Search of human proteins with 5729980

Search of human proteins with 5729980

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5729980 phosphomevalonate kinase [Homo sapiens]
         (192 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5729980 phosphomevalonate kinase [Homo sapiens]                    391   e-109
gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo sapi...    31   0.57 
gi|98991763 eyes absent 4 isoform b [Homo sapiens]                     30   0.97 
gi|98991760 eyes absent 4 isoform a [Homo sapiens]                     30   0.97 
gi|26667257 eyes absent 4 isoform d [Homo sapiens]                     30   1.6  
gi|18104959 thioredoxin domain containing 9 [Homo sapiens]             28   3.7  
gi|15147330 cytochrome P450, family 2, subfamily A, polypeptide ...    28   3.7  
gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens]            28   6.3  
gi|150417973 supervillin isoform 2 [Homo sapiens]                      27   8.2  
gi|150417971 supervillin isoform 1 [Homo sapiens]                      27   8.2  
gi|164419736 glutamate receptor, ionotrophic, AMPA 4 isoform 2 p...    27   8.2  
gi|164419734 glutamate receptor, ionotrophic, AMPA 4 isoform 1 p...    27   8.2  

>gi|5729980 phosphomevalonate kinase [Homo sapiens]
          Length = 192

 Score =  391 bits (1004), Expect = e-109
 Identities = 192/192 (100%), Positives = 192/192 (100%)

Query: 1   MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
           MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ
Sbjct: 1   MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60

Query: 61  RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
           RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE
Sbjct: 61  RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120

Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
           AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ
Sbjct: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180

Query: 181 LENLIEFIRSRL 192
           LENLIEFIRSRL
Sbjct: 181 LENLIEFIRSRL 192


>gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo
           sapiens]
          Length = 703

 Score = 31.2 bits (69), Expect = 0.57
 Identities = 15/51 (29%), Positives = 30/51 (58%), Gaps = 2/51 (3%)

Query: 50  QYAQEHGLNFQRLLDTSTYKEAFRKDMIRWGEEKR--QADPGFFCRKIVEG 98
           ++ QEH LN++ L+  +T +E  +K ++++   ++  + DP    R IV G
Sbjct: 563 KWCQEHFLNYKGLVRAATVREQLKKLLVKFQVPRKSSEGDPDLVLRCIVSG 613


>gi|98991763 eyes absent 4 isoform b [Homo sapiens]
          Length = 616

 Score = 30.4 bits (67), Expect = 0.97
 Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 1/59 (1%)

Query: 4   LGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRL 62
           LGGA  +  ++S   K GK+   E +  R G  V  V+   G  +EQ A++H + F R+
Sbjct: 541 LGGAFPIENIYSAT-KIGKESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHNMPFWRI 598


>gi|98991760 eyes absent 4 isoform a [Homo sapiens]
          Length = 639

 Score = 30.4 bits (67), Expect = 0.97
 Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 1/59 (1%)

Query: 4   LGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRL 62
           LGGA  +  ++S   K GK+   E +  R G  V  V+   G  +EQ A++H + F R+
Sbjct: 564 LGGAFPIENIYSAT-KIGKESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHNMPFWRI 621


>gi|26667257 eyes absent 4 isoform d [Homo sapiens]
          Length = 639

 Score = 29.6 bits (65), Expect = 1.6
 Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 1/59 (1%)

Query: 4   LGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRL 62
           LGGA  +  ++S   K GK+   E + SR G ++  V+   G  +E  A +H + F R+
Sbjct: 564 LGGAFPIENIYSAT-KIGKESCFERIVSRFGTNITYVVIGDGRDEEHAANQHNMPFWRI 621


>gi|18104959 thioredoxin domain containing 9 [Homo sapiens]
          Length = 226

 Score = 28.5 bits (62), Expect = 3.7
 Identities = 24/68 (35%), Positives = 32/68 (47%), Gaps = 15/68 (22%)

Query: 8   PRLVLLFSGKRK----------SGKDFVTEALQSRLGADVCAVLRLSGPLKE---QYAQE 54
           P L LL  GK +          +  DF TE L+ RLG+    +L  SG L E   Q  ++
Sbjct: 144 PTLALLKDGKTQDYVVGFTDLGNTDDFTTETLEWRLGSS--DILNYSGNLMEPPFQNQKK 201

Query: 55  HGLNFQRL 62
            G NF +L
Sbjct: 202 FGTNFTKL 209


>gi|15147330 cytochrome P450, family 2, subfamily A, polypeptide 7
           isoform 1 [Homo sapiens]
          Length = 494

 Score = 28.5 bits (62), Expect = 3.7
 Identities = 14/39 (35%), Positives = 19/39 (48%)

Query: 149 VDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLIEF 187
           VD AE   G      FDWV + +GV     E+ + L+ F
Sbjct: 92  VDQAEEFSGRGEQATFDWVFKGYGVAFSNGERAKQLLRF 130


>gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens]
          Length = 4523

 Score = 27.7 bits (60), Expect = 6.3
 Identities = 30/117 (25%), Positives = 49/117 (41%), Gaps = 15/117 (12%)

Query: 40   VLRLSGPLKEQYAQEHGLNFQRLLDTSTYKEAFRKDMIRWGEEKRQADPGFF-------C 92
            +LR   P +  YA     NF      + Y E  R D+++  EE   A P FF        
Sbjct: 3890 LLRAMRPDRMTYALR---NFVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPGVDA 3946

Query: 93   RKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVTQTVRVVALEQSRQQRGWVFTPGV 149
             K +E + + +    D+ +  ++     + G   +TV  VALE++ +   WV    V
Sbjct: 3947 LKDLEILGKRLGFTIDSGKFHNV-----SLGQGQETVAEVALEKASKGGHWVILQNV 3998


>gi|150417973 supervillin isoform 2 [Homo sapiens]
          Length = 2214

 Score = 27.3 bits (59), Expect = 8.2
 Identities = 26/99 (26%), Positives = 42/99 (42%), Gaps = 7/99 (7%)

Query: 63  LDTSTYKEAFRKDMIRWGEE-KRQADPGFFCRKIVEGI------SQPIWLVSDTRRVSDI 115
           L  S +++A  KD    G+E   Q +P      + E +      SQP+     TR   D 
Sbjct: 782 LQASAHQKALAKDQTNEGKELAEQGEPDSSTLSLAEKLALFNKLSQPVSKAISTRNRIDT 841

Query: 116 QWFREAYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAES 154
           +  R      TQ V +  +EQ +  +   F+P V+ + S
Sbjct: 842 RQRRMNARYQTQPVTLGEVEQVQSGKLIPFSPAVNTSVS 880


>gi|150417971 supervillin isoform 1 [Homo sapiens]
          Length = 1788

 Score = 27.3 bits (59), Expect = 8.2
 Identities = 26/99 (26%), Positives = 42/99 (42%), Gaps = 7/99 (7%)

Query: 63  LDTSTYKEAFRKDMIRWGEE-KRQADPGFFCRKIVEGI------SQPIWLVSDTRRVSDI 115
           L  S +++A  KD    G+E   Q +P      + E +      SQP+     TR   D 
Sbjct: 356 LQASAHQKALAKDQTNEGKELAEQGEPDSSTLSLAEKLALFNKLSQPVSKAISTRNRIDT 415

Query: 116 QWFREAYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAES 154
           +  R      TQ V +  +EQ +  +   F+P V+ + S
Sbjct: 416 RQRRMNARYQTQPVTLGEVEQVQSGKLIPFSPAVNTSVS 454


>gi|164419736 glutamate receptor, ionotrophic, AMPA 4 isoform 2
           precursor [Homo sapiens]
          Length = 884

 Score = 27.3 bits (59), Expect = 8.2
 Identities = 25/87 (28%), Positives = 43/87 (49%), Gaps = 10/87 (11%)

Query: 24  FVTEALQSRLGADVCAVL---RLSGPLK--EQYAQEHGLNFQRLLDTSTYKEAFRKDMIR 78
           F T  + S   A++ A L   R+  P++  E  A++  + +  L D+ + KE FR+  I 
Sbjct: 629 FFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTL-DSGSTKEFFRRSKIA 687

Query: 79  WGEEK----RQADPGFFCRKIVEGISQ 101
             E+     R A+P  F R   EG+++
Sbjct: 688 VYEKMWTYMRSAEPSVFTRTTAEGVAR 714


>gi|164419734 glutamate receptor, ionotrophic, AMPA 4 isoform 1
           precursor [Homo sapiens]
          Length = 902

 Score = 27.3 bits (59), Expect = 8.2
 Identities = 25/87 (28%), Positives = 43/87 (49%), Gaps = 10/87 (11%)

Query: 24  FVTEALQSRLGADVCAVL---RLSGPLK--EQYAQEHGLNFQRLLDTSTYKEAFRKDMIR 78
           F T  + S   A++ A L   R+  P++  E  A++  + +  L D+ + KE FR+  I 
Sbjct: 629 FFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTL-DSGSTKEFFRRSKIA 687

Query: 79  WGEEK----RQADPGFFCRKIVEGISQ 101
             E+     R A+P  F R   EG+++
Sbjct: 688 VYEKMWTYMRSAEPSVFTRTTAEGVAR 714


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.138    0.420 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,228,108
Number of Sequences: 37866
Number of extensions: 289618
Number of successful extensions: 563
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 558
Number of HSP's gapped (non-prelim): 13
length of query: 192
length of database: 18,247,518
effective HSP length: 97
effective length of query: 95
effective length of database: 14,574,516
effective search space: 1384579020
effective search space used: 1384579020
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.