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Search of human proteins with 51093845
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|51093845 dual specificity phosphatase 18 [Homo sapiens]
(188 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|51093845 dual specificity phosphatase 18 [Homo sapiens] 382 e-106
gi|225703077 dual specificity phosphatase 21 [Homo sapiens] 273 6e-74
gi|5902002 dual specificity phosphatase 14 [Homo sapiens] 201 3e-52
gi|4758204 dual specificity phosphatase 1 [Homo sapiens] 100 7e-22
gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens] 95 3e-20
gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens] 95 3e-20
gi|29826315 dual specificity phosphatase 15 isoform a [Homo sapi... 92 3e-19
gi|75750526 dual specificity phosphatase 28 [Homo sapiens] 90 1e-18
gi|62865890 dual specificity phosphatase 5 [Homo sapiens] 89 2e-18
gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo sapi... 88 4e-18
gi|153281158 dual specificity phosphatase 8 [Homo sapiens] 87 6e-18
gi|9910432 dual specificity phosphatase 22 [Homo sapiens] 82 2e-16
gi|38372911 dual specificity phosphatase 16 [Homo sapiens] 81 5e-16
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens] 81 6e-16
gi|4758206 dual specificity phosphatase 2 [Homo sapiens] 80 1e-15
gi|239582767 slingshot homolog 3 [Homo sapiens] 78 4e-15
gi|13128968 dual specificity phosphatase 26 [Homo sapiens] 78 4e-15
gi|21536333 dual specificity phosphatase 10 isoform b [Homo sapi... 77 7e-15
gi|21536331 dual specificity phosphatase 10 isoform b [Homo sapi... 77 7e-15
gi|56117818 muscle-restricted dual specificity phosphatase isofo... 74 6e-14
gi|238231453 dual specificity phosphatase 7 [Homo sapiens] 74 1e-13
gi|56237018 testis and skeletal muscle-specific dual specificity... 73 2e-13
gi|56117822 testis and skeletal muscle-specific dual specificity... 73 2e-13
gi|56117820 testis and skeletal muscle-specific dual specificity... 73 2e-13
gi|4503421 dual specificity phosphatase 9 [Homo sapiens] 72 3e-13
gi|239047414 slingshot 1 isoform 1 [Homo sapiens] 71 6e-13
gi|239047498 slingshot 1 isoform 3 [Homo sapiens] 71 6e-13
gi|239047441 slingshot 1 isoform 2 [Homo sapiens] 71 6e-13
gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo ... 70 8e-13
gi|194733759 serine/threonine/tyrosine interacting protein [Homo... 70 8e-13
>gi|51093845 dual specificity phosphatase 18 [Homo sapiens]
Length = 188
Score = 382 bits (981), Expect = e-106
Identities = 188/188 (100%), Positives = 188/188 (100%)
Query: 1 MTAPSCAFPVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTL 60
MTAPSCAFPVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTL
Sbjct: 1 MTAPSCAFPVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTL 60
Query: 61 YEDIQYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLM 120
YEDIQYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLM
Sbjct: 61 YEDIQYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLM 120
Query: 121 KYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVGMIPDIYEK 180
KYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVGMIPDIYEK
Sbjct: 121 KYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVGMIPDIYEK 180
Query: 181 EVRLMIPL 188
EVRLMIPL
Sbjct: 181 EVRLMIPL 188
>gi|225703077 dual specificity phosphatase 21 [Homo sapiens]
Length = 190
Score = 273 bits (698), Expect = 6e-74
Identities = 131/190 (68%), Positives = 163/190 (85%), Gaps = 2/190 (1%)
Query: 1 MTAPSCAFPVQ--FRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVN 58
MTA + +F +QPS+ SQIT+SL++SNGVAAN+KL+LSSN+IT ++N SVEVVN
Sbjct: 1 MTASASSFSSSQGVQQPSIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVN 60
Query: 59 TLYEDIQYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAY 118
+E IQY++VPV D+ +SRL DFFDPIAD IH+++M+QGRTLLHC AGVSRSA+LCLAY
Sbjct: 61 VFFEGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAY 120
Query: 119 LMKYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVGMIPDIY 178
LMKYH+MSLLDAHTWTKS RPIIRPN+GFWEQLI+YEF+LF NTV M++SPVG IPDIY
Sbjct: 121 LMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFNNNTVRMINSPVGNIPDIY 180
Query: 179 EKEVRLMIPL 188
EK++R+MI +
Sbjct: 181 EKDLRMMISM 190
>gi|5902002 dual specificity phosphatase 14 [Homo sapiens]
Length = 198
Score = 201 bits (511), Expect = 3e-52
Identities = 90/179 (50%), Positives = 130/179 (72%)
Query: 9 PVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTLYEDIQYMQ 68
P + + G++QIT SL++ G A+N+ +L + IT ++N ++E+ N + +Y++
Sbjct: 16 PRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFEYVK 75
Query: 69 VPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLL 128
VP+AD P++ + +FD +AD IHSV K G TL+HCAAGVSRSA LC+AYLMK+H + LL
Sbjct: 76 VPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLL 135
Query: 129 DAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVGMIPDIYEKEVRLMIP 187
+A+ W K+ RP+IRPN GFW QLI YE QLFGK+TV MV +P G++PD+YEKE R ++P
Sbjct: 136 EAYNWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVKMVQTPYGIVPDVYEKESRHLMP 194
>gi|4758204 dual specificity phosphatase 1 [Homo sapiens]
Length = 367
Score = 100 bits (249), Expect = 7e-22
Identities = 59/172 (34%), Positives = 89/172 (51%), Gaps = 4/172 (2%)
Query: 5 SCAFPVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTLYEDI 64
SC+ P+ + G +I LY+ + A+ K ML + IT +INVS N
Sbjct: 163 SCSTPLYDQ----GGPVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHY 218
Query: 65 QYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHA 124
QY +PV D+ + + +F+ D I S++ GR +HC AG+SRSA +CLAYLM+ +
Sbjct: 219 QYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNR 278
Query: 125 MSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVGMIPD 176
+ L +A + K R II PN F QL+ +E Q+ + SP + D
Sbjct: 279 VKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAPHCSAEAGSPAMAVLD 330
>gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]
Length = 394
Score = 95.1 bits (235), Expect = 3e-20
Identities = 57/168 (33%), Positives = 88/168 (52%), Gaps = 4/168 (2%)
Query: 5 SCAFPVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTLYEDI 64
SC P+ + G +I LY+ + A + ML + IT ++NVS + N
Sbjct: 185 SCGTPLHDQ----GGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHY 240
Query: 65 QYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHA 124
QY +PV D+ + + +F ++I +V+ +GR L+HC AG+SRSA +CLAYLM
Sbjct: 241 QYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKR 300
Query: 125 MSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVG 172
+ L +A + K R II PN F QL+ +E Q+ + +SP G
Sbjct: 301 VRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLATSCAAEAASPSG 348
>gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]
Length = 303
Score = 95.1 bits (235), Expect = 3e-20
Identities = 57/168 (33%), Positives = 88/168 (52%), Gaps = 4/168 (2%)
Query: 5 SCAFPVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTLYEDI 64
SC P+ + G +I LY+ + A + ML + IT ++NVS + N
Sbjct: 94 SCGTPLHDQ----GGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHY 149
Query: 65 QYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHA 124
QY +PV D+ + + +F ++I +V+ +GR L+HC AG+SRSA +CLAYLM
Sbjct: 150 QYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKR 209
Query: 125 MSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVG 172
+ L +A + K R II PN F QL+ +E Q+ + +SP G
Sbjct: 210 VRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLATSCAAEAASPSG 257
>gi|29826315 dual specificity phosphatase 15 isoform a [Homo
sapiens]
Length = 235
Score = 91.7 bits (226), Expect = 3e-19
Identities = 53/171 (30%), Positives = 88/171 (51%), Gaps = 2/171 (1%)
Query: 18 SGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTLYEDIQYMQVPVADSPNS 77
+G++++ LY+ N + A + L N+IT +I++ E L +DI Y+++PVAD+P
Sbjct: 3 NGMTKVLPGLYLGNFIDAKDLDQLGRNKITHIISIH-ESPQPLLQDITYLRIPVADTPEV 61
Query: 78 RLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSC 137
+ F + IH + G L+HC AG+SRS + AY+M + D K+
Sbjct: 62 PIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKAT 121
Query: 138 RPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVGMIPDIYEKEVRLMIPL 188
RPI PN GF +QL + + + + G P E+E+R ++PL
Sbjct: 122 RPIANPNPGFRQQLEEFGW-ASSQKLRRQLEERFGESPFRDEEELRALLPL 171
>gi|75750526 dual specificity phosphatase 28 [Homo sapiens]
Length = 176
Score = 90.1 bits (222), Expect = 1e-18
Identities = 50/157 (31%), Positives = 80/157 (50%)
Query: 20 LSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTLYEDIQYMQVPVADSPNSRL 79
L ++ SL++ + AA + L+ +T+ +NVS + + ++VPV D P L
Sbjct: 19 LVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRAPGVAELRVPVFDDPAEDL 78
Query: 80 CDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSCRP 139
+P + + G L++C G SRSAA+C AYLM++ +SL A KS RP
Sbjct: 79 LAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVKSARP 138
Query: 140 IIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVGMIPD 176
+ PN GFW QL YE L ++ + +G+ P+
Sbjct: 139 VAEPNPGFWSQLQKYEEALQAQSCLQGEPPALGLGPE 175
>gi|62865890 dual specificity phosphatase 5 [Homo sapiens]
Length = 384
Score = 89.4 bits (220), Expect = 2e-18
Identities = 48/140 (34%), Positives = 72/140 (51%)
Query: 19 GLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTLYEDIQYMQVPVADSPNSR 78
G +I LY+ + A+ L++ IT ++NVS + Y +PV DS +
Sbjct: 178 GPVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVEDSHTAD 237
Query: 79 LCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSCR 138
+ F D I V K G+ L+HC AG+SRS +C+AYLMK L +A + K R
Sbjct: 238 ISSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRR 297
Query: 139 PIIRPNSGFWEQLIHYEFQL 158
++ PN GF QL+ YE ++
Sbjct: 298 SMVSPNFGFMGQLLQYESEI 317
>gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo
sapiens]
Length = 217
Score = 88.2 bits (217), Expect = 4e-18
Identities = 45/129 (34%), Positives = 69/129 (53%)
Query: 27 LYISNGVAANNKLMLSSNQITMVINVSVEVVNTLYEDIQYMQVPVADSPNSRLCDFFDPI 86
L + + AA++ L N++T ++NV+ V N D Y + + D P + + +F
Sbjct: 73 LLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDLPETNILSYFPEC 132
Query: 87 ADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSCRPIIRPNSG 146
+ I + K G L+HC AGVSR+AA+ + +LM S A + K+ RP I PNSG
Sbjct: 133 FEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSICPNSG 192
Query: 147 FWEQLIHYE 155
F EQL Y+
Sbjct: 193 FMEQLRTYQ 201
>gi|153281158 dual specificity phosphatase 8 [Homo sapiens]
Length = 625
Score = 87.4 bits (215), Expect = 6e-18
Identities = 51/160 (31%), Positives = 85/160 (53%), Gaps = 5/160 (3%)
Query: 4 PSCAFPVQFRQPSVS----GLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNT 59
P+ P+ QP + GL++I LY+ + NK +++ N I+ V+N S
Sbjct: 141 PAALLPMSLSQPCLPVPSVGLTRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKP 200
Query: 60 LYE-DIQYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAY 118
+ + ++M+VP+ D+ +L + D + I ++ + ++HC AG+SRSA + +AY
Sbjct: 201 DFICESRFMRVPINDNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAY 260
Query: 119 LMKYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQL 158
+MK MS DA+ + K RP I PN F QL+ YE L
Sbjct: 261 IMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYERSL 300
>gi|9910432 dual specificity phosphatase 22 [Homo sapiens]
Length = 184
Score = 82.4 bits (202), Expect = 2e-16
Identities = 50/148 (33%), Positives = 75/148 (50%), Gaps = 6/148 (4%)
Query: 18 SGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTLYEDIQYMQVPVADSPNS 77
+G+++I LYI N A + LS N++T +++V + + E ++Y+ +P ADSP+
Sbjct: 3 NGMNKILPGLYIGNFKDARDAEQLSKNKVTHILSVH-DSARPMLEGVKYLCIPAADSPSQ 61
Query: 78 RLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSC 137
L F IH ++ L+HC AGVSRS L +AY+M DA ++
Sbjct: 62 NLTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRAG 121
Query: 138 RPIIRPNSGFWEQLIHYEFQLFGKNTVH 165
R PN GF QL Q F K+ VH
Sbjct: 122 RSCANPNVGFQRQL-----QEFEKHEVH 144
>gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
Length = 665
Score = 81.3 bits (199), Expect = 5e-16
Identities = 48/138 (34%), Positives = 73/138 (52%), Gaps = 1/138 (0%)
Query: 19 GLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTLY-EDIQYMQVPVADSPNS 77
G ++I +LY+ NK ++ N I V+N S + + +++VPV DS
Sbjct: 158 GPTRILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCE 217
Query: 78 RLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSC 137
++ + D D I + G L+HC AG+SRSA + +AY+MK MSL +A+ + K
Sbjct: 218 KILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEK 277
Query: 138 RPIIRPNSGFWEQLIHYE 155
RP I PN F QL+ YE
Sbjct: 278 RPTISPNFNFLGQLLDYE 295
>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
Length = 482
Score = 80.9 bits (198), Expect = 6e-16
Identities = 49/141 (34%), Positives = 71/141 (50%), Gaps = 2/141 (1%)
Query: 20 LSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTLYED--IQYMQVPVADSPNS 77
L+ I L++ N A + + I VINV+ + YE Y ++P DS
Sbjct: 322 LTPILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQ 381
Query: 78 RLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSC 137
L +F+ + I L+HC AGVSRSA + +AYLMK+ M++ DA+ + K
Sbjct: 382 NLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGK 441
Query: 138 RPIIRPNSGFWEQLIHYEFQL 158
RPII PN F QL+ +E L
Sbjct: 442 RPIISPNLNFMGQLLEFEEDL 462
>gi|4758206 dual specificity phosphatase 2 [Homo sapiens]
Length = 314
Score = 79.7 bits (195), Expect = 1e-15
Identities = 47/140 (33%), Positives = 73/140 (52%)
Query: 19 GLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTLYEDIQYMQVPVADSPNSR 78
G +I L++ + +++ L + IT V+NVS N +Y +PV D+
Sbjct: 172 GPVEILPYLFLGSCSHSSDLQGLQACGITAVLNVSASCPNHFEGLFRYKSIPVEDNQMVE 231
Query: 79 LCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSCR 138
+ +F I V+ GR L+HC AG+SRSA +CLAYLM+ + L +A + K R
Sbjct: 232 ISAWFQEAIGFIDWVKNSGGRVLVHCQAGISRSATICLAYLMQSRRVRLDEAFDFVKQRR 291
Query: 139 PIIRPNSGFWEQLIHYEFQL 158
+I PN F QL+ +E Q+
Sbjct: 292 GVISPNFSFMGQLLQFETQV 311
>gi|239582767 slingshot homolog 3 [Homo sapiens]
Length = 659
Score = 78.2 bits (191), Expect = 4e-15
Identities = 51/152 (33%), Positives = 73/152 (48%)
Query: 21 SQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTLYEDIQYMQVPVADSPNSRLC 80
S+I LY+ + A N L N++T ++N++ E+ N E Y V + D +++L
Sbjct: 330 SRIFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLWDEESAQLL 389
Query: 81 DFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSCRPI 140
+ I + + L+HC GVSRSAA LAY MK + SL A + RPI
Sbjct: 390 PHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPI 449
Query: 141 IRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVG 172
RPN GF QL Y+ L H+ VG
Sbjct: 450 ARPNPGFLRQLQIYQGILTASRQSHVWEQKVG 481
>gi|13128968 dual specificity phosphatase 26 [Homo sapiens]
Length = 211
Score = 78.2 bits (191), Expect = 4e-15
Identities = 56/143 (39%), Positives = 76/143 (53%), Gaps = 7/143 (4%)
Query: 22 QITKSLYISNGVAANNKLMLSSNQITMVINVSVEV---VNTLYED--IQYMQVPVADSPN 76
++ LY+ + ANN+ L IT V+N S YE I+Y+ V DSP
Sbjct: 64 EVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPA 123
Query: 77 SRLCDFFDPIADHIH-SVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTK 135
+ F AD IH ++ G+ L+HCA GVSRSA L LAYLM YH ++L++A K
Sbjct: 124 FDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVK 183
Query: 136 SCRPIIRPNSGFWEQLIHYEFQL 158
R II PN GF QL+ + +L
Sbjct: 184 DHRGII-PNRGFLRQLLALDRRL 205
>gi|21536333 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 77.4 bits (189), Expect = 7e-15
Identities = 44/115 (38%), Positives = 61/115 (53%), Gaps = 2/115 (1%)
Query: 46 ITMVINVSVEVVNTLYED--IQYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLH 103
I VINV+ + YE Y ++P DS L +F+ + I L+H
Sbjct: 6 IGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIH 65
Query: 104 CAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQL 158
C AGVSRSA + +AYLMK+ M++ DA+ + K RPII PN F QL+ +E L
Sbjct: 66 CQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 120
>gi|21536331 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 77.4 bits (189), Expect = 7e-15
Identities = 44/115 (38%), Positives = 61/115 (53%), Gaps = 2/115 (1%)
Query: 46 ITMVINVSVEVVNTLYED--IQYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLH 103
I VINV+ + YE Y ++P DS L +F+ + I L+H
Sbjct: 6 IGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIH 65
Query: 104 CAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQL 158
C AGVSRSA + +AYLMK+ M++ DA+ + K RPII PN F QL+ +E L
Sbjct: 66 CQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 120
>gi|56117818 muscle-restricted dual specificity phosphatase isoform
1 [Homo sapiens]
Length = 188
Score = 74.3 bits (181), Expect = 6e-14
Identities = 51/152 (33%), Positives = 75/152 (49%), Gaps = 8/152 (5%)
Query: 16 SVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVV------NTLYEDIQYMQV 69
S S + ++ +L+I + ANN+ L IT V+N + + + + + Y+ V
Sbjct: 34 SCSRVDEVWPNLFIGDAATANNRFELWKLGITHVLNAAHKGLYCQGGPDFYGSSVSYLGV 93
Query: 70 PVADSPNSRLCDFFDPIADHIHSVEMKQG-RTLLHCAAGVSRSAALCLAYLMKYHAMSLL 128
P D P+ + +F AD IH G + L+HC GVSRSA L LAYLM + +SL
Sbjct: 94 PAHDLPDFDISAYFSSAADFIHRALNTPGAKVLVHCVVGVSRSATLVLAYLMLHQRLSLR 153
Query: 129 DAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFG 160
A + R + PN GF QL + QL G
Sbjct: 154 QAVITVRQHRWVF-PNRGFLHQLCRLDQQLRG 184
>gi|238231453 dual specificity phosphatase 7 [Homo sapiens]
Length = 419
Score = 73.6 bits (179), Expect = 1e-13
Identities = 47/149 (31%), Positives = 72/149 (48%), Gaps = 4/149 (2%)
Query: 9 PVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTLYE--DIQY 66
PV QP+ QI LY+ + N +L I ++NV+ + N + Y
Sbjct: 236 PVPSSQPAFP--VQILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTY 293
Query: 67 MQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMS 126
Q+P++D + L FF I K+ L+HC AG+SRS + +AYLM+ +S
Sbjct: 294 KQIPISDHWSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLS 353
Query: 127 LLDAHTWTKSCRPIIRPNSGFWEQLIHYE 155
L DA+ + K + I PN F QL+ +E
Sbjct: 354 LNDAYDFVKRKKSNISPNFNFMGQLLDFE 382
>gi|56237018 testis and skeletal muscle-specific dual specificity
phosphatase isoform 6 [Homo sapiens]
Length = 198
Score = 72.8 bits (177), Expect = 2e-13
Identities = 50/144 (34%), Positives = 80/144 (55%), Gaps = 9/144 (6%)
Query: 16 SVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVS-----VEVVNTLYE--DIQYMQ 68
+++ + ++ SL++ + AA +K L IT V+N + V+ Y ++Y
Sbjct: 42 TLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYG 101
Query: 69 VPVADSPNSRLCDFFDPIADHIHS-VEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSL 127
+ D+P L +F P+A +I + + + QGR L+HCA GVSRSA L LA+LM M+L
Sbjct: 102 IEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTL 161
Query: 128 LDAHTWTKSCRPIIRPNSGFWEQL 151
++A ++ R I PNSGF QL
Sbjct: 162 VEAIQTVQAHRNIC-PNSGFLRQL 184
>gi|56117822 testis and skeletal muscle-specific dual specificity
phosphatase isoform 3 [Homo sapiens]
Length = 291
Score = 72.8 bits (177), Expect = 2e-13
Identities = 50/144 (34%), Positives = 80/144 (55%), Gaps = 9/144 (6%)
Query: 16 SVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVS-----VEVVNTLYE--DIQYMQ 68
+++ + ++ SL++ + AA +K L IT V+N + V+ Y ++Y
Sbjct: 135 TLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYG 194
Query: 69 VPVADSPNSRLCDFFDPIADHIHS-VEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSL 127
+ D+P L +F P+A +I + + + QGR L+HCA GVSRSA L LA+LM M+L
Sbjct: 195 IEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTL 254
Query: 128 LDAHTWTKSCRPIIRPNSGFWEQL 151
++A ++ R I PNSGF QL
Sbjct: 255 VEAIQTVQAHRNIC-PNSGFLRQL 277
>gi|56117820 testis and skeletal muscle-specific dual specificity
phosphatase isoform 2 [Homo sapiens]
Length = 248
Score = 72.8 bits (177), Expect = 2e-13
Identities = 50/144 (34%), Positives = 80/144 (55%), Gaps = 9/144 (6%)
Query: 16 SVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVS-----VEVVNTLYE--DIQYMQ 68
+++ + ++ SL++ + AA +K L IT V+N + V+ Y ++Y
Sbjct: 92 TLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYG 151
Query: 69 VPVADSPNSRLCDFFDPIADHIHS-VEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSL 127
+ D+P L +F P+A +I + + + QGR L+HCA GVSRSA L LA+LM M+L
Sbjct: 152 IEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTL 211
Query: 128 LDAHTWTKSCRPIIRPNSGFWEQL 151
++A ++ R I PNSGF QL
Sbjct: 212 VEAIQTVQAHRNIC-PNSGFLRQL 234
>gi|4503421 dual specificity phosphatase 9 [Homo sapiens]
Length = 384
Score = 72.0 bits (175), Expect = 3e-13
Identities = 50/161 (31%), Positives = 76/161 (47%), Gaps = 7/161 (4%)
Query: 5 SCAFPVQFRQPSVSGLS-----QITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNT 59
SC + P GL QI +LY+ + + N L+ I ++NV+ + N
Sbjct: 184 SCGLDSEGATPPPVGLRASFPVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNF 243
Query: 60 LYE--DIQYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLA 117
+ D Y Q+P++D + L FF + I + L+HC AGVSRS + +A
Sbjct: 244 FEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVA 303
Query: 118 YLMKYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQL 158
YLM+ +SL DA+ K + I PN F QL+ +E L
Sbjct: 304 YLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFERSL 344
>gi|239047414 slingshot 1 isoform 1 [Homo sapiens]
Length = 1049
Score = 70.9 bits (172), Expect = 6e-13
Identities = 43/135 (31%), Positives = 65/135 (48%)
Query: 21 SQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTLYEDIQYMQVPVADSPNSRLC 80
S I LY+ + A+N L + + ++NV+ E+ N Y + V D + L
Sbjct: 310 SLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLL 369
Query: 81 DFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSCRPI 140
++ I+ + + L+HC GVSRSA+ +AY MK L A+ + K R I
Sbjct: 370 AHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSI 429
Query: 141 IRPNSGFWEQLIHYE 155
RPN+GF QL YE
Sbjct: 430 TRPNAGFMRQLSEYE 444
>gi|239047498 slingshot 1 isoform 3 [Homo sapiens]
Length = 703
Score = 70.9 bits (172), Expect = 6e-13
Identities = 43/135 (31%), Positives = 65/135 (48%)
Query: 21 SQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTLYEDIQYMQVPVADSPNSRLC 80
S I LY+ + A+N L + + ++NV+ E+ N Y + V D + L
Sbjct: 321 SLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLL 380
Query: 81 DFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSCRPI 140
++ I+ + + L+HC GVSRSA+ +AY MK L A+ + K R I
Sbjct: 381 AHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSI 440
Query: 141 IRPNSGFWEQLIHYE 155
RPN+GF QL YE
Sbjct: 441 TRPNAGFMRQLSEYE 455
>gi|239047441 slingshot 1 isoform 2 [Homo sapiens]
Length = 692
Score = 70.9 bits (172), Expect = 6e-13
Identities = 43/135 (31%), Positives = 65/135 (48%)
Query: 21 SQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTLYEDIQYMQVPVADSPNSRLC 80
S I LY+ + A+N L + + ++NV+ E+ N Y + V D + L
Sbjct: 310 SLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLL 369
Query: 81 DFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSCRPI 140
++ I+ + + L+HC GVSRSA+ +AY MK L A+ + K R I
Sbjct: 370 AHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSI 429
Query: 141 IRPNSGFWEQLIHYE 155
RPN+GF QL YE
Sbjct: 430 TRPNAGFMRQLSEYE 444
>gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo
sapiens]
Length = 223
Score = 70.5 bits (171), Expect = 8e-13
Identities = 45/141 (31%), Positives = 72/141 (51%), Gaps = 6/141 (4%)
Query: 34 AANNKL-MLSSNQITMVI----NVSVEVVNTLYEDI-QYMQVPVADSPNSRLCDFFDPIA 87
A +KL +L + IT +I N+ + ++ + +Y+ + +AD+P + FF
Sbjct: 44 AMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTK 103
Query: 88 DHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSCRPIIRPNSGF 147
+ I G+ L+H AG+SRSAA +AY+M+ M DA + + R I PN+GF
Sbjct: 104 EFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGF 163
Query: 148 WEQLIHYEFQLFGKNTVHMVS 168
QL YE K T+ M+S
Sbjct: 164 VHQLQEYEAIYLAKLTIQMMS 184
>gi|194733759 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 70.5 bits (171), Expect = 8e-13
Identities = 45/141 (31%), Positives = 72/141 (51%), Gaps = 6/141 (4%)
Query: 34 AANNKL-MLSSNQITMVI----NVSVEVVNTLYEDI-QYMQVPVADSPNSRLCDFFDPIA 87
A +KL +L + IT +I N+ + ++ + +Y+ + +AD+P + FF
Sbjct: 44 AMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTK 103
Query: 88 DHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSCRPIIRPNSGF 147
+ I G+ L+H AG+SRSAA +AY+M+ M DA + + R I PN+GF
Sbjct: 104 EFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGF 163
Query: 148 WEQLIHYEFQLFGKNTVHMVS 168
QL YE K T+ M+S
Sbjct: 164 VHQLQEYEAIYLAKLTIQMMS 184
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.134 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,656,845
Number of Sequences: 37866
Number of extensions: 255200
Number of successful extensions: 686
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 56
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 617
Number of HSP's gapped (non-prelim): 75
length of query: 188
length of database: 18,247,518
effective HSP length: 96
effective length of query: 92
effective length of database: 14,612,382
effective search space: 1344339144
effective search space used: 1344339144
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.