Search of human proteins with 58331246

Search of human proteins with 58331246

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|58331246 glutamate decarboxylase 1 isoform GAD67 [Homo
sapiens]
         (594 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|58331246 glutamate decarboxylase 1 isoform GAD67 [Homo sapiens]   1213   0.0  
gi|197276620 glutamate decarboxylase 2 [Homo sapiens]                 783   0.0  
gi|4503875 glutamate decarboxylase 2 [Homo sapiens]                   783   0.0  
gi|194294551 cysteine sulfinic acid decarboxylase [Homo sapiens]      528   e-150
gi|197383062 glutamate decarboxylase-like 1 [Homo sapiens]            514   e-146
gi|15451889 glutamate decarboxylase 1 isoform GAD25 [Homo sapiens]    433   e-121
gi|132814448 dopa decarboxylase (aromatic L-amino acid decarboxy...   139   6e-33
gi|4503281 dopa decarboxylase (aromatic L-amino acid decarboxyla...   139   6e-33
gi|92110055 histidine decarboxylase [Homo sapiens]                    123   4e-28
gi|190341074 pyridoxal-dependent decarboxylase domain containing...    47   4e-05
gi|31982936 sphingosine-1-phosphate lyase 1 [Homo sapiens]             37   0.051
gi|87298937 centrosomal protein 110kDa [Homo sapiens]                  30   4.8  
gi|68299759 ecotropic viral integration site 5 [Homo sapiens]          30   8.2  
gi|33620755 YEATS domain containing 2 [Homo sapiens]                   30   8.2  

>gi|58331246 glutamate decarboxylase 1 isoform GAD67 [Homo sapiens]
          Length = 594

 Score = 1213 bits (3138), Expect = 0.0
 Identities = 594/594 (100%), Positives = 594/594 (100%)

Query: 1   MASSTPSSSATSSNAGADPNTTNLRPTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEK 60
           MASSTPSSSATSSNAGADPNTTNLRPTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEK
Sbjct: 1   MASSTPSSSATSSNAGADPNTTNLRPTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEK 60

Query: 61  SRLVSAFKERQSSKNLLSCENSDRDARFRRTETDFSNLFARDLLPAKNGEEQTVQFLLEV 120
           SRLVSAFKERQSSKNLLSCENSDRDARFRRTETDFSNLFARDLLPAKNGEEQTVQFLLEV
Sbjct: 61  SRLVSAFKERQSSKNLLSCENSDRDARFRRTETDFSNLFARDLLPAKNGEEQTVQFLLEV 120

Query: 121 VDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGV 180
           VDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGV
Sbjct: 121 VDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGV 180

Query: 181 RTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQITLKKMREIVGWS 240
           RTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQITLKKMREIVGWS
Sbjct: 181 RTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQITLKKMREIVGWS 240

Query: 241 SKDGDGIFSPGGAISNMYSIMAARYKYFPEVKTKGMAAVPKLVLFTSEQSHYSIKKAGAA 300
           SKDGDGIFSPGGAISNMYSIMAARYKYFPEVKTKGMAAVPKLVLFTSEQSHYSIKKAGAA
Sbjct: 241 SKDGDGIFSPGGAISNMYSIMAARYKYFPEVKTKGMAAVPKLVLFTSEQSHYSIKKAGAA 300

Query: 301 LGFGTDNVILIKCNERGKIIPADFEAKILEAKQKGYVPFYVNATAGTTVYGAFDPIQEIA 360
           LGFGTDNVILIKCNERGKIIPADFEAKILEAKQKGYVPFYVNATAGTTVYGAFDPIQEIA
Sbjct: 301 LGFGTDNVILIKCNERGKIIPADFEAKILEAKQKGYVPFYVNATAGTTVYGAFDPIQEIA 360

Query: 361 DICEKYNLWLHVDAAWGGGLLMSRKHRHKLNGIERANSVTWNPHKMMGVLLQCSAILVKE 420
           DICEKYNLWLHVDAAWGGGLLMSRKHRHKLNGIERANSVTWNPHKMMGVLLQCSAILVKE
Sbjct: 361 DICEKYNLWLHVDAAWGGGLLMSRKHRHKLNGIERANSVTWNPHKMMGVLLQCSAILVKE 420

Query: 421 KGILQGCNQMCAGYLFQPDKQYDVSYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQI 480
           KGILQGCNQMCAGYLFQPDKQYDVSYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQI
Sbjct: 421 KGILQGCNQMCAGYLFQPDKQYDVSYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQI 480

Query: 481 NKCLELAEYLYAKIKNREEFEMVFNGEPEHTNVCFWYIPQSLRGVPDSPQRREKLHKVAP 540
           NKCLELAEYLYAKIKNREEFEMVFNGEPEHTNVCFWYIPQSLRGVPDSPQRREKLHKVAP
Sbjct: 481 NKCLELAEYLYAKIKNREEFEMVFNGEPEHTNVCFWYIPQSLRGVPDSPQRREKLHKVAP 540

Query: 541 KIKALMMESGTTMVGYQPQGDKANFFRMVISNPAATQSDIDFLIEEIERLGQDL 594
           KIKALMMESGTTMVGYQPQGDKANFFRMVISNPAATQSDIDFLIEEIERLGQDL
Sbjct: 541 KIKALMMESGTTMVGYQPQGDKANFFRMVISNPAATQSDIDFLIEEIERLGQDL 594


>gi|197276620 glutamate decarboxylase 2 [Homo sapiens]
          Length = 585

 Score =  783 bits (2023), Expect = 0.0
 Identities = 375/569 (65%), Positives = 457/569 (80%), Gaps = 6/569 (1%)

Query: 26  PTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEKSRLVSAFKERQSSKNLLSCENSDRD 85
           P T   WC VA   T  +G K+C  L       EK       +  +++    +C    + 
Sbjct: 23  PGTARAWCQVAQKFTGGIGNKLCALLYGD---AEKPAESGGSQPPRAAARKAACACDQKP 79

Query: 86  ARFRRTETDFSNLFARDLLPAKNGEEQTVQFLLEVVDILLNYVRKTFDRSTKVLDFHHPH 145
               + + +++ L A DLLPA +GE  T+ FL +V++ILL YV K+FDRSTKV+DFH+P+
Sbjct: 80  CSCSKVDVNYAFLHATDLLPACDGERPTLAFLQDVMNILLQYVVKSFDRSTKVIDFHYPN 139

Query: 146 QLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGVRTGHPRFFNQLSTGLDIIGLAGEWL 205
           +LL+    +N EL+D P++LE+IL+ C+ TLKY ++TGHPR+FNQLSTGLD++GLA +WL
Sbjct: 140 ELLQE---YNWELADQPQNLEEILMHCQTTLKYAIKTGHPRYFNQLSTGLDMVGLAADWL 196

Query: 206 TSTANTNMFTYEIAPVFVLMEQITLKKMREIVGWSSKDGDGIFSPGGAISNMYSIMAARY 265
           TSTANTNMFTYEIAPVFVL+E +TLKKMREI+GW    GDGIFSPGGAISNMY++M AR+
Sbjct: 197 TSTANTNMFTYEIAPVFVLLEYVTLKKMREIIGWPGGSGDGIFSPGGAISNMYAMMIARF 256

Query: 266 KYFPEVKTKGMAAVPKLVLFTSEQSHYSIKKAGAALGFGTDNVILIKCNERGKIIPADFE 325
           K FPEVK KGMAA+P+L+ FTSE SH+S+KK  AALG GTD+VILIKC+ERGK+IP+D E
Sbjct: 257 KMFPEVKEKGMAALPRLIAFTSEHSHFSLKKGAAALGIGTDSVILIKCDERGKMIPSDLE 316

Query: 326 AKILEAKQKGYVPFYVNATAGTTVYGAFDPIQEIADICEKYNLWLHVDAAWGGGLLMSRK 385
            +ILEAKQKG+VPF V+ATAGTTVYGAFDP+  +ADIC+KY +W+HVDAAWGGGLLMSRK
Sbjct: 317 RRILEAKQKGFVPFLVSATAGTTVYGAFDPLLAVADICKKYKIWMHVDAAWGGGLLMSRK 376

Query: 386 HRHKLNGIERANSVTWNPHKMMGVLLQCSAILVKEKGILQGCNQMCAGYLFQPDKQYDVS 445
           H+ KL+G+ERANSVTWNPHKMMGV LQCSA+LV+E+G++Q CNQM A YLFQ DK YD+S
Sbjct: 377 HKWKLSGVERANSVTWNPHKMMGVPLQCSALLVREEGLMQNCNQMHASYLFQQDKHYDLS 436

Query: 446 YDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQINKCLELAEYLYAKIKNREEFEMVFN 505
           YDTGDKA+QCGRHVD+FK WLMW+AKGT GFE  ++KCLELAEYLY  IKNRE +EMVF+
Sbjct: 437 YDTGDKALQCGRHVDVFKLWLMWRAKGTTGFEAHVDKCLELAEYLYNIIKNREGYEMVFD 496

Query: 506 GEPEHTNVCFWYIPQSLRGVPDSPQRREKLHKVAPKIKALMMESGTTMVGYQPQGDKANF 565
           G+P+HTNVCFWYIP SLR + D+ +R  +L KVAP IKA MME GTTMV YQP GDK NF
Sbjct: 497 GKPQHTNVCFWYIPPSLRTLEDNEERMSRLSKVAPVIKARMMEYGTTMVSYQPLGDKVNF 556

Query: 566 FRMVISNPAATQSDIDFLIEEIERLGQDL 594
           FRMVISNPAAT  DIDFLIEEIERLGQDL
Sbjct: 557 FRMVISNPAATHQDIDFLIEEIERLGQDL 585


>gi|4503875 glutamate decarboxylase 2 [Homo sapiens]
          Length = 585

 Score =  783 bits (2023), Expect = 0.0
 Identities = 375/569 (65%), Positives = 457/569 (80%), Gaps = 6/569 (1%)

Query: 26  PTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEKSRLVSAFKERQSSKNLLSCENSDRD 85
           P T   WC VA   T  +G K+C  L       EK       +  +++    +C    + 
Sbjct: 23  PGTARAWCQVAQKFTGGIGNKLCALLYGD---AEKPAESGGSQPPRAAARKAACACDQKP 79

Query: 86  ARFRRTETDFSNLFARDLLPAKNGEEQTVQFLLEVVDILLNYVRKTFDRSTKVLDFHHPH 145
               + + +++ L A DLLPA +GE  T+ FL +V++ILL YV K+FDRSTKV+DFH+P+
Sbjct: 80  CSCSKVDVNYAFLHATDLLPACDGERPTLAFLQDVMNILLQYVVKSFDRSTKVIDFHYPN 139

Query: 146 QLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGVRTGHPRFFNQLSTGLDIIGLAGEWL 205
           +LL+    +N EL+D P++LE+IL+ C+ TLKY ++TGHPR+FNQLSTGLD++GLA +WL
Sbjct: 140 ELLQE---YNWELADQPQNLEEILMHCQTTLKYAIKTGHPRYFNQLSTGLDMVGLAADWL 196

Query: 206 TSTANTNMFTYEIAPVFVLMEQITLKKMREIVGWSSKDGDGIFSPGGAISNMYSIMAARY 265
           TSTANTNMFTYEIAPVFVL+E +TLKKMREI+GW    GDGIFSPGGAISNMY++M AR+
Sbjct: 197 TSTANTNMFTYEIAPVFVLLEYVTLKKMREIIGWPGGSGDGIFSPGGAISNMYAMMIARF 256

Query: 266 KYFPEVKTKGMAAVPKLVLFTSEQSHYSIKKAGAALGFGTDNVILIKCNERGKIIPADFE 325
           K FPEVK KGMAA+P+L+ FTSE SH+S+KK  AALG GTD+VILIKC+ERGK+IP+D E
Sbjct: 257 KMFPEVKEKGMAALPRLIAFTSEHSHFSLKKGAAALGIGTDSVILIKCDERGKMIPSDLE 316

Query: 326 AKILEAKQKGYVPFYVNATAGTTVYGAFDPIQEIADICEKYNLWLHVDAAWGGGLLMSRK 385
            +ILEAKQKG+VPF V+ATAGTTVYGAFDP+  +ADIC+KY +W+HVDAAWGGGLLMSRK
Sbjct: 317 RRILEAKQKGFVPFLVSATAGTTVYGAFDPLLAVADICKKYKIWMHVDAAWGGGLLMSRK 376

Query: 386 HRHKLNGIERANSVTWNPHKMMGVLLQCSAILVKEKGILQGCNQMCAGYLFQPDKQYDVS 445
           H+ KL+G+ERANSVTWNPHKMMGV LQCSA+LV+E+G++Q CNQM A YLFQ DK YD+S
Sbjct: 377 HKWKLSGVERANSVTWNPHKMMGVPLQCSALLVREEGLMQNCNQMHASYLFQQDKHYDLS 436

Query: 446 YDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQINKCLELAEYLYAKIKNREEFEMVFN 505
           YDTGDKA+QCGRHVD+FK WLMW+AKGT GFE  ++KCLELAEYLY  IKNRE +EMVF+
Sbjct: 437 YDTGDKALQCGRHVDVFKLWLMWRAKGTTGFEAHVDKCLELAEYLYNIIKNREGYEMVFD 496

Query: 506 GEPEHTNVCFWYIPQSLRGVPDSPQRREKLHKVAPKIKALMMESGTTMVGYQPQGDKANF 565
           G+P+HTNVCFWYIP SLR + D+ +R  +L KVAP IKA MME GTTMV YQP GDK NF
Sbjct: 497 GKPQHTNVCFWYIPPSLRTLEDNEERMSRLSKVAPVIKARMMEYGTTMVSYQPLGDKVNF 556

Query: 566 FRMVISNPAATQSDIDFLIEEIERLGQDL 594
           FRMVISNPAAT  DIDFLIEEIERLGQDL
Sbjct: 557 FRMVISNPAATHQDIDFLIEEIERLGQDL 585


>gi|194294551 cysteine sulfinic acid decarboxylase [Homo sapiens]
          Length = 520

 Score =  528 bits (1359), Expect = e-150
 Identities = 259/496 (52%), Positives = 356/496 (71%), Gaps = 10/496 (2%)

Query: 102 DLLPAKNGEEQTVQFLLEVVD--ILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELS 159
           + LP+  G+   V+ LL  V   ++   ++K    S KV ++  P +L + ++   LEL 
Sbjct: 32  EALPSLAGDPVAVEALLRAVFGVVVDEAIQKGTSVSQKVCEWKEPEELKQLLD---LELR 88

Query: 160 DHPESLEQILVDCRDTLKYGVRTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIA 219
              ES +QIL  CR  ++Y V+TGHPRFFNQL +GLD   LAG  +T + NT+ +TYEIA
Sbjct: 89  SQGESQKQILERCRAVIRYSVKTGHPRFFNQLFSGLDPHALAGRIITESLNTSQYTYEIA 148

Query: 220 PVFVLMEQITLKKMREIVGWSSKDGDGIFSPGGAISNMYSIMAARYKYFPEVKTKGMAAV 279
           PVFVLME+  L+K+R +VGWSS  GDGIF PGG+ISNMY++  ARY+ +P+ K +G+  +
Sbjct: 149 PVFVLMEEEVLRKLRALVGWSS--GDGIFCPGGSISNMYAVNLARYQRYPDCKQRGLRTL 206

Query: 280 PKLVLFTSEQSHYSIKKAGAALGFGTDNVILIKCNERGKIIPADFEAKILEAKQKGYVPF 339
           P L LFTS++ HYSI+K  A LG GTD+V ++K +ERGK++P D E +I  A+ +G VPF
Sbjct: 207 PPLALFTSKECHYSIQKGAAFLGLGTDSVRVVKADERGKMVPEDLERQIGMAEAEGAVPF 266

Query: 340 YVNATAGTTVYGAFDPIQEIADICEKYNLWLHVDAAWGGGLLMSRKHRHKLNGIERANSV 399
            V+AT+GTTV GAFDP++ IAD+C+++ LWLHVDAAWGG +L+S+ HRH L+GI+RA+SV
Sbjct: 267 LVSATSGTTVLGAFDPLEAIADVCQRHGLWLHVDAAWGGSVLLSQTHRHLLDGIQRADSV 326

Query: 400 TWNPHKMMGVLLQCSAILVKE-KGILQGCNQMCAGYLFQPDKQYDVSYDTGDKAIQCGRH 458
            WNPHK++   LQCSA+L+++   +L+ C+   A YLFQ DK YDV+ DTGDK +QCGR 
Sbjct: 327 AWNPHKLLAAGLQCSALLLQDTSNLLKRCHGSQASYLFQQDKFYDVALDTGDKVVQCGRR 386

Query: 459 VDIFKFWLMWKAKGTVGFENQINKCLELAEYLYAKIKNREEFEMVFNGEPEHTNVCFWYI 518
           VD  K WLMWKA+G  G E +I++   LA YL  ++K RE FE+V   EPE  NVCFW++
Sbjct: 387 VDCLKLWLMWKAQGDQGLERRIDQAFVLARYLVEEMKKREGFELVM--EPEFVNVCFWFV 444

Query: 519 PQSLRGVPDSPQRREKLHKVAPKIKALMMESGTTMVGYQPQGDKANFFRMVISNPAATQS 578
           P SLRG  +SP   E+L KVAP +K  M++ G+ M+GYQP G + NFFR+V++N A T +
Sbjct: 445 PPSLRGKQESPDYHERLSKVAPVLKERMVKEGSMMIGYQPHGTRGNFFRVVVANSALTCA 504

Query: 579 DIDFLIEEIERLGQDL 594
           D+DFL+ E+ERLGQDL
Sbjct: 505 DMDFLLNELERLGQDL 520


>gi|197383062 glutamate decarboxylase-like 1 [Homo sapiens]
          Length = 521

 Score =  514 bits (1325), Expect = e-146
 Identities = 251/493 (50%), Positives = 348/493 (70%), Gaps = 17/493 (3%)

Query: 106 AKNGE---EQTVQFLLEVVDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHP 162
           AK GE   E+  + ++E V      V K  D + KV ++  P QL + ++   LE+ D  
Sbjct: 42  AKAGEKFVEEACRLIMEEV------VLKATDVNEKVCEWRPPEQLKQLLD---LEMRDSG 92

Query: 163 ESLEQILVDCRDTLKYGVRTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAPVF 222
           E   ++L  CRD + Y V+T HPRFFNQL  GLD   L   ++T   N +++TYE++PVF
Sbjct: 93  EPPHKLLELCRDVIHYSVKTNHPRFFNQLYAGLDYYSLVARFMTEALNPSVYTYEVSPVF 152

Query: 223 VLMEQITLKKMREIVGWSSKDGDGIFSPGGAISNMYSIMAARYKYFPEVKTKGMAAVPKL 282
           +L+E+  LKKM E +GW  K+GDGIF+PGG++SNMY++  ARYKY P++K KG++  P+L
Sbjct: 153 LLVEEAVLKKMIEFIGW--KEGDGIFNPGGSVSNMYAMNLARYKYCPDIKEKGLSGSPRL 210

Query: 283 VLFTSEQSHYSIKKAGAALGFGTDNVILIKCNERGKIIPADFEAKILEAKQKGYVPFYVN 342
           +LFTS + HYS+KKA + LG GT+NV  ++ + RGK+IP + E ++ +A+++G  PF V 
Sbjct: 211 ILFTSAECHYSMKKAASFLGIGTENVCFVETDGRGKMIPEELEKQVWQARKEGAAPFLVC 270

Query: 343 ATAGTTVYGAFDPIQEIADICEKYNLWLHVDAAWGGGLLMSRKHRHKLNGIERANSVTWN 402
           AT+GTTV GAFDP+ EIADICE+++LWLHVDA+WGG  LMSRKHR  L+GI RA+SV WN
Sbjct: 271 ATSGTTVLGAFDPLDEIADICERHSLWLHVDASWGGSALMSRKHRKLLHGIHRADSVAWN 330

Query: 403 PHKMMGVLLQCSAILVKEKG-ILQGCNQMCAGYLFQPDKQYDVSYDTGDKAIQCGRHVDI 461
           PHKM+   +QC A+LVK+K  +L+ C    A YLFQ DK YDVSYDTGDK+IQC R  D 
Sbjct: 331 PHKMLMAGIQCCALLVKDKSDLLKKCYSAKASYLFQQDKFYDVSYDTGDKSIQCSRRPDA 390

Query: 462 FKFWLMWKAKGTVGFENQINKCLELAEYLYAKIKNREEFEMVFNGEPEHTNVCFWYIPQS 521
           FKFW+ WKA GT+G E ++N+ L L+ YL  +IK RE F+++   EPE+ N+CFWYIP S
Sbjct: 391 FKFWMTWKALGTLGLEERVNRALALSRYLVDEIKKREGFKLLM--EPEYANICFWYIPPS 448

Query: 522 LRGVPDSPQRREKLHKVAPKIKALMMESGTTMVGYQPQGDKANFFRMVISNPAATQSDID 581
           LR + + P+   KL+ VAP IK  MM+ G+ M+GYQP   K NFFR V+ +P  ++ D+D
Sbjct: 449 LREMEEGPEFWAKLNLVAPAIKERMMKKGSLMLGYQPHRGKVNFFRQVVISPQVSREDMD 508

Query: 582 FLIEEIERLGQDL 594
           FL++EI+ LG+D+
Sbjct: 509 FLLDEIDLLGKDM 521


>gi|15451889 glutamate decarboxylase 1 isoform GAD25 [Homo sapiens]
          Length = 224

 Score =  433 bits (1113), Expect = e-121
 Identities = 213/213 (100%), Positives = 213/213 (100%)

Query: 1   MASSTPSSSATSSNAGADPNTTNLRPTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEK 60
           MASSTPSSSATSSNAGADPNTTNLRPTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEK
Sbjct: 1   MASSTPSSSATSSNAGADPNTTNLRPTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEK 60

Query: 61  SRLVSAFKERQSSKNLLSCENSDRDARFRRTETDFSNLFARDLLPAKNGEEQTVQFLLEV 120
           SRLVSAFKERQSSKNLLSCENSDRDARFRRTETDFSNLFARDLLPAKNGEEQTVQFLLEV
Sbjct: 61  SRLVSAFKERQSSKNLLSCENSDRDARFRRTETDFSNLFARDLLPAKNGEEQTVQFLLEV 120

Query: 121 VDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGV 180
           VDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGV
Sbjct: 121 VDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGV 180

Query: 181 RTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNM 213
           RTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNM
Sbjct: 181 RTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNM 213


>gi|132814448 dopa decarboxylase (aromatic L-amino acid
           decarboxylase) [Homo sapiens]
          Length = 480

 Score =  139 bits (351), Expect = 6e-33
 Identities = 98/363 (26%), Positives = 167/363 (46%), Gaps = 34/363 (9%)

Query: 162 PESLEQILVDCRDTLKYGVRTGH-PRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAP 220
           P++ E I+ D    +  GV   H P FF    T      +  + L        F++  +P
Sbjct: 50  PDTFEDIINDVEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASP 109

Query: 221 VFVLMEQIT---LKKMREI----VGWSSKDGDGIFSPGGAISNMYSIMAARYKYFPEVKT 273
               +E +    L KM E+    +   + +G G+     + + + +++AAR K    ++ 
Sbjct: 110 ACTELETVMMDWLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQA 169

Query: 274 KG-----MAAVPKLVLFTSEQSHYSIKKAGAALGFGTDNVILIKCNERGKIIPAD----- 323
                   A + KLV ++S+Q+H S+++AG   G             + K IP+D     
Sbjct: 170 ASPELTQAAIMEKLVAYSSDQAHSSVERAGLIGGV------------KLKAIPSDGNFAM 217

Query: 324 ----FEAKILEAKQKGYVPFYVNATAGTTVYGAFDPIQEIADICEKYNLWLHVDAAWGGG 379
                +  +   K  G +PF++ AT GTT   +FD + E+  IC K ++WLHVDAA+ G 
Sbjct: 218 RASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGS 277

Query: 380 LLMSRKHRHKLNGIERANSVTWNPHKMMGVLLQCSAILVKEKGILQGCNQMCAGYLFQPD 439
             +  + RH LNG+E A+S  +NPHK + V   CSA+ VK++  L G  ++   YL    
Sbjct: 278 AFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSH 337

Query: 440 KQYDVSYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQINKCLELAEYLYAKIKNREE 499
           +   +  D     I  GR     K W +++  G  G +  I K ++L+    + ++    
Sbjct: 338 QDSGLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPR 397

Query: 500 FEM 502
           FE+
Sbjct: 398 FEI 400


>gi|4503281 dopa decarboxylase (aromatic L-amino acid decarboxylase)
           [Homo sapiens]
          Length = 480

 Score =  139 bits (351), Expect = 6e-33
 Identities = 98/363 (26%), Positives = 167/363 (46%), Gaps = 34/363 (9%)

Query: 162 PESLEQILVDCRDTLKYGVRTGH-PRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAP 220
           P++ E I+ D    +  GV   H P FF    T      +  + L        F++  +P
Sbjct: 50  PDTFEDIINDVEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASP 109

Query: 221 VFVLMEQIT---LKKMREI----VGWSSKDGDGIFSPGGAISNMYSIMAARYKYFPEVKT 273
               +E +    L KM E+    +   + +G G+     + + + +++AAR K    ++ 
Sbjct: 110 ACTELETVMMDWLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQA 169

Query: 274 KG-----MAAVPKLVLFTSEQSHYSIKKAGAALGFGTDNVILIKCNERGKIIPAD----- 323
                   A + KLV ++S+Q+H S+++AG   G             + K IP+D     
Sbjct: 170 ASPELTQAAIMEKLVAYSSDQAHSSVERAGLIGGV------------KLKAIPSDGNFAM 217

Query: 324 ----FEAKILEAKQKGYVPFYVNATAGTTVYGAFDPIQEIADICEKYNLWLHVDAAWGGG 379
                +  +   K  G +PF++ AT GTT   +FD + E+  IC K ++WLHVDAA+ G 
Sbjct: 218 RASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGS 277

Query: 380 LLMSRKHRHKLNGIERANSVTWNPHKMMGVLLQCSAILVKEKGILQGCNQMCAGYLFQPD 439
             +  + RH LNG+E A+S  +NPHK + V   CSA+ VK++  L G  ++   YL    
Sbjct: 278 AFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSH 337

Query: 440 KQYDVSYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQINKCLELAEYLYAKIKNREE 499
           +   +  D     I  GR     K W +++  G  G +  I K ++L+    + ++    
Sbjct: 338 QDSGLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPR 397

Query: 500 FEM 502
           FE+
Sbjct: 398 FEI 400


>gi|92110055 histidine decarboxylase [Homo sapiens]
          Length = 662

 Score =  123 bits (309), Expect = 4e-28
 Identities = 103/368 (27%), Positives = 163/368 (44%), Gaps = 41/368 (11%)

Query: 160 DHPESLEQILVDCRDTLKYGV---RTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTY 216
           + P+S + I  D    +  GV   ++ H   +    T      L G+ L    N   FT+
Sbjct: 49  EDPDSWDSIFGDIERIIMPGVVHWQSPHMHAYYPALTSWP--SLLGDMLADAINCLGFTW 106

Query: 217 EIAPVFVLMEQITLKKMREIVGWS--------SKDGDGIFSPGGAISNMYSIMAARYKYF 268
             +P    +E   +  + +++G          S  G G+     + S + +++AAR    
Sbjct: 107 ASSPACTELEMNVMDWLAKMLGLPEHFLHHHPSSQGGGVLQSTVSESTLIALLAARKNKI 166

Query: 269 PEVKTKGMAAVP-----KLVLFTSEQSHYSIKKAGAALGFGTDNVILIKCNERGKIIPAD 323
            E+KT    A       +LV + S+Q+H S++KAG         + L+K     K +P D
Sbjct: 167 LEMKTSEPDADESCLNARLVAYASDQAHSSVEKAGL--------ISLVKM----KFLPVD 214

Query: 324 ---------FEAKILEAKQKGYVPFYVNATAGTTVYGAFDPIQEIADICEKYNLWLHVDA 374
                     +  I E KQ+G VP +V AT GTT   AFD + E+  IC +  LWLH+DA
Sbjct: 215 DNFSLRGEALQKAIEEDKQRGLVPVFVCATLGTTGVCAFDCLSELGPICAREGLWLHIDA 274

Query: 375 AWGGGLLMSRKHRHKLNGIERANSVTWNPHKMMGVLLQCSAILVKEKGILQGCNQMCAGY 434
           A+ G   +  + R  L GIE A+S T+NP K M V   C+   VK+K  LQ    +   Y
Sbjct: 275 AYAGTAFLCPEFRGFLKGIEYADSFTFNPSKWMMVHFDCTGFWVKDKYKLQQTFSVNPIY 334

Query: 435 LFQPDKQYDVSYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQINKCLELAEYLYAKI 494
           L   +    V+ D     I   R     K W + ++ G    +  +    E+A+Y  + +
Sbjct: 335 LRHANS--GVATDFMHWQIPLSRRFRSVKLWFVIRSFGVKNLQAHVRHGTEMAKYFESLV 392

Query: 495 KNREEFEM 502
           +N   FE+
Sbjct: 393 RNDPSFEI 400


>gi|190341074 pyridoxal-dependent decarboxylase domain containing 1
           [Homo sapiens]
          Length = 788

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 65/285 (22%), Positives = 116/285 (40%), Gaps = 38/285 (13%)

Query: 322 ADFEAKILEAKQKGYVPFYVNATAGTTVYGAFDPIQEIADICEKYNLWLHVDAAWGGGLL 381
           A  E  I +  ++G +P  + A AGT   G  D I  + ++CE+Y +WLHV+      L 
Sbjct: 219 AFLEKLIKDDIERGRLPLLLVANAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLA 278

Query: 382 MSRKHRHKLNGIERANSVTWNPHKMMGVLLQCSAILVKEKGILQGCNQMCAGYLFQPDKQ 441
           +       L    + +S+T  P   +G+    +  L K          + AG        
Sbjct: 279 LGYVSSSVL-AAAKCDSMTMTPGPWLGLPAVPAVTLYKHD---DPALTLVAGL------- 327

Query: 442 YDVSYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQINKCLELAEYLYAKIKNREEFE 501
                 T +K     R + +   WL  +  G  GF  +I    +L++ L   +K     +
Sbjct: 328 ------TSNKPTDKLRALPL---WLSLQYLGLDGFVERIKHACQLSQRLQESLKKVNYIK 378

Query: 502 MVFNGEPEHTNVCFWY---IPQS---LRGVP-----DSPQRREK-----LHK-VAPKIKA 544
           ++   E     V F +   +P S    + VP      S   RE+     L++ +  ++K 
Sbjct: 379 ILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGRERHSCDALNRWLGEQLKQ 438

Query: 545 LMMESGTTMVGYQPQGDKANFFRMVISNPAATQ-SDIDFLIEEIE 588
           L+  SG T++  + +G    F  ++ +    T+  D+D L+  IE
Sbjct: 439 LVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVACIE 483


>gi|31982936 sphingosine-1-phosphate lyase 1 [Homo sapiens]
          Length = 568

 Score = 37.0 bits (84), Expect = 0.051
 Identities = 15/33 (45%), Positives = 22/33 (66%)

Query: 350 YGAFDPIQEIADICEKYNLWLHVDAAWGGGLLM 382
           +G  DP+ E+A +  KY + LHVDA  GG L++
Sbjct: 292 HGVIDPVPEVAKLAVKYKIPLHVDACLGGFLIV 324


>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
          Length = 2325

 Score = 30.4 bits (67), Expect = 4.8
 Identities = 28/107 (26%), Positives = 46/107 (42%), Gaps = 12/107 (11%)

Query: 53  RTNSLEEKSRLVSAFKERQSSKNLL---------SCENSDRDARFRRTETDFSNLFARDL 103
           R   LE+ +      KERQ+ KN L           ENS+  A+ +  + D +NL  + L
Sbjct: 731 RLTQLEQSALQAELEKERQALKNALGKAQFSEEKEQENSELHAKLKHLQDD-NNLLKQQL 789

Query: 104 LPAKNGEEQTVQFLL--EVVDILLNYVRKTFDRSTKVLDFHHPHQLL 148
              +N     V  L+  E V   ++ +R+     T  ++ H P  +L
Sbjct: 790 KDFQNHLNHVVDGLVRPEEVAARVDELRRKLKLGTGEMNIHSPSDVL 836


>gi|68299759 ecotropic viral integration site 5 [Homo sapiens]
          Length = 810

 Score = 29.6 bits (65), Expect = 8.2
 Identities = 21/89 (23%), Positives = 36/89 (40%)

Query: 493 KIKNREEFEMVFNGEPEHTNVCFWYIPQSLRGVPDSPQRREKLHKVAPKIKALMMESGTT 552
           K K ++  E+V  G P H     W +  S + +P   Q  E L   +P  K +  +   T
Sbjct: 150 KKKEKQVKELVHKGIPHHFRAIVWQLLCSAQSMPIKDQYSELLKMTSPCEKLIRRDIART 209

Query: 553 MVGYQPQGDKANFFRMVISNPAATQSDID 581
              +    +K +  + V+ N     S +D
Sbjct: 210 YPEHNFFKEKDSLGQEVLFNVMKAYSLVD 238


>gi|33620755 YEATS domain containing 2 [Homo sapiens]
          Length = 1422

 Score = 29.6 bits (65), Expect = 8.2
 Identities = 27/83 (32%), Positives = 40/83 (48%), Gaps = 10/83 (12%)

Query: 73  SKNLLSCENSDRDARFRRTETDFSNLFARDLLPAKNGEEQTVQFLLEVVDILLNYVRKTF 132
           +K   + ENS RDA  ++ ET     FA   L  KN E +     +EV+D  L   R+  
Sbjct: 24  NKRHKAIENSARDAAVQKIETIIKEQFA---LEMKNKEHE-----IEVIDQRLIEARRMM 75

Query: 133 D--RSTKVLDFHHPHQLLEGMEG 153
           D  R+  V +++    LL+  EG
Sbjct: 76  DKLRACIVANYYASAGLLKVSEG 98


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,983,863
Number of Sequences: 37866
Number of extensions: 962325
Number of successful extensions: 2151
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 2123
Number of HSP's gapped (non-prelim): 16
length of query: 594
length of database: 18,247,518
effective HSP length: 108
effective length of query: 486
effective length of database: 14,157,990
effective search space: 6880783140
effective search space used: 6880783140
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.