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Search of human proteins with 51896029
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|51896029 annexin A13 isoform b [Homo sapiens]
(357 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|51896029 annexin A13 isoform b [Homo sapiens] 697 0.0
gi|51895795 annexin A13 isoform a [Homo sapiens] 603 e-173
gi|4502111 annexin VII isoform 1 [Homo sapiens] 315 4e-86
gi|4809279 annexin VII isoform 2 [Homo sapiens] 311 6e-85
gi|4502105 annexin IV [Homo sapiens] 291 5e-79
gi|4557317 annexin A11 [Homo sapiens] 291 6e-79
gi|22165433 annexin A11 [Homo sapiens] 291 6e-79
gi|22165431 annexin A11 [Homo sapiens] 291 6e-79
gi|91807122 annexin A8L2 [Homo sapiens] 290 2e-78
gi|91823262 annexin A8 [Homo sapiens] 289 2e-78
gi|149588958 annexin A8-like 1 [Homo sapiens] 288 7e-78
gi|71773415 annexin VI isoform 2 [Homo sapiens] 282 4e-76
gi|71773329 annexin VI isoform 1 [Homo sapiens] 282 4e-76
gi|4502107 annexin 5 [Homo sapiens] 267 1e-71
gi|4826643 annexin A3 [Homo sapiens] 264 1e-70
gi|50845388 annexin A2 isoform 1 [Homo sapiens] 259 2e-69
gi|4757756 annexin A2 isoform 2 [Homo sapiens] 259 3e-69
gi|50845386 annexin A2 isoform 2 [Homo sapiens] 259 3e-69
gi|209862831 annexin A2 isoform 2 [Homo sapiens] 259 3e-69
gi|4502101 annexin I [Homo sapiens] 258 6e-69
gi|48762937 annexin A10 [Homo sapiens] 202 3e-52
gi|145864465 annexin A9 [Homo sapiens] 165 7e-41
gi|239752501 PREDICTED: hypothetical protein XP_002347094 [Homo ... 103 2e-22
gi|150170670 piccolo isoform 2 [Homo sapiens] 37 0.021
gi|150378539 piccolo isoform 1 [Homo sapiens] 37 0.021
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 33 0.30
gi|62821787 COBL-like 1 [Homo sapiens] 33 0.39
gi|148806902 TBC1 domain family, member 12 [Homo sapiens] 33 0.51
gi|22035569 GC-rich sequence DNA-binding factor candidate isofor... 32 0.67
gi|22035565 GC-rich sequence DNA-binding factor candidate isofor... 32 0.67
>gi|51896029 annexin A13 isoform b [Homo sapiens]
Length = 357
Score = 697 bits (1800), Expect = 0.0
Identities = 357/357 (100%), Positives = 357/357 (100%)
Query: 1 MGNRHSQSYTLSEGSQQLPKGDSQPSTVVQPLSHPSRNGEPEAPQPAKASSPQGFDVDRD 60
MGNRHSQSYTLSEGSQQLPKGDSQPSTVVQPLSHPSRNGEPEAPQPAKASSPQGFDVDRD
Sbjct: 1 MGNRHSQSYTLSEGSQQLPKGDSQPSTVVQPLSHPSRNGEPEAPQPAKASSPQGFDVDRD 60
Query: 61 AKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELSGNFEKT 120
AKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELSGNFEKT
Sbjct: 61 AKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELSGNFEKT 120
Query: 121 ALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLESD 180
ALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLESD
Sbjct: 121 ALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLESD 180
Query: 181 VKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAK 240
VKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAK
Sbjct: 181 VKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAK 240
Query: 241 RSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAERLYKSMK 300
RSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAERLYKSMK
Sbjct: 241 RSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAERLYKSMK 300
Query: 301 GAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVALLH 357
GAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVALLH
Sbjct: 301 GAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVALLH 357
>gi|51895795 annexin A13 isoform a [Homo sapiens]
Length = 316
Score = 603 bits (1555), Expect = e-173
Identities = 311/311 (100%), Positives = 311/311 (100%)
Query: 47 AKASSPQGFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELE 106
AKASSPQGFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELE
Sbjct: 6 AKASSPQGFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELE 65
Query: 107 EVLKSELSGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIK 166
EVLKSELSGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIK
Sbjct: 66 EVLKSELSGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIK 125
Query: 167 EAYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGR 226
EAYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGR
Sbjct: 126 EAYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGR 185
Query: 227 WGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQD 286
WGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQD
Sbjct: 186 WGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQD 245
Query: 287 CEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSG 346
CEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSG
Sbjct: 246 CEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSG 305
Query: 347 DFRKLLVALLH 357
DFRKLLVALLH
Sbjct: 306 DFRKLLVALLH 316
>gi|4502111 annexin VII isoform 1 [Homo sapiens]
Length = 466
Score = 315 bits (807), Expect = 4e-86
Identities = 173/360 (48%), Positives = 240/360 (66%), Gaps = 14/360 (3%)
Query: 6 SQSYTLSEGSQQLPKGDSQPSTVVQPLSHPSRNGEPEAP-QPAKASS-PQG-------FD 56
SQSY G Q+P P + P +P G+P P QPA + QG FD
Sbjct: 110 SQSY--GGGPAQVPLPGGFPGGQM-PSQYPG--GQPTYPSQPATVTQVTQGTIRPAANFD 164
Query: 57 VDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELSGN 116
RDA+ L KA KG GT+E AI+++++ R++D+RQ+IK +K +YGK+L + LKSELSGN
Sbjct: 165 AIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLKSELSGN 224
Query: 117 FEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRS 176
E+ LAL P+ Y A L+KAM+G GT E VLIE+LCTRTN+EI I YQ F R
Sbjct: 225 MEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFGRD 284
Query: 177 LESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNE 236
LE D++ DTSG+ +++LVS+ Q NR+E ++ +A +DA+ LY AGEGR GTDE FN
Sbjct: 285 LEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQRLYQAGEGRLGTDESCFNM 344
Query: 237 VLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAERLY 296
+LA RS+ QLRAT +AY + +D+ ++ E SG ++ T+++CA + +FAERLY
Sbjct: 345 ILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAFFAERLY 404
Query: 297 KSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVALL 356
+MKGAGTD+ TL+RIVVTR+E+DL IK F + YQK+L M+ DTSGD+R+LL+A++
Sbjct: 405 YAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTSGDYRRLLLAIV 464
>gi|4809279 annexin VII isoform 2 [Homo sapiens]
Length = 488
Score = 311 bits (797), Expect = 6e-85
Identities = 155/302 (51%), Positives = 217/302 (71%)
Query: 55 FDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELS 114
FD RDA+ L KA KG GT+E AI+++++ R++D+RQ+IK +K +YGK+L + LKSELS
Sbjct: 185 FDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLKSELS 244
Query: 115 GNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFD 174
GN E+ LAL P+ Y A L+KAM+G GT E VLIE+LCTRTN+EI I YQ F
Sbjct: 245 GNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFG 304
Query: 175 RSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAF 234
R LE D++ DTSG+ +++LVS+ Q NR+E ++ +A +DA+ LY AGEGR GTDE F
Sbjct: 305 RDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQRLYQAGEGRLGTDESCF 364
Query: 235 NEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAER 294
N +LA RS+ QLRAT +AY + +D+ ++ E SG ++ T+++CA + +FAER
Sbjct: 365 NMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAFFAER 424
Query: 295 LYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVA 354
LY +MKGAGTD+ TL+RIVVTR+E+DL IK F + YQK+L M+ DTSGD+R+LL+A
Sbjct: 425 LYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTSGDYRRLLLA 484
Query: 355 LL 356
++
Sbjct: 485 IV 486
>gi|4502105 annexin IV [Homo sapiens]
Length = 321
Score = 291 bits (746), Expect = 5e-79
Identities = 149/308 (48%), Positives = 215/308 (69%), Gaps = 2/308 (0%)
Query: 48 KASSPQGFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEE 107
KA+S GF+ DA+ L KA KG+GT+E AII +L+ R + +RQ+I+ YK+T G++L +
Sbjct: 11 KAAS--GFNAMEDAQTLRKAMKGLGTDEDAIISVLAYRNTAQRQEIRTAYKSTIGRDLID 68
Query: 108 VLKSELSGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKE 167
LKSELSGNFE+ + ++ Y ++L++AMKG GTDE LIE+L +RT +EI I +
Sbjct: 69 DLKSELSGNFEQVIVGMMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRTPEEIRRISQ 128
Query: 168 AYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRW 227
YQ+ + RSLE D++ DTS +++LVSL R+EG+ +D L QDA+DLY+AGE +W
Sbjct: 129 TYQQQYGRSLEDDIRSDTSFMFQRVLVSLSAGGRDEGNYLDDALVRQDAQDLYEAGEKKW 188
Query: 228 GTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDC 287
GTDE+ F VL R+ L F Y+ + KDIE++I+ ETSG + A L +V+C ++
Sbjct: 189 GTDEVKFLTVLCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLAIVKCMRNK 248
Query: 288 EDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGD 347
YFAE+LYKSMKG GTD+ TLIR++V+RAE+D+ I+A F+ Y KSL ++ DTSGD
Sbjct: 249 SAYFAEKLYKSMKGLGTDDNTLIRVMVSRAEIDMLDIRAHFKRLYGKSLYSFIKGDTSGD 308
Query: 348 FRKLLVAL 355
+RK+L+ L
Sbjct: 309 YRKVLLVL 316
Score = 103 bits (258), Expect = 2e-22
Identities = 71/233 (30%), Positives = 120/233 (51%), Gaps = 21/233 (9%)
Query: 133 ARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKI 192
A+ L+KAMKGLGTDE +I VL R + I+ AY+ R L D+K + SGN +++
Sbjct: 22 AQTLRKAMKGLGTDEDAIISVLAYRNTAQRQEIRTAYKSTIGRDLIDDLKSELSGNFEQV 81
Query: 193 LVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQA 252
+V ++ D ++L A +G GTDE E+LA R+ +++R Q
Sbjct: 82 IVGMMTPT-----------VLYDVQELRRAMKGA-GTDEGCLIEILASRTPEEIRRISQT 129
Query: 253 YQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYF--------AERLYKS-MKGAG 303
YQ G+ +E+ I +TS Q+ ++L +D +Y A+ LY++ K G
Sbjct: 130 YQQQYGRSLEDDIRSDTSFMFQRVLVSLSAGGRDEGNYLDDALVRQDAQDLYEAGEKKWG 189
Query: 304 TDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVALL 356
TDE + ++ +R L + +++ QK + ++S+TSG F L+A++
Sbjct: 190 TDEVKFLTVLCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLAIV 242
>gi|4557317 annexin A11 [Homo sapiens]
Length = 505
Score = 291 bits (745), Expect = 6e-79
Identities = 155/335 (46%), Positives = 222/335 (66%), Gaps = 9/335 (2%)
Query: 21 GDSQPSTVVQPLSHPSRNGEPEAPQPAKASSPQGFDVDRDAKKLNKACKGMGTNEAAIIE 80
G + V P SR +AP GFD RDA+ L KA KG GT+E AII+
Sbjct: 175 GSGTVTPAVPPTQFGSRGTITDAP---------GFDPLRDAEVLRKAMKGFGTDEQAIID 225
Query: 81 ILSGRTSDERQQIKQKYKATYGKELEEVLKSELSGNFEKTALALLDRPSEYAARQLQKAM 140
L R++ +RQQI +K YGK+L + LKSELSGNFEKT LAL+ P + ++++A+
Sbjct: 226 CLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAI 285
Query: 141 KGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQAN 200
KG+GTDE+ LIE+L +R+N+ I + AY+ F ++LE ++ DTSG+ +++L+SL Q N
Sbjct: 286 KGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGN 345
Query: 201 RNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKD 260
R+E +VD LA +DA++LY AGE R GTDE FN VL RS L A F YQ + G+D
Sbjct: 346 RDESTNVDMSLAQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRD 405
Query: 261 IEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVD 320
IE++I E SGDL++ L +V+C ++ +FAERL K+M+GAGT + TLIRI+V+R+E D
Sbjct: 406 IEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETD 465
Query: 321 LQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVAL 355
L I+++++ Y KSL + DTSGD+RK+L+ +
Sbjct: 466 LLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLKI 500
Score = 86.3 bits (212), Expect = 4e-17
Identities = 46/146 (31%), Positives = 87/146 (59%), Gaps = 4/146 (2%)
Query: 59 RDAKKLNKACKG-MGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELSGNF 117
RDA++L A + +GT+E+ +L R+ + +Y+ G+++E+ + E+SG+
Sbjct: 359 RDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDL 418
Query: 118 EKTALAL---LDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFD 174
E+ LA+ L + A +L KAM+G GT + LI ++ +R+ +++ I+ Y+R++
Sbjct: 419 EEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYG 478
Query: 175 RSLESDVKGDTSGNLKKILVSLLQAN 200
+SL D+ GDTSG+ +KIL+ + N
Sbjct: 479 KSLYHDISGDTSGDYRKILLKICGGN 504
Score = 48.9 bits (115), Expect = 7e-06
Identities = 26/65 (40%), Positives = 40/65 (61%)
Query: 292 AERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKL 351
AE L K+MKG GTDE+ +I + +R+ Q I F+ Y K L ++S+ SG+F K
Sbjct: 206 AEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKT 265
Query: 352 LVALL 356
++AL+
Sbjct: 266 ILALM 270
>gi|22165433 annexin A11 [Homo sapiens]
Length = 505
Score = 291 bits (745), Expect = 6e-79
Identities = 155/335 (46%), Positives = 222/335 (66%), Gaps = 9/335 (2%)
Query: 21 GDSQPSTVVQPLSHPSRNGEPEAPQPAKASSPQGFDVDRDAKKLNKACKGMGTNEAAIIE 80
G + V P SR +AP GFD RDA+ L KA KG GT+E AII+
Sbjct: 175 GSGTVTPAVPPTQFGSRGTITDAP---------GFDPLRDAEVLRKAMKGFGTDEQAIID 225
Query: 81 ILSGRTSDERQQIKQKYKATYGKELEEVLKSELSGNFEKTALALLDRPSEYAARQLQKAM 140
L R++ +RQQI +K YGK+L + LKSELSGNFEKT LAL+ P + ++++A+
Sbjct: 226 CLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAI 285
Query: 141 KGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQAN 200
KG+GTDE+ LIE+L +R+N+ I + AY+ F ++LE ++ DTSG+ +++L+SL Q N
Sbjct: 286 KGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGN 345
Query: 201 RNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKD 260
R+E +VD LA +DA++LY AGE R GTDE FN VL RS L A F YQ + G+D
Sbjct: 346 RDESTNVDMSLAQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRD 405
Query: 261 IEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVD 320
IE++I E SGDL++ L +V+C ++ +FAERL K+M+GAGT + TLIRI+V+R+E D
Sbjct: 406 IEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETD 465
Query: 321 LQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVAL 355
L I+++++ Y KSL + DTSGD+RK+L+ +
Sbjct: 466 LLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLKI 500
Score = 86.3 bits (212), Expect = 4e-17
Identities = 46/146 (31%), Positives = 87/146 (59%), Gaps = 4/146 (2%)
Query: 59 RDAKKLNKACKG-MGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELSGNF 117
RDA++L A + +GT+E+ +L R+ + +Y+ G+++E+ + E+SG+
Sbjct: 359 RDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDL 418
Query: 118 EKTALAL---LDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFD 174
E+ LA+ L + A +L KAM+G GT + LI ++ +R+ +++ I+ Y+R++
Sbjct: 419 EEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYG 478
Query: 175 RSLESDVKGDTSGNLKKILVSLLQAN 200
+SL D+ GDTSG+ +KIL+ + N
Sbjct: 479 KSLYHDISGDTSGDYRKILLKICGGN 504
Score = 48.9 bits (115), Expect = 7e-06
Identities = 26/65 (40%), Positives = 40/65 (61%)
Query: 292 AERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKL 351
AE L K+MKG GTDE+ +I + +R+ Q I F+ Y K L ++S+ SG+F K
Sbjct: 206 AEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKT 265
Query: 352 LVALL 356
++AL+
Sbjct: 266 ILALM 270
>gi|22165431 annexin A11 [Homo sapiens]
Length = 505
Score = 291 bits (745), Expect = 6e-79
Identities = 155/335 (46%), Positives = 222/335 (66%), Gaps = 9/335 (2%)
Query: 21 GDSQPSTVVQPLSHPSRNGEPEAPQPAKASSPQGFDVDRDAKKLNKACKGMGTNEAAIIE 80
G + V P SR +AP GFD RDA+ L KA KG GT+E AII+
Sbjct: 175 GSGTVTPAVPPTQFGSRGTITDAP---------GFDPLRDAEVLRKAMKGFGTDEQAIID 225
Query: 81 ILSGRTSDERQQIKQKYKATYGKELEEVLKSELSGNFEKTALALLDRPSEYAARQLQKAM 140
L R++ +RQQI +K YGK+L + LKSELSGNFEKT LAL+ P + ++++A+
Sbjct: 226 CLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAI 285
Query: 141 KGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQAN 200
KG+GTDE+ LIE+L +R+N+ I + AY+ F ++LE ++ DTSG+ +++L+SL Q N
Sbjct: 286 KGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGN 345
Query: 201 RNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKD 260
R+E +VD LA +DA++LY AGE R GTDE FN VL RS L A F YQ + G+D
Sbjct: 346 RDESTNVDMSLAQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRD 405
Query: 261 IEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVD 320
IE++I E SGDL++ L +V+C ++ +FAERL K+M+GAGT + TLIRI+V+R+E D
Sbjct: 406 IEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETD 465
Query: 321 LQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVAL 355
L I+++++ Y KSL + DTSGD+RK+L+ +
Sbjct: 466 LLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLKI 500
Score = 86.3 bits (212), Expect = 4e-17
Identities = 46/146 (31%), Positives = 87/146 (59%), Gaps = 4/146 (2%)
Query: 59 RDAKKLNKACKG-MGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELSGNF 117
RDA++L A + +GT+E+ +L R+ + +Y+ G+++E+ + E+SG+
Sbjct: 359 RDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDL 418
Query: 118 EKTALAL---LDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFD 174
E+ LA+ L + A +L KAM+G GT + LI ++ +R+ +++ I+ Y+R++
Sbjct: 419 EEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYG 478
Query: 175 RSLESDVKGDTSGNLKKILVSLLQAN 200
+SL D+ GDTSG+ +KIL+ + N
Sbjct: 479 KSLYHDISGDTSGDYRKILLKICGGN 504
Score = 48.9 bits (115), Expect = 7e-06
Identities = 26/65 (40%), Positives = 40/65 (61%)
Query: 292 AERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKL 351
AE L K+MKG GTDE+ +I + +R+ Q I F+ Y K L ++S+ SG+F K
Sbjct: 206 AEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKT 265
Query: 352 LVALL 356
++AL+
Sbjct: 266 ILALM 270
>gi|91807122 annexin A8L2 [Homo sapiens]
Length = 327
Score = 290 bits (741), Expect = 2e-78
Identities = 152/307 (49%), Positives = 214/307 (69%), Gaps = 1/307 (0%)
Query: 51 SPQGFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLK 110
S F+ D DA+ L KA KG+GTNE AII++L+ R++ +RQQI + +KA +GK+L E LK
Sbjct: 17 SSSHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTETLK 76
Query: 111 SELSGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQ 170
SELSG FE+ +AL+ P Y A++L AMKGLGT E V+IE+L +RT ++ I +AY+
Sbjct: 77 SELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMKAYE 136
Query: 171 RLFDRSLESDVKGDTSGNLKKILVSLLQANRNE-GDDVDKDLAGQDAKDLYDAGEGRWGT 229
+ SLE D++ DTSG L++ILV LLQ +R++ VD LA QDA+DLY AGE GT
Sbjct: 137 EDYGSSLEEDIQADTSGYLERILVCLLQGSRDDVSSFVDPALALQDAQDLYAAGENIRGT 196
Query: 230 DELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCED 289
DE+ F +L RS L F+ Y+ + K IE++I+ ET G L++A LT+V+C Q+
Sbjct: 197 DEMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHS 256
Query: 290 YFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFR 349
YFAERLY +MKGAGT + TLIR +V+R+E+DL IK F++ Y K+LS M+ DTSGD++
Sbjct: 257 YFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMIMEDTSGDYK 316
Query: 350 KLLVALL 356
L++L+
Sbjct: 317 NALLSLV 323
Score = 58.9 bits (141), Expect = 7e-09
Identities = 26/66 (39%), Positives = 45/66 (68%)
Query: 292 AERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKL 351
AE LYK+MKG GT+E+ +I ++ R+ Q I F+ ++ K L++ ++S+ SG F +L
Sbjct: 27 AETLYKAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTETLKSELSGKFERL 86
Query: 352 LVALLH 357
+VAL++
Sbjct: 87 IVALMY 92
>gi|91823262 annexin A8 [Homo sapiens]
Length = 327
Score = 289 bits (740), Expect = 2e-78
Identities = 152/307 (49%), Positives = 214/307 (69%), Gaps = 1/307 (0%)
Query: 51 SPQGFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLK 110
S F+ D DA+ L KA KG+GTNE AII++L+ R++ +RQQI + +KA +GK+L E LK
Sbjct: 17 SSSHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTETLK 76
Query: 111 SELSGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQ 170
SELSG FE+ +AL+ P Y A++L AMKGLGT E V+IE+L +RT ++ I +AY+
Sbjct: 77 SELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMKAYE 136
Query: 171 RLFDRSLESDVKGDTSGNLKKILVSLLQANRNE-GDDVDKDLAGQDAKDLYDAGEGRWGT 229
+ SLE D++ DTSG L++ILV LLQ +R++ VD LA QDA+DLY AGE GT
Sbjct: 137 EDYGSSLEEDIQADTSGYLERILVCLLQGSRDDVSSFVDPGLALQDAQDLYAAGEKIRGT 196
Query: 230 DELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCED 289
DE+ F +L RS L F+ Y+ + K IE++I+ ET G L++A LT+V+C Q+
Sbjct: 197 DEMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHS 256
Query: 290 YFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFR 349
YFAERLY +MKGAGT + TLIR +V+R+E+DL IK F++ Y K+LS M+ DTSGD++
Sbjct: 257 YFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMIMEDTSGDYK 316
Query: 350 KLLVALL 356
L++L+
Sbjct: 317 NALLSLV 323
Score = 58.9 bits (141), Expect = 7e-09
Identities = 26/66 (39%), Positives = 45/66 (68%)
Query: 292 AERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKL 351
AE LYK+MKG GT+E+ +I ++ R+ Q I F+ ++ K L++ ++S+ SG F +L
Sbjct: 27 AETLYKAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTETLKSELSGKFERL 86
Query: 352 LVALLH 357
+VAL++
Sbjct: 87 IVALMY 92
>gi|149588958 annexin A8-like 1 [Homo sapiens]
Length = 327
Score = 288 bits (736), Expect = 7e-78
Identities = 151/307 (49%), Positives = 214/307 (69%), Gaps = 1/307 (0%)
Query: 51 SPQGFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLK 110
S F+ D DA+ L +A KG+GTNE AII++L+ R++ +RQQI + +KA +GK+L E LK
Sbjct: 17 SSSHFNPDPDAETLYQAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTETLK 76
Query: 111 SELSGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQ 170
SELSG FE+ +AL+ P Y A++L AMKGLGT E V+IE+L +RT ++ I +AY+
Sbjct: 77 SELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMKAYE 136
Query: 171 RLFDRSLESDVKGDTSGNLKKILVSLLQANRNE-GDDVDKDLAGQDAKDLYDAGEGRWGT 229
+ SLE D++ DTSG L++ILV LLQ +R++ VD LA QDA+DLY AGE GT
Sbjct: 137 EDYGSSLEEDIQADTSGYLERILVCLLQGSRDDVSSFVDPGLALQDAQDLYAAGEKIRGT 196
Query: 230 DELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCED 289
DE+ F +L RS L F+ Y+ + K IE++I+ ET G L++A LT+V+C Q+
Sbjct: 197 DEMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHS 256
Query: 290 YFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFR 349
YFAERLY +MKGAGT + TLIR +V+R+E+DL IK F++ Y K+LS M+ DTSGD++
Sbjct: 257 YFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMIMEDTSGDYK 316
Query: 350 KLLVALL 356
L++L+
Sbjct: 317 NALLSLV 323
Score = 57.4 bits (137), Expect = 2e-08
Identities = 25/66 (37%), Positives = 45/66 (68%)
Query: 292 AERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKL 351
AE LY++MKG GT+E+ +I ++ R+ Q I F+ ++ K L++ ++S+ SG F +L
Sbjct: 27 AETLYQAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTETLKSELSGKFERL 86
Query: 352 LVALLH 357
+VAL++
Sbjct: 87 IVALMY 92
>gi|71773415 annexin VI isoform 2 [Homo sapiens]
Length = 667
Score = 282 bits (721), Expect = 4e-76
Identities = 139/302 (46%), Positives = 211/302 (69%)
Query: 54 GFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSEL 113
GFD ++DA+ L A KG G+++ AI++I++ R++ +RQ++ Q YK+ YGK+L LK EL
Sbjct: 19 GFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIADLKYEL 78
Query: 114 SGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLF 173
+G FE+ + L+ P+ A++++ A+ G+GTDE LIE+L +RTN+++ + AY+ +
Sbjct: 79 TGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQLVAAYKDAY 138
Query: 174 DRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELA 233
+R LE+D+ GDTSG+ +K+LV LLQ R E D V +DL QD +DLY+AGE +WGTDE
Sbjct: 139 ERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGELKWGTDEAQ 198
Query: 234 FNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAE 293
F +L RS + LR F Y GK IE +I E SGD +K L +V+C + +YFAE
Sbjct: 199 FIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRSTPEYFAE 258
Query: 294 RLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLV 353
RL+K+MKG GT + TLIRI+V+R+E+D+ I+ F+ KY+KSL M+++DTSG+++K L+
Sbjct: 259 RLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSGEYKKTLL 318
Query: 354 AL 355
L
Sbjct: 319 KL 320
Score = 270 bits (689), Expect = 2e-72
Identities = 141/301 (46%), Positives = 207/301 (68%), Gaps = 1/301 (0%)
Query: 55 FDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELS 114
F+ D DAK L KA KG+GT+E II+I++ R++ +RQQI+Q +K+ +G++L LKSE+S
Sbjct: 363 FNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSEIS 422
Query: 115 GNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFD 174
G+ + L L+ P+ Y A+QL+KAM+G GTDE LIE+L TRTN EI AI EAY+ +
Sbjct: 423 GDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKEDYH 482
Query: 175 RSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAF 234
+SLE + DTSG+ ++IL+SL +R EG + + D A +DA+++ D G + E F
Sbjct: 483 KSLEDALSSDTSGHFRRILISLATGHREEGGE-NLDQAREDAQEIADTPSGDKTSLETRF 541
Query: 235 NEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAER 294
+L RSY LR FQ + + D+E I++E SGD++ A++ +V+ ++ +FA++
Sbjct: 542 MTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIVQSVKNKPLFFADK 601
Query: 295 LYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVA 354
LYKSMKGAGTDE+TL RI+V+R+E+DL I+ +F EKY KSL + DTSGDF K L+A
Sbjct: 602 LYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIEGDTSGDFLKALLA 661
Query: 355 L 355
L
Sbjct: 662 L 662
Score = 124 bits (311), Expect = 1e-28
Identities = 98/357 (27%), Positives = 170/357 (47%), Gaps = 69/357 (19%)
Query: 50 SSPQGFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVL 109
S+P+ F A++L KA KG+GT + +I I+ R+ + I++ ++ Y K L ++
Sbjct: 251 STPEYF-----AERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMI 305
Query: 110 KSELSGNFEKTALALLDRPSEYA------------------------------------- 132
K++ SG ++KT L L + A
Sbjct: 306 KNDTSGEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRPANDFNP 365
Query: 133 ---ARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNL 189
A+ L+KAMKGLGTDE +I+++ R+N + I++ ++ F R L +D+K + SG+L
Sbjct: 366 DADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSEISGDL 425
Query: 190 KKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRAT 249
++++ L+ A DAK L A EG GTDE A E+LA R+ ++RA
Sbjct: 426 ARLILGLMMPP-----------AHYDAKQLKKAMEGA-GTDEKALIEILATRTNAEIRAI 473
Query: 250 FQAYQILIGKDIEEAIEEETSGDLQKAYLTLV---------RCAQDCEDYFAERLYKSMK 300
+AY+ K +E+A+ +TSG ++ ++L Q ED A+ + +
Sbjct: 474 NEAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEGGENLDQARED--AQEIADTPS 531
Query: 301 GAGTDEET-LIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVALL 356
G T ET + I+ TR+ L+ + +F + + ++ + SGD R VA++
Sbjct: 532 GDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIV 588
Score = 100 bits (248), Expect = 3e-21
Identities = 66/234 (28%), Positives = 127/234 (54%), Gaps = 23/234 (9%)
Query: 133 ARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKI 192
A L AMKG G+D+ +++++ +R+N++ + ++Y+ L+ + L +D+K + +G +++
Sbjct: 26 AEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIADLKYELTGKFERL 85
Query: 193 LVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQA 252
+V L++ A DAK++ DA G GTDE E+LA R+ +Q+ A
Sbjct: 86 IVGLMRPP-----------AYCDAKEIKDAISGI-GTDEKCLIEILASRTNEQMHQLVAA 133
Query: 253 YQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAERLYKS----------MKGA 302
Y+ +D+E I +TSG QK + L++ ++ +D +E L + +K
Sbjct: 134 YKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGELKW- 192
Query: 303 GTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVALL 356
GTDE I I+ R++ L+ + ++ + K + +R + SGDF KL++A++
Sbjct: 193 GTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVV 246
Score = 84.3 bits (207), Expect = 1e-16
Identities = 47/143 (32%), Positives = 85/143 (59%), Gaps = 4/143 (2%)
Query: 214 QDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDL 273
QDA+ LY A +G +G+D+ A +++ RS +Q + Q+Y+ L GKD+ ++ E +G
Sbjct: 24 QDAEALYTAMKG-FGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIADLKYELTGKF 82
Query: 274 QKAYLTLVRCAQDCEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQ 333
++ + L+R C+ A+ + ++ G GTDE+ LI I+ +R + + A +++ Y+
Sbjct: 83 ERLIVGLMRPPAYCD---AKEIKDAISGIGTDEKCLIEILASRTNEQMHQLVAAYKDAYE 139
Query: 334 KSLSDMVRSDTSGDFRKLLVALL 356
+ L + DTSG F+K+LV LL
Sbjct: 140 RDLEADIIGDTSGHFQKMLVVLL 162
>gi|71773329 annexin VI isoform 1 [Homo sapiens]
Length = 673
Score = 282 bits (721), Expect = 4e-76
Identities = 139/302 (46%), Positives = 211/302 (69%)
Query: 54 GFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSEL 113
GFD ++DA+ L A KG G+++ AI++I++ R++ +RQ++ Q YK+ YGK+L LK EL
Sbjct: 19 GFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIADLKYEL 78
Query: 114 SGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLF 173
+G FE+ + L+ P+ A++++ A+ G+GTDE LIE+L +RTN+++ + AY+ +
Sbjct: 79 TGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQLVAAYKDAY 138
Query: 174 DRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELA 233
+R LE+D+ GDTSG+ +K+LV LLQ R E D V +DL QD +DLY+AGE +WGTDE
Sbjct: 139 ERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGELKWGTDEAQ 198
Query: 234 FNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAE 293
F +L RS + LR F Y GK IE +I E SGD +K L +V+C + +YFAE
Sbjct: 199 FIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRSTPEYFAE 258
Query: 294 RLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLV 353
RL+K+MKG GT + TLIRI+V+R+E+D+ I+ F+ KY+KSL M+++DTSG+++K L+
Sbjct: 259 RLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSGEYKKTLL 318
Query: 354 AL 355
L
Sbjct: 319 KL 320
Score = 263 bits (672), Expect = 2e-70
Identities = 141/307 (45%), Positives = 207/307 (67%), Gaps = 7/307 (2%)
Query: 55 FDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELS 114
F+ D DAK L KA KG+GT+E II+I++ R++ +RQQI+Q +K+ +G++L LKSE+S
Sbjct: 363 FNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSEIS 422
Query: 115 GNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFD 174
G+ + L L+ P+ Y A+QL+KAM+G GTDE LIE+L TRTN EI AI EAY+ +
Sbjct: 423 GDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKEDYH 482
Query: 175 RSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAK------DLYDAGEGRWG 228
+SLE + DTSG+ ++IL+SL +R EG + + D A +DA+ ++ D G
Sbjct: 483 KSLEDALSSDTSGHFRRILISLATGHREEGGE-NLDQAREDAQVAAEILEIADTPSGDKT 541
Query: 229 TDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCE 288
+ E F +L RSY LR FQ + + D+E I++E SGD++ A++ +V+ ++
Sbjct: 542 SLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIVQSVKNKP 601
Query: 289 DYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDF 348
+FA++LYKSMKGAGTDE+TL RI+V+R+E+DL I+ +F EKY KSL + DTSGDF
Sbjct: 602 LFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIEGDTSGDF 661
Query: 349 RKLLVAL 355
K L+AL
Sbjct: 662 LKALLAL 668
Score = 120 bits (300), Expect = 2e-27
Identities = 97/361 (26%), Positives = 170/361 (47%), Gaps = 71/361 (19%)
Query: 50 SSPQGFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVL 109
S+P+ F A++L KA KG+GT + +I I+ R+ + I++ ++ Y K L ++
Sbjct: 251 STPEYF-----AERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMI 305
Query: 110 KSELSGNFEKTALALLDRPSEYA------------------------------------- 132
K++ SG ++KT L L + A
Sbjct: 306 KNDTSGEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRPANDFNP 365
Query: 133 ---ARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNL 189
A+ L+KAMKGLGTDE +I+++ R+N + I++ ++ F R L +D+K + SG+L
Sbjct: 366 DADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSEISGDL 425
Query: 190 KKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRAT 249
++++ L+ A DAK L A EG GTDE A E+LA R+ ++RA
Sbjct: 426 ARLILGLMMPP-----------AHYDAKQLKKAMEGA-GTDEKALIEILATRTNAEIRAI 473
Query: 250 FQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRC-----------AQDCEDYFAE--RLY 296
+AY+ K +E+A+ +TSG ++ ++L A++ AE +
Sbjct: 474 NEAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEGGENLDQAREDAQVAAEILEIA 533
Query: 297 KSMKGAGTDEET-LIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVAL 355
+ G T ET + I+ TR+ L+ + +F + + ++ + SGD R VA+
Sbjct: 534 DTPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAI 593
Query: 356 L 356
+
Sbjct: 594 V 594
Score = 100 bits (248), Expect = 3e-21
Identities = 66/234 (28%), Positives = 127/234 (54%), Gaps = 23/234 (9%)
Query: 133 ARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKI 192
A L AMKG G+D+ +++++ +R+N++ + ++Y+ L+ + L +D+K + +G +++
Sbjct: 26 AEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIADLKYELTGKFERL 85
Query: 193 LVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQA 252
+V L++ A DAK++ DA G GTDE E+LA R+ +Q+ A
Sbjct: 86 IVGLMRPP-----------AYCDAKEIKDAISGI-GTDEKCLIEILASRTNEQMHQLVAA 133
Query: 253 YQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAERLYKS----------MKGA 302
Y+ +D+E I +TSG QK + L++ ++ +D +E L + +K
Sbjct: 134 YKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGELKW- 192
Query: 303 GTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVALL 356
GTDE I I+ R++ L+ + ++ + K + +R + SGDF KL++A++
Sbjct: 193 GTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVV 246
Score = 84.3 bits (207), Expect = 1e-16
Identities = 47/143 (32%), Positives = 85/143 (59%), Gaps = 4/143 (2%)
Query: 214 QDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDL 273
QDA+ LY A +G +G+D+ A +++ RS +Q + Q+Y+ L GKD+ ++ E +G
Sbjct: 24 QDAEALYTAMKG-FGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIADLKYELTGKF 82
Query: 274 QKAYLTLVRCAQDCEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQ 333
++ + L+R C+ A+ + ++ G GTDE+ LI I+ +R + + A +++ Y+
Sbjct: 83 ERLIVGLMRPPAYCD---AKEIKDAISGIGTDEKCLIEILASRTNEQMHQLVAAYKDAYE 139
Query: 334 KSLSDMVRSDTSGDFRKLLVALL 356
+ L + DTSG F+K+LV LL
Sbjct: 140 RDLEADIIGDTSGHFQKMLVVLL 162
>gi|4502107 annexin 5 [Homo sapiens]
Length = 320
Score = 267 bits (682), Expect = 1e-71
Identities = 136/302 (45%), Positives = 202/302 (66%)
Query: 54 GFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSEL 113
GFD DA+ L KA KG+GT+E +I+ +L+ R++ +RQ+I +K +G++L + LKSEL
Sbjct: 14 GFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLKSEL 73
Query: 114 SGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLF 173
+G FEK +AL+ Y A +L+ A+KG GT+E VL E++ +RT +E+ AIK+ Y+ +
Sbjct: 74 TGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEY 133
Query: 174 DRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELA 233
SLE DV GDTSG +++LV LLQANR+ +D+ QDA+ L+ AGE +WGTDE
Sbjct: 134 GSSLEDDVVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGELKWGTDEEK 193
Query: 234 FNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAE 293
F + RS LR F Y + G IEE I+ ETSG+L++ L +V+ + Y AE
Sbjct: 194 FITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAE 253
Query: 294 RLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLV 353
LY +MKGAGTD+ TLIR++V+R+E+DL I+ +F++ + SL M++ DTSGD++K L+
Sbjct: 254 TLYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALL 313
Query: 354 AL 355
L
Sbjct: 314 LL 315
Score = 103 bits (258), Expect = 2e-22
Identities = 71/233 (30%), Positives = 128/233 (54%), Gaps = 21/233 (9%)
Query: 133 ARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKI 192
A L+KAMKGLGTDE ++ +L +R+N + I A++ LF R L D+K + +G +K+
Sbjct: 21 AETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLKSELTGKFEKL 80
Query: 193 LVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQA 252
+V+L++ +R DA +L A +G GT+E E++A R+ ++LRA Q
Sbjct: 81 IVALMKPSRL-----------YDAYELKHALKGA-GTNEKVLTEIIASRTPEELRAIKQV 128
Query: 253 YQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCE--------DYFAERLYKSMKGA-G 303
Y+ G +E+ + +TSG Q+ + L++ +D + + A+ L+++ + G
Sbjct: 129 YEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGELKWG 188
Query: 304 TDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVALL 356
TDEE I I TR+ L+ + K+ + + + +TSG+ +LL+A++
Sbjct: 189 TDEEKFITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAVV 241
Score = 82.0 bits (201), Expect = 7e-16
Identities = 50/142 (35%), Positives = 84/142 (59%), Gaps = 4/142 (2%)
Query: 215 DAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQ 274
DA+ L A +G GTDE + +L RS Q + A++ L G+D+ + ++ E +G +
Sbjct: 20 DAETLRKAMKGL-GTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLKSELTGKFE 78
Query: 275 KAYLTLVRCAQDCEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQK 334
K + L++ ++ Y A L ++KGAGT+E+ L I+ +R +L+ IK ++E+Y
Sbjct: 79 KLIVALMKPSRL---YDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYGS 135
Query: 335 SLSDMVRSDTSGDFRKLLVALL 356
SL D V DTSG ++++LV LL
Sbjct: 136 SLEDDVVGDTSGYYQRMLVVLL 157
>gi|4826643 annexin A3 [Homo sapiens]
Length = 323
Score = 264 bits (674), Expect = 1e-70
Identities = 133/301 (44%), Positives = 206/301 (68%)
Query: 55 FDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELS 114
F DA+ + KA +G+GT+E +I IL+ R++ +RQ I ++Y+A YGKEL++ LK +LS
Sbjct: 18 FSPSVDAEAIQKAIRGIGTDEKMLISILTERSNAQRQLIVKEYQAAYGKELKDDLKGDLS 77
Query: 115 GNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFD 174
G+FE +AL+ P+ + A+QL+K+MKG GT+E LIE+L TRT++++ I +AY ++
Sbjct: 78 GHFEHLMVALVTPPAVFDAKQLKKSMKGAGTNEDALIEILTTRTSRQMKDISQAYYTVYK 137
Query: 175 RSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAF 234
+SL D+ +TSG+ +K L++L R+E VD+ LA QDA+ LY AGE RWGTDE F
Sbjct: 138 KSLGDDISSETSGDFRKALLTLADGRRDESLKVDEHLAKQDAQILYKAGENRWGTDEDKF 197
Query: 235 NEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAER 294
E+L RS+ QL+ TF Y+ + KDI ++I+ E SG + L +V C ++ + AER
Sbjct: 198 TEILCLRSFPQLKLTFDEYRNISQKDIVDSIKGELSGHFEDLLLAIVNCVRNTPAFLAER 257
Query: 295 LYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVA 354
L++++KG GTDE TL RI+V+R+E+DL I+ +F++ Y SL ++SDTSGD+ L+
Sbjct: 258 LHRALKGIGTDEFTLNRIMVSRSEIDLLDIRTEFKKHYGYSLYSAIKSDTSGDYEITLLK 317
Query: 355 L 355
+
Sbjct: 318 I 318
Score = 53.5 bits (127), Expect = 3e-07
Identities = 27/65 (41%), Positives = 40/65 (61%)
Query: 292 AERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKL 351
AE + K+++G GTDE+ LI I+ R+ Q I ++Q Y K L D ++ D SG F L
Sbjct: 24 AEAIQKAIRGIGTDEKMLISILTERSNAQRQLIVKEYQAAYGKELKDDLKGDLSGHFEHL 83
Query: 352 LVALL 356
+VAL+
Sbjct: 84 MVALV 88
>gi|50845388 annexin A2 isoform 1 [Homo sapiens]
Length = 357
Score = 259 bits (663), Expect = 2e-69
Identities = 143/339 (42%), Positives = 209/339 (61%), Gaps = 3/339 (0%)
Query: 20 KGDSQPSTVVQPLSHPSRNGEPEAPQPAKAS--SPQGFDVDRDAKKLNKACKGMGTNEAA 77
K + STV + L S G+ P A S + FD +RDA + A K G +E
Sbjct: 14 KASFKMSTVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKTKGVDEVT 73
Query: 78 IIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELSGNFEKTALALLDRPSEYAARQLQ 137
I+ IL+ R++ +RQ I Y+ KEL LKS LSG+ E L LL P++Y A +L+
Sbjct: 74 IVNILTNRSNAQRQDIAFAYQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELK 133
Query: 138 KAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLL 197
+MKGLGTDE LIE++C+RTN+E+ I Y+ ++ LE D+ DTSG+ +K++V+L
Sbjct: 134 ASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALA 193
Query: 198 QANRNE-GDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQAYQIL 256
+ R E G +D +L QDA+DLYDAG R GTD + ++ +RS L+ F Y+
Sbjct: 194 KGRRAEDGSVIDYELIDQDARDLYDAGVKRKGTDVPKWISIMTERSVPHLQKVFDRYKSY 253
Query: 257 IGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAERLYKSMKGAGTDEETLIRIVVTR 316
D+ E+I +E GDL+ A+L LV+C Q+ YFA+RLY SMKG GT ++ LIRI+V+R
Sbjct: 254 SPYDMLESIRKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSR 313
Query: 317 AEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVAL 355
+EVD+ I+++F+ KY KSL ++ DT GD++K L+ L
Sbjct: 314 SEVDMLKIRSEFKRKYGKSLYYYIQQDTKGDYQKALLYL 352
>gi|4757756 annexin A2 isoform 2 [Homo sapiens]
Length = 339
Score = 259 bits (661), Expect = 3e-69
Identities = 142/333 (42%), Positives = 207/333 (62%), Gaps = 3/333 (0%)
Query: 26 STVVQPLSHPSRNGEPEAPQPAKAS--SPQGFDVDRDAKKLNKACKGMGTNEAAIIEILS 83
STV + L S G+ P A S + FD +RDA + A K G +E I+ IL+
Sbjct: 2 STVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILT 61
Query: 84 GRTSDERQQIKQKYKATYGKELEEVLKSELSGNFEKTALALLDRPSEYAARQLQKAMKGL 143
R++ +RQ I Y+ KEL LKS LSG+ E L LL P++Y A +L+ +MKGL
Sbjct: 62 NRSNAQRQDIAFAYQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELKASMKGL 121
Query: 144 GTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNE 203
GTDE LIE++C+RTN+E+ I Y+ ++ LE D+ DTSG+ +K++V+L + R E
Sbjct: 122 GTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAE 181
Query: 204 -GDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIE 262
G +D +L QDA+DLYDAG R GTD + ++ +RS L+ F Y+ D+
Sbjct: 182 DGSVIDYELIDQDARDLYDAGVKRKGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDML 241
Query: 263 EAIEEETSGDLQKAYLTLVRCAQDCEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQ 322
E+I +E GDL+ A+L LV+C Q+ YFA+RLY SMKG GT ++ LIRI+V+R+EVD+
Sbjct: 242 ESIRKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDML 301
Query: 323 GIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVAL 355
I+++F+ KY KSL ++ DT GD++K L+ L
Sbjct: 302 KIRSEFKRKYGKSLYYYIQQDTKGDYQKALLYL 334
>gi|50845386 annexin A2 isoform 2 [Homo sapiens]
Length = 339
Score = 259 bits (661), Expect = 3e-69
Identities = 142/333 (42%), Positives = 207/333 (62%), Gaps = 3/333 (0%)
Query: 26 STVVQPLSHPSRNGEPEAPQPAKAS--SPQGFDVDRDAKKLNKACKGMGTNEAAIIEILS 83
STV + L S G+ P A S + FD +RDA + A K G +E I+ IL+
Sbjct: 2 STVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILT 61
Query: 84 GRTSDERQQIKQKYKATYGKELEEVLKSELSGNFEKTALALLDRPSEYAARQLQKAMKGL 143
R++ +RQ I Y+ KEL LKS LSG+ E L LL P++Y A +L+ +MKGL
Sbjct: 62 NRSNAQRQDIAFAYQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELKASMKGL 121
Query: 144 GTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNE 203
GTDE LIE++C+RTN+E+ I Y+ ++ LE D+ DTSG+ +K++V+L + R E
Sbjct: 122 GTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAE 181
Query: 204 -GDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIE 262
G +D +L QDA+DLYDAG R GTD + ++ +RS L+ F Y+ D+
Sbjct: 182 DGSVIDYELIDQDARDLYDAGVKRKGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDML 241
Query: 263 EAIEEETSGDLQKAYLTLVRCAQDCEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQ 322
E+I +E GDL+ A+L LV+C Q+ YFA+RLY SMKG GT ++ LIRI+V+R+EVD+
Sbjct: 242 ESIRKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDML 301
Query: 323 GIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVAL 355
I+++F+ KY KSL ++ DT GD++K L+ L
Sbjct: 302 KIRSEFKRKYGKSLYYYIQQDTKGDYQKALLYL 334
>gi|209862831 annexin A2 isoform 2 [Homo sapiens]
Length = 339
Score = 259 bits (661), Expect = 3e-69
Identities = 142/333 (42%), Positives = 207/333 (62%), Gaps = 3/333 (0%)
Query: 26 STVVQPLSHPSRNGEPEAPQPAKAS--SPQGFDVDRDAKKLNKACKGMGTNEAAIIEILS 83
STV + L S G+ P A S + FD +RDA + A K G +E I+ IL+
Sbjct: 2 STVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILT 61
Query: 84 GRTSDERQQIKQKYKATYGKELEEVLKSELSGNFEKTALALLDRPSEYAARQLQKAMKGL 143
R++ +RQ I Y+ KEL LKS LSG+ E L LL P++Y A +L+ +MKGL
Sbjct: 62 NRSNAQRQDIAFAYQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELKASMKGL 121
Query: 144 GTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNE 203
GTDE LIE++C+RTN+E+ I Y+ ++ LE D+ DTSG+ +K++V+L + R E
Sbjct: 122 GTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAE 181
Query: 204 -GDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIE 262
G +D +L QDA+DLYDAG R GTD + ++ +RS L+ F Y+ D+
Sbjct: 182 DGSVIDYELIDQDARDLYDAGVKRKGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDML 241
Query: 263 EAIEEETSGDLQKAYLTLVRCAQDCEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQ 322
E+I +E GDL+ A+L LV+C Q+ YFA+RLY SMKG GT ++ LIRI+V+R+EVD+
Sbjct: 242 ESIRKEVKGDLENAFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDML 301
Query: 323 GIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVAL 355
I+++F+ KY KSL ++ DT GD++K L+ L
Sbjct: 302 KIRSEFKRKYGKSLYYYIQQDTKGDYQKALLYL 334
>gi|4502101 annexin I [Homo sapiens]
Length = 346
Score = 258 bits (659), Expect = 6e-69
Identities = 139/311 (44%), Positives = 195/311 (62%), Gaps = 1/311 (0%)
Query: 46 PAKASSPQG-FDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKE 104
P A SP F+ D L+KA G +EA II+IL+ R + +RQQIK Y GK
Sbjct: 32 PGSAVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKP 91
Query: 105 LEEVLKSELSGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIA 164
L+E LK L+G+ E+ LALL P+++ A +L+ AMKGLGTDE LIE+L +RTNKEI
Sbjct: 92 LDETLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIRD 151
Query: 165 IKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGE 224
I Y+ R L D+ DTSG+ + L+SL + +R+E V++DLA DA+ LY+AGE
Sbjct: 152 INRVYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDARALYEAGE 211
Query: 225 GRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCA 284
R GTD FN +L RSY QLR FQ Y D+ + ++ E GD++K +V+CA
Sbjct: 212 RRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCLTAIVKCA 271
Query: 285 QDCEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDT 344
+FAE+L+++MKG GT + LIRI+V+R+E+D+ IKA +Q+ Y SL + +T
Sbjct: 272 TSKPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLCQAILDET 331
Query: 345 SGDFRKLLVAL 355
GD+ K+LVAL
Sbjct: 332 KGDYEKILVAL 342
Score = 86.7 bits (213), Expect = 3e-17
Identities = 72/263 (27%), Positives = 128/263 (48%), Gaps = 22/263 (8%)
Query: 103 KELEEVLKSELSGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEI 162
+E + +KS G + PS A L KA+ G DE+ +I++L R N +
Sbjct: 19 QEYVQTVKSSKGGPGSAVSPYPTFNPSSDVAA-LHKAIMVKGVDEATIIDILTKRNNAQR 77
Query: 163 IAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDA 222
IK AY + + L+ +K +G+L++++++LL K A DA +L A
Sbjct: 78 QQIKAAYLQETGKPLDETLKKALTGHLEEVVLALL-----------KTPAQFDADELRAA 126
Query: 223 GEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVR 282
+G GTDE E+LA R+ K++R + Y+ + +D+ + I +TSGD + A L+L +
Sbjct: 127 MKGL-GTDEDTLIEILASRTNKEIRDINRVYREELKRDLAKDITSDTSGDFRNALLSLAK 185
Query: 283 --------CAQDCEDYFAERLYKS-MKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQ 333
+D D A LY++ + GTD I+ TR+ L+ + K+ + +
Sbjct: 186 GDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSK 245
Query: 334 KSLSDMVRSDTSGDFRKLLVALL 356
++ ++ + GD K L A++
Sbjct: 246 HDMNKVLDLELKGDIEKCLTAIV 268
Score = 70.9 bits (172), Expect = 2e-12
Identities = 51/164 (31%), Positives = 88/164 (53%), Gaps = 11/164 (6%)
Query: 47 AKASSPQGFDV-----DRDAKKLNKAC-KGMGTNEAAIIEILSGRTSDERQQIKQKYKAT 100
AK + F V D DA+ L +A + GT+ IL+ R+ + +++ QKY
Sbjct: 184 AKGDRSEDFGVNEDLADSDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKY 243
Query: 101 YGKELEEVLKSELSGNFEKTALALL----DRPSEYAARQLQKAMKGLGTDESVLIEVLCT 156
++ +VL EL G+ EK A++ +P+ + A +L +AMKG+GT LI ++ +
Sbjct: 244 SKHDMNKVLDLELKGDIEKCLTAIVKCATSKPA-FFAEKLHQAMKGVGTRHKALIRIMVS 302
Query: 157 RTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQAN 200
R+ ++ IK YQ+++ SL + +T G+ +KILV+L N
Sbjct: 303 RSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN 346
>gi|48762937 annexin A10 [Homo sapiens]
Length = 324
Score = 202 bits (515), Expect = 3e-52
Identities = 109/301 (36%), Positives = 183/301 (60%), Gaps = 1/301 (0%)
Query: 55 FDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELS 114
F+ DA+ L A +G ++ +I IL+ R + +R I + Y++ YG++L ++ +LS
Sbjct: 17 FNPIMDAQMLGGALQGFDCDKDMLINILTQRCNAQRMMIAEAYQSMYGRDLIGDMREQLS 76
Query: 115 GNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFD 174
+F+ L+ P Y A +L AMKG+GTDE+ LIE+L +RTN EI ++EAY +
Sbjct: 77 DHFKDVMAGLMYPPPLYDAHELWHAMKGVGTDENCLIEILASRTNGEIFQMREAYCLQYS 136
Query: 175 RSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAF 234
+L+ D+ +TSG+ + L++L+Q R EG D +A QDA L++A + + G +
Sbjct: 137 NNLQEDIYSETSGHFRDTLMNLVQGTREEG-YTDPAMAAQDAMVLWEACQQKTGEHKTML 195
Query: 235 NEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAER 294
+L +SY+QLR FQ +Q + G+D+ +AI E G Q+ + +V C +D YFA R
Sbjct: 196 QMILCNKSYQQLRLVFQEFQNISGQDMVDAINECYDGYFQELLVAIVLCVRDKPAYFAYR 255
Query: 295 LYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVA 354
LY ++ G +T+IRI++ R+E+DL I+ +++E+Y KSL +R+ SG ++K L+A
Sbjct: 256 LYSAIHDFGFHNKTVIRILIARSEIDLLTIRKRYKERYGKSLFHDIRNFASGHYKKALLA 315
Query: 355 L 355
+
Sbjct: 316 I 316
Score = 73.9 bits (180), Expect = 2e-13
Identities = 59/233 (25%), Positives = 116/233 (49%), Gaps = 22/233 (9%)
Query: 133 ARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKI 192
A+ L A++G D+ +LI +L R N + + I EAYQ ++ R L D++ S + K +
Sbjct: 23 AQMLGGALQGFDCDKDMLINILTQRCNAQRMMIAEAYQSMYGRDLIGDMREQLSDHFKDV 82
Query: 193 LVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQA 252
+ L+ DA +L+ A +G GTDE E+LA R+ ++ +A
Sbjct: 83 MAGLMYPPPL-----------YDAHELWHAMKGV-GTDENCLIEILASRTNGEIFQMREA 130
Query: 253 YQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYF--------AERLYKSMKGAGT 304
Y + +++E I ETSG + + LV+ ++ E Y A L+++ +
Sbjct: 131 YCLQYSNNLQEDIYSETSGHFRDTLMNLVQGTRE-EGYTDPAMAAQDAMVLWEACQQKTG 189
Query: 305 DEETLIRIVV-TRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVALL 356
+ +T++++++ ++ L+ + +FQ + + D + G F++LLVA++
Sbjct: 190 EHKTMLQMILCNKSYQQLRLVFQEFQNISGQDMVDAINECYDGYFQELLVAIV 242
Score = 56.6 bits (135), Expect = 3e-08
Identities = 41/142 (28%), Positives = 71/142 (50%), Gaps = 4/142 (2%)
Query: 215 DAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQ 274
DA+ L A +G + D+ +L +R Q +AYQ + G+D+ + E+ S +
Sbjct: 22 DAQMLGGALQG-FDCDKDMLINILTQRCNAQRMMIAEAYQSMYGRDLIGDMREQLSDHFK 80
Query: 275 KAYLTLVRCAQDCEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQK 334
L+ Y A L+ +MKG GTDE LI I+ +R ++ ++ + +Y
Sbjct: 81 DVMAGLM---YPPPLYDAHELWHAMKGVGTDENCLIEILASRTNGEIFQMREAYCLQYSN 137
Query: 335 SLSDMVRSDTSGDFRKLLVALL 356
+L + + S+TSG FR L+ L+
Sbjct: 138 NLQEDIYSETSGHFRDTLMNLV 159
>gi|145864465 annexin A9 [Homo sapiens]
Length = 345
Score = 165 bits (417), Expect = 7e-41
Identities = 97/302 (32%), Positives = 176/302 (58%), Gaps = 4/302 (1%)
Query: 55 FDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELS 114
F VD+DA++L +A G G + +AI+++L+ R+ ++RQ I + ++ ++L + L++ LS
Sbjct: 41 FSVDKDAQRLLRAITGQGVDRSAIVDVLTNRSREQRQLISRNFQERTQQDLMKSLQAALS 100
Query: 115 GNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFD 174
GN E+ +ALL +++ A++L+ A+K + V IE+L TRT ++ Y+ F
Sbjct: 101 GNLERIVMALLQPTAQFDAQELRTALKASDSAVDVAIEILATRTPPQLQECLAVYKHNFQ 160
Query: 175 RSLESDVKGDTSGNLKKILVSLLQANRNE-GDDVDKDLAGQDAKDLYDAGEGRWGTDELA 233
D+ +TSG L+ +L++L + R+ +D +LA QD + L A EG + E
Sbjct: 161 VEAVDDITSETSGILQDLLLALAKGGRDSYSGIIDYNLAEQDVQALQRA-EG--PSREET 217
Query: 234 FNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAE 293
+ V +R+ + L F YQ G+++EEA++ GD Q A L L ++ YFA+
Sbjct: 218 WVPVFTQRNPEHLIRVFDQYQRSTGQELEEAVQNRFHGDAQVALLGLASVIKNTPLYFAD 277
Query: 294 RLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLV 353
+L+++++ + + LIRI+++R E DL I+A+F++K+ KSL ++ GD + L+
Sbjct: 278 KLHQALQETEPNYQVLIRILISRCETDLLSIRAEFRKKFGKSLYSSLQDAVKGDCQSALL 337
Query: 354 AL 355
AL
Sbjct: 338 AL 339
Score = 43.1 bits (100), Expect = 4e-04
Identities = 20/68 (29%), Positives = 39/68 (57%)
Query: 289 DYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDF 348
D A+RL +++ G G D ++ ++ R+ Q I FQE+ Q+ L +++ SG+
Sbjct: 44 DKDAQRLLRAITGQGVDRSAIVDVLTNRSREQRQLISRNFQERTQQDLMKSLQAALSGNL 103
Query: 349 RKLLVALL 356
++++ALL
Sbjct: 104 ERIVMALL 111
>gi|239752501 PREDICTED: hypothetical protein XP_002347094 [Homo
sapiens]
Length = 112
Score = 103 bits (258), Expect = 2e-22
Identities = 51/109 (46%), Positives = 74/109 (67%)
Query: 232 LAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVRCAQDCEDYF 291
+ F +L RS L F+ Y+ + K IE++I+ ET G L++A LT+V+C Q+ YF
Sbjct: 1 MKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHSYF 60
Query: 292 AERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMV 340
AERLY +MKGAGT + TLIR +V+R+E+DL IK F++ Y K+LS M+
Sbjct: 61 AERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMI 109
Score = 50.4 bits (119), Expect = 2e-06
Identities = 29/104 (27%), Positives = 57/104 (54%), Gaps = 3/104 (2%)
Query: 79 IEILSGRTSDERQQIKQKYKATYGKELEEVLKSELSGNFEKTALALL---DRPSEYAARQ 135
I IL R++ ++ ++Y+ K +E+ +KSE G+ E+ L ++ Y A +
Sbjct: 4 ITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHSYFAER 63
Query: 136 LQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLES 179
L AMKG GT + LI + +R+ ++ IK +++++ ++L S
Sbjct: 64 LYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSS 107
Score = 43.9 bits (102), Expect = 2e-04
Identities = 28/115 (24%), Positives = 59/115 (51%), Gaps = 9/115 (7%)
Query: 151 IEVLCTRTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKD 210
I +LCTR+ ++ + E Y+++ ++S+E +K +T G+L++ ++++++ +N
Sbjct: 4 ITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQN-------- 55
Query: 211 LAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAI 265
L A+ LY A +G GT + + RS L ++ + GK + I
Sbjct: 56 LHSYFAERLYYAMKGA-GTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMI 109
Score = 32.3 bits (72), Expect = 0.67
Identities = 16/49 (32%), Positives = 26/49 (53%)
Query: 61 AKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVL 109
A++L A KG GT + +I + R+ + IK +K YGK L ++
Sbjct: 61 AERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMI 109
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 37.4 bits (85), Expect = 0.021
Identities = 44/224 (19%), Positives = 90/224 (40%), Gaps = 28/224 (12%)
Query: 16 QQLPKGDSQPSTVVQPLSHPSRNGEPEAPQPAKASSPQGFD-VDRDAKKLNKACKGMGTN 74
Q LPK D + + ++ P +P+ +P K + + D D + + K+ +G+
Sbjct: 1304 QSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDT 1363
Query: 75 -------EAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELSGNFEKTALALLD- 126
+++ EI S +DE+ +K K ++ +E S+L+ E T L++L+
Sbjct: 1364 GYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLA-KLESTVLSILEA 1422
Query: 127 --------------RPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRL 172
+P E + Q + K E++ I T + +EI +E +
Sbjct: 1423 QASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEI----TISEEEIKESQEERKDT 1478
Query: 173 FDRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDA 216
F + + D+ K V + R D V++ +++
Sbjct: 1479 FKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENS 1522
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 37.4 bits (85), Expect = 0.021
Identities = 44/224 (19%), Positives = 90/224 (40%), Gaps = 28/224 (12%)
Query: 16 QQLPKGDSQPSTVVQPLSHPSRNGEPEAPQPAKASSPQGFD-VDRDAKKLNKACKGMGTN 74
Q LPK D + + ++ P +P+ +P K + + D D + + K+ +G+
Sbjct: 1304 QSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDT 1363
Query: 75 -------EAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELSGNFEKTALALLD- 126
+++ EI S +DE+ +K K ++ +E S+L+ E T L++L+
Sbjct: 1364 GYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLA-KLESTVLSILEA 1422
Query: 127 --------------RPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRL 172
+P E + Q + K E++ I T + +EI +E +
Sbjct: 1423 QASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEI----TISEEEIKESQEERKDT 1478
Query: 173 FDRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDA 216
F + + D+ K V + R D V++ +++
Sbjct: 1479 FKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENS 1522
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 33.5 bits (75), Expect = 0.30
Identities = 58/261 (22%), Positives = 108/261 (41%), Gaps = 18/261 (6%)
Query: 65 NKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELSGNFEKTALAL 124
NK + + T +A L ++ + QQ++++ KA + E+ LK + N EK+ LA
Sbjct: 1074 NKLIQELKTAKAT----LEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVN-EKSKLAE 1128
Query: 125 LDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLESDVKGD 184
++ E RQ ++ K +S +E + KEI +K+A Q L + LE K D
Sbjct: 1129 IE---EIKCRQEKEITKLNEELKSHKLESI-----KEITNLKDAKQLLIQQKLELQGKAD 1180
Query: 185 T----SGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAK 240
+ K+ L + E +++ K+ ++AK + E G + NE
Sbjct: 1181 SLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLT 1240
Query: 241 RSYKQLRATFQAYQILIGKDIEEAIE-EETSGDLQKAYLTLVRCAQDCEDYFAERLYKSM 299
L + E E+ + DL+ L Q+ +D L + +
Sbjct: 1241 MQITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCL 1300
Query: 300 KGAGTDEETLIRIVVTRAEVD 320
KG G E+ +++ + ++D
Sbjct: 1301 KGEGEIEKLQTKVLELQRKLD 1321
>gi|62821787 COBL-like 1 [Homo sapiens]
Length = 1166
Score = 33.1 bits (74), Expect = 0.39
Identities = 31/96 (32%), Positives = 45/96 (46%), Gaps = 16/96 (16%)
Query: 27 TVVQPLSHPSRNGEPEAPQPAKASSPQGFDVDRDAKKLNKACKGM---------GTNEAA 77
T +QP+ + EA P + SSP+ F +++ A K M GT EAA
Sbjct: 383 TALQPVDGVPPDSASEANSPEELSSPETFHPGLSSQEQCTAPKLMEETSVFECPGTPEAA 442
Query: 78 IIEILSGRTSD-ERQQIKQKYKATYGKELEEVLKSE 112
I + SG +SD ++I +K +EL EV K E
Sbjct: 443 ITSLTSGISSDYSLEEIDEK------EELSEVPKVE 472
>gi|148806902 TBC1 domain family, member 12 [Homo sapiens]
Length = 775
Score = 32.7 bits (73), Expect = 0.51
Identities = 26/84 (30%), Positives = 43/84 (51%), Gaps = 12/84 (14%)
Query: 93 IKQKYKATYGKELEEVLKSELSGNFE-----KTALALLDRPSEYAARQLQKAMKGLGTDE 147
I+Q+Y+A G+ + +S NFE TAL L DRPS A+ +++A++
Sbjct: 363 IQQEYEARTGRTCKPPPQSSRRKNFEFEPLSTTALILEDRPSNLPAKSVEEALR----HR 418
Query: 148 SVLIEVLCTRTNKEIIAIKEAYQR 171
E++ +E IKEA++R
Sbjct: 419 QEYDEMVAEAKKRE---IKEAHKR 439
>gi|22035569 GC-rich sequence DNA-binding factor candidate isoform 2
[Homo sapiens]
Length = 815
Score = 32.3 bits (72), Expect = 0.67
Identities = 30/140 (21%), Positives = 59/140 (42%), Gaps = 15/140 (10%)
Query: 14 GSQQLPKGDSQPSTVVQPLSHPSRNGEPEAPQPAKASSPQGFDVDRDAKKLNKACKGMGT 73
G L G S PS + L + G P +P P+ R+ K++ +A
Sbjct: 53 GESLLGPGPSPPSALTPGLGAEAGGGFPGGAEPGNGLKPR--KRPRENKEVPRASLLSFQ 110
Query: 74 NEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELSGNFEKTALALLDRPSEYAA 133
+E +E +++ + K++Y K++ ++LK E + EK+ + S +
Sbjct: 111 DE-----------EEENEEVFKVKKSSYSKKIVKLLKKEYKEDLEKSKIKTELNSSAESE 159
Query: 134 RQLQKA--MKGLGTDESVLI 151
+ L K +K ++ V+I
Sbjct: 160 QPLDKTGHVKDTNQEDGVII 179
>gi|22035565 GC-rich sequence DNA-binding factor candidate isoform 1
[Homo sapiens]
Length = 917
Score = 32.3 bits (72), Expect = 0.67
Identities = 30/140 (21%), Positives = 59/140 (42%), Gaps = 15/140 (10%)
Query: 14 GSQQLPKGDSQPSTVVQPLSHPSRNGEPEAPQPAKASSPQGFDVDRDAKKLNKACKGMGT 73
G L G S PS + L + G P +P P+ R+ K++ +A
Sbjct: 53 GESLLGPGPSPPSALTPGLGAEAGGGFPGGAEPGNGLKPR--KRPRENKEVPRASLLSFQ 110
Query: 74 NEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELSGNFEKTALALLDRPSEYAA 133
+E +E +++ + K++Y K++ ++LK E + EK+ + S +
Sbjct: 111 DE-----------EEENEEVFKVKKSSYSKKIVKLLKKEYKEDLEKSKIKTELNSSAESE 159
Query: 134 RQLQKA--MKGLGTDESVLI 151
+ L K +K ++ V+I
Sbjct: 160 QPLDKTGHVKDTNQEDGVII 179
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.130 0.352
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,660,643
Number of Sequences: 37866
Number of extensions: 592868
Number of successful extensions: 2548
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 47
Number of HSP's successfully gapped in prelim test: 44
Number of HSP's that attempted gapping in prelim test: 2195
Number of HSP's gapped (non-prelim): 162
length of query: 357
length of database: 18,247,518
effective HSP length: 103
effective length of query: 254
effective length of database: 14,347,320
effective search space: 3644219280
effective search space used: 3644219280
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.