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Search of human proteins with 54234057
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|54234057 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 6 [Homo sapiens]
(398 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|54234057 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltrans... 809 0.0
gi|4506953 alpha-2,8-sialyltransferase 1 [Homo sapiens] 274 9e-74
gi|28373101 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltrans... 264 9e-71
gi|110815855 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltran... 182 6e-46
gi|5031999 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf... 151 9e-37
gi|5174677 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf... 149 4e-36
gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [... 72 7e-13
gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [H... 72 7e-13
gi|21264332 sialyltransferase 7A [Homo sapiens] 70 4e-12
gi|192448440 sialyltransferase 7B [Homo sapiens] 69 1e-11
gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 i... 60 3e-09
gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 ... 60 3e-09
gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [H... 60 5e-09
gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2... 59 1e-08
gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 ... 59 1e-08
gi|13569938 sialyltransferase 7E [Homo sapiens] 55 1e-07
gi|28373099 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltrans... 55 1e-07
gi|28373092 sialyltransferase 7D isoform a [Homo sapiens] 52 7e-07
gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens] 49 1e-05
gi|21361444 sialytransferase 7F [Homo sapiens] 48 1e-05
gi|28373086 sialyltransferase 6 isoform i [Homo sapiens] 48 2e-05
gi|28373082 sialyltransferase 6 isoform g [Homo sapiens] 48 2e-05
gi|28373078 sialyltransferase 6 isoform f [Homo sapiens] 48 2e-05
gi|28373070 sialyltransferase 6 isoform b [Homo sapiens] 48 2e-05
gi|28373068 sialyltransferase 6 isoform a [Homo sapiens] 48 2e-05
gi|5454060 sialyltransferase 6 isoform j [Homo sapiens] 48 2e-05
gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2... 47 2e-05
gi|28373074 sialyltransferase 6 isoform d [Homo sapiens] 47 3e-05
gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [H... 45 1e-04
gi|229892273 sialyltransferase 7C isoform 1 [Homo sapiens] 41 0.002
>gi|54234057 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 6 [Homo sapiens]
Length = 398
Score = 809 bits (2089), Expect = 0.0
Identities = 398/398 (100%), Positives = 398/398 (100%)
Query: 1 MRPGGALLALLASLLLLLLLRLLWCPADAPGRARILVEESREATHGTPAALRTLRSPATA 60
MRPGGALLALLASLLLLLLLRLLWCPADAPGRARILVEESREATHGTPAALRTLRSPATA
Sbjct: 1 MRPGGALLALLASLLLLLLLRLLWCPADAPGRARILVEESREATHGTPAALRTLRSPATA 60
Query: 61 VPRATNSTYLNEKSLQLTEKCKNLQYGIESFSNKTKGYSENDYLQIITDIQSCPWKRQAE 120
VPRATNSTYLNEKSLQLTEKCKNLQYGIESFSNKTKGYSENDYLQIITDIQSCPWKRQAE
Sbjct: 61 VPRATNSTYLNEKSLQLTEKCKNLQYGIESFSNKTKGYSENDYLQIITDIQSCPWKRQAE 120
Query: 121 EYANFRAKLASCCDAVQNFVVSQNNTPVGTNMSYEVESKKEIPIKKNIFHMFPVSQPFVD 180
EYANFRAKLASCCDAVQNFVVSQNNTPVGTNMSYEVESKKEIPIKKNIFHMFPVSQPFVD
Sbjct: 121 EYANFRAKLASCCDAVQNFVVSQNNTPVGTNMSYEVESKKEIPIKKNIFHMFPVSQPFVD 180
Query: 181 YPYNQCAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSII 240
YPYNQCAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSII
Sbjct: 181 YPYNQCAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSII 240
Query: 241 TLKYGNLKEKKALFLEDIATYGDAFFLLPAFSFRANTGTSFKVYYTLEESKARQKVLFFH 300
TLKYGNLKEKKALFLEDIATYGDAFFLLPAFSFRANTGTSFKVYYTLEESKARQKVLFFH
Sbjct: 241 TLKYGNLKEKKALFLEDIATYGDAFFLLPAFSFRANTGTSFKVYYTLEESKARQKVLFFH 300
Query: 301 PKYLKDLALFWRTKGVTAYRLSTGLMITSVAVELCKNVKLYGFWPFSKTVEDIPVSHHYY 360
PKYLKDLALFWRTKGVTAYRLSTGLMITSVAVELCKNVKLYGFWPFSKTVEDIPVSHHYY
Sbjct: 301 PKYLKDLALFWRTKGVTAYRLSTGLMITSVAVELCKNVKLYGFWPFSKTVEDIPVSHHYY 360
Query: 361 DNKLPKHGFHQMPKEYSQILQLHMKGILKLQFSKCEVA 398
DNKLPKHGFHQMPKEYSQILQLHMKGILKLQFSKCEVA
Sbjct: 361 DNKLPKHGFHQMPKEYSQILQLHMKGILKLQFSKCEVA 398
>gi|4506953 alpha-2,8-sialyltransferase 1 [Homo sapiens]
Length = 356
Score = 274 bits (701), Expect = 9e-74
Identities = 127/286 (44%), Positives = 183/286 (63%), Gaps = 1/286 (0%)
Query: 111 QSCPWKRQAEEYANFRAKLASCCDAVQNFVVSQNNTPVGTNMSYEVESKKEIPIKKNIFH 170
Q W+R FR ++ CCD F +++ N+P+G +M Y+ E I + +
Sbjct: 64 QGTAWRRNQTAARAFRKQMEDCCDPAHLFAMTKMNSPMGKSMWYDGEFLYSFTIDNSTYS 123
Query: 171 MFPVSQPFVDYPYNQCAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKT 230
+FP + PF P +CAVVGNGGIL KS CG +ID+++FV RCNLPP + + +KDVGSK+
Sbjct: 124 LFPQATPF-QLPLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKS 182
Query: 231 NLVTINPSIITLKYGNLKEKKALFLEDIATYGDAFFLLPAFSFRANTGTSFKVYYTLEES 290
LVT NPSII ++ NL + F++++ Y ++ +PAFS + T S +VYYTL +
Sbjct: 183 QLVTANPSIIRQRFQNLLWSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLSDV 242
Query: 291 KARQKVLFFHPKYLKDLALFWRTKGVTAYRLSTGLMITSVAVELCKNVKLYGFWPFSKTV 350
A Q VLF +P +L+ + FW+++G+ A RLSTGL + S A+ LC+ V +YGFWPFS +
Sbjct: 243 GANQTVLFANPNFLRSIGKFWKSRGIHAKRLSTGLFLVSAALGLCEEVAIYGFWPFSVNM 302
Query: 351 EDIPVSHHYYDNKLPKHGFHQMPKEYSQILQLHMKGILKLQFSKCE 396
+ P+SHHYYDN LP GFH MP+E+ Q+ LH G L++Q CE
Sbjct: 303 HEQPISHHYYDNVLPFSGFHAMPEEFLQLWYLHKIGALRMQLDPCE 348
>gi|28373101 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 5 [Homo sapiens]
Length = 376
Score = 264 bits (675), Expect = 9e-71
Identities = 124/286 (43%), Positives = 178/286 (62%)
Query: 110 IQSCPWKRQAEEYANFRAKLASCCDAVQNFVVSQNNTPVGTNMSYEVESKKEIPIKKNIF 169
+Q C W E F++ L+ CC+A +Q NTP+GT + YEV++ I + IF
Sbjct: 88 LQMCKWAMNISEANQFKSTLSRCCNAPAFLFTTQKNTPLGTKLKYEVDTSGIYHINQEIF 147
Query: 170 HMFPVSQPFVDYPYNQCAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSK 229
MFP P+ + +CAVVGNGGIL S CG EI+ +DFVFRCNLPP + + DVG K
Sbjct: 148 RMFPKDMPYYRSQFKKCAVVGNGGILKNSRCGREINSADFVFRCNLPPISEKYTMDVGVK 207
Query: 230 TNLVTINPSIITLKYGNLKEKKALFLEDIATYGDAFFLLPAFSFRANTGTSFKVYYTLEE 289
T++VT+NPSIIT ++ L++ + F + Y +A LLPAF NT S +V Y L++
Sbjct: 208 TDVVTVNPSIITERFHKLEKWRRPFYRVLQVYENASVLLPAFYNTRNTDVSIRVKYVLDD 267
Query: 290 SKARQKVLFFHPKYLKDLALFWRTKGVTAYRLSTGLMITSVAVELCKNVKLYGFWPFSKT 349
++ Q V +FHP+YL +++ +W + GV A R+STGL++ + A+ELC+ V L+GFW F
Sbjct: 268 FESPQAVYYFHPQYLVNVSRYWLSLGVRAKRISTGLILVTAALELCEEVHLFGFWAFPMN 327
Query: 350 VEDIPVSHHYYDNKLPKHGFHQMPKEYSQILQLHMKGILKLQFSKC 395
+ ++HHYYDN P+ GFH MP E L LH +GIL++ C
Sbjct: 328 PSGLYITHHYYDNVKPRPGFHAMPSEIFNFLHLHSRGILRVHTGTC 373
>gi|110815855 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 3 [Homo sapiens]
Length = 380
Score = 182 bits (461), Expect = 6e-46
Identities = 106/294 (36%), Positives = 158/294 (53%), Gaps = 17/294 (5%)
Query: 115 WKRQAEEYANFRAKLASCCDAVQNFVVSQNNTPVGTNMSYEVESKKEI-PIKKNIFHMFP 173
WK + + R ++ D ++NF +++N+ +G M Y+ S K + I N + P
Sbjct: 90 WKFNRTAFLHQRQEILQHVDVIKNFSLTKNSVRIGQLMHYDYSSHKYVFSISNNFRSLLP 149
Query: 174 VSQPFVDYPYNQCAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLV 233
P ++ YN CAVVGN GIL S CG EIDKSDFVFRCN PT +DVG KTNL
Sbjct: 150 DVSPIMNKHYNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEA-FQRDVGRKTNLT 208
Query: 234 TINPSIITLKYGNL---KEKKALFLEDIATYGDAFFLLPAFSFRANTGTSFKVYYTLEES 290
T NPSI+ Y NL +++ FL + A +PAF F + + + E
Sbjct: 209 TFNPSILEKYYNNLLTIQDRNNFFL-SLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEH 267
Query: 291 KARQKVLFFHP-KYLKDLALFWRTKGVTAYRLSTGLMITSVAVELCKNVKLYGFWPFS-- 347
+ + KV P ++ + +W+ K ++ RLSTG+++ ++A +C+ + LYGFWPF
Sbjct: 268 RGQLKVQLAWPGNIMQHVNRYWKNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGFD 327
Query: 348 -KTVEDIPVSHHYYDNKLPK-----HGFHQMPKEYSQILQLHMKGILKLQFSKC 395
T ED+P +HYYD K K HQ+P E+ + ++H +G+ KL S C
Sbjct: 328 PNTREDLP--YHYYDKKGTKFTTKWQESHQLPAEFQLLYRMHGEGLTKLTLSHC 379
>gi|5031999 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 4 isoform a [Homo sapiens]
Length = 359
Score = 151 bits (382), Expect = 9e-37
Identities = 84/287 (29%), Positives = 146/287 (50%), Gaps = 7/287 (2%)
Query: 115 WKRQAEEYANFRAKLASCCDAVQNFVVSQNNTPVGTNMSYEVESKKEIPIKKNIFHMFPV 174
WK + R + DA ++ V +++ G + Y ++ ++ + I ++ + P
Sbjct: 71 WKINSSLVLEIRKNILRFLDAERDVSVVKSSFKPGDVIHYVLDRRRTLNISHDLHSLLPE 130
Query: 175 SQPFVDYPYNQCAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVT 234
P + + CAVVGN GIL S CG EID +FV RCNL P + + DVG+K++ +T
Sbjct: 131 VSPMKNRRFKTCAVVGNSGILLDSECGKEIDSHNFVIRCNLAPVV-EFAADVGTKSDFIT 189
Query: 235 INPSIITLKYGNLKEK--KALFLEDIATYGDAFFLLPAFSFRANTGTSFKVYYTLEESKA 292
+NPS++ +G + + + F+ ++ D+ +PAF + V + ++K
Sbjct: 190 MNPSVVQRAFGGFRNESDREKFVHRLSMLNDSVLWIPAFMVKGGEKHVEWVNALILKNKL 249
Query: 293 RQKVLFFHPKYLKDLALFWRTKGVTAYRLSTGLMITSVAVELCKNVKLYGFWPFSKTVED 352
+ + + + + + +W T V R STGL++ ++A C + LYGFWPF K +
Sbjct: 250 KVRTAYPSLRLIHAVRGYWLTNKVPIKRPSTGLLMYTLATRFCDEIHLYGFWPFPKDLNG 309
Query: 353 IPVSHHYYDNKLPKH----GFHQMPKEYSQILQLHMKGILKLQFSKC 395
V +HYYD+ ++ H+MP E+ + LH +G LKL KC
Sbjct: 310 KAVKYHYYDDLKYRYFSNASPHRMPLEFKTLNVLHNRGALKLTTGKC 356
>gi|5174677 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 2 [Homo sapiens]
Length = 375
Score = 149 bits (376), Expect = 4e-36
Identities = 88/295 (29%), Positives = 143/295 (48%), Gaps = 11/295 (3%)
Query: 112 SCPWKRQAEEYANFRAKLASCCDAVQNFVVSQNNTPVGTNMSYEVESKKEIPIKKNIFHM 171
S W+ R ++ DA ++ V + G + Y + + + +N++ +
Sbjct: 83 SSKWRHNQTLSLRIRKQILKFLDAEKDISVLKGTLKPGDIIHYIFDRDSTMNVSQNLYEL 142
Query: 172 FPVSQPFVDYPYNQCAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTN 231
P + P + + CA+VGN G+L S CG EID FV RCNL P + ++DVG KT+
Sbjct: 143 LPRTSPLKNKHFGTCAIVGNSGVLLNSGCGQEIDAHSFVIRCNLAPVQ-EYARDVGLKTD 201
Query: 232 LVTINPSIITLKYGNLKEK--KALFLEDIATYGDAFFLLPAFSFRANTGTSFKVYYTLEE 289
LVT+NPS+I + +L + L+ + + + +PAF R V + +
Sbjct: 202 LVTMNPSVIQRAFEDLVNATWREKLLQRLHSLNGSILWIPAFMARGGKERVEWVNELILK 261
Query: 290 SKARQKVLFFHPKYLKDLALFWRTKGVTAYRLSTGLMITSVAVELCKNVKLYGFWPFSKT 349
+ + + L + +W T V R +TGL++ ++A CK + LYGFWPF
Sbjct: 262 HHVNVRTAYPSLRLLHAVRGYWLTNKVHIKRPTTGLLMYTLATRFCKQIYLYGFWPFPLD 321
Query: 350 VEDIPVSHHYYDNKLPKHGF------HQMPKEYSQILQLHMKGILKLQFSKCEVA 398
PV +HYYD+ K+G+ H MP E+ + LH +G LKL +C+ A
Sbjct: 322 QNQNPVKYHYYDSL--KYGYTSQASPHTMPLEFKALKSLHEQGALKLTVGQCDGA 374
>gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
[Homo sapiens]
Length = 340
Score = 72.4 bits (176), Expect = 7e-13
Identities = 59/180 (32%), Positives = 86/180 (47%), Gaps = 19/180 (10%)
Query: 185 QCAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSIITLKY 244
+CAVVGN G L +S G EID DFV R N PT G DVG+KT + P +
Sbjct: 141 RCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAG-FEADVGTKTTHHLVYPE----SF 195
Query: 245 GNLKEKKALFLEDIATYGDAFFLLPAFSFRANTGTSFKVYYTLEES--KARQKVLFFHPK 302
L + ++ L T D +++ A + TGT Y + + K+L +HP
Sbjct: 196 RELGDNVSMILVPFKTI-DLEWVVSAIT----TGTISHTYIPVPAKIRVKQDKILIYHPA 250
Query: 303 YLKDLALFWRTKGVTAYRLSTGLMITSVAVELCKNVKLYGFWPFSKTVEDIPVSHHYYDN 362
++K + W +G Y STG++ ++ +C V LYGF SK HHY++N
Sbjct: 251 FIKYVFDNW-LQGHGRYP-STGILSVIFSMHVCDEVDLYGFGADSK-----GNWHHYWEN 303
>gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [Homo
sapiens]
Length = 340
Score = 72.4 bits (176), Expect = 7e-13
Identities = 59/180 (32%), Positives = 86/180 (47%), Gaps = 19/180 (10%)
Query: 185 QCAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSIITLKY 244
+CAVVGN G L +S G EID DFV R N PT G DVG+KT + P +
Sbjct: 141 RCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAG-FEADVGTKTTHHLVYPE----SF 195
Query: 245 GNLKEKKALFLEDIATYGDAFFLLPAFSFRANTGTSFKVYYTLEES--KARQKVLFFHPK 302
L + ++ L T D +++ A + TGT Y + + K+L +HP
Sbjct: 196 RELGDNVSMILVPFKTI-DLEWVVSAIT----TGTISHTYIPVPAKIRVKQDKILIYHPA 250
Query: 303 YLKDLALFWRTKGVTAYRLSTGLMITSVAVELCKNVKLYGFWPFSKTVEDIPVSHHYYDN 362
++K + W +G Y STG++ ++ +C V LYGF SK HHY++N
Sbjct: 251 FIKYVFDNW-LQGHGRYP-STGILSVIFSMHVCDEVDLYGFGADSK-----GNWHHYWEN 303
>gi|21264332 sialyltransferase 7A [Homo sapiens]
Length = 600
Score = 69.7 bits (169), Expect = 4e-12
Identities = 71/234 (30%), Positives = 101/234 (43%), Gaps = 40/234 (17%)
Query: 186 CAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNL-----VTINPSII 240
CAVVGNGGILN S G EID D+VFR + G +DVG++T+ ++ S++
Sbjct: 365 CAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKG-YEQDVGTRTSFYGFTAFSLTQSLL 423
Query: 241 TLKYGNLKE-------KKALFLEDIATYGDAFFLL--------PAFSFRANTGTSFKVYY 285
L K + FLE Y LL F FR +F+
Sbjct: 424 ILGNRGFKNVPLGKDVRYLHFLEGTRDYEWLEALLMNQTVMSKNLFWFRHRPQEAFR--- 480
Query: 286 TLEESKARQKVLFFHPKYLKDLA-LFWRTKGVTA-----YRLSTGLMITSVAVELCKNVK 339
E+ + L HP +L+ + F R+K + YR +TG ++ A++LC V
Sbjct: 481 ---EALHMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVS 537
Query: 340 LYGFWPFSKTVEDIPVSHHYYDNKLPKHGF---HQMPKEYSQILQLHMKGILKL 390
YGF T S HYYD + F H E +LH +GI++L
Sbjct: 538 AYGF----ITEGHERFSDHYYDTSWKRLIFYINHDFKLEREVWKRLHDEGIIRL 587
>gi|192448440 sialyltransferase 7B [Homo sapiens]
Length = 374
Score = 68.6 bits (166), Expect = 1e-11
Identities = 73/235 (31%), Positives = 106/235 (45%), Gaps = 42/235 (17%)
Query: 185 QCAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNL--VTINPSIITL 242
+CAVVGNGGILN S G ID D+VFR N G +DVG+KT+ T+N +L
Sbjct: 150 RCAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKG-FERDVGTKTSFYGFTVNTMKNSL 208
Query: 243 -KYGNL--------KEKKALFL-EDIATY---GDAFFLLPAFSFRANTGTSFKVYYTLEE 289
Y NL ++ + +F+ DI Y A +P + G Y+ E
Sbjct: 209 VSYWNLGFTSVPQGQDLQYIFIPSDIRDYVMLRSAILGVPV-PEGLDKGDRPHAYFGPEA 267
Query: 290 SKARQKVLFFHPKYLKDLA-LFWRTKGVTA-----YRLSTGLMITSVAVELCKNVKLYGF 343
S ++ K+L HP ++ L F ++K + Y STG ++ A+ C V YGF
Sbjct: 268 SASKFKLL--HPDFISYLTERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAYGF 325
Query: 344 -----WPFSKTVEDIPVSHHYYDNKLPK---HGFHQMPKEYSQILQLHMKGILKL 390
W F S HY++ K+ + H + E + LH GIL+L
Sbjct: 326 ITSNYWKF---------SDHYFERKMKPLIFYANHDLSLEAALWRDLHKAGILQL 371
>gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
isoform a [Homo sapiens]
Length = 406
Score = 60.1 bits (144), Expect = 3e-09
Identities = 52/211 (24%), Positives = 93/211 (44%), Gaps = 16/211 (7%)
Query: 182 PYNQCAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSIIT 241
P+ +CAVV + G L S G EID D V R N P T + +DVG+KT + +N ++T
Sbjct: 180 PWGRCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAP-TANFQQDVGTKTTIRLMNSQLVT 238
Query: 242 LKYGNLKEKKALFLEDIATYGD---------AFFLLPAFSFRANTGTSFKVYYTLEESKA 292
+ LK+ +L+ E I D ++ P ++F N +K Y L ++
Sbjct: 239 TEKRFLKD--SLYNEGILIVWDPSVYHSDIPKWYQNPDYNFFNN----YKTYRKLHPNQP 292
Query: 293 RQKVLFFHPKYLKDLALFWRTKGVTAYRLSTGLMITSVAVELCKNVKLYGFWPFSKTVED 352
+ P L D+ + + S+G++ + + LC V +Y F P + +
Sbjct: 293 FYILKPQMPWELWDILQEISPEEIQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSKRKTDV 352
Query: 353 IPVSHHYYDNKLPKHGFHQMPKEYSQILQLH 383
++D+ +H + E + + L+
Sbjct: 353 CYYYQKFFDSACTMGAYHPLLYEKNLVKHLN 383
>gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
isoform a [Homo sapiens]
Length = 406
Score = 60.1 bits (144), Expect = 3e-09
Identities = 52/211 (24%), Positives = 93/211 (44%), Gaps = 16/211 (7%)
Query: 182 PYNQCAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSIIT 241
P+ +CAVV + G L S G EID D V R N P T + +DVG+KT + +N ++T
Sbjct: 180 PWGRCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAP-TANFQQDVGTKTTIRLMNSQLVT 238
Query: 242 LKYGNLKEKKALFLEDIATYGD---------AFFLLPAFSFRANTGTSFKVYYTLEESKA 292
+ LK+ +L+ E I D ++ P ++F N +K Y L ++
Sbjct: 239 TEKRFLKD--SLYNEGILIVWDPSVYHSDIPKWYQNPDYNFFNN----YKTYRKLHPNQP 292
Query: 293 RQKVLFFHPKYLKDLALFWRTKGVTAYRLSTGLMITSVAVELCKNVKLYGFWPFSKTVED 352
+ P L D+ + + S+G++ + + LC V +Y F P + +
Sbjct: 293 FYILKPQMPWELWDILQEISPEEIQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSKRKTDV 352
Query: 353 IPVSHHYYDNKLPKHGFHQMPKEYSQILQLH 383
++D+ +H + E + + L+
Sbjct: 353 CYYYQKFFDSACTMGAYHPLLYEKNLVKHLN 383
>gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [Homo
sapiens]
Length = 350
Score = 59.7 bits (143), Expect = 5e-09
Identities = 57/202 (28%), Positives = 89/202 (44%), Gaps = 18/202 (8%)
Query: 164 IKKNIFHMFPVSQPFV---DYPYNQCAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTG 220
+ + +F + P P+ + +CAVVGN G L S G ++D +F+ R N PT G
Sbjct: 127 VLEKLFQIVPGENPYRFRDPHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVG 186
Query: 221 DVSKDVGSKTNLVTINPSIITLKYGNLKEKKALFLEDIATYGDAFFLLPAFSFRANTGTS 280
+DVGS+T + P NL + L D ++ A S T
Sbjct: 187 -FEQDVGSRTTHHFMYPE----SAKNLPANVSFVLVPFKVL-DLLWIASALSTGQIRFTY 240
Query: 281 FKVYYTLEESKARQKVLFFHPKYLKDLALFWRTKGVTAYRLSTGLMITSVAVELCKNVKL 340
V L K +KV ++P + K + W T+ Y STG+++ A+ +C V +
Sbjct: 241 APVKSFLRVDK--EKVQIYNPAFFKYIHDRW-TEHHGRYP-STGMLVLFFALHVCDEVNV 296
Query: 341 YGFWPFSKTVEDIPVSHHYYDN 362
YGF S+ HHY++N
Sbjct: 297 YGFGADSR-----GNWHHYWEN 313
>gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform a [Homo sapiens]
Length = 529
Score = 58.5 bits (140), Expect = 1e-08
Identities = 55/210 (26%), Positives = 86/210 (40%), Gaps = 19/210 (9%)
Query: 186 CAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSIIT---- 241
CAVV + G + S G EID D V R N PT G KDVG+KT + IN I+T
Sbjct: 296 CAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRG-YEKDVGNKTTIRIINSQILTNPSH 354
Query: 242 -LKYGNLKEKKALFLEDIATYG---DAFFLLPAFSFRANTGTSFKVYYTLEESKARQKVL 297
+L + L D A Y + ++ P ++ F Y + Q
Sbjct: 355 HFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNL-------FTPYIQHRQRNPNQPFY 407
Query: 298 FFHPKY---LKDLALFWRTKGVTAYRLSTGLMITSVAVELCKNVKLYGFWPFSKTVEDIP 354
HPK+ L D+ + + S+G + + + +C+ V +Y + P + E
Sbjct: 408 ILHPKFIWQLWDIIQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCH 467
Query: 355 VSHHYYDNKLPKHGFHQMPKEYSQILQLHM 384
YYD +H + E + +L+M
Sbjct: 468 YHELYYDAACTLGAYHPLLYEKLLVQRLNM 497
>gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform a [Homo sapiens]
Length = 529
Score = 58.5 bits (140), Expect = 1e-08
Identities = 55/210 (26%), Positives = 86/210 (40%), Gaps = 19/210 (9%)
Query: 186 CAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSIIT---- 241
CAVV + G + S G EID D V R N PT G KDVG+KT + IN I+T
Sbjct: 296 CAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRG-YEKDVGNKTTIRIINSQILTNPSH 354
Query: 242 -LKYGNLKEKKALFLEDIATYG---DAFFLLPAFSFRANTGTSFKVYYTLEESKARQKVL 297
+L + L D A Y + ++ P ++ F Y + Q
Sbjct: 355 HFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNL-------FTPYIQHRQRNPNQPFY 407
Query: 298 FFHPKY---LKDLALFWRTKGVTAYRLSTGLMITSVAVELCKNVKLYGFWPFSKTVEDIP 354
HPK+ L D+ + + S+G + + + +C+ V +Y + P + E
Sbjct: 408 ILHPKFIWQLWDIIQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCH 467
Query: 355 VSHHYYDNKLPKHGFHQMPKEYSQILQLHM 384
YYD +H + E + +L+M
Sbjct: 468 YHELYYDAACTLGAYHPLLYEKLLVQRLNM 497
>gi|13569938 sialyltransferase 7E [Homo sapiens]
Length = 336
Score = 55.1 bits (131), Expect = 1e-07
Identities = 53/185 (28%), Positives = 84/185 (45%), Gaps = 16/185 (8%)
Query: 186 CAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSIITLKYG 245
CA+V + G L S G++ID+++ V R N PT G +DVG++T+L I S I
Sbjct: 96 CALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRG-YGRDVGNRTSLRVIAHSSIQRILR 154
Query: 246 NLKEKKALFLEDIATYGDAFFLLPAFSF--RANTGTSFKVYYTLEESKARQKV-LFFHPK 302
N + + + G F S+ R G + + L + R K + K
Sbjct: 155 NRHDLLNV------SQGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVLPRLKAFMITRHK 208
Query: 303 YLKDLALFWRTKG----VTAYRLSTGLMITSVAVELCKNVKLYGFWP--FSKTVEDIPVS 356
L+ LF + G ++ LSTG ++A+ELC + +YG P F + V
Sbjct: 209 MLQFDELFKQETGKDRKISNTWLSTGWFTMTIALELCDRINVYGMVPPDFCRDPNHPSVP 268
Query: 357 HHYYD 361
+HYY+
Sbjct: 269 YHYYE 273
>gi|28373099 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 4 isoform b [Homo sapiens]
Length = 168
Score = 54.7 bits (130), Expect = 1e-07
Identities = 29/98 (29%), Positives = 48/98 (48%)
Query: 115 WKRQAEEYANFRAKLASCCDAVQNFVVSQNNTPVGTNMSYEVESKKEIPIKKNIFHMFPV 174
WK + R + DA ++ V +++ G + Y ++ ++ + I ++ + P
Sbjct: 71 WKINSSLVLEIRKNILRFLDAERDVSVVKSSFKPGDVIHYVLDRRRTLNISHDLHSLLPE 130
Query: 175 SQPFVDYPYNQCAVVGNGGILNKSLCGTEIDKSDFVFR 212
P + + CAVVGN GIL S CG EID +FV R
Sbjct: 131 VSPMKNRRFKTCAVVGNSGILLDSECGKEIDSHNFVIR 168
>gi|28373092 sialyltransferase 7D isoform a [Homo sapiens]
Length = 302
Score = 52.4 bits (124), Expect = 7e-07
Identities = 49/209 (23%), Positives = 94/209 (44%), Gaps = 18/209 (8%)
Query: 163 PIKKNIFHMFPVSQPFVDYPYNQCAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDV 222
P+ + + P +P V P CAVV + G + S G EID ++ VFR N PT G
Sbjct: 53 PLHFSGYSSVPDGKPLVREPCRSCAVVSSSGQMLGSGLGAEIDSAECVFRMNQAPTVG-F 111
Query: 223 SKDVGSKTNLVTINPSIITLKYGNL-----KEKKALFLEDIATYGDAFFL---LPAFSFR 274
DVG ++ L ++ + + L N K + L++ +G + L ++R
Sbjct: 112 EADVGQRSTLRVVSHTSVPLLLRNYSHYFQKARDTLYM----VWGQGRHMDRVLGGRTYR 167
Query: 275 ANTGTSFKVYYTLEESKARQKVLFFHPKYLKDLALFWRTKGVTAYRLSTGLMITSVAVEL 334
+ ++Y L+ ++++ + + +D + + + LSTG +A+EL
Sbjct: 168 TLLQLT-RMYPGLQVYTFTERMMAYCDQIFQDET--GKNRRQSGSFLSTGWFTMILALEL 224
Query: 335 CKNVKLYGFW--PFSKTVEDIPVSHHYYD 361
C+ + +YG + + V +HY++
Sbjct: 225 CEEIVVYGMVSDSYCREKSHPSVPYHYFE 253
>gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens]
Length = 331
Score = 48.5 bits (114), Expect = 1e-05
Identities = 52/223 (23%), Positives = 87/223 (39%), Gaps = 22/223 (9%)
Query: 178 FVDYPYNQCAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINP 237
F + P +C VVGNGG+L G +ID D + R N P G ++VG +T P
Sbjct: 110 FDNIPCKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGH-EEEVGRRTTFRLFYP 168
Query: 238 SIITLKYGNLKEKKALFLEDIATYGDAFFLLPAFSFRANTGTSFK-----VYYTLEESKA 292
+ + + L + + L + NT +K + Y + +
Sbjct: 169 ESVFSDPIHNDPNTTVILTAFKPHDLRWLLELLMGDKINTNGFWKKPALNLIYKPYQIRI 228
Query: 293 RQKVLFFHPKYLKDLALFWRT--KGVTAYRLSTGLMITSVAVELCKNVKLYGFWPFSKTV 350
+ Y +L F + K +TG++ ++A +C V L G F
Sbjct: 229 LDPFIIRTAAY--ELLHFPKVFPKNQKPKHPTTGIIAITLAFYICHEVHLAG---FKYNF 283
Query: 351 EDIPVSHHYYDNK----LPKHGFHQMPKEYSQILQLHMKGILK 389
D+ HYY N + K+ +H + E QL +K I++
Sbjct: 284 SDLKSPLHYYGNATMSLMNKNAYHNVTAE-----QLFLKDIIE 321
>gi|21361444 sialytransferase 7F [Homo sapiens]
Length = 333
Score = 48.1 bits (113), Expect = 1e-05
Identities = 53/219 (24%), Positives = 86/219 (39%), Gaps = 46/219 (21%)
Query: 184 NQCAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKT------------- 230
+QC +V + L + G EI++++ R N PTTG S DVG+KT
Sbjct: 106 HQCVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTTG-YSADVGNKTTYRVVAHSSVFRV 164
Query: 231 -----NLVTINPSIITLKYG---NLKEKKALFLEDIATYGDAFFLLPAFSFRANTGTSFK 282
V P + + +G +++ + + I G F + A++ F
Sbjct: 165 LRRPQEFVNRTPETVFIFWGPPSKMQKPQGSLVRVIQRAGLVFPNMEAYAVSPGRMRQFD 224
Query: 283 VYYTLEESKARQKVLFFHPKYLKDLALFWRTKGVTAYRLSTGLMITSVAVELCKNVKLYG 342
+ E K R+K + W LSTG +AVELC +V +YG
Sbjct: 225 DLFRGETGKDREK------------SHSW---------LSTGWFTMVIAVELCDHVHVYG 263
Query: 343 FWP---FSKTVEDIPVSHHYYDNKLPKHGFHQMPKEYSQ 378
P S+ + +HYY+ K P + E+S+
Sbjct: 264 MVPPNYCSQRPRLQRMPYHYYEPKGPDECVTYIQNEHSR 302
>gi|28373086 sialyltransferase 6 isoform i [Homo sapiens]
Length = 413
Score = 47.8 bits (112), Expect = 2e-05
Identities = 50/189 (26%), Positives = 80/189 (42%), Gaps = 22/189 (11%)
Query: 185 QCAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSIITLKY 244
+C +VGNGG+L G+ ID D V R N P G KDVGSKT L P ++
Sbjct: 197 RCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKG-FEKDVGSKTTLRITYPE-GAMQR 254
Query: 245 GNLKEKKALFLEDIATYGDAFFL-LPAFSFRANTGTSFKVYYTLEESKARQKVLFFHPKY 303
E+ +LF+ + D +L + R + F K ++ +P +
Sbjct: 255 PEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYF 314
Query: 304 LKDLALFWRTKGVTAYRLSTGLM-------ITSVAVEL----CKNVKLYGFWPFSKTVED 352
+++ A + + GLM + SVAV + C V + GF + + +
Sbjct: 315 IQEAAF-----TLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGF-GYDMSTPN 368
Query: 353 IPVSHHYYD 361
P+ HYY+
Sbjct: 369 APL--HYYE 375
>gi|28373082 sialyltransferase 6 isoform g [Homo sapiens]
Length = 359
Score = 47.8 bits (112), Expect = 2e-05
Identities = 50/189 (26%), Positives = 80/189 (42%), Gaps = 22/189 (11%)
Query: 185 QCAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSIITLKY 244
+C +VGNGG+L G+ ID D V R N P G KDVGSKT L P ++
Sbjct: 143 RCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKG-FEKDVGSKTTLRITYPE-GAMQR 200
Query: 245 GNLKEKKALFLEDIATYGDAFFL-LPAFSFRANTGTSFKVYYTLEESKARQKVLFFHPKY 303
E+ +LF+ + D +L + R + F K ++ +P +
Sbjct: 201 PEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYF 260
Query: 304 LKDLALFWRTKGVTAYRLSTGLM-------ITSVAVEL----CKNVKLYGFWPFSKTVED 352
+++ A + + GLM + SVAV + C V + GF + + +
Sbjct: 261 IQEAAF-----TLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGF-GYDMSTPN 314
Query: 353 IPVSHHYYD 361
P+ HYY+
Sbjct: 315 APL--HYYE 321
>gi|28373078 sialyltransferase 6 isoform f [Homo sapiens]
Length = 429
Score = 47.8 bits (112), Expect = 2e-05
Identities = 50/189 (26%), Positives = 80/189 (42%), Gaps = 22/189 (11%)
Query: 185 QCAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSIITLKY 244
+C +VGNGG+L G+ ID D V R N P G KDVGSKT L P ++
Sbjct: 213 RCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKG-FEKDVGSKTTLRITYPE-GAMQR 270
Query: 245 GNLKEKKALFLEDIATYGDAFFL-LPAFSFRANTGTSFKVYYTLEESKARQKVLFFHPKY 303
E+ +LF+ + D +L + R + F K ++ +P +
Sbjct: 271 PEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYF 330
Query: 304 LKDLALFWRTKGVTAYRLSTGLM-------ITSVAVEL----CKNVKLYGFWPFSKTVED 352
+++ A + + GLM + SVAV + C V + GF + + +
Sbjct: 331 IQEAAF-----TLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGF-GYDMSTPN 384
Query: 353 IPVSHHYYD 361
P+ HYY+
Sbjct: 385 APL--HYYE 391
>gi|28373070 sialyltransferase 6 isoform b [Homo sapiens]
Length = 390
Score = 47.8 bits (112), Expect = 2e-05
Identities = 50/189 (26%), Positives = 80/189 (42%), Gaps = 22/189 (11%)
Query: 185 QCAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSIITLKY 244
+C +VGNGG+L G+ ID D V R N P G KDVGSKT L P ++
Sbjct: 174 RCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKG-FEKDVGSKTTLRITYPE-GAMQR 231
Query: 245 GNLKEKKALFLEDIATYGDAFFL-LPAFSFRANTGTSFKVYYTLEESKARQKVLFFHPKY 303
E+ +LF+ + D +L + R + F K ++ +P +
Sbjct: 232 PEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYF 291
Query: 304 LKDLALFWRTKGVTAYRLSTGLM-------ITSVAVEL----CKNVKLYGFWPFSKTVED 352
+++ A + + GLM + SVAV + C V + GF + + +
Sbjct: 292 IQEAAF-----TLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGF-GYDMSTPN 345
Query: 353 IPVSHHYYD 361
P+ HYY+
Sbjct: 346 APL--HYYE 352
>gi|28373068 sialyltransferase 6 isoform a [Homo sapiens]
Length = 444
Score = 47.8 bits (112), Expect = 2e-05
Identities = 50/189 (26%), Positives = 80/189 (42%), Gaps = 22/189 (11%)
Query: 185 QCAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSIITLKY 244
+C +VGNGG+L G+ ID D V R N P G KDVGSKT L P ++
Sbjct: 228 RCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKG-FEKDVGSKTTLRITYPE-GAMQR 285
Query: 245 GNLKEKKALFLEDIATYGDAFFL-LPAFSFRANTGTSFKVYYTLEESKARQKVLFFHPKY 303
E+ +LF+ + D +L + R + F K ++ +P +
Sbjct: 286 PEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYF 345
Query: 304 LKDLALFWRTKGVTAYRLSTGLM-------ITSVAVEL----CKNVKLYGFWPFSKTVED 352
+++ A + + GLM + SVAV + C V + GF + + +
Sbjct: 346 IQEAAF-----TLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGF-GYDMSTPN 399
Query: 353 IPVSHHYYD 361
P+ HYY+
Sbjct: 400 APL--HYYE 406
>gi|5454060 sialyltransferase 6 isoform j [Homo sapiens]
Length = 375
Score = 47.8 bits (112), Expect = 2e-05
Identities = 50/189 (26%), Positives = 80/189 (42%), Gaps = 22/189 (11%)
Query: 185 QCAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSIITLKY 244
+C +VGNGG+L G+ ID D V R N P G KDVGSKT L P ++
Sbjct: 159 RCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKG-FEKDVGSKTTLRITYPE-GAMQR 216
Query: 245 GNLKEKKALFLEDIATYGDAFFL-LPAFSFRANTGTSFKVYYTLEESKARQKVLFFHPKY 303
E+ +LF+ + D +L + R + F K ++ +P +
Sbjct: 217 PEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILNPYF 276
Query: 304 LKDLALFWRTKGVTAYRLSTGLM-------ITSVAVEL----CKNVKLYGFWPFSKTVED 352
+++ A + + GLM + SVAV + C V + GF + + +
Sbjct: 277 IQEAAF-----TLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGF-GYDMSTPN 330
Query: 353 IPVSHHYYD 361
P+ HYY+
Sbjct: 331 APL--HYYE 337
>gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform b [Homo sapiens]
Length = 466
Score = 47.4 bits (111), Expect = 2e-05
Identities = 27/56 (48%), Positives = 32/56 (57%), Gaps = 1/56 (1%)
Query: 186 CAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSIIT 241
CAVV + G + S G EID D V R N PT G KDVG+KT + IN I+T
Sbjct: 296 CAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRG-YEKDVGNKTTIRIINSQILT 350
>gi|28373074 sialyltransferase 6 isoform d [Homo sapiens]
Length = 277
Score = 47.0 bits (110), Expect = 3e-05
Identities = 24/48 (50%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
Query: 185 QCAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNL 232
+C +VGNGG+L G+ ID D V R N P G KDVGSKT L
Sbjct: 159 RCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKG-FEKDVGSKTTL 205
>gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [Homo
sapiens]
Length = 329
Score = 45.1 bits (105), Expect = 1e-04
Identities = 63/272 (23%), Positives = 103/272 (37%), Gaps = 51/272 (18%)
Query: 146 TPVGTNMSYEVESKKEIPIKKNIFHMFPVSQPFVDYPYNQCAVVGNGGILNKSLCGTEID 205
TP + Y + +++ ++ + + +C VVGNG L S G I+
Sbjct: 76 TPSAYELPYGTKGSEDLLLRVLAITSSSIPKNIQSLRCRRCVVVGNGHRLRNSSLGDAIN 135
Query: 206 KSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSIITLKYGNLKEKKALFLEDIATYGDAF 265
K D V R N P G DVGSKT + P + A F + D
Sbjct: 136 KYDVVIRLNNAPVAG-YEGDVGSKTTMRLFYP------------ESAHFDPKVENNPDTL 182
Query: 266 FLLPAFSFRANTGTSFKVYYTLEESKARQKVLFF---------HPKYLKDLALFWRTKGV 316
+L AF F T+ K R + F+ +PK ++ L F+ +
Sbjct: 183 LVLVAFK-----AMDFHWIETILSDKKRVRKGFWKQPPLIWDVNPKQIRILNPFFME--I 235
Query: 317 TAYRL---------------STGLMITSVAVELCKNVKLYGF-WPFSKTVEDIPVSHHYY 360
A +L +TGL+ ++A+ LC V + GF +P + + + HYY
Sbjct: 236 AADKLLSLPMQQPRKIKQKPTTGLLAITLALHLCDLVHIAGFGYPDAYNKKQ---TIHYY 292
Query: 361 DN---KLPKHGFHQMPKEYSQILQLHMKGILK 389
+ K H + +E I ++ G +K
Sbjct: 293 EQITLKSMAGSGHNVSQEALAIKRMLEMGAIK 324
>gi|229892273 sialyltransferase 7C isoform 1 [Homo sapiens]
Length = 305
Score = 40.8 bits (94), Expect = 0.002
Identities = 45/189 (23%), Positives = 78/189 (41%), Gaps = 24/189 (12%)
Query: 186 CAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSIITLKYG 245
CA+V N G + G EID+S ++R N PT G +DVG T + ++ + + L
Sbjct: 80 CAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKG-YEEDVGRMTMIRVVSHTSVPLL-- 136
Query: 246 NLKEKKALFLEDIATYGDAFFLLPAFSFRANTGTSFKVYYTLEES-----------KARQ 294
LK F E T + + F G VY L+++ +
Sbjct: 137 -LKNPDYFFKEANTT---IYVIWGPFRNMRKDGNGI-VYNMLKKTVGIYPNAQIYVTTEK 191
Query: 295 KVLFFHPKYLKDLALFWRTKGVTAYRLSTGLMITSVAVELCKNVKLYGFW--PFSKTVED 352
++ + + K+ + + + LSTG +A++ C + +YG + KT
Sbjct: 192 RMSYCDGVFKKETG---KDRVQSGSYLSTGWFTFLLAMDACYGIHVYGMINDTYCKTEGY 248
Query: 353 IPVSHHYYD 361
V +HYY+
Sbjct: 249 RKVPYHYYE 257
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,922,097
Number of Sequences: 37866
Number of extensions: 650006
Number of successful extensions: 1918
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1852
Number of HSP's gapped (non-prelim): 51
length of query: 398
length of database: 18,247,518
effective HSP length: 104
effective length of query: 294
effective length of database: 14,309,454
effective search space: 4206979476
effective search space used: 4206979476
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.