Search of human proteins with 5453886

Search of human proteins with 5453886

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5453886 serpin peptidase inhibitor, clade I (pancpin),
member 2 [Homo sapiens]
         (405 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member...   794   0.0  
gi|170295807 neuroserpin precursor [Homo sapiens]                     316   2e-86
gi|4826904 neuroserpin precursor [Homo sapiens]                       316   2e-86
gi|5902072 serine (or cysteine) proteinase inhibitor, clade B (o...   249   3e-66
gi|28076869 serine (or cysteine) proteinase inhibitor, clade B (...   243   2e-64
gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Hom...   234   8e-62
gi|41152086 serine (or cysteine) proteinase inhibitor, clade B (...   229   3e-60
gi|17998551 serine (or cysteine) proteinase inhibitor, clade B (...   228   6e-60
gi|13489087 serine (or cysteine) proteinase inhibitor, clade B (...   219   5e-57
gi|211904156 plasminogen activator inhibitor type 1, member 2 is...   214   1e-55
gi|211904154 plasminogen activator inhibitor type 1, member 2 is...   214   1e-55
gi|211904152 plasminogen activator inhibitor type 1, member 2 is...   214   1e-55
gi|24307907 plasminogen activator inhibitor type 1, member 2 iso...   211   7e-55
gi|8393956 serine (or cysteine) proteinase inhibitor, clade B (o...   207   1e-53
gi|10835159 plasminogen activator inhibitor-1 [Homo sapiens]          206   3e-53
gi|38504669 serine (or cysteine) proteinase inhibitor, clade B (...   206   4e-53
gi|38504673 serine (or cysteine) proteinase inhibitor, clade B (...   206   4e-53
gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo s...   205   7e-53
gi|4826902 serine (or cysteine) proteinase inhibitor, clade B (o...   204   1e-52
gi|50659080 serpin peptidase inhibitor, clade A, member 3 precur...   202   3e-52
gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo s...   193   2e-49
gi|219689110 serine (or cysteine) proteinase inhibitor, clade B ...   189   4e-48
gi|4505595 serine (or cysteine) proteinase inhibitor, clade B (o...   189   4e-48
gi|73858564 corticosteroid binding globulin precursor [Homo sapi...   178   7e-45
gi|189163542 serine proteinase inhibitor, clade A, member 1 [Hom...   175   8e-44
gi|189163540 serine proteinase inhibitor, clade A, member 1 [Hom...   175   8e-44
gi|189163538 serine proteinase inhibitor, clade A, member 1 [Hom...   175   8e-44
gi|189163536 serine proteinase inhibitor, clade A, member 1 [Hom...   175   8e-44
gi|189163534 serine proteinase inhibitor, clade A, member 1 [Hom...   175   8e-44
gi|189163532 serine proteinase inhibitor, clade A, member 1 [Hom...   175   8e-44

>gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member 2
           [Homo sapiens]
          Length = 405

 Score =  794 bits (2051), Expect = 0.0
 Identities = 405/405 (100%), Positives = 405/405 (100%)

Query: 1   MDTIFLWSLLLLFFGSQASRCSAQKNTEFAVDLYQEVSLSHKDNIIFSPLGITLVLEMVQ 60
           MDTIFLWSLLLLFFGSQASRCSAQKNTEFAVDLYQEVSLSHKDNIIFSPLGITLVLEMVQ
Sbjct: 1   MDTIFLWSLLLLFFGSQASRCSAQKNTEFAVDLYQEVSLSHKDNIIFSPLGITLVLEMVQ 60

Query: 61  LGAKGKAQQQIRQTLKQQETSAGEEFFVLKSFFSAISEKKQEFTFNLANALYLQEGFTVK 120
           LGAKGKAQQQIRQTLKQQETSAGEEFFVLKSFFSAISEKKQEFTFNLANALYLQEGFTVK
Sbjct: 61  LGAKGKAQQQIRQTLKQQETSAGEEFFVLKSFFSAISEKKQEFTFNLANALYLQEGFTVK 120

Query: 121 EQYLHGNKEFFQSAIKLVDFQDAKACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLV 180
           EQYLHGNKEFFQSAIKLVDFQDAKACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLV
Sbjct: 121 EQYLHGNKEFFQSAIKLVDFQDAKACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLV 180

Query: 181 NAIYFKGDWKQKFRKEDTQLINFTKKNGSTVKIPMMKALLRTKYGYFSESSLNYQVLELS 240
           NAIYFKGDWKQKFRKEDTQLINFTKKNGSTVKIPMMKALLRTKYGYFSESSLNYQVLELS
Sbjct: 181 NAIYFKGDWKQKFRKEDTQLINFTKKNGSTVKIPMMKALLRTKYGYFSESSLNYQVLELS 240

Query: 241 YKGDEFSLIIILPAEGMDIEEVEKLITAQQILKWLSEMQEEEVEISLPRFKVEQKVDFKD 300
           YKGDEFSLIIILPAEGMDIEEVEKLITAQQILKWLSEMQEEEVEISLPRFKVEQKVDFKD
Sbjct: 241 YKGDEFSLIIILPAEGMDIEEVEKLITAQQILKWLSEMQEEEVEISLPRFKVEQKVDFKD 300

Query: 301 VLYSLNITEIFSGGCDLSGITDSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSL 360
           VLYSLNITEIFSGGCDLSGITDSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSL
Sbjct: 301 VLYSLNITEIFSGGCDLSGITDSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSL 360

Query: 361 AQSQFIANHPFLFIMKHNPTESILFMGRVTNPDTQEIKGRDLDSL 405
           AQSQFIANHPFLFIMKHNPTESILFMGRVTNPDTQEIKGRDLDSL
Sbjct: 361 AQSQFIANHPFLFIMKHNPTESILFMGRVTNPDTQEIKGRDLDSL 405


>gi|170295807 neuroserpin precursor [Homo sapiens]
          Length = 410

 Score =  316 bits (810), Expect = 2e-86
 Identities = 159/405 (39%), Positives = 258/405 (63%), Gaps = 5/405 (1%)

Query: 6   LWSLLLLFFGSQASRCSAQKNTEFAVDLYQEVSLSHKD-NIIFSPLGITLVLEMVQLGAK 64
           L+SLL+L   +  +    +   + +V++Y  +  + +D NI+FSPL I L + M++LGA+
Sbjct: 6   LFSLLVLQSMATGATFPEEAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQ 65

Query: 65  GKAQQQIRQTLKQQETSAGEEFFVLKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYL 124
           G  Q++IR ++       GEEF  LK F + ++ K+ ++   +AN+L++Q GF V E++L
Sbjct: 66  GSTQKEIRHSMGYDSLKNGEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFL 125

Query: 125 HGNKEFFQSAIKLVDFQDAKACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIY 184
              K++F +A+  VDF    A A  I+ WVE  T+  +KD+ S  +F   T L L+NA+Y
Sbjct: 126 QMMKKYFNAAVNHVDFSQNVAVANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVY 185

Query: 185 FKGDWKQKFRKEDTQLINFTKKNGSTVKIPMMKALLRTKYGYFSESSLN----YQVLELS 240
           FKG+WK +FR E+T+  +FTK + S V+IPMM       YG FS+ S      YQVLE+ 
Sbjct: 186 FKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIP 245

Query: 241 YKGDEFSLIIILPAEGMDIEEVEKLITAQQILKWLSEMQEEEVEISLPRFKVEQKVDFKD 300
           Y+GDE S++++L  + + +  +E L+ AQ + +W + +++++VE+ LPRF VEQ++D KD
Sbjct: 246 YEGDEISMMLVLSRQEVPLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKD 305

Query: 301 VLYSLNITEIFSGGCDLSGITDSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSL 360
           VL +L ITEIF    +L+G++D+ E+++S+   K F E+NE+GSEAA  +G+     M++
Sbjct: 306 VLKALGITEIFIKDANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAV 365

Query: 361 AQSQFIANHPFLFIMKHNPTESILFMGRVTNPDTQEIKGRDLDSL 405
              Q I +HPF F++++  T +ILFMGRV +P+T    G D + L
Sbjct: 366 LYPQVIVDHPFFFLIRNRRTGTILFMGRVMHPETMNTSGHDFEEL 410


>gi|4826904 neuroserpin precursor [Homo sapiens]
          Length = 410

 Score =  316 bits (810), Expect = 2e-86
 Identities = 159/405 (39%), Positives = 258/405 (63%), Gaps = 5/405 (1%)

Query: 6   LWSLLLLFFGSQASRCSAQKNTEFAVDLYQEVSLSHKD-NIIFSPLGITLVLEMVQLGAK 64
           L+SLL+L   +  +    +   + +V++Y  +  + +D NI+FSPL I L + M++LGA+
Sbjct: 6   LFSLLVLQSMATGATFPEEAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQ 65

Query: 65  GKAQQQIRQTLKQQETSAGEEFFVLKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYL 124
           G  Q++IR ++       GEEF  LK F + ++ K+ ++   +AN+L++Q GF V E++L
Sbjct: 66  GSTQKEIRHSMGYDSLKNGEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFL 125

Query: 125 HGNKEFFQSAIKLVDFQDAKACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIY 184
              K++F +A+  VDF    A A  I+ WVE  T+  +KD+ S  +F   T L L+NA+Y
Sbjct: 126 QMMKKYFNAAVNHVDFSQNVAVANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVY 185

Query: 185 FKGDWKQKFRKEDTQLINFTKKNGSTVKIPMMKALLRTKYGYFSESSLN----YQVLELS 240
           FKG+WK +FR E+T+  +FTK + S V+IPMM       YG FS+ S      YQVLE+ 
Sbjct: 186 FKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIP 245

Query: 241 YKGDEFSLIIILPAEGMDIEEVEKLITAQQILKWLSEMQEEEVEISLPRFKVEQKVDFKD 300
           Y+GDE S++++L  + + +  +E L+ AQ + +W + +++++VE+ LPRF VEQ++D KD
Sbjct: 246 YEGDEISMMLVLSRQEVPLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKD 305

Query: 301 VLYSLNITEIFSGGCDLSGITDSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSL 360
           VL +L ITEIF    +L+G++D+ E+++S+   K F E+NE+GSEAA  +G+     M++
Sbjct: 306 VLKALGITEIFIKDANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAV 365

Query: 361 AQSQFIANHPFLFIMKHNPTESILFMGRVTNPDTQEIKGRDLDSL 405
              Q I +HPF F++++  T +ILFMGRV +P+T    G D + L
Sbjct: 366 LYPQVIVDHPFFFLIRNRRTGTILFMGRVMHPETMNTSGHDFEEL 410


>gi|5902072 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 3 [Homo sapiens]
          Length = 390

 Score =  249 bits (636), Expect = 3e-66
 Identities = 137/388 (35%), Positives = 226/388 (58%), Gaps = 20/388 (5%)

Query: 23  AQKNTEFAVDLYQEVSLSHKDNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETS- 81
           ++ NT+F  DL+Q+   S ++NI +SP+ IT  L MV LGAK    QQI++ L   + + 
Sbjct: 5   SEANTKFMFDLFQQFRKSKENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQVTE 64

Query: 82  -------------AGEEFFVLKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNK 128
                        +G      +   +  ++    +   +AN L+ ++ +   ++YL   K
Sbjct: 65  NTTGKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEYLDAIK 124

Query: 129 EFFQSAIKLVDFQDA-KACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKG 187
           +F+Q++++ VDF +A +   + I++WVE +T+ KIK++      G  T LVLVNAIYFKG
Sbjct: 125 KFYQTSVESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAIYFKG 184

Query: 188 DWKQKFRKEDTQLINFTKKNGSTVKIPMMKALLRTKYGYFSESSLNYQVLELSYKGDEFS 247
            W++KF KEDT+   F     +   I MM+    T + + S   +  +VLE+ YKG + S
Sbjct: 185 QWEKKFNKEDTKEEKFWPNKNTYKSIQMMRQY--TSFHFASLEDVQAKVLEIPYKGKDLS 242

Query: 248 LIIILPAEGMDIEEVEKLITAQQILKW--LSEMQEEEVEISLPRFKVEQKVDFKDVLYSL 305
           +I++LP E   ++++E+ +TA+++++W  L  M+E  V++ LPRFKVE+  D KD L ++
Sbjct: 243 MIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLKDTLRTM 302

Query: 306 NITEIFSGGCDLSGITDSSEVYVSQVTQKVFFEINEDGSEAATSTG-IHIPVIMSLAQSQ 364
            + +IF+G  DLSG+T S  + +S V  K F E+ E+G+EAA +T  +      +    +
Sbjct: 303 GMVDIFNGDADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSSPTSTNEE 362

Query: 365 FIANHPFLFIMKHNPTESILFMGRVTNP 392
           F  NHPFLF ++ N T SILF GR ++P
Sbjct: 363 FHCNHPFLFFIRQNKTNSILFYGRFSSP 390


>gi|28076869 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 4 [Homo sapiens]
          Length = 390

 Score =  243 bits (621), Expect = 2e-64
 Identities = 134/388 (34%), Positives = 224/388 (57%), Gaps = 20/388 (5%)

Query: 23  AQKNTEFAVDLYQEVSLSHKDNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETS- 81
           ++ NT+F  DL+Q+   S ++NI +SP+ IT  L MV LGAK    QQI + L   + + 
Sbjct: 5   SEANTKFMFDLFQQFRKSKENNIFYSPISITSALGMVLLGAKDNTAQQISKVLHFDQVTE 64

Query: 82  -------------AGEEFFVLKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNK 128
                        +G      +   +  ++    +   +AN L+ ++ +   ++YL   K
Sbjct: 65  NTTEKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEYLDAIK 124

Query: 129 EFFQSAIKLVDFQDA-KACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKG 187
           +F+Q++++  DF +A +   + I++WVE +T+ KIK++F     G  T LVLVNAIYFKG
Sbjct: 125 KFYQTSVESTDFANAPEESRKKINSWVESQTNEKIKNLFPDGTIGNDTTLVLVNAIYFKG 184

Query: 188 DWKQKFRKEDTQLINFTKKNGSTVKIPMMKALLRTKYGYFSESSLNYQVLELSYKGDEFS 247
            W+ KF+KE+T+   F     +   + MM+      + +     +  +VLE+ YKG + S
Sbjct: 185 QWENKFKKENTKEEKFWPNKNTYKSVQMMRQY--NSFNFALLEDVQAKVLEIPYKGKDLS 242

Query: 248 LIIILPAEGMDIEEVEKLITAQQILKW--LSEMQEEEVEISLPRFKVEQKVDFKDVLYSL 305
           +I++LP E   ++++E+ +TA+++++W  L  M+E  V++ LPRFK+E+  D KD L ++
Sbjct: 243 MIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETCVDLHLPRFKMEESYDLKDTLRTM 302

Query: 306 NITEIFSGGCDLSGITDSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMS-LAQSQ 364
            +  IF+G  DLSG+T S  + VS+V  K F E+ E+G EAA +T + +  + S     +
Sbjct: 303 GMVNIFNGDADLSGMTWSHGLSVSKVLHKAFVEVTEEGVEAAAATAVVVVELSSPSTNEE 362

Query: 365 FIANHPFLFIMKHNPTESILFMGRVTNP 392
           F  NHPFLF ++ N T SILF GR ++P
Sbjct: 363 FCCNHPFLFFIRQNKTNSILFYGRFSSP 390


>gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Homo
           sapiens]
          Length = 392

 Score =  234 bits (598), Expect = 8e-62
 Identities = 134/387 (34%), Positives = 220/387 (56%), Gaps = 22/387 (5%)

Query: 26  NTEFAVDLYQEVSLSH-KDNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQET---- 80
           N EF +D+++E++ ++  DNI FS L +   L MV LGA+G+ ++Q+ + L    T    
Sbjct: 8   NVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHFSHTVDSL 67

Query: 81  -----------SAGEEFFVLKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKE 129
                       AG         FS I++     T ++AN LY  +     +QYL  +++
Sbjct: 68  KPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQYLSCSEK 127

Query: 130 FFQSAIKLVDF-QDAKACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGD 188
           ++Q+ ++ VDF Q  +   + I+ WVE KT+GK+ ++F      P + +VLVNAIYFKG 
Sbjct: 128 WYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVNAIYFKGQ 187

Query: 189 WKQKFRKEDTQLINFTKKNGSTVKIPMMKALLRTKYGYFSESSLNYQVLELSYKGDEFSL 248
           W+ KF+  +T    F    G  V + MM  +   K  +  E  +  QVLEL Y  ++ S+
Sbjct: 188 WQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQM--QVLELPYVNNKLSM 245

Query: 249 IIILPAEGMDIEEVEKLITAQQILKWLSE--MQEEEVEISLPRFKVEQKVDFKDVLYSLN 306
           II+LP    +++++EK + +    +W S   M E EVE+ LPRFK+E K +   +L SL 
Sbjct: 246 IILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSLLKSLG 305

Query: 307 ITEIFSG-GCDLSGITDSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSLAQSQF 365
           +T++F+    DLSG++ +  +Y+S+   K + +++E+G+EAA +TG  I V     ++QF
Sbjct: 306 VTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLPMRAQF 365

Query: 366 IANHPFLFIMKHNPTESILFMGRVTNP 392
            ANHPFLF ++H  T +ILF G++ +P
Sbjct: 366 KANHPFLFFIRHTHTNTILFCGKLASP 392


>gi|41152086 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 6 [Homo sapiens]
          Length = 376

 Score =  229 bits (585), Expect = 3e-60
 Identities = 131/375 (34%), Positives = 218/375 (58%), Gaps = 8/375 (2%)

Query: 23  AQKNTEFAVDLYQEVSLSHKDNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSA 82
           A+ N  FA++L + +   +  N+ FSP+ ++  L MV +GAKG    Q+ Q L   ++  
Sbjct: 5   AEANGTFALNLLKTLGKDNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKSGG 64

Query: 83  GEEFFV-LKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDFQ 141
           G +     +S  + +++   ++   +AN L+ ++       +    ++F+Q+ ++ +DF 
Sbjct: 65  GGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFI 124

Query: 142 DA-KACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQL 200
            A +   + I+TWV  KT+GKI ++ S     PLTRLVLVNA+YF+G+W ++F KE+T+ 
Sbjct: 125 SAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEE 184

Query: 201 INFTKKNGSTVKIPMMKALLRTKYGYFSESSLNYQVLELSYKGDEFSLIIILPAEGMDIE 260
             F         + MM      K  Y  E  +  Q+L L Y G E ++II+LP E  D+ 
Sbjct: 185 RLFKVSKNEEKPVQMMFKQSTFKKTYIGE--IFTQILVLPYVGKELNMIIMLPDETTDLR 242

Query: 261 EVEKLITAQQILKW--LSEMQEEEVEISLPRFKVEQKVDFKDVLYSLNITEIFS-GGCDL 317
            VEK +T ++ ++W  L  M EEEVE+SLPRFK+E+  D + VL +L +T+ F  G  D 
Sbjct: 243 TVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADF 302

Query: 318 SGITDSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSLAQSQFIANHPFLFIMKH 377
           SG++  +++ +S+V  K F E+NE+G+EAA +T   + +  +    +F A+HPFLF ++H
Sbjct: 303 SGMS-QTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFFIQH 361

Query: 378 NPTESILFMGRVTNP 392
           + T  ILF GR ++P
Sbjct: 362 SKTNGILFCGRFSSP 376


>gi|17998551 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 12 [Homo sapiens]
          Length = 405

 Score =  228 bits (582), Expect = 6e-60
 Identities = 137/400 (34%), Positives = 220/400 (55%), Gaps = 35/400 (8%)

Query: 26  NTEFAVDLYQEVSLSHKD-NIIFSPLGITLVLEMVQLGAKGKAQQQIRQTL--------- 75
           NT+F  DL+QE+    +  NI FSPL ++  L MV+LGA+  +  QI + L         
Sbjct: 8   NTKFCFDLFQEIGKDDRHKNIFFSPLSLSAALGMVRLGARSDSAHQIDEVLHFNEFSQNE 67

Query: 76  -----------KQQETSAGEEFFVLKSFFSAISEK----KQEFTFNLANALYLQEGFTVK 120
                      KQ+  S   E  ++  +F  +  K    K ++T ++AN LY ++ F + 
Sbjct: 68  SKEPDPCLKSNKQKAGSLNNESGLVSCYFGQLLSKLDRIKTDYTLSIANRLYGEQEFPIC 127

Query: 121 EQYLHGNKEFFQSAIKLVDFQ-DAKACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVL 179
           ++YL G  +F+ + I+ VDFQ + +   + I+ WVE ++ GKIK++FS +     T LVL
Sbjct: 128 QEYLDGVIQFYHTTIESVDFQKNPEKSRQEINFWVECQSQGKIKELFSKDAINAETVLVL 187

Query: 180 VNAIYFKGDWKQKFRKEDTQLINFTKKNGSTVKIPMMKALLRTKYGYFSESSLNYQVLEL 239
           VNA+YFK  W+  F  E+T    F         + MM      + G+  E  +  Q+LE+
Sbjct: 188 VNAVYFKAKWETYFDHENTVDAPFCLNANENKSVKMMTQKGLYRIGFIEE--VKAQILEM 245

Query: 240 SYKGDEFSLIIILPAEGMD----IEEVEKLITAQQILKWLSE--MQEEEVEISLPRFKVE 293
            Y   + S+ ++LP+   D    +EE+E+ IT ++++ W S   M EE V +S PRF +E
Sbjct: 246 RYTKGKLSMFVLLPSHSKDNLKGLEELERKITYEKMVAWSSSENMSEESVVLSFPRFTLE 305

Query: 294 QKVDFKDVLYSLNITEIFSGG-CDLSGITDSSEVYVSQVTQKVFFEINEDGSEAATSTGI 352
              D   +L  + IT+IF     DL+GI+ S  +Y+S++  K F E++E+G++AA +TG 
Sbjct: 306 DSYDLNSILQDMGITDIFDETRADLTGISPSPNLYLSKIIHKTFVEVDENGTQAAAATGA 365

Query: 353 HIPVIMSLAQSQFIANHPFLFIMKHNPTESILFMGRVTNP 392
            +      +  +F ANHPFLF ++HN T++ILF GRV +P
Sbjct: 366 VVSERSLRSWVEFNANHPFLFFIRHNKTQTILFYGRVCSP 405


>gi|13489087 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 1 [Homo sapiens]
          Length = 379

 Score =  219 bits (557), Expect = 5e-57
 Identities = 132/378 (34%), Positives = 217/378 (57%), Gaps = 17/378 (4%)

Query: 26  NTEFAVDLYQEVSLSHK-DNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSAGE 84
           NT FA+DL+  +S ++   NI  SP  I+  + MV LG +G    Q+ +T          
Sbjct: 8   NTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHFNTVEEVH 67

Query: 85  EFFVLKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDFQDAK 144
             F  +S  + I+++   +   LAN LY ++ +    ++L   ++ + + +  VDFQ A 
Sbjct: 68  SRF--QSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVDFQHAS 125

Query: 145 ACA-EMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQLINF 203
             A + I+ WV+ +T+GKI ++ +      +T+LVLVNAIYFKG+WK KF KE T    F
Sbjct: 126 EDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEATTNAPF 185

Query: 204 --TKKNGSTVKIPMMKALLRTKYGYFSESSLNYQVLELSYKGDEFSLIIILPA----EGM 257
              KK+  TVK  MM    +  YGY  +  L  +VLEL Y+G+E S++I+LP     E  
Sbjct: 186 RLNKKDRKTVK--MMYQKKKFAYGYIED--LKCRVLELPYQGEELSMVILLPDDIEDEST 241

Query: 258 DIEEVEKLITAQQILKWLSEMQEE--EVEISLPRFKVEQKVDFKDVLYSLNITEIF-SGG 314
            ++++E+ +T +++ +W      +  EV +SLPRFK+E+       L  L + ++F S  
Sbjct: 242 GLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSSK 301

Query: 315 CDLSGITDSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSLAQSQFIANHPFLFI 374
            DLSG++ + ++++S++  K F E+NE+G+EAA +T       M + +  F A+HPFLF 
Sbjct: 302 ADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTADHPFLFF 361

Query: 375 MKHNPTESILFMGRVTNP 392
           ++HN + SILF+GR ++P
Sbjct: 362 IRHNSSGSILFLGRFSSP 379


>gi|211904156 plasminogen activator inhibitor type 1, member 2
           isoform c precursor [Homo sapiens]
          Length = 409

 Score =  214 bits (544), Expect = 1e-55
 Identities = 122/354 (34%), Positives = 204/354 (57%), Gaps = 9/354 (2%)

Query: 43  DNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSAGEEFFVLKSFFSAISEKKQE 102
           DNI+ SP GI  VL M+QLGA G+ ++Q+   ++      G+   +LK    AI  KK +
Sbjct: 61  DNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGK---ILKKINKAIVSKKNK 117

Query: 103 FTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDFQDAKACAEMISTWVERKTDGKI 162
               +ANA++++    ++  ++  NK+ FQ  ++ V+F+D  +  + I+ WV+ +T   I
Sbjct: 118 DIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMI 177

Query: 163 KDMFSGEEF-GPLTRLVLVNAIYFKGDWKQKFRKEDTQLINFTKKNGSTVKIPMMKALLR 221
            ++ S +   G LTRLVLVNA+YFKG WK +F+ E+T+   F   +G + ++PM+  L  
Sbjct: 178 DNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSV 237

Query: 222 TKYGYFS-ESSLNYQVLELSYKGDEFSLIIILPAE-GMDIEEVEKLITAQQILKWLSEMQ 279
            + G  S  + L Y  +EL Y G+  S++I LP E    +  +   I+ + I  W+S M 
Sbjct: 238 FRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMV 297

Query: 280 EEEVEISLPRFKVEQKVDFKDVLYSLNITEIF-SGGCDLSGITDSSEVYVSQVTQKVFFE 338
            + V++ LP+F    + D K+ L  L IT++F S   + + IT S  ++VS + QK   E
Sbjct: 298 PKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIE 357

Query: 339 INEDGSEAATSTGIHIPVIMSLAQSQFIANHPFLFIMKHNPTESILFMGRVTNP 392
           ++EDG++A+ +T   +  I   +   FI + PFLF ++HNPT ++LFMG++  P
Sbjct: 358 VSEDGTKASAATTAIL--IARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 409


>gi|211904154 plasminogen activator inhibitor type 1, member 2
           isoform b precursor [Homo sapiens]
          Length = 397

 Score =  214 bits (544), Expect = 1e-55
 Identities = 122/354 (34%), Positives = 204/354 (57%), Gaps = 9/354 (2%)

Query: 43  DNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSAGEEFFVLKSFFSAISEKKQE 102
           DNI+ SP GI  VL M+QLGA G+ ++Q+   ++      G+   +LK    AI  KK +
Sbjct: 49  DNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGK---ILKKINKAIVSKKNK 105

Query: 103 FTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDFQDAKACAEMISTWVERKTDGKI 162
               +ANA++++    ++  ++  NK+ FQ  ++ V+F+D  +  + I+ WV+ +T   I
Sbjct: 106 DIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMI 165

Query: 163 KDMFSGEEF-GPLTRLVLVNAIYFKGDWKQKFRKEDTQLINFTKKNGSTVKIPMMKALLR 221
            ++ S +   G LTRLVLVNA+YFKG WK +F+ E+T+   F   +G + ++PM+  L  
Sbjct: 166 DNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSV 225

Query: 222 TKYGYFS-ESSLNYQVLELSYKGDEFSLIIILPAE-GMDIEEVEKLITAQQILKWLSEMQ 279
            + G  S  + L Y  +EL Y G+  S++I LP E    +  +   I+ + I  W+S M 
Sbjct: 226 FRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMV 285

Query: 280 EEEVEISLPRFKVEQKVDFKDVLYSLNITEIF-SGGCDLSGITDSSEVYVSQVTQKVFFE 338
            + V++ LP+F    + D K+ L  L IT++F S   + + IT S  ++VS + QK   E
Sbjct: 286 PKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIE 345

Query: 339 INEDGSEAATSTGIHIPVIMSLAQSQFIANHPFLFIMKHNPTESILFMGRVTNP 392
           ++EDG++A+ +T   +  I   +   FI + PFLF ++HNPT ++LFMG++  P
Sbjct: 346 VSEDGTKASAATTAIL--IARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 397


>gi|211904152 plasminogen activator inhibitor type 1, member 2
           isoform b precursor [Homo sapiens]
          Length = 397

 Score =  214 bits (544), Expect = 1e-55
 Identities = 122/354 (34%), Positives = 204/354 (57%), Gaps = 9/354 (2%)

Query: 43  DNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSAGEEFFVLKSFFSAISEKKQE 102
           DNI+ SP GI  VL M+QLGA G+ ++Q+   ++      G+   +LK    AI  KK +
Sbjct: 49  DNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGK---ILKKINKAIVSKKNK 105

Query: 103 FTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDFQDAKACAEMISTWVERKTDGKI 162
               +ANA++++    ++  ++  NK+ FQ  ++ V+F+D  +  + I+ WV+ +T   I
Sbjct: 106 DIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMI 165

Query: 163 KDMFSGEEF-GPLTRLVLVNAIYFKGDWKQKFRKEDTQLINFTKKNGSTVKIPMMKALLR 221
            ++ S +   G LTRLVLVNA+YFKG WK +F+ E+T+   F   +G + ++PM+  L  
Sbjct: 166 DNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSV 225

Query: 222 TKYGYFS-ESSLNYQVLELSYKGDEFSLIIILPAE-GMDIEEVEKLITAQQILKWLSEMQ 279
            + G  S  + L Y  +EL Y G+  S++I LP E    +  +   I+ + I  W+S M 
Sbjct: 226 FRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMV 285

Query: 280 EEEVEISLPRFKVEQKVDFKDVLYSLNITEIF-SGGCDLSGITDSSEVYVSQVTQKVFFE 338
            + V++ LP+F    + D K+ L  L IT++F S   + + IT S  ++VS + QK   E
Sbjct: 286 PKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIE 345

Query: 339 INEDGSEAATSTGIHIPVIMSLAQSQFIANHPFLFIMKHNPTESILFMGRVTNP 392
           ++EDG++A+ +T   +  I   +   FI + PFLF ++HNPT ++LFMG++  P
Sbjct: 346 VSEDGTKASAATTAIL--IARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 397


>gi|24307907 plasminogen activator inhibitor type 1, member 2
           isoform a precursor [Homo sapiens]
          Length = 398

 Score =  211 bits (538), Expect = 7e-55
 Identities = 123/355 (34%), Positives = 205/355 (57%), Gaps = 10/355 (2%)

Query: 43  DNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSAGEEFFVLKSFFSAISEKKQE 102
           DNI+ SP GI  VL M+QLGA G+ ++Q+   ++      G+   +LK    AI  KK +
Sbjct: 49  DNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGK---ILKKINKAIVSKKNK 105

Query: 103 FTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDFQDAKACAEMISTWVERKTDGKI 162
               +ANA++++    ++  ++  NK+ FQ  ++ V+F+D  +  + I+ WV+ +T   I
Sbjct: 106 DIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMI 165

Query: 163 KDMFSGEEF-GPLTRLVLVNAIYFKGDWKQKFRKEDTQLINFTKKNGSTVKIPMMKALLR 221
            ++ S +   G LTRLVLVNA+YFKG WK +F+ E+T+   F   +G + ++PM+  L  
Sbjct: 166 DNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSV 225

Query: 222 TKYGYFS-ESSLNYQVLELSYKGDEFSLIIILPAE-GMDIEEVEKLITAQQILKWLSEMQ 279
            + G  S  + L Y  +EL Y G+  S++I LP E    +  +   I+ + I  W+S M 
Sbjct: 226 FRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMV 285

Query: 280 EEEVEISLPRFKVEQKVDFKDVLYSLNITEIF-SGGCDLSGITDSSE-VYVSQVTQKVFF 337
            + V++ LP+F    + D K+ L  L IT++F S   + + IT  SE ++VS + QK   
Sbjct: 286 PKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKI 345

Query: 338 EINEDGSEAATSTGIHIPVIMSLAQSQFIANHPFLFIMKHNPTESILFMGRVTNP 392
           E++EDG++A+ +T   +  I   +   FI + PFLF ++HNPT ++LFMG++  P
Sbjct: 346 EVSEDGTKASAATTAIL--IARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 398


>gi|8393956 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 13 [Homo sapiens]
          Length = 391

 Score =  207 bits (528), Expect = 1e-53
 Identities = 118/386 (30%), Positives = 214/386 (55%), Gaps = 21/386 (5%)

Query: 26  NTEFAVDLYQEVSLSHKDNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTL-KQQETSAG- 83
           +T    DL++E+  ++  NI FSP+GI   + MV LG +G    Q+ +    ++ET +  
Sbjct: 8   STRLGFDLFKELKKTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKETKSSR 67

Query: 84  ---EEFFVLKS----------FFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKEF 130
              EE  V+++          F + IS+   ++  N+ N L+ ++ +   ++YL   +++
Sbjct: 68  IKAEEKEVIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKYLDYVEKY 127

Query: 131 FQSAIKLVDFQDAK-ACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDW 189
           + ++++ VDF +A     + I++WVE KT+ KIKD+F        T+LVLVN +YFKG W
Sbjct: 128 YHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMVYFKGQW 187

Query: 190 KQKFRKEDTQLINFTKKNGSTVKIPMMKALLRTKYGYFSESSLNYQVLELSYKGDEFSLI 249
            ++F+KE+T+   F     ++  + MM       + +  +  L  ++L + YK ++ S+ 
Sbjct: 188 DREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLED--LQAKILGIPYKNNDLSMF 245

Query: 250 IILPAEGMDIEEVEKLITAQQILKWLS--EMQEEEVEISLPRFKVEQKVDFKDVLYSLNI 307
           ++LP +   +E++   I+ +++++W S   M+E +V + LPRF+VE   D + VL ++ +
Sbjct: 246 VLLPNDIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAVLAAMGM 305

Query: 308 TEIFSGG-CDLSGITDSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSLAQSQFI 366
            + FS    D SG++  S +Y  +     F  + E+G+EAA +TGI   V  +       
Sbjct: 306 GDAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAPGHENVH 365

Query: 367 ANHPFLFIMKHNPTESILFMGRVTNP 392
            NHPFLF ++HN + SILF GR ++P
Sbjct: 366 CNHPFLFFIRHNESNSILFFGRFSSP 391


>gi|10835159 plasminogen activator inhibitor-1 [Homo sapiens]
          Length = 402

 Score =  206 bits (524), Expect = 3e-53
 Identities = 121/370 (32%), Positives = 201/370 (54%), Gaps = 7/370 (1%)

Query: 27  TEFAVDLYQEVSLSHKD-NIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSAGEE 85
           ++F V ++Q+V+ + KD N++FSP G+  VL M+QL   G+ QQQI+  +  +    G  
Sbjct: 36  SDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMA 95

Query: 86  FFVLKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDFQDAKA 145
              L+  +  +     +   +  +A+++Q    + + ++      F+S +K VDF + + 
Sbjct: 96  P-ALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVER 154

Query: 146 CAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQLINFTK 205
              +I+ WV+  T G I ++        LTRLVLVNA+YF G WK  F    T    F K
Sbjct: 155 ARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHK 214

Query: 206 KNGSTVKIPMMKALLRTKYGYFSESSLN-YQVLELSYKGDEFSLIIILPAE-GMDIEEVE 263
            +GSTV +PMM    +  Y  F+    + Y +LEL Y GD  S+ I  P E  + +  + 
Sbjct: 215 SDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALT 274

Query: 264 KLITAQQILKWLSEMQEEEVEISLPRFKVEQKVDFKDVLYSLNITEIF-SGGCDLSGITD 322
            +++AQ I  W   M      + LP+F +E +VD +  L +L +T++F     D + ++D
Sbjct: 275 NILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSD 334

Query: 323 SSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSLAQSQFIANHPFLFIMKHNPTES 382
              ++V+Q  QKV  E+NE G+ A++ST + +   M  A  + I + PFLF+++HNPT +
Sbjct: 335 QEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARM--APEEIIMDRPFLFVVRHNPTGT 392

Query: 383 ILFMGRVTNP 392
           +LFMG+V  P
Sbjct: 393 VLFMGQVMEP 402


>gi|38504669 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 8 isoform a [Homo sapiens]
          Length = 374

 Score =  206 bits (523), Expect = 4e-53
 Identities = 123/374 (32%), Positives = 207/374 (55%), Gaps = 10/374 (2%)

Query: 24  QKNTEFAVDLYQEVSLSHKD-NIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSA 82
           + N  FA+ L++ +       N+ FSP+ I+  L MV +GAKG    Q+ Q L   +   
Sbjct: 6   EANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYKD-- 63

Query: 83  GEEFFVLKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDF-Q 141
           G+     +S  S ++    ++    AN L+ ++       +    ++F+Q+ ++ + F +
Sbjct: 64  GDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAE 123

Query: 142 DAKACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQLI 201
           D + C + I+ WV  KT+GKI ++       PLT+LVLVNAIYFKG W ++F ++ T+ +
Sbjct: 124 DTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGM 183

Query: 202 NFTKKNGSTVKIPMMKALLRTKYGYFSESSLNYQVLELSYKGDEFSLIIILPAEGMDIEE 261
            F K N     + MM    + K GY  E  ++ QVLEL Y  +E S++I+LP +  D+  
Sbjct: 184 LF-KTNEEKKTVQMMFKEAKFKMGYADE--VHTQVLELPYVEEELSMVILLPDDNTDLAV 240

Query: 262 VEKLITAQQILKWLS--EMQEEEVEISLPRFKVEQKVDFKDVLYSLNITEIFSGG-CDLS 318
           VEK +T ++   W +  ++ + +V++ LPR K+E+  D +  L  L + + F     D S
Sbjct: 241 VEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFS 300

Query: 319 GITDSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSLAQSQFIANHPFLFIMKHN 378
           G++    V +S+V  K F E+NE+G+EAA +T +      S  + +F A+HPFLF ++H+
Sbjct: 301 GMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHH 360

Query: 379 PTESILFMGRVTNP 392
            T  ILF GR ++P
Sbjct: 361 KTNCILFCGRFSSP 374


>gi|38504673 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 8 isoform a [Homo sapiens]
          Length = 374

 Score =  206 bits (523), Expect = 4e-53
 Identities = 123/374 (32%), Positives = 207/374 (55%), Gaps = 10/374 (2%)

Query: 24  QKNTEFAVDLYQEVSLSHKD-NIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSA 82
           + N  FA+ L++ +       N+ FSP+ I+  L MV +GAKG    Q+ Q L   +   
Sbjct: 6   EANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYKD-- 63

Query: 83  GEEFFVLKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDF-Q 141
           G+     +S  S ++    ++    AN L+ ++       +    ++F+Q+ ++ + F +
Sbjct: 64  GDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAE 123

Query: 142 DAKACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQLI 201
           D + C + I+ WV  KT+GKI ++       PLT+LVLVNAIYFKG W ++F ++ T+ +
Sbjct: 124 DTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGM 183

Query: 202 NFTKKNGSTVKIPMMKALLRTKYGYFSESSLNYQVLELSYKGDEFSLIIILPAEGMDIEE 261
            F K N     + MM    + K GY  E  ++ QVLEL Y  +E S++I+LP +  D+  
Sbjct: 184 LF-KTNEEKKTVQMMFKEAKFKMGYADE--VHTQVLELPYVEEELSMVILLPDDNTDLAV 240

Query: 262 VEKLITAQQILKWLS--EMQEEEVEISLPRFKVEQKVDFKDVLYSLNITEIFSGG-CDLS 318
           VEK +T ++   W +  ++ + +V++ LPR K+E+  D +  L  L + + F     D S
Sbjct: 241 VEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFS 300

Query: 319 GITDSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSLAQSQFIANHPFLFIMKHN 378
           G++    V +S+V  K F E+NE+G+EAA +T +      S  + +F A+HPFLF ++H+
Sbjct: 301 GMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHH 360

Query: 379 PTESILFMGRVTNP 392
            T  ILF GR ++P
Sbjct: 361 KTNCILFCGRFSSP 374


>gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo
           sapiens]
          Length = 464

 Score =  205 bits (521), Expect = 7e-53
 Identities = 129/381 (33%), Positives = 202/381 (53%), Gaps = 14/381 (3%)

Query: 23  AQKNTEFAVDLYQEV--SLSHKDNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLK---- 76
           ++ N+ FA   YQ +  S +  DNI  SPL I+    M +LGA     QQ+ +  K    
Sbjct: 84  SKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTI 143

Query: 77  QQETSAGEEFFVLKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIK 136
            ++TS    FF  K       +  +      AN L+  +  T  E Y   ++  + + ++
Sbjct: 144 SEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQDISELVYGAKLQ 203

Query: 137 LVDFQD-AKACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRK 195
            +DF++ A+     I+ WV  KT+G+I D+   E    LT LVLVN IYFKG WK KF  
Sbjct: 204 PLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKGLWKSKFSP 263

Query: 196 EDTQLINFTKKNGSTVKIPMMKALLRTKYGYFSESSLNYQVLELSYKGDEFSLIIILPAE 255
           E+T+   F K +G +    MM    + +Y   +E +   QVLEL +KGD+ ++++ILP  
Sbjct: 264 ENTRKELFYKADGESCSASMMYQEGKFRYRRVAEGT---QVLELPFKGDDITMVLILPKP 320

Query: 256 GMDIEEVEKLITAQQILKWLSEMQEEEVEISLPRFKVEQKVDFKDVLYSLNITEIFS-GG 314
              + +VEK +T + + +WL E++E  + + +PRF++E     K+ L  + + ++FS   
Sbjct: 321 EKSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEK 380

Query: 315 CDLSGIT--DSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIP-VIMSLAQSQFIANHPF 371
             L GI      ++YVS    K F E+NE+GSEAA ST + I    ++  +  F AN PF
Sbjct: 381 SKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRPF 440

Query: 372 LFIMKHNPTESILFMGRVTNP 392
           L  ++  P  +I+FMGRV NP
Sbjct: 441 LVFIREVPLNTIIFMGRVANP 461


>gi|4826902 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 10 [Homo sapiens]
          Length = 397

 Score =  204 bits (519), Expect = 1e-52
 Identities = 127/390 (32%), Positives = 212/390 (54%), Gaps = 27/390 (6%)

Query: 28  EFAVDLYQEVSLSHKD-NIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLK---------- 76
           +FA++L ++++ S +  NI FS   I+  L +V LGAKG    Q+ Q L+          
Sbjct: 10  QFALELSKKLAESAQGKNIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQFNRDQGVKCD 69

Query: 77  -QQETSAGEEFFVLKS---------FFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHG 126
            + E     EF +  S           S I +   ++    ANA+Y ++ +    +YL  
Sbjct: 70  PESEKKRKMEFNLSNSEEIHSDFQTLISEILKPNDDYLLKTANAIYGEKTYAFHNKYLED 129

Query: 127 NKEFFQSAIKLVDFQDAK-ACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYF 185
            K +F +  + V+F +A     + I++WVER+T+GKI+++   +     TR++LVNA+YF
Sbjct: 130 MKTYFGAEPQPVNFVEASDQIRKDINSWVERQTEGKIQNLLPDDSVDSTTRMILVNALYF 189

Query: 186 KGDWKQKFRKEDTQLINFTKKNGSTVKIPMMKALLRTKYGYFSESSLNYQVLELSYKGDE 245
           KG W+ +F  ++T    F  +   T   P+    ++ K   F         L+L YK  +
Sbjct: 190 KGIWEHQFLVQNTTEKPF--RINETTSKPVQMMFMKKKLHIFHIEKPKAVGLQLYYKSRD 247

Query: 246 FSLIIILPAEGMDIEEVEKLITAQQILKWLSE--MQEEEVEISLPRFKVEQKVDFKDVLY 303
            SL+I+LP +   +E++EK IT +++ +W S   M+  EV++ LP+FK+E   D K  L 
Sbjct: 248 LSLLILLPEDINGLEQLEKAITYEKLNEWTSADMMELYEVQLHLPKFKLEDSYDLKSTLS 307

Query: 304 SLNITEIFSGG-CDLSGITDSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSLAQ 362
           S+ +++ FS    D SG++ +  +++S V  K F EINE G+EAA  +G  I + + +  
Sbjct: 308 SMGMSDAFSQSKADFSGMSSARNLFLSNVFHKAFVEINEQGTEAAAGSGSEIDIRIRVPS 367

Query: 363 SQFIANHPFLFIMKHNPTESILFMGRVTNP 392
            +F ANHPFLF ++HN T +ILF GR+ +P
Sbjct: 368 IEFNANHPFLFFIRHNKTNTILFYGRLCSP 397


>gi|50659080 serpin peptidase inhibitor, clade A, member 3 precursor
           [Homo sapiens]
          Length = 423

 Score =  202 bits (515), Expect = 3e-52
 Identities = 121/376 (32%), Positives = 202/376 (53%), Gaps = 11/376 (2%)

Query: 23  AQKNTEFAVDLYQEVSLSHKD-NIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQ--E 79
           A  N +FA  LY+++ L   D N+IFSPL I+  L  + LGA      +I + LK    E
Sbjct: 50  ASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTE 109

Query: 80  TSAGEEFFVLKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVD 139
           TS  E     +     +++   E   ++ NA++++E  ++ +++    K  + S     D
Sbjct: 110 TSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATD 169

Query: 140 FQDAKACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQ 199
           FQD+ A  ++I+ +V+  T GKI D+   ++    T +VLVN I+FK  W+  F  +DT 
Sbjct: 170 FQDSAAAKKLINDYVKNGTRGKITDLI--KDLDSQTMMVLVNYIFFKAKWEMPFDPQDTH 227

Query: 200 LINFTKKNGSTVKIPMMKALLRTKYGYFSESSLNYQVLELSYKGDEFSLIIILPAEGMDI 259
              F       V +PMM +L      YF +  L+  V+EL Y G+  +L I+   + M  
Sbjct: 228 QSRFYLSKKKWVMVPMM-SLHHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKM-- 284

Query: 260 EEVEKLITAQQILKWLSEMQEEEV-EISLPRFKVEQKVDFKDVLYSLNITEIFSGGCDLS 318
           EEVE ++  + + +W   ++  E+ E+ LP+F + +  +  D+L  L I E F+   DLS
Sbjct: 285 EEVEAMLLPETLKRWRDSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLS 344

Query: 319 GITDSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSLAQSQFIA--NHPFLFIMK 376
           GIT +  + VSQV  K   ++ E+G+EA+ +T + I ++ +L +++ I   N PFL I+ 
Sbjct: 345 GITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIV 404

Query: 377 HNPTESILFMGRVTNP 392
              T++I FM +VTNP
Sbjct: 405 PTDTQNIFFMSKVTNP 420


>gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo
           sapiens]
          Length = 376

 Score =  193 bits (491), Expect = 2e-49
 Identities = 115/354 (32%), Positives = 190/354 (53%), Gaps = 9/354 (2%)

Query: 44  NIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSAGEEFFVLKSFFSAISEKKQEF 103
           N+  SP+ I+  L MV LGAKG    Q+ Q L           F  +S  + +++   ++
Sbjct: 27  NVFCSPVSISSALAMVLLGAKGNTATQMAQALSLNTEEDIHRAF--QSLLTEVNKAGTQY 84

Query: 104 TFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDF-QDAKACAEMISTWVERKTDGKI 162
               AN L+ ++       +     +F+ + +K + F + A+   + I+TWV +KT+GKI
Sbjct: 85  LLRTANRLFGEKTCQFLSTFKESCLQFYHAELKELSFIRAAEESRKHINTWVSKKTEGKI 144

Query: 163 KDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQLINFTKKNGSTVKIPMMKALLRT 222
           +++  G      TRLVLVNAIYFKG W + F +  T+ + F         + MM      
Sbjct: 145 EELLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYTREMPFKINQEEQRPVQMMYQEATF 204

Query: 223 KYGYFSESSLNYQVLELSYKGDEFSLIIILPAEGMDIEEVEKLITAQQILKWLSE--MQE 280
           K  +  E  +  Q+LEL Y   E SL+++LP +G+++  VEK +T +++  W     M+ 
Sbjct: 205 KLAHVGE--VRAQLLELPYARKELSLLVLLPDDGVELSTVEKSLTFEKLTAWTKPDCMKS 262

Query: 281 EEVEISLPRFKVEQKVDFKDVLYSLNITEIF-SGGCDLSGITDSSEVYVSQVTQKVFFEI 339
            EVE+ LP+FK+++  D + VL  L I + F  G  DLS ++   ++ +S+   K F E+
Sbjct: 263 TEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQGKADLSAMSAERDLCLSKFVHKSFVEV 322

Query: 340 NEDGSEAATSTGIHIPVIMSLAQS-QFIANHPFLFIMKHNPTESILFMGRVTNP 392
           NE+G+EAA ++   +     +    +F A+HPFLF ++HN   SILF GR ++P
Sbjct: 323 NEEGTEAAAASSCFVVAECCMESGPRFCADHPFLFFIRHNRANSILFCGRFSSP 376


>gi|219689110 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 2 [Homo sapiens]
          Length = 415

 Score =  189 bits (480), Expect = 4e-48
 Identities = 122/411 (29%), Positives = 213/411 (51%), Gaps = 47/411 (11%)

Query: 26  NTEFAVDLYQEVS-LSHKDNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSAGE 84
           NT FA++L++ ++  S   N+  SP  I+  + MV +G++G  + Q+ + L+  E  A  
Sbjct: 8   NTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANA 67

Query: 85  ------EFFV-----------------------------LKSFFSAISEKKQEFTFNLAN 109
                 E F                               +S  SAI+     +     N
Sbjct: 68  VTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVN 127

Query: 110 ALYLQEGFTVKEQYLHGNKEFFQSAIKLVDFQD-AKACAEMISTWVERKTDGKIKDMFSG 168
            L+ ++  + +E+Y+   ++++ S  + VDF + A+   + I++WV+ +T GKI ++   
Sbjct: 128 KLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPE 187

Query: 169 EEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQLINFTKKNGSTVKIPMMKALLRTKYGYFS 228
                 TR+VLVNA+YFKG WK  F K+   L  F   +     + MM    +   GY  
Sbjct: 188 GSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIE 247

Query: 229 ESSLNYQVLELSYKGDEFSLIIILPAEGMDI----EEVEKLITAQQILKWLS--EMQEEE 282
           +  L  Q+LEL Y GD  S+ ++LP E  D+    E +E  IT  ++ KW S  +M E+E
Sbjct: 248 D--LKAQILELPYAGD-VSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDE 304

Query: 283 VEISLPRFKVEQKVDFKDVLYSLNITEIFS-GGCDLSGITDSSEVYVSQVTQKVFFEINE 341
           VE+ +P+FK+E+  + + +L S+ + + F+ G  + SG+++ +++++S+V  +   ++NE
Sbjct: 305 VEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNE 364

Query: 342 DGSEAATSTGIHIPVIMSLAQSQFIANHPFLFIMKHNPTESILFMGRVTNP 392
           +G+EAA  TG  +         QF+A+HPFLF++ H  T  ILF GR ++P
Sbjct: 365 EGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415


>gi|4505595 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 2 [Homo sapiens]
          Length = 415

 Score =  189 bits (480), Expect = 4e-48
 Identities = 122/411 (29%), Positives = 213/411 (51%), Gaps = 47/411 (11%)

Query: 26  NTEFAVDLYQEVS-LSHKDNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSAGE 84
           NT FA++L++ ++  S   N+  SP  I+  + MV +G++G  + Q+ + L+  E  A  
Sbjct: 8   NTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANA 67

Query: 85  ------EFFV-----------------------------LKSFFSAISEKKQEFTFNLAN 109
                 E F                               +S  SAI+     +     N
Sbjct: 68  VTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVN 127

Query: 110 ALYLQEGFTVKEQYLHGNKEFFQSAIKLVDFQD-AKACAEMISTWVERKTDGKIKDMFSG 168
            L+ ++  + +E+Y+   ++++ S  + VDF + A+   + I++WV+ +T GKI ++   
Sbjct: 128 KLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPE 187

Query: 169 EEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQLINFTKKNGSTVKIPMMKALLRTKYGYFS 228
                 TR+VLVNA+YFKG WK  F K+   L  F   +     + MM    +   GY  
Sbjct: 188 GSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIE 247

Query: 229 ESSLNYQVLELSYKGDEFSLIIILPAEGMDI----EEVEKLITAQQILKWLS--EMQEEE 282
           +  L  Q+LEL Y GD  S+ ++LP E  D+    E +E  IT  ++ KW S  +M E+E
Sbjct: 248 D--LKAQILELPYAGD-VSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDE 304

Query: 283 VEISLPRFKVEQKVDFKDVLYSLNITEIFS-GGCDLSGITDSSEVYVSQVTQKVFFEINE 341
           VE+ +P+FK+E+  + + +L S+ + + F+ G  + SG+++ +++++S+V  +   ++NE
Sbjct: 305 VEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNE 364

Query: 342 DGSEAATSTGIHIPVIMSLAQSQFIANHPFLFIMKHNPTESILFMGRVTNP 392
           +G+EAA  TG  +         QF+A+HPFLF++ H  T  ILF GR ++P
Sbjct: 365 EGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415


>gi|73858564 corticosteroid binding globulin precursor [Homo
           sapiens]
          Length = 405

 Score =  178 bits (452), Expect = 7e-45
 Identities = 121/383 (31%), Positives = 202/383 (52%), Gaps = 17/383 (4%)

Query: 16  SQASRCSAQKNTEFAVDLYQE-VSLSHKDNIIFSPLGITLVLEMVQLGAKGKAQQQIRQT 74
           S   R  A  N +FA  LY+  V+LS K NI  SP+ I++ L M+ LG  G  + Q+ Q 
Sbjct: 33  SNHHRGLASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQG 92

Query: 75  L-----KQQETSAGEEFFVLKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKE 129
           L     ++ ET   + F  L   F A S+   E T  + NAL+L     + E +    K 
Sbjct: 93  LGFNLTERSETEIHQGFQHLHQLF-AKSDTSLEMT--MGNALFLDGSLELLESFSADIKH 149

Query: 130 FFQSAIKLVDFQDAKACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDW 189
           +++S +  ++FQD    +  I+++V+ KT GKI D+FSG +   +  LVLVN I+FKG W
Sbjct: 150 YYESEVLAMNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAI--LVLVNYIFFKGTW 207

Query: 190 KQKFRKEDTQLINFTKKNGSTVKIPMMKALLRTKYGYFSESSLNYQVLELSYKGDEFSLI 249
            Q F    T+  NF     + VK+PMM  L  +   Y  ++ L  Q+++++Y G+  ++ 
Sbjct: 208 TQPFDLASTREENFYVDETTVVKVPMM--LQSSTISYLHDAELPCQLVQMNYVGNG-TVF 264

Query: 250 IILPAEGMDIEEVEKLITAQQILKWLSEMQEEEVEISLPRFKVEQKVDFKDVLYSLNITE 309
            ILP +G  +  V   ++   I +W + +   +V++ +P+  +    D  DVL  + I +
Sbjct: 265 FILPDKGK-MNTVIAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIAD 323

Query: 310 IFSGGCDLSGITDSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSLAQSQFIANH 369
           +F+   + S IT  +++  S+V  K   ++NE+G + A STG+ + +       +F  N 
Sbjct: 324 LFTNQANFSRITQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLTSKPIILRF--NQ 381

Query: 370 PFLFIMKHNPTESILFMGRVTNP 392
           PF+ ++  + T S LF+ RV NP
Sbjct: 382 PFIIMIFDHFTWSSLFLARVMNP 404


>gi|189163542 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  175 bits (443), Expect = 8e-44
 Identities = 118/371 (31%), Positives = 186/371 (50%), Gaps = 17/371 (4%)

Query: 28  EFAVDLYQEVS-LSHKDNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSAGEEF 86
           EFA  LY++++  S+  NI FSP+ I     M+ LG K     +I + L    T   E  
Sbjct: 56  EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQ 115

Query: 87  FV--LKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDFQDAK 144
                +     +++   +      N L+L EG  + +++L   K+ + S    V+F D +
Sbjct: 116 IHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTE 175

Query: 145 ACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQLINFT 204
              + I+ +VE+ T GKI D+   +E    T   LVN I+FKG W++ F  +DT+  +F 
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLV--KELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFH 233

Query: 205 KKNGSTVKIPMMKALLRTKYGYFSES---SLNYQVLELSYKGDEFSLIIILPAEGMDIEE 261
               +TVK+PMMK L     G F+      L+  VL + Y G+  + I  LP EG  ++ 
Sbjct: 234 VDQVTTVKVPMMKRL-----GMFNIQHCKKLSSWVLLMKYLGNA-TAIFFLPDEGK-LQH 286

Query: 262 VEKLITAQQILKWLSEMQEEEVEISLPRFKVEQKVDFKDVLYSLNITEIFSGGCDLSGIT 321
           +E  +T   I K+L         + LP+  +    D K VL  L IT++FS G DLSG+T
Sbjct: 287 LENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVT 346

Query: 322 DSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSLAQSQFIANHPFLFIMKHNPTE 381
           + + + +S+   K    I+E G+EAA +  + +  I      +   N PF+F+M    T+
Sbjct: 347 EEAPLKLSKAVHKAVLTIDEKGTEAAGA--MFLEAIPMSIPPEVKFNKPFVFLMIEQNTK 404

Query: 382 SILFMGRVTNP 392
           S LFMG+V NP
Sbjct: 405 SPLFMGKVVNP 415


>gi|189163540 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  175 bits (443), Expect = 8e-44
 Identities = 118/371 (31%), Positives = 186/371 (50%), Gaps = 17/371 (4%)

Query: 28  EFAVDLYQEVS-LSHKDNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSAGEEF 86
           EFA  LY++++  S+  NI FSP+ I     M+ LG K     +I + L    T   E  
Sbjct: 56  EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQ 115

Query: 87  FV--LKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDFQDAK 144
                +     +++   +      N L+L EG  + +++L   K+ + S    V+F D +
Sbjct: 116 IHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTE 175

Query: 145 ACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQLINFT 204
              + I+ +VE+ T GKI D+   +E    T   LVN I+FKG W++ F  +DT+  +F 
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLV--KELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFH 233

Query: 205 KKNGSTVKIPMMKALLRTKYGYFSES---SLNYQVLELSYKGDEFSLIIILPAEGMDIEE 261
               +TVK+PMMK L     G F+      L+  VL + Y G+  + I  LP EG  ++ 
Sbjct: 234 VDQVTTVKVPMMKRL-----GMFNIQHCKKLSSWVLLMKYLGNA-TAIFFLPDEGK-LQH 286

Query: 262 VEKLITAQQILKWLSEMQEEEVEISLPRFKVEQKVDFKDVLYSLNITEIFSGGCDLSGIT 321
           +E  +T   I K+L         + LP+  +    D K VL  L IT++FS G DLSG+T
Sbjct: 287 LENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVT 346

Query: 322 DSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSLAQSQFIANHPFLFIMKHNPTE 381
           + + + +S+   K    I+E G+EAA +  + +  I      +   N PF+F+M    T+
Sbjct: 347 EEAPLKLSKAVHKAVLTIDEKGTEAAGA--MFLEAIPMSIPPEVKFNKPFVFLMIEQNTK 404

Query: 382 SILFMGRVTNP 392
           S LFMG+V NP
Sbjct: 405 SPLFMGKVVNP 415


>gi|189163538 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  175 bits (443), Expect = 8e-44
 Identities = 118/371 (31%), Positives = 186/371 (50%), Gaps = 17/371 (4%)

Query: 28  EFAVDLYQEVS-LSHKDNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSAGEEF 86
           EFA  LY++++  S+  NI FSP+ I     M+ LG K     +I + L    T   E  
Sbjct: 56  EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQ 115

Query: 87  FV--LKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDFQDAK 144
                +     +++   +      N L+L EG  + +++L   K+ + S    V+F D +
Sbjct: 116 IHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTE 175

Query: 145 ACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQLINFT 204
              + I+ +VE+ T GKI D+   +E    T   LVN I+FKG W++ F  +DT+  +F 
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLV--KELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFH 233

Query: 205 KKNGSTVKIPMMKALLRTKYGYFSES---SLNYQVLELSYKGDEFSLIIILPAEGMDIEE 261
               +TVK+PMMK L     G F+      L+  VL + Y G+  + I  LP EG  ++ 
Sbjct: 234 VDQVTTVKVPMMKRL-----GMFNIQHCKKLSSWVLLMKYLGNA-TAIFFLPDEGK-LQH 286

Query: 262 VEKLITAQQILKWLSEMQEEEVEISLPRFKVEQKVDFKDVLYSLNITEIFSGGCDLSGIT 321
           +E  +T   I K+L         + LP+  +    D K VL  L IT++FS G DLSG+T
Sbjct: 287 LENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVT 346

Query: 322 DSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSLAQSQFIANHPFLFIMKHNPTE 381
           + + + +S+   K    I+E G+EAA +  + +  I      +   N PF+F+M    T+
Sbjct: 347 EEAPLKLSKAVHKAVLTIDEKGTEAAGA--MFLEAIPMSIPPEVKFNKPFVFLMIEQNTK 404

Query: 382 SILFMGRVTNP 392
           S LFMG+V NP
Sbjct: 405 SPLFMGKVVNP 415


>gi|189163536 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  175 bits (443), Expect = 8e-44
 Identities = 118/371 (31%), Positives = 186/371 (50%), Gaps = 17/371 (4%)

Query: 28  EFAVDLYQEVS-LSHKDNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSAGEEF 86
           EFA  LY++++  S+  NI FSP+ I     M+ LG K     +I + L    T   E  
Sbjct: 56  EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQ 115

Query: 87  FV--LKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDFQDAK 144
                +     +++   +      N L+L EG  + +++L   K+ + S    V+F D +
Sbjct: 116 IHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTE 175

Query: 145 ACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQLINFT 204
              + I+ +VE+ T GKI D+   +E    T   LVN I+FKG W++ F  +DT+  +F 
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLV--KELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFH 233

Query: 205 KKNGSTVKIPMMKALLRTKYGYFSES---SLNYQVLELSYKGDEFSLIIILPAEGMDIEE 261
               +TVK+PMMK L     G F+      L+  VL + Y G+  + I  LP EG  ++ 
Sbjct: 234 VDQVTTVKVPMMKRL-----GMFNIQHCKKLSSWVLLMKYLGNA-TAIFFLPDEGK-LQH 286

Query: 262 VEKLITAQQILKWLSEMQEEEVEISLPRFKVEQKVDFKDVLYSLNITEIFSGGCDLSGIT 321
           +E  +T   I K+L         + LP+  +    D K VL  L IT++FS G DLSG+T
Sbjct: 287 LENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVT 346

Query: 322 DSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSLAQSQFIANHPFLFIMKHNPTE 381
           + + + +S+   K    I+E G+EAA +  + +  I      +   N PF+F+M    T+
Sbjct: 347 EEAPLKLSKAVHKAVLTIDEKGTEAAGA--MFLEAIPMSIPPEVKFNKPFVFLMIEQNTK 404

Query: 382 SILFMGRVTNP 392
           S LFMG+V NP
Sbjct: 405 SPLFMGKVVNP 415


>gi|189163534 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  175 bits (443), Expect = 8e-44
 Identities = 118/371 (31%), Positives = 186/371 (50%), Gaps = 17/371 (4%)

Query: 28  EFAVDLYQEVS-LSHKDNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSAGEEF 86
           EFA  LY++++  S+  NI FSP+ I     M+ LG K     +I + L    T   E  
Sbjct: 56  EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQ 115

Query: 87  FV--LKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDFQDAK 144
                +     +++   +      N L+L EG  + +++L   K+ + S    V+F D +
Sbjct: 116 IHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTE 175

Query: 145 ACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQLINFT 204
              + I+ +VE+ T GKI D+   +E    T   LVN I+FKG W++ F  +DT+  +F 
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLV--KELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFH 233

Query: 205 KKNGSTVKIPMMKALLRTKYGYFSES---SLNYQVLELSYKGDEFSLIIILPAEGMDIEE 261
               +TVK+PMMK L     G F+      L+  VL + Y G+  + I  LP EG  ++ 
Sbjct: 234 VDQVTTVKVPMMKRL-----GMFNIQHCKKLSSWVLLMKYLGNA-TAIFFLPDEGK-LQH 286

Query: 262 VEKLITAQQILKWLSEMQEEEVEISLPRFKVEQKVDFKDVLYSLNITEIFSGGCDLSGIT 321
           +E  +T   I K+L         + LP+  +    D K VL  L IT++FS G DLSG+T
Sbjct: 287 LENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVT 346

Query: 322 DSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSLAQSQFIANHPFLFIMKHNPTE 381
           + + + +S+   K    I+E G+EAA +  + +  I      +   N PF+F+M    T+
Sbjct: 347 EEAPLKLSKAVHKAVLTIDEKGTEAAGA--MFLEAIPMSIPPEVKFNKPFVFLMIEQNTK 404

Query: 382 SILFMGRVTNP 392
           S LFMG+V NP
Sbjct: 405 SPLFMGKVVNP 415


>gi|189163532 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  175 bits (443), Expect = 8e-44
 Identities = 118/371 (31%), Positives = 186/371 (50%), Gaps = 17/371 (4%)

Query: 28  EFAVDLYQEVS-LSHKDNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSAGEEF 86
           EFA  LY++++  S+  NI FSP+ I     M+ LG K     +I + L    T   E  
Sbjct: 56  EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQ 115

Query: 87  FV--LKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDFQDAK 144
                +     +++   +      N L+L EG  + +++L   K+ + S    V+F D +
Sbjct: 116 IHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTE 175

Query: 145 ACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQLINFT 204
              + I+ +VE+ T GKI D+   +E    T   LVN I+FKG W++ F  +DT+  +F 
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLV--KELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFH 233

Query: 205 KKNGSTVKIPMMKALLRTKYGYFSES---SLNYQVLELSYKGDEFSLIIILPAEGMDIEE 261
               +TVK+PMMK L     G F+      L+  VL + Y G+  + I  LP EG  ++ 
Sbjct: 234 VDQVTTVKVPMMKRL-----GMFNIQHCKKLSSWVLLMKYLGNA-TAIFFLPDEGK-LQH 286

Query: 262 VEKLITAQQILKWLSEMQEEEVEISLPRFKVEQKVDFKDVLYSLNITEIFSGGCDLSGIT 321
           +E  +T   I K+L         + LP+  +    D K VL  L IT++FS G DLSG+T
Sbjct: 287 LENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVT 346

Query: 322 DSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSLAQSQFIANHPFLFIMKHNPTE 381
           + + + +S+   K    I+E G+EAA +  + +  I      +   N PF+F+M    T+
Sbjct: 347 EEAPLKLSKAVHKAVLTIDEKGTEAAGA--MFLEAIPMSIPPEVKFNKPFVFLMIEQNTK 404

Query: 382 SILFMGRVTNP 392
           S LFMG+V NP
Sbjct: 405 SPLFMGKVVNP 415


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.376 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,049,355
Number of Sequences: 37866
Number of extensions: 527038
Number of successful extensions: 1759
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 1468
Number of HSP's gapped (non-prelim): 77
length of query: 405
length of database: 18,247,518
effective HSP length: 105
effective length of query: 300
effective length of database: 14,271,588
effective search space: 4281476400
effective search space used: 4281476400
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.