

Query: 1948 NHGLSENPSLST 1959
              G +  P+ ST
Sbjct: 1386 TTGSTREPTSST 1397



 Score =  168 bits (425), Expect = 9e-41
 Identities = 289/1325 (21%), Positives = 519/1325 (39%), Gaps = 167/1325 (12%)

Query: 943  SETSEGISAGSPTSGSTHIFGEPLGASTTRISETSFSTTPTDRTATSLSDGILPPQPTAA 1002
            SE +   +A S    ++ +  E   A     + T+ STT ++ T   +         TA 
Sbjct: 4    SEATTTSTADSKVITASSMSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAG 63

Query: 1003 HSSATPVPVTHMFSL-PVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTT 1061
              + TP P     ++  ++GS +    T    SE +T++ A S +  + ++   ST  T 
Sbjct: 64   SETTTPSPTGSQTTIVSISGSEITT--TSTAGSENTTVSSAGSGTTTASMAGSESTISTA 121

Query: 1062 ALVPPLDQTASTTIVIVPTHGDLIRT----TSEATVISVR----KTSMAVPSLTETPF-- 1111
                       T   +V   G    T    +SE TV S       T   V S T T +  
Sbjct: 122  GSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTA 181

Query: 1112 HSLRLSTPVTAKAETTLFSTSVDTVTPSTHTLVCSKPPPDNIPPASSTHVISTTSTPEAT 1171
             S   +   T    TT+F+   +T+TPST                S T  +STT +   T
Sbjct: 182  DSETTAASTTGSEMTTVFTAGSETITPST----AGSETTTVSTAGSETTTVSTTGSETTT 237

Query: 1172 QPISQVEETSTYALSFPYTFSGGGVVASLATGTTETSVVDETTPSHISANKLTTSV--NS 1229
               +  E T+   +    T      V++  + TT ++   ETT +    ++  T+   +S
Sbjct: 238  ASTAHSETTAASTMGSETT-----KVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDS 292

Query: 1230 HISSSATYRVHTPVSIQLVTSTSVLSSDKDQMTISLGKTPRTMEVTEMSPSKNSFISYSR 1289
              ++++T    T  +    +  ++ S+   + T++    P T +V+  S    +   ++ 
Sbjct: 293  KTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTV--FAA 350

Query: 1290 GTPSLEMTDTGFPETTKISSHQTHSPSEIPLG--TPSDGNLASSPTSGSTQITPTLTSSN 1347
            G+ ++  +  G  ETT +S+  + + +   +G  T +D    S  T+ ST+ + T T+S 
Sbjct: 351  GSETIRASTVG-SETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTAS- 408

Query: 1348 TVGVHIPEMSTSLGKTALPSQALTITTFLCPEKESTSALPAYTPRTVEMIVNSTYVTHSV 1407
            T G     +ST+  +T   S   + TT  C E    +A+      T          T + 
Sbjct: 409  TEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFET----------TTAS 458

Query: 1408 SYGQDTSFVDTTTSSSTRISNPMDINTTFSHLHSLRTQPEVTSVASFISESTQTFPESLS 1467
            + G + +   T+ S +T  S      TT            VT+  S    +  T  E+ +
Sbjct: 459  TEGSEITIASTSDSETTTASTEGSETTT------------VTTAGSETKTAYTTGSETTT 506

Query: 1468 LSTAGLYNDGFTVLSDRITTAFSVPNVPTMLPRESSMATSTPIYQMSSLPVNVTAFTSKK 1527
             S  GL            TT F++ +  T    E S  T+     +S+    +T  +++ 
Sbjct: 507  ASNTGL----------ETTTVFTIGSDTTTASTEGSETTA-----VSATGSEMTTVSTEG 551

Query: 1528 VSDTPPIVITKSSKTMHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPATVSSDTSTRVGL 1587
              +T        + T+    L++  T+T G  SEM+++    +  T  +     +T    
Sbjct: 552  SENTTVSTTGSETTTVSTTGLETTTTSTEG--SEMTTVSTTGAETTTDSTEGSGTTAAST 609

Query: 1588 FSTLLSSVTPRTTMTMQTSTLDVTPVIYAGATSKNKMVSSAFTTEMIEAPSRITPTTFLS 1647
              +  ++V+   +     ST D +    A  T      +S  ++E   A +  + TT +S
Sbjct: 610  AGSETTTVSTADSENTTASTAD-SETTSASTTGSETTTASTTSSETTTASTEGSETTTVS 668

Query: 1648 PTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSPLSSKSTGAISSIPKTTFSPFLSATQQSS 1707
             T+                  T  V TT     S ++  +      TT S   S T  S+
Sbjct: 669  TTDSE----------------TTMVSTTG----SERTITSTEGSETTTVSATGSETTVST 708

Query: 1708 QADEATTLGILSGITNRSLSTVNSGTGVALTD----TYSRITVPENMLSPTHADSLHTSF 1763
            +    TT+ I    T + +ST  S T    T+    T + IT  E   + T      T+ 
Sbjct: 709  EGSGTTTVSITGSETTK-VSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA- 766

Query: 1764 NIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLL-EKTSLTNYATSLNTPVSYPP 1822
                  S    ++ S  T   +TTT   +S+   M S++  +T++ +   S  T VS   
Sbjct: 767  ------STEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVS--- 817

Query: 1823 WTPSSATLPSLTSFVYSPHSTEAEISTPKTSPPPTSQMVEFPVLGTRMTSSNTQPLLMTS 1882
                +A+    T F  +  +T A  +  +T+   T+     P       ++ T     + 
Sbjct: 818  ----TASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSE 873

Query: 1883 WNIPTAEGSQFPISTTINVPTSNEMETETLHLVPGPLSTFTASQTGLVSKDVMAMSSIPM 1942
                + EGS+    TT     S+E  T T        ++   S+T   S +    ++   
Sbjct: 874  TTTASTEGSE----TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAST 929

Query: 1943 SGILPNHGLSENPSLSTSLRAITSTLADVKHTFEKMTTSVTPGTTLPSILSGATSGSVIS 2002
             G       SE  ++ST+    T+   +   T    TT+ T G+ L ++ +  +    +S
Sbjct: 930  EG-------SEITTVSTTGSETTTASTEGSET----TTASTEGSELTTVSTTGSETITVS 978

Query: 2003 KSPILTWLLSSLPS--------GSPPATVSNAPHVMTSSTVEVSKSTFLTSDMISAHPFT 2054
                 T  ++++ S        GS   TVS A    T++++E S++T ++S         
Sbjct: 979  AEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSS--------- 1029

Query: 2055 NLTTLPSATMSTILTRTIPTPTLGGITTGFPTSLPMSINVTDDIVYISTHPEASSRTTIT 2114
              T   + T+ST  T T  T T G  TT   T+       ++     +T  E ++ +T  
Sbjct: 1030 --TGSETTTVSTTGTETTITSTEGSETTTVTTA------GSETTAVYTTGSETTTTSTEG 1081

Query: 2115 ANPRTVSHPSSFSRKTMSPSTTDHTLSVGAMPLPSSTITSSWNRIPTASSPSTLIIPKPT 2174
            +   TVS   S   +T + ST D         L ++T+++S +   TAS+  +    + T
Sbjct: 1082 SETTTVSTTGS---ETTTASTAD---------LETTTVSTSGSGTTTASTAGS----ETT 1125

Query: 2175 LDSLLNIMTTTSTVPGASFPLISTGVTYPFTA-TVSSPISSFFETTWLDSTPSFLSTEAS 2233
               +    TTT++  G+    +ST  +   TA T  S +++ F T    +T S + +EA+
Sbjct: 1126 TVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEAT 1185

Query: 2234 TSPTA 2238
            TS  A
Sbjct: 1186 TSSAA 1190



 Score =  166 bits (419), Expect = 4e-40
 Identities = 329/1465 (22%), Positives = 568/1465 (38%), Gaps = 155/1465 (10%)

Query: 837  ATVTRKEATSHYLMRKSTIAAVAEVSPFSTMLEVTDESAQRVTASVTVSSFPDIEKLSTP 896
            +T   K  T+  +  ++T+A  A  +  +     ++ +   + AS T ++     + +TP
Sbjct: 10   STADSKVITASSMSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTP 69

Query: 897  LDNKTATTEVRESWLLTKLVKTTPRSSYNEMTEMFNFNHTYVAHWTSETSEGISAGSPTS 956
                + TT V  S      + TT  +     T     + T  A      S   +AGS T+
Sbjct: 70   SPTGSQTTIVSISG---SEITTTSTAGSENTTVSSAGSGTTTASMAGSESTISTAGSETT 126

Query: 957  -----GSTHIFGEPLGASTTRISETSFSTTPTD----RTATSLSDGILPPQPTAAHSSAT 1007
                 G+       +G+ TT  S TS  TT T      T T  + G        A S  T
Sbjct: 127  TVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETT 186

Query: 1008 PVPVT--HMFSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVP 1065
                T   M ++   GS  +   T    SE +T++ A S +     +   +TT +TA   
Sbjct: 187  AASTTGSEMTTVFTAGSETITPST--AGSETTTVSTAGSETTTVSTTGSETTTASTA--- 241

Query: 1066 PLDQTASTTIVIVPTHGDLIRTTSEATVISVRKTSMAVPSLTETPFHSLRLSTPVTAKAE 1125
              + TA++T+    T    + T    T +S   +     S  ++  ++       T  A 
Sbjct: 242  HSETTAASTMGSETTK---VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTAS 298

Query: 1126 TTLFSTSVDTVTPSTHTLVCSKPPPDNIPPASSTHVISTTSTPEATQPISQVEETSTYAL 1185
            TT F T+  + T S  T+  +           S   +++T  PE T+  +   E +T   
Sbjct: 299  TTGFETTAASTTGSEPTMASTM---------GSETTMASTIGPETTKVSTASSEVTT--- 346

Query: 1186 SFPYTFSGGGVVASLATGTTETSVVD----ETTPSHISANKLTT--SVNSHISSSATYRV 1239
                 F+ G      +T  +ET+ V     ETT + I  ++ +T  +  S  ++++T   
Sbjct: 347  ----VFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGS 402

Query: 1240 HTPV-SIQLVTSTSVLSSDKDQMTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTD 1298
             T   S +   +T+V ++  +  T+S+  +  T   TE             G+    ++ 
Sbjct: 403  ETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTE-------------GSEMTAVST 449

Query: 1299 TGFPETTKISSHQTHSPSEIPLGTPSDGNLASSPTSGSTQITPTLTSSNTVGVHIP-EMS 1357
            T F ETT  S+      SEI + + SD    ++ T GS   T T   S T   +     +
Sbjct: 450  TVF-ETTTASTEG----SEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSET 504

Query: 1358 TSLGKTALPSQAL----TITTFLCPEKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDT 1413
            T+   T L +  +    + TT    E   T+A+ A       +    +  T   + G +T
Sbjct: 505  TTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSET 564

Query: 1414 SFVDTT----TSSSTRISNPMDINTTFSHLHSLRTQPEVTSVASFISESTQTFP----ES 1465
            + V TT    T++ST  S    ++TT +   +  T+   T+ AS     T T      E+
Sbjct: 565  TTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSEN 624

Query: 1466 LSLSTAGLYNDGFTVLSDRITTAFSVPNVPTMLPRESSMATSTPIYQMSSLPVNVTA--- 1522
             + STA       +      TTA +  +  T    E S  T+       +  V+ T    
Sbjct: 625  TTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSER 684

Query: 1523 -FTSKKVSDTPPI--------VITKSSKTMHPGCLKSPCTATSGPMSEMSSIPVNNSAFT 1573
              TS + S+T  +        V T+ S T       S  T  S   SE ++     S  T
Sbjct: 685  TITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEIT 744

Query: 1574 PATVSSDTSTRVGLFSTLLSSVTPRTTMTMQTSTLDVT--PVIYAGATSKNKMVSSAFTT 1631
             A+++   +T     ST  S  T  +T   +T++   T      A  TS    ++S   +
Sbjct: 745  TASITGSETTTA---STEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS 801

Query: 1632 EMIEAPSRITPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSPLSSKSTGAISSI 1691
            E   A +  + TT +S     +       TT+        + +T  S  ++ ST    +I
Sbjct: 802  ETTMASTIGSETTKVSTASSKM-------TTVFTENSETTIASTTASETTTVSTAGSETI 854

Query: 1692 PKTTF----------------------SPFLSATQQSSQADEATTLG------ILSGITN 1723
            P +T                       S   +A+ +SS+   ATT+G         G   
Sbjct: 855  PASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSET 914

Query: 1724 RSLSTVNSGTGVALTDTYSRITVPENMLSPTHADSLHTSFNIQVSPSLTSFKSASGPTKN 1783
             + ST  S T  A T+  S IT      S T   S   S     S   +   + S  T +
Sbjct: 915  TTTSTEGSETTTASTEG-SEITTVSTTGSETTTASTEGSETTTASTEGSELTTVS-TTGS 972

Query: 1784 VKTTTNCFSSNTRKMTSLLEKTSLTNYATSLNTPVSYPPWTPSSATLP-SLTSFVYSPHS 1842
               T +   S T  +T++  +T+  + A S  T VS      ++A++  S T+ V S  S
Sbjct: 973  ETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGS 1032

Query: 1843 TEAEISTPKTSPPPTSQMVEFPVLGTRMTSSNTQPLLMTSWNIPTAEGSQFPISTTINVP 1902
                +ST  T    TS   E     T  T+ +    + T+ +  T   ++   +TT++  
Sbjct: 1033 ETTTVSTTGTETTITS--TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTT 1090

Query: 1903 TSNEMETETLHLVPGPLSTFTASQTGLVSKDVMAMSSIPMSGILPNHGLSENPSLSTSLR 1962
             S      T  L    +ST + S T   S      +++ ++G       +E  S +T++ 
Sbjct: 1091 GSETTTASTADLETTTVST-SGSGTTTASTAGSETTTVYITGSKTTTASTEG-SEATTVS 1148

Query: 1963 AITSTLADVKHTFEKMT---TSVTPGTTLPSILSGATSGSVISKSPILTWLLSSLPSGSP 2019
              +S       T  +MT   T+V+  TT+ +I S AT+ S        T        GS 
Sbjct: 1149 TTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTT-----STEGSE 1203

Query: 2020 PATVSNAPHVMTSSTVEVSKSTFLT---SDMISAHPFTNLTTLPSATMSTILTRTI--PT 2074
              T S A    T+++   S++T  +   S+  +A    + T+ PS+  S   T  I    
Sbjct: 1204 TTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSE 1263

Query: 2075 PTLGGITTGFPTSLPMSINVTDDIVYISTHPEASSRTTITANPRTVSHPSSFSRKTMSPS 2134
             T+    +  PT+  ++ + T  +   ++   A+S TT+++    ++  +  S + ++ +
Sbjct: 1264 TTIASTASLEPTATSLTGSETTTVSITASGATAAS-TTVSSTTFVLTKATDVSIQPITNT 1322

Query: 2135 TTDHTLSVGAMPLPSSTITSSWNRIPTASSPSTLIIPKPTLDSLLNIMTTTSTVPGASFP 2194
                T + G     SS++T +     TAS+ S  +   P +  +LN     ++  GAS  
Sbjct: 1323 PMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTV---PGI--VLNTSGLGTSTMGASST 1377

Query: 2195 LISTGVTYPFTATVSSPISSFFETT 2219
              + GV    T +   P SS F+ T
Sbjct: 1378 TSAHGVR-TTTGSTREPTSSTFQET 1401



 Score =  150 bits (378), Expect = 2e-35
 Identities = 260/1149 (22%), Positives = 443/1149 (38%), Gaps = 119/1149 (10%)

Query: 1224 TTSVNSHISSSATYRVHTPVSIQLVTSTSVLSSDKDQMTISLGKTPRTM-------EVTE 1276
            T++ +S + ++++    T V+    ++T+  S+   + T  L K   T        E T 
Sbjct: 9    TSTADSKVITASSMSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTT 68

Query: 1277 MSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSPSEIPLGTPSDGNLASSPTSGS 1336
             SP+ +     S     +  T T   E T +SS  + + +    G+ S  + A S T+ +
Sbjct: 69   PSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSESTISTAGSETT-T 127

Query: 1337 TQITPTLTSS-NTVGVHIPEMSTSLGKTALPSQALTITTFLCP-----------EKESTS 1384
              IT T T+  + +G      ST+  +T + S A + TT +             + E+T+
Sbjct: 128  VSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA 187

Query: 1385 ALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINTTFSHLHSLRT 1444
            A    +  T      S  +T S + G +T+ V T  S +T +S      TT S  HS   
Sbjct: 188  ASTTGSEMTTVFTAGSETITPSTA-GSETTTVSTAGSETTTVSTTGSETTTASTAHS--- 243

Query: 1445 QPEVTSVASFISESTQ--TFPESLSLSTAGLYNDGFTVLSDRITTAFSVPNVPTMLPRES 1502
              E T+ ++  SE+T+  T     ++STAG      +       TAF+          E 
Sbjct: 244  --ETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFT----------ED 291

Query: 1503 SMATSTPIYQMSSLPVNVTAFTSKKVSDT---PPIVITKSSKTMHPGCLKSPCTATSGPM 1559
            S  T+           + T F +   S T   P +  T  S+T     +    T  S   
Sbjct: 292  SKTTTA----------STTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTAS 341

Query: 1560 SEMSSI-PVNNSAFTPATVSSDTSTRVGLFSTLLSSVTPRTTMTMQTSTLDVTPVIYAGA 1618
            SE++++    +     +TV S+T+T     ST  S  T  + M  +TST   T       
Sbjct: 342  SEVTTVFAAGSETIRASTVGSETTT----VSTTGSETTTASIMGSETSTDSTT----GSE 393

Query: 1619 TSKNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFS 1678
            T+      S  TT   E     T +T  S T           TT   G     V TT F 
Sbjct: 394  TTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFE 453

Query: 1679 PLSSKSTGAISSIPKTTFSPFLSATQQSSQADEATTLG--ILSGITNRSLSTVNSGTGVA 1736
              ++ + G+  +I  T+ S   +A+ + S+    TT G    +  T  S +T  S TG+ 
Sbjct: 454  TTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLE 513

Query: 1737 LTDTYSRITVPENMLSPTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTR 1796
             T  ++       + S T   S   S    VS + +   + S       T +   S  T 
Sbjct: 514  TTTVFT-------IGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTT 566

Query: 1797 KMTSLLEKTSLTNYATSLNTPVSYPPWTPSSATLPSLTSFVYSPHSTEAEISTPKTSPPP 1856
              T+ LE T+ +   + + T  +    T + +T  S T+   +  S    +ST   S   
Sbjct: 567  VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTAD-SENT 625

Query: 1857 TSQMVEFPVLGTRMTSSNTQPLLMTSWNIPTA--EGSQFPISTTINVPTSNEMETETLHL 1914
            T+   +        T S T     TS    TA  EGS+    +T +  T+    T +   
Sbjct: 626  TASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERT 685

Query: 1915 VPGP--LSTFTASQTG---LVSKDVMAMSSIPMSGILPNHGLSENPSLSTSLRAITST-- 1967
            +       T T S TG    VS +    +++ ++G       SE   +ST+    T+T  
Sbjct: 686  ITSTEGSETTTVSATGSETTVSTEGSGTTTVSITG-------SETTKVSTTGSETTTTST 738

Query: 1968 ----LADVKHTFEKMTTSVTPGTTLPSILSGATSGSVISKSPILTWLLSSLPSGSPPATV 2023
                +     T  + TT+ T G+   +  +  +  +  S +   T   S+  S +  A++
Sbjct: 739  EGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASI 798

Query: 2024 SNAPHVMTSST-VEVSKSTFLTSDMISAHPFTNLTTLPSAT------MSTILTRTIPTPT 2076
              +   M S+   E +K +  +S M +     + TT+ S T      +ST  + TIP  T
Sbjct: 799  MGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAST 858

Query: 2077 LGGITTGFPTSLPMSINVTDDIVYISTHPEASSRTTITANPRTVSHPSSFSRKTMSPSTT 2136
             G  TT        +   T+     +   E S  TT +      +  ++   +T + ST 
Sbjct: 859  AGSETT--------TTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTE 910

Query: 2137 -DHTLSVGAMPLPSSTITSSWNRIPTASSPSTLIIPKPTLDSLLNIMTTTSTVPGASFPL 2195
               T +       ++T ++  + I T S+  +    + T  S     TTT++  G+    
Sbjct: 911  GSETTTTSTEGSETTTASTEGSEITTVSTTGS----ETTTASTEGSETTTASTEGSELTT 966

Query: 2196 ISTGVTYPFTATVSSPISSFFETTWLDSTPSFLSTEASTSPTATK--STVSFYNVEMSFS 2253
            +ST  T   T TVS+  S     T + S  +  ST  S + T +   S  +  ++E S +
Sbjct: 967  VST--TGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSET 1024

Query: 2254 VFVEEPRIPITSVINEFTENSLNSIFQNSEFSLATLETQIKSRDISEEEMVMDRAILEQR 2313
              V       T+V    TE ++ S   +   ++ T  ++  +   +  E           
Sbjct: 1025 TTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSE-----TTTTST 1079

Query: 2314 EGQEMATIS 2322
            EG E  T+S
Sbjct: 1080 EGSETTTVS 1088



 Score =  145 bits (367), Expect = 5e-34
 Identities = 290/1196 (24%), Positives = 467/1196 (39%), Gaps = 115/1196 (9%)

Query: 1082 GDLIRTTSEATVISVRKTSMAVPSLTETPFHSLRLSTPVTAKAETTLFSTSVDTVTPSTH 1141
            G    TTS A    +  +SM+  +       S   +   T    TT+   + +T T ST 
Sbjct: 3    GSEATTTSTADSKVITASSMSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTA 62

Query: 1142 TLVCSKPPPDNIPPASSTHVISTTSTPEATQPISQVEETS-TYALSFPYTFSGGGVVASL 1200
                + P P      S T ++S + +   T   +  E T+ + A S   T S  G  +++
Sbjct: 63   GSETTTPSPTG----SQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSESTI 118

Query: 1201 ATGTTETSVVD--ETTPSHISANKLTTSVNSHISSSATYRVHTPVSIQLVTSTSVLSSDK 1258
            +T  +ET+ V    T  + +SA    T+ NS  SS  T           VTST+      
Sbjct: 119  STAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETT-----------VTSTA----GS 163

Query: 1259 DQMTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSPSEI 1318
            +  T+S   +  T   T  S +       +  T   EMT      T   +  +T +PS  
Sbjct: 164  ETTTVSTVGSETTTAYTADSETT------AASTTGSEMT------TVFTAGSETITPSTA 211

Query: 1319 PLGTPSDGNLASSPTSGSTQITPTLTSSNTVGVHIPEMSTSLGKTALPSQALTITTFLCP 1378
               T +     S  T+ ST  + T T+S T        ST   +T   S A + TT    
Sbjct: 212  GSETTTVSTAGSETTTVSTTGSETTTAS-TAHSETTAASTMGSETTKVSTAGSETTVSTA 270

Query: 1379 EKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINTTFSH 1438
              E+T+A       T +   N+ +   S +    T+  +TT +S+T  S P   +T  S 
Sbjct: 271  GSETTAA------STEDSETNTAFTEDSKTTTASTTGFETTAASTTG-SEPTMASTMGSE 323

Query: 1439 LHSLRT-QPEVTSVASFISESTQTFP---ESLSLSTAGLYNDGFTVLSDRITTAFSVPNV 1494
                 T  PE T V++  SE T  F    E++  ST G      +      TTA S+   
Sbjct: 324  TTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTA-SIMGS 382

Query: 1495 PTMLPRESSMATSTPIYQMSSLPVNVTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTA 1554
             T     +   T+T   + S      TA T    + T   V T  S+T       S  T 
Sbjct: 383  ETSTDSTTGSETTTASTEGSE---TTTASTEGSEATT---VSTTGSETTTVSITDSETTT 436

Query: 1555 TSGPMSEMSSIPVNNSAFTPATVSSDTSTRVGLFSTLLSSVTPRTTMTMQTSTLDVTPVI 1614
            T    SEM++  V+ + F   T S++ S         ++S +   T T  T   + T V 
Sbjct: 437  TCTEGSEMTA--VSTTVFETTTASTEGS------EITIASTSDSETTTASTEGSETTTVT 488

Query: 1615 YAGATSKNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGT 1674
             AG+ +K    + + TT         T T F   ++ T    +   TT ++   +    T
Sbjct: 489  TAGSETKTAYTTGSETTTASNTGLETT-TVFTIGSDTTTASTEGSETTAVSATGSEM--T 545

Query: 1675 TAFSPLSSKSTGAISSIPKTTFSPF-LSATQQSSQADEATTLGILSGITNRSLSTVNSGT 1733
            T  +  S  +T + +    TT S   L  T  S++  E TT+   +G    + ST  SGT
Sbjct: 546  TVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVST-TGAETTTDSTEGSGT 604

Query: 1734 GVALTDTYSRITVP----ENMLSPTHADSLHTSFNIQVSP----SLTSFKSASGPTKNVK 1785
              A T      TV     EN  + T ADS  TS +   S     S TS ++ +  T+  +
Sbjct: 605  TAASTAGSETTTVSTADSENTTAST-ADSETTSASTTGSETTTASTTSSETTTASTEGSE 663

Query: 1786 TTT-NCFSSNTRKMTSLLEKTSLTNYATSLNTPVSYPPWTPSSATLPSLTSFVYSPHSTE 1844
            TTT +   S T  +++   + ++T+   S  T VS      + +T  S T+ V    S  
Sbjct: 664  TTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSET 723

Query: 1845 AEISTPKTSPPPTS----QMVEFPVLGTRMTSSNTQPLLMTSWNIPTAEGSQFPISTTIN 1900
             ++ST  +    TS    ++    + G+  T+++T+    T+    + EGS+    TT  
Sbjct: 724  TKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT---ASTEGSE----TTSA 776

Query: 1901 VPTSNEMETETLHLVPGPLSTFTASQTGLVSKDVMAMSSIPMSGILPNHGLSENPSLSTS 1960
              T +E  T +       +++   S+T + S      + +  +        +EN     S
Sbjct: 777  STTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTEN-----S 831

Query: 1961 LRAITSTLADVKHTFEKMTTSVTPGTTLPSILSGATSGSVISKSPILTWLLSSLPSGSPP 2020
               I ST A      E  T S     T+P+  +G+ + +  S     T   S+   GS  
Sbjct: 832  ETTIASTTAS-----ETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTAST--EGSET 884

Query: 2021 ATVSNAPHVMTSSTVEVSKSTFLT---SDMISAHPFTNLTTLPSA------TMSTILTRT 2071
             T S      T++T   S++T  +   S+  +     + TT  S       T+ST  + T
Sbjct: 885  TTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSET 944

Query: 2072 IPTPTLGGITTGFPTSLPMSINV-TDDIVYISTHPEASSRTTITANPRTVSHPSSFSRKT 2130
                T G  TT   T       V T     I+   E S  TT+T      +  S+   +T
Sbjct: 945  TTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSET 1004

Query: 2131 MSPSTT-DHTLSVGAMPLPSSTITSSWNRIPTASSPSTLIIPKPTLDSLLNIMTTTSTVP 2189
             + ST    T +       ++T++S+ +   T S+  T    + T+ S     TTT T  
Sbjct: 1005 TTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGT----ETTITSTEGSETTTVTTA 1060

Query: 2190 GASFPLI-STGVTYPFTATVSSPISSFFETTWLDSTPSFLSTEASTSPTATKSTVS 2244
            G+    + +TG     T+T  S  ++   T    +T S    E +T  T+   T +
Sbjct: 1061 GSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTT 1116



 Score = 88.2 bits (217), Expect = 1e-16
 Identities = 148/643 (23%), Positives = 235/643 (36%), Gaps = 78/643 (12%)

Query: 219  IPTVDRTLRCFVPENMTIQEKSTTVSQQIDMTTPSQITGVKPQNTAHSSTLLSQSIPIFA 278
            + T    +     EN      STT S+   ++T    T   P +TA S T  + S     
Sbjct: 816  VSTASSKMTTVFTENSETTIASTTASETTTVSTAGSET--IPASTAGSETTTTTSTEGSE 873

Query: 279  TDYTTISYSNTTSPPL---ETMTAQKI------LKTLVDETATFAVDVLSTSSAISLPTQ 329
            T   +   S TT+      ET TA  I        T   ET T + +   T++A    T+
Sbjct: 874  TTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTA---STE 930

Query: 330  SISIDNTTNSMKKTKSPSSESTKTTKMVEAMATEIFQPPTPSNFLSTSRFTKNSVVSTTS 389
               I   + +  +T + S+E ++TT      +TE  +  T S        T  S   T S
Sbjct: 931  GSEITTVSTTGSETTTASTEGSETT----TASTEGSELTTVS--------TTGSETITVS 978

Query: 390  AIKSQSAVTKTTSLFSTIESTSMSTTPCLKQKSTNTGALPISTAGQEFIESTAAGTVPWF 449
            A  S++    T    +T  ST+ S T              +STAG E   ++  G+    
Sbjct: 979  AEGSETTTVTTMGSETTTASTAGSET------------TTVSTAGSETTTASIEGS-ETT 1025

Query: 450  TVEKTSPASTHVGTASSFPPEPVLISTAAPVDSVFPRNQTAFPLATTDMKIAFTVHSLTL 509
            TV  T   +T V T            T   + S      T    A ++    +T  S T 
Sbjct: 1026 TVSSTGSETTTVSTT----------GTETTITSTEGSETTTVTTAGSETTAVYTTGSET- 1074

Query: 510  PTRLIETTPAPRTAETELTSTNFQDVSLPRVEDAMSTSMSKETSSKTFSFLTSFSFTGTE 569
                  TT +   +ET   ST   + +     D  +T++S   S       T+ S  G+E
Sbjct: 1075 ------TTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG-----TTTASTAGSE 1123

Query: 570  SVQTVIDAEATRTALTPEITLASTVAETMLSSTITGRVYTQNTPTADGHLLTLMSTRSAS 629
            +    I    T TA T E + A+TV+ T   +T         T +  G  +T + T  + 
Sbjct: 1124 TTTVYITGSKTTTAST-EGSEATTVSTTSSETT---------TASTTGSEMTTVFTTVSE 1173

Query: 630  TSKAPESGPTSTTDEAAHLFSSNETIWTSRPDQALLASMNTTTILTFVPNENFTSAFHEN 689
            T+     G  +TT  AA   ++  +   S    A  A   TTT  T   +E  T++   +
Sbjct: 1174 TTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAST-AGSETTTASTSGS 1232

Query: 690  TTYTEYLSATTNITPLKASPEGK-----GTTANDATTARYTTAVSKLTSPWFANFSIVSG 744
             T T   + +   TP  A  E       G+    A+TA      + LT       SI + 
Sbjct: 1233 ETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITAS 1292

Query: 745  TTSITNMPEFKLTTLLLKTIPMSTKPANELPLTPRETVVPSVDIISTLACIQPNFSTEES 804
              +  +      T +L K   +S +P    P++   T    +   S++        T  +
Sbjct: 1293 GATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASA 1352

Query: 805  ASETTQTEINGAIVFGGTTTPVPKSATTQRLNATV-TRKEATS 846
            AS T    +      G +T     + +   +  T  + +E TS
Sbjct: 1353 ASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPTS 1395


>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score =  201 bits (511), Expect = 9e-51
 Identities = 352/1539 (22%), Positives = 585/1539 (38%), Gaps = 175/1539 (11%)

Query: 343  TKSPSSESTKTTKMVEAMATEIFQP-------PTPSNFLSTSRFTKNSVVSTTSAIKSQS 395
            T + ++ S  TT +++A  T            P+P+   +T      S ++TTS   S++
Sbjct: 16   TTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSEN 75

Query: 396  AVTKTTSLFSTIESTSMSTTPCLKQKSTNTGALPISTAGQEFIESTAAGTVPWFTVEKTS 455
                     +T+ S    TT      S  T    +STAG E    +  GT         S
Sbjct: 76   ---------TTVSSAGSGTTTASMAGSETT----VSTAGSETTTVSITGTETTMVSAMGS 122

Query: 456  PASTHVGTASSFPPEPVLISTAAPVDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIE 515
              +T+  T+S         S    V +V     TA+   +     + T   +T       
Sbjct: 123  ETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGS 182

Query: 516  TTPAPRTAETELTSTNFQDVSLPRVEDAMSTSMSKETSSKTFSFLTSFSFTGTESVQ-TV 574
             T  P TA +E T+ +        V    +T     T+S   S  T+ S  G+E+ + + 
Sbjct: 183  ETITPSTAGSETTTVSTAGSETTTVS---TTGSETTTASTAHSETTAASTMGSETTKVST 239

Query: 575  IDAEATRTALTPEITLASTV-AETMLSSTITGRVYTQNT-------PTADGHLLTLMSTR 626
              +E T +    E T AST  +ET  + T   +  T +T        +  G   T+ ST 
Sbjct: 240  AGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTM 299

Query: 627  SASTSKAPESGPTSTTDEAAHLFSSNETIWTSRPDQALLASM--NTTTILTFVPNENFTS 684
             + T+ A   GP +T    A   SS  T   +   + + AS   + TT ++   +E  T+
Sbjct: 300  GSETTMASTIGPETTKVSTA---SSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTA 356

Query: 685  AFHENTTYTEYLSATTNITPLKASPEGKGTTANDATTARYTTAVSKLTSPWFANFSIVSG 744
            +   + T T+   +TT      AS EG  TT      +  TT             S    
Sbjct: 357  SIMGSETSTD---STTGSETTTASTEGSETTTASTEGSEATTV------------STTGS 401

Query: 745  TTSITNMPEFKLTTLLLKTIPMSTKPANELPLTPRETVVPSVDIISTLACIQPNFSTEES 804
             T+  ++ + + TT   +   M+         T   T    + I ST        STE S
Sbjct: 402  ETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGS 461

Query: 805  ASETTQTEINGAIVFGGTTTPVPKSATTQRLNATVTRKEATSHYLMRKSTIAAVAEVSPF 864
             + T  T         G+ T    +  ++   A+ T  E T+ + +   T  A  E S  
Sbjct: 462  ETTTVTT--------AGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 513

Query: 865  -------STMLEVTDESAQRVTASVTVSSFPDIEKLSTPLDNKTATTEVRESWLLTKLVK 917
                   S M  V+ E ++  T S T S    +   +T L+  T +TE  E       V 
Sbjct: 514  TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVS--TTGLETTTTSTEGSE----MTTVS 567

Query: 918  TTPRSSYNEMTEMFNFNHTYVAHWTSETSEGISAGSPTSGSTHIFGEPLGASTTRISETS 977
            TT   +  + TE      T  +   SET+   +A S  + ++    E   ASTT  SET+
Sbjct: 568  TTGAETTTDSTE--GSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTG-SETT 624

Query: 978  FSTTPTDRTATSLSDGILPPQPTAAHSSATPVPVTHMFSLPVNGSSVVAEETEVTMSEPS 1037
             ++T +  T T+ ++G          S  T V  T               ++E TM   +
Sbjct: 625  TASTTSSETTTASTEG----------SETTTVSTT---------------DSETTMVSTT 659

Query: 1038 TLARAFSTSVLSDVSNLSSTTMTTALVPPLDQTASTTIVIVPTHGDLIRTT-SEATVISV 1096
               R  +++  S+ + +S+T   T +    + + +TT+ I  +    + TT SE T  S 
Sbjct: 660  GSERTITSTEGSETTTVSATGSETTV--STEGSGTTTVSITGSETTKVSTTGSETTTTST 717

Query: 1097 RKTSMAVPSLTETPFHSLRLSTPVTAKAETTLFSTSVDTVTPSTHTLVCSKPPPDNIPPA 1156
              + +   S+T +       +T  T  +ETT  ST   + T S  T              
Sbjct: 718  EGSEITTASITGS-----ETTTASTEGSETTTASTE-GSETTSASTTGSETTTASTTSSE 771

Query: 1157 SSTHVISTTSTPEATQPISQVEETSTYALSFPYTFSGGGVVASLATGTTETSVV----DE 1212
            ++   I  + T  A+   S+  + ST +      F+        +T  +ET+ V     E
Sbjct: 772  TTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831

Query: 1213 TTPSHISANKLTTSVNSHISSSATYRVH----TPVSIQLVTSTSVLSSDKDQMTISLGKT 1268
            T P+  + ++ TT+ ++  S + T        T  S +   +T+  +   +  T S   +
Sbjct: 832  TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS 891

Query: 1269 PRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSPSEIPLGTPSDGNL 1328
              T   TE S +     + + G+    ++ TG  ETT  S+      SE    +     L
Sbjct: 892  ETTTTSTEGSETTT---ASTEGSEITTVSTTG-SETTTAST----EGSETTTASTEGSEL 943

Query: 1329 ASSPTSGSTQITPT-----LTSSNTVGVHIPEMSTSLGKTALPSQALTITTFLCPEKEST 1383
             +  T+GS  IT +      T+  T+G      ST+  +T   S A + TT    E   T
Sbjct: 944  TTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSET 1003

Query: 1384 SALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINTTFSHLHSLR 1443
            + + +    T  +    T  T + + G +T+ V T  S +T +       TT S   S  
Sbjct: 1004 TTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGS-- 1061

Query: 1444 TQPEVTSVASFISESTQTFPESLSLSTAGLYNDGFTVLS---DRITTAFSVPNVPTMLPR 1500
               E T+V++  SE+T      L  +T      G T  S      TT +   +  T    
Sbjct: 1062 ---ETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTAST 1118

Query: 1501 ESSMATSTPIYQMSSLPVNVTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTATSGPMS 1560
            E S AT+      ++     TA T+     T   V T  S+T     + S  T +S   S
Sbjct: 1119 EGSEATTV----STTSSETTTASTTGSEMTT---VFTTVSETTTVSTIGSEATTSSAAGS 1171

Query: 1561 EMSSIPVNNSAFTPA-TVSSDTSTRVGLFSTLLSSVTPRTTMTMQTSTLDVTPVIYAGAT 1619
            E ++     S  T A T  S+T+T     ST  S  T  +T   +T+T   T    +  +
Sbjct: 1172 EATTTSTEGSETTTASTAGSETTTA----STAGSETTTASTSGSETNTACTTGSETSTPS 1227

Query: 1620 SKNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSP 1679
            S     ++AF   +I + S I  T  L PT  +L   +T   +I A       G TA S 
Sbjct: 1228 SAGSETNTAF---IIGSESTIASTASLEPTATSLTGSETTTVSITAS------GATAAST 1278

Query: 1680 LSSKSTGAISSIPKTTFSPFLSATQQSSQADEATTLGILSGITNRSLSTVNSGTGVALTD 1739
              S +T  ++     +  P  +     ++          +G    + S+V    G+  T 
Sbjct: 1279 TVSSTTFVLTKATDVSIQPITNTPMSGTRT---------TGTRLTASSSVTMAPGMDFTA 1329

Query: 1740 TYSRITVPENMLSPTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMT 1799
            + +  TVP  +L   +   L TS     + S TS       T + +  T+     T  ++
Sbjct: 1330 SAASHTVPGIVL---NTSGLGTS--TMGASSTTSAHGVRTTTGSTREPTSSTFQETGPVS 1384

Query: 1800 SLLEKTSLTNYATSLNTPVSY-PPWTPSSATLPSLTSFV 1837
                  S+++  T++  P  Y  PW     +L ++ + V
Sbjct: 1385 MGTNTVSMSHTPTNVIKPSGYLQPWAIILISLAAVVAAV 1423



 Score =  194 bits (494), Expect = 9e-49
 Identities = 356/1506 (23%), Positives = 591/1506 (39%), Gaps = 195/1506 (12%)

Query: 235  TIQEKSTTVSQQIDMTTPSQITGVKPQ-NTAHSSTLLSQSIPIFATDYTTIS-YSNTTSP 292
            T   ++TTVS     TT + + G +   +TA S T    ++ I  T+ T +S   + T+ 
Sbjct: 70   TAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETT---TVSITGTETTMVSAMGSETTT 126

Query: 293  PLETMTAQKILKTLVDETATFAVDVLSTSSAISLPTQSISIDNTTNSM-------KKTKS 345
               T +   +  T   ET T +     T++A +  +++ +   T + M        +T +
Sbjct: 127  NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETIT 186

Query: 346  PSSESTKTTKMVEAMATEIFQPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFS 405
            PS+  ++TT +  A +       T S   +T+  T +S  +  S + S++    T    +
Sbjct: 187  PSTAGSETTTVSTAGSETTTVSTTGSE--TTTASTAHSETTAASTMGSETTKVSTAGSET 244

Query: 406  TIESTSMSTTPCLKQKS-TNTGALPIS---TAGQEFIESTAAGTVPWFTVEKTSPAST-- 459
            T+ +    TT    + S TNT     S   TA     E+TAA T    T  + + AST  
Sbjct: 245  TVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST----TGSEPTMASTMG 300

Query: 460  -HVGTASSFPPEPVLISTAAP-VDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETT 517
                 AS+  PE   +STA+  V +VF         +T   +      + T+ T   ETT
Sbjct: 301  SETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSE------TTTVSTTGSETT 354

Query: 518  PAP-RTAETELTSTNFQDVSLPRVEDAMSTSMSKETSSKTFSFLTSFSFTGTESVQTVID 576
             A    +ET   ST   + +    E + +T+ S E S  T     + S TG+E+    I 
Sbjct: 355  TASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEAT-----TVSTTGSETTTVSIT 409

Query: 577  AEATRTALTP--EITLASTVAETMLSSTITGRVYTQNTPTADGHLLTLMSTRSASTSKAP 634
               T T  T   E+T  ST             V+   T + +G  +T+ ST  + T+ A 
Sbjct: 410  DSETTTTCTEGSEMTAVSTT------------VFETTTASTEGSEITIASTSDSETTTAS 457

Query: 635  ESGPTSTTDEAAHLFSSNETIWT--SRPDQALLASMNTTTILTFVPNENFTSAFHENTTY 692
              G  +TT   A   S  +T +T  S    A    + TTT+ T     + T+A  E +  
Sbjct: 458  TEGSETTTVTTAG--SETKTAYTTGSETTTASNTGLETTTVFTI--GSDTTTASTEGSET 513

Query: 693  TEYLSATTNITPLKASPEGK-----GTTANDATTARYTTAVSKLTSPWFANFSIVS--GT 745
            T   +  + +T +  S EG       TT ++ TT   T   +  TS   +  + VS  G 
Sbjct: 514  TAVSATGSEMTTV--STEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGA 571

Query: 746  TSITNMPEFKLTTLL----LKTIPMSTKPANELPLTPRETVVPSVDIISTLACIQPNFST 801
             + T+  E   TT       +T  +ST  +         T   + D  +T A       +
Sbjct: 572  ETTTDSTEGSGTTAASTAGSETTTVSTADS-------ENTTASTADSETTSA---STTGS 621

Query: 802  EESASETTQTEINGAIVFGGTTTPVPKS-ATTQRLNATVTRKEATSHYLMRKSTIAAVAE 860
            E + + TT +E   A   G  TT V  + + T  ++ T + +  TS      +T++A   
Sbjct: 622  ETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGS 681

Query: 861  VSPFSTMLEVTDESAQRVTASVTVSSFPDIEKLSTPLDNKTATTEVRESWLLTKLV---K 917
             +  ST      E +   T S+T S   +  K+ST   ++T TT    S + T  +   +
Sbjct: 682  ETTVST------EGSGTTTVSITGS---ETTKVST-TGSETTTTSTEGSEITTASITGSE 731

Query: 918  TTPRSSYNEMTEMFNFNHTYVAHWTSETSEGISAGSPTS--------GSTHIFGEPLGAS 969
            TT  S+    T   +   +     ++  SE  +A + +S        GS       +G+ 
Sbjct: 732  TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSE 791

Query: 970  TTRISETS--FSTTPTDRTATSLSDGILPPQPTAAHSSATPVPVTHMFSLPVNGSSVVAE 1027
            TT++S  S   +T  T+ + T+++        T + + +  +P +   S     +S    
Sbjct: 792  TTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGS 851

Query: 1028 ETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVPPLDQTASTTIVIVPTHGDLIRT 1087
            ET    +E S    A + S  +  +    +  TTA     + T ++T             
Sbjct: 852  ETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTST------------E 899

Query: 1088 TSEATVISVRKTSMAVPSLT--ETPFHSLRLSTPVTAKAE----TTLFSTSVDTVTPS-- 1139
             SE T  S   + +   S T  ET   S   S   TA  E    TT+ +T  +T+T S  
Sbjct: 900  GSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAE 959

Query: 1140 -THTLVCSKPPPDNIPPASSTHVISTTSTPEATQPISQVEETSTYALSFPYTFSGGGVVA 1198
             + T   +    +    +++    +T ST  +    + +E + T  +S   T S    V+
Sbjct: 960  GSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVS--STGSETTTVS 1017

Query: 1199 SLATGTTETSVVDETTPSHISANKLTTSVNSHISSSATYRVH----TPVSIQLVTSTSVL 1254
            +  T TT TS     T +  +A   TT+V +  S + T        T VS     +T+  
Sbjct: 1018 TTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAS 1077

Query: 1255 SSDKDQMTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHS 1314
            ++D +  T+S   +  T   T  S +   +I+ S+ T +     T   E T +S+     
Sbjct: 1078 TADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTA----STEGSEATTVST----- 1128

Query: 1315 PSEIPLGTPSDGNLASSPTSGSTQITPTLTSSNTVGVHIPEMSTSLGKTALPSQALTITT 1374
                   T S+   AS+  S  T +  T++ + TV     E +TS   +A  S+A T +T
Sbjct: 1129 -------TSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTS---SAAGSEATTTST 1178

Query: 1375 FLCPEKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINT 1434
                  E+T+A  A +  T      S   T S S  +  +   T + +ST  S   + NT
Sbjct: 1179 ---EGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNT 1235

Query: 1435 TFSHLHSLRTQPEVTSVASFISESTQTFPESLSLSTAGLYNDGFTVLSDRITTAFSVPNV 1494
             F     + ++  + S AS   E T T       +T  +   G T  S   TT  S   V
Sbjct: 1236 AF----IIGSESTIASTASL--EPTATSLTGSETTTVSITASGATAAS---TTVSSTTFV 1286

Query: 1495 PTMLPRESSMATSTPIYQMSSLPVNVTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTA 1554
             T        AT   I  +++ P++ T  T  +++         SS TM PG        
Sbjct: 1287 LT-------KATDVSIQPITNTPMSGTRTTGTRLT-------ASSSVTMAPGM----DFT 1328

Query: 1555 TSGPMSEMSSIPVNNSAFTPATVSSDTSTRVGLFSTLLSSVTPRTTMTMQTSTLDVTPVI 1614
             S     +  I +N S    +T+ + ++T      T   S    T+ T Q    +  PV 
Sbjct: 1329 ASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPTSSTFQ----ETGPVS 1384

Query: 1615 YAGATSKNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGT 1674
                T     VS + T   +     I P+ +L P    L  +  V   +   +   F   
Sbjct: 1385 MGTNT-----VSMSHTPTNV-----IKPSGYLQPWAIILISLAAVVAAVGLSVGLSFCLR 1434

Query: 1675 TAFSPL 1680
              F PL
Sbjct: 1435 NLFFPL 1440



 Score =  190 bits (483), Expect = 2e-47
 Identities = 344/1546 (22%), Positives = 588/1546 (38%), Gaps = 183/1546 (11%)

Query: 249  MTTPSQITGVKPQNTAHSSTLLSQSIPIF--ATDYTTISYSNT-TSPPLETMTAQKILKT 305
            M++ + +      NT  +ST  S++  I   A++ TT S + + T+ P  T +   I+  
Sbjct: 1    MSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSI 60

Query: 306  LVDETATFAVDVLSTSSAISLPTQSISIDNTTNSMKKTKSPSSESTKTTKMVEAMATEIF 365
               E  T      ST+ + +    S     TT SM       SE+T +T   E     I 
Sbjct: 61   SGSEITT-----TSTAGSENTTVSSAGSGTTTASMA-----GSETTVSTAGSETTTVSIT 110

Query: 366  QPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFSTIESTSMSTTPCLKQKSTNT 425
               T       S  T NS  S+ + + S +    TT      E+T+  T       ++ T
Sbjct: 111  GTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTT 170

Query: 426  GA--LPISTAGQEFIESTAAGTVPWFTVEKTSPASTHVGTASSFPPEPVLISTAAPVDSV 483
            G+    + TAG E I  + AG+         S A +   T S+   E    STA      
Sbjct: 171  GSEMTTVFTAGSETITPSTAGS----ETTTVSTAGSETTTVSTTGSETTTASTA------ 220

Query: 484  FPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETTPAPRTAETELTSTNFQDVSLPRVEDA 543
                  A  + +   K++      T+ T   ETT     A TE + TN       +   A
Sbjct: 221  HSETTAASTMGSETTKVSTAGSETTVSTAGSETT----AASTEDSETNTAFTEDSKTTTA 276

Query: 544  MSTSMSKETSSKTFSFLTSFSFTGTE-SVQTVIDAEATR--TALTPEITLASTVAETMLS 600
             +T      +S T S  T  S  G+E ++ + I  E T+  TA +   T+ +  +ET+ +
Sbjct: 277  STTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRA 336

Query: 601  STITGRVYTQNTPTADGHLLTLMSTRSASTSKAPESGPTSTTDEAAHLFSSNE-----TI 655
            ST+     T +T  ++    ++M + +++ S       T++T+ +    +S E     T+
Sbjct: 337  STVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTV 396

Query: 656  WTSRPDQALLASMNTTTILTFVPNENFTSAFHENTTYTEYLSATTNITPLKASPEGKGTT 715
             T+  +   ++  ++ T  T       T+    +TT  E  +A+T  + +  +      T
Sbjct: 397  STTGSETTTVSITDSETTTTCTEGSEMTAV---STTVFETTTASTEGSEITIASTSDSET 453

Query: 716  ANDATTARYTTAVSKLTSPWFANFSIVSGTTSITNMPEFKLTTLLLKTIPMSTKPANELP 775
               +T    TT V+   S     ++  S TT+ +N     L T  + TI   T  A+   
Sbjct: 454  TTASTEGSETTTVTTAGSETKTAYTTGSETTTASNT---GLETTTVFTIGSDTTTASTEG 510

Query: 776  LTPRETVVPSVDIISTLACIQPNFSTEESASETTQTEINGAIVFGGTTTPVPKSATTQRL 835
                       ++ +       N +   + SETT     G      TTT    S  T   
Sbjct: 511  SETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG---LETTTTSTEGSEMT--- 564

Query: 836  NATVTRKEATSHYLMRKSTIAAVAEVSPFSTMLEVTDESAQRVTA-SVTVSSFPDIEKLS 894
              + T  E T+       T AA    S  +T+     E+    TA S T S+     + +
Sbjct: 565  TVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETT 624

Query: 895  TPLDNKTATTEVRESWLLTKLVKTTPRSSYNEMTEMFNFNHTYVAHWTSETSEGISAGSP 954
            T     + TT        T  V TT   S   M        T  +   SET+   + GS 
Sbjct: 625  TASTTSSETTTASTEGSETTTVSTT--DSETTMVSTTGSERTITSTEGSETTTVSATGSE 682

Query: 955  TSGSTHIFGEPLGASTTRISETSFSTTPTDRTATSLSDGILPPQPTAAHSSATPVPVTHM 1014
            T+ ST       G+ TT +S T   TT    T +         + T   +  + +    +
Sbjct: 683  TTVSTE------GSGTTTVSITGSETTKVSTTGS---------ETTTTSTEGSEITTASI 727

Query: 1015 FSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVPPLDQTASTT 1074
                   +S    ET    +E S    A +T   +  ++ +S+  T A +   + T ++T
Sbjct: 728  TGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAST 787

Query: 1075 IVIVPTHGDLIRTTSEATVISVRKTSMAVPSLTETPFHSLRLSTPVTAKAETTLFSTSVD 1134
            I             SE T +S                 S +++T  T  +ETT+ ST+  
Sbjct: 788  I------------GSETTKVSTA---------------SSKMTTVFTENSETTIASTT-- 818

Query: 1135 TVTPSTHTLVCSKPPPDNIPPA---SSTHVISTTSTPEATQPISQVEETSTYALSFPYTF 1191
                ++ T   S    + IP +   S T   ++T   E T   ++  ET+T +     T 
Sbjct: 819  ----ASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETT 874

Query: 1192 SGGGVVASLATGTTETSVVDETTPSHISANKLTT--SVNSHISSSATYRVHTPVSIQLVT 1249
            +   + +   T +TE S   ETT +    ++ TT  +  S I++ +T    T  +    +
Sbjct: 875  TATTIGSETTTASTEGS---ETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGS 931

Query: 1250 STSVLSSDKDQMTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISS 1309
             T+  S++  ++T        T+  T              G+ ++ ++  G  ETT +  
Sbjct: 932  ETTTASTEGSELT--------TVSTT--------------GSETITVSAEG-SETTTV-- 966

Query: 1310 HQTHSPSEIPLGTPSDGNLASSPTSGSTQITPTLTSSNTVGVHIPEMSTSLGKTALPSQA 1369
              T   SE    + +     +  T+GS   T ++  S T  V     S++  +T   S  
Sbjct: 967  --TTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTV-----SSTGSETTTVSTT 1019

Query: 1370 LTITTFLCPEKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSSTRISNP 1429
             T TT    E   T+ +      T  +    +  T + + G +T+ V TT S +T  S  
Sbjct: 1020 GTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST- 1078

Query: 1430 MDINTTFSHLHSLRTQPEVTSVASFISESTQTF----PESLSLSTAGLYNDGFTVLSDRI 1485
             D+ TT     ++ T    T+ AS     T T      ++ + ST G      +  S   
Sbjct: 1079 ADLETT-----TVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSET 1133

Query: 1486 TTAFS----VPNVPTMLPRESSMATSTPIYQMSSLPVNVTAFTSKKVSDTPPIVITKSSK 1541
            TTA +    +  V T +   ++++T       SS   +    TS + S+T       S  
Sbjct: 1134 TTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSET 1193

Query: 1542 TMHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPATVSSDTSTR--VGLFSTLLSSVTPRT 1599
            T          TA++      ++    +   TP++  S+T+T   +G  ST+ S+ +   
Sbjct: 1194 TTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEP 1253

Query: 1600 TMTMQTSTLDVTPVIYA-GATSKNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTLPFVKT 1658
            T T  T +   T  I A GAT+ +  VSS               TTF+  T+ T   ++ 
Sbjct: 1254 TATSLTGSETTTVSITASGATAASTTVSS---------------TTFVL-TKATDVSIQP 1297

Query: 1659 VPTTIMAGIVTPFVGTTAFSPLSS------KSTGAISSIPKTTF--SPFLSATQQSSQAD 1710
            +  T M+G  T     TA S ++        ++ A  ++P      S   ++T  +S   
Sbjct: 1298 ITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTT 1357

Query: 1711 EATTLGILSGITNRSLSTVNSGTGVAL--TDTYSRITVPENMLSPT 1754
             A  +   +G T    S+    TG     T+T S    P N++ P+
Sbjct: 1358 SAHGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNVIKPS 1403



 Score =  186 bits (471), Expect = 4e-46
 Identities = 344/1489 (23%), Positives = 577/1489 (38%), Gaps = 190/1489 (12%)

Query: 548  MSKETS--SKTFSFLTSFSFTGTESVQTVIDAEATRTALTPEITLASTVAETMLSSTITG 605
            MS ET+      S  T+ S TG+E+   +I A  T TA T         +ET        
Sbjct: 1    MSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAG-------SET-------- 45

Query: 606  RVYTQNTPTADGHLLTLMSTRSASTSKAPESGPTSTTDEAAHLFSSNETIWTSRPDQALL 665
                  TP+  G   T++S   +  +    +G  +TT  +A   ++  ++  S    +  
Sbjct: 46   -----TTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTA 100

Query: 666  ASMNTTTILTFVPNENFTSAFHENTTYTEYLSATTNITPLKASPEGKGTTANDATTARYT 725
             S  TT  +T        SA    TT     S+ T +T    S     +T    TT  Y 
Sbjct: 101  GSETTTVSITGT-ETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAY- 158

Query: 726  TAVSKLTSPWFANFSIVSGTTSITNMPEFKLTTLLLKTIPMSTKPANELPLTPRETVVPS 785
            TA S+ T+             S T      + T   +TI  ST  +     T   T    
Sbjct: 159  TADSETTA------------ASTTGSEMTTVFTAGSETITPSTAGSE---TTTVSTAGSE 203

Query: 786  VDIISTLACIQPNFSTEESASETTQTEINGAIVFGGTTTPVPKSATTQRLNATVTRKEAT 845
               +ST         +E + + T  +E   A   G  TT V             T    T
Sbjct: 204  TTTVSTT-------GSETTTASTAHSETTAASTMGSETTKVS------------TAGSET 244

Query: 846  SHYLMRKSTIAAVAEVSPFSTMLEVTDESAQRVTASVTVSSFPDIEKLSTPLDNKTATTE 905
            +       T AA  E S  +T      E ++  TAS T   F      +T  +   A+T 
Sbjct: 245  TVSTAGSETTAASTEDSETNTAF---TEDSKTTTASTT--GFETTAASTTGSEPTMASTM 299

Query: 906  VRESWLLTKLVKTTPR--SSYNEMTEMFNFNHTYVAHWT--SETSEGISAGSPTSGSTHI 961
              E+ + + +   T +  ++ +E+T +F      +   T  SET+   + GS T+ +  I
Sbjct: 300  GSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETT-TASI 358

Query: 962  FGEPLGASTTRISETSFSTTPTDRTATSLSDGILPPQPTAAHSSATPVPVTHMFSLPVNG 1021
             G      +T  SET+ ++T    T T+ ++G          S AT V  T   +  V  
Sbjct: 359  MGSETSTDSTTGSETTTASTEGSETTTASTEG----------SEATTVSTTGSETTTV-- 406

Query: 1022 SSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVPPLDQTASTTIVIVPTH 1081
             S+   ET  T +E S +  A ST+V       ++T  T      +  T+ +      T 
Sbjct: 407  -SITDSETTTTCTEGSEMT-AVSTTVFE-----TTTASTEGSEITIASTSDSETTTASTE 459

Query: 1082 GDLIRTTSEATVISVRKTSMAVPSLTETPFHS-LRLSTPVTAKAETTLFS-----TSVDT 1135
            G    TT+  T  S  KT+    S T T  ++ L  +T  T  ++TT  S     T+  +
Sbjct: 460  GS--ETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVS 517

Query: 1136 VTPSTHTLVCSKPPPDNI--PPASSTHVISTT---STPEATQPISQVEETSTYALSFPYT 1190
             T S  T V ++   +       S T  +STT   +T  +T+       ++T A +   +
Sbjct: 518  ATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDS 577

Query: 1191 FSGGGVVASLATG--TTETSVVDETTPSHISANKLTTSVNS----HISSSATYRVHTPVS 1244
              G G  A+   G  TT  S  D    +  +A+  TTS ++      ++S T    T  S
Sbjct: 578  TEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTAS 637

Query: 1245 IQLVTSTSVLSSDKDQMTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGF--- 1301
             +   +T+V ++D +   +S   + RT+  TE S +     + S  T S E + T     
Sbjct: 638  TEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSI 697

Query: 1302 --PETTKISSHQTHSP------SEIPLGTPSDGNLASSPTSGSTQITPT-----LTSSNT 1348
               ETTK+S+  + +       SEI   + +     ++ T GS   T +      TS++T
Sbjct: 698  TGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSAST 757

Query: 1349 VGVHIPEMSTSLGKTALPSQALTITTFLCPEKESTSALPAYTPRTVEMIVNSTYVTHSVS 1408
             G      ST+  +T + S   + TT        T+ +   + +   +   ++  T + +
Sbjct: 758  TGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 817

Query: 1409 YGQDTSFV---------------DTTTSSSTRISNPMDINTTFSHLHSLRTQPEVTSVAS 1453
               +T+ V               +TTT++ST  S     +T  S   +  T+   T+ A+
Sbjct: 818  TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT 877

Query: 1454 FISESTQTF----PESLSLSTAGLYNDGFTVLSDRITTAFSVPNVPTMLPRESSMATSTP 1509
             I   T T      E+ + ST G      +     ITT  +  +  T    E S  T+  
Sbjct: 878  TIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 937

Query: 1510 IYQMSSLPVNVTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTATSGPMSEMSSIPVNN 1569
                    V+ T   +  VS        + S+T     + S  T  S   SE +++    
Sbjct: 938  TEGSELTTVSTTGSETITVS-------AEGSETTTVTTMGSETTTASTAGSETTTVSTAG 990

Query: 1570 SAFTPATVSSDTSTRV---GLFSTLLSSVTPRTTMTMQTSTLDVTPVIYAGATSKNKMVS 1626
            S  T A++    +T V   G  +T +S+    TT+T  T   + T V  AG+ +     +
Sbjct: 991  SETTTASIEGSETTTVSSTGSETTTVSTTGTETTIT-STEGSETTTVTTAGSETTAVYTT 1049

Query: 1627 SAFTTEMIEAPSRITPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSPLSSKSTG 1686
             + TT      S  T T   + +E T      + TT ++   T   GTT  S   S++T 
Sbjct: 1050 GSETTTTSTEGSE-TTTVSTTGSETTTASTADLETTTVS---TSGSGTTTASTAGSETTT 1105

Query: 1687 AISSIPKTTFSPFLSATQQSSQADEATTLGILSGITNRSLSTVNSGTGV--ALTDTYSRI 1744
               +  KTT +        S++  EATT+   S  T  + +T +  T V   +++T +  
Sbjct: 1106 VYITGSKTTTA--------STEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVS 1157

Query: 1745 TVPENMLSPTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLLEK 1804
            T+     + + A S  T+ + + S + T+  + S  T    T +   S  T   TS  E 
Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETT----TASTAGSETTTASTSGSET 1213

Query: 1805 TSLTNYATSLNTPVSYPPWT------------PSSATL-PSLTSFVYSPHSTEAEISTPK 1851
             +     +  +TP S    T             S+A+L P+ TS   S  +T +  ++  
Sbjct: 1214 NTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGSETTTVSITASGA 1273

Query: 1852 TSPPPTSQMVEFPVLGTRMTSSNTQPLLMTSWNIPTAEGSQFPISTTINV-PTSNEMETE 1910
            T+   T     F +  T+ T  + QP+  T  +     G++   S+++ + P  +   + 
Sbjct: 1274 TAASTTVSSTTFVL--TKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASA 1331

Query: 1911 TLHLVPGPLSTFTASQTGLVSKDVMAMSSIPMSGILPNHGLSENPSLST 1959
              H VPG       + +GL +  + A S+    G+    G +  P+ ST
Sbjct: 1332 ASHTVPG----IVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPTSST 1376



 Score =  167 bits (422), Expect = 2e-40
 Identities = 290/1321 (21%), Positives = 523/1321 (39%), Gaps = 194/1321 (14%)

Query: 953  SPTSGSTHIFGEPLGASTTRISETSFSTTPTDRTATSLSDGILPPQPTAAHSSATPVPVT 1012
            +P +GS        G+ TT I   +  TT    TA++       P PT + ++       
Sbjct: 8    APAAGSNTTTASTTGSETTTILIKASETT----TASTAGSETTTPSPTGSQTTI------ 57

Query: 1013 HMFSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVPPLDQTAS 1072
                + ++GS +    T    SE +T++ A S +  + ++  S TT++TA       + +
Sbjct: 58   ----VSISGSEITT--TSTAGSENTTVSSAGSGTTTASMAG-SETTVSTA------GSET 104

Query: 1073 TTIVIVPTHGDLIR-----------TTSEATVISVR----KTSMAVPSLTETPF--HSLR 1115
            TT+ I  T   ++            T+SE TV S       T   V S T T +   S  
Sbjct: 105  TTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSET 164

Query: 1116 LSTPVTAKAETTLFSTSVDTVTPSTHTLVCSKPPPDNIPPASSTHVISTTSTPEATQPIS 1175
             +   T    TT+F+   +T+TPST                S T  +STT +   T   +
Sbjct: 165  TAASTTGSEMTTVFTAGSETITPST----AGSETTTVSTAGSETTTVSTTGSETTTASTA 220

Query: 1176 QVEETSTYALSFPYTFSGGGVVASLATGTTETSVVDETTPSHISANKLTTSV--NSHISS 1233
              E T+   +    T      V++  + TT ++   ETT +    ++  T+   +S  ++
Sbjct: 221  HSETTAASTMGSETT-----KVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTT 275

Query: 1234 SATYRVHTPVSIQLVTSTSVLSSDKDQMTISLGKTPRTMEVTEMSPSKNSFISYSRGTPS 1293
            ++T    T  +    +  ++ S+   + T++    P T +V+  S    +   ++ G+ +
Sbjct: 276  ASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTV--FAAGSET 333

Query: 1294 LEMTDTGFPETTKISSHQTHSPSEIPLG--TPSDGNLASSPTSGSTQITPTLTSSNTVGV 1351
            +  +  G  ETT +S+  + + +   +G  T +D    S  T+ ST+ + T T+S T G 
Sbjct: 334  IRASTVG-SETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTAS-TEGS 391

Query: 1352 HIPEMSTSLGKTALPSQALTITTFLCPEKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQ 1411
                +ST+  +T   S   + TT  C E    +A+      T          T + + G 
Sbjct: 392  EATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFET----------TTASTEGS 441

Query: 1412 DTSFVDTTTSSSTRISNPMDINTTFSHLHSLRTQPEVTSVASFISESTQTFPESLSLSTA 1471
            + +   T+ S +T  S      TT            VT+  S    +  T  E+ + S  
Sbjct: 442  EITIASTSDSETTTASTEGSETTT------------VTTAGSETKTAYTTGSETTTASNT 489

Query: 1472 GLYNDGFTVLSDRITTAFSVPNVPTMLPRESSMATSTPIYQMSSLPVNVTAFTSKKVSDT 1531
            GL            TT F++ +  T    E S  T+     +S+    +T  +++   +T
Sbjct: 490  GL----------ETTTVFTIGSDTTTASTEGSETTA-----VSATGSEMTTVSTEGSENT 534

Query: 1532 PPIVITKSSKTMHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPATVSSDTSTRVGLFSTL 1591
                    + T+    L++  T+T G  SEM+++    +  T  +     +T      + 
Sbjct: 535  TVSTTGSETTTVSTTGLETTTTSTEG--SEMTTVSTTGAETTTDSTEGSGTTAASTAGSE 592

Query: 1592 LSSVTPRTTMTMQTSTLDVTPVIYAGATSKNKMVSSAFTTEMIEAPSRITPTTFLSPTEP 1651
             ++V+   +     ST D +    A  T      +S  ++E   A +  + TT +S T+ 
Sbjct: 593  TTTVSTADSENTTASTAD-SETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDS 651

Query: 1652 TLPFVKTVPTTIMAGIVTPFVGTTAFSPLSSKSTGAISSIPKTTFSPFLSATQQSSQADE 1711
                             T  V TT     S ++  +      TT S   S T  S++   
Sbjct: 652  E----------------TTMVSTTG----SERTITSTEGSETTTVSATGSETTVSTEGSG 691

Query: 1712 ATTLGILSGITNRSLSTVNSGTGVALTD----TYSRITVPENMLSPTHADSLHTSFNIQV 1767
             TT+ I    T + +ST  S T    T+    T + IT  E   + T      T+     
Sbjct: 692  TTTVSITGSETTK-VSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA----- 745

Query: 1768 SPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLL-EKTSLTNYATSLNTPVSYPPWTPS 1826
              S    ++ S  T   +TTT   +S+   M S++  +T++ +   S  T VS       
Sbjct: 746  --STEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVS------- 796

Query: 1827 SATLPSLTSFVYSPHSTEAEISTPKTSPPPTSQMVEFPVLGTRMTSSNTQPLLMTSWNIP 1886
            +A+    T F  +  +T A  +  +T+   T+     P       ++ T     +     
Sbjct: 797  TASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTA 856

Query: 1887 TAEGSQFPISTTINVPTSNEMETETLHLVPGPLSTFTASQTGLVSKDVMAMSSIPMSGIL 1946
            + EGS+    TT     S+E  T T        ++   S+T   S +    ++    G  
Sbjct: 857  STEGSE----TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEG-- 910

Query: 1947 PNHGLSENPSLSTSLRAITSTLADVKHTFEKMTTSVTPGTTLPSILSGATSGSVISKSPI 2006
                 SE  ++ST+    T+   +   T    TT+ T G+ L ++ +  +    +S    
Sbjct: 911  -----SEITTVSTTGSETTTASTEGSET----TTASTEGSELTTVSTTGSETITVSAEGS 961

Query: 2007 LTWLLSSLPS--------GSPPATVSNAPHVMTSSTVEVSKSTFLTSDMISAHPFTNLTT 2058
             T  ++++ S        GS   TVS A    T++++E S++T ++S           T 
Sbjct: 962  ETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSS-----------TG 1010

Query: 2059 LPSATMSTILTRTIPTPTLGGITTGFPTSLPMSINVTDDIVYISTHPEASSRTTITANPR 2118
              + T+ST  T T  T T G  TT   T+       ++     +T  E ++ +T  +   
Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTA------GSETTAVYTTGSETTTTSTEGSETT 1064

Query: 2119 TVSHPSSFSRKTMSPSTTDHTLSVGAMPLPSSTITSSWNRIPTASSPSTLIIPKPTLDSL 2178
            TVS   S   +T + ST D         L ++T+++S +   TAS+  +    + T   +
Sbjct: 1065 TVSTTGS---ETTTASTAD---------LETTTVSTSGSGTTTASTAGS----ETTTVYI 1108

Query: 2179 LNIMTTTSTVPGASFPLISTGVTYPFTA-TVSSPISSFFETTWLDSTPSFLSTEASTSPT 2237
                TTT++  G+    +ST  +   TA T  S +++ F T    +T S + +EA+TS  
Sbjct: 1109 TGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSA 1168

Query: 2238 A 2238
            A
Sbjct: 1169 A 1169



 Score =  164 bits (415), Expect = 1e-39
 Identities = 327/1450 (22%), Positives = 566/1450 (39%), Gaps = 155/1450 (10%)

Query: 852  KSTIAAVAEVSPFSTMLEVTDESAQRVTASVTVSSFPDIEKLSTPLDNKTATTEVRESWL 911
            ++T+A  A  +  +     ++ +   + AS T ++     + +TP    + TT V  S  
Sbjct: 4    ETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISG- 62

Query: 912  LTKLVKTTPRSSYNEMTEMFNFNHTYVAHWTSETSEGISAGSPTS-----GSTHIFGEPL 966
             +++  T+   S N          T  +   SET+   +AGS T+     G+       +
Sbjct: 63   -SEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVS-TAGSETTTVSITGTETTMVSAM 120

Query: 967  GASTTRISETSFSTTPTD----RTATSLSDGILPPQPTAAHSSATPVPVT--HMFSLPVN 1020
            G+ TT  S TS  TT T      T T  + G        A S  T    T   M ++   
Sbjct: 121  GSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180

Query: 1021 GSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVPPLDQTASTTIVIVPT 1080
            GS  +   T    SE +T++ A S +     +   +TT +TA     + TA++T+    T
Sbjct: 181  GSETITPST--AGSETTTVSTAGSETTTVSTTGSETTTASTA---HSETTAASTMGSETT 235

Query: 1081 HGDLIRTTSEATVISVRKTSMAVPSLTETPFHSLRLSTPVTAKAETTLFSTSVDTVTPST 1140
                + T    T +S   +     S  ++  ++       T  A TT F T+  + T S 
Sbjct: 236  K---VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSE 292

Query: 1141 HTLVCSKPPPDNIPPASSTHVISTTSTPEATQPISQVEETSTYALSFPYTFSGGGVVASL 1200
             T+  +           S   +++T  PE T+  +   E +T        F+ G      
Sbjct: 293  PTMASTM---------GSETTMASTIGPETTKVSTASSEVTT-------VFAAGSETIRA 336

Query: 1201 ATGTTETSVVD----ETTPSHISANKLTT--SVNSHISSSATYRVHTPV-SIQLVTSTSV 1253
            +T  +ET+ V     ETT + I  ++ +T  +  S  ++++T    T   S +   +T+V
Sbjct: 337  STVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTV 396

Query: 1254 LSSDKDQMTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTH 1313
             ++  +  T+S+  +  T   TE             G+    ++ T F ETT  S+    
Sbjct: 397  STTGSETTTVSITDSETTTTCTE-------------GSEMTAVSTTVF-ETTTASTEG-- 440

Query: 1314 SPSEIPLGTPSDGNLASSPTSGSTQITPTLTSSNTVGVHIP-EMSTSLGKTALPSQAL-- 1370
              SEI + + SD    ++ T GS   T T   S T   +     +T+   T L +  +  
Sbjct: 441  --SEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFT 498

Query: 1371 --TITTFLCPEKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTT----TSSST 1424
              + TT    E   T+A+ A       +    +  T   + G +T+ V TT    T++ST
Sbjct: 499  IGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTST 558

Query: 1425 RISNPMDINTTFSHLHSLRTQPEVTSVASFISESTQTFP----ESLSLSTAGLYNDGFTV 1480
              S    ++TT +   +  T+   T+ AS     T T      E+ + STA       + 
Sbjct: 559  EGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSAST 618

Query: 1481 LSDRITTAFSVPNVPTMLPRESSMATSTPIYQMSSLPVNVTA----FTSKKVSDTPPI-- 1534
                 TTA +  +  T    E S  T+       +  V+ T      TS + S+T  +  
Sbjct: 619  TGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSA 678

Query: 1535 ------VITKSSKTMHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPATVSSDTSTRVGLF 1588
                  V T+ S T       S  T  S   SE ++     S  T A+++   +T     
Sbjct: 679  TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTA--- 735

Query: 1589 STLLSSVTPRTTMTMQTSTLDVT--PVIYAGATSKNKMVSSAFTTEMIEAPSRITPTTFL 1646
            ST  S  T  +T   +T++   T      A  TS    ++S   +E   A +  + TT +
Sbjct: 736  STEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKV 795

Query: 1647 SPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSPLSSKSTGAISSIPKTTF---------- 1696
            S     +       TT+        + +T  S  ++ ST    +IP +T           
Sbjct: 796  STASSKM-------TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTST 848

Query: 1697 ------------SPFLSATQQSSQADEATTLG------ILSGITNRSLSTVNSGTGVALT 1738
                        S   +A+ +SS+   ATT+G         G    + ST  S T  A T
Sbjct: 849  EGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAST 908

Query: 1739 DTYSRITVPENMLSPTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKM 1798
            +  S IT      S T   S   S     S   +   + S  T +   T +   S T  +
Sbjct: 909  EG-SEITTVSTTGSETTTASTEGSETTTASTEGSELTTVS-TTGSETITVSAEGSETTTV 966

Query: 1799 TSLLEKTSLTNYATSLNTPVSYPPWTPSSATLP-SLTSFVYSPHSTEAEISTPKTSPPPT 1857
            T++  +T+  + A S  T VS      ++A++  S T+ V S  S    +ST  T    T
Sbjct: 967  TTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTIT 1026

Query: 1858 SQMVEFPVLGTRMTSSNTQPLLMTSWNIPTAEGSQFPISTTINVPTSNEMETETLHLVPG 1917
            S   E     T  T+ +    + T+ +  T   ++   +TT++   S      T  L   
Sbjct: 1027 S--TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT 1084

Query: 1918 PLSTFTASQTGLVSKDVMAMSSIPMSGILPNHGLSENPSLSTSLRAITSTLADVKHTFEK 1977
             +ST + S T   S      +++ ++G       +E  S +T++   +S       T  +
Sbjct: 1085 TVST-SGSGTTTASTAGSETTTVYITGSKTTTASTEG-SEATTVSTTSSETTTASTTGSE 1142

Query: 1978 MT---TSVTPGTTLPSILSGATSGSVISKSPILTWLLSSLPSGSPPATVSNAPHVMTSST 2034
            MT   T+V+  TT+ +I S AT+ S        T        GS   T S A    T+++
Sbjct: 1143 MTTVFTTVSETTTVSTIGSEATTSSAAGSEATTT-----STEGSETTTASTAGSETTTAS 1197

Query: 2035 VEVSKSTFLT---SDMISAHPFTNLTTLPSATMSTILTRTI--PTPTLGGITTGFPTSLP 2089
               S++T  +   S+  +A    + T+ PS+  S   T  I     T+    +  PT+  
Sbjct: 1198 TAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATS 1257

Query: 2090 MSINVTDDIVYISTHPEASSRTTITANPRTVSHPSSFSRKTMSPSTTDHTLSVGAMPLPS 2149
            ++ + T  +   ++   A+S TT+++    ++  +  S + ++ +    T + G     S
Sbjct: 1258 LTGSETTTVSITASGATAAS-TTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTAS 1316

Query: 2150 STITSSWNRIPTASSPSTLIIPKPTLDSLLNIMTTTSTVPGASFPLISTGVTYPFTATVS 2209
            S++T +     TAS+ S  +   P +  +LN     ++  GAS    + GV    T +  
Sbjct: 1317 SSVTMAPGMDFTASAASHTV---PGI--VLNTSGLGTSTMGASSTTSAHGVR-TTTGSTR 1370

Query: 2210 SPISSFFETT 2219
             P SS F+ T
Sbjct: 1371 EPTSSTFQET 1380



 Score =  147 bits (371), Expect = 2e-34
 Identities = 265/1153 (22%), Positives = 443/1153 (38%), Gaps = 135/1153 (11%)

Query: 1204 TTETSVVDETTPSHISANKLTTSVNSHISS---SATYRVHTPVSIQLVTSTSVLSSDKDQ 1260
            TT ++   ETT   I A++ TT+  +   +   S T    T VSI     T+  ++  + 
Sbjct: 16   TTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSEN 75

Query: 1261 MTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSPSEIPL 1320
             T+S   +  T     M+ S+ +  +    T ++ +T T   ETT +S+          +
Sbjct: 76   TTVSSAGSGTT--TASMAGSETTVSTAGSETTTVSITGT---ETTMVSA----------M 120

Query: 1321 GTPSDGNLASSPTSGSTQITPTLTSSNTVGVHIPEMSTSLGKTALPSQALTITTFLCPEK 1380
            G+ +  N   S TS  T +T T  S  T       +ST   +T         TT    + 
Sbjct: 121  GSETTTN---STTSSETTVTSTAGSETTT------VSTVGSET---------TTAYTADS 162

Query: 1381 ESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINTTFSHLH 1440
            E+T+A    +  T      S  +T S + G +T+ V T  S +T +S      TT S  H
Sbjct: 163  ETTAASTTGSEMTTVFTAGSETITPSTA-GSETTTVSTAGSETTTVSTTGSETTTASTAH 221

Query: 1441 SLRTQPEVTSVASFISESTQ--TFPESLSLSTAGLYNDGFTVLSDRITTAFSVPNVPTML 1498
            S     E T+ ++  SE+T+  T     ++STAG      +       TAF+        
Sbjct: 222  S-----ETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFT-------- 268

Query: 1499 PRESSMATSTPIYQMSSLPVNVTAFTSKKVSDT---PPIVITKSSKTMHPGCLKSPCTAT 1555
              E S  T+           + T F +   S T   P +  T  S+T     +    T  
Sbjct: 269  --EDSKTTTA----------STTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKV 316

Query: 1556 SGPMSEMSSI-PVNNSAFTPATVSSDTSTRVGLFSTLLSSVTPRTTMTMQTSTLDVTPVI 1614
            S   SE++++    +     +TV S+T+T     ST  S  T  + M  +TST   T   
Sbjct: 317  STASSEVTTVFAAGSETIRASTVGSETTT----VSTTGSETTTASIMGSETSTDSTT--- 369

Query: 1615 YAGATSKNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGT 1674
                T+      S  TT   E     T +T  S T           TT   G     V T
Sbjct: 370  -GSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVST 428

Query: 1675 TAFSPLSSKSTGAISSIPKTTFSPFLSATQQSSQADEATTLG--ILSGITNRSLSTVNSG 1732
            T F   ++ + G+  +I  T+ S   +A+ + S+    TT G    +  T  S +T  S 
Sbjct: 429  TVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASN 488

Query: 1733 TGVALTDTYSRITVPENMLSPTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFS 1792
            TG+  T  ++       + S T   S   S    VS + +   + S       T +   S
Sbjct: 489  TGLETTTVFT-------IGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGS 541

Query: 1793 SNTRKMTSLLEKTSLTNYATSLNTPVSYPPWTPSSATLPSLTSFVYSPHSTEAEISTPKT 1852
              T   T+ LE T+ +   + + T  +    T + +T  S T+   +  S    +ST   
Sbjct: 542  ETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTAD- 600

Query: 1853 SPPPTSQMVEFPVLGTRMTSSNTQPLLMTSWNIPTA--EGSQFPISTTINVPTSNEMETE 1910
            S   T+   +        T S T     TS    TA  EGS+    +T +  T+    T 
Sbjct: 601  SENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTG 660

Query: 1911 TLHLVPGP--LSTFTASQTG---LVSKDVMAMSSIPMSGILPNHGLSENPSLSTSLRAIT 1965
            +   +       T T S TG    VS +    +++ ++G       SE   +ST+    T
Sbjct: 661  SERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITG-------SETTKVSTTGSETT 713

Query: 1966 ST------LADVKHTFEKMTTSVTPGTTLPSILSGATSGSVISKSPILTWLLSSLPSGSP 2019
            +T      +     T  + TT+ T G+   +  +  +  +  S +   T   S+  S + 
Sbjct: 714  TTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETT 773

Query: 2020 PATVSNAPHVMTSST-VEVSKSTFLTSDMISAHPFTNLTTLPSAT------MSTILTRTI 2072
             A++  +   M S+   E +K +  +S M +     + TT+ S T      +ST  + TI
Sbjct: 774  MASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETI 833

Query: 2073 PTPTLGGITTGFPTSLPMSINVTDDIVYISTHPEASSRTTITANPRTVSHPSSFSRKTMS 2132
            P  T G  TT        +   T+     +   E S  TT +      +  ++   +T +
Sbjct: 834  PASTAGSETT--------TTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTT 885

Query: 2133 PSTT-DHTLSVGAMPLPSSTITSSWNRIPTASSPSTLIIPKPTLDSLLNIMTTTSTVPGA 2191
             ST    T +       ++T ++  + I T S+  +    + T  S     TTT++  G+
Sbjct: 886  ASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGS----ETTTASTEGSETTTASTEGS 941

Query: 2192 SFPLISTGVTYPFTATVSSPISSFFETTWLDSTPSFLSTEASTSPTATK--STVSFYNVE 2249
                +ST  T   T TVS+  S     T + S  +  ST  S + T +   S  +  ++E
Sbjct: 942  ELTTVST--TGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIE 999

Query: 2250 MSFSVFVEEPRIPITSVINEFTENSLNSIFQNSEFSLATLETQIKSRDISEEEMVMDRAI 2309
             S +  V       T+V    TE ++ S   +   ++ T  ++  +   +  E       
Sbjct: 1000 GSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSE-----TT 1054

Query: 2310 LEQREGQEMATIS 2322
                EG E  T+S
Sbjct: 1055 TTSTEGSETTTVS 1067



 Score =  145 bits (367), Expect = 5e-34
 Identities = 274/1150 (23%), Positives = 454/1150 (39%), Gaps = 122/1150 (10%)

Query: 1154 PPASSTHVISTTSTPEATQPISQVEETSTYALSFPYTFSGGGVVASLATGTTETSVVDET 1213
            P A S    ++T+  E T  + +  ET+T + +   T             TT +    +T
Sbjct: 9    PAAGSNTTTASTTGSETTTILIKASETTTASTAGSET-------------TTPSPTGSQT 55

Query: 1214 TPSHISANKLTT-----SVNSHISSSATYRVHTPVSIQLVTSTSVLSSDKDQMTISLGKT 1268
            T   IS +++TT     S N+ +SS+ +    T  +    + T+V ++  +  T+S+  T
Sbjct: 56   TIVSISGSEITTTSTAGSENTTVSSAGS---GTTTASMAGSETTVSTAGSETTTVSITGT 112

Query: 1269 PRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSP------SEIPLGT 1322
              TM     S +  +  + S  T    +T T   ETT +S+  + +       SE    +
Sbjct: 113  ETTMVSAMGSETTTNSTTSSETT----VTSTAGSETTTVSTVGSETTTAYTADSETTAAS 168

Query: 1323 PSDGNLASSPTSGSTQITPTLTSS-----NTVGVHIPEMSTSLGKTALPSQALTITTFLC 1377
             +   + +  T+GS  ITP+   S     +T G     +ST+  +T   S A + TT   
Sbjct: 169  TTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAAS 228

Query: 1378 PE-KESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDT------------TTSSST 1424
                E+T    A +  TV    + T    +     +T+F +             TT++ST
Sbjct: 229  TMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST 288

Query: 1425 RISNPMDINTTFSHLHSLRT-QPEVTSVASFISESTQTFP---ESLSLSTAGLYNDGFTV 1480
              S P   +T  S      T  PE T V++  SE T  F    E++  ST G      + 
Sbjct: 289  TGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVST 348

Query: 1481 LSDRITTAFSVPNVPTMLPRESSMATSTPIYQMSSLPVNVTAFTSKKVSDTPPIVITKSS 1540
                 TTA S+    T     +   T+T   + S      TA T    + T   V T  S
Sbjct: 349  TGSETTTA-SIMGSETSTDSTTGSETTTASTEGSE---TTTASTEGSEATT---VSTTGS 401

Query: 1541 KTMHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPATVSSDTSTRVGLFSTLLSSVTPRTT 1600
            +T       S  T T    SEM++  V+ + F   T S++ S         ++S +   T
Sbjct: 402  ETTTVSITDSETTTTCTEGSEMTA--VSTTVFETTTASTEGS------EITIASTSDSET 453

Query: 1601 MTMQTSTLDVTPVIYAGATSKNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTLPFVKTVP 1660
             T  T   + T V  AG+ +K    + + TT         T T F   ++ T    +   
Sbjct: 454  TTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT-TVFTIGSDTTTASTEGSE 512

Query: 1661 TTIMAGIVTPFVGTTAFSPLSSKSTGAISSIPKTTFSPF-LSATQQSSQADEATTLGILS 1719
            TT ++   +    TT  +  S  +T + +    TT S   L  T  S++  E TT+   +
Sbjct: 513  TTAVSATGSEM--TTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVST-T 569

Query: 1720 GITNRSLSTVNSGTGVALTDTYSRITVP----ENMLSPTHADSLHTSFNIQVSP----SL 1771
            G    + ST  SGT  A T      TV     EN  + T ADS  TS +   S     S 
Sbjct: 570  GAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAST-ADSETTSASTTGSETTTAST 628

Query: 1772 TSFKSASGPTKNVKTTT-NCFSSNTRKMTSLLEKTSLTNYATSLNTPVSYPPWTPSSATL 1830
            TS ++ +  T+  +TTT +   S T  +++   + ++T+   S  T VS      + +T 
Sbjct: 629  TSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTE 688

Query: 1831 PSLTSFVYSPHSTEAEISTPKTSPPPTS----QMVEFPVLGTRMTSSNTQPLLMTSWNIP 1886
             S T+ V    S   ++ST  +    TS    ++    + G+  T+++T+    T+    
Sbjct: 689  GSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT---A 745

Query: 1887 TAEGSQFPISTTINVPTSNEMETETLHLVPGPLSTFTASQTGLVSKDVMAMSSIPMSGIL 1946
            + EGS+    TT    T +E  T +       +++   S+T + S      + +  +   
Sbjct: 746  STEGSE----TTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSK 801

Query: 1947 PNHGLSENPSLSTSLRAITSTLADVKHTFEKMTTSVTPGTTLPSILSGATSGSVISKSPI 2006
                 +EN     S   I ST A      E  T S     T+P+  +G+ + +  S    
Sbjct: 802  MTTVFTEN-----SETTIASTTAS-----ETTTVSTAGSETIPASTAGSETTTTTSTEGS 851

Query: 2007 LTWLLSSLPSGSPPATVSNAPHVMTSSTVEVSKSTFLT---SDMISAHPFTNLTTLPSA- 2062
             T   S+   GS   T S      T++T   S++T  +   S+  +     + TT  S  
Sbjct: 852  ETTTAST--EGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTE 909

Query: 2063 -----TMSTILTRTIPTPTLGGITTGFPTSLPMSINV-TDDIVYISTHPEASSRTTITAN 2116
                 T+ST  + T    T G  TT   T       V T     I+   E S  TT+T  
Sbjct: 910  GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTM 969

Query: 2117 PRTVSHPSSFSRKTMSPSTT-DHTLSVGAMPLPSSTITSSWNRIPTASSPSTLIIPKPTL 2175
                +  S+   +T + ST    T +       ++T++S+ +   T S+  T    + T+
Sbjct: 970  GSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGT----ETTI 1025

Query: 2176 DSLLNIMTTTSTVPGASFPLI-STGVTYPFTATVSSPISSFFETTWLDSTPSFLSTEAST 2234
             S     TTT T  G+    + +TG     T+T  S  ++   T    +T S    E +T
Sbjct: 1026 TSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTT 1085

Query: 2235 SPTATKSTVS 2244
              T+   T +
Sbjct: 1086 VSTSGSGTTT 1095



 Score = 88.6 bits (218), Expect = 9e-17
 Identities = 148/643 (23%), Positives = 236/643 (36%), Gaps = 78/643 (12%)

Query: 219  IPTVDRTLRCFVPENMTIQEKSTTVSQQIDMTTPSQITGVKPQNTAHSSTLLSQSIPIFA 278
            + T    +     EN      STT S+   ++T    T   P +TA S T  + S     
Sbjct: 795  VSTASSKMTTVFTENSETTIASTTASETTTVSTAGSET--IPASTAGSETTTTTSTEGSE 852

Query: 279  TDYTTISYSNTTSPPL---ETMTAQKI------LKTLVDETATFAVDVLSTSSAISLPTQ 329
            T   +   S TT+      ET TA  I        T   ET T + +   T++A    T+
Sbjct: 853  TTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTA---STE 909

Query: 330  SISIDNTTNSMKKTKSPSSESTKTTKMVEAMATEIFQPPTPSNFLSTSRFTKNSVVSTTS 389
               I   + +  +T + S+E ++TT      +TE  +  T S        T  S   T S
Sbjct: 910  GSEITTVSTTGSETTTASTEGSETT----TASTEGSELTTVS--------TTGSETITVS 957

Query: 390  AIKSQSAVTKTTSLFSTIESTSMSTTPCLKQKSTNTGALPISTAGQEFIESTAAGTVPWF 449
            A  S++    T    +T  ST+ S T              +STAG E   ++  G+    
Sbjct: 958  AEGSETTTVTTMGSETTTASTAGSET------------TTVSTAGSETTTASIEGS-ETT 1004

Query: 450  TVEKTSPASTHVGTASSFPPEPVLISTAAPVDSVFPRNQTAFPLATTDMKIAFTVHSLTL 509
            TV  T   +T V T            T   + S      T    A ++    +T  S T 
Sbjct: 1005 TVSSTGSETTTVSTT----------GTETTITSTEGSETTTVTTAGSETTAVYTTGSET- 1053

Query: 510  PTRLIETTPAPRTAETELTSTNFQDVSLPRVEDAMSTSMSKETSSKTFSFLTSFSFTGTE 569
                  TT +   +ET   ST   + +     D  +T++S   S       T+ S  G+E
Sbjct: 1054 ------TTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG-----TTTASTAGSE 1102

Query: 570  SVQTVIDAEATRTALTPEITLASTVAETMLSSTITGRVYTQNTPTADGHLLTLMSTRSAS 629
            +    I    T TA T E + A+TV+ T   +T         T +  G  +T + T  + 
Sbjct: 1103 TTTVYITGSKTTTAST-EGSEATTVSTTSSETT---------TASTTGSEMTTVFTTVSE 1152

Query: 630  TSKAPESGPTSTTDEAAHLFSSNETIWTSRPDQALLASMNTTTILTFVPNENFTSAFHEN 689
            T+     G  +TT  AA   ++  +   S    A  A   TTT  T   +E  T++   +
Sbjct: 1153 TTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAST-AGSETTTASTSGS 1211

Query: 690  TTYTEYLSATTNITPLKASPEGK-----GTTANDATTARYTTAVSKLTSPWFANFSIVSG 744
             T T   + +   TP  A  E       G+ +  A+TA      + LT       SI + 
Sbjct: 1212 ETNTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGSETTTVSITAS 1271

Query: 745  TTSITNMPEFKLTTLLLKTIPMSTKPANELPLTPRETVVPSVDIISTLACIQPNFSTEES 804
              +  +      T +L K   +S +P    P++   T    +   S++        T  +
Sbjct: 1272 GATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASA 1331

Query: 805  ASETTQTEINGAIVFGGTTTPVPKSATTQRLNATV-TRKEATS 846
            AS T    +      G +T     + +   +  T  + +E TS
Sbjct: 1332 ASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPTS 1374


>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
            sapiens]
          Length = 1521

 Score =  201 bits (511), Expect = 9e-51
 Identities = 351/1539 (22%), Positives = 586/1539 (38%), Gaps = 175/1539 (11%)

Query: 343  TKSPSSESTKTTKMVEAMATEIFQP-------PTPSNFLSTSRFTKNSVVSTTSAIKSQS 395
            T + ++ S  TT +++A  T            P+P+   +T      S ++TTS   S++
Sbjct: 16   TTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSEN 75

Query: 396  AVTKTTSLFSTIESTSMSTTPCLKQKSTNTGALPISTAGQEFIESTAAGTVPWFTVEKTS 455
                     +T+ S    TT      S  T    +STAG E    +  GT         S
Sbjct: 76   ---------TTVSSAGSGTTTASMAGSETT----VSTAGSETTTVSITGTETTMVSAMGS 122

Query: 456  PASTHVGTASSFPPEPVLISTAAPVDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIE 515
              +T+  T+S         S    V +V     TA+   +     + T   +T       
Sbjct: 123  ETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGS 182

Query: 516  TTPAPRTAETELTSTNFQDVSLPRVEDAMSTSMSKETSSKTFSFLTSFSFTGTESVQ-TV 574
             T  P TA +E T+ +        V    +T     T+S   S  T+ S  G+E+ + + 
Sbjct: 183  ETITPSTAGSETTTVSTAGSETTTVS---TTGSETTTASTAHSETTAASTMGSETTKVST 239

Query: 575  IDAEATRTALTPEITLASTV-AETMLSSTITGRVYTQNT-------PTADGHLLTLMSTR 626
              +E T +    E T AST  +ET  + T   +  T +T        +  G   T+ ST 
Sbjct: 240  AGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTM 299

Query: 627  SASTSKAPESGPTSTTDEAAHLFSSNETIWTSRPDQALLASM--NTTTILTFVPNENFTS 684
             + T+ A   GP +T    A   SS  T   +   + + AS   + TT ++   +E  T+
Sbjct: 300  GSETTMASTIGPETTKVSTA---SSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTA 356

Query: 685  AFHENTTYTEYLSATTNITPLKASPEGKGTTANDATTARYTTAVSKLTSPWFANFSIVSG 744
            +   + T T+   +TT      AS EG  TT      +  TT             S    
Sbjct: 357  SIMGSETSTD---STTGSETTTASTEGSETTTASTEGSEATTV------------STTGS 401

Query: 745  TTSITNMPEFKLTTLLLKTIPMSTKPANELPLTPRETVVPSVDIISTLACIQPNFSTEES 804
             T+  ++ + + TT   +   M+         T   T    + I ST        STE S
Sbjct: 402  ETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGS 461

Query: 805  ASETTQTEINGAIVFGGTTTPVPKSATTQRLNATVTRKEATSHYLMRKSTIAAVAEVSPF 864
             + T  T         G+ T    +  ++   A+ T  E T+ + +   T  A  E S  
Sbjct: 462  ETTTVTT--------AGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 513

Query: 865  -------STMLEVTDESAQRVTASVTVSSFPDIEKLSTPLDNKTATTEVRESWLLTKLVK 917
                   S M  V+ E ++  T S T S    +   +T L+  T +TE  E       V 
Sbjct: 514  TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVS--TTGLETTTTSTEGSE----MTTVS 567

Query: 918  TTPRSSYNEMTEMFNFNHTYVAHWTSETSEGISAGSPTSGSTHIFGEPLGASTTRISETS 977
            TT   +  + TE      T  +   SET+   +A S  + ++    E   ASTT  SET+
Sbjct: 568  TTGAETTTDSTE--GSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTG-SETT 624

Query: 978  FSTTPTDRTATSLSDGILPPQPTAAHSSATPVPVTHMFSLPVNGSSVVAEETEVTMSEPS 1037
             ++T +  T T+ ++G          S  T V  T               ++E TM   +
Sbjct: 625  TASTTSSETTTASTEG----------SETTTVSTT---------------DSETTMVSTT 659

Query: 1038 TLARAFSTSVLSDVSNLSSTTMTTALVPPLDQTASTTIVIVPTHGDLIRTT-SEATVISV 1096
               R  +++  S+ + +S+T   T +    + + +TT+ I  +    + TT SE T+ S 
Sbjct: 660  GSERTITSTEGSETTTVSATGSETTV--STEGSGTTTVSITGSETTKVSTTGSETTITST 717

Query: 1097 RKTSMAVPSLTETPFHSLRLSTPVTAKAETTLFSTSVDTVTPSTHTLVCSKPPPDNIPPA 1156
              + +   S+T +       +T  T  +ETT  ST   + T S  T              
Sbjct: 718  EGSEITTASITGS-----ETTTASTEGSETTTASTE-GSETTSASTTGSETTTASTTSSE 771

Query: 1157 SSTHVISTTSTPEATQPISQVEETSTYALSFPYTFSGGGVVASLATGTTETSVV----DE 1212
            ++   I  + T  A+   S+  + ST +      F+        +T  +ET+ V     E
Sbjct: 772  TTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831

Query: 1213 TTPSHISANKLTTSVNSHISSSATYRVH----TPVSIQLVTSTSVLSSDKDQMTISLGKT 1268
            T P+  + ++ TT+ ++  S + T        T  S +   +T+  +   +  T S   +
Sbjct: 832  TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS 891

Query: 1269 PRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSPSEIPLGTPSDGNL 1328
              T   TE S +     + + G+    ++ TG  ETT  S+      SE    +     L
Sbjct: 892  ETTTTSTEGSETTT---ASTEGSEITTVSTTG-SETTTAST----EGSETTTASTEGSEL 943

Query: 1329 ASSPTSGSTQITPT-----LTSSNTVGVHIPEMSTSLGKTALPSQALTITTFLCPEKEST 1383
             +  T+GS  IT +      T+  T+G      ST+  +T   S A + TT    E   T
Sbjct: 944  TTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSET 1003

Query: 1384 SALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINTTFSHLHSLR 1443
            + + +    T  +    T  T + + G +T+ V T  S +T +       TT S   S  
Sbjct: 1004 TTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGS-- 1061

Query: 1444 TQPEVTSVASFISESTQTFPESLSLSTAGLYNDGFTVLS---DRITTAFSVPNVPTMLPR 1500
               E T+V++  SE+T      L  +T      G T  S      TT +   +  T    
Sbjct: 1062 ---ETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTAST 1118

Query: 1501 ESSMATSTPIYQMSSLPVNVTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTATSGPMS 1560
            E S AT+      ++     TA T+     T   V T  S+T     + S  T +S   S
Sbjct: 1119 EGSEATTV----STTSSETTTASTTGSEMTT---VFTTVSETTTVSTIGSEATTSSAAGS 1171

Query: 1561 EMSSIPVNNSAFTPA-TVSSDTSTRVGLFSTLLSSVTPRTTMTMQTSTLDVTPVIYAGAT 1619
            E ++     S  T A T  S+T+T     ST  S  T  +T   +T+T   T    +  +
Sbjct: 1172 EATTTSTEGSETTTASTAGSETTTA----STAGSETTTASTSGSETNTACTTGSETSTPS 1227

Query: 1620 SKNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSP 1679
            S     ++AF   +I + + I  T  L PT  +L   +T   +I A       G TA S 
Sbjct: 1228 SAGSETNTAF---IIGSETTIASTASLEPTATSLTGSETTTVSITAS------GATAAST 1278

Query: 1680 LSSKSTGAISSIPKTTFSPFLSATQQSSQADEATTLGILSGITNRSLSTVNSGTGVALTD 1739
              S +T  ++     +  P  +     ++          +G    + S+V    G+  T 
Sbjct: 1279 TVSSTTFVLTKATDVSIQPITNTPMSGTRT---------TGTRLTASSSVTMAPGMDFTA 1329

Query: 1740 TYSRITVPENMLSPTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMT 1799
            + +  TVP  +L   +   L TS     + S TS       T + +  T+     T  ++
Sbjct: 1330 SAASHTVPGIVL---NTSGLGTS--TMGASSTTSAHGVRTTTGSTREPTSSTFQETGPVS 1384

Query: 1800 SLLEKTSLTNYATSLNTPVSY-PPWTPSSATLPSLTSFV 1837
                  S+++  T++  P  Y  PW     +L ++ + V
Sbjct: 1385 MGTNTVSMSHTPTNVIKPSGYLQPWAIILISLAAVVAAV 1423



 Score =  192 bits (488), Expect = 4e-48
 Identities = 355/1506 (23%), Positives = 590/1506 (39%), Gaps = 195/1506 (12%)

Query: 235  TIQEKSTTVSQQIDMTTPSQITGVKPQ-NTAHSSTLLSQSIPIFATDYTTIS-YSNTTSP 292
            T   ++TTVS     TT + + G +   +TA S T    ++ I  T+ T +S   + T+ 
Sbjct: 70   TAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETT---TVSITGTETTMVSAMGSETTT 126

Query: 293  PLETMTAQKILKTLVDETATFAVDVLSTSSAISLPTQSISIDNTTNSM-------KKTKS 345
               T +   +  T   ET T +     T++A +  +++ +   T + M        +T +
Sbjct: 127  NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETIT 186

Query: 346  PSSESTKTTKMVEAMATEIFQPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFS 405
            PS+  ++TT +  A +       T S   +T+  T +S  +  S + S++    T    +
Sbjct: 187  PSTAGSETTTVSTAGSETTTVSTTGSE--TTTASTAHSETTAASTMGSETTKVSTAGSET 244

Query: 406  TIESTSMSTTPCLKQKS-TNTGALPIS---TAGQEFIESTAAGTVPWFTVEKTSPAST-- 459
            T+ +    TT    + S TNT     S   TA     E+TAA T    T  + + AST  
Sbjct: 245  TVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST----TGSEPTMASTMG 300

Query: 460  -HVGTASSFPPEPVLISTAAP-VDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETT 517
                 AS+  PE   +STA+  V +VF         +T   +      + T+ T   ETT
Sbjct: 301  SETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSE------TTTVSTTGSETT 354

Query: 518  PAP-RTAETELTSTNFQDVSLPRVEDAMSTSMSKETSSKTFSFLTSFSFTGTESVQTVID 576
             A    +ET   ST   + +    E + +T+ S E S  T     + S TG+E+    I 
Sbjct: 355  TASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEAT-----TVSTTGSETTTVSIT 409

Query: 577  AEATRTALTP--EITLASTVAETMLSSTITGRVYTQNTPTADGHLLTLMSTRSASTSKAP 634
               T T  T   E+T  ST             V+   T + +G  +T+ ST  + T+ A 
Sbjct: 410  DSETTTTCTEGSEMTAVSTT------------VFETTTASTEGSEITIASTSDSETTTAS 457

Query: 635  ESGPTSTTDEAAHLFSSNETIWT--SRPDQALLASMNTTTILTFVPNENFTSAFHENTTY 692
              G  +TT   A   S  +T +T  S    A    + TTT+ T     + T+A  E +  
Sbjct: 458  TEGSETTTVTTAG--SETKTAYTTGSETTTASNTGLETTTVFTI--GSDTTTASTEGSET 513

Query: 693  TEYLSATTNITPLKASPEGK-----GTTANDATTARYTTAVSKLTSPWFANFSIVS--GT 745
            T   +  + +T +  S EG       TT ++ TT   T   +  TS   +  + VS  G 
Sbjct: 514  TAVSATGSEMTTV--STEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGA 571

Query: 746  TSITNMPEFKLTTLL----LKTIPMSTKPANELPLTPRETVVPSVDIISTLACIQPNFST 801
             + T+  E   TT       +T  +ST  +         T   + D  +T A       +
Sbjct: 572  ETTTDSTEGSGTTAASTAGSETTTVSTADS-------ENTTASTADSETTSA---STTGS 621

Query: 802  EESASETTQTEINGAIVFGGTTTPVPKS-ATTQRLNATVTRKEATSHYLMRKSTIAAVAE 860
            E + + TT +E   A   G  TT V  + + T  ++ T + +  TS      +T++A   
Sbjct: 622  ETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGS 681

Query: 861  VSPFSTMLEVTDESAQRVTASVTVSSFPDIEKLSTPLDNKTATTEVRESWLLTKLV---K 917
             +  ST      E +   T S+T S   +  K+ST   ++T  T    S + T  +   +
Sbjct: 682  ETTVST------EGSGTTTVSITGS---ETTKVST-TGSETTITSTEGSEITTASITGSE 731

Query: 918  TTPRSSYNEMTEMFNFNHTYVAHWTSETSEGISAGSPTS--------GSTHIFGEPLGAS 969
            TT  S+    T   +   +     ++  SE  +A + +S        GS       +G+ 
Sbjct: 732  TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSE 791

Query: 970  TTRISETS--FSTTPTDRTATSLSDGILPPQPTAAHSSATPVPVTHMFSLPVNGSSVVAE 1027
            TT++S  S   +T  T+ + T+++        T + + +  +P +   S     +S    
Sbjct: 792  TTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGS 851

Query: 1028 ETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVPPLDQTASTTIVIVPTHGDLIRT 1087
            ET    +E S    A + S  +  +    +  TTA     + T ++T             
Sbjct: 852  ETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTST------------E 899

Query: 1088 TSEATVISVRKTSMAVPSLT--ETPFHSLRLSTPVTAKAE----TTLFSTSVDTVTPS-- 1139
             SE T  S   + +   S T  ET   S   S   TA  E    TT+ +T  +T+T S  
Sbjct: 900  GSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAE 959

Query: 1140 -THTLVCSKPPPDNIPPASSTHVISTTSTPEATQPISQVEETSTYALSFPYTFSGGGVVA 1198
             + T   +    +    +++    +T ST  +    + +E + T  +S   T S    V+
Sbjct: 960  GSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVS--STGSETTTVS 1017

Query: 1199 SLATGTTETSVVDETTPSHISANKLTTSVNSHISSSATYRVH----TPVSIQLVTSTSVL 1254
            +  T TT TS     T +  +A   TT+V +  S + T        T VS     +T+  
Sbjct: 1018 TTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAS 1077

Query: 1255 SSDKDQMTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHS 1314
            ++D +  T+S   +  T   T  S +   +I+ S+ T +     T   E T +S+     
Sbjct: 1078 TADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTA----STEGSEATTVST----- 1128

Query: 1315 PSEIPLGTPSDGNLASSPTSGSTQITPTLTSSNTVGVHIPEMSTSLGKTALPSQALTITT 1374
                   T S+   AS+  S  T +  T++ + TV     E +TS   +A  S+A T +T
Sbjct: 1129 -------TSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTS---SAAGSEATTTST 1178

Query: 1375 FLCPEKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINT 1434
                  E+T+A  A +  T      S   T S S  +  +   T + +ST  S   + NT
Sbjct: 1179 ---EGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNT 1235

Query: 1435 TFSHLHSLRTQPEVTSVASFISESTQTFPESLSLSTAGLYNDGFTVLSDRITTAFSVPNV 1494
             F     + ++  + S AS   E T T       +T  +   G T  S   TT  S   V
Sbjct: 1236 AF----IIGSETTIASTASL--EPTATSLTGSETTTVSITASGATAAS---TTVSSTTFV 1286

Query: 1495 PTMLPRESSMATSTPIYQMSSLPVNVTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTA 1554
             T        AT   I  +++ P++ T  T  +++         SS TM PG        
Sbjct: 1287 LT-------KATDVSIQPITNTPMSGTRTTGTRLT-------ASSSVTMAPGM----DFT 1328

Query: 1555 TSGPMSEMSSIPVNNSAFTPATVSSDTSTRVGLFSTLLSSVTPRTTMTMQTSTLDVTPVI 1614
             S     +  I +N S    +T+ + ++T      T   S    T+ T Q    +  PV 
Sbjct: 1329 ASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPTSSTFQ----ETGPVS 1384

Query: 1615 YAGATSKNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGT 1674
                T     VS + T   +     I P+ +L P    L  +  V   +   +   F   
Sbjct: 1385 MGTNT-----VSMSHTPTNV-----IKPSGYLQPWAIILISLAAVVAAVGLSVGLSFCLR 1434

Query: 1675 TAFSPL 1680
              F PL
Sbjct: 1435 NLFFPL 1440



 Score =  190 bits (482), Expect = 2e-47
 Identities = 349/1551 (22%), Positives = 602/1551 (38%), Gaps = 193/1551 (12%)

Query: 249  MTTPSQITGVKPQNTAHSSTLLSQSIPIF--ATDYTTISYSNT-TSPPLETMTAQKILKT 305
            M++ + +      NT  +ST  S++  I   A++ TT S + + T+ P  T +   I+  
Sbjct: 1    MSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSI 60

Query: 306  LVDETATFAVDVLSTSSAISLPTQSISIDNTTNSMKKTKSPSSESTKTTKMVEAMATEIF 365
               E  T      ST+ + +    S     TT SM       SE+T +T   E     I 
Sbjct: 61   SGSEITT-----TSTAGSENTTVSSAGSGTTTASMA-----GSETTVSTAGSETTTVSIT 110

Query: 366  QPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFSTIESTSMSTTPCLKQKSTNT 425
               T       S  T NS  S+ + + S +    TT      E+T+  T       ++ T
Sbjct: 111  GTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTT 170

Query: 426  GA--LPISTAGQEFIESTAAGTVPWFTVEKTSPASTHVGTASSFPPEPVLISTAAPVDSV 483
            G+    + TAG E I  + AG+         S A +   T S+   E    STA      
Sbjct: 171  GSEMTTVFTAGSETITPSTAGS----ETTTVSTAGSETTTVSTTGSETTTASTA------ 220

Query: 484  FPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETTPAPRTAETELTSTNFQDVSLPRVEDA 543
                  A  + +   K++      T+ T   ETT     A TE + TN       +   A
Sbjct: 221  HSETTAASTMGSETTKVSTAGSETTVSTAGSETT----AASTEDSETNTAFTEDSKTTTA 276

Query: 544  MSTSMSKETSSKTFSFLTSFSFTGTE-SVQTVIDAEATR--TALTPEITLASTVAETMLS 600
             +T      +S T S  T  S  G+E ++ + I  E T+  TA +   T+ +  +ET+ +
Sbjct: 277  STTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRA 336

Query: 601  STITGRVYTQNTPTADGHLLTLMSTRSASTSKAPESGPTSTTDEAAHLFSSNE-----TI 655
            ST+     T +T  ++    ++M + +++ S       T++T+ +    +S E     T+
Sbjct: 337  STVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTV 396

Query: 656  WTSRPDQALLASMNTTTILTFVPNENFTSAFHENTTYTEYLSATTNITPLKASPEGKGTT 715
             T+  +   ++  ++ T  T       T+    +TT  E  +A+T  + +  +      T
Sbjct: 397  STTGSETTTVSITDSETTTTCTEGSEMTAV---STTVFETTTASTEGSEITIASTSDSET 453

Query: 716  ANDATTARYTTAVSKLTSPWFANFSIVSGTTSITNMPEFKLTTLLLKTIPMSTKPANELP 775
               +T    TT V+   S     ++  S TT+ +N     L T  + TI   T       
Sbjct: 454  TTASTEGSETTTVTTAGSETKTAYTTGSETTTASNT---GLETTTVFTIGSDT------- 503

Query: 776  LTPRETVVPSVDIISTLACIQPNFSTEESASETTQTEINGAIVFGGTTTPVPKSATTQRL 835
             T   T       +S         STE S + T  T        G  TT V    +T  L
Sbjct: 504  -TTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTT-------GSETTTV----STTGL 551

Query: 836  NATVTRKEATSHYLMRKSTIAAV-AEVSPFSTMLEVTDESAQRVTASVTVSSFPDIEKLS 894
              T T  E +       +T++   AE +  ST    T  ++   + + TVS+       +
Sbjct: 552  ETTTTSTEGS-----EMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTA 606

Query: 895  TPLDNKTATTEVRESWLLTKLVKTTPRSSYNEMTEMFNFNHTYVAHWTSETSEGISAGSP 954
            +  D++T +     S   T    TT   +    TE      T V+   SET+        
Sbjct: 607  STADSETTSASTTGS--ETTTASTTSSETTTASTE--GSETTTVSTTDSETTM-----VS 657

Query: 955  TSGSTHIFGEPLGASTTRISETSFSTTPTDRTATSLSDGILPPQPTAAHSSATPVPVTHM 1014
            T+GS        G+ TT +S T   TT +   + + +  I   + T   ++ +   +T  
Sbjct: 658  TTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITST 717

Query: 1015 FSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVPPLDQTASTT 1074
                +  +S+   ET    +E S    A +    S+ ++ S+T   T        TAST 
Sbjct: 718  EGSEITTASITGSETTTASTEGSETTTASTEG--SETTSASTTGSETT-------TAST- 767

Query: 1075 IVIVPTHGDLIRTTSEATVISV--RKTSMAV---PSLTETPFHSLRLSTPVTAKAETTLF 1129
                        T+SE T+ S+   +T+MA       T+    S +++T  T  +ETT+ 
Sbjct: 768  ------------TSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIA 815

Query: 1130 STSVDTVTPSTHTLVCSKPPPDNIPPA---SSTHVISTTSTPEATQPISQVEETSTYALS 1186
            ST+      ++ T   S    + IP +   S T   ++T   E T   ++  ET+T +  
Sbjct: 816  STT------ASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTE 869

Query: 1187 FPYTFSGGGVVASLATGTTETSVVDETTPSHISANKLTT--SVNSHISSSATYRVHTPVS 1244
               T +   + +   T +TE S   ETT +    ++ TT  +  S I++ +T    T  +
Sbjct: 870  SSETTTATTIGSETTTASTEGS---ETTTTSTEGSETTTASTEGSEITTVSTTGSETTTA 926

Query: 1245 IQLVTSTSVLSSDKDQMTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPET 1304
                + T+  S++  ++T        T+  T              G+ ++ ++  G  ET
Sbjct: 927  STEGSETTTASTEGSELT--------TVSTT--------------GSETITVSAEG-SET 963

Query: 1305 TKISSHQTHSPSEIPLGTPSDGNLASSPTSGSTQITPTLTSSNTVGVHIPEMSTSLGKTA 1364
            T +    T   SE    + +     +  T+GS   T ++  S T  V     S++  +T 
Sbjct: 964  TTV----TTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTV-----SSTGSETT 1014

Query: 1365 LPSQALTITTFLCPEKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSST 1424
              S   T TT    E   T+ +      T  +    +  T + + G +T+ V TT S +T
Sbjct: 1015 TVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETT 1074

Query: 1425 RISNPMDINTTFSHLHSLRTQPEVTSVASFISESTQTF----PESLSLSTAGLYNDGFTV 1480
              S   D+ TT     ++ T    T+ AS     T T      ++ + ST G      + 
Sbjct: 1075 TAST-ADLETT-----TVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVST 1128

Query: 1481 LSDRITTAFS----VPNVPTMLPRESSMATSTPIYQMSSLPVNVTAFTSKKVSDTPPIVI 1536
             S   TTA +    +  V T +   ++++T       SS   +    TS + S+T     
Sbjct: 1129 TSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTAST 1188

Query: 1537 TKSSKTMHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPATVSSDTSTR--VGLFSTLLSS 1594
              S  T          TA++      ++    +   TP++  S+T+T   +G  +T+ S+
Sbjct: 1189 AGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIAST 1248

Query: 1595 VTPRTTMTMQTSTLDVTPVIYA-GATSKNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTL 1653
             +   T T  T +   T  I A GAT+ +  VSS               TTF+  T+ T 
Sbjct: 1249 ASLEPTATSLTGSETTTVSITASGATAASTTVSS---------------TTFVL-TKATD 1292

Query: 1654 PFVKTVPTTIMAGIVTPFVGTTAFSPLSS------KSTGAISSIPKTTF--SPFLSATQQ 1705
              ++ +  T M+G  T     TA S ++        ++ A  ++P      S   ++T  
Sbjct: 1293 VSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMG 1352

Query: 1706 SSQADEATTLGILSGITNRSLSTVNSGTGVAL--TDTYSRITVPENMLSPT 1754
            +S    A  +   +G T    S+    TG     T+T S    P N++ P+
Sbjct: 1353 ASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNVIKPS 1403



 Score =  186 bits (471), Expect = 4e-46
 Identities = 344/1489 (23%), Positives = 577/1489 (38%), Gaps = 190/1489 (12%)

Query: 548  MSKETS--SKTFSFLTSFSFTGTESVQTVIDAEATRTALTPEITLASTVAETMLSSTITG 605
            MS ET+      S  T+ S TG+E+   +I A  T TA T         +ET        
Sbjct: 1    MSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAG-------SET-------- 45

Query: 606  RVYTQNTPTADGHLLTLMSTRSASTSKAPESGPTSTTDEAAHLFSSNETIWTSRPDQALL 665
                  TP+  G   T++S   +  +    +G  +TT  +A   ++  ++  S    +  
Sbjct: 46   -----TTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTA 100

Query: 666  ASMNTTTILTFVPNENFTSAFHENTTYTEYLSATTNITPLKASPEGKGTTANDATTARYT 725
             S  TT  +T        SA    TT     S+ T +T    S     +T    TT  Y 
Sbjct: 101  GSETTTVSITGT-ETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAY- 158

Query: 726  TAVSKLTSPWFANFSIVSGTTSITNMPEFKLTTLLLKTIPMSTKPANELPLTPRETVVPS 785
            TA S+ T+             S T      + T   +TI  ST  +     T   T    
Sbjct: 159  TADSETTA------------ASTTGSEMTTVFTAGSETITPSTAGSE---TTTVSTAGSE 203

Query: 786  VDIISTLACIQPNFSTEESASETTQTEINGAIVFGGTTTPVPKSATTQRLNATVTRKEAT 845
               +ST         +E + + T  +E   A   G  TT V             T    T
Sbjct: 204  TTTVSTT-------GSETTTASTAHSETTAASTMGSETTKVS------------TAGSET 244

Query: 846  SHYLMRKSTIAAVAEVSPFSTMLEVTDESAQRVTASVTVSSFPDIEKLSTPLDNKTATTE 905
            +       T AA  E S  +T      E ++  TAS T   F      +T  +   A+T 
Sbjct: 245  TVSTAGSETTAASTEDSETNTAF---TEDSKTTTASTT--GFETTAASTTGSEPTMASTM 299

Query: 906  VRESWLLTKLVKTTPR--SSYNEMTEMFNFNHTYVAHWT--SETSEGISAGSPTSGSTHI 961
              E+ + + +   T +  ++ +E+T +F      +   T  SET+   + GS T+ +  I
Sbjct: 300  GSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETT-TASI 358

Query: 962  FGEPLGASTTRISETSFSTTPTDRTATSLSDGILPPQPTAAHSSATPVPVTHMFSLPVNG 1021
             G      +T  SET+ ++T    T T+ ++G          S AT V  T   +  V  
Sbjct: 359  MGSETSTDSTTGSETTTASTEGSETTTASTEG----------SEATTVSTTGSETTTV-- 406

Query: 1022 SSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVPPLDQTASTTIVIVPTH 1081
             S+   ET  T +E S +  A ST+V       ++T  T      +  T+ +      T 
Sbjct: 407  -SITDSETTTTCTEGSEMT-AVSTTVFE-----TTTASTEGSEITIASTSDSETTTASTE 459

Query: 1082 GDLIRTTSEATVISVRKTSMAVPSLTETPFHS-LRLSTPVTAKAETTLFS-----TSVDT 1135
            G    TT+  T  S  KT+    S T T  ++ L  +T  T  ++TT  S     T+  +
Sbjct: 460  GS--ETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVS 517

Query: 1136 VTPSTHTLVCSKPPPDNI--PPASSTHVISTT---STPEATQPISQVEETSTYALSFPYT 1190
             T S  T V ++   +       S T  +STT   +T  +T+       ++T A +   +
Sbjct: 518  ATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDS 577

Query: 1191 FSGGGVVASLATG--TTETSVVDETTPSHISANKLTTSVNS----HISSSATYRVHTPVS 1244
              G G  A+   G  TT  S  D    +  +A+  TTS ++      ++S T    T  S
Sbjct: 578  TEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTAS 637

Query: 1245 IQLVTSTSVLSSDKDQMTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGF--- 1301
             +   +T+V ++D +   +S   + RT+  TE S +     + S  T S E + T     
Sbjct: 638  TEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSI 697

Query: 1302 --PETTKISSHQTHSP------SEIPLGTPSDGNLASSPTSGSTQITPT-----LTSSNT 1348
               ETTK+S+  + +       SEI   + +     ++ T GS   T +      TS++T
Sbjct: 698  TGSETTKVSTTGSETTITSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSAST 757

Query: 1349 VGVHIPEMSTSLGKTALPSQALTITTFLCPEKESTSALPAYTPRTVEMIVNSTYVTHSVS 1408
             G      ST+  +T + S   + TT        T+ +   + +   +   ++  T + +
Sbjct: 758  TGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 817

Query: 1409 YGQDTSFV---------------DTTTSSSTRISNPMDINTTFSHLHSLRTQPEVTSVAS 1453
               +T+ V               +TTT++ST  S     +T  S   +  T+   T+ A+
Sbjct: 818  TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT 877

Query: 1454 FISESTQTF----PESLSLSTAGLYNDGFTVLSDRITTAFSVPNVPTMLPRESSMATSTP 1509
             I   T T      E+ + ST G      +     ITT  +  +  T    E S  T+  
Sbjct: 878  TIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 937

Query: 1510 IYQMSSLPVNVTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTATSGPMSEMSSIPVNN 1569
                    V+ T   +  VS        + S+T     + S  T  S   SE +++    
Sbjct: 938  TEGSELTTVSTTGSETITVS-------AEGSETTTVTTMGSETTTASTAGSETTTVSTAG 990

Query: 1570 SAFTPATVSSDTSTRV---GLFSTLLSSVTPRTTMTMQTSTLDVTPVIYAGATSKNKMVS 1626
            S  T A++    +T V   G  +T +S+    TT+T  T   + T V  AG+ +     +
Sbjct: 991  SETTTASIEGSETTTVSSTGSETTTVSTTGTETTIT-STEGSETTTVTTAGSETTAVYTT 1049

Query: 1627 SAFTTEMIEAPSRITPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSPLSSKSTG 1686
             + TT      S  T T   + +E T      + TT ++   T   GTT  S   S++T 
Sbjct: 1050 GSETTTTSTEGSE-TTTVSTTGSETTTASTADLETTTVS---TSGSGTTTASTAGSETTT 1105

Query: 1687 AISSIPKTTFSPFLSATQQSSQADEATTLGILSGITNRSLSTVNSGTGV--ALTDTYSRI 1744
               +  KTT +        S++  EATT+   S  T  + +T +  T V   +++T +  
Sbjct: 1106 VYITGSKTTTA--------STEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVS 1157

Query: 1745 TVPENMLSPTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLLEK 1804
            T+     + + A S  T+ + + S + T+  + S  T    T +   S  T   TS  E 
Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETT----TASTAGSETTTASTSGSET 1213

Query: 1805 TSLTNYATSLNTPVSYPPWT------------PSSATL-PSLTSFVYSPHSTEAEISTPK 1851
             +     +  +TP S    T             S+A+L P+ TS   S  +T +  ++  
Sbjct: 1214 NTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGA 1273

Query: 1852 TSPPPTSQMVEFPVLGTRMTSSNTQPLLMTSWNIPTAEGSQFPISTTINV-PTSNEMETE 1910
            T+   T     F +  T+ T  + QP+  T  +     G++   S+++ + P  +   + 
Sbjct: 1274 TAASTTVSSTTFVL--TKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASA 1331

Query: 1911 TLHLVPGPLSTFTASQTGLVSKDVMAMSSIPMSGILPNHGLSENPSLST 1959
              H VPG       + +GL +  + A S+    G+    G +  P+ ST
Sbjct: 1332 ASHTVPG----IVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPTSST 1376



 Score =  168 bits (425), Expect = 9e-41
 Identities = 290/1321 (21%), Positives = 524/1321 (39%), Gaps = 194/1321 (14%)

Query: 953  SPTSGSTHIFGEPLGASTTRISETSFSTTPTDRTATSLSDGILPPQPTAAHSSATPVPVT 1012
            +P +GS        G+ TT I   +  TT    TA++       P PT + ++       
Sbjct: 8    APAAGSNTTTASTTGSETTTILIKASETT----TASTAGSETTTPSPTGSQTTI------ 57

Query: 1013 HMFSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVPPLDQTAS 1072
                + ++GS +    T    SE +T++ A S +  + ++  S TT++TA       + +
Sbjct: 58   ----VSISGSEITT--TSTAGSENTTVSSAGSGTTTASMAG-SETTVSTA------GSET 104

Query: 1073 TTIVIVPTHGDLIR-----------TTSEATVISVR----KTSMAVPSLTETPF--HSLR 1115
            TT+ I  T   ++            T+SE TV S       T   V S T T +   S  
Sbjct: 105  TTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSET 164

Query: 1116 LSTPVTAKAETTLFSTSVDTVTPSTHTLVCSKPPPDNIPPASSTHVISTTSTPEATQPIS 1175
             +   T    TT+F+   +T+TPST                S T  +STT +   T   +
Sbjct: 165  TAASTTGSEMTTVFTAGSETITPST----AGSETTTVSTAGSETTTVSTTGSETTTASTA 220

Query: 1176 QVEETSTYALSFPYTFSGGGVVASLATGTTETSVVDETTPSHISANKLTTSV--NSHISS 1233
              E T+   +    T      V++  + TT ++   ETT +    ++  T+   +S  ++
Sbjct: 221  HSETTAASTMGSETT-----KVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTT 275

Query: 1234 SATYRVHTPVSIQLVTSTSVLSSDKDQMTISLGKTPRTMEVTEMSPSKNSFISYSRGTPS 1293
            ++T    T  +    +  ++ S+   + T++    P T +V+  S    +   ++ G+ +
Sbjct: 276  ASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTV--FAAGSET 333

Query: 1294 LEMTDTGFPETTKISSHQTHSPSEIPLG--TPSDGNLASSPTSGSTQITPTLTSSNTVGV 1351
            +  +  G  ETT +S+  + + +   +G  T +D    S  T+ ST+ + T T+S T G 
Sbjct: 334  IRASTVG-SETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTAS-TEGS 391

Query: 1352 HIPEMSTSLGKTALPSQALTITTFLCPEKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQ 1411
                +ST+  +T   S   + TT  C E    +A+      T          T + + G 
Sbjct: 392  EATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFET----------TTASTEGS 441

Query: 1412 DTSFVDTTTSSSTRISNPMDINTTFSHLHSLRTQPEVTSVASFISESTQTFPESLSLSTA 1471
            + +   T+ S +T  S      TT            VT+  S    +  T  E+ + S  
Sbjct: 442  EITIASTSDSETTTASTEGSETTT------------VTTAGSETKTAYTTGSETTTASNT 489

Query: 1472 GLYNDGFTVLSDRITTAFSVPNVPTMLPRESSMATSTPIYQMSSLPVNVTAFTSKKVSDT 1531
            GL            TT F++ +  T    E S  T+     +S+    +T  +++   +T
Sbjct: 490  GL----------ETTTVFTIGSDTTTASTEGSETTA-----VSATGSEMTTVSTEGSENT 534

Query: 1532 PPIVITKSSKTMHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPATVSSDTSTRVGLFSTL 1591
                    + T+    L++  T+T G  SEM+++    +  T  +     +T      + 
Sbjct: 535  TVSTTGSETTTVSTTGLETTTTSTEG--SEMTTVSTTGAETTTDSTEGSGTTAASTAGSE 592

Query: 1592 LSSVTPRTTMTMQTSTLDVTPVIYAGATSKNKMVSSAFTTEMIEAPSRITPTTFLSPTEP 1651
             ++V+   +     ST D +    A  T      +S  ++E   A +  + TT +S T+ 
Sbjct: 593  TTTVSTADSENTTASTAD-SETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDS 651

Query: 1652 TLPFVKTVPTTIMAGIVTPFVGTTAFSPLSSKSTGAISSIPKTTFSPFLSATQQSSQADE 1711
                             T  V TT     S ++  +      TT S   S T  S++   
Sbjct: 652  E----------------TTMVSTTG----SERTITSTEGSETTTVSATGSETTVSTEGSG 691

Query: 1712 ATTLGILSGITNRSLSTVNSGTGVALTD----TYSRITVPENMLSPTHADSLHTSFNIQV 1767
             TT+ I    T + +ST  S T +  T+    T + IT  E   + T      T+     
Sbjct: 692  TTTVSITGSETTK-VSTTGSETTITSTEGSEITTASITGSETTTASTEGSETTTA----- 745

Query: 1768 SPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLL-EKTSLTNYATSLNTPVSYPPWTPS 1826
              S    ++ S  T   +TTT   +S+   M S++  +T++ +   S  T VS       
Sbjct: 746  --STEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVS------- 796

Query: 1827 SATLPSLTSFVYSPHSTEAEISTPKTSPPPTSQMVEFPVLGTRMTSSNTQPLLMTSWNIP 1886
            +A+    T F  +  +T A  +  +T+   T+     P       ++ T     +     
Sbjct: 797  TASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTA 856

Query: 1887 TAEGSQFPISTTINVPTSNEMETETLHLVPGPLSTFTASQTGLVSKDVMAMSSIPMSGIL 1946
            + EGS+    TT     S+E  T T        ++   S+T   S +    ++    G  
Sbjct: 857  STEGSE----TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEG-- 910

Query: 1947 PNHGLSENPSLSTSLRAITSTLADVKHTFEKMTTSVTPGTTLPSILSGATSGSVISKSPI 2006
                 SE  ++ST+    T+   +   T    TT+ T G+ L ++ +  +    +S    
Sbjct: 911  -----SEITTVSTTGSETTTASTEGSET----TTASTEGSELTTVSTTGSETITVSAEGS 961

Query: 2007 LTWLLSSLPS--------GSPPATVSNAPHVMTSSTVEVSKSTFLTSDMISAHPFTNLTT 2058
             T  ++++ S        GS   TVS A    T++++E S++T ++S           T 
Sbjct: 962  ETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSS-----------TG 1010

Query: 2059 LPSATMSTILTRTIPTPTLGGITTGFPTSLPMSINVTDDIVYISTHPEASSRTTITANPR 2118
              + T+ST  T T  T T G  TT   T+       ++     +T  E ++ +T  +   
Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTA------GSETTAVYTTGSETTTTSTEGSETT 1064

Query: 2119 TVSHPSSFSRKTMSPSTTDHTLSVGAMPLPSSTITSSWNRIPTASSPSTLIIPKPTLDSL 2178
            TVS   S   +T + ST D         L ++T+++S +   TAS+  +    + T   +
Sbjct: 1065 TVSTTGS---ETTTASTAD---------LETTTVSTSGSGTTTASTAGS----ETTTVYI 1108

Query: 2179 LNIMTTTSTVPGASFPLISTGVTYPFTA-TVSSPISSFFETTWLDSTPSFLSTEASTSPT 2237
                TTT++  G+    +ST  +   TA T  S +++ F T    +T S + +EA+TS  
Sbjct: 1109 TGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSA 1168

Query: 2238 A 2238
            A
Sbjct: 1169 A 1169



 Score =  164 bits (415), Expect = 1e-39
 Identities = 318/1440 (22%), Positives = 558/1440 (38%), Gaps = 135/1440 (9%)

Query: 852  KSTIAAVAEVSPFSTMLEVTDESAQRVTASVTVSSFPDIEKLSTPLDNKTATTEVRESWL 911
            ++T+A  A  +  +     ++ +   + AS T ++     + +TP    + TT V  S  
Sbjct: 4    ETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISG- 62

Query: 912  LTKLVKTTPRSSYNEMTEMFNFNHTYVAHWTSETSEGISAGSPTS-----GSTHIFGEPL 966
             +++  T+   S N          T  +   SET+   +AGS T+     G+       +
Sbjct: 63   -SEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVS-TAGSETTTVSITGTETTMVSAM 120

Query: 967  GASTTRISETSFSTTPTD----RTATSLSDGILPPQPTAAHSSATPVPVT--HMFSLPVN 1020
            G+ TT  S TS  TT T      T T  + G        A S  T    T   M ++   
Sbjct: 121  GSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180

Query: 1021 GSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVPPLDQTASTTIVIVPT 1080
            GS  +   T    SE +T++ A S +     +   +TT +TA     + TA++T+    T
Sbjct: 181  GSETITPST--AGSETTTVSTAGSETTTVSTTGSETTTASTA---HSETTAASTMGSETT 235

Query: 1081 HGDLIRTTSEATVISVRKTSMAVPSLTETPFHSLRLSTPVTAKAETTLFSTSVDTVTPST 1140
                + T    T +S   +     S  ++  ++       T  A TT F T+  + T S 
Sbjct: 236  K---VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSE 292

Query: 1141 HTLVCSKPPPDNIPPASSTHVISTTSTPEATQPISQVEETSTYALSFPYTFSGGGVVASL 1200
             T+  +           S   +++T  PE T+  +   E +T        F+ G      
Sbjct: 293  PTMASTM---------GSETTMASTIGPETTKVSTASSEVTT-------VFAAGSETIRA 336

Query: 1201 ATGTTETSVVD----ETTPSHISANKLTT--SVNSHISSSATYRVHTPV-SIQLVTSTSV 1253
            +T  +ET+ V     ETT + I  ++ +T  +  S  ++++T    T   S +   +T+V
Sbjct: 337  STVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTV 396

Query: 1254 LSSDKDQMTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTH 1313
             ++  +  T+S+  +  T   TE             G+    ++ T F ETT  S+    
Sbjct: 397  STTGSETTTVSITDSETTTTCTE-------------GSEMTAVSTTVF-ETTTASTEG-- 440

Query: 1314 SPSEIPLGTPSDGNLASSPTSGSTQITPTLTSSNTVGVHIP-EMSTSLGKTALPSQAL-- 1370
              SEI + + SD    ++ T GS   T T   S T   +     +T+   T L +  +  
Sbjct: 441  --SEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFT 498

Query: 1371 --TITTFLCPEKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTT----TSSST 1424
              + TT    E   T+A+ A       +    +  T   + G +T+ V TT    T++ST
Sbjct: 499  IGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTST 558

Query: 1425 RISNPMDINTTFSHLHSLRTQPEVTSVASFISESTQTFP----ESLSLSTAGLYNDGFTV 1480
              S    ++TT +   +  T+   T+ AS     T T      E+ + STA       + 
Sbjct: 559  EGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSAST 618

Query: 1481 LSDRITTAFSVPNVPTMLPRESSMATSTPIYQMSSLPVNVTA----FTSKKVSDTPPIVI 1536
                 TTA +  +  T    E S  T+       +  V+ T      TS + S+T  +  
Sbjct: 619  TGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSA 678

Query: 1537 TKSSKTMHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPATVSSDTSTRVGLFSTLLSSVT 1596
            T S  T+      +   + +G  +   S   + +  T    S  T+  +    T  +S  
Sbjct: 679  TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTEGSEITTASITGSETTTASTE 738

Query: 1597 PRTTMTMQTSTLDVTPVIYAGATSKNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTLPFV 1656
               T T  T   + T     G+ +     +S+ TT      S  T  + +      +   
Sbjct: 739  GSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTA 798

Query: 1657 KTVPTTIMAGIVTPFVGTTAFSPLSSKSTGAISSIPKTTF-------------------- 1696
             +  TT+        + +T  S  ++ ST    +IP +T                     
Sbjct: 799  SSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTAST 858

Query: 1697 --SPFLSATQQSSQADEATTLG------ILSGITNRSLSTVNSGTGVALTDTYSRITVPE 1748
              S   +A+ +SS+   ATT+G         G    + ST  S T  A T+  S IT   
Sbjct: 859  EGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEG-SEITTVS 917

Query: 1749 NMLSPTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLLEKTSLT 1808
               S T   S   S     S   +   + S  T +   T +   S T  +T++  +T+  
Sbjct: 918  TTGSETTTASTEGSETTTASTEGSELTTVS-TTGSETITVSAEGSETTTVTTMGSETTTA 976

Query: 1809 NYATSLNTPVSYPPWTPSSATLP-SLTSFVYSPHSTEAEISTPKTSPPPTSQMVEFPVLG 1867
            + A S  T VS      ++A++  S T+ V S  S    +ST  T    TS   E     
Sbjct: 977  STAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITS--TEGSETT 1034

Query: 1868 TRMTSSNTQPLLMTSWNIPTAEGSQFPISTTINVPTSNEMETETLHLVPGPLSTFTASQT 1927
            T  T+ +    + T+ +  T   ++   +TT++   S      T  L    +ST + S T
Sbjct: 1035 TVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVST-SGSGT 1093

Query: 1928 GLVSKDVMAMSSIPMSGILPNHGLSENPSLSTSLRAITSTLADVKHTFEKMT---TSVTP 1984
               S      +++ ++G       +E  S +T++   +S       T  +MT   T+V+ 
Sbjct: 1094 TTASTAGSETTTVYITGSKTTTASTEG-SEATTVSTTSSETTTASTTGSEMTTVFTTVSE 1152

Query: 1985 GTTLPSILSGATSGSVISKSPILTWLLSSLPSGSPPATVSNAPHVMTSSTVEVSKSTFLT 2044
             TT+ +I S AT+ S        T        GS   T S A    T+++   S++T  +
Sbjct: 1153 TTTVSTIGSEATTSSAAGSEATTT-----STEGSETTTASTAGSETTTASTAGSETTTAS 1207

Query: 2045 ---SDMISAHPFTNLTTLPSATMSTILTRTI--PTPTLGGITTGFPTSLPMSINVTDDIV 2099
               S+  +A    + T+ PS+  S   T  I     T+    +  PT+  ++ + T  + 
Sbjct: 1208 TSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVS 1267

Query: 2100 YISTHPEASSRTTITANPRTVSHPSSFSRKTMSPSTTDHTLSVGAMPLPSSTITSSWNRI 2159
              ++   A+S TT+++    ++  +  S + ++ +    T + G     SS++T +    
Sbjct: 1268 ITASGATAAS-TTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMD 1326

Query: 2160 PTASSPSTLIIPKPTLDSLLNIMTTTSTVPGASFPLISTGVTYPFTATVSSPISSFFETT 2219
             TAS+ S  +   P +  +LN     ++  GAS    + GV    T +   P SS F+ T
Sbjct: 1327 FTASAASHTV---PGI--VLNTSGLGTSTMGASSTTSAHGVR-TTTGSTREPTSSTFQET 1380



 Score =  148 bits (373), Expect = 9e-35
 Identities = 268/1153 (23%), Positives = 444/1153 (38%), Gaps = 135/1153 (11%)

Query: 1204 TTETSVVDETTPSHISANKLTTSVNSHISS---SATYRVHTPVSIQLVTSTSVLSSDKDQ 1260
            TT ++   ETT   I A++ TT+  +   +   S T    T VSI     T+  ++  + 
Sbjct: 16   TTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSEN 75

Query: 1261 MTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSPSEIPL 1320
             T+S   +  T     M+ S+ +  +    T ++ +T T   ETT +S+          +
Sbjct: 76   TTVSSAGSGTT--TASMAGSETTVSTAGSETTTVSITGT---ETTMVSA----------M 120

Query: 1321 GTPSDGNLASSPTSGSTQITPTLTSSNTVGVHIPEMSTSLGKTALPSQALTITTFLCPEK 1380
            G+ +  N   S TS  T +T T  S  T       +ST   +T         TT    + 
Sbjct: 121  GSETTTN---STTSSETTVTSTAGSETTT------VSTVGSET---------TTAYTADS 162

Query: 1381 ESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINTTFSHLH 1440
            E+T+A    +  T      S  +T S + G +T+ V T  S +T +S      TT S  H
Sbjct: 163  ETTAASTTGSEMTTVFTAGSETITPSTA-GSETTTVSTAGSETTTVSTTGSETTTASTAH 221

Query: 1441 SLRTQPEVTSVASFISESTQ--TFPESLSLSTAGLYNDGFTVLSDRITTAFSVPNVPTML 1498
            S     E T+ ++  SE+T+  T     ++STAG      +       TAF+        
Sbjct: 222  S-----ETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFT-------- 268

Query: 1499 PRESSMATSTPIYQMSSLPVNVTAFTSKKVSDT---PPIVITKSSKTMHPGCLKSPCTAT 1555
              E S  T+           + T F +   S T   P +  T  S+T     +    T  
Sbjct: 269  --EDSKTTTA----------STTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKV 316

Query: 1556 SGPMSEMSSI-PVNNSAFTPATVSSDTSTRVGLFSTLLSSVTPRTTMTMQTSTLDVTPVI 1614
            S   SE++++    +     +TV S+T+T     ST  S  T  + M  +TST   T   
Sbjct: 317  STASSEVTTVFAAGSETIRASTVGSETTT----VSTTGSETTTASIMGSETSTDSTT--- 369

Query: 1615 YAGATSKNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGT 1674
                T+      S  TT   E     T +T  S T           TT   G     V T
Sbjct: 370  -GSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVST 428

Query: 1675 TAFSPLSSKSTGAISSIPKTTFSPFLSATQQSSQADEATTLG--ILSGITNRSLSTVNSG 1732
            T F   ++ + G+  +I  T+ S   +A+ + S+    TT G    +  T  S +T  S 
Sbjct: 429  TVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASN 488

Query: 1733 TGVALTDTYSRITVPENMLSPTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFS 1792
            TG+  T  ++       + S T   S   S    VS + +   + S       T +   S
Sbjct: 489  TGLETTTVFT-------IGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGS 541

Query: 1793 SNTRKMTSLLEKTSLTNYATSLNTPVSYPPWTPSSATLPSLTSFVYSPHSTEAEISTPKT 1852
              T   T+ LE T+ +   + + T  +    T + +T  S T+   +  S    +ST   
Sbjct: 542  ETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTAD- 600

Query: 1853 SPPPTSQMVEFPVLGTRMTSSNTQPLLMTSWNIPTA--EGSQFPISTTINVPTSNEMETE 1910
            S   T+   +        T S T     TS    TA  EGS+    +T +  T+    T 
Sbjct: 601  SENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTG 660

Query: 1911 TLHLVPGP--LSTFTASQTG---LVSKDVMAMSSIPMSGILPNHGLSENPSLST--SLRA 1963
            +   +       T T S TG    VS +    +++ ++G       SE   +ST  S   
Sbjct: 661  SERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITG-------SETTKVSTTGSETT 713

Query: 1964 ITST----LADVKHTFEKMTTSVTPGTTLPSILSGATSGSVISKSPILTWLLSSLPSGSP 2019
            ITST    +     T  + TT+ T G+   +  +  +  +  S +   T   S+  S + 
Sbjct: 714  ITSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETT 773

Query: 2020 PATVSNAPHVMTSST-VEVSKSTFLTSDMISAHPFTNLTTLPSAT------MSTILTRTI 2072
             A++  +   M S+   E +K +  +S M +     + TT+ S T      +ST  + TI
Sbjct: 774  MASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETI 833

Query: 2073 PTPTLGGITTGFPTSLPMSINVTDDIVYISTHPEASSRTTITANPRTVSHPSSFSRKTMS 2132
            P  T G  TT        +   T+     +   E S  TT +      +  ++   +T +
Sbjct: 834  PASTAGSETT--------TTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTT 885

Query: 2133 PSTT-DHTLSVGAMPLPSSTITSSWNRIPTASSPSTLIIPKPTLDSLLNIMTTTSTVPGA 2191
             ST    T +       ++T ++  + I T S+  +    + T  S     TTT++  G+
Sbjct: 886  ASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGS----ETTTASTEGSETTTASTEGS 941

Query: 2192 SFPLISTGVTYPFTATVSSPISSFFETTWLDSTPSFLSTEASTSPTATK--STVSFYNVE 2249
                +ST  T   T TVS+  S     T + S  +  ST  S + T +   S  +  ++E
Sbjct: 942  ELTTVST--TGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIE 999

Query: 2250 MSFSVFVEEPRIPITSVINEFTENSLNSIFQNSEFSLATLETQIKSRDISEEEMVMDRAI 2309
             S +  V       T+V    TE ++ S   +   ++ T  ++  +   +  E       
Sbjct: 1000 GSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSE-----TT 1054

Query: 2310 LEQREGQEMATIS 2322
                EG E  T+S
Sbjct: 1055 TTSTEGSETTTVS 1067



 Score =  145 bits (365), Expect = 8e-34
 Identities = 274/1150 (23%), Positives = 454/1150 (39%), Gaps = 122/1150 (10%)

Query: 1154 PPASSTHVISTTSTPEATQPISQVEETSTYALSFPYTFSGGGVVASLATGTTETSVVDET 1213
            P A S    ++T+  E T  + +  ET+T + +   T             TT +    +T
Sbjct: 9    PAAGSNTTTASTTGSETTTILIKASETTTASTAGSET-------------TTPSPTGSQT 55

Query: 1214 TPSHISANKLTT-----SVNSHISSSATYRVHTPVSIQLVTSTSVLSSDKDQMTISLGKT 1268
            T   IS +++TT     S N+ +SS+ +    T  +    + T+V ++  +  T+S+  T
Sbjct: 56   TIVSISGSEITTTSTAGSENTTVSSAGS---GTTTASMAGSETTVSTAGSETTTVSITGT 112

Query: 1269 PRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSP------SEIPLGT 1322
              TM     S +  +  + S  T    +T T   ETT +S+  + +       SE    +
Sbjct: 113  ETTMVSAMGSETTTNSTTSSETT----VTSTAGSETTTVSTVGSETTTAYTADSETTAAS 168

Query: 1323 PSDGNLASSPTSGSTQITPTLTSS-----NTVGVHIPEMSTSLGKTALPSQALTITTFLC 1377
             +   + +  T+GS  ITP+   S     +T G     +ST+  +T   S A + TT   
Sbjct: 169  TTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAAS 228

Query: 1378 PE-KESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDT------------TTSSST 1424
                E+T    A +  TV    + T    +     +T+F +             TT++ST
Sbjct: 229  TMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST 288

Query: 1425 RISNPMDINTTFSHLHSLRT-QPEVTSVASFISESTQTFP---ESLSLSTAGLYNDGFTV 1480
              S P   +T  S      T  PE T V++  SE T  F    E++  ST G      + 
Sbjct: 289  TGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVST 348

Query: 1481 LSDRITTAFSVPNVPTMLPRESSMATSTPIYQMSSLPVNVTAFTSKKVSDTPPIVITKSS 1540
                 TTA S+    T     +   T+T   + S      TA T    + T   V T  S
Sbjct: 349  TGSETTTA-SIMGSETSTDSTTGSETTTASTEGSE---TTTASTEGSEATT---VSTTGS 401

Query: 1541 KTMHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPATVSSDTSTRVGLFSTLLSSVTPRTT 1600
            +T       S  T T    SEM++  V+ + F   T S++ S         ++S +   T
Sbjct: 402  ETTTVSITDSETTTTCTEGSEMTA--VSTTVFETTTASTEGS------EITIASTSDSET 453

Query: 1601 MTMQTSTLDVTPVIYAGATSKNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTLPFVKTVP 1660
             T  T   + T V  AG+ +K    + + TT         T T F   ++ T    +   
Sbjct: 454  TTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT-TVFTIGSDTTTASTEGSE 512

Query: 1661 TTIMAGIVTPFVGTTAFSPLSSKSTGAISSIPKTTFSPF-LSATQQSSQADEATTLGILS 1719
            TT ++   +    TT  +  S  +T + +    TT S   L  T  S++  E TT+   +
Sbjct: 513  TTAVSATGSEM--TTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVST-T 569

Query: 1720 GITNRSLSTVNSGTGVALTDTYSRITVP----ENMLSPTHADSLHTSFNIQVSP----SL 1771
            G    + ST  SGT  A T      TV     EN  + T ADS  TS +   S     S 
Sbjct: 570  GAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAST-ADSETTSASTTGSETTTAST 628

Query: 1772 TSFKSASGPTKNVKTTT-NCFSSNTRKMTSLLEKTSLTNYATSLNTPVSYPPWTPSSATL 1830
            TS ++ +  T+  +TTT +   S T  +++   + ++T+   S  T VS      + +T 
Sbjct: 629  TSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTE 688

Query: 1831 PSLTSFVYSPHSTEAEISTPKTSPPPTS----QMVEFPVLGTRMTSSNTQPLLMTSWNIP 1886
             S T+ V    S   ++ST  +    TS    ++    + G+  T+++T+    T+    
Sbjct: 689  GSGTTTVSITGSETTKVSTTGSETTITSTEGSEITTASITGSETTTASTEGSETTT---A 745

Query: 1887 TAEGSQFPISTTINVPTSNEMETETLHLVPGPLSTFTASQTGLVSKDVMAMSSIPMSGIL 1946
            + EGS+    TT    T +E  T +       +++   S+T + S      + +  +   
Sbjct: 746  STEGSE----TTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSK 801

Query: 1947 PNHGLSENPSLSTSLRAITSTLADVKHTFEKMTTSVTPGTTLPSILSGATSGSVISKSPI 2006
                 +EN     S   I ST A      E  T S     T+P+  +G+ + +  S    
Sbjct: 802  MTTVFTEN-----SETTIASTTAS-----ETTTVSTAGSETIPASTAGSETTTTTSTEGS 851

Query: 2007 LTWLLSSLPSGSPPATVSNAPHVMTSSTVEVSKSTFLT---SDMISAHPFTNLTTLPSA- 2062
             T   S+   GS   T S      T++T   S++T  +   S+  +     + TT  S  
Sbjct: 852  ETTTAST--EGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTE 909

Query: 2063 -----TMSTILTRTIPTPTLGGITTGFPTSLPMSINV-TDDIVYISTHPEASSRTTITAN 2116
                 T+ST  + T    T G  TT   T       V T     I+   E S  TT+T  
Sbjct: 910  GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTM 969

Query: 2117 PRTVSHPSSFSRKTMSPSTT-DHTLSVGAMPLPSSTITSSWNRIPTASSPSTLIIPKPTL 2175
                +  S+   +T + ST    T +       ++T++S+ +   T S+  T    + T+
Sbjct: 970  GSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGT----ETTI 1025

Query: 2176 DSLLNIMTTTSTVPGASFPLI-STGVTYPFTATVSSPISSFFETTWLDSTPSFLSTEAST 2234
             S     TTT T  G+    + +TG     T+T  S  ++   T    +T S    E +T
Sbjct: 1026 TSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTT 1085

Query: 2235 SPTATKSTVS 2244
              T+   T +
Sbjct: 1086 VSTSGSGTTT 1095



 Score = 88.2 bits (217), Expect = 1e-16
 Identities = 148/643 (23%), Positives = 235/643 (36%), Gaps = 78/643 (12%)

Query: 219  IPTVDRTLRCFVPENMTIQEKSTTVSQQIDMTTPSQITGVKPQNTAHSSTLLSQSIPIFA 278
            + T    +     EN      STT S+   ++T    T   P +TA S T  + S     
Sbjct: 795  VSTASSKMTTVFTENSETTIASTTASETTTVSTAGSET--IPASTAGSETTTTTSTEGSE 852

Query: 279  TDYTTISYSNTTSPPL---ETMTAQKI------LKTLVDETATFAVDVLSTSSAISLPTQ 329
            T   +   S TT+      ET TA  I        T   ET T + +   T++A    T+
Sbjct: 853  TTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTA---STE 909

Query: 330  SISIDNTTNSMKKTKSPSSESTKTTKMVEAMATEIFQPPTPSNFLSTSRFTKNSVVSTTS 389
               I   + +  +T + S+E ++TT      +TE  +  T S        T  S   T S
Sbjct: 910  GSEITTVSTTGSETTTASTEGSETT----TASTEGSELTTVS--------TTGSETITVS 957

Query: 390  AIKSQSAVTKTTSLFSTIESTSMSTTPCLKQKSTNTGALPISTAGQEFIESTAAGTVPWF 449
            A  S++    T    +T  ST+ S T              +STAG E   ++  G+    
Sbjct: 958  AEGSETTTVTTMGSETTTASTAGSET------------TTVSTAGSETTTASIEGS-ETT 1004

Query: 450  TVEKTSPASTHVGTASSFPPEPVLISTAAPVDSVFPRNQTAFPLATTDMKIAFTVHSLTL 509
            TV  T   +T V T            T   + S      T    A ++    +T  S T 
Sbjct: 1005 TVSSTGSETTTVSTT----------GTETTITSTEGSETTTVTTAGSETTAVYTTGSET- 1053

Query: 510  PTRLIETTPAPRTAETELTSTNFQDVSLPRVEDAMSTSMSKETSSKTFSFLTSFSFTGTE 569
                  TT +   +ET   ST   + +     D  +T++S   S       T+ S  G+E
Sbjct: 1054 ------TTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG-----TTTASTAGSE 1102

Query: 570  SVQTVIDAEATRTALTPEITLASTVAETMLSSTITGRVYTQNTPTADGHLLTLMSTRSAS 629
            +    I    T TA T E + A+TV+ T   +T         T +  G  +T + T  + 
Sbjct: 1103 TTTVYITGSKTTTAST-EGSEATTVSTTSSETT---------TASTTGSEMTTVFTTVSE 1152

Query: 630  TSKAPESGPTSTTDEAAHLFSSNETIWTSRPDQALLASMNTTTILTFVPNENFTSAFHEN 689
            T+     G  +TT  AA   ++  +   S    A  A   TTT  T   +E  T++   +
Sbjct: 1153 TTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAST-AGSETTTASTSGS 1211

Query: 690  TTYTEYLSATTNITPLKASPEGK-----GTTANDATTARYTTAVSKLTSPWFANFSIVSG 744
             T T   + +   TP  A  E       G+    A+TA      + LT       SI + 
Sbjct: 1212 ETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITAS 1271

Query: 745  TTSITNMPEFKLTTLLLKTIPMSTKPANELPLTPRETVVPSVDIISTLACIQPNFSTEES 804
              +  +      T +L K   +S +P    P++   T    +   S++        T  +
Sbjct: 1272 GATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASA 1331

Query: 805  ASETTQTEINGAIVFGGTTTPVPKSATTQRLNATV-TRKEATS 846
            AS T    +      G +T     + +   +  T  + +E TS
Sbjct: 1332 ASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPTS 1374


>gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score =  201 bits (511), Expect = 9e-51
 Identities = 352/1539 (22%), Positives = 585/1539 (38%), Gaps = 175/1539 (11%)

Query: 343  TKSPSSESTKTTKMVEAMATEIFQP-------PTPSNFLSTSRFTKNSVVSTTSAIKSQS 395
            T + ++ S  TT +++A  T            P+P+   +T      S ++TTS   S++
Sbjct: 16   TTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSEN 75

Query: 396  AVTKTTSLFSTIESTSMSTTPCLKQKSTNTGALPISTAGQEFIESTAAGTVPWFTVEKTS 455
                     +T+ S    TT      S  T    +STAG E    +  GT         S
Sbjct: 76   ---------TTVSSAGSGTTTASMAGSETT----VSTAGSETTTVSITGTETTMVSAMGS 122

Query: 456  PASTHVGTASSFPPEPVLISTAAPVDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIE 515
              +T+  T+S         S    V +V     TA+   +     + T   +T       
Sbjct: 123  ETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGS 182

Query: 516  TTPAPRTAETELTSTNFQDVSLPRVEDAMSTSMSKETSSKTFSFLTSFSFTGTESVQ-TV 574
             T  P TA +E T+ +        V    +T     T+S   S  T+ S  G+E+ + + 
Sbjct: 183  ETITPSTAGSETTTVSTAGSETTTVS---TTGSETTTASTAHSETTAASTMGSETTKVST 239

Query: 575  IDAEATRTALTPEITLASTV-AETMLSSTITGRVYTQNT-------PTADGHLLTLMSTR 626
              +E T +    E T AST  +ET  + T   +  T +T        +  G   T+ ST 
Sbjct: 240  AGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTM 299

Query: 627  SASTSKAPESGPTSTTDEAAHLFSSNETIWTSRPDQALLASM--NTTTILTFVPNENFTS 684
             + T+ A   GP +T    A   SS  T   +   + + AS   + TT ++   +E  T+
Sbjct: 300  GSETTMASTIGPETTKVSTA---SSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTA 356

Query: 685  AFHENTTYTEYLSATTNITPLKASPEGKGTTANDATTARYTTAVSKLTSPWFANFSIVSG 744
            +   + T T+   +TT      AS EG  TT      +  TT             S    
Sbjct: 357  SIMGSETSTD---STTGSETTTASTEGSETTTASTEGSEATTV------------STTGS 401

Query: 745  TTSITNMPEFKLTTLLLKTIPMSTKPANELPLTPRETVVPSVDIISTLACIQPNFSTEES 804
             T+  ++ + + TT   +   M+         T   T    + I ST        STE S
Sbjct: 402  ETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGS 461

Query: 805  ASETTQTEINGAIVFGGTTTPVPKSATTQRLNATVTRKEATSHYLMRKSTIAAVAEVSPF 864
             + T  T         G+ T    +  ++   A+ T  E T+ + +   T  A  E S  
Sbjct: 462  ETTTVTT--------AGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 513

Query: 865  -------STMLEVTDESAQRVTASVTVSSFPDIEKLSTPLDNKTATTEVRESWLLTKLVK 917
                   S M  V+ E ++  T S T S    +   +T L+  T +TE  E       V 
Sbjct: 514  TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVS--TTGLETTTTSTEGSE----MTTVS 567

Query: 918  TTPRSSYNEMTEMFNFNHTYVAHWTSETSEGISAGSPTSGSTHIFGEPLGASTTRISETS 977
            TT   +  + TE      T  +   SET+   +A S  + ++    E   ASTT  SET+
Sbjct: 568  TTGAETTTDSTE--GSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTG-SETT 624

Query: 978  FSTTPTDRTATSLSDGILPPQPTAAHSSATPVPVTHMFSLPVNGSSVVAEETEVTMSEPS 1037
             ++T +  T T+ ++G          S  T V  T               ++E TM   +
Sbjct: 625  TASTTSSETTTASTEG----------SETTTVSTT---------------DSETTMVSTT 659

Query: 1038 TLARAFSTSVLSDVSNLSSTTMTTALVPPLDQTASTTIVIVPTHGDLIRTT-SEATVISV 1096
               R  +++  S+ + +S+T   T +    + + +TT+ I  +    + TT SE T  S 
Sbjct: 660  GSERTITSTEGSETTTVSATGSETTV--STEGSGTTTVSITGSETTKVSTTGSETTTTST 717

Query: 1097 RKTSMAVPSLTETPFHSLRLSTPVTAKAETTLFSTSVDTVTPSTHTLVCSKPPPDNIPPA 1156
              + +   S+T +       +T  T  +ETT  ST   + T S  T              
Sbjct: 718  EGSEITTASITGS-----ETTTASTEGSETTTASTE-GSETTSASTTGSETTTASTTSSE 771

Query: 1157 SSTHVISTTSTPEATQPISQVEETSTYALSFPYTFSGGGVVASLATGTTETSVV----DE 1212
            ++   I  + T  A+   S+  + ST +      F+        +T  +ET+ V     E
Sbjct: 772  TTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSE 831

Query: 1213 TTPSHISANKLTTSVNSHISSSATYRVH----TPVSIQLVTSTSVLSSDKDQMTISLGKT 1268
            T P+  + ++ TT+ ++  S + T        T  S +   +T+  +   +  T S   +
Sbjct: 832  TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS 891

Query: 1269 PRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSPSEIPLGTPSDGNL 1328
              T   TE S +     + + G+    ++ TG  ETT  S+      SE    +     L
Sbjct: 892  ETTTTSTEGSETTT---ASTEGSEITTVSTTG-SETTTAST----EGSETTTASTEGSEL 943

Query: 1329 ASSPTSGSTQITPT-----LTSSNTVGVHIPEMSTSLGKTALPSQALTITTFLCPEKEST 1383
             +  T+GS  IT +      T+  T+G      ST+  +T   S A + TT    E   T
Sbjct: 944  TTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSET 1003

Query: 1384 SALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINTTFSHLHSLR 1443
            + + +    T  +    T  T + + G +T+ V T  S +T +       TT S   S  
Sbjct: 1004 TTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGS-- 1061

Query: 1444 TQPEVTSVASFISESTQTFPESLSLSTAGLYNDGFTVLS---DRITTAFSVPNVPTMLPR 1500
               E T+V++  SE+T      L  +T      G T  S      TT +   +  T    
Sbjct: 1062 ---ETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTAST 1118

Query: 1501 ESSMATSTPIYQMSSLPVNVTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTATSGPMS 1560
            E S AT+      ++     TA T+     T   V T  S+T     + S  T +S   S
Sbjct: 1119 EGSEATTV----STTSSETTTASTTGSEMTT---VFTTVSETTTVSTIGSEATTSSAAGS 1171

Query: 1561 EMSSIPVNNSAFTPA-TVSSDTSTRVGLFSTLLSSVTPRTTMTMQTSTLDVTPVIYAGAT 1619
            E ++     S  T A T  S+T+T     ST  S  T  +T   +T+T   T    +  +
Sbjct: 1172 EATTTSTEGSETTTASTAGSETTTA----STAGSETTTASTSGSETNTACTTGSETSTPS 1227

Query: 1620 SKNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSP 1679
            S     ++AF   +I + S I  T  L PT  +L   +T   +I A       G TA S 
Sbjct: 1228 SAGSETNTAF---IIGSESTIASTASLEPTATSLTGSETTTVSITAS------GATAAST 1278

Query: 1680 LSSKSTGAISSIPKTTFSPFLSATQQSSQADEATTLGILSGITNRSLSTVNSGTGVALTD 1739
              S +T  ++     +  P  +     ++          +G    + S+V    G+  T 
Sbjct: 1279 TVSSTTFVLTKATDVSIQPITNTPMSGTRT---------TGTRLTASSSVTMAPGMDFTA 1329

Query: 1740 TYSRITVPENMLSPTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMT 1799
            + +  TVP  +L   +   L TS     + S TS       T + +  T+     T  ++
Sbjct: 1330 SAASHTVPGIVL---NTSGLGTS--TMGASSTTSAHGVRTTTGSTREPTSSTFQETGPVS 1384

Query: 1800 SLLEKTSLTNYATSLNTPVSY-PPWTPSSATLPSLTSFV 1837
                  S+++  T++  P  Y  PW     +L ++ + V
Sbjct: 1385 MGTNTVSMSHTPTNVIKPSGYLQPWAIILISLAAVVAAV 1423



 Score =  194 bits (494), Expect = 9e-49
 Identities = 356/1506 (23%), Positives = 591/1506 (39%), Gaps = 195/1506 (12%)

Query: 235  TIQEKSTTVSQQIDMTTPSQITGVKPQ-NTAHSSTLLSQSIPIFATDYTTIS-YSNTTSP 292
            T   ++TTVS     TT + + G +   +TA S T    ++ I  T+ T +S   + T+ 
Sbjct: 70   TAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETT---TVSITGTETTMVSAMGSETTT 126

Query: 293  PLETMTAQKILKTLVDETATFAVDVLSTSSAISLPTQSISIDNTTNSM-------KKTKS 345
               T +   +  T   ET T +     T++A +  +++ +   T + M        +T +
Sbjct: 127  NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETIT 186

Query: 346  PSSESTKTTKMVEAMATEIFQPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFS 405
            PS+  ++TT +  A +       T S   +T+  T +S  +  S + S++    T    +
Sbjct: 187  PSTAGSETTTVSTAGSETTTVSTTGSE--TTTASTAHSETTAASTMGSETTKVSTAGSET 244

Query: 406  TIESTSMSTTPCLKQKS-TNTGALPIS---TAGQEFIESTAAGTVPWFTVEKTSPAST-- 459
            T+ +    TT    + S TNT     S   TA     E+TAA T    T  + + AST  
Sbjct: 245  TVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST----TGSEPTMASTMG 300

Query: 460  -HVGTASSFPPEPVLISTAAP-VDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETT 517
                 AS+  PE   +STA+  V +VF         +T   +      + T+ T   ETT
Sbjct: 301  SETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSE------TTTVSTTGSETT 354

Query: 518  PAP-RTAETELTSTNFQDVSLPRVEDAMSTSMSKETSSKTFSFLTSFSFTGTESVQTVID 576
             A    +ET   ST   + +    E + +T+ S E S  T     + S TG+E+    I 
Sbjct: 355  TASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEAT-----TVSTTGSETTTVSIT 409

Query: 577  AEATRTALTP--EITLASTVAETMLSSTITGRVYTQNTPTADGHLLTLMSTRSASTSKAP 634
               T T  T   E+T  ST             V+   T + +G  +T+ ST  + T+ A 
Sbjct: 410  DSETTTTCTEGSEMTAVSTT------------VFETTTASTEGSEITIASTSDSETTTAS 457

Query: 635  ESGPTSTTDEAAHLFSSNETIWT--SRPDQALLASMNTTTILTFVPNENFTSAFHENTTY 692
              G  +TT   A   S  +T +T  S    A    + TTT+ T     + T+A  E +  
Sbjct: 458  TEGSETTTVTTAG--SETKTAYTTGSETTTASNTGLETTTVFTI--GSDTTTASTEGSET 513

Query: 693  TEYLSATTNITPLKASPEGK-----GTTANDATTARYTTAVSKLTSPWFANFSIVS--GT 745
            T   +  + +T +  S EG       TT ++ TT   T   +  TS   +  + VS  G 
Sbjct: 514  TAVSATGSEMTTV--STEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGA 571

Query: 746  TSITNMPEFKLTTLL----LKTIPMSTKPANELPLTPRETVVPSVDIISTLACIQPNFST 801
             + T+  E   TT       +T  +ST  +         T   + D  +T A       +
Sbjct: 572  ETTTDSTEGSGTTAASTAGSETTTVSTADS-------ENTTASTADSETTSA---STTGS 621

Query: 802  EESASETTQTEINGAIVFGGTTTPVPKS-ATTQRLNATVTRKEATSHYLMRKSTIAAVAE 860
            E + + TT +E   A   G  TT V  + + T  ++ T + +  TS      +T++A   
Sbjct: 622  ETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGS 681

Query: 861  VSPFSTMLEVTDESAQRVTASVTVSSFPDIEKLSTPLDNKTATTEVRESWLLTKLV---K 917
             +  ST      E +   T S+T S   +  K+ST   ++T TT    S + T  +   +
Sbjct: 682  ETTVST------EGSGTTTVSITGS---ETTKVST-TGSETTTTSTEGSEITTASITGSE 731

Query: 918  TTPRSSYNEMTEMFNFNHTYVAHWTSETSEGISAGSPTS--------GSTHIFGEPLGAS 969
            TT  S+    T   +   +     ++  SE  +A + +S        GS       +G+ 
Sbjct: 732  TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSE 791

Query: 970  TTRISETS--FSTTPTDRTATSLSDGILPPQPTAAHSSATPVPVTHMFSLPVNGSSVVAE 1027
            TT++S  S   +T  T+ + T+++        T + + +  +P +   S     +S    
Sbjct: 792  TTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGS 851

Query: 1028 ETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVPPLDQTASTTIVIVPTHGDLIRT 1087
            ET    +E S    A + S  +  +    +  TTA     + T ++T             
Sbjct: 852  ETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTST------------E 899

Query: 1088 TSEATVISVRKTSMAVPSLT--ETPFHSLRLSTPVTAKAE----TTLFSTSVDTVTPS-- 1139
             SE T  S   + +   S T  ET   S   S   TA  E    TT+ +T  +T+T S  
Sbjct: 900  GSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAE 959

Query: 1140 -THTLVCSKPPPDNIPPASSTHVISTTSTPEATQPISQVEETSTYALSFPYTFSGGGVVA 1198
             + T   +    +    +++    +T ST  +    + +E + T  +S   T S    V+
Sbjct: 960  GSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVS--STGSETTTVS 1017

Query: 1199 SLATGTTETSVVDETTPSHISANKLTTSVNSHISSSATYRVH----TPVSIQLVTSTSVL 1254
            +  T TT TS     T +  +A   TT+V +  S + T        T VS     +T+  
Sbjct: 1018 TTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAS 1077

Query: 1255 SSDKDQMTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHS 1314
            ++D +  T+S   +  T   T  S +   +I+ S+ T +     T   E T +S+     
Sbjct: 1078 TADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTA----STEGSEATTVST----- 1128

Query: 1315 PSEIPLGTPSDGNLASSPTSGSTQITPTLTSSNTVGVHIPEMSTSLGKTALPSQALTITT 1374
                   T S+   AS+  S  T +  T++ + TV     E +TS   +A  S+A T +T
Sbjct: 1129 -------TSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTS---SAAGSEATTTST 1178

Query: 1375 FLCPEKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINT 1434
                  E+T+A  A +  T      S   T S S  +  +   T + +ST  S   + NT
Sbjct: 1179 ---EGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNT 1235

Query: 1435 TFSHLHSLRTQPEVTSVASFISESTQTFPESLSLSTAGLYNDGFTVLSDRITTAFSVPNV 1494
             F     + ++  + S AS   E T T       +T  +   G T  S   TT  S   V
Sbjct: 1236 AF----IIGSESTIASTASL--EPTATSLTGSETTTVSITASGATAAS---TTVSSTTFV 1286

Query: 1495 PTMLPRESSMATSTPIYQMSSLPVNVTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTA 1554
             T        AT   I  +++ P++ T  T  +++         SS TM PG        
Sbjct: 1287 LT-------KATDVSIQPITNTPMSGTRTTGTRLT-------ASSSVTMAPGM----DFT 1328

Query: 1555 TSGPMSEMSSIPVNNSAFTPATVSSDTSTRVGLFSTLLSSVTPRTTMTMQTSTLDVTPVI 1614
             S     +  I +N S    +T+ + ++T      T   S    T+ T Q    +  PV 
Sbjct: 1329 ASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPTSSTFQ----ETGPVS 1384

Query: 1615 YAGATSKNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGT 1674
                T     VS + T   +     I P+ +L P    L  +  V   +   +   F   
Sbjct: 1385 MGTNT-----VSMSHTPTNV-----IKPSGYLQPWAIILISLAAVVAAVGLSVGLSFCLR 1434

Query: 1675 TAFSPL 1680
              F PL
Sbjct: 1435 NLFFPL 1440



 Score =  190 bits (483), Expect = 2e-47
 Identities = 344/1546 (22%), Positives = 588/1546 (38%), Gaps = 183/1546 (11%)

Query: 249  MTTPSQITGVKPQNTAHSSTLLSQSIPIF--ATDYTTISYSNT-TSPPLETMTAQKILKT 305
            M++ + +      NT  +ST  S++  I   A++ TT S + + T+ P  T +   I+  
Sbjct: 1    MSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSI 60

Query: 306  LVDETATFAVDVLSTSSAISLPTQSISIDNTTNSMKKTKSPSSESTKTTKMVEAMATEIF 365
               E  T      ST+ + +    S     TT SM       SE+T +T   E     I 
Sbjct: 61   SGSEITT-----TSTAGSENTTVSSAGSGTTTASMA-----GSETTVSTAGSETTTVSIT 110

Query: 366  QPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFSTIESTSMSTTPCLKQKSTNT 425
               T       S  T NS  S+ + + S +    TT      E+T+  T       ++ T
Sbjct: 111  GTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTT 170

Query: 426  GA--LPISTAGQEFIESTAAGTVPWFTVEKTSPASTHVGTASSFPPEPVLISTAAPVDSV 483
            G+    + TAG E I  + AG+         S A +   T S+   E    STA      
Sbjct: 171  GSEMTTVFTAGSETITPSTAGS----ETTTVSTAGSETTTVSTTGSETTTASTA------ 220

Query: 484  FPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETTPAPRTAETELTSTNFQDVSLPRVEDA 543
                  A  + +   K++      T+ T   ETT     A TE + TN       +   A
Sbjct: 221  HSETTAASTMGSETTKVSTAGSETTVSTAGSETT----AASTEDSETNTAFTEDSKTTTA 276

Query: 544  MSTSMSKETSSKTFSFLTSFSFTGTE-SVQTVIDAEATR--TALTPEITLASTVAETMLS 600
             +T      +S T S  T  S  G+E ++ + I  E T+  TA +   T+ +  +ET+ +
Sbjct: 277  STTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRA 336

Query: 601  STITGRVYTQNTPTADGHLLTLMSTRSASTSKAPESGPTSTTDEAAHLFSSNE-----TI 655
            ST+     T +T  ++    ++M + +++ S       T++T+ +    +S E     T+
Sbjct: 337  STVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTV 396

Query: 656  WTSRPDQALLASMNTTTILTFVPNENFTSAFHENTTYTEYLSATTNITPLKASPEGKGTT 715
             T+  +   ++  ++ T  T       T+    +TT  E  +A+T  + +  +      T
Sbjct: 397  STTGSETTTVSITDSETTTTCTEGSEMTAV---STTVFETTTASTEGSEITIASTSDSET 453

Query: 716  ANDATTARYTTAVSKLTSPWFANFSIVSGTTSITNMPEFKLTTLLLKTIPMSTKPANELP 775
               +T    TT V+   S     ++  S TT+ +N     L T  + TI   T  A+   
Sbjct: 454  TTASTEGSETTTVTTAGSETKTAYTTGSETTTASNT---GLETTTVFTIGSDTTTASTEG 510

Query: 776  LTPRETVVPSVDIISTLACIQPNFSTEESASETTQTEINGAIVFGGTTTPVPKSATTQRL 835
                       ++ +       N +   + SETT     G      TTT    S  T   
Sbjct: 511  SETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG---LETTTTSTEGSEMT--- 564

Query: 836  NATVTRKEATSHYLMRKSTIAAVAEVSPFSTMLEVTDESAQRVTA-SVTVSSFPDIEKLS 894
              + T  E T+       T AA    S  +T+     E+    TA S T S+     + +
Sbjct: 565  TVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETT 624

Query: 895  TPLDNKTATTEVRESWLLTKLVKTTPRSSYNEMTEMFNFNHTYVAHWTSETSEGISAGSP 954
            T     + TT        T  V TT   S   M        T  +   SET+   + GS 
Sbjct: 625  TASTTSSETTTASTEGSETTTVSTT--DSETTMVSTTGSERTITSTEGSETTTVSATGSE 682

Query: 955  TSGSTHIFGEPLGASTTRISETSFSTTPTDRTATSLSDGILPPQPTAAHSSATPVPVTHM 1014
            T+ ST       G+ TT +S T   TT    T +         + T   +  + +    +
Sbjct: 683  TTVSTE------GSGTTTVSITGSETTKVSTTGS---------ETTTTSTEGSEITTASI 727

Query: 1015 FSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVPPLDQTASTT 1074
                   +S    ET    +E S    A +T   +  ++ +S+  T A +   + T ++T
Sbjct: 728  TGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAST 787

Query: 1075 IVIVPTHGDLIRTTSEATVISVRKTSMAVPSLTETPFHSLRLSTPVTAKAETTLFSTSVD 1134
            I             SE T +S                 S +++T  T  +ETT+ ST+  
Sbjct: 788  I------------GSETTKVSTA---------------SSKMTTVFTENSETTIASTT-- 818

Query: 1135 TVTPSTHTLVCSKPPPDNIPPA---SSTHVISTTSTPEATQPISQVEETSTYALSFPYTF 1191
                ++ T   S    + IP +   S T   ++T   E T   ++  ET+T +     T 
Sbjct: 819  ----ASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETT 874

Query: 1192 SGGGVVASLATGTTETSVVDETTPSHISANKLTT--SVNSHISSSATYRVHTPVSIQLVT 1249
            +   + +   T +TE S   ETT +    ++ TT  +  S I++ +T    T  +    +
Sbjct: 875  TATTIGSETTTASTEGS---ETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGS 931

Query: 1250 STSVLSSDKDQMTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISS 1309
             T+  S++  ++T        T+  T              G+ ++ ++  G  ETT +  
Sbjct: 932  ETTTASTEGSELT--------TVSTT--------------GSETITVSAEG-SETTTV-- 966

Query: 1310 HQTHSPSEIPLGTPSDGNLASSPTSGSTQITPTLTSSNTVGVHIPEMSTSLGKTALPSQA 1369
              T   SE    + +     +  T+GS   T ++  S T  V     S++  +T   S  
Sbjct: 967  --TTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTV-----SSTGSETTTVSTT 1019

Query: 1370 LTITTFLCPEKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSSTRISNP 1429
             T TT    E   T+ +      T  +    +  T + + G +T+ V TT S +T  S  
Sbjct: 1020 GTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST- 1078

Query: 1430 MDINTTFSHLHSLRTQPEVTSVASFISESTQTF----PESLSLSTAGLYNDGFTVLSDRI 1485
             D+ TT     ++ T    T+ AS     T T      ++ + ST G      +  S   
Sbjct: 1079 ADLETT-----TVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSET 1133

Query: 1486 TTAFS----VPNVPTMLPRESSMATSTPIYQMSSLPVNVTAFTSKKVSDTPPIVITKSSK 1541
            TTA +    +  V T +   ++++T       SS   +    TS + S+T       S  
Sbjct: 1134 TTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSET 1193

Query: 1542 TMHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPATVSSDTSTR--VGLFSTLLSSVTPRT 1599
            T          TA++      ++    +   TP++  S+T+T   +G  ST+ S+ +   
Sbjct: 1194 TTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEP 1253

Query: 1600 TMTMQTSTLDVTPVIYA-GATSKNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTLPFVKT 1658
            T T  T +   T  I A GAT+ +  VSS               TTF+  T+ T   ++ 
Sbjct: 1254 TATSLTGSETTTVSITASGATAASTTVSS---------------TTFVL-TKATDVSIQP 1297

Query: 1659 VPTTIMAGIVTPFVGTTAFSPLSS------KSTGAISSIPKTTF--SPFLSATQQSSQAD 1710
            +  T M+G  T     TA S ++        ++ A  ++P      S   ++T  +S   
Sbjct: 1298 ITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTT 1357

Query: 1711 EATTLGILSGITNRSLSTVNSGTGVAL--TDTYSRITVPENMLSPT 1754
             A  +   +G T    S+    TG     T+T S    P N++ P+
Sbjct: 1358 SAHGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNVIKPS 1403



 Score =  186 bits (471), Expect = 4e-46
 Identities = 344/1489 (23%), Positives = 577/1489 (38%), Gaps = 190/1489 (12%)

Query: 548  MSKETS--SKTFSFLTSFSFTGTESVQTVIDAEATRTALTPEITLASTVAETMLSSTITG 605
            MS ET+      S  T+ S TG+E+   +I A  T TA T         +ET        
Sbjct: 1    MSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAG-------SET-------- 45

Query: 606  RVYTQNTPTADGHLLTLMSTRSASTSKAPESGPTSTTDEAAHLFSSNETIWTSRPDQALL 665
                  TP+  G   T++S   +  +    +G  +TT  +A   ++  ++  S    +  
Sbjct: 46   -----TTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTA 100

Query: 666  ASMNTTTILTFVPNENFTSAFHENTTYTEYLSATTNITPLKASPEGKGTTANDATTARYT 725
             S  TT  +T        SA    TT     S+ T +T    S     +T    TT  Y 
Sbjct: 101  GSETTTVSITGT-ETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAY- 158

Query: 726  TAVSKLTSPWFANFSIVSGTTSITNMPEFKLTTLLLKTIPMSTKPANELPLTPRETVVPS 785
            TA S+ T+             S T      + T   +TI  ST  +     T   T    
Sbjct: 159  TADSETTA------------ASTTGSEMTTVFTAGSETITPSTAGSE---TTTVSTAGSE 203

Query: 786  VDIISTLACIQPNFSTEESASETTQTEINGAIVFGGTTTPVPKSATTQRLNATVTRKEAT 845
               +ST         +E + + T  +E   A   G  TT V             T    T
Sbjct: 204  TTTVSTT-------GSETTTASTAHSETTAASTMGSETTKVS------------TAGSET 244

Query: 846  SHYLMRKSTIAAVAEVSPFSTMLEVTDESAQRVTASVTVSSFPDIEKLSTPLDNKTATTE 905
            +       T AA  E S  +T      E ++  TAS T   F      +T  +   A+T 
Sbjct: 245  TVSTAGSETTAASTEDSETNTAF---TEDSKTTTASTT--GFETTAASTTGSEPTMASTM 299

Query: 906  VRESWLLTKLVKTTPR--SSYNEMTEMFNFNHTYVAHWT--SETSEGISAGSPTSGSTHI 961
              E+ + + +   T +  ++ +E+T +F      +   T  SET+   + GS T+ +  I
Sbjct: 300  GSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETT-TASI 358

Query: 962  FGEPLGASTTRISETSFSTTPTDRTATSLSDGILPPQPTAAHSSATPVPVTHMFSLPVNG 1021
             G      +T  SET+ ++T    T T+ ++G          S AT V  T   +  V  
Sbjct: 359  MGSETSTDSTTGSETTTASTEGSETTTASTEG----------SEATTVSTTGSETTTV-- 406

Query: 1022 SSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVPPLDQTASTTIVIVPTH 1081
             S+   ET  T +E S +  A ST+V       ++T  T      +  T+ +      T 
Sbjct: 407  -SITDSETTTTCTEGSEMT-AVSTTVFE-----TTTASTEGSEITIASTSDSETTTASTE 459

Query: 1082 GDLIRTTSEATVISVRKTSMAVPSLTETPFHS-LRLSTPVTAKAETTLFS-----TSVDT 1135
            G    TT+  T  S  KT+    S T T  ++ L  +T  T  ++TT  S     T+  +
Sbjct: 460  GS--ETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVS 517

Query: 1136 VTPSTHTLVCSKPPPDNI--PPASSTHVISTT---STPEATQPISQVEETSTYALSFPYT 1190
             T S  T V ++   +       S T  +STT   +T  +T+       ++T A +   +
Sbjct: 518  ATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDS 577

Query: 1191 FSGGGVVASLATG--TTETSVVDETTPSHISANKLTTSVNS----HISSSATYRVHTPVS 1244
              G G  A+   G  TT  S  D    +  +A+  TTS ++      ++S T    T  S
Sbjct: 578  TEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTAS 637

Query: 1245 IQLVTSTSVLSSDKDQMTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGF--- 1301
             +   +T+V ++D +   +S   + RT+  TE S +     + S  T S E + T     
Sbjct: 638  TEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSI 697

Query: 1302 --PETTKISSHQTHSP------SEIPLGTPSDGNLASSPTSGSTQITPT-----LTSSNT 1348
               ETTK+S+  + +       SEI   + +     ++ T GS   T +      TS++T
Sbjct: 698  TGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSAST 757

Query: 1349 VGVHIPEMSTSLGKTALPSQALTITTFLCPEKESTSALPAYTPRTVEMIVNSTYVTHSVS 1408
             G      ST+  +T + S   + TT        T+ +   + +   +   ++  T + +
Sbjct: 758  TGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 817

Query: 1409 YGQDTSFV---------------DTTTSSSTRISNPMDINTTFSHLHSLRTQPEVTSVAS 1453
               +T+ V               +TTT++ST  S     +T  S   +  T+   T+ A+
Sbjct: 818  TASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT 877

Query: 1454 FISESTQTF----PESLSLSTAGLYNDGFTVLSDRITTAFSVPNVPTMLPRESSMATSTP 1509
             I   T T      E+ + ST G      +     ITT  +  +  T    E S  T+  
Sbjct: 878  TIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 937

Query: 1510 IYQMSSLPVNVTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTATSGPMSEMSSIPVNN 1569
                    V+ T   +  VS        + S+T     + S  T  S   SE +++    
Sbjct: 938  TEGSELTTVSTTGSETITVS-------AEGSETTTVTTMGSETTTASTAGSETTTVSTAG 990

Query: 1570 SAFTPATVSSDTSTRV---GLFSTLLSSVTPRTTMTMQTSTLDVTPVIYAGATSKNKMVS 1626
            S  T A++    +T V   G  +T +S+    TT+T  T   + T V  AG+ +     +
Sbjct: 991  SETTTASIEGSETTTVSSTGSETTTVSTTGTETTIT-STEGSETTTVTTAGSETTAVYTT 1049

Query: 1627 SAFTTEMIEAPSRITPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSPLSSKSTG 1686
             + TT      S  T T   + +E T      + TT ++   T   GTT  S   S++T 
Sbjct: 1050 GSETTTTSTEGSE-TTTVSTTGSETTTASTADLETTTVS---TSGSGTTTASTAGSETTT 1105

Query: 1687 AISSIPKTTFSPFLSATQQSSQADEATTLGILSGITNRSLSTVNSGTGV--ALTDTYSRI 1744
               +  KTT +        S++  EATT+   S  T  + +T +  T V   +++T +  
Sbjct: 1106 VYITGSKTTTA--------STEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVS 1157

Query: 1745 TVPENMLSPTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLLEK 1804
            T+     + + A S  T+ + + S + T+  + S  T    T +   S  T   TS  E 
Sbjct: 1158 TIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETT----TASTAGSETTTASTSGSET 1213

Query: 1805 TSLTNYATSLNTPVSYPPWT------------PSSATL-PSLTSFVYSPHSTEAEISTPK 1851
             +     +  +TP S    T             S+A+L P+ TS   S  +T +  ++  
Sbjct: 1214 NTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGSETTTVSITASGA 1273

Query: 1852 TSPPPTSQMVEFPVLGTRMTSSNTQPLLMTSWNIPTAEGSQFPISTTINV-PTSNEMETE 1910
            T+   T     F +  T+ T  + QP+  T  +     G++   S+++ + P  +   + 
Sbjct: 1274 TAASTTVSSTTFVL--TKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASA 1331

Query: 1911 TLHLVPGPLSTFTASQTGLVSKDVMAMSSIPMSGILPNHGLSENPSLST 1959
              H VPG       + +GL +  + A S+    G+    G +  P+ ST
Sbjct: 1332 ASHTVPG----IVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPTSST 1376



 Score =  167 bits (422), Expect = 2e-40
 Identities = 290/1321 (21%), Positives = 523/1321 (39%), Gaps = 194/1321 (14%)

Query: 953  SPTSGSTHIFGEPLGASTTRISETSFSTTPTDRTATSLSDGILPPQPTAAHSSATPVPVT 1012
            +P +GS        G+ TT I   +  TT    TA++       P PT + ++       
Sbjct: 8    APAAGSNTTTASTTGSETTTILIKASETT----TASTAGSETTTPSPTGSQTTI------ 57

Query: 1013 HMFSLPVNGSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVPPLDQTAS 1072
                + ++GS +    T    SE +T++ A S +  + ++  S TT++TA       + +
Sbjct: 58   ----VSISGSEITT--TSTAGSENTTVSSAGSGTTTASMAG-SETTVSTA------GSET 104

Query: 1073 TTIVIVPTHGDLIR-----------TTSEATVISVR----KTSMAVPSLTETPF--HSLR 1115
            TT+ I  T   ++            T+SE TV S       T   V S T T +   S  
Sbjct: 105  TTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSET 164

Query: 1116 LSTPVTAKAETTLFSTSVDTVTPSTHTLVCSKPPPDNIPPASSTHVISTTSTPEATQPIS 1175
             +   T    TT+F+   +T+TPST                S T  +STT +   T   +
Sbjct: 165  TAASTTGSEMTTVFTAGSETITPST----AGSETTTVSTAGSETTTVSTTGSETTTASTA 220

Query: 1176 QVEETSTYALSFPYTFSGGGVVASLATGTTETSVVDETTPSHISANKLTTSV--NSHISS 1233
              E T+   +    T      V++  + TT ++   ETT +    ++  T+   +S  ++
Sbjct: 221  HSETTAASTMGSETT-----KVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTT 275

Query: 1234 SATYRVHTPVSIQLVTSTSVLSSDKDQMTISLGKTPRTMEVTEMSPSKNSFISYSRGTPS 1293
            ++T    T  +    +  ++ S+   + T++    P T +V+  S    +   ++ G+ +
Sbjct: 276  ASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTV--FAAGSET 333

Query: 1294 LEMTDTGFPETTKISSHQTHSPSEIPLG--TPSDGNLASSPTSGSTQITPTLTSSNTVGV 1351
            +  +  G  ETT +S+  + + +   +G  T +D    S  T+ ST+ + T T+S T G 
Sbjct: 334  IRASTVG-SETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTAS-TEGS 391

Query: 1352 HIPEMSTSLGKTALPSQALTITTFLCPEKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQ 1411
                +ST+  +T   S   + TT  C E    +A+      T          T + + G 
Sbjct: 392  EATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFET----------TTASTEGS 441

Query: 1412 DTSFVDTTTSSSTRISNPMDINTTFSHLHSLRTQPEVTSVASFISESTQTFPESLSLSTA 1471
            + +   T+ S +T  S      TT            VT+  S    +  T  E+ + S  
Sbjct: 442  EITIASTSDSETTTASTEGSETTT------------VTTAGSETKTAYTTGSETTTASNT 489

Query: 1472 GLYNDGFTVLSDRITTAFSVPNVPTMLPRESSMATSTPIYQMSSLPVNVTAFTSKKVSDT 1531
            GL            TT F++ +  T    E S  T+     +S+    +T  +++   +T
Sbjct: 490  GL----------ETTTVFTIGSDTTTASTEGSETTA-----VSATGSEMTTVSTEGSENT 534

Query: 1532 PPIVITKSSKTMHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPATVSSDTSTRVGLFSTL 1591
                    + T+    L++  T+T G  SEM+++    +  T  +     +T      + 
Sbjct: 535  TVSTTGSETTTVSTTGLETTTTSTEG--SEMTTVSTTGAETTTDSTEGSGTTAASTAGSE 592

Query: 1592 LSSVTPRTTMTMQTSTLDVTPVIYAGATSKNKMVSSAFTTEMIEAPSRITPTTFLSPTEP 1651
             ++V+   +     ST D +    A  T      +S  ++E   A +  + TT +S T+ 
Sbjct: 593  TTTVSTADSENTTASTAD-SETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDS 651

Query: 1652 TLPFVKTVPTTIMAGIVTPFVGTTAFSPLSSKSTGAISSIPKTTFSPFLSATQQSSQADE 1711
                             T  V TT     S ++  +      TT S   S T  S++   
Sbjct: 652  E----------------TTMVSTTG----SERTITSTEGSETTTVSATGSETTVSTEGSG 691

Query: 1712 ATTLGILSGITNRSLSTVNSGTGVALTD----TYSRITVPENMLSPTHADSLHTSFNIQV 1767
             TT+ I    T + +ST  S T    T+    T + IT  E   + T      T+     
Sbjct: 692  TTTVSITGSETTK-VSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA----- 745

Query: 1768 SPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLL-EKTSLTNYATSLNTPVSYPPWTPS 1826
              S    ++ S  T   +TTT   +S+   M S++  +T++ +   S  T VS       
Sbjct: 746  --STEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVS------- 796

Query: 1827 SATLPSLTSFVYSPHSTEAEISTPKTSPPPTSQMVEFPVLGTRMTSSNTQPLLMTSWNIP 1886
            +A+    T F  +  +T A  +  +T+   T+     P       ++ T     +     
Sbjct: 797  TASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTA 856

Query: 1887 TAEGSQFPISTTINVPTSNEMETETLHLVPGPLSTFTASQTGLVSKDVMAMSSIPMSGIL 1946
            + EGS+    TT     S+E  T T        ++   S+T   S +    ++    G  
Sbjct: 857  STEGSE----TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEG-- 910

Query: 1947 PNHGLSENPSLSTSLRAITSTLADVKHTFEKMTTSVTPGTTLPSILSGATSGSVISKSPI 2006
                 SE  ++ST+    T+   +   T    TT+ T G+ L ++ +  +    +S    
Sbjct: 911  -----SEITTVSTTGSETTTASTEGSET----TTASTEGSELTTVSTTGSETITVSAEGS 961

Query: 2007 LTWLLSSLPS--------GSPPATVSNAPHVMTSSTVEVSKSTFLTSDMISAHPFTNLTT 2058
             T  ++++ S        GS   TVS A    T++++E S++T ++S           T 
Sbjct: 962  ETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSS-----------TG 1010

Query: 2059 LPSATMSTILTRTIPTPTLGGITTGFPTSLPMSINVTDDIVYISTHPEASSRTTITANPR 2118
              + T+ST  T T  T T G  TT   T+       ++     +T  E ++ +T  +   
Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTA------GSETTAVYTTGSETTTTSTEGSETT 1064

Query: 2119 TVSHPSSFSRKTMSPSTTDHTLSVGAMPLPSSTITSSWNRIPTASSPSTLIIPKPTLDSL 2178
            TVS   S   +T + ST D         L ++T+++S +   TAS+  +    + T   +
Sbjct: 1065 TVSTTGS---ETTTASTAD---------LETTTVSTSGSGTTTASTAGS----ETTTVYI 1108

Query: 2179 LNIMTTTSTVPGASFPLISTGVTYPFTA-TVSSPISSFFETTWLDSTPSFLSTEASTSPT 2237
                TTT++  G+    +ST  +   TA T  S +++ F T    +T S + +EA+TS  
Sbjct: 1109 TGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSA 1168

Query: 2238 A 2238
            A
Sbjct: 1169 A 1169



 Score =  164 bits (415), Expect = 1e-39
 Identities = 327/1450 (22%), Positives = 566/1450 (39%), Gaps = 155/1450 (10%)

Query: 852  KSTIAAVAEVSPFSTMLEVTDESAQRVTASVTVSSFPDIEKLSTPLDNKTATTEVRESWL 911
            ++T+A  A  +  +     ++ +   + AS T ++     + +TP    + TT V  S  
Sbjct: 4    ETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISG- 62

Query: 912  LTKLVKTTPRSSYNEMTEMFNFNHTYVAHWTSETSEGISAGSPTS-----GSTHIFGEPL 966
             +++  T+   S N          T  +   SET+   +AGS T+     G+       +
Sbjct: 63   -SEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVS-TAGSETTTVSITGTETTMVSAM 120

Query: 967  GASTTRISETSFSTTPTD----RTATSLSDGILPPQPTAAHSSATPVPVT--HMFSLPVN 1020
            G+ TT  S TS  TT T      T T  + G        A S  T    T   M ++   
Sbjct: 121  GSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180

Query: 1021 GSSVVAEETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVPPLDQTASTTIVIVPT 1080
            GS  +   T    SE +T++ A S +     +   +TT +TA     + TA++T+    T
Sbjct: 181  GSETITPST--AGSETTTVSTAGSETTTVSTTGSETTTASTA---HSETTAASTMGSETT 235

Query: 1081 HGDLIRTTSEATVISVRKTSMAVPSLTETPFHSLRLSTPVTAKAETTLFSTSVDTVTPST 1140
                + T    T +S   +     S  ++  ++       T  A TT F T+  + T S 
Sbjct: 236  K---VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSE 292

Query: 1141 HTLVCSKPPPDNIPPASSTHVISTTSTPEATQPISQVEETSTYALSFPYTFSGGGVVASL 1200
             T+  +           S   +++T  PE T+  +   E +T        F+ G      
Sbjct: 293  PTMASTM---------GSETTMASTIGPETTKVSTASSEVTT-------VFAAGSETIRA 336

Query: 1201 ATGTTETSVVD----ETTPSHISANKLTT--SVNSHISSSATYRVHTPV-SIQLVTSTSV 1253
            +T  +ET+ V     ETT + I  ++ +T  +  S  ++++T    T   S +   +T+V
Sbjct: 337  STVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTV 396

Query: 1254 LSSDKDQMTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTH 1313
             ++  +  T+S+  +  T   TE             G+    ++ T F ETT  S+    
Sbjct: 397  STTGSETTTVSITDSETTTTCTE-------------GSEMTAVSTTVF-ETTTASTEG-- 440

Query: 1314 SPSEIPLGTPSDGNLASSPTSGSTQITPTLTSSNTVGVHIP-EMSTSLGKTALPSQAL-- 1370
              SEI + + SD    ++ T GS   T T   S T   +     +T+   T L +  +  
Sbjct: 441  --SEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFT 498

Query: 1371 --TITTFLCPEKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTT----TSSST 1424
              + TT    E   T+A+ A       +    +  T   + G +T+ V TT    T++ST
Sbjct: 499  IGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTST 558

Query: 1425 RISNPMDINTTFSHLHSLRTQPEVTSVASFISESTQTFP----ESLSLSTAGLYNDGFTV 1480
              S    ++TT +   +  T+   T+ AS     T T      E+ + STA       + 
Sbjct: 559  EGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSAST 618

Query: 1481 LSDRITTAFSVPNVPTMLPRESSMATSTPIYQMSSLPVNVTA----FTSKKVSDTPPI-- 1534
                 TTA +  +  T    E S  T+       +  V+ T      TS + S+T  +  
Sbjct: 619  TGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSA 678

Query: 1535 ------VITKSSKTMHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPATVSSDTSTRVGLF 1588
                  V T+ S T       S  T  S   SE ++     S  T A+++   +T     
Sbjct: 679  TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTA--- 735

Query: 1589 STLLSSVTPRTTMTMQTSTLDVT--PVIYAGATSKNKMVSSAFTTEMIEAPSRITPTTFL 1646
            ST  S  T  +T   +T++   T      A  TS    ++S   +E   A +  + TT +
Sbjct: 736  STEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKV 795

Query: 1647 SPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSPLSSKSTGAISSIPKTTF---------- 1696
            S     +       TT+        + +T  S  ++ ST    +IP +T           
Sbjct: 796  STASSKM-------TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTST 848

Query: 1697 ------------SPFLSATQQSSQADEATTLG------ILSGITNRSLSTVNSGTGVALT 1738
                        S   +A+ +SS+   ATT+G         G    + ST  S T  A T
Sbjct: 849  EGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAST 908

Query: 1739 DTYSRITVPENMLSPTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKM 1798
            +  S IT      S T   S   S     S   +   + S  T +   T +   S T  +
Sbjct: 909  EG-SEITTVSTTGSETTTASTEGSETTTASTEGSELTTVS-TTGSETITVSAEGSETTTV 966

Query: 1799 TSLLEKTSLTNYATSLNTPVSYPPWTPSSATLP-SLTSFVYSPHSTEAEISTPKTSPPPT 1857
            T++  +T+  + A S  T VS      ++A++  S T+ V S  S    +ST  T    T
Sbjct: 967  TTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTIT 1026

Query: 1858 SQMVEFPVLGTRMTSSNTQPLLMTSWNIPTAEGSQFPISTTINVPTSNEMETETLHLVPG 1917
            S   E     T  T+ +    + T+ +  T   ++   +TT++   S      T  L   
Sbjct: 1027 S--TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT 1084

Query: 1918 PLSTFTASQTGLVSKDVMAMSSIPMSGILPNHGLSENPSLSTSLRAITSTLADVKHTFEK 1977
             +ST + S T   S      +++ ++G       +E  S +T++   +S       T  +
Sbjct: 1085 TVST-SGSGTTTASTAGSETTTVYITGSKTTTASTEG-SEATTVSTTSSETTTASTTGSE 1142

Query: 1978 MT---TSVTPGTTLPSILSGATSGSVISKSPILTWLLSSLPSGSPPATVSNAPHVMTSST 2034
            MT   T+V+  TT+ +I S AT+ S        T        GS   T S A    T+++
Sbjct: 1143 MTTVFTTVSETTTVSTIGSEATTSSAAGSEATTT-----STEGSETTTASTAGSETTTAS 1197

Query: 2035 VEVSKSTFLT---SDMISAHPFTNLTTLPSATMSTILTRTI--PTPTLGGITTGFPTSLP 2089
               S++T  +   S+  +A    + T+ PS+  S   T  I     T+    +  PT+  
Sbjct: 1198 TAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATS 1257

Query: 2090 MSINVTDDIVYISTHPEASSRTTITANPRTVSHPSSFSRKTMSPSTTDHTLSVGAMPLPS 2149
            ++ + T  +   ++   A+S TT+++    ++  +  S + ++ +    T + G     S
Sbjct: 1258 LTGSETTTVSITASGATAAS-TTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTAS 1316

Query: 2150 STITSSWNRIPTASSPSTLIIPKPTLDSLLNIMTTTSTVPGASFPLISTGVTYPFTATVS 2209
            S++T +     TAS+ S  +   P +  +LN     ++  GAS    + GV    T +  
Sbjct: 1317 SSVTMAPGMDFTASAASHTV---PGI--VLNTSGLGTSTMGASSTTSAHGVR-TTTGSTR 1370

Query: 2210 SPISSFFETT 2219
             P SS F+ T
Sbjct: 1371 EPTSSTFQET 1380



 Score =  147 bits (371), Expect = 2e-34
 Identities = 265/1153 (22%), Positives = 443/1153 (38%), Gaps = 135/1153 (11%)

Query: 1204 TTETSVVDETTPSHISANKLTTSVNSHISS---SATYRVHTPVSIQLVTSTSVLSSDKDQ 1260
            TT ++   ETT   I A++ TT+  +   +   S T    T VSI     T+  ++  + 
Sbjct: 16   TTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSEN 75

Query: 1261 MTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSPSEIPL 1320
             T+S   +  T     M+ S+ +  +    T ++ +T T   ETT +S+          +
Sbjct: 76   TTVSSAGSGTT--TASMAGSETTVSTAGSETTTVSITGT---ETTMVSA----------M 120

Query: 1321 GTPSDGNLASSPTSGSTQITPTLTSSNTVGVHIPEMSTSLGKTALPSQALTITTFLCPEK 1380
            G+ +  N   S TS  T +T T  S  T       +ST   +T         TT    + 
Sbjct: 121  GSETTTN---STTSSETTVTSTAGSETTT------VSTVGSET---------TTAYTADS 162

Query: 1381 ESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINTTFSHLH 1440
            E+T+A    +  T      S  +T S + G +T+ V T  S +T +S      TT S  H
Sbjct: 163  ETTAASTTGSEMTTVFTAGSETITPSTA-GSETTTVSTAGSETTTVSTTGSETTTASTAH 221

Query: 1441 SLRTQPEVTSVASFISESTQ--TFPESLSLSTAGLYNDGFTVLSDRITTAFSVPNVPTML 1498
            S     E T+ ++  SE+T+  T     ++STAG      +       TAF+        
Sbjct: 222  S-----ETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFT-------- 268

Query: 1499 PRESSMATSTPIYQMSSLPVNVTAFTSKKVSDT---PPIVITKSSKTMHPGCLKSPCTAT 1555
              E S  T+           + T F +   S T   P +  T  S+T     +    T  
Sbjct: 269  --EDSKTTTA----------STTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKV 316

Query: 1556 SGPMSEMSSI-PVNNSAFTPATVSSDTSTRVGLFSTLLSSVTPRTTMTMQTSTLDVTPVI 1614
            S   SE++++    +     +TV S+T+T     ST  S  T  + M  +TST   T   
Sbjct: 317  STASSEVTTVFAAGSETIRASTVGSETTT----VSTTGSETTTASIMGSETSTDSTT--- 369

Query: 1615 YAGATSKNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGT 1674
                T+      S  TT   E     T +T  S T           TT   G     V T
Sbjct: 370  -GSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVST 428

Query: 1675 TAFSPLSSKSTGAISSIPKTTFSPFLSATQQSSQADEATTLG--ILSGITNRSLSTVNSG 1732
            T F   ++ + G+  +I  T+ S   +A+ + S+    TT G    +  T  S +T  S 
Sbjct: 429  TVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASN 488

Query: 1733 TGVALTDTYSRITVPENMLSPTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFS 1792
            TG+  T  ++       + S T   S   S    VS + +   + S       T +   S
Sbjct: 489  TGLETTTVFT-------IGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGS 541

Query: 1793 SNTRKMTSLLEKTSLTNYATSLNTPVSYPPWTPSSATLPSLTSFVYSPHSTEAEISTPKT 1852
              T   T+ LE T+ +   + + T  +    T + +T  S T+   +  S    +ST   
Sbjct: 542  ETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTAD- 600

Query: 1853 SPPPTSQMVEFPVLGTRMTSSNTQPLLMTSWNIPTA--EGSQFPISTTINVPTSNEMETE 1910
            S   T+   +        T S T     TS    TA  EGS+    +T +  T+    T 
Sbjct: 601  SENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTG 660

Query: 1911 TLHLVPGP--LSTFTASQTG---LVSKDVMAMSSIPMSGILPNHGLSENPSLSTSLRAIT 1965
            +   +       T T S TG    VS +    +++ ++G       SE   +ST+    T
Sbjct: 661  SERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITG-------SETTKVSTTGSETT 713

Query: 1966 ST------LADVKHTFEKMTTSVTPGTTLPSILSGATSGSVISKSPILTWLLSSLPSGSP 2019
            +T      +     T  + TT+ T G+   +  +  +  +  S +   T   S+  S + 
Sbjct: 714  TTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETT 773

Query: 2020 PATVSNAPHVMTSST-VEVSKSTFLTSDMISAHPFTNLTTLPSAT------MSTILTRTI 2072
             A++  +   M S+   E +K +  +S M +     + TT+ S T      +ST  + TI
Sbjct: 774  MASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETI 833

Query: 2073 PTPTLGGITTGFPTSLPMSINVTDDIVYISTHPEASSRTTITANPRTVSHPSSFSRKTMS 2132
            P  T G  TT        +   T+     +   E S  TT +      +  ++   +T +
Sbjct: 834  PASTAGSETT--------TTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTT 885

Query: 2133 PSTT-DHTLSVGAMPLPSSTITSSWNRIPTASSPSTLIIPKPTLDSLLNIMTTTSTVPGA 2191
             ST    T +       ++T ++  + I T S+  +    + T  S     TTT++  G+
Sbjct: 886  ASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGS----ETTTASTEGSETTTASTEGS 941

Query: 2192 SFPLISTGVTYPFTATVSSPISSFFETTWLDSTPSFLSTEASTSPTATK--STVSFYNVE 2249
                +ST  T   T TVS+  S     T + S  +  ST  S + T +   S  +  ++E
Sbjct: 942  ELTTVST--TGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIE 999

Query: 2250 MSFSVFVEEPRIPITSVINEFTENSLNSIFQNSEFSLATLETQIKSRDISEEEMVMDRAI 2309
             S +  V       T+V    TE ++ S   +   ++ T  ++  +   +  E       
Sbjct: 1000 GSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSE-----TT 1054

Query: 2310 LEQREGQEMATIS 2322
                EG E  T+S
Sbjct: 1055 TTSTEGSETTTVS 1067



 Score =  145 bits (367), Expect = 5e-34
 Identities = 274/1150 (23%), Positives = 454/1150 (39%), Gaps = 122/1150 (10%)

Query: 1154 PPASSTHVISTTSTPEATQPISQVEETSTYALSFPYTFSGGGVVASLATGTTETSVVDET 1213
            P A S    ++T+  E T  + +  ET+T + +   T             TT +    +T
Sbjct: 9    PAAGSNTTTASTTGSETTTILIKASETTTASTAGSET-------------TTPSPTGSQT 55

Query: 1214 TPSHISANKLTT-----SVNSHISSSATYRVHTPVSIQLVTSTSVLSSDKDQMTISLGKT 1268
            T   IS +++TT     S N+ +SS+ +    T  +    + T+V ++  +  T+S+  T
Sbjct: 56   TIVSISGSEITTTSTAGSENTTVSSAGS---GTTTASMAGSETTVSTAGSETTTVSITGT 112

Query: 1269 PRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSP------SEIPLGT 1322
              TM     S +  +  + S  T    +T T   ETT +S+  + +       SE    +
Sbjct: 113  ETTMVSAMGSETTTNSTTSSETT----VTSTAGSETTTVSTVGSETTTAYTADSETTAAS 168

Query: 1323 PSDGNLASSPTSGSTQITPTLTSS-----NTVGVHIPEMSTSLGKTALPSQALTITTFLC 1377
             +   + +  T+GS  ITP+   S     +T G     +ST+  +T   S A + TT   
Sbjct: 169  TTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAAS 228

Query: 1378 PE-KESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDT------------TTSSST 1424
                E+T    A +  TV    + T    +     +T+F +             TT++ST
Sbjct: 229  TMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAST 288

Query: 1425 RISNPMDINTTFSHLHSLRT-QPEVTSVASFISESTQTFP---ESLSLSTAGLYNDGFTV 1480
              S P   +T  S      T  PE T V++  SE T  F    E++  ST G      + 
Sbjct: 289  TGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVST 348

Query: 1481 LSDRITTAFSVPNVPTMLPRESSMATSTPIYQMSSLPVNVTAFTSKKVSDTPPIVITKSS 1540
                 TTA S+    T     +   T+T   + S      TA T    + T   V T  S
Sbjct: 349  TGSETTTA-SIMGSETSTDSTTGSETTTASTEGSE---TTTASTEGSEATT---VSTTGS 401

Query: 1541 KTMHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPATVSSDTSTRVGLFSTLLSSVTPRTT 1600
            +T       S  T T    SEM++  V+ + F   T S++ S         ++S +   T
Sbjct: 402  ETTTVSITDSETTTTCTEGSEMTA--VSTTVFETTTASTEGS------EITIASTSDSET 453

Query: 1601 MTMQTSTLDVTPVIYAGATSKNKMVSSAFTTEMIEAPSRITPTTFLSPTEPTLPFVKTVP 1660
             T  T   + T V  AG+ +K    + + TT         T T F   ++ T    +   
Sbjct: 454  TTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT-TVFTIGSDTTTASTEGSE 512

Query: 1661 TTIMAGIVTPFVGTTAFSPLSSKSTGAISSIPKTTFSPF-LSATQQSSQADEATTLGILS 1719
            TT ++   +    TT  +  S  +T + +    TT S   L  T  S++  E TT+   +
Sbjct: 513  TTAVSATGSEM--TTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVST-T 569

Query: 1720 GITNRSLSTVNSGTGVALTDTYSRITVP----ENMLSPTHADSLHTSFNIQVSP----SL 1771
            G    + ST  SGT  A T      TV     EN  + T ADS  TS +   S     S 
Sbjct: 570  GAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAST-ADSETTSASTTGSETTTAST 628

Query: 1772 TSFKSASGPTKNVKTTT-NCFSSNTRKMTSLLEKTSLTNYATSLNTPVSYPPWTPSSATL 1830
            TS ++ +  T+  +TTT +   S T  +++   + ++T+   S  T VS      + +T 
Sbjct: 629  TSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTE 688

Query: 1831 PSLTSFVYSPHSTEAEISTPKTSPPPTS----QMVEFPVLGTRMTSSNTQPLLMTSWNIP 1886
             S T+ V    S   ++ST  +    TS    ++    + G+  T+++T+    T+    
Sbjct: 689  GSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT---A 745

Query: 1887 TAEGSQFPISTTINVPTSNEMETETLHLVPGPLSTFTASQTGLVSKDVMAMSSIPMSGIL 1946
            + EGS+    TT    T +E  T +       +++   S+T + S      + +  +   
Sbjct: 746  STEGSE----TTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSK 801

Query: 1947 PNHGLSENPSLSTSLRAITSTLADVKHTFEKMTTSVTPGTTLPSILSGATSGSVISKSPI 2006
                 +EN     S   I ST A      E  T S     T+P+  +G+ + +  S    
Sbjct: 802  MTTVFTEN-----SETTIASTTAS-----ETTTVSTAGSETIPASTAGSETTTTTSTEGS 851

Query: 2007 LTWLLSSLPSGSPPATVSNAPHVMTSSTVEVSKSTFLT---SDMISAHPFTNLTTLPSA- 2062
             T   S+   GS   T S      T++T   S++T  +   S+  +     + TT  S  
Sbjct: 852  ETTTAST--EGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTE 909

Query: 2063 -----TMSTILTRTIPTPTLGGITTGFPTSLPMSINV-TDDIVYISTHPEASSRTTITAN 2116
                 T+ST  + T    T G  TT   T       V T     I+   E S  TT+T  
Sbjct: 910  GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTM 969

Query: 2117 PRTVSHPSSFSRKTMSPSTT-DHTLSVGAMPLPSSTITSSWNRIPTASSPSTLIIPKPTL 2175
                +  S+   +T + ST    T +       ++T++S+ +   T S+  T    + T+
Sbjct: 970  GSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGT----ETTI 1025

Query: 2176 DSLLNIMTTTSTVPGASFPLI-STGVTYPFTATVSSPISSFFETTWLDSTPSFLSTEAST 2234
             S     TTT T  G+    + +TG     T+T  S  ++   T    +T S    E +T
Sbjct: 1026 TSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTT 1085

Query: 2235 SPTATKSTVS 2244
              T+   T +
Sbjct: 1086 VSTSGSGTTT 1095



 Score = 88.6 bits (218), Expect = 9e-17
 Identities = 148/643 (23%), Positives = 236/643 (36%), Gaps = 78/643 (12%)

Query: 219  IPTVDRTLRCFVPENMTIQEKSTTVSQQIDMTTPSQITGVKPQNTAHSSTLLSQSIPIFA 278
            + T    +     EN      STT S+   ++T    T   P +TA S T  + S     
Sbjct: 795  VSTASSKMTTVFTENSETTIASTTASETTTVSTAGSET--IPASTAGSETTTTTSTEGSE 852

Query: 279  TDYTTISYSNTTSPPL---ETMTAQKI------LKTLVDETATFAVDVLSTSSAISLPTQ 329
            T   +   S TT+      ET TA  I        T   ET T + +   T++A    T+
Sbjct: 853  TTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTA---STE 909

Query: 330  SISIDNTTNSMKKTKSPSSESTKTTKMVEAMATEIFQPPTPSNFLSTSRFTKNSVVSTTS 389
               I   + +  +T + S+E ++TT      +TE  +  T S        T  S   T S
Sbjct: 910  GSEITTVSTTGSETTTASTEGSETT----TASTEGSELTTVS--------TTGSETITVS 957

Query: 390  AIKSQSAVTKTTSLFSTIESTSMSTTPCLKQKSTNTGALPISTAGQEFIESTAAGTVPWF 449
            A  S++    T    +T  ST+ S T              +STAG E   ++  G+    
Sbjct: 958  AEGSETTTVTTMGSETTTASTAGSET------------TTVSTAGSETTTASIEGS-ETT 1004

Query: 450  TVEKTSPASTHVGTASSFPPEPVLISTAAPVDSVFPRNQTAFPLATTDMKIAFTVHSLTL 509
            TV  T   +T V T            T   + S      T    A ++    +T  S T 
Sbjct: 1005 TVSSTGSETTTVSTT----------GTETTITSTEGSETTTVTTAGSETTAVYTTGSET- 1053

Query: 510  PTRLIETTPAPRTAETELTSTNFQDVSLPRVEDAMSTSMSKETSSKTFSFLTSFSFTGTE 569
                  TT +   +ET   ST   + +     D  +T++S   S       T+ S  G+E
Sbjct: 1054 ------TTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG-----TTTASTAGSE 1102

Query: 570  SVQTVIDAEATRTALTPEITLASTVAETMLSSTITGRVYTQNTPTADGHLLTLMSTRSAS 629
            +    I    T TA T E + A+TV+ T   +T         T +  G  +T + T  + 
Sbjct: 1103 TTTVYITGSKTTTAST-EGSEATTVSTTSSETT---------TASTTGSEMTTVFTTVSE 1152

Query: 630  TSKAPESGPTSTTDEAAHLFSSNETIWTSRPDQALLASMNTTTILTFVPNENFTSAFHEN 689
            T+     G  +TT  AA   ++  +   S    A  A   TTT  T   +E  T++   +
Sbjct: 1153 TTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTAST-AGSETTTASTSGS 1211

Query: 690  TTYTEYLSATTNITPLKASPEGK-----GTTANDATTARYTTAVSKLTSPWFANFSIVSG 744
             T T   + +   TP  A  E       G+ +  A+TA      + LT       SI + 
Sbjct: 1212 ETNTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGSETTTVSITAS 1271

Query: 745  TTSITNMPEFKLTTLLLKTIPMSTKPANELPLTPRETVVPSVDIISTLACIQPNFSTEES 804
              +  +      T +L K   +S +P    P++   T    +   S++        T  +
Sbjct: 1272 GATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASA 1331

Query: 805  ASETTQTEINGAIVFGGTTTPVPKSATTQRLNATV-TRKEATS 846
            AS T    +      G +T     + +   +  T  + +E TS
Sbjct: 1332 ASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPTS 1374


>gi|229093087 G protein-coupled receptor 97 [Homo sapiens]
          Length = 549

 Score =  200 bits (509), Expect = 2e-50
 Identities = 133/406 (32%), Positives = 198/406 (48%), Gaps = 35/406 (8%)

Query: 2607 IYLPKSLTERIP----LSNLQTILFNFFGQTSLFKTKNV-----TKALTTYVVSASISDD 2657
            + LPKSL   +P    +  L   + +  G  +LFK   +     +  L   +V  S+   
Sbjct: 131  VRLPKSLFRSLPGNRSVVRLAVTILDI-GPGTLFKGPRLGLGDGSGVLNNRLVGLSVGQ- 188

Query: 2658 MFIQNLADPVVITLQHIGGNQNYGQVHCAFWDFENNNGLGGWNSSGCKVKETNVNYTICQ 2717
            M +  LA+P+ I   H     N   + C FWD       G W+S GC   E     T+C 
Sbjct: 189  MHVTKLAEPLEIVFSHQRPPPNM-TLTCVFWDVTKGT-TGDWSSEGCST-EVRPEGTVCC 245

Query: 2718 CDHLTHFGVLMDLSRSTVDSVNEQILALITYTGCGISSIFLGVAVVTY----IAFHKLRK 2773
            CDHLT F +L+   R T+D     IL  I+  GCG+S IFL   ++ Y    ++  + + 
Sbjct: 246  CDHLTFFALLL---RPTLDQSTVHILTRISQAGCGVSMIFLAFTIILYAFLRLSRERFKS 302

Query: 2774 DYPAKILINLCTALLMLNLVFLINSWLSSFQKVGVCITAAVALHYFLLVSFTWMGLEAVH 2833
            +   KI + L  +L +LNL FL+N    S      C       HYFLL +FTWMGLEA H
Sbjct: 303  EDAPKIHVALGGSLFLLNLAFLVNVGSGSKGSDAACWARGAVFHYFLLCAFTWMGLEAFH 362

Query: 2834 MYLALVKVFNIYIPNYILKFCLVGWGIPAIMVAITVSVKKDLYGTLS-------PTTPFC 2886
            +YL  V+VFN Y  +Y LK  LVGWG+PA+MV  T S     YG  +        +   C
Sbjct: 363  LYLLAVRVFNTYFGHYFLKLSLVGWGLPALMVIGTGSANS--YGLYTIRDRENRTSLELC 420

Query: 2887 WIKDDS---IFYISVVAYFCLIFLMNLSMFCTVLVQLNSVKSQIQKTRRKMILHDLKGTM 2943
            W ++ +     YI+V  YF + FL  + +   V+ ++ ++        R      +   +
Sbjct: 421  WFREGTTMYALYITVHGYFLITFLFGMVVLALVVWKIFTLSRATAVKERGKNRKKVLTLL 480

Query: 2944 SLTFLLGLTWGFAFFAWGPMRNFFLYLFAIFNTLQGFFIFVFHCVM 2989
             L+ L+G+TWG A F   P+    +Y+FA+FN+LQG FI  +  ++
Sbjct: 481  GLSSLVGVTWGLAIFT--PLGLSTVYIFALFNSLQGVFICCWFTIL 524


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.125    0.355 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 109,304,337
Number of Sequences: 37866
Number of extensions: 4910828
Number of successful extensions: 31890
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 113
Number of HSP's successfully gapped in prelim test: 408
Number of HSP's that attempted gapping in prelim test: 14418
Number of HSP's gapped (non-prelim): 3640
length of query: 3080
length of database: 18,247,518
effective HSP length: 121
effective length of query: 2959
effective length of database: 13,665,732
effective search space: 40436900988
effective search space used: 40436900988
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 71 (32.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.