Search of human proteins with 5453611

Search of human proteins with 5453611

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5453611 CD28 antigen precursor [Homo sapiens]
         (220 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5453611 CD28 antigen precursor [Homo sapiens]                      457   e-129
gi|21361212 cytotoxic T-lymphocyte-associated protein 4 isoform ...    73   2e-13
gi|15029518 inducible T-cell co-stimulator precursor [Homo sapiens]    54   1e-07
gi|83700231 cytotoxic T-lymphocyte-associated protein 4 isoform ...    51   7e-07
gi|4501915 ADAM metallopeptidase domain 9 isoform 1 precursor [H...    33   0.19 
gi|27363458 leucine rich repeat and fibronectin type III domain ...    31   0.73 
gi|8922281 WDYHV motif containing 1 [Homo sapiens]                     31   0.73 
gi|45827701 pad-1-like [Homo sapiens]                                  29   3.6  
gi|61743940 G-protein coupled receptor 110 isoform 1 [Homo sapiens]    29   3.6  
gi|4503493 early growth response 1 [Homo sapiens]                      28   6.1  
gi|21389351 sideroflexin 5 [Homo sapiens]                              28   6.1  

>gi|5453611 CD28 antigen precursor [Homo sapiens]
          Length = 220

 Score =  457 bits (1176), Expect = e-129
 Identities = 220/220 (100%), Positives = 220/220 (100%)

Query: 1   MLRLLLALNLFPSIQVTGNKILVKQSPMLVAYDNAVNLSCKYSYNLFSREFRASLHKGLD 60
           MLRLLLALNLFPSIQVTGNKILVKQSPMLVAYDNAVNLSCKYSYNLFSREFRASLHKGLD
Sbjct: 1   MLRLLLALNLFPSIQVTGNKILVKQSPMLVAYDNAVNLSCKYSYNLFSREFRASLHKGLD 60

Query: 61  SAVEVCVVYGNYSQQLQVYSKTGFNCDGKLGNESVTFYLQNLYVNQTDIYFCKIEVMYPP 120
           SAVEVCVVYGNYSQQLQVYSKTGFNCDGKLGNESVTFYLQNLYVNQTDIYFCKIEVMYPP
Sbjct: 61  SAVEVCVVYGNYSQQLQVYSKTGFNCDGKLGNESVTFYLQNLYVNQTDIYFCKIEVMYPP 120

Query: 121 PYLDNEKSNGTIIHVKGKHLCPSPLFPGPSKPFWVLVVVGGVLACYSLLVTVAFIIFWVR 180
           PYLDNEKSNGTIIHVKGKHLCPSPLFPGPSKPFWVLVVVGGVLACYSLLVTVAFIIFWVR
Sbjct: 121 PYLDNEKSNGTIIHVKGKHLCPSPLFPGPSKPFWVLVVVGGVLACYSLLVTVAFIIFWVR 180

Query: 181 SKRSRLLHSDYMNMTPRRPGPTRKHYQPYAPPRDFAAYRS 220
           SKRSRLLHSDYMNMTPRRPGPTRKHYQPYAPPRDFAAYRS
Sbjct: 181 SKRSRLLHSDYMNMTPRRPGPTRKHYQPYAPPRDFAAYRS 220


>gi|21361212 cytotoxic T-lymphocyte-associated protein 4 isoform a
           precursor [Homo sapiens]
          Length = 223

 Score = 73.2 bits (178), Expect = 2e-13
 Identities = 60/192 (31%), Positives = 84/192 (43%), Gaps = 12/192 (6%)

Query: 23  VKQSPMLVAYDNAV-NLSCKYSYNLFSREFRASLHKGLDSAV-EVCVVYGNYSQQLQVYS 80
           V Q  +++A    + +  C+Y+    + E R ++ +  DS V EVC        +L    
Sbjct: 40  VAQPAVVLASSRGIASFVCEYASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFLD 99

Query: 81  KTGFNCDGKLGNESVTFYLQNLYVNQTDIYFCKIEVMYPPPYLDNEKSNGTIIHVKGKHL 140
            +   C G      V   +Q L    T +Y CK+E+MYPPPY      NGT I+V     
Sbjct: 100 DS--ICTGTSSGNQVNLTIQGLRAMDTGLYICKVELMYPPPYYLG-IGNGTQIYVIDPEP 156

Query: 141 CPSPLFPGPSKPFWVLVVVGGVLACYSLLVTVAFIIFWVRSKRSRLLHSDYMNMTPRRPG 200
           CP   F       W+L  V   L  YS L+T A  +  +  KRS L    Y+ M P  P 
Sbjct: 157 CPDSDF-----LLWILAAVSSGLFFYSFLLT-AVSLSKMLKKRSPLTTGVYVKMPPTEP- 209

Query: 201 PTRKHYQPYAPP 212
              K +QPY  P
Sbjct: 210 ECEKQFQPYFIP 221


>gi|15029518 inducible T-cell co-stimulator precursor [Homo sapiens]
          Length = 199

 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 38/141 (26%), Positives = 66/141 (46%), Gaps = 9/141 (6%)

Query: 28  MLVAYDNAVNLSCKYSYNLFSREFRASLHKGLDSAVEVCVVYGNYSQQLQVYSKTGFNCD 87
           M + ++  V + CKY   +  ++F+  L KG     ++    G+ +    V  K+   C 
Sbjct: 30  MFIFHNGGVQILCKYPDIV--QQFKMQLLKGGQILCDLTKTKGSGNT---VSIKSLKFCH 84

Query: 88  GKLGNESVTFYLQNLYVNQTDIYFCKIEVMYPPPYLDNEKSNGTIIHVKGKHLCPSPLF- 146
            +L N SV+F+L NL  +  + YFC + +  PPP+       G  +H+    LC    F 
Sbjct: 85  SQLSNNSVSFFLYNLDHSHANYYFCNLSIFDPPPF--KVTLTGGYLHIYESQLCCQLKFW 142

Query: 147 -PGPSKPFWVLVVVGGVLACY 166
            P     F V+ ++G +L C+
Sbjct: 143 LPIGCAAFVVVCILGCILICW 163


>gi|83700231 cytotoxic T-lymphocyte-associated protein 4 isoform b
           precursor [Homo sapiens]
          Length = 174

 Score = 51.2 bits (121), Expect = 7e-07
 Identities = 38/123 (30%), Positives = 56/123 (45%), Gaps = 5/123 (4%)

Query: 23  VKQSPMLVAYDNAV-NLSCKYSYNLFSREFRASLHKGLDSAV-EVCVVYGNYSQQLQVYS 80
           V Q  +++A    + +  C+Y+    + E R ++ +  DS V EVC        +L    
Sbjct: 40  VAQPAVVLASSRGIASFVCEYASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFLD 99

Query: 81  KTGFNCDGKLGNESVTFYLQNLYVNQTDIYFCKIEVMYPPPYLDNEKSNGTIIHVKGKHL 140
            +   C G      V   +Q L    T +Y CK+E+MYPPPY      NGT I+V  K  
Sbjct: 100 DS--ICTGTSSGNQVNLTIQGLRAMDTGLYICKVELMYPPPYYLG-IGNGTQIYVIAKEK 156

Query: 141 CPS 143
            PS
Sbjct: 157 KPS 159


>gi|4501915 ADAM metallopeptidase domain 9 isoform 1 precursor [Homo
           sapiens]
          Length = 819

 Score = 33.1 bits (74), Expect = 0.19
 Identities = 21/68 (30%), Positives = 30/68 (44%), Gaps = 2/68 (2%)

Query: 153 FWVLVVVGGVLACYSLLVTVAFIIFWVRSKRSRLLHSDYMNMT--PRRPGPTRKHYQPYA 210
           F+ L+V   V A +  +        + R KRS+   SD  N     R+PG   +H  P  
Sbjct: 702 FFFLIVPLIVCAIFIFIKRDQLWRSYFRKKRSQTYESDGKNQANPSRQPGSVPRHVSPVT 761

Query: 211 PPRDFAAY 218
           PPR+   Y
Sbjct: 762 PPREVPIY 769


>gi|27363458 leucine rich repeat and fibronectin type III domain
           containing 4 [Homo sapiens]
          Length = 635

 Score = 31.2 bits (69), Expect = 0.73
 Identities = 21/58 (36%), Positives = 28/58 (48%), Gaps = 2/58 (3%)

Query: 157 VVVGGVLACYSLLVTVAFIIFWVRSKRSR--LLHSDYMNMTPRRPGPTRKHYQPYAPP 212
           V VGGVL    L+ TVA ++    +   R  L  S   + T   P PT K + P +PP
Sbjct: 520 VAVGGVLVAALLVFTVALLVRGRGAGNGRLPLKLSHVQSQTNGGPSPTPKAHPPRSPP 577


>gi|8922281 WDYHV motif containing 1 [Homo sapiens]
          Length = 205

 Score = 31.2 bits (69), Expect = 0.73
 Identities = 12/21 (57%), Positives = 13/21 (61%)

Query: 200 GPTRKHYQPYAPPRDFAAYRS 220
           GP   HYQP +PPRD   Y S
Sbjct: 5   GPAAVHYQPASPPRDACVYSS 25


>gi|45827701 pad-1-like [Homo sapiens]
          Length = 2298

 Score = 28.9 bits (63), Expect = 3.6
 Identities = 12/25 (48%), Positives = 17/25 (68%)

Query: 115 EVMYPPPYLDNEKSNGTIIHVKGKH 139
           +V  PP YLD E ++GT   VKG++
Sbjct: 538 KVQMPPSYLDTESTSGTSSPVKGEN 562


>gi|61743940 G-protein coupled receptor 110 isoform 1 [Homo sapiens]
          Length = 910

 Score = 28.9 bits (63), Expect = 3.6
 Identities = 26/127 (20%), Positives = 49/127 (38%), Gaps = 22/127 (17%)

Query: 85  NCDGKLGNESVTFYLQNLYVNQTDIYFCKIEVMYPPP-----------------YLDNEK 127
           N + ++    ++  +QN  +N+  ++F KIE     P                 +L NE 
Sbjct: 496 NGNAQVNGPVISTVIQNYSINEVFLFFSKIESNLSQPHCVFWDFSHLQWNDAGCHLVNET 555

Query: 128 SN---GTIIHVKGKHLCPSPLFPGPSKPF--WVLVVVGGVLACYSLLVTVAFIIFWVRSK 182
            +       H+    +  SP  P    P   W+  V  G+     +L  +   +FW + K
Sbjct: 556 QDIVTCQCTHLTSFSILMSPFVPSTIFPVVKWITYVGLGISIGSLILCLIIEALFWKQIK 615

Query: 183 RSRLLHS 189
           +S+  H+
Sbjct: 616 KSQTSHT 622


>gi|4503493 early growth response 1 [Homo sapiens]
          Length = 543

 Score = 28.1 bits (61), Expect = 6.1
 Identities = 13/32 (40%), Positives = 17/32 (53%)

Query: 181 SKRSRLLHSDYMNMTPRRPGPTRKHYQPYAPP 212
           S +S+L+    M   P RP  T  H +PYA P
Sbjct: 310 SYQSQLIKPSRMRKYPNRPSKTPPHERPYACP 341


>gi|21389351 sideroflexin 5 [Homo sapiens]
          Length = 340

 Score = 28.1 bits (61), Expect = 6.1
 Identities = 19/58 (32%), Positives = 25/58 (43%), Gaps = 4/58 (6%)

Query: 152 PFWVLVVVGGVLACYSLLVTVAFIIFWVRSKRSRLLHSDYMNMTPRRPGPTRKHYQPY 209
           PF   +VVG +L   +L  TV    FW    +S     +Y N    +P P  K  Q Y
Sbjct: 114 PFGTPIVVGLLLPNQTLASTV----FWQWLNQSHNACVNYANRNATKPSPASKFIQGY 167


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.139    0.436 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,510,319
Number of Sequences: 37866
Number of extensions: 434149
Number of successful extensions: 963
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 953
Number of HSP's gapped (non-prelim): 12
length of query: 220
length of database: 18,247,518
effective HSP length: 98
effective length of query: 122
effective length of database: 14,536,650
effective search space: 1773471300
effective search space used: 1773471300
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.