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Search of human proteins with 55953063
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55953063 SET domain containing 4 isoform c [Homo sapiens]
(307 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55953063 SET domain containing 4 isoform c [Homo sapiens] 639 0.0
gi|8393013 SET domain containing 4 isoform a [Homo sapiens] 622 e-178
gi|40068481 SET domain containing 3 isoform a [Homo sapiens] 67 3e-11
gi|40068483 SET domain containing 3 isoform b [Homo sapiens] 48 1e-05
gi|238550107 SET domain containing 6 isoform a [Homo sapiens] 46 5e-05
gi|238550105 SET domain containing 6 isoform b [Homo sapiens] 46 5e-05
gi|156616308 SET and MYND domain containing 4 [Homo sapiens] 36 0.037
gi|239753559 PREDICTED: hypothetical protein XP_002345696 [Homo ... 31 1.6
gi|239748103 PREDICTED: hypothetical protein [Homo sapiens] 31 1.6
gi|239741999 PREDICTED: hypothetical protein XP_002342370 [Homo ... 31 1.6
gi|217272890 palmitoyl-protein thioesterase 1 isoform 2 precurso... 29 4.6
gi|4506031 palmitoyl-protein thioesterase 1 isoform 1 precursor ... 29 4.6
gi|157785656 nudix motif 7 [Homo sapiens] 29 4.6
gi|4758222 dual-specificity tyrosine-(Y)-phosphorylation regulat... 28 7.8
gi|5922001 dual-specificity tyrosine-(Y)-phosphorylation regulat... 28 7.8
gi|5921999 dual-specificity tyrosine-(Y)-phosphorylation regulat... 28 7.8
gi|144953913 zinc finger protein 714 [Homo sapiens] 28 7.8
>gi|55953063 SET domain containing 4 isoform c [Homo sapiens]
Length = 307
Score = 639 bits (1648), Expect = 0.0
Identities = 307/307 (100%), Positives = 307/307 (100%)
Query: 1 MQKGKGRTSRIRRRKLCGSSESRGVNESHKSEFIELRKWLKARKFQDSNLAPACFPGTGR 60
MQKGKGRTSRIRRRKLCGSSESRGVNESHKSEFIELRKWLKARKFQDSNLAPACFPGTGR
Sbjct: 1 MQKGKGRTSRIRRRKLCGSSESRGVNESHKSEFIELRKWLKARKFQDSNLAPACFPGTGR 60
Query: 61 GLMSQTSLQEGQMIISLPESCLLTTDTVIRSYLGAYITKWKPPPSPLLALCTFLVSEKHA 120
GLMSQTSLQEGQMIISLPESCLLTTDTVIRSYLGAYITKWKPPPSPLLALCTFLVSEKHA
Sbjct: 61 GLMSQTSLQEGQMIISLPESCLLTTDTVIRSYLGAYITKWKPPPSPLLALCTFLVSEKHA 120
Query: 121 GHRSLWKPYLEILPKAYTCPVCLEPEVVNLLPKSLKAKAEEQRAHVQEFFASSRDFFSSL 180
GHRSLWKPYLEILPKAYTCPVCLEPEVVNLLPKSLKAKAEEQRAHVQEFFASSRDFFSSL
Sbjct: 121 GHRSLWKPYLEILPKAYTCPVCLEPEVVNLLPKSLKAKAEEQRAHVQEFFASSRDFFSSL 180
Query: 181 QPLFAEAVDSIFSYSALLWAWCTVNTRAVYLRPRQRECLSAEPDTCALAPYLDLLNHSPH 240
QPLFAEAVDSIFSYSALLWAWCTVNTRAVYLRPRQRECLSAEPDTCALAPYLDLLNHSPH
Sbjct: 181 QPLFAEAVDSIFSYSALLWAWCTVNTRAVYLRPRQRECLSAEPDTCALAPYLDLLNHSPH 240
Query: 241 VQVKAAFNEETHSYEIRTTSRWRKHEEVFICYGPHDNQRLFLEYGFVSVHNPHACVYVSR 300
VQVKAAFNEETHSYEIRTTSRWRKHEEVFICYGPHDNQRLFLEYGFVSVHNPHACVYVSR
Sbjct: 241 VQVKAAFNEETHSYEIRTTSRWRKHEEVFICYGPHDNQRLFLEYGFVSVHNPHACVYVSR 300
Query: 301 GWNQLCS 307
GWNQLCS
Sbjct: 301 GWNQLCS 307
>gi|8393013 SET domain containing 4 isoform a [Homo sapiens]
Length = 440
Score = 622 bits (1603), Expect = e-178
Identities = 300/300 (100%), Positives = 300/300 (100%)
Query: 1 MQKGKGRTSRIRRRKLCGSSESRGVNESHKSEFIELRKWLKARKFQDSNLAPACFPGTGR 60
MQKGKGRTSRIRRRKLCGSSESRGVNESHKSEFIELRKWLKARKFQDSNLAPACFPGTGR
Sbjct: 1 MQKGKGRTSRIRRRKLCGSSESRGVNESHKSEFIELRKWLKARKFQDSNLAPACFPGTGR 60
Query: 61 GLMSQTSLQEGQMIISLPESCLLTTDTVIRSYLGAYITKWKPPPSPLLALCTFLVSEKHA 120
GLMSQTSLQEGQMIISLPESCLLTTDTVIRSYLGAYITKWKPPPSPLLALCTFLVSEKHA
Sbjct: 61 GLMSQTSLQEGQMIISLPESCLLTTDTVIRSYLGAYITKWKPPPSPLLALCTFLVSEKHA 120
Query: 121 GHRSLWKPYLEILPKAYTCPVCLEPEVVNLLPKSLKAKAEEQRAHVQEFFASSRDFFSSL 180
GHRSLWKPYLEILPKAYTCPVCLEPEVVNLLPKSLKAKAEEQRAHVQEFFASSRDFFSSL
Sbjct: 121 GHRSLWKPYLEILPKAYTCPVCLEPEVVNLLPKSLKAKAEEQRAHVQEFFASSRDFFSSL 180
Query: 181 QPLFAEAVDSIFSYSALLWAWCTVNTRAVYLRPRQRECLSAEPDTCALAPYLDLLNHSPH 240
QPLFAEAVDSIFSYSALLWAWCTVNTRAVYLRPRQRECLSAEPDTCALAPYLDLLNHSPH
Sbjct: 181 QPLFAEAVDSIFSYSALLWAWCTVNTRAVYLRPRQRECLSAEPDTCALAPYLDLLNHSPH 240
Query: 241 VQVKAAFNEETHSYEIRTTSRWRKHEEVFICYGPHDNQRLFLEYGFVSVHNPHACVYVSR 300
VQVKAAFNEETHSYEIRTTSRWRKHEEVFICYGPHDNQRLFLEYGFVSVHNPHACVYVSR
Sbjct: 241 VQVKAAFNEETHSYEIRTTSRWRKHEEVFICYGPHDNQRLFLEYGFVSVHNPHACVYVSR 300
>gi|40068481 SET domain containing 3 isoform a [Homo sapiens]
Length = 594
Score = 66.6 bits (161), Expect = 3e-11
Identities = 69/295 (23%), Positives = 118/295 (40%), Gaps = 14/295 (4%)
Query: 10 RIRRRKLCGSSESRGVNESHKSEFIELRKWLKARKFQDSNLAPACFPGTGRGLMSQTSLQ 69
+IR+++ S G E + F +L KW F G GL + ++
Sbjct: 59 KIRKKQKGLSVTFDGKREDY---FPDLMKWASENGASVEGFEMVNFKEEGFGLRATRDIK 115
Query: 70 EGQMIISLPESCLLTTDTVIRSYLGAYITKWKPPPSP-LLALCTFLVSEKHAGHRSLWKP 128
++ + +P L+T ++ S LG ++ + + +AL L+ E+ A S W+P
Sbjct: 116 AEELFLWVPRKLLMTVESAKNSVLGPLYSQDRILQAMGNIALAFHLLCER-ASPNSFWQP 174
Query: 129 YLEILPKAYTCPVCLEPEVVNLLPKSLKAKAE--EQRAHVQEFFASSRDFFSSLQPLFAE 186
Y++ LP Y P+ E + V L +S +A + Q + +A +
Sbjct: 175 YIQTLPSEYDTPLYFEEDEVRYL-QSTQAIHDVFSQYKNTARQYAYFYKVIQTHPHANKL 233
Query: 187 AVDSIFSYSALLWAWCTVNTRAVYLRPRQRECLSAEPDTCALAPYLDLLNHSPHVQVKAA 246
+ F+Y WA +V T R Q T AL P D+ NH+ + +
Sbjct: 234 PLKDSFTYEDYRWAVSSVMT-----RQNQIPTEDGSRVTLALIPLWDMCNHTNGL-ITTG 287
Query: 247 FNEETHSYEIRTTSRWRKHEEVFICYGPHDNQRLFLEYGFVSVHNPHACVYVSRG 301
+N E E +R E+++I YG N + GF +N H V + G
Sbjct: 288 YNLEDDRCECVALQDFRAGEQIYIFYGTRSNAEFVIHSGFFFDNNSHDRVKIKLG 342
>gi|40068483 SET domain containing 3 isoform b [Homo sapiens]
Length = 296
Score = 47.8 bits (112), Expect = 1e-05
Identities = 54/232 (23%), Positives = 93/232 (40%), Gaps = 13/232 (5%)
Query: 10 RIRRRKLCGSSESRGVNESHKSEFIELRKWLKARKFQDSNLAPACFPGTGRGLMSQTSLQ 69
+IR+++ S G E + F +L KW F G GL + ++
Sbjct: 59 KIRKKQKGLSVTFDGKREDY---FPDLMKWASENGASVEGFEMVNFKEEGFGLRATRDIK 115
Query: 70 EGQMIISLPESCLLTTDTVIRSYLGAYITKWKPPPSP-LLALCTFLVSEKHAGHRSLWKP 128
++ + +P L+T ++ S LG ++ + + +AL L+ E+ A S W+P
Sbjct: 116 AEELFLWVPRKLLMTVESAKNSVLGPLYSQDRILQAMGNIALAFHLLCER-ASPNSFWQP 174
Query: 129 YLEILPKAYTCPVCLEPEVVNLLPKSLKAKAE--EQRAHVQEFFASSRDFFSSLQPLFAE 186
Y++ LP Y P+ E + V L +S +A + Q + +A +
Sbjct: 175 YIQTLPSEYDTPLYFEEDEVRYL-QSTQAIHDVFSQYKNTARQYAYFYKVIQTHPHANKL 233
Query: 187 AVDSIFSYSALLWAWCTVNTRAVYLRPRQRECLSAEPDTCALAPYLDLLNHS 238
+ F+Y WA +V T R Q T AL P D+ NH+
Sbjct: 234 PLKDSFTYEDYRWAVSSVMT-----RQNQIPTEDGSRVTLALIPLWDMCNHT 280
>gi|238550107 SET domain containing 6 isoform a [Homo sapiens]
Length = 473
Score = 45.8 bits (107), Expect = 5e-05
Identities = 58/248 (23%), Positives = 101/248 (40%), Gaps = 40/248 (16%)
Query: 59 GRGLMSQTSLQEGQMIISLPESCLLTTDTVIRSYLGAYITKWK---PPPSPLLALCTFLV 115
G G++++ S+Q G+++ +P + LL+ T +G + + + S + L L+
Sbjct: 74 GYGMVARESVQAGELLFVVPRAALLSQHTCS---IGGLLERERVALQSQSGWVPLLLALL 130
Query: 116 SEKHAGHRSLWKPYLEILPKAYTC--PVCLEPE----------VVNLLPKSLKAKAEEQR 163
E A S W+PY + P+ P+ E V + K L E +
Sbjct: 131 HELQAP-ASRWRPYFALWPELGRLEHPMFWPEEERRCLLQGTGVPEAVEKDLANIRSEYQ 189
Query: 164 AHVQEFFASSRDFFS----SLQPLFAEAVDSIFSYSALLWAWCTVNTRAVYLRPRQRECL 219
+ V F + D FS SL+ L+ + V + +YS + P + E
Sbjct: 190 SIVLPFMEAHPDLFSLRVRSLE-LYHQLVALVMAYS--------------FQEPLEEEED 234
Query: 220 SAEPDTCALAPYLDLLNHSPHVQVKAAFNEETHSYEIRTTSRWRKHEEVFICYGPHDNQR 279
EP++ + P D+LNH + ++ + + T K E+F YG N +
Sbjct: 235 EKEPNSPVMVPAADILNHLANHNANLEYS--ANCLRMVATQPIPKGHEIFNTYGQMANWQ 292
Query: 280 LFLEYGFV 287
L YGFV
Sbjct: 293 LIHMYGFV 300
>gi|238550105 SET domain containing 6 isoform b [Homo sapiens]
Length = 449
Score = 45.8 bits (107), Expect = 5e-05
Identities = 58/248 (23%), Positives = 101/248 (40%), Gaps = 40/248 (16%)
Query: 59 GRGLMSQTSLQEGQMIISLPESCLLTTDTVIRSYLGAYITKWK---PPPSPLLALCTFLV 115
G G++++ S+Q G+++ +P + LL+ T +G + + + S + L L+
Sbjct: 50 GYGMVARESVQAGELLFVVPRAALLSQHTCS---IGGLLERERVALQSQSGWVPLLLALL 106
Query: 116 SEKHAGHRSLWKPYLEILPKAYTC--PVCLEPE----------VVNLLPKSLKAKAEEQR 163
E A S W+PY + P+ P+ E V + K L E +
Sbjct: 107 HELQAP-ASRWRPYFALWPELGRLEHPMFWPEEERRCLLQGTGVPEAVEKDLANIRSEYQ 165
Query: 164 AHVQEFFASSRDFFS----SLQPLFAEAVDSIFSYSALLWAWCTVNTRAVYLRPRQRECL 219
+ V F + D FS SL+ L+ + V + +YS + P + E
Sbjct: 166 SIVLPFMEAHPDLFSLRVRSLE-LYHQLVALVMAYS--------------FQEPLEEEED 210
Query: 220 SAEPDTCALAPYLDLLNHSPHVQVKAAFNEETHSYEIRTTSRWRKHEEVFICYGPHDNQR 279
EP++ + P D+LNH + ++ + + T K E+F YG N +
Sbjct: 211 EKEPNSPVMVPAADILNHLANHNANLEYS--ANCLRMVATQPIPKGHEIFNTYGQMANWQ 268
Query: 280 LFLEYGFV 287
L YGFV
Sbjct: 269 LIHMYGFV 276
>gi|156616308 SET and MYND domain containing 4 [Homo sapiens]
Length = 804
Score = 36.2 bits (82), Expect = 0.037
Identities = 18/49 (36%), Positives = 26/49 (53%), Gaps = 2/49 (4%)
Query: 230 PYLDLLNHSPHVQVKAAFNEETHSYEIRTTSRWRKHEEVFICYGPHDNQ 278
P + LLNHS +F + IR + R RK +E+ CYGPH ++
Sbjct: 533 PVISLLNHSCSPNTSVSFISTVAT--IRASQRIRKGQEILHCYGPHKSR 579
>gi|239753559 PREDICTED: hypothetical protein XP_002345696 [Homo
sapiens]
Length = 366
Score = 30.8 bits (68), Expect = 1.6
Identities = 19/69 (27%), Positives = 29/69 (42%), Gaps = 8/69 (11%)
Query: 103 PPSPLLALCTFLVSEKHAGHRSLWKPYLEILPKAYTCPVCLEPEVVNLLPKSLKAKAEEQ 162
P SP+ A V + H G + + + CP CLEP + LP+ ++
Sbjct: 126 PASPVTAFAANYVDKVHVGEHCVAIHHTQAPSGPQDCPQCLEPSISWRLPRLVR------ 179
Query: 163 RAHVQEFFA 171
H+QE A
Sbjct: 180 --HLQEVCA 186
>gi|239748103 PREDICTED: hypothetical protein [Homo sapiens]
Length = 366
Score = 30.8 bits (68), Expect = 1.6
Identities = 19/69 (27%), Positives = 29/69 (42%), Gaps = 8/69 (11%)
Query: 103 PPSPLLALCTFLVSEKHAGHRSLWKPYLEILPKAYTCPVCLEPEVVNLLPKSLKAKAEEQ 162
P SP+ A V + H G + + + CP CLEP + LP+ ++
Sbjct: 126 PASPVTAFAANYVDKVHVGEHCVAIHHTQAPSGPQDCPQCLEPSISWRLPRLVR------ 179
Query: 163 RAHVQEFFA 171
H+QE A
Sbjct: 180 --HLQEVCA 186
>gi|239741999 PREDICTED: hypothetical protein XP_002342370 [Homo
sapiens]
Length = 366
Score = 30.8 bits (68), Expect = 1.6
Identities = 19/69 (27%), Positives = 29/69 (42%), Gaps = 8/69 (11%)
Query: 103 PPSPLLALCTFLVSEKHAGHRSLWKPYLEILPKAYTCPVCLEPEVVNLLPKSLKAKAEEQ 162
P SP+ A V + H G + + + CP CLEP + LP+ ++
Sbjct: 126 PASPVTAFAANYVDKVHVGEHCVAIHHTQAPSGPQDCPQCLEPSISWRLPRLVR------ 179
Query: 163 RAHVQEFFA 171
H+QE A
Sbjct: 180 --HLQEVCA 186
>gi|217272890 palmitoyl-protein thioesterase 1 isoform 2 precursor
[Homo sapiens]
Length = 203
Score = 29.3 bits (64), Expect = 4.6
Identities = 12/37 (32%), Positives = 22/37 (59%)
Query: 16 LCGSSESRGVNESHKSEFIELRKWLKARKFQDSNLAP 52
L ++ RG+NES+K + L+K++ + DS + P
Sbjct: 99 LADINQERGINESYKKNLMALKKFVMVKFLNDSIVDP 135
>gi|4506031 palmitoyl-protein thioesterase 1 isoform 1 precursor
[Homo sapiens]
Length = 306
Score = 29.3 bits (64), Expect = 4.6
Identities = 12/37 (32%), Positives = 22/37 (59%)
Query: 16 LCGSSESRGVNESHKSEFIELRKWLKARKFQDSNLAP 52
L ++ RG+NES+K + L+K++ + DS + P
Sbjct: 202 LADINQERGINESYKKNLMALKKFVMVKFLNDSIVDP 238
>gi|157785656 nudix motif 7 [Homo sapiens]
Length = 238
Score = 29.3 bits (64), Expect = 4.6
Identities = 25/90 (27%), Positives = 37/90 (41%), Gaps = 21/90 (23%)
Query: 54 CFPGTGRGLMSQ----TSLQEGQMIISLPES----------CLLTTDTVIRSYLGAYITK 99
CFPG R T+L+E Q + L CL+ TDT+I ++G
Sbjct: 72 CFPGGKRDPTDMDDAATALREAQEEVGLRPHQVEVVCCLVPCLIDTDTLITPFVGLIDHN 131
Query: 100 WKPPPSP-------LLALCTFLVSEKHAGH 122
++ P+P L+ L FL + H H
Sbjct: 132 FQAQPNPAEVKDVFLVPLAYFLHPQVHDQH 161
>gi|4758222 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1B isoform a [Homo sapiens]
Length = 629
Score = 28.5 bits (62), Expect = 7.8
Identities = 20/87 (22%), Positives = 35/87 (40%), Gaps = 17/87 (19%)
Query: 182 PLFAEAVDSIFSYSALLWAWCTVNTRAVYLRPRQRECLSAEPDTCALAPYLDLLNHSPHV 241
PL +VD I +Y + VY ++R A P + +LNH
Sbjct: 44 PLRKLSVDLIKTYKHI---------NEVYYAKKKRRAQQAPPQDSSNKKEKKVLNHG--- 91
Query: 242 QVKAAFNEETHSYEIRTTSRWRKHEEV 268
++++ H Y +R+ RW + E+
Sbjct: 92 -----YDDDNHDYIVRSGERWLERYEI 113
>gi|5922001 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1B isoform c [Homo sapiens]
Length = 601
Score = 28.5 bits (62), Expect = 7.8
Identities = 20/87 (22%), Positives = 35/87 (40%), Gaps = 17/87 (19%)
Query: 182 PLFAEAVDSIFSYSALLWAWCTVNTRAVYLRPRQRECLSAEPDTCALAPYLDLLNHSPHV 241
PL +VD I +Y + VY ++R A P + +LNH
Sbjct: 44 PLRKLSVDLIKTYKHI---------NEVYYAKKKRRAQQAPPQDSSNKKEKKVLNHG--- 91
Query: 242 QVKAAFNEETHSYEIRTTSRWRKHEEV 268
++++ H Y +R+ RW + E+
Sbjct: 92 -----YDDDNHDYIVRSGERWLERYEI 113
>gi|5921999 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1B isoform b [Homo sapiens]
Length = 589
Score = 28.5 bits (62), Expect = 7.8
Identities = 20/87 (22%), Positives = 35/87 (40%), Gaps = 17/87 (19%)
Query: 182 PLFAEAVDSIFSYSALLWAWCTVNTRAVYLRPRQRECLSAEPDTCALAPYLDLLNHSPHV 241
PL +VD I +Y + VY ++R A P + +LNH
Sbjct: 44 PLRKLSVDLIKTYKHI---------NEVYYAKKKRRAQQAPPQDSSNKKEKKVLNHG--- 91
Query: 242 QVKAAFNEETHSYEIRTTSRWRKHEEV 268
++++ H Y +R+ RW + E+
Sbjct: 92 -----YDDDNHDYIVRSGERWLERYEI 113
>gi|144953913 zinc finger protein 714 [Homo sapiens]
Length = 555
Score = 28.5 bits (62), Expect = 7.8
Identities = 19/63 (30%), Positives = 26/63 (41%)
Query: 3 KGKGRTSRIRRRKLCGSSESRGVNESHKSEFIELRKWLKARKFQDSNLAPACFPGTGRGL 62
K R+S + + + + E E F + K RK Q +A AC P T RGL
Sbjct: 460 KAFNRSSNLTKHNIIHTGEKSYKCEECGKAFNQSSTLTKHRKIQQGMVAHACNPNTLRGL 519
Query: 63 MSQ 65
Q
Sbjct: 520 GEQ 522
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.134 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,887,933
Number of Sequences: 37866
Number of extensions: 567949
Number of successful extensions: 1384
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1370
Number of HSP's gapped (non-prelim): 17
length of query: 307
length of database: 18,247,518
effective HSP length: 102
effective length of query: 205
effective length of database: 14,385,186
effective search space: 2948963130
effective search space used: 2948963130
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.