Guide to the Human Genome
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Search of human proteins with 55956775

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|55956775 sterol carrier protein 2 isoform 2 [Homo sapiens]
         (322 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|55956775 sterol carrier protein 2 isoform 2 [Homo sapiens]         657   0.0  
gi|19923233 sterol carrier protein 2 isoform 1 proprotein [Homo ...   626   e-180
gi|4501853 acetyl-Coenzyme A acyltransferase 1 isoform a [Homo s...    52   9e-07
gi|4504327 mitochondrial trifunctional protein, beta subunit pre...    45   7e-05
gi|148539872 acetyl-Coenzyme A acetyltransferase 2 [Homo sapiens]      45   9e-05
gi|194353979 acetyl-Coenzyme A acyltransferase 1 isoform b [Homo...    44   1e-04
gi|167614485 acetyl-coenzyme A acyltransferase 2 [Homo sapiens]        37   0.024
gi|4557237 acetyl-Coenzyme A acetyltransferase 1 precursor [Homo...    31   1.7  
gi|229892270 WD repeats and SOF1 domain containing [Homo sapiens]      30   2.9  
gi|4505817 phosphatidylinositol-4-phosphate 5-kinase, type I, be...    29   4.9  
gi|4503503 eukaryotic translation initiation factor 2B, subunit ...    29   4.9  

>gi|55956775 sterol carrier protein 2 isoform 2 [Homo sapiens]
          Length = 322

 Score =  657 bits (1696), Expect = 0.0
 Identities = 322/322 (100%), Positives = 322/322 (100%)

Query: 1   MSSSPWEPATLRRVFVVGVGMTKFVKPGAENSRDYPDLAEEAGKKALADAQIPYSAVDQA 60
           MSSSPWEPATLRRVFVVGVGMTKFVKPGAENSRDYPDLAEEAGKKALADAQIPYSAVDQA
Sbjct: 1   MSSSPWEPATLRRVFVVGVGMTKFVKPGAENSRDYPDLAEEAGKKALADAQIPYSAVDQA 60

Query: 61  CVGYVFGVAECVLALGFEKMSKGSLGIKFSDRTIPTDKHVDLLINKYGLSAHPVAPQMFG 120
           CVGYVFGVAECVLALGFEKMSKGSLGIKFSDRTIPTDKHVDLLINKYGLSAHPVAPQMFG
Sbjct: 61  CVGYVFGVAECVLALGFEKMSKGSLGIKFSDRTIPTDKHVDLLINKYGLSAHPVAPQMFG 120

Query: 121 YAGKEHMEKYGTKIEHFAKIGWKNHKHSVNNPYSQFQDEYSLDEVMASKEVFDFLTILQC 180
           YAGKEHMEKYGTKIEHFAKIGWKNHKHSVNNPYSQFQDEYSLDEVMASKEVFDFLTILQC
Sbjct: 121 YAGKEHMEKYGTKIEHFAKIGWKNHKHSVNNPYSQFQDEYSLDEVMASKEVFDFLTILQC 180

Query: 181 CPTSDGAAAAILASEAFVQKYGLQSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDMSKEA 240
           CPTSDGAAAAILASEAFVQKYGLQSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDMSKEA
Sbjct: 181 CPTSDGAAAAILASEAFVQKYGLQSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDMSKEA 240

Query: 241 ARKCYEKSGLTPNDIDVIELHDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWVI 300
           ARKCYEKSGLTPNDIDVIELHDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWVI
Sbjct: 241 ARKCYEKSGLTPNDIDVIELHDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWVI 300

Query: 301 NPSGGLISKGHPLGATGGHSCS 322
           NPSGGLISKGHPLGATGGHSCS
Sbjct: 301 NPSGGLISKGHPLGATGGHSCS 322


>gi|19923233 sterol carrier protein 2 isoform 1 proprotein [Homo
           sapiens]
          Length = 547

 Score =  626 bits (1614), Expect = e-180
 Identities = 318/366 (86%), Positives = 319/366 (87%), Gaps = 44/366 (12%)

Query: 1   MSSSPWEPATLRRVFVVGVGMTKFVKPGAENSRDYPDLAEEAGKKALADAQIPYSAVDQA 60
           MSSSPWEPATLRRVFVVGVGMTKFVKPGAENSRDYPDLAEEAGKKALADAQIPYSAVDQA
Sbjct: 1   MSSSPWEPATLRRVFVVGVGMTKFVKPGAENSRDYPDLAEEAGKKALADAQIPYSAVDQA 60

Query: 61  CVGYVFG--------------------------------------------VAECVLALG 76
           CVGYVFG                                            VAECVLALG
Sbjct: 61  CVGYVFGDSTCGQRAIYHSLGMTGIPIINVNNNCATGSTALFMARQLIQGGVAECVLALG 120

Query: 77  FEKMSKGSLGIKFSDRTIPTDKHVDLLINKYGLSAHPVAPQMFGYAGKEHMEKYGTKIEH 136
           FEKMSKGSLGIKFSDRTIPTDKHVDLLINKYGLSAHPVAPQMFGYAGKEHMEKYGTKIEH
Sbjct: 121 FEKMSKGSLGIKFSDRTIPTDKHVDLLINKYGLSAHPVAPQMFGYAGKEHMEKYGTKIEH 180

Query: 137 FAKIGWKNHKHSVNNPYSQFQDEYSLDEVMASKEVFDFLTILQCCPTSDGAAAAILASEA 196
           FAKIGWKNHKHSVNNPYSQFQDEYSLDEVMASKEVFDFLTILQCCPTSDGAAAAILASEA
Sbjct: 181 FAKIGWKNHKHSVNNPYSQFQDEYSLDEVMASKEVFDFLTILQCCPTSDGAAAAILASEA 240

Query: 197 FVQKYGLQSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARKCYEKSGLTPNDID 256
           FVQKYGLQSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARKCYEKSGLTPNDID
Sbjct: 241 FVQKYGLQSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARKCYEKSGLTPNDID 300

Query: 257 VIELHDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWVINPSGGLISKGHPLGAT 316
           VIELHDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWVINPSGGLISKGHPLGAT
Sbjct: 301 VIELHDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWVINPSGGLISKGHPLGAT 360

Query: 317 GGHSCS 322
           G   C+
Sbjct: 361 GLAQCA 366


>gi|4501853 acetyl-Coenzyme A acyltransferase 1 isoform a [Homo
           sapiens]
          Length = 424

 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 39/134 (29%), Positives = 61/134 (45%), Gaps = 29/134 (21%)

Query: 184 SDGAAAAILASEAFVQKYGLQSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARK 243
           SDGAAA +LA  +  ++ GL    + +L    +  +P        I  +G      A   
Sbjct: 279 SDGAAAILLARRSKAEELGLP--ILGVLRSYAVVGVPPD------IMGIG---PAYAIPV 327

Query: 244 CYEKSGLTPNDIDVIELHDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWVINPS 303
             +K+GLT +D+D+ E+++ F++      E L L PE                   +NP 
Sbjct: 328 ALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPE------------------KVNPL 369

Query: 304 GGLISKGHPLGATG 317
           GG ++ GHPLG TG
Sbjct: 370 GGAVALGHPLGCTG 383


>gi|4504327 mitochondrial trifunctional protein, beta subunit
           precursor [Homo sapiens]
          Length = 474

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 41/143 (28%), Positives = 59/143 (41%), Gaps = 29/143 (20%)

Query: 184 SDGAAAAILASEAFVQKYGLQSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARK 243
           +DGA+A ++ +E      G + KA        + D     ++     ++G      A  K
Sbjct: 312 TDGASAMLIMAEEKALAMGYKPKAY-------LRDFMYVSQDPKDQLLLG---PTYATPK 361

Query: 244 CYEKSGLTPNDIDVIELHDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWV---- 299
             EK+GLT NDID  E H+ FS   L  ++A+            D     Y G+      
Sbjct: 362 VLEKAGLTMNDIDAFEFHEAFSGQILANFKAMD----------SDWFAENYMGRKTKVGL 411

Query: 300 -----INPSGGLISKGHPLGATG 317
                 N  GG +S GHP GATG
Sbjct: 412 PPLEKFNNWGGSLSLGHPFGATG 434


>gi|148539872 acetyl-Coenzyme A acetyltransferase 2 [Homo sapiens]
          Length = 397

 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 37/134 (27%), Positives = 59/134 (44%), Gaps = 29/134 (21%)

Query: 184 SDGAAAAILASEAFVQKYGLQSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARK 243
           +DGAAA +L  ++   K GL   A  +   ++         E SI+ +      K+A  K
Sbjct: 255 NDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGV-------EPSIMGIGPIPAIKQAVTK 307

Query: 244 CYEKSGLTPNDIDVIELHDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWVINPS 303
               +G +  D+D+ E+++ F+       + LGL PE                   +N  
Sbjct: 308 ----AGWSLEDVDIFEINEAFAAVSAAIVKELGLNPE------------------KVNIE 345

Query: 304 GGLISKGHPLGATG 317
           GG I+ GHPLGA+G
Sbjct: 346 GGAIALGHPLGASG 359


>gi|194353979 acetyl-Coenzyme A acyltransferase 1 isoform b [Homo
           sapiens]
          Length = 331

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 23/70 (32%), Positives = 35/70 (50%), Gaps = 18/70 (25%)

Query: 248 SGLTPNDIDVIELHDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWVINPSGGLI 307
           +GLT +D+D+ E+++ F++      E L L PE                   +NP GG +
Sbjct: 239 AGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEK------------------VNPLGGAV 280

Query: 308 SKGHPLGATG 317
           + GHPLG TG
Sbjct: 281 ALGHPLGCTG 290


>gi|167614485 acetyl-coenzyme A acyltransferase 2 [Homo sapiens]
          Length = 397

 Score = 37.0 bits (84), Expect = 0.024
 Identities = 35/134 (26%), Positives = 57/134 (42%), Gaps = 29/134 (21%)

Query: 184 SDGAAAAILASEAFVQKYGLQSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARK 243
           +DGA A I+ASE  V+K+     A  I+   +    PS      +  + G          
Sbjct: 254 ADGAGAVIIASEDAVKKHNFTPLA-RIVGYFVSGCDPSIMGIGPVPAISG---------- 302

Query: 244 CYEKSGLTPNDIDVIELHDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWVINPS 303
             +K+GL+  D+D++E+++ F+   L    +L L                       N +
Sbjct: 303 ALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKT------------------NVN 344

Query: 304 GGLISKGHPLGATG 317
           GG I+ GHPLG +G
Sbjct: 345 GGAIALGHPLGGSG 358


>gi|4557237 acetyl-Coenzyme A acetyltransferase 1 precursor [Homo
           sapiens]
          Length = 427

 Score = 30.8 bits (68), Expect = 1.7
 Identities = 21/78 (26%), Positives = 34/78 (43%), Gaps = 18/78 (23%)

Query: 240 AARKCYEKSGLTPNDIDVIELHDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWV 299
           AA    +  GL   DI + E+++ FS   L   + L + P+                   
Sbjct: 332 AASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQK------------------ 373

Query: 300 INPSGGLISKGHPLGATG 317
           +N +GG +S GHP+G +G
Sbjct: 374 VNINGGAVSLGHPIGMSG 391


>gi|229892270 WD repeats and SOF1 domain containing [Homo sapiens]
          Length = 597

 Score = 30.0 bits (66), Expect = 2.9
 Identities = 16/51 (31%), Positives = 26/51 (50%), Gaps = 1/51 (1%)

Query: 122 AGKEHMEKYGTKIEHFAKIGW-KNHKHSVNNPYSQFQDEYSLDEVMASKEV 171
           A K++ +K   K +H+  I     H+H   + YSQ Q++  + E    KEV
Sbjct: 521 AAKDYNQKLKEKFQHYPHIKRIARHRHLPKSIYSQIQEQRIMKEARRRKEV 571


>gi|4505817 phosphatidylinositol-4-phosphate 5-kinase, type I, beta
           isoform 2 [Homo sapiens]
          Length = 540

 Score = 29.3 bits (64), Expect = 4.9
 Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 6/82 (7%)

Query: 197 FVQKYGLQSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARKCYEKSGLTPNDID 256
           F   Y +QS  + I    M   LP S        + G    + A+RK  EKS  T  D+D
Sbjct: 170 FYGLYCMQSGGINIRIVVMNNVLPRSMRMHFTYDLKGSTYKRRASRKEREKSNPTFKDLD 229

Query: 257 VI-ELHD--CFSTNELLTYEAL 275
            + ++H+   F T    TY AL
Sbjct: 230 FLQDMHEGLYFDTE---TYNAL 248


>gi|4503503 eukaryotic translation initiation factor 2B, subunit 1
           alpha, 26kDa [Homo sapiens]
          Length = 305

 Score = 29.3 bits (64), Expect = 4.9
 Identities = 14/38 (36%), Positives = 21/38 (55%)

Query: 36  PDLAEEAGKKALADAQIPYSAVDQACVGYVFGVAECVL 73
           PDL+ +   KAL    +P + V  A VGY+   A+ V+
Sbjct: 157 PDLSGKKMAKALCHLNVPVTVVLDAAVGYIMEKADLVI 194


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.134    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,179,976
Number of Sequences: 37866
Number of extensions: 523377
Number of successful extensions: 1046
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1028
Number of HSP's gapped (non-prelim): 13
length of query: 322
length of database: 18,247,518
effective HSP length: 102
effective length of query: 220
effective length of database: 14,385,186
effective search space: 3164740920
effective search space used: 3164740920
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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