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Search of human proteins with 58743319
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|58743319 arylsulfatase family, member H [Homo sapiens]
(562 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|58743319 arylsulfatase family, member H [Homo sapiens] 1194 0.0
gi|71852584 arylsulfatase D isoform a precursor [Homo sapiens] 781 0.0
gi|157266309 arylsulfatase E precursor [Homo sapiens] 711 0.0
gi|31742482 arylsulfatase F precursor [Homo sapiens] 707 0.0
gi|53831991 steryl-sulfatase precursor [Homo sapiens] 602 e-172
gi|71852586 arylsulfatase D isoform b precursor [Homo sapiens] 389 e-108
gi|4503899 galactosamine (N-acetyl)-6-sulfate sulfatase precurso... 156 5e-38
gi|146229331 arylsulfatase A isoform a precursor [Homo sapiens] 134 2e-31
gi|146229329 arylsulfatase A isoform a precursor [Homo sapiens] 134 2e-31
gi|146229324 arylsulfatase A isoform a precursor [Homo sapiens] 134 2e-31
gi|6005990 arylsulfatase A isoform a precursor [Homo sapiens] 134 2e-31
gi|45430057 Arylsulfatase G [Homo sapiens] 130 4e-30
gi|146229327 arylsulfatase A isoform b [Homo sapiens] 122 7e-28
gi|38569407 arylsulfatase B isoform 2 precursor [Homo sapiens] 87 3e-17
gi|38569405 arylsulfatase B isoform 1 precursor [Homo sapiens] 87 3e-17
gi|109389362 arylsulfatase J [Homo sapiens] 84 3e-16
gi|59797060 arylsulfatase family, member I [Homo sapiens] 82 1e-15
gi|5360208 iduronate-2-sulfatase isoform b precursor [Homo sapiens] 65 2e-10
gi|4557659 iduronate-2-sulfatase isoform a precursor [Homo sapiens] 65 2e-10
gi|4506919 N-sulfoglucosamine sulfohydrolase precursor [Homo sap... 64 3e-10
gi|39930577 arylsulfatase K [Homo sapiens] 48 2e-05
gi|240255483 sulfatase 2 isoform a precursor [Homo sapiens] 47 4e-05
gi|240255478 sulfatase 2 isoform b precursor [Homo sapiens] 47 4e-05
gi|29789100 sulfatase 2 isoform a precursor [Homo sapiens] 47 4e-05
gi|189571643 sulfatase 1 [Homo sapiens] 47 5e-05
gi|189571641 sulfatase 1 [Homo sapiens] 47 5e-05
gi|189571638 sulfatase 1 [Homo sapiens] 47 5e-05
gi|189571636 sulfatase 1 [Homo sapiens] 47 5e-05
gi|169217295 PREDICTED: similar to iduronate 2-sulfatase (Hunter... 46 1e-04
gi|4504061 glucosamine (N-acetyl)-6-sulfatase precursor [Homo sa... 39 0.013
>gi|58743319 arylsulfatase family, member H [Homo sapiens]
Length = 562
Score = 1194 bits (3088), Expect = 0.0
Identities = 562/562 (100%), Positives = 562/562 (100%)
Query: 1 MTRNARPNIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRA 60
MTRNARPNIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRA
Sbjct: 1 MTRNARPNIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRA 60
Query: 61 AFLTGRYPIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGKWHLGL 120
AFLTGRYPIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGKWHLGL
Sbjct: 61 AFLTGRYPIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGKWHLGL 120
Query: 121 SCASRNDHCYHPLNHGFHYFYGVPFGLLSDCQASKTPELHRWLRIKLWISTVALALVPFL 180
SCASRNDHCYHPLNHGFHYFYGVPFGLLSDCQASKTPELHRWLRIKLWISTVALALVPFL
Sbjct: 121 SCASRNDHCYHPLNHGFHYFYGVPFGLLSDCQASKTPELHRWLRIKLWISTVALALVPFL 180
Query: 181 LLIPKFARWFSVPWKVIFVFALLAFLFFTSWYSSYGFTRRWNCILMRNHEIIQQPMKEEK 240
LLIPKFARWFSVPWKVIFVFALLAFLFFTSWYSSYGFTRRWNCILMRNHEIIQQPMKEEK
Sbjct: 181 LLIPKFARWFSVPWKVIFVFALLAFLFFTSWYSSYGFTRRWNCILMRNHEIIQQPMKEEK 240
Query: 241 VASLMLKEALAFIERYKREPFLLFFSFLHVHTPLISKKKFVGRSKYGRYGDNVEEMDWMV 300
VASLMLKEALAFIERYKREPFLLFFSFLHVHTPLISKKKFVGRSKYGRYGDNVEEMDWMV
Sbjct: 241 VASLMLKEALAFIERYKREPFLLFFSFLHVHTPLISKKKFVGRSKYGRYGDNVEEMDWMV 300
Query: 301 GKILDALDQERLANHTLVYFTSDNGGHLEPLDGAVQLGGWNGIYKGGKGMGGWEGGIRVP 360
GKILDALDQERLANHTLVYFTSDNGGHLEPLDGAVQLGGWNGIYKGGKGMGGWEGGIRVP
Sbjct: 301 GKILDALDQERLANHTLVYFTSDNGGHLEPLDGAVQLGGWNGIYKGGKGMGGWEGGIRVP 360
Query: 361 GIFRWPSVLEAGRVINEPTSLMDIYPTLSYIGGGILSQDRVIDGQNLMPLLEGRASHSDH 420
GIFRWPSVLEAGRVINEPTSLMDIYPTLSYIGGGILSQDRVIDGQNLMPLLEGRASHSDH
Sbjct: 361 GIFRWPSVLEAGRVINEPTSLMDIYPTLSYIGGGILSQDRVIDGQNLMPLLEGRASHSDH 420
Query: 421 EFLFHYCGVYLHTVRWHQKDCATVWKAHYVTPKFYPEGTGACYGSGICSCSGDVTYHDPP 480
EFLFHYCGVYLHTVRWHQKDCATVWKAHYVTPKFYPEGTGACYGSGICSCSGDVTYHDPP
Sbjct: 421 EFLFHYCGVYLHTVRWHQKDCATVWKAHYVTPKFYPEGTGACYGSGICSCSGDVTYHDPP 480
Query: 481 LLFDISRDPSEALPLNPDNEPLFDSVIKKMEAAIREHRRTLTPVPQQFSVFNTIWKPWLQ 540
LLFDISRDPSEALPLNPDNEPLFDSVIKKMEAAIREHRRTLTPVPQQFSVFNTIWKPWLQ
Sbjct: 481 LLFDISRDPSEALPLNPDNEPLFDSVIKKMEAAIREHRRTLTPVPQQFSVFNTIWKPWLQ 540
Query: 541 PCCGTFPFCGCDKEDDILPMAP 562
PCCGTFPFCGCDKEDDILPMAP
Sbjct: 541 PCCGTFPFCGCDKEDDILPMAP 562
>gi|71852584 arylsulfatase D isoform a precursor [Homo sapiens]
Length = 593
Score = 781 bits (2018), Expect = 0.0
Identities = 363/560 (64%), Positives = 436/560 (77%), Gaps = 3/560 (0%)
Query: 2 TRNA-RPNIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRA 60
T NA +PNI+L+MADDLG GDL CYGNN++ TPNID+LA EGVRLTQHLAAA +CTPSRA
Sbjct: 35 TANAFKPNILLIMADDLGTGDLGCYGNNTLRTPNIDQLAEEGVRLTQHLAAAPLCTPSRA 94
Query: 61 AFLTGRYPIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGKWHLGL 120
AFLTGR+ RSGM A N RA W GSGGLP NETTFA++LQ GY TGLIGKWH G+
Sbjct: 95 AFLTGRHSFRSGM-DASNGYRALQWNAGSGGLPENETTFARILQQHGYATGLIGKWHQGV 153
Query: 121 SCASRNDHCYHPLNHGFHYFYGVPFGLLSDCQASKTPELHRWLRIKLWISTVALALVPFL 180
+CASR DHC+HPLNHGF YFYG+PF L +DC + PE+ LR +LW T LAL
Sbjct: 154 NCASRGDHCHHPLNHGFDYFYGMPFTLTNDCDPGRPPEVDAALRAQLWGYTQFLALGILT 213
Query: 181 LLIPKFARWFSVPWKVIFVFALLAFLFFTSWYSSYGFTRRWNCILMRNHEIIQQPMKEEK 240
L + +FSV + + A + LFF SWYSS+GF RRWNCILMRNH++ +QPM EK
Sbjct: 214 LAAGQTCGFFSVSARAVTGMAGVGCLFFISWYSSFGFVRRWNCILMRNHDVTEQPMVLEK 273
Query: 241 VASLMLKEALAFIERYKREPFLLFFSFLHVHTPLISKKKFVGRSKYGRYGDNVEEMDWMV 300
ASLMLKEA+++IER+K PFLLF S LHVH PL++ F+G+S++G YGDNVEEMDW++
Sbjct: 274 TASLMLKEAVSYIERHKHGPFLLFLSLLHVHIPLVTTSAFLGKSQHGLYGDNVEEMDWLI 333
Query: 301 GKILDALDQERLANHTLVYFTSDNGGHLEPLDGAVQLGGWNGIYKGGKGMGGWEGGIRVP 360
GK+L+A++ L N T YFTSD+GGHLE DG QLGGWNGIYKGGKGMGGWEGGIRVP
Sbjct: 334 GKVLNAIEDNGLKNSTFTYFTSDHGGHLEARDGHSQLGGWNGIYKGGKGMGGWEGGIRVP 393
Query: 361 GIFRWPSVLEAGRVINEPTSLMDIYPTLSYIGGGILSQDRVIDGQNLMPLLEGRASHSDH 420
GIF WP VL AGRVI EPTSLMD++PT+ + GG + QDRVIDG +L+PLL+G + S H
Sbjct: 394 GIFHWPGVLPAGRVIGEPTSLMDVFPTVVQLVGGEVPQDRVIDGHSLVPLLQGAEARSAH 453
Query: 421 EFLFHYCGVYLHTVRWHQKDCATVWKAHYVTPKFYPEGTGACYGSGICSCSGD-VTYHDP 479
EFLFHYCG +LH RWHQKD +VWK HY TP+F+PEG GACYG G+C CSG+ VT+H P
Sbjct: 454 EFLFHYCGQHLHAARWHQKDSGSVWKVHYTTPQFHPEGAGACYGRGVCPCSGEGVTHHRP 513
Query: 480 PLLFDISRDPSEALPLNPDNEPLFDSVIKKMEAAIREHRRTLTPVPQQFSVFNTIWKPWL 539
PLLFD+SRDPSEA PL PD+EPL+ +VI ++ AA+ EHR+TL+PVPQQFS+ N +WKPWL
Sbjct: 514 PLLFDLSRDPSEARPLTPDSEPLYHAVIARVGAAVSEHRQTLSPVPQQFSMSNILWKPWL 573
Query: 540 QPCCGTFPFCGCDKEDDILP 559
QPCCG FPFC C ++ D P
Sbjct: 574 QPCCGHFPFCSCHEDGDGTP 593
>gi|157266309 arylsulfatase E precursor [Homo sapiens]
Length = 589
Score = 711 bits (1836), Expect = 0.0
Identities = 336/553 (60%), Positives = 407/553 (73%), Gaps = 2/553 (0%)
Query: 5 ARPNIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRAAFLT 64
+RPNI+LLMADDLG+GD+ CYGNN++ TPNIDRLA +GV+LTQH++AAS+CTPSRAAFLT
Sbjct: 36 SRPNILLLMADDLGIGDIGCYGNNTMRTPNIDRLAEDGVKLTQHISAASLCTPSRAAFLT 95
Query: 65 GRYPIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGKWHLGLSCAS 124
GRYP+RSGMVS+ R W G SGGLPTNETTFAK+L+ +GY TGLIGKWHLGL+C S
Sbjct: 96 GRYPVRSGMVSSIGY-RVLQWTGASGGLPTNETTFAKILKEKGYATGLIGKWHLGLNCES 154
Query: 125 RNDHCYHPLNHGFHYFYGVPFGLLSDCQASKTPELHRWLRIKLWISTVALALVPFLLLIP 184
+DHC+HPL+HGF +FYG+PF L+ DC + E L KL LALV L+
Sbjct: 155 ASDHCHHPLHHGFDHFYGMPFSLMGDCARWELSEKRVNLEQKLNFLFQVLALVALTLVAG 214
Query: 185 KFARWFSVPWKVIFVFALLAFLFFTSWYSSYGFTRRWNCILMRNHEIIQQPMKEEKVASL 244
K V W + AL A L S Y +C LMRNH I +QPM ++ L
Sbjct: 215 KLTHLIPVSWMPVIWSALSAVLLLASSYFVGALIVHADCFLMRNHTITEQPMCFQRTTPL 274
Query: 245 MLKEALAFIERYKREPFLLFFSFLHVHTPLISKKKFVGRSKYGRYGDNVEEMDWMVGKIL 304
+L+E +F++R K PFLLF SFLHVH PLI+ + F+G+S +G YGDNVEEMDWMVG+IL
Sbjct: 275 ILQEVASFLKRNKHGPFLLFVSFLHVHIPLITMENFLGKSLHGLYGDNVEEMDWMVGRIL 334
Query: 305 DALDQERLANHTLVYFTSDNGGHLEPLDGAVQLGGWNGIYKGGKGMGGWEGGIRVPGIFR 364
D LD E L+N TL+YFTSD+GG LE G Q GGWNGIYKGGKGMGGWEGGIRVPGIFR
Sbjct: 335 DTLDVEGLSNSTLIYFTSDHGGSLENQLGNTQYGGWNGIYKGGKGMGGWEGGIRVPGIFR 394
Query: 365 WPSVLEAGRVINEPTSLMDIYPTLSYIGGGILSQDRVIDGQNLMPLLEGRASHSDHEFLF 424
WP VL AGRVI EPTSLMD++PT+ + GG + QDRVIDGQ+L+PLL G A HSDHEFL
Sbjct: 395 WPGVLPAGRVIGEPTSLMDVFPTVVRLAGGEVPQDRVIDGQDLLPLLLGTAQHSDHEFLM 454
Query: 425 HYCGVYLHTVRWHQKDCATVWKAHYVTPKFYPEGTGACYGSGICSCSGD-VTYHDPPLLF 483
HYC +LH RWHQ+D T+WK H+VTP F PEG GACYG +C C G+ V +HDPPLLF
Sbjct: 455 HYCERFLHAARWHQRDRGTMWKVHFVTPVFQPEGAGACYGRKVCPCFGEKVVHHDPPLLF 514
Query: 484 DISRDPSEALPLNPDNEPLFDSVIKKMEAAIREHRRTLTPVPQQFSVFNTIWKPWLQPCC 543
D+SRDPSE L P +EP+F V+++++ A+ EH+RTL+PVP Q IW+PWLQPCC
Sbjct: 515 DLSRDPSETHILTPASEPVFYQVMERVQQAVWEHQRTLSPVPLQLDRLGNIWRPWLQPCC 574
Query: 544 GTFPFCGCDKEDD 556
G FP C C +EDD
Sbjct: 575 GPFPLCWCLREDD 587
>gi|31742482 arylsulfatase F precursor [Homo sapiens]
Length = 590
Score = 707 bits (1824), Expect = 0.0
Identities = 335/554 (60%), Positives = 410/554 (74%), Gaps = 4/554 (0%)
Query: 6 RPNIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRAAFLTG 65
+PNIVL+M DDLG+GDL CYGN+++ TP+IDRLA EGVRLTQH++AAS+C+PSR+AFLTG
Sbjct: 29 KPNIVLIMVDDLGIGDLGCYGNDTMRTPHIDRLAREGVRLTQHISAASLCSPSRSAFLTG 88
Query: 66 RYPIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGKWHLGLSCASR 125
RYPIRSGMVS+ N R L GLP NETT A LL+ +GY TGLIGKWH GL+C SR
Sbjct: 89 RYPIRSGMVSSGN-RRVIQNLAVPAGLPLNETTLAALLKKQGYSTGLIGKWHQGLNCDSR 147
Query: 126 NDHCYHPLNHGFHYFYGVPFGLLSDCQASKTPELHRWLRIKLWISTVALALVPFLLLIPK 185
+D C+HP N+GF Y+YG+PF L+ C + +LW+ +A+ L K
Sbjct: 148 SDQCHHPYNYGFDYYYGMPFTLVDSCWPDPSRNTELAFESQLWLCVQLVAIAILTLTFGK 207
Query: 186 FARWFSVPWKVIFVFALLAFLFFTSWYSSYGFTRRWNCILMRNHEIIQQPMKEEKVASLM 245
+ W SVPW +IF L FL +W+SS+ W+C+LMR HEI +QPMK E+ S+M
Sbjct: 208 LSGWVSVPWLLIFSMILFIFLLGYAWFSSHTSPLYWDCLLMRGHEITEQPMKAERAGSIM 267
Query: 246 LKEALAFIERYKREPFLLFFSFLHVHTPLISKKKFVGRSKYGRYGDNVEEMDWMVGKILD 305
+KEA++F+ER+ +E FLLFFSFLHVHTPL + F G SK+G YGDNVEEMD MVGKILD
Sbjct: 268 VKEAISFLERHSKETFLLFFSFLHVHTPLPTTDDFTGTSKHGLYGDNVEEMDSMVGKILD 327
Query: 306 ALDQERLANHTLVYFTSDNGGHLEPLDGAVQLGGWNGIYKGGKGMGGWEGGIRVPGIFRW 365
A+D L N+TLVYFTSD+GGHLE G QLGGWNGIYKGGKGMGGWEGGIRVPGI RW
Sbjct: 328 AIDDFGLRNNTLVYFTSDHGGHLEARRGHAQLGGWNGIYKGGKGMGGWEGGIRVPGIVRW 387
Query: 366 PSVLEAGRVINEPTSLMDIYPTLSYIGGGILSQDRVIDGQNLMPLLEGRASHSDHEFLFH 425
P + AGR+I EPTSLMDI PT++ + GG L QDRVIDG++LMPLL+G HS+HEFLFH
Sbjct: 388 PGKVPAGRLIKEPTSLMDILPTVASVSGGSLPQDRVIDGRDLMPLLQGNVRHSEHEFLFH 447
Query: 426 YCGVYLHTVRWHQK-DCATVWKAHYVTPKFYPEGTGACYGSGICSCSGD-VTYHDPPLLF 483
YCG YLH VRW K D +VWKAHYVTP F P +G CY + +C C G+ VTYH+PPLLF
Sbjct: 448 YCGSYLHAVRWIPKDDSGSVWKAHYVTPVFQPPASGGCYVTSLCRCFGEQVTYHNPPLLF 507
Query: 484 DISRDPSEALPLNPDNEPLFDSVIKKMEAAIREHRRTLTPVPQQFSVFNTIWKPWLQPCC 543
D+SRDPSE+ PL P EPL D VIKK+ A++EH+ T+ PV Q S N + WL+PCC
Sbjct: 508 DLSRDPSESTPLTPATEPLHDFVIKKVANALKEHQETIVPVTYQLSELNQ-GRTWLKPCC 566
Query: 544 GTFPFCGCDKEDDI 557
G FPFC CDKE+++
Sbjct: 567 GVFPFCLCDKEEEV 580
>gi|53831991 steryl-sulfatase precursor [Homo sapiens]
Length = 583
Score = 602 bits (1552), Expect = e-172
Identities = 299/557 (53%), Positives = 381/557 (68%), Gaps = 13/557 (2%)
Query: 5 ARPNIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRAAFLT 64
+RPNI+L+MADDLG+GD CYGN ++ TPNIDRLAS GV+LTQHLAA+ +CTPSRAAF+T
Sbjct: 25 SRPNIILVMADDLGIGDPGCYGNKTIRTPNIDRLASGGVKLTQHLAASPLCTPSRAAFMT 84
Query: 65 GRYPIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGKWHLGLSCAS 124
GRYP+RSGM S ++ F + SGGLPT+E TFAKLL+ +GY T LIGKWHLG+SC S
Sbjct: 85 GRYPVRSGMAS-WSRTGVFLFTASSGGLPTDEITFAKLLKDQGYSTALIGKWHLGMSCHS 143
Query: 125 RNDHCYHPLNHGFHYFYGVPFGLLSDCQASK----TPELHRWLRIKLWISTVALALVPFL 180
+ D C+HPL+HGF+YFYG+ L DC+ + T R + + L I V L + L
Sbjct: 144 KTDFCHHPLHHGFNYFYGISLTNLRDCKPGEGSVFTTGFKRLVFLPLQIVGVTLLTLAAL 203
Query: 181 LLIPKFARWFSVPWKVIFVFALLAFLFFTSWYSSYGFTRRWNCILMRNHEIIQQPMKEEK 240
+ VP V F LA L T + + R NC +MRN+EIIQQPM +
Sbjct: 204 NCLGLL----HVPLGVFFSLLFLAALILTLFLGFLHYFRPLNCFMMRNYEIIQQPMSYDN 259
Query: 241 VASLMLKEALAFIERYKREPFLLFFSFLHVHTPLISKKKFVGRSKYGRYGDNVEEMDWMV 300
+ + EA FI+R PFLL S+LHVHT L S K F G+S++G YGD VEEMDW V
Sbjct: 260 LTQRLTVEAAQFIQRNTETPFLLVLSYLHVHTALFSSKDFAGKSQHGVYGDAVEEMDWSV 319
Query: 301 GKILDALDQERLANHTLVYFTSDNGGHLEPLDGAVQL-GGWNGIYKGGKGMGGWEGGIRV 359
G+IL+ LD+ RLAN TL+YFTSD G H+E + ++ GG NGIYKGGK WEGGIRV
Sbjct: 320 GQILNLLDELRLANDTLIYFTSDQGAHVEEVSSKGEIHGGSNGIYKGGKA-NNWEGGIRV 378
Query: 360 PGIFRWPSVLEAGRVINEPTSLMDIYPTLSYIGGGILSQDRVIDGQNLMPLLEGRASHSD 419
PGI RWP V++AG+ I+EPTS MDI+PT++ + G L +DR+IDG++LMPLLEG++ SD
Sbjct: 379 PGILRWPRVIQAGQKIDEPTSNMDIFPTVAKLAGAPLPEDRIIDGRDLMPLLEGKSQRSD 438
Query: 420 HEFLFHYCGVYLHTVRWHQKDCATVWKAHYVTPKFYPEGTGACYGSGICSCSGD-VTYHD 478
HEFLFHYC YL+ VRWH ++ ++WKA + TP F P G+ C+ + +C C G VT+HD
Sbjct: 439 HEFLFHYCNAYLNAVRWHPQNSTSIWKAFFFTPNFNPVGSNGCFATHVCFCFGSYVTHHD 498
Query: 479 PPLLFDISRDPSEALPLNPDNEPLFDSVIKKMEAAIREHRRTLTPVPQQFSVFNTIWKPW 538
PPLLFDIS+DP E PL P +EP F ++K M+ A H +TL VP QFS N +WKPW
Sbjct: 499 PPLLFDISKDPRERNPLTPASEPRFYEILKVMQEAADRHTQTLPEVPDQFSWNNFLWKPW 558
Query: 539 LQPCC-GTFPFCGCDKE 554
LQ CC T C CD+E
Sbjct: 559 LQLCCPSTGLSCQCDRE 575
>gi|71852586 arylsulfatase D isoform b precursor [Homo sapiens]
Length = 382
Score = 389 bits (998), Expect = e-108
Identities = 188/300 (62%), Positives = 227/300 (75%), Gaps = 2/300 (0%)
Query: 2 TRNA-RPNIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRA 60
T NA +PNI+L+MADDLG GDL CYGNN++ TPNID+LA EGVRLTQHLAAA +CTPSRA
Sbjct: 35 TANAFKPNILLIMADDLGTGDLGCYGNNTLRTPNIDQLAEEGVRLTQHLAAAPLCTPSRA 94
Query: 61 AFLTGRYPIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGKWHLGL 120
AFLTGR+ RSGM A N RA W GSGGLP NETTFA++LQ GY TGLIGKWH G+
Sbjct: 95 AFLTGRHSFRSGM-DASNGYRALQWNAGSGGLPENETTFARILQQHGYATGLIGKWHQGV 153
Query: 121 SCASRNDHCYHPLNHGFHYFYGVPFGLLSDCQASKTPELHRWLRIKLWISTVALALVPFL 180
+CASR DHC+HPLNHGF YFYG+PF L +DC + PE+ LR +LW T LAL
Sbjct: 154 NCASRGDHCHHPLNHGFDYFYGMPFTLTNDCDPGRPPEVDAALRAQLWGYTQFLALGILT 213
Query: 181 LLIPKFARWFSVPWKVIFVFALLAFLFFTSWYSSYGFTRRWNCILMRNHEIIQQPMKEEK 240
L + +FSV + + A + LFF SWYSS+GF RRWNCILMRNH++ +QPM EK
Sbjct: 214 LAAGQTCGFFSVSARAVTGMAGVGCLFFISWYSSFGFVRRWNCILMRNHDVTEQPMVLEK 273
Query: 241 VASLMLKEALAFIERYKREPFLLFFSFLHVHTPLISKKKFVGRSKYGRYGDNVEEMDWMV 300
ASLMLKEA+++IER+K PFLLF S LHVH PL++ F+G+S++G YGDNVEEMDW++
Sbjct: 274 TASLMLKEAVSYIERHKHGPFLLFLSLLHVHIPLVTTSAFLGKSQHGLYGDNVEEMDWLI 333
>gi|4503899 galactosamine (N-acetyl)-6-sulfate sulfatase precursor
[Homo sapiens]
Length = 522
Score = 156 bits (394), Expect = 5e-38
Identities = 109/323 (33%), Positives = 165/323 (51%), Gaps = 28/323 (8%)
Query: 238 EEKVASLMLKEALAFIERYKRE-PFLLFFSFLHVHTPLISKKKFVGRSKYGRYGDNVEEM 296
E + + L+EAL FI+R R PF L+++ H P+ + K F+G S+ GRYGD V E+
Sbjct: 202 EANLTQIYLQEALDFIKRQARHHPFFLYWAVDATHAPVYASKPFLGTSQRGRYGDAVREI 261
Query: 297 DWMVGKILDALDQERLANHTLVYFTSDNGGHLEPLDGAVQLGGWNGIYKGGKGMGGWEGG 356
D +GKIL+ L +A++T V+FTSDNG L A + GG NG + GK +EGG
Sbjct: 262 DDSIGKILELLQDLHVADNTFVFFTSDNGA---ALISAPEQGGSNGPFLCGK-QTTFEGG 317
Query: 357 IRVPGIFRWPSVLEAGRVINEPTSLMDIYPTLSYIGGGILSQDRVIDGQNLMP-LLEGRA 415
+R P + WP + AG+V ++ S+MD++ T + G DR IDG NL+P LL+GR
Sbjct: 318 MREPALAWWPGHVTAGQVSHQLGSIMDLFTTSLALAGLTPPSDRAIDGLNLLPTLLQGRL 377
Query: 416 SHSDHEFLFHYCGVYLHTVRWHQKDCATVWKAHYVT----PKFYPEGTGACYGSGICSCS 471
+F+Y G L Q KAH+ T + + +G C G + S
Sbjct: 378 MDRP---IFYYRGDTLMAATLGQH------KAHFWTWTNSWENFRQGIDFCPGQNV---S 425
Query: 472 GDVTYH-----DPPLLFDISRDPSEALPLNPDNEPLFDSVIKKMEAAIREHRRTLTPVPQ 526
G T++ PL+F + RDP E PL+ + + + ++ + +++H+ L P
Sbjct: 426 GVTTHNLEDHTKLPLIFHLGRDPGERFPLSFASAE-YQEALSRITSVVQQHQEALVPAQP 484
Query: 527 QFSVFNTIWKPWLQPCCGTFPFC 549
Q +V N W P C C
Sbjct: 485 QLNVCNWAVMNWAPPGCEKLGKC 507
Score = 117 bits (294), Expect = 2e-26
Identities = 65/160 (40%), Positives = 91/160 (56%), Gaps = 10/160 (6%)
Query: 7 PNIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRAAFLTGR 66
PNI+LL+ DD+G GDL YG S TPN+DR+A+EG+ +A +C+PSRAA LTGR
Sbjct: 31 PNILLLLMDDMGWGDLGVYGEPSRETPNLDRMAAEGLLFPNFYSANPLCSPSRAALLTGR 90
Query: 67 YPIRSGMVSA-YNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGKWHLGLSCASR 125
PIR+G + + A+T GG+P +E +LL+ GY + ++GKWHLG
Sbjct: 91 LPIRNGFYTTNAHARNAYTPQEIVGGIPDSEQLLPELLKKAGYVSKIVGKWHLG------ 144
Query: 126 NDHCYHPLNHGFHYFYGVP---FGLLSDCQASKTPELHRW 162
+ +HPL HGF ++G P FG + P W
Sbjct: 145 HRPQFHPLKHGFDEWFGSPNCHFGPYDNKARPNIPVYRDW 184
>gi|146229331 arylsulfatase A isoform a precursor [Homo sapiens]
Length = 507
Score = 134 bits (337), Expect = 2e-31
Identities = 68/139 (48%), Positives = 87/139 (62%), Gaps = 10/139 (7%)
Query: 7 PNIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRAAFLTGR 66
PNIVL+ ADDLG GDL CYG+ S +TPN+D+LA+ G+R T S+CTPSRAA LTGR
Sbjct: 21 PNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPSRAALLTGR 80
Query: 67 YPIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGKWHLGLSCASRN 126
P+R GM + GGLP E T A++L RGY TG+ GKWHLG+
Sbjct: 81 LPVRMGMYPGVLVP------SSRGGLPLEEVTVAEVLAARGYLTGMAGKWHLGVG----P 130
Query: 127 DHCYHPLNHGFHYFYGVPF 145
+ + P + GFH F G+P+
Sbjct: 131 EGAFLPPHQGFHRFLGIPY 149
Score = 122 bits (307), Expect = 7e-28
Identities = 87/244 (35%), Positives = 126/244 (51%), Gaps = 13/244 (5%)
Query: 248 EALAFIERYKREPFLLFFSFLHVHTPLISKKKFVGRSKYGRYGDNVEEMDWMVGKILDAL 307
+ +A +R R PF L+++ H H P S + F RS G +GD++ E+D VG ++ A+
Sbjct: 207 DLMADAQRQDR-PFFLYYASHHTHYPQFSGQSFAERSGRGPFGDSLMELDAAVGTLMTAI 265
Query: 308 DQERLANHTLVYFTSDNGGHLEPLDGAVQLGGWNGIYKGGKGMGGWEGGIRVPGIFRWPS 367
L TLV FT+DNG P + GG +G+ + GKG +EGG+R P + WP
Sbjct: 266 GDLGLLEETLVIFTADNG----PETMRMSRGGCSGLLRCGKGT-TYEGGVREPALAFWPG 320
Query: 368 VLEAGRVINEPTSLMDIYPTLSYIGGGILSQDRVIDGQNLMPLLEGRASHSDHEFLFHYC 427
+ G V +E S +D+ PTL+ + G L + +DG +L PLL G S + LF Y
Sbjct: 321 HIAPG-VTHELASSLDLLPTLAALAGAPL-PNVTLDGFDLSPLLLG-TGKSPRQSLFFYP 377
Query: 428 GVYLHTVRWHQKDCATVWKAHYVTPKFYPEGTGACYGSGICSCSGDVTYHDPPLLFDISR 487
Y VR +KAH+ T T A C S +T H+PPLL+D+S+
Sbjct: 378 S-YPDEVRGVFAVRTGKYKAHFFTQGSAHSDTTA---DPACHASSSLTAHEPPLLYDLSK 433
Query: 488 DPSE 491
DP E
Sbjct: 434 DPGE 437
>gi|146229329 arylsulfatase A isoform a precursor [Homo sapiens]
Length = 507
Score = 134 bits (337), Expect = 2e-31
Identities = 68/139 (48%), Positives = 87/139 (62%), Gaps = 10/139 (7%)
Query: 7 PNIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRAAFLTGR 66
PNIVL+ ADDLG GDL CYG+ S +TPN+D+LA+ G+R T S+CTPSRAA LTGR
Sbjct: 21 PNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPSRAALLTGR 80
Query: 67 YPIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGKWHLGLSCASRN 126
P+R GM + GGLP E T A++L RGY TG+ GKWHLG+
Sbjct: 81 LPVRMGMYPGVLVP------SSRGGLPLEEVTVAEVLAARGYLTGMAGKWHLGVG----P 130
Query: 127 DHCYHPLNHGFHYFYGVPF 145
+ + P + GFH F G+P+
Sbjct: 131 EGAFLPPHQGFHRFLGIPY 149
Score = 122 bits (307), Expect = 7e-28
Identities = 87/244 (35%), Positives = 126/244 (51%), Gaps = 13/244 (5%)
Query: 248 EALAFIERYKREPFLLFFSFLHVHTPLISKKKFVGRSKYGRYGDNVEEMDWMVGKILDAL 307
+ +A +R R PF L+++ H H P S + F RS G +GD++ E+D VG ++ A+
Sbjct: 207 DLMADAQRQDR-PFFLYYASHHTHYPQFSGQSFAERSGRGPFGDSLMELDAAVGTLMTAI 265
Query: 308 DQERLANHTLVYFTSDNGGHLEPLDGAVQLGGWNGIYKGGKGMGGWEGGIRVPGIFRWPS 367
L TLV FT+DNG P + GG +G+ + GKG +EGG+R P + WP
Sbjct: 266 GDLGLLEETLVIFTADNG----PETMRMSRGGCSGLLRCGKGT-TYEGGVREPALAFWPG 320
Query: 368 VLEAGRVINEPTSLMDIYPTLSYIGGGILSQDRVIDGQNLMPLLEGRASHSDHEFLFHYC 427
+ G V +E S +D+ PTL+ + G L + +DG +L PLL G S + LF Y
Sbjct: 321 HIAPG-VTHELASSLDLLPTLAALAGAPL-PNVTLDGFDLSPLLLG-TGKSPRQSLFFYP 377
Query: 428 GVYLHTVRWHQKDCATVWKAHYVTPKFYPEGTGACYGSGICSCSGDVTYHDPPLLFDISR 487
Y VR +KAH+ T T A C S +T H+PPLL+D+S+
Sbjct: 378 S-YPDEVRGVFAVRTGKYKAHFFTQGSAHSDTTA---DPACHASSSLTAHEPPLLYDLSK 433
Query: 488 DPSE 491
DP E
Sbjct: 434 DPGE 437
>gi|146229324 arylsulfatase A isoform a precursor [Homo sapiens]
Length = 507
Score = 134 bits (337), Expect = 2e-31
Identities = 68/139 (48%), Positives = 87/139 (62%), Gaps = 10/139 (7%)
Query: 7 PNIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRAAFLTGR 66
PNIVL+ ADDLG GDL CYG+ S +TPN+D+LA+ G+R T S+CTPSRAA LTGR
Sbjct: 21 PNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPSRAALLTGR 80
Query: 67 YPIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGKWHLGLSCASRN 126
P+R GM + GGLP E T A++L RGY TG+ GKWHLG+
Sbjct: 81 LPVRMGMYPGVLVP------SSRGGLPLEEVTVAEVLAARGYLTGMAGKWHLGVG----P 130
Query: 127 DHCYHPLNHGFHYFYGVPF 145
+ + P + GFH F G+P+
Sbjct: 131 EGAFLPPHQGFHRFLGIPY 149
Score = 122 bits (307), Expect = 7e-28
Identities = 87/244 (35%), Positives = 126/244 (51%), Gaps = 13/244 (5%)
Query: 248 EALAFIERYKREPFLLFFSFLHVHTPLISKKKFVGRSKYGRYGDNVEEMDWMVGKILDAL 307
+ +A +R R PF L+++ H H P S + F RS G +GD++ E+D VG ++ A+
Sbjct: 207 DLMADAQRQDR-PFFLYYASHHTHYPQFSGQSFAERSGRGPFGDSLMELDAAVGTLMTAI 265
Query: 308 DQERLANHTLVYFTSDNGGHLEPLDGAVQLGGWNGIYKGGKGMGGWEGGIRVPGIFRWPS 367
L TLV FT+DNG P + GG +G+ + GKG +EGG+R P + WP
Sbjct: 266 GDLGLLEETLVIFTADNG----PETMRMSRGGCSGLLRCGKGT-TYEGGVREPALAFWPG 320
Query: 368 VLEAGRVINEPTSLMDIYPTLSYIGGGILSQDRVIDGQNLMPLLEGRASHSDHEFLFHYC 427
+ G V +E S +D+ PTL+ + G L + +DG +L PLL G S + LF Y
Sbjct: 321 HIAPG-VTHELASSLDLLPTLAALAGAPL-PNVTLDGFDLSPLLLG-TGKSPRQSLFFYP 377
Query: 428 GVYLHTVRWHQKDCATVWKAHYVTPKFYPEGTGACYGSGICSCSGDVTYHDPPLLFDISR 487
Y VR +KAH+ T T A C S +T H+PPLL+D+S+
Sbjct: 378 S-YPDEVRGVFAVRTGKYKAHFFTQGSAHSDTTA---DPACHASSSLTAHEPPLLYDLSK 433
Query: 488 DPSE 491
DP E
Sbjct: 434 DPGE 437
>gi|6005990 arylsulfatase A isoform a precursor [Homo sapiens]
Length = 507
Score = 134 bits (337), Expect = 2e-31
Identities = 68/139 (48%), Positives = 87/139 (62%), Gaps = 10/139 (7%)
Query: 7 PNIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRAAFLTGR 66
PNIVL+ ADDLG GDL CYG+ S +TPN+D+LA+ G+R T S+CTPSRAA LTGR
Sbjct: 21 PNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPSRAALLTGR 80
Query: 67 YPIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGKWHLGLSCASRN 126
P+R GM + GGLP E T A++L RGY TG+ GKWHLG+
Sbjct: 81 LPVRMGMYPGVLVP------SSRGGLPLEEVTVAEVLAARGYLTGMAGKWHLGVG----P 130
Query: 127 DHCYHPLNHGFHYFYGVPF 145
+ + P + GFH F G+P+
Sbjct: 131 EGAFLPPHQGFHRFLGIPY 149
Score = 122 bits (307), Expect = 7e-28
Identities = 87/244 (35%), Positives = 126/244 (51%), Gaps = 13/244 (5%)
Query: 248 EALAFIERYKREPFLLFFSFLHVHTPLISKKKFVGRSKYGRYGDNVEEMDWMVGKILDAL 307
+ +A +R R PF L+++ H H P S + F RS G +GD++ E+D VG ++ A+
Sbjct: 207 DLMADAQRQDR-PFFLYYASHHTHYPQFSGQSFAERSGRGPFGDSLMELDAAVGTLMTAI 265
Query: 308 DQERLANHTLVYFTSDNGGHLEPLDGAVQLGGWNGIYKGGKGMGGWEGGIRVPGIFRWPS 367
L TLV FT+DNG P + GG +G+ + GKG +EGG+R P + WP
Sbjct: 266 GDLGLLEETLVIFTADNG----PETMRMSRGGCSGLLRCGKGT-TYEGGVREPALAFWPG 320
Query: 368 VLEAGRVINEPTSLMDIYPTLSYIGGGILSQDRVIDGQNLMPLLEGRASHSDHEFLFHYC 427
+ G V +E S +D+ PTL+ + G L + +DG +L PLL G S + LF Y
Sbjct: 321 HIAPG-VTHELASSLDLLPTLAALAGAPL-PNVTLDGFDLSPLLLG-TGKSPRQSLFFYP 377
Query: 428 GVYLHTVRWHQKDCATVWKAHYVTPKFYPEGTGACYGSGICSCSGDVTYHDPPLLFDISR 487
Y VR +KAH+ T T A C S +T H+PPLL+D+S+
Sbjct: 378 S-YPDEVRGVFAVRTGKYKAHFFTQGSAHSDTTA---DPACHASSSLTAHEPPLLYDLSK 433
Query: 488 DPSE 491
DP E
Sbjct: 434 DPGE 437
>gi|45430057 Arylsulfatase G [Homo sapiens]
Length = 525
Score = 130 bits (326), Expect = 4e-30
Identities = 68/156 (43%), Positives = 94/156 (60%), Gaps = 15/156 (9%)
Query: 2 TRNARPNIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRAA 61
TR +PN V+++ADD+G GDL + T N+D++ASEG+R AAAS C+PSRA+
Sbjct: 31 TRGQKPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTCSPSRAS 90
Query: 62 FLTGRYPIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGKWHLGLS 121
LTGR +R+G+ + + GGLP NETT A++LQ GY TG+IGKWHLG
Sbjct: 91 LLTGRLGLRNGVTRNFAVTSV-------GGLPLNETTLAEVLQQAGYVTGIIGKWHLG-- 141
Query: 122 CASRNDHCYHPLNHGFHYFYGVPFGLLSDCQASKTP 157
+ YHP GF Y++G+P+ D + TP
Sbjct: 142 ----HHGSYHPNFRGFDYYFGIPYS--HDMGCTDTP 171
Score = 122 bits (305), Expect = 1e-27
Identities = 102/346 (29%), Positives = 155/346 (44%), Gaps = 45/346 (13%)
Query: 225 LMRNHEIIQQPMKEEKVASLMLKEALAFIERYKRE--PFLLFFSFLHVHTPLISKKKFVG 282
L N I++QP+ +A ++A FI+R PFLL+ + H+H PL +
Sbjct: 203 LYENLNIVEQPVNLSSLAQKYAEKATQFIQRASTSGRPFLLYVALAHMHVPLPVTQLPAA 262
Query: 283 RSKYGRYGDNVEEMDWMVGKILDALDQERLANHTLVYFTSDNGGHLEPLDGAVQLGGWNG 342
YG + EMD +VG+I D +D + +T ++FT DNG + + A +G + G
Sbjct: 263 PRGRSLYGAGLWEMDSLVGQIKDKVDHT-VKENTFLWFTGDNGPWAQKCELAGSVGPFTG 321
Query: 343 IYKGGKG-----MGGWEGGIRVPGIFRWPSVLEAGRVINEPTSLMDIYPTLSYIGGGILS 397
++ +G WEGG RVP + WP + S++DI+PT+ + L
Sbjct: 322 FWQTRQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSTALLSVLDIFPTVVALAQASLP 381
Query: 398 QDRVIDGQNLMPLLEGRASHSDHEFLFH----YCGVY--LHTVRWHQKDCATVWKAHYVT 451
Q R DG ++ +L GR S H LFH G + L TVR + +KA Y+T
Sbjct: 382 QGRRFDGVDVSEVLFGR-SQPGHRVLFHPNSGAAGEFGALQTVRLER------YKAFYIT 434
Query: 452 PKFYPEGTGACYGSGICSCSGDVTYHDPPLLFDISRDPSEALPLNPDNEPLFDSVIKKME 511
G AC GS +G H PL+F++ D +EA+PL + +
Sbjct: 435 -----GGARACDGS-----TGPELQHKFPLIFNLEDDTAEAVPLERGG--------AEYQ 476
Query: 512 AAIREHRRTLTPVPQQFSVFNT-----IWKPWLQPCCGTFPF-CGC 551
A + E R+ L V Q + N P + PCC + C C
Sbjct: 477 AVLPEVRKVLADVLQDIANDNISSADYTQDPSVTPCCNPYQIACRC 522
>gi|146229327 arylsulfatase A isoform b [Homo sapiens]
Length = 423
Score = 122 bits (307), Expect = 7e-28
Identities = 87/244 (35%), Positives = 126/244 (51%), Gaps = 13/244 (5%)
Query: 248 EALAFIERYKREPFLLFFSFLHVHTPLISKKKFVGRSKYGRYGDNVEEMDWMVGKILDAL 307
+ +A +R R PF L+++ H H P S + F RS G +GD++ E+D VG ++ A+
Sbjct: 123 DLMADAQRQDR-PFFLYYASHHTHYPQFSGQSFAERSGRGPFGDSLMELDAAVGTLMTAI 181
Query: 308 DQERLANHTLVYFTSDNGGHLEPLDGAVQLGGWNGIYKGGKGMGGWEGGIRVPGIFRWPS 367
L TLV FT+DNG P + GG +G+ + GKG +EGG+R P + WP
Sbjct: 182 GDLGLLEETLVIFTADNG----PETMRMSRGGCSGLLRCGKGT-TYEGGVREPALAFWPG 236
Query: 368 VLEAGRVINEPTSLMDIYPTLSYIGGGILSQDRVIDGQNLMPLLEGRASHSDHEFLFHYC 427
+ G V +E S +D+ PTL+ + G L + +DG +L PLL G S + LF Y
Sbjct: 237 HIAPG-VTHELASSLDLLPTLAALAGAPL-PNVTLDGFDLSPLLLG-TGKSPRQSLFFYP 293
Query: 428 GVYLHTVRWHQKDCATVWKAHYVTPKFYPEGTGACYGSGICSCSGDVTYHDPPLLFDISR 487
Y VR +KAH+ T T A C S +T H+PPLL+D+S+
Sbjct: 294 S-YPDEVRGVFAVRTGKYKAHFFTQGSAHSDTTA---DPACHASSSLTAHEPPLLYDLSK 349
Query: 488 DPSE 491
DP E
Sbjct: 350 DPGE 353
Score = 57.4 bits (137), Expect = 3e-08
Identities = 26/56 (46%), Positives = 35/56 (62%), Gaps = 4/56 (7%)
Query: 90 GGLPTNETTFAKLLQHRGYRTGLIGKWHLGLSCASRNDHCYHPLNHGFHYFYGVPF 145
GGLP E T A++L RGY TG+ GKWHLG+ + + P + GFH F G+P+
Sbjct: 14 GGLPLEEVTVAEVLAARGYLTGMAGKWHLGVG----PEGAFLPPHQGFHRFLGIPY 65
>gi|38569407 arylsulfatase B isoform 2 precursor [Homo sapiens]
Length = 413
Score = 87.4 bits (215), Expect = 3e-17
Identities = 52/140 (37%), Positives = 75/140 (53%), Gaps = 13/140 (9%)
Query: 7 PNIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRAAFLTGR 66
P++V L+ADDLG D+ +G+ + TP++D LA+ GV L + +CTPSR+ LTGR
Sbjct: 45 PHLVFLLADDLGWNDVGFHGSR-IRTPHLDALAAGGVLLDNYYTQP-LCTPSRSQLLTGR 102
Query: 67 YPIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGKWHLGLSCASRN 126
Y IR+G L W +P +E +LL+ GY T ++GKWHLG+
Sbjct: 103 YQIRTG------LQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGM----YR 152
Query: 127 DHCYHPLNHGFHYFYGVPFG 146
C P GF ++G G
Sbjct: 153 KECL-PTRRGFDTYFGYLLG 171
Score = 62.8 bits (151), Expect = 8e-10
Identities = 51/185 (27%), Positives = 75/185 (40%), Gaps = 15/185 (8%)
Query: 227 RNHEIIQQPMKEEKVASLMLKEALAFIERYKRE-PFLLFFSFLHVHTPL------ISKKK 279
R+ E + K ++ K A+A I + E P L+ + VH PL +
Sbjct: 197 RDGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYD 256
Query: 280 FVGRSKYGRYGDNVEEMDWMVGKILDALDQERLANHTLVYFTSDNGGHLEPLDGAVQLGG 339
F+ Y V MD VG + AL L N+T+ F++DNGG L G
Sbjct: 257 FIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQ--------TLAG 308
Query: 340 WNGIYKGGKGMGGWEGGIRVPGIFRWPSVLEAGRVINEPTSLMDIYPTLSYIGGGILSQD 399
N G+ WEGG+R G P + + G E + D PTL + G +
Sbjct: 309 GNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGT 368
Query: 400 RVIDG 404
+ +DG
Sbjct: 369 KPLDG 373
>gi|38569405 arylsulfatase B isoform 1 precursor [Homo sapiens]
Length = 533
Score = 87.4 bits (215), Expect = 3e-17
Identities = 52/140 (37%), Positives = 75/140 (53%), Gaps = 13/140 (9%)
Query: 7 PNIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRAAFLTGR 66
P++V L+ADDLG D+ +G+ + TP++D LA+ GV L + +CTPSR+ LTGR
Sbjct: 45 PHLVFLLADDLGWNDVGFHGSR-IRTPHLDALAAGGVLLDNYYTQP-LCTPSRSQLLTGR 102
Query: 67 YPIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGKWHLGLSCASRN 126
Y IR+G L W +P +E +LL+ GY T ++GKWHLG+
Sbjct: 103 YQIRTG------LQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGM----YR 152
Query: 127 DHCYHPLNHGFHYFYGVPFG 146
C P GF ++G G
Sbjct: 153 KECL-PTRRGFDTYFGYLLG 171
Score = 66.6 bits (161), Expect = 6e-11
Identities = 78/350 (22%), Positives = 130/350 (37%), Gaps = 50/350 (14%)
Query: 227 RNHEIIQQPMKEEKVASLMLKEALAFIERYKRE-PFLLFFSFLHVHTPL------ISKKK 279
R+ E + K ++ K A+A I + E P L+ + VH PL +
Sbjct: 197 RDGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYD 256
Query: 280 FVGRSKYGRYGDNVEEMDWMVGKILDALDQERLANHTLVYFTSDNGGHLEPLDGAVQLGG 339
F+ Y V MD VG + AL L N+T+ F++DNGG L G
Sbjct: 257 FIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQ--------TLAG 308
Query: 340 WNGIYKGGKGMGGWEGGIRVPGIFRWPSVLEAGRVINEPTSLMDIYPTLSYIGGGILSQD 399
N G+ WEGG+R G P + + G E + D PTL + G +
Sbjct: 309 GNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGT 368
Query: 400 RVIDGQNLMPLLEGRASHSDHEFLFHYCGVYLHTVRWHQKDCATVWKAHYVTPKFYPEGT 459
+ +DG ++ + + E L + ++ + + A K P++ T
Sbjct: 369 KPLDGFDVWKTISEGSPSPRIELLHNIDPNFVDSSPCPRNSMAPA-KDDSSLPEYSAFNT 427
Query: 460 GACYG---------SGICSCS-----------GDVTYHDPPL----LFDISRDPSEALPL 495
+G C ++ DPP LFDI RDP E L
Sbjct: 428 SVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSEIPSSDPPTKTLWLFDIDRDPEERHDL 487
Query: 496 NPDNEPLFDSVIKKMEAAIREHRRTLTPV------PQQFSVFNTIWKPWL 539
+ + + ++ K+ + ++ + + PV P+ +W PW+
Sbjct: 488 SRE----YPHIVTKLLSRLQFYHKHSVPVYFPAQDPRCDPKATGVWGPWM 533
>gi|109389362 arylsulfatase J [Homo sapiens]
Length = 599
Score = 84.3 bits (207), Expect = 3e-16
Identities = 49/145 (33%), Positives = 77/145 (53%), Gaps = 13/145 (8%)
Query: 2 TRNARPNIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRAA 61
T ++P+++ ++ADD G D+ +G+ + TP +D+LA+EGV+L + +CTPSR+
Sbjct: 71 TSTSQPHLIFILADDQGFRDVGYHGSE-IKTPTLDKLAAEGVKLENYYVQP-ICTPSRSQ 128
Query: 62 FLTGRYPIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGKWHLGLS 121
F+TG+Y I +G L + LP + T + L+ GY T ++GKWHLG
Sbjct: 129 FITGKYQIHTG------LQHSIIRPTQPNCLPLDNATLPQKLKEVGYSTHMVGKWHLGF- 181
Query: 122 CASRNDHCYHPLNHGFHYFYGVPFG 146
C P GF F+G G
Sbjct: 182 ---YRKECM-PTRRGFDTFFGSLLG 202
Score = 68.6 bits (166), Expect = 1e-11
Identities = 70/315 (22%), Positives = 125/315 (39%), Gaps = 52/315 (16%)
Query: 259 EPFLLFFSFLHVHTPLISKKKFVGRSKY------GRYGDNVEEMDWMVGKILDALDQERL 312
+P L+ ++ VH+PL + ++ + RY + +D + + AL
Sbjct: 257 KPIFLYIAYQAVHSPLQAPGRYFEHYRSIININRRRYAAMLSCLDEAINNVTLALKTYGF 316
Query: 313 ANHTLVYFTSDNGGHLEPLDGAVQLGGWNGIYKGGKGMGGWEGGIRVPGIFRWPSVLEAG 372
N++++ ++SDNGG GG N +G KG WEGGIR G P + G
Sbjct: 317 YNNSIIIYSSDNGGQ-------PTAGGSNWPLRGSKGTY-WEGGIRAVGFVHSPLLKNKG 368
Query: 373 RVINEPTSLMDIYPTLSYIGGGILSQDRVIDGQNLMPLLEGRASHSDHEFLFHYCGVYLH 432
V E + D YPTL + G + +D +DG ++ + + L + +Y
Sbjct: 369 TVCKELVHITDWYPTLISLAEGQIDEDIQLDGYDIWETISEGLRSPRVDILHNIDPIYTK 428
Query: 433 TVR---------WHQKDCATV----WK--------AHYVTPKFYPE-GTGACYGSGICSC 470
W+ + + WK + +V P+ + G + I
Sbjct: 429 AKNGSWAAGYGIWNTAIQSAIRVQHWKLLTGNPGYSDWVPPQSFSNLGPNRWHNERITLS 488
Query: 471 SGDVTYHDPPLLFDISRDPSEALPLNPDNEPLFDSVIKKMEAAIREHRRTLTPV------ 524
+G + LF+I+ DP E + L+ + ++KK+ + + +T PV
Sbjct: 489 TGKSVW-----LFNITADPYERVDLS----NRYPGIVKKLLRRLSQFNKTAVPVRYPPKD 539
Query: 525 PQQFSVFN-TIWKPW 538
P+ N +W PW
Sbjct: 540 PRSNPRLNGGVWGPW 554
>gi|59797060 arylsulfatase family, member I [Homo sapiens]
Length = 569
Score = 82.4 bits (202), Expect = 1e-15
Identities = 90/314 (28%), Positives = 128/314 (40%), Gaps = 49/314 (15%)
Query: 258 REPFLLFFSFLHVHTPLISKKKFV------GRSKYGRYGDNVEEMDWMVGKILDALDQER 311
+ P L+ +F VHTPL S ++++ G +Y V MD V I AL +
Sbjct: 226 QRPLFLYVAFQAVHTPLQSPREYLYRYRTMGNVARRKYAAMVTCMDEAVRNITWALKRYG 285
Query: 312 LANHTLVYFTSDNGGHLEPLDGAVQLGGWNGIYKGGKGMGGWEGGIRVPGIFRWPSVLEA 371
N++++ F+SDNGG GG N +G KG WEGG+R G P +
Sbjct: 286 FYNNSVIIFSSDNGGQTFS-------GGSNWPLRGRKGTY-WEGGVRGLGFVHSPLLKRK 337
Query: 372 GRVINEPTSLMDIYPTLSYIGGGILSQDRVIDGQNLMPLL-EGRASHSDHEFLFHYCGVY 430
R + D YPTL + GG S +DG ++ P + EGRAS E L + +Y
Sbjct: 338 QRTSRALMHITDWYPTLVGLAGGTTSAADGLDGYDVWPAISEGRASPRT-EILHNIDPLY 396
Query: 431 LHTVR---------WHQKDCATV----WKAHYVTPKF---YPEGTGACYGSGICSCSGDV 474
H W+ A + WK P + P T A + +
Sbjct: 397 NHAQHGSLEGGFGIWNTAVQAAIRVGEWKLLTGDPGYGDWIPPQTLATFPGSWWNLERMA 456
Query: 475 TYHDPPLLFDISRDPSEALPL---NPDNEPLFDSVIKKMEAAIREHRRTLTPV------P 525
+ LF+IS DP E L PD V++ + A + E+ RT PV P
Sbjct: 457 SVRQAVWLFNISADPYEREDLAGQRPD-------VVRTLLARLAEYNRTAIPVRYPAENP 509
Query: 526 QQFSVFN-TIWKPW 538
+ FN W PW
Sbjct: 510 RAHPDFNGGAWGPW 523
Score = 81.6 bits (200), Expect = 2e-15
Identities = 49/136 (36%), Positives = 72/136 (52%), Gaps = 13/136 (9%)
Query: 7 PNIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRAAFLTGR 66
P+I+ ++ DD G D+ +G++ + TP +DRLA++GV+L + +CTPSR+ LTGR
Sbjct: 47 PHIIFILTDDQGYHDVGYHGSD-IETPTLDRLAAKGVKLENYYIQP-ICTPSRSQLLTGR 104
Query: 67 YPIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGKWHLGLSCASRN 126
Y I +G L + LP ++ T + LQ GY T ++GKWHLG
Sbjct: 105 YQIHTG------LQHSIIRPQQPNCLPLDQVTLPQKLQEAGYSTHMVGKWHLGF----YR 154
Query: 127 DHCYHPLNHGFHYFYG 142
C P GF F G
Sbjct: 155 KECL-PTRRGFDTFLG 169
>gi|5360208 iduronate-2-sulfatase isoform b precursor [Homo sapiens]
Length = 343
Score = 65.1 bits (157), Expect = 2e-10
Identities = 43/124 (34%), Positives = 65/124 (52%), Gaps = 11/124 (8%)
Query: 8 NIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRAAFLTGRY 67
N++L++ DDL L CYG+ V +PNID+LAS + A ++C PSR +FLTGR
Sbjct: 38 NVLLIIVDDLRPS-LGCYGDKLVRSPNIDQLASHSLLFQNAFAQQAVCAPSRVSFLTGRR 96
Query: 68 PIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGK-WHLGLSCASRN 126
P + + Y+ N + G N +T + + GY T +GK +H G+S +
Sbjct: 97 PDTTRL---YDFNSYWRVHAG------NFSTIPQYFKENGYVTMSVGKVFHPGISSNHTD 147
Query: 127 DHCY 130
D Y
Sbjct: 148 DSPY 151
Score = 39.3 bits (90), Expect = 0.010
Identities = 18/37 (48%), Positives = 26/37 (70%)
Query: 289 YGDNVEEMDWMVGKILDALDQERLANHTLVYFTSDNG 325
Y +V +D VG++L ALD +LAN T++ FTSD+G
Sbjct: 300 YFASVSYLDTQVGRLLSALDDLQLANSTIIAFTSDHG 336
>gi|4557659 iduronate-2-sulfatase isoform a precursor [Homo sapiens]
Length = 550
Score = 65.1 bits (157), Expect = 2e-10
Identities = 43/124 (34%), Positives = 65/124 (52%), Gaps = 11/124 (8%)
Query: 8 NIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRAAFLTGRY 67
N++L++ DDL L CYG+ V +PNID+LAS + A ++C PSR +FLTGR
Sbjct: 38 NVLLIIVDDLRPS-LGCYGDKLVRSPNIDQLASHSLLFQNAFAQQAVCAPSRVSFLTGRR 96
Query: 68 PIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGK-WHLGLSCASRN 126
P + + Y+ N + G N +T + + GY T +GK +H G+S +
Sbjct: 97 PDTTRL---YDFNSYWRVHAG------NFSTIPQYFKENGYVTMSVGKVFHPGISSNHTD 147
Query: 127 DHCY 130
D Y
Sbjct: 148 DSPY 151
Score = 40.0 bits (92), Expect = 0.006
Identities = 33/116 (28%), Positives = 57/116 (49%), Gaps = 11/116 (9%)
Query: 289 YGDNVEEMDWMVGKILDALDQERLANHTLVYFTSDNGGHLEPLDGAVQLGGWNG------ 342
Y +V +D VG++L ALD +LAN T++ FTSD+G L + ++
Sbjct: 300 YFASVSYLDTQVGRLLSALDDLQLANSTIIAFTSDHGWALGEHGEWAKYSNFDVATHVPL 359
Query: 343 -IYKGGKGMGGWEGGIRV-PGIFRWPS---VLEAGRVINEPTSLMDIYPTLSYIGG 393
Y G+ E G ++ P + + S ++E GR + L+ ++PTL+ + G
Sbjct: 360 IFYVPGRTASLPEAGEKLFPYLDPFDSASQLMEPGRQSMDLVELVSLFPTLAGLAG 415
>gi|4506919 N-sulfoglucosamine sulfohydrolase precursor [Homo
sapiens]
Length = 502
Score = 64.3 bits (155), Expect = 3e-10
Identities = 44/127 (34%), Positives = 62/127 (48%), Gaps = 9/127 (7%)
Query: 5 ARP-NIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRAAFL 63
ARP N +LL+ADD G + Y N++++TP++D LA + + S C+PSRA+ L
Sbjct: 20 ARPRNALLLLADDGGF-ESGAYNNSAIATPHLDALARRSLLFRNAFTSVSSCSPSRASLL 78
Query: 64 TGRYPIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGKWHLGLSCA 123
TG ++GM + F LP LL G RTG+IGK H+G
Sbjct: 79 TGLPQHQNGMYGLHQDVHHFNSFDKVRSLPL-------LLSQAGVRTGIIGKKHVGPETV 131
Query: 124 SRNDHCY 130
D Y
Sbjct: 132 YPFDFAY 138
Score = 34.7 bits (78), Expect = 0.24
Identities = 43/148 (29%), Positives = 54/148 (36%), Gaps = 30/148 (20%)
Query: 293 VEEMDWMVGKILDALDQERLANHTLVYFTSDNGGHLEPLDGAVQLGGWNGIYKGGKGMGG 352
V MD VG +L L + N TLV FTSDNG G +Y G
Sbjct: 243 VGRMDQGVGLVLQELRDAGVLNDTLVIFTSDNGIPFP--------SGRTNLYWPGTAEPL 294
Query: 353 WEGGIRVPGIFRWPSVLEAGRVINEPTSLMDIYPT------LSYIGGGILSQDRV-IDGQ 405
P RW V EA SL+D+ PT + Y I + + G+
Sbjct: 295 LVSSPEHPK--RWGQVSEA------YVSLLDLTPTILDWFSIPYPSYAIFGSKTIHLTGR 346
Query: 406 NLMPLLEGR-------ASHSDHEFLFHY 426
+L+P LE S S HE Y
Sbjct: 347 SLLPALEAEPLWATVFGSQSHHEVTMSY 374
>gi|39930577 arylsulfatase K [Homo sapiens]
Length = 536
Score = 48.1 bits (113), Expect = 2e-05
Identities = 58/207 (28%), Positives = 86/207 (41%), Gaps = 53/207 (25%)
Query: 295 EMDWMVGKILDALDQERLANHTLVYFTSDNGGHLEPLDGAVQLGGWNGIYKGGKGMGGWE 354
E D M+G+I+ AL Q L T+V ++SD+G + A++ YK M +E
Sbjct: 285 ETDAMLGEIILALHQLDLLQKTIVIYSSDHG------ELAME---HRQFYK----MSMYE 331
Query: 355 GGIRVPGIFRWPSVLEAGRVINEPTSLMDIYPTLSYIGGGILSQDRVIDGQNLMPLLEGR 414
VP + P + +AG ++ SL+DIYPT+ I G L Q+ + G +L+PL
Sbjct: 332 ASAHVPLLMMGPGI-KAGLQVSNVVSLVDIYPTMLDIAGIPLPQN--LSGYSLLPL-SSE 387
Query: 415 ASHSDHEFL----------FHYCGVYLHTVRWHQKDCATVWKAHYVTPKFYPEGTGACYG 464
++H+ FH C V T WK Y+ Y +G
Sbjct: 388 TFKNEHKVKNLHPPWILSEFHGCNVNASTYMLRTNH----WK--YIA---YSDGASIL-- 436
Query: 465 SGICSCSGDVTYHDPPLLFDISRDPSE 491
P LFD+S DP E
Sbjct: 437 ---------------PQLFDLSSDPDE 448
Score = 42.0 bits (97), Expect = 0.001
Identities = 31/110 (28%), Positives = 53/110 (48%), Gaps = 14/110 (12%)
Query: 7 PNIVLLMADDLGVGDLCCY-GNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRAAFLTG 65
PN+VL+++D G L + G+ V P I+ + + G + +C PSRAA +G
Sbjct: 32 PNVVLVVSDSFD-GRLTFHPGSQVVKLPFINFMKTRGTSFLNAYTNSPICCPSRAAMWSG 90
Query: 66 RYPIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGK 115
+ + + ++N + GL N TT+ +++ GYRT GK
Sbjct: 91 LF---THLTESWNNFK---------GLDPNYTTWMDVMERHGYRTQKFGK 128
>gi|240255483 sulfatase 2 isoform a precursor [Homo sapiens]
Length = 870
Score = 47.4 bits (111), Expect = 4e-05
Identities = 35/114 (30%), Positives = 47/114 (41%), Gaps = 9/114 (7%)
Query: 3 RNARPNIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRAAF 62
RN RPNI+L++ DD V G+ V + G MC PSR++
Sbjct: 40 RNIRPNIILVLTDDQDVE----LGSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSI 95
Query: 63 LTGRYPIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGKW 116
LTG+Y + + N N + S TFA L GYRT GK+
Sbjct: 96 LTGKY-VHNHNTYTNNENCS----SPSWQAQHESRTFAVYLNSTGYRTAFFGKY 144
>gi|240255478 sulfatase 2 isoform b precursor [Homo sapiens]
Length = 867
Score = 47.4 bits (111), Expect = 4e-05
Identities = 35/114 (30%), Positives = 47/114 (41%), Gaps = 9/114 (7%)
Query: 3 RNARPNIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRAAF 62
RN RPNI+L++ DD V G+ V + G MC PSR++
Sbjct: 40 RNIRPNIILVLTDDQDVE----LGSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSI 95
Query: 63 LTGRYPIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGKW 116
LTG+Y + + N N + S TFA L GYRT GK+
Sbjct: 96 LTGKY-VHNHNTYTNNENCS----SPSWQAQHESRTFAVYLNSTGYRTAFFGKY 144
>gi|29789100 sulfatase 2 isoform a precursor [Homo sapiens]
Length = 870
Score = 47.4 bits (111), Expect = 4e-05
Identities = 35/114 (30%), Positives = 47/114 (41%), Gaps = 9/114 (7%)
Query: 3 RNARPNIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRAAF 62
RN RPNI+L++ DD V G+ V + G MC PSR++
Sbjct: 40 RNIRPNIILVLTDDQDVE----LGSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSI 95
Query: 63 LTGRYPIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGKW 116
LTG+Y + + N N + S TFA L GYRT GK+
Sbjct: 96 LTGKY-VHNHNTYTNNENCS----SPSWQAQHESRTFAVYLNSTGYRTAFFGKY 144
>gi|189571643 sulfatase 1 [Homo sapiens]
Length = 871
Score = 47.0 bits (110), Expect = 5e-05
Identities = 35/114 (30%), Positives = 49/114 (42%), Gaps = 9/114 (7%)
Query: 3 RNARPNIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRAAF 62
+N RPNI+L++ DD V G+ V + G MC PSR++
Sbjct: 39 KNIRPNIILVLTDDQDVE----LGSLQVMNKTRKIMEHGGATFINAFVTTPMCCPSRSSM 94
Query: 63 LTGRYPIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGKW 116
LTG+Y + + V N N + S TFA L + GYRT GK+
Sbjct: 95 LTGKY-VHNHNVYTNNENCS----SPSWQAMHEPRTFAVYLNNTGYRTAFFGKY 143
>gi|189571641 sulfatase 1 [Homo sapiens]
Length = 871
Score = 47.0 bits (110), Expect = 5e-05
Identities = 35/114 (30%), Positives = 49/114 (42%), Gaps = 9/114 (7%)
Query: 3 RNARPNIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRAAF 62
+N RPNI+L++ DD V G+ V + G MC PSR++
Sbjct: 39 KNIRPNIILVLTDDQDVE----LGSLQVMNKTRKIMEHGGATFINAFVTTPMCCPSRSSM 94
Query: 63 LTGRYPIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGKW 116
LTG+Y + + V N N + S TFA L + GYRT GK+
Sbjct: 95 LTGKY-VHNHNVYTNNENCS----SPSWQAMHEPRTFAVYLNNTGYRTAFFGKY 143
>gi|189571638 sulfatase 1 [Homo sapiens]
Length = 871
Score = 47.0 bits (110), Expect = 5e-05
Identities = 35/114 (30%), Positives = 49/114 (42%), Gaps = 9/114 (7%)
Query: 3 RNARPNIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRAAF 62
+N RPNI+L++ DD V G+ V + G MC PSR++
Sbjct: 39 KNIRPNIILVLTDDQDVE----LGSLQVMNKTRKIMEHGGATFINAFVTTPMCCPSRSSM 94
Query: 63 LTGRYPIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGKW 116
LTG+Y + + V N N + S TFA L + GYRT GK+
Sbjct: 95 LTGKY-VHNHNVYTNNENCS----SPSWQAMHEPRTFAVYLNNTGYRTAFFGKY 143
>gi|189571636 sulfatase 1 [Homo sapiens]
Length = 871
Score = 47.0 bits (110), Expect = 5e-05
Identities = 35/114 (30%), Positives = 49/114 (42%), Gaps = 9/114 (7%)
Query: 3 RNARPNIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRAAF 62
+N RPNI+L++ DD V G+ V + G MC PSR++
Sbjct: 39 KNIRPNIILVLTDDQDVE----LGSLQVMNKTRKIMEHGGATFINAFVTTPMCCPSRSSM 94
Query: 63 LTGRYPIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGKW 116
LTG+Y + + V N N + S TFA L + GYRT GK+
Sbjct: 95 LTGKY-VHNHNVYTNNENCS----SPSWQAMHEPRTFAVYLNNTGYRTAFFGKY 143
>gi|169217295 PREDICTED: similar to iduronate 2-sulfatase (Hunter
syndrome) [Homo sapiens]
Length = 142
Score = 45.8 bits (107), Expect = 1e-04
Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 9/86 (10%)
Query: 30 VSTPNIDRLASEGVRLTQHLAAASMCTPSRAAFLTGRYPIRSGMVSAYNLNRAFTWLGGS 89
V PNID+LAS + A ++C PSR +FLTGR P + + Y+ N + G
Sbjct: 22 VKAPNIDQLASHSLLFQNAFAQQAVCAPSRVSFLTGRRPDTTRL---YDFNSYWRVHAG- 77
Query: 90 GGLPTNETTFAKLLQHRGYRTGLIGK 115
N +T + + GY T +GK
Sbjct: 78 -----NFSTIPQYFKENGYVTMSVGK 98
>gi|4504061 glucosamine (N-acetyl)-6-sulfatase precursor [Homo
sapiens]
Length = 552
Score = 38.9 bits (89), Expect = 0.013
Identities = 34/125 (27%), Positives = 63/125 (50%), Gaps = 22/125 (17%)
Query: 296 MDWMVGKILDALDQERLANHTLVYFTSDNGGHLE----PLDGAVQLGGWNGIYKGGKGMG 351
+D +V K++ L+ N+T +++TSDNG H P+D QL
Sbjct: 299 VDDLVEKLVKRLEFTGELNNTYIFYTSDNGYHTGQFSLPIDKR-QL-------------- 343
Query: 352 GWEGGIRVPGIFRWPSVLEAGRVINEPTSLMDIYPTLSYIGGGILSQDRVIDGQNLMPLL 411
+E I+VP + R P + + + + +D+ PT+ I G L++ + +DG +L+P+L
Sbjct: 344 -YEFDIKVPLLVRGPGI-KPNQTSKMLVANIDLGPTILDIAGYDLNKTQ-MDGMSLLPIL 400
Query: 412 EGRAS 416
G ++
Sbjct: 401 RGASN 405
Score = 37.4 bits (85), Expect = 0.037
Identities = 39/141 (27%), Positives = 59/141 (41%), Gaps = 14/141 (9%)
Query: 6 RPNIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRAAFLTG 65
RPN+VLL+ DD G + + G+ + +++C PSRA+ LTG
Sbjct: 46 RPNVVLLLTDDQDE----VLGGMTPLKKTKALIGEMGMTFSSAYVPSALCCPSRASILTG 101
Query: 66 RYPIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHR-GYRTGLIGKW--HLGLSC 122
+YP +V N S TF +L+ GY+T GK+ G
Sbjct: 102 KYPHNHHVV---NNTLEGNCSSKSWQKIQEPNTFPAILRSMCGYQTFFAGKYLNEYGAPD 158
Query: 123 ASRNDHCYHPLNHGFHYFYGV 143
A +H PL G+ Y+Y +
Sbjct: 159 AGGLEHV--PL--GWSYWYAL 175
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.141 0.470
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,363,922
Number of Sequences: 37866
Number of extensions: 1122383
Number of successful extensions: 3154
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 3019
Number of HSP's gapped (non-prelim): 74
length of query: 562
length of database: 18,247,518
effective HSP length: 107
effective length of query: 455
effective length of database: 14,195,856
effective search space: 6459114480
effective search space used: 6459114480
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.