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Search of human proteins with 5454030
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5454030 RAS-related on chromosome 22 isoform a [Homo
sapiens]
(203 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5454030 RAS-related on chromosome 22 isoform a [Homo sapiens] 422 e-118
gi|55953120 RAS-related on chromosome 22 isoform b [Homo sapiens] 240 5e-64
gi|15277321 RAS-like, family 10, member B [Homo sapiens] 197 5e-51
gi|21703367 Di-Ras2 [Homo sapiens] 88 6e-18
gi|21553323 DIRAS family, GTP-binding RAS-like 1 [Homo sapiens] 83 1e-16
gi|7706359 RAS, dexamethasone-induced 1 [Homo sapiens] 82 2e-16
gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens] 80 1e-15
gi|22027486 RASD family, member 2 [Homo sapiens] 79 2e-15
gi|10518344 RAP2A, member of RAS oncogene family [Homo sapiens] 77 8e-15
gi|4506405 v-ral simian leukemia viral oncogene homolog B [Homo ... 77 1e-14
gi|32129209 RAP2C, member of RAS oncogene family [Homo sapiens] 76 2e-14
gi|5902050 Ras-like without CAAX 1 [Homo sapiens] 74 1e-13
gi|58219792 RAP1B, member of RAS oncogene family [Homo sapiens] 73 2e-13
gi|7661678 RAP1B, member of RAS oncogene family [Homo sapiens] 73 2e-13
gi|58331202 RAP1A, member of RAS oncogene family [Homo sapiens] 72 2e-13
gi|4506413 RAP1A, member of RAS oncogene family [Homo sapiens] 72 2e-13
gi|33946329 ras related v-ral simian leukemia viral oncogene hom... 68 6e-12
gi|5032041 Ras homolog enriched in brain [Homo sapiens] 68 6e-12
gi|4506533 Ras-like without CAAX 2 [Homo sapiens] 64 9e-11
gi|4757770 ras homolog gene family, member H [Homo sapiens] 62 3e-10
gi|34147513 RAB7, member RAS oncogene family [Homo sapiens] 62 3e-10
gi|192807327 Ras-related associated with diabetes [Homo sapiens] 62 3e-10
gi|4759054 Ras-related associated with diabetes [Homo sapiens] 62 3e-10
gi|229577148 ras homolog gene family, member V [Homo sapiens] 61 7e-10
gi|45592963 RAS-like, family 11, member A [Homo sapiens] 61 7e-10
gi|20070266 RAS-like GTP-binding protein REM [Homo sapiens] 60 1e-09
gi|194363762 v-Ha-ras Harvey rat sarcoma viral oncogene homolog ... 59 3e-09
gi|4885425 v-Ha-ras Harvey rat sarcoma viral oncogene homolog is... 59 3e-09
gi|21389385 Ras homolog enriched in brain like 1 [Homo sapiens] 58 6e-09
gi|4757772 DIRAS family, GTP-binding RAS-like 3 [Homo sapiens] 57 8e-09
>gi|5454030 RAS-related on chromosome 22 isoform a [Homo sapiens]
Length = 203
Score = 422 bits (1084), Expect = e-118
Identities = 203/203 (100%), Positives = 203/203 (100%)
Query: 1 MGGSLRVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDG 60
MGGSLRVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDG
Sbjct: 1 MGGSLRVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDG 60
Query: 61 DVAGPGSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAGAP 120
DVAGPGSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAGAP
Sbjct: 61 DVAGPGSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAGAP 120
Query: 121 EAPILVVGNKRDRQRLRFGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELLRCALV 180
EAPILVVGNKRDRQRLRFGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELLRCALV
Sbjct: 121 EAPILVVGNKRDRQRLRFGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELLRCALV 180
Query: 181 RARPAHPALRLQGALHPARCSLM 203
RARPAHPALRLQGALHPARCSLM
Sbjct: 181 RARPAHPALRLQGALHPARCSLM 203
>gi|55953120 RAS-related on chromosome 22 isoform b [Homo sapiens]
Length = 115
Score = 240 bits (613), Expect = 5e-64
Identities = 115/115 (100%), Positives = 115/115 (100%)
Query: 1 MGGSLRVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDG 60
MGGSLRVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDG
Sbjct: 1 MGGSLRVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDG 60
Query: 61 DVAGPGSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETR 115
DVAGPGSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETR
Sbjct: 61 DVAGPGSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETR 115
>gi|15277321 RAS-like, family 10, member B [Homo sapiens]
Length = 203
Score = 197 bits (501), Expect = 5e-51
Identities = 105/204 (51%), Positives = 134/204 (65%), Gaps = 2/204 (0%)
Query: 1 MGGSLRVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDG 60
M + RVAVLGA GVGK+AI+RQFL+ ++ E PT RLY PAV+++G V+DL I D
Sbjct: 1 MVSTYRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDF 60
Query: 61 DVAGPGSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAGAP 120
+EW D L+ A++LVYDIC DSF+YVK +RQ+I ETR G
Sbjct: 61 PPIS-AFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTS 119
Query: 121 EAPILVVGNKRDRQRLRFGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELLR-CAL 179
E PI++VGNKRD QR R PR ++ LVR+ W+CGY+ECSAKYNWH+L LF ELL+
Sbjct: 120 ETPIIIVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSVGC 179
Query: 180 VRARPAHPALRLQGALHPARCSLM 203
R + H ALR QGAL RC++M
Sbjct: 180 ARCKHVHAALRFQGALRRNRCAIM 203
>gi|21703367 Di-Ras2 [Homo sapiens]
Length = 199
Score = 87.8 bits (216), Expect = 6e-18
Identities = 59/170 (34%), Positives = 88/170 (51%), Gaps = 12/170 (7%)
Query: 6 RVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDGDVAGP 65
RVAV GA GVGK++++ +F+ G + E + PT YR + D ++ L I D
Sbjct: 9 RVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDT-YRQVISCDKSICTLQITDTT---- 63
Query: 66 GSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAGAPEAPIL 125
G ++P + S+ AF+LVY I S S + +K + ++I E + PI+
Sbjct: 64 -----GSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIK-GDVESIPIM 117
Query: 126 VVGNKRDRQRLRFGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELL 175
+VGNK D R AL R W+C ++E SAK N +V LF+ELL
Sbjct: 118 LVGNKCDESPSREVQSSEAEALART-WKCAFMETSAKLNHNVKELFQELL 166
>gi|21553323 DIRAS family, GTP-binding RAS-like 1 [Homo sapiens]
Length = 198
Score = 83.2 bits (204), Expect = 1e-16
Identities = 53/170 (31%), Positives = 89/170 (52%), Gaps = 13/170 (7%)
Query: 6 RVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDGDVAGP 65
RV V GA GVGK++++ +F+ G + + + PT YR + D +V L I D
Sbjct: 9 RVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDT-YRQVISCDKSVCTLQITDTT---- 63
Query: 66 GSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAGAPEAPIL 125
G ++P + S+ AF+LV+ + S S + + + + I + + + P++
Sbjct: 64 -----GSHQFPAMQRLSISKGHAFILVFSVTSKQSLEELGPIYKLIVQIK-GSVEDIPVM 117
Query: 126 VVGNKRDRQRLRFGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELL 175
+VGNK D + R A A V + W+C ++E SAK N++V LF+ELL
Sbjct: 118 LVGNKCDETQREVDTREAQA--VAQEWKCAFMETSAKMNYNVKELFQELL 165
>gi|7706359 RAS, dexamethasone-induced 1 [Homo sapiens]
Length = 281
Score = 82.4 bits (202), Expect = 2e-16
Identities = 59/180 (32%), Positives = 90/180 (50%), Gaps = 17/180 (9%)
Query: 6 RVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDGDVAGP 65
R+ +LG+ VGKTAI+ +FL G + + + PT +R + G VY L I D
Sbjct: 26 RMVILGSSKVGKTAIVSRFLTGRFEDAYTPTIED-FHRKFYSIRGEVYQLDILD------ 78
Query: 66 GSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPA------GA 119
G +P + S+ D F+LV+ + + DSF+ V+ LRQ+I +T+
Sbjct: 79 ---TSGNHPFPAMRRLSILTGDVFILVFSLDNRDSFEEVQRLRQQILDTKSCLKNKTKEN 135
Query: 120 PEAPILVVGNKRDRQRLRFGPRRALAALVRRG-WRCGYLECSAKYNWHVLRLFRELLRCA 178
+ P+++ GNK DR R +R + LV RC Y E SAK N + ++FR L A
Sbjct: 136 VDVPLVICGNKGDRDFYREVDQREIEQLVGDDPQRCAYFEISAKKNSSLDQMFRALFAMA 195
>gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 80.1 bits (196), Expect = 1e-15
Identities = 57/182 (31%), Positives = 92/182 (50%), Gaps = 19/182 (10%)
Query: 6 RVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDGDVAGP 65
+V VLG+ GVGK+A+ QF+ G + E++ PT YR + +D + L I D
Sbjct: 5 KVVVLGSGGVGKSALTVQFVTGSFIEKYDPTI-EDFYRKEIEVDSSPSVLEILD------ 57
Query: 66 GSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAGAPEAPIL 125
G E++ +D +++ F+LVY + + SF +K +R +I R P++
Sbjct: 58 ---TAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQI--IRVKRYERVPMI 112
Query: 126 VVGNKRD---RQRLRFGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELLRCALVRA 182
+VGNK D + + +G +ALA W C ++E SAK V LF E++R A
Sbjct: 113 LVGNKVDLEGEREVSYGEGKALA----EEWSCPFMETSAKNKASVDELFAEIVRQMNYAA 168
Query: 183 RP 184
+P
Sbjct: 169 QP 170
>gi|22027486 RASD family, member 2 [Homo sapiens]
Length = 266
Score = 79.3 bits (194), Expect = 2e-15
Identities = 59/182 (32%), Positives = 88/182 (48%), Gaps = 17/182 (9%)
Query: 4 SLRVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDGDVA 63
S R+ VLGA VGK++I+ +FL G + +++ PT +R + G +Y L I D
Sbjct: 19 SYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTI-EDFHRKVYNIRGDMYQLDILD---- 73
Query: 64 GPGSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPA------ 117
G +P + S+ D F+LV+ + + +SFD VK L+++I E +
Sbjct: 74 -----TSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTK 128
Query: 118 GAPEAPILVVGNKRDRQRL-RFGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELLR 176
A E P+++ GNK D L R P LV C Y E SAK N +V +F L
Sbjct: 129 EAAELPMVICGNKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVLFS 188
Query: 177 CA 178
A
Sbjct: 189 MA 190
>gi|10518344 RAP2A, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 77.4 bits (189), Expect = 8e-15
Identities = 57/182 (31%), Positives = 91/182 (50%), Gaps = 19/182 (10%)
Query: 6 RVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDGDVAGP 65
+V VLG+ GVGK+A+ QF+ G + E++ PT YR + +D + L I D
Sbjct: 5 KVVVLGSGGVGKSALTVQFVTGTFIEKYDPTI-EDFYRKEIEVDSSPSVLEILD------ 57
Query: 66 GSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAGAPEAPIL 125
G E++ +D +++ F+LVY + + SF +K +R +I R + P++
Sbjct: 58 ---TAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQI--IRVKRYEKVPVI 112
Query: 126 VVGNKRD---RQRLRFGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELLRCALVRA 182
+VGNK D + + RALA W C ++E SAK V LF E++R A
Sbjct: 113 LVGNKVDLESEREVSSSEGRALA----EEWGCPFMETSAKSKTMVDELFAEIVRQMNYAA 168
Query: 183 RP 184
+P
Sbjct: 169 QP 170
>gi|4506405 v-ral simian leukemia viral oncogene homolog B [Homo
sapiens]
Length = 206
Score = 76.6 bits (187), Expect = 1e-14
Identities = 52/171 (30%), Positives = 86/171 (50%), Gaps = 12/171 (7%)
Query: 6 RVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDGDVAGP 65
+V ++G+ GVGK+A+ QF++ ++ E + PT YR V+LDG + I D
Sbjct: 16 KVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADS-YRKKVVLDGEEVQIDILD------ 68
Query: 66 GSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAGAPEAPIL 125
G E++ +D + + F+LV+ I +SF R++I + A + P+L
Sbjct: 69 ---TAGQEDYAAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVK-AEEDKIPLL 124
Query: 126 VVGNKRDRQRLRFGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELLR 176
VVGNK D + R P + W Y+E SAK +V ++F +L+R
Sbjct: 125 VVGNKSDLEERRQVPVEEARSKAEE-WGVQYVETSAKTRANVDKVFFDLMR 174
>gi|32129209 RAP2C, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 76.3 bits (186), Expect = 2e-14
Identities = 55/174 (31%), Positives = 89/174 (51%), Gaps = 19/174 (10%)
Query: 6 RVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDGDVAGP 65
+V VLG+ GVGK+A+ QF+ G + E++ PT YR + +D + L I D
Sbjct: 5 KVVVLGSGGVGKSALTVQFVTGTFIEKYDPTI-EDFYRKEIEVDSSPSVLEILD------ 57
Query: 66 GSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAGAPEAPIL 125
G E++ +D +++ F+LVY + + SF +K +R +I R + P++
Sbjct: 58 ---TAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQI--VRVKRYEKVPLI 112
Query: 126 VVGNKRD---RQRLRFGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELLR 176
+VGNK D + + RALA + W C ++E SAK V LF E++R
Sbjct: 113 LVGNKVDLEPEREVMSSEGRALA----QEWGCPFMETSAKSKSMVDELFAEIVR 162
>gi|5902050 Ras-like without CAAX 1 [Homo sapiens]
Length = 219
Score = 73.6 bits (179), Expect = 1e-13
Identities = 51/171 (29%), Positives = 85/171 (49%), Gaps = 13/171 (7%)
Query: 6 RVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDGDVAGP 65
++ +LGA GVGK+A+ QF+ +PE H PT Y+ + +D +L I D
Sbjct: 23 KLVMLGAGGVGKSAMTMQFISHRFPEDHDPTI-EDAYKIRIRIDDEPANLDILD------ 75
Query: 66 GSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAGAPEAPIL 125
G E+ +D ++ + F++ Y I SF V+ +Q I R + P++
Sbjct: 76 ---TAGQAEFTAMRDQYMRAGEGFIICYSITDRRSFHEVREFKQLIYRVR--RTDDTPVV 130
Query: 126 VVGNKRDRQRLRFGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELLR 176
+VGNK D ++LR + AL R + C + E SA Y +++ +F L+R
Sbjct: 131 LVGNKSDLKQLRQVTKEEGLALARE-FSCPFFETSAAYRYYIDDVFHALVR 180
>gi|58219792 RAP1B, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 72.8 bits (177), Expect = 2e-13
Identities = 52/171 (30%), Positives = 88/171 (51%), Gaps = 12/171 (7%)
Query: 6 RVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDGDVAGP 65
++ VLG+ GVGK+A+ QF+ G + E++ PT YR V +D L I D
Sbjct: 5 KLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDS-YRKQVEVDAQQCMLEILD------ 57
Query: 66 GSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAGAPEAPIL 125
G E++ +D +++ F LVY I + +F+ ++ LR++I + + P++
Sbjct: 58 ---TAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTD--DVPMI 112
Query: 126 VVGNKRDRQRLRFGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELLR 176
+VGNK D + R + L R+ C +LE SAK +V +F +L+R
Sbjct: 113 LVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVR 163
>gi|7661678 RAP1B, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 72.8 bits (177), Expect = 2e-13
Identities = 52/171 (30%), Positives = 88/171 (51%), Gaps = 12/171 (7%)
Query: 6 RVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDGDVAGP 65
++ VLG+ GVGK+A+ QF+ G + E++ PT YR V +D L I D
Sbjct: 5 KLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDS-YRKQVEVDAQQCMLEILD------ 57
Query: 66 GSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAGAPEAPIL 125
G E++ +D +++ F LVY I + +F+ ++ LR++I + + P++
Sbjct: 58 ---TAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTD--DVPMI 112
Query: 126 VVGNKRDRQRLRFGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELLR 176
+VGNK D + R + L R+ C +LE SAK +V +F +L+R
Sbjct: 113 LVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVR 163
>gi|58331202 RAP1A, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 72.4 bits (176), Expect = 2e-13
Identities = 52/171 (30%), Positives = 88/171 (51%), Gaps = 12/171 (7%)
Query: 6 RVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDGDVAGP 65
++ VLG+ GVGK+A+ QF+ G + E++ PT YR V +D L I D
Sbjct: 5 KLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDS-YRKQVEVDCQQCMLEILD------ 57
Query: 66 GSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAGAPEAPIL 125
G E++ +D +++ F LVY I + +F+ ++ LR++I + + P++
Sbjct: 58 ---TAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDT--EDVPMI 112
Query: 126 VVGNKRDRQRLRFGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELLR 176
+VGNK D + R + L R+ C +LE SAK +V +F +L+R
Sbjct: 113 LVGNKCDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVR 163
>gi|4506413 RAP1A, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 72.4 bits (176), Expect = 2e-13
Identities = 52/171 (30%), Positives = 88/171 (51%), Gaps = 12/171 (7%)
Query: 6 RVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDGDVAGP 65
++ VLG+ GVGK+A+ QF+ G + E++ PT YR V +D L I D
Sbjct: 5 KLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDS-YRKQVEVDCQQCMLEILD------ 57
Query: 66 GSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAGAPEAPIL 125
G E++ +D +++ F LVY I + +F+ ++ LR++I + + P++
Sbjct: 58 ---TAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDT--EDVPMI 112
Query: 126 VVGNKRDRQRLRFGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELLR 176
+VGNK D + R + L R+ C +LE SAK +V +F +L+R
Sbjct: 113 LVGNKCDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVR 163
>gi|33946329 ras related v-ral simian leukemia viral oncogene
homolog A [Homo sapiens]
Length = 206
Score = 67.8 bits (164), Expect = 6e-12
Identities = 52/180 (28%), Positives = 88/180 (48%), Gaps = 19/180 (10%)
Query: 6 RVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDGDVAGP 65
+V ++G+ GVGK+A+ QF++ ++ E + PT YR V+LDG + I D
Sbjct: 16 KVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADS-YRKKVVLDGEEVQIDILD------ 68
Query: 66 GSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAGAPEAPIL 125
G E++ +D + + F+ V+ I +SF R++I + P L
Sbjct: 69 ---TAGQEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKE--DENVPFL 123
Query: 126 VVGNKRDRQRLRFGPRRALAALVRRG--WRCGYLECSAKYNWHVLRLFRELLRCALVRAR 183
+VGNK D + R + ++ R W Y+E SAK +V ++F +L+R +RAR
Sbjct: 124 LVGNKSDLEDKR---QVSVEEAKNRAEQWNVNYVETSAKTRANVDKVFFDLMR--EIRAR 178
>gi|5032041 Ras homolog enriched in brain [Homo sapiens]
Length = 184
Score = 67.8 bits (164), Expect = 6e-12
Identities = 46/175 (26%), Positives = 86/175 (49%), Gaps = 19/175 (10%)
Query: 4 SLRVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDGDVA 63
S ++A+LG VGK+++ QF+ G + + + PT + + ++G Y L + D
Sbjct: 6 SRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTI-ENTFTKLITVNGQEYHLQLVD---- 60
Query: 64 GPGSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAGAPEAP 123
G +E+ D + ++LVY + S SF+ +K + ++ + G + P
Sbjct: 61 -----TAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDM--VGKVQIP 113
Query: 124 ILVVGNKRD---RQRLRFGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELL 175
I++VGNK+D + + + +ALA W +LE SAK N + +FR ++
Sbjct: 114 IMLVGNKKDLHMERVISYEEGKALA----ESWNAAFLESSAKENQTAVDVFRRII 164
>gi|4506533 Ras-like without CAAX 2 [Homo sapiens]
Length = 217
Score = 63.9 bits (154), Expect = 9e-11
Identities = 52/190 (27%), Positives = 89/190 (46%), Gaps = 17/190 (8%)
Query: 2 GGS--LRVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRD 59
GGS +V +LGA GVGK+A+ QF+ +P+ H PT Y+ V +D L I D
Sbjct: 16 GGSREYKVVMLGAGGVGKSAMTMQFISHQFPDYHDPTI-EDAYKTQVRIDNEPAYLDILD 74
Query: 60 GDVAGPGSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAGA 119
G E+ ++ ++ + F++ Y + SF ++ I + R
Sbjct: 75 ---------TAGQAEFTAMREQYMRGGEGFIICYSVTDRQSFQEAAKFKELIFQVR--HT 123
Query: 120 PEAPILVVGNKRDRQRLRFGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELLRCAL 179
E P+++VGNK D ++ R +L + + CG+ E SA + + F L+R
Sbjct: 124 YEIPLVLVGNKIDLEQFRQVSTEEGLSLAQE-YNCGFFETSAALRFCIDDAFHGLVR--E 180
Query: 180 VRARPAHPAL 189
+R + + P+L
Sbjct: 181 IRKKESMPSL 190
>gi|4757770 ras homolog gene family, member H [Homo sapiens]
Length = 191
Score = 62.4 bits (150), Expect = 3e-10
Identities = 54/193 (27%), Positives = 90/193 (46%), Gaps = 28/193 (14%)
Query: 1 MGGSLRVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPA---VLLDGAVYDLSI 57
M S++ ++G VGKT+++ +F +PE ++PT +Y V +DG L +
Sbjct: 1 MLSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPT----VYENTGVDVFMDGIQISLGL 56
Query: 58 RDGDVAGPGSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPA 117
D G + + + S Q D ++ Y + + +SF +K + I E R +
Sbjct: 57 WD---------TAGNDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLK--NKWIGEIR-S 104
Query: 118 GAPEAPILVVGNKRDRQRLRFGPRRALAALVRRGWRC-------GYLECSAKYNWHVLRL 170
P P+LVV + D++ + GP RA G + GYLECSA N V ++
Sbjct: 105 NLPCTPVLVVATQTDQREM--GPHRASCVNAMEGKKLAQDVRAKGYLECSALSNRGVQQV 162
Query: 171 FRELLRCALVRAR 183
F +R A+ +AR
Sbjct: 163 FECAVRTAVNQAR 175
>gi|34147513 RAB7, member RAS oncogene family [Homo sapiens]
Length = 207
Score = 62.4 bits (150), Expect = 3e-10
Identities = 46/176 (26%), Positives = 82/176 (46%), Gaps = 11/176 (6%)
Query: 5 LRVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDGDVAG 64
L+V +LG GVGKT+++ Q++ + +++ T G V++D + + I D
Sbjct: 9 LKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWD----- 63
Query: 65 PGSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQR-IAETRPAGAPEAP 123
G E + + D VLV+D+ +P++F + + R + + P P
Sbjct: 64 ----TAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFP 119
Query: 124 ILVVGNKRDRQRLRFGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELLRCAL 179
+V+GNK D + + +RA A + Y E SAK +V + F+ + R AL
Sbjct: 120 FVVLGNKIDLENRQVATKRAQAWCYSKN-NIPYFETSAKEAINVEQAFQTIARNAL 174
>gi|192807327 Ras-related associated with diabetes [Homo sapiens]
Length = 308
Score = 62.0 bits (149), Expect = 3e-10
Identities = 53/179 (29%), Positives = 83/179 (46%), Gaps = 30/179 (16%)
Query: 6 RVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDG-----AVYDLSIRDG 60
+V +LGAPGVGK+A+ R +FG + Y ++++DG VYD+ +DG
Sbjct: 93 KVLLLGAPGVGKSALAR--IFGGVEDGPEAEAAGHTYDRSIVVDGEEASLMVYDIWEQDG 150
Query: 61 DVAGPGSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAGAP 120
PG + DA+V+VY + SF+ LR ++ R
Sbjct: 151 GRWLPGH--------------CMAMGDAYVIVYSVTDKGSFEKASELRVQLRRARQ--TD 194
Query: 121 EAPILVVGNKRDRQRLR---FGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELLR 176
+ PI++VGNK D R R RA A + + C ++E SA + +V LF ++R
Sbjct: 195 DVPIILVGNKSDLVRSREVSVDEGRACAVV----FDCKFIETSAALHHNVQALFEGVVR 249
>gi|4759054 Ras-related associated with diabetes [Homo sapiens]
Length = 308
Score = 62.0 bits (149), Expect = 3e-10
Identities = 53/179 (29%), Positives = 83/179 (46%), Gaps = 30/179 (16%)
Query: 6 RVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDG-----AVYDLSIRDG 60
+V +LGAPGVGK+A+ R +FG + Y ++++DG VYD+ +DG
Sbjct: 93 KVLLLGAPGVGKSALAR--IFGGVEDGPEAEAAGHTYDRSIVVDGEEASLMVYDIWEQDG 150
Query: 61 DVAGPGSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAGAP 120
PG + DA+V+VY + SF+ LR ++ R
Sbjct: 151 GRWLPGH--------------CMAMGDAYVIVYSVTDKGSFEKASELRVQLRRARQ--TD 194
Query: 121 EAPILVVGNKRDRQRLR---FGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELLR 176
+ PI++VGNK D R R RA A + + C ++E SA + +V LF ++R
Sbjct: 195 DVPIILVGNKSDLVRSREVSVDEGRACAVV----FDCKFIETSAALHHNVQALFEGVVR 249
>gi|229577148 ras homolog gene family, member V [Homo sapiens]
Length = 236
Score = 60.8 bits (146), Expect = 7e-10
Identities = 55/212 (25%), Positives = 90/212 (42%), Gaps = 32/212 (15%)
Query: 5 LRVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDGDVAG 64
++ ++G VGK+++I + YP R+RPT + VL+DGA + + D
Sbjct: 32 IKCVLVGDGAVGKSSLIVSYTCNGYPARYRPT-ALDTFSVQVLVDGAPVRIELWD----- 85
Query: 65 PGSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAGAPEAPI 124
G E++ + DTD F+ + + P SF + + + E R P+AP+
Sbjct: 86 ----TAGQEDFDRLRSLCYPDTDVFLACFSVVQPSSFQNI--TEKWLPEIRTHN-PQAPV 138
Query: 125 LVVGNKRD-----------RQRLRFGP-----RRALAALVRRGWRCGYLECSAKYNWHVL 168
L+VG + D Q R GP + LA +R C YLECSA ++
Sbjct: 139 LLVGTQADLRDDVNVLIQLDQGGREGPVPQPQAQGLAEKIR---ACCYLECSALTQKNLK 195
Query: 169 RLFRELLRCALVRARPAHPALRLQGALHPARC 200
+F + A+ L +G +RC
Sbjct: 196 EVFDSAILSAIEHKARLEKKLNAKGVRTLSRC 227
>gi|45592963 RAS-like, family 11, member A [Homo sapiens]
Length = 242
Score = 60.8 bits (146), Expect = 7e-10
Identities = 44/134 (32%), Positives = 71/134 (52%), Gaps = 17/134 (12%)
Query: 5 LRVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDGDVAG 64
+++AVLGA VGK+A+I +FL + + P G +LY V ++G L I+D
Sbjct: 28 IKLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTG-KLYSRLVYVEGDQLSLQIQD----- 81
Query: 65 PGSSPGGPE------EWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAG 118
+PGG + + D+ +Q + F+LVY I DS+ ++ L Q I + P
Sbjct: 82 ---TPGGVQIQDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVHPDS 138
Query: 119 APEAPILVVGNKRD 132
+AP+++VGNK D
Sbjct: 139 --KAPVIIVGNKGD 150
>gi|20070266 RAS-like GTP-binding protein REM [Homo sapiens]
Length = 298
Score = 60.1 bits (144), Expect = 1e-09
Identities = 54/181 (29%), Positives = 82/181 (45%), Gaps = 17/181 (9%)
Query: 6 RVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDGDVAGP 65
RV +LG PGVGKT++ F + H G +Y + +DG L + D
Sbjct: 82 RVVLLGDPGVGKTSLASLFAGKQERDLHEQL-GEDVYERTLTVDGEDTTLVVVD-----T 135
Query: 66 GSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAGAPEAPIL 125
+ + W +++ LQ A+V+VY I SF+ LR ++ T A PI+
Sbjct: 136 WEAEKLDKSW--SQESCLQGGSAYVIVYSIADRGSFESASELRIQLRRTHQ--ADHVPII 191
Query: 126 VVGNKRDRQRLR---FGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELLRCALVRA 182
+VGNK D R R RA A + + C ++E SA +V LF ++R +R
Sbjct: 192 LVGNKADLARCREVSVEEGRACAVV----FDCKFIETSATLQHNVAELFEGVVRQLRLRR 247
Query: 183 R 183
R
Sbjct: 248 R 248
>gi|194363762 v-Ha-ras Harvey rat sarcoma viral oncogene homolog
isoform 1 [Homo sapiens]
Length = 189
Score = 58.9 bits (141), Expect = 3e-09
Identities = 49/171 (28%), Positives = 82/171 (47%), Gaps = 14/171 (8%)
Query: 6 RVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDGDVAGP 65
++ V+GA GVGK+A+ Q + + + + PT YR V++DG L I D
Sbjct: 5 KLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDS-YRKQVVIDGETCLLDILD------ 57
Query: 66 GSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAGAPEAPIL 125
G EE+ +D ++ + F+ V+ I + SF+ + R++I R + + P++
Sbjct: 58 ---TAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQI--KRVKDSDDVPMV 112
Query: 126 VVGNKRDRQRLRFGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELLR 176
+VGNK D R+A + R + Y+E SAK V F L+R
Sbjct: 113 LVGNKCDLAARTVESRQAQD--LARSYGIPYIETSAKTRQGVEDAFYTLVR 161
>gi|4885425 v-Ha-ras Harvey rat sarcoma viral oncogene homolog
isoform 1 [Homo sapiens]
Length = 189
Score = 58.9 bits (141), Expect = 3e-09
Identities = 49/171 (28%), Positives = 82/171 (47%), Gaps = 14/171 (8%)
Query: 6 RVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDGDVAGP 65
++ V+GA GVGK+A+ Q + + + + PT YR V++DG L I D
Sbjct: 5 KLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDS-YRKQVVIDGETCLLDILD------ 57
Query: 66 GSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAGAPEAPIL 125
G EE+ +D ++ + F+ V+ I + SF+ + R++I R + + P++
Sbjct: 58 ---TAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQI--KRVKDSDDVPMV 112
Query: 126 VVGNKRDRQRLRFGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELLR 176
+VGNK D R+A + R + Y+E SAK V F L+R
Sbjct: 113 LVGNKCDLAARTVESRQAQD--LARSYGIPYIETSAKTRQGVEDAFYTLVR 161
>gi|21389385 Ras homolog enriched in brain like 1 [Homo sapiens]
Length = 183
Score = 57.8 bits (138), Expect = 6e-09
Identities = 46/175 (26%), Positives = 80/175 (45%), Gaps = 21/175 (12%)
Query: 6 RVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDGDVAGP 65
+V +LG VGKT++ QF+ G++ E + PT Y V L + L + D
Sbjct: 8 KVVILGYRCVGKTSLAHQFVEGEFSEGYDPT-VENTYSKIVTLGKDEFHLHLVD------ 60
Query: 66 GSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAGAPEAPIL 125
G +E+ + +VLVY + S SF +++L Q++ E G P++
Sbjct: 61 ---TAGQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGH--GKTRVPVV 115
Query: 126 VVGNKRDRQRLRFGPRRALAAL----VRRGWRCGYLECSAKYNWHVLRLFRELLR 176
+VGNK D P R + A+ + W ++E SA+ N +F ++++
Sbjct: 116 LVGNKAD-----LSPEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQ 165
>gi|4757772 DIRAS family, GTP-binding RAS-like 3 [Homo sapiens]
Length = 229
Score = 57.4 bits (137), Expect = 8e-09
Identities = 45/170 (26%), Positives = 75/170 (44%), Gaps = 12/170 (7%)
Query: 6 RVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDGDVAGP 65
RV V+G GVGK+ ++ ++ G++ + PT Y + V L I D +G
Sbjct: 39 RVVVVGTAGVGKSTLLHKWASGNFRHEYLPTI-ENTYCQLLGCSHGVLSLHITDSK-SGD 96
Query: 66 GSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAGAPEAPIL 125
G+ + + AFVLVY + ++ + +KA + I + + + PI+
Sbjct: 97 GNRA--------LQRHVIARGHAFVLVYSVTKKETLEELKAFYELICKIKGNNLHKFPIV 148
Query: 126 VVGNKRDRQRLRFGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELL 175
+VGNK D + W C ++E SAK + +V LF LL
Sbjct: 149 LVGNKSDDTHREVALNDGATCAME--WNCAFMEISAKTDVNVQELFHMLL 196
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.142 0.460
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,501,934
Number of Sequences: 37866
Number of extensions: 479716
Number of successful extensions: 1974
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 95
Number of HSP's successfully gapped in prelim test: 110
Number of HSP's that attempted gapping in prelim test: 1688
Number of HSP's gapped (non-prelim): 218
length of query: 203
length of database: 18,247,518
effective HSP length: 97
effective length of query: 106
effective length of database: 14,574,516
effective search space: 1544898696
effective search space used: 1544898696
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.