BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|5032295 dystrophin Dp116 isoform [Homo sapiens] (956 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|5032295 dystrophin Dp116 isoform [Homo sapiens] 1928 0.0 gi|5032281 dystrophin Dp427c isoform [Homo sapiens] 1907 0.0 gi|5032291 dystrophin Dp260-2 isoform [Homo sapiens] 1907 0.0 gi|150036268 dystrophin Dp260-1 isoform [Homo sapiens] 1907 0.0 gi|5032315 dystrophin Dp427p2 isoform [Homo sapiens] 1907 0.0 gi|5032287 dystrophin Dp427p1 isoform [Homo sapiens] 1907 0.0 gi|5032293 dystrophin Dp140 isoform [Homo sapiens] 1907 0.0 gi|5032285 dystrophin Dp427l isoform [Homo sapiens] 1907 0.0 gi|5032283 dystrophin Dp427m isoform [Homo sapiens] 1907 0.0 gi|5032309 dystrophin Dp140b isoform [Homo sapiens] 1881 0.0 gi|5032311 dystrophin Dp140ab isoform [Homo sapiens] 1844 0.0 gi|5032313 dystrophin Dp140bc isoform [Homo sapiens] 1363 0.0 gi|5032307 dystrophin Dp140c isoform [Homo sapiens] 1343 0.0 gi|110611228 utrophin [Homo sapiens] 1270 0.0 gi|5032297 dystrophin Dp71 isoform [Homo sapiens] 1240 0.0 gi|5032299 dystrophin Dp71b isoform [Homo sapiens] 1214 0.0 gi|5032301 dystrophin Dp71a isoform [Homo sapiens] 1203 0.0 gi|5032303 dystrophin Dp71ab isoform [Homo sapiens] 1177 0.0 gi|148539558 dystrophin related protein 2 [Homo sapiens] 996 0.0 gi|5032305 dystrophin Dp40 isoform [Homo sapiens] 693 0.0 gi|42717999 dystrobrevin alpha isoform 2 [Homo sapiens] 212 1e-54 gi|42718005 dystrobrevin alpha isoform 1 [Homo sapiens] 206 6e-53 gi|42717997 dystrobrevin alpha isoform 5 [Homo sapiens] 206 6e-53 gi|42718003 dystrobrevin alpha isoform 3 [Homo sapiens] 201 4e-51 gi|42718001 dystrobrevin alpha isoform 4 [Homo sapiens] 199 1e-50 gi|11276069 dystrobrevin, beta isoform 1 [Homo sapiens] 195 2e-49 gi|37577099 dystrobrevin, beta isoform 2 [Homo sapiens] 195 2e-49 gi|37577095 dystrobrevin, beta isoform 4 [Homo sapiens] 195 2e-49 gi|15147341 dystrobrevin, beta isoform 3 [Homo sapiens] 192 1e-48 gi|37577097 dystrobrevin, beta isoform 5 [Homo sapiens] 190 6e-48 >gi|5032295 dystrophin Dp116 isoform [Homo sapiens] Length = 956 Score = 1928 bits (4994), Expect = 0.0 Identities = 956/956 (100%), Positives = 956/956 (100%) Query: 1 MLHRKTYHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSEL 60 MLHRKTYHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSEL Sbjct: 1 MLHRKTYHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSEL 60 Query: 61 RKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHR 120 RKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHR Sbjct: 61 RKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHR 120 Query: 121 AFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAE 180 AFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAE Sbjct: 121 AFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAE 180 Query: 181 EVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLID 240 EVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLID Sbjct: 181 EVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLID 240 Query: 241 SLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQV 300 SLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQV Sbjct: 241 SLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQV 300 Query: 301 AVEDRVRQLHEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMT 360 AVEDRVRQLHEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMT Sbjct: 301 AVEDRVRQLHEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMT 360 Query: 361 ELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQ 420 ELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQ Sbjct: 361 ELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQ 420 Query: 421 IINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKA 480 IINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKA Sbjct: 421 IINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKA 480 Query: 481 HLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQF 540 HLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQF Sbjct: 481 HLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQF 540 Query: 541 ANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSL 600 ANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSL Sbjct: 541 ANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSL 600 Query: 601 KHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKH 660 KHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKH Sbjct: 601 KHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKH 660 Query: 661 PRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMEN 720 PRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMEN Sbjct: 661 PRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMEN 720 Query: 721 SNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERI 780 SNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERI Sbjct: 721 SNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERI 780 Query: 781 LADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHK 840 LADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHK Sbjct: 781 LADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHK 840 Query: 841 GRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLL 900 GRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLL Sbjct: 841 GRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLL 900 Query: 901 RVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM 956 RVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM Sbjct: 901 RVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM 956 >gi|5032281 dystrophin Dp427c isoform [Homo sapiens] Length = 3677 Score = 1907 bits (4939), Expect = 0.0 Identities = 946/947 (99%), Positives = 947/947 (100%) Query: 10 KDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 69 +DLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS Sbjct: 2731 QDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 2790 Query: 70 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 129 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK Sbjct: 2791 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 2850 Query: 130 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL 189 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL Sbjct: 2851 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL 2910 Query: 190 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV 249 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV Sbjct: 2911 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV 2970 Query: 250 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL 309 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL Sbjct: 2971 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL 3030 Query: 310 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 369 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL Sbjct: 3031 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 3090 Query: 370 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 429 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY Sbjct: 3091 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 3150 Query: 430 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL 489 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL Sbjct: 3151 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL 3210 Query: 490 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA 549 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA Sbjct: 3211 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA 3270 Query: 550 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ 609 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ Sbjct: 3271 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ 3330 Query: 610 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ 669 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ Sbjct: 3331 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ 3390 Query: 670 TVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS 729 TVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS Sbjct: 3391 TVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS 3450 Query: 730 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENR 789 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENR Sbjct: 3451 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENR 3510 Query: 790 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI 849 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI Sbjct: 3511 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI 3570 Query: 850 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD 909 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD Sbjct: 3571 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD 3630 Query: 910 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM 956 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM Sbjct: 3631 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM 3677 Score = 67.8 bits (164), Expect = 5e-11 Identities = 53/235 (22%), Positives = 99/235 (42%), Gaps = 33/235 (14%) Query: 87 ELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTE 146 EL WL L D + Q + GD + + +A ++L+ + P Sbjct: 2473 ELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQ-------------- 2518 Query: 147 QPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLER 206 LE+L + L + Q ++ + E + +W+++ H + +++++E L+ Sbjct: 2519 -----LEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKD 2573 Query: 207 LQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHV 266 + EA +E + L QA SW+ G +D++Q + + K L ++ + NV Sbjct: 2574 STQWLEAKEEAEQVLGQARAKLESWKE-GPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 2632 Query: 267 NDLARQLTTLGIQLSPYNLSTL-------EDLNTRWKLLQVAVEDRVRQLHEAHR 314 NDLA +L L Y+ E++N W+ + V +R L E HR Sbjct: 2633 NDLALKL------LRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHR 2681 Score = 60.5 bits (145), Expect = 7e-09 Identities = 79/375 (21%), Positives = 152/375 (40%), Gaps = 34/375 (9%) Query: 7 YHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLN 66 +++K+LQ I V L+ ++I++ DA +LQ +L ++N +W E+ K+ + Sbjct: 2135 WYLKELQDGIGQRQTVVRTLNATGEEIIQQ-SSKTDASILQEKLGSLNLRWQEVCKQLSD 2193 Query: 67 IRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKREL 126 + LE + L E ++WL+ D+ S G + +K V + EL Sbjct: 2194 RKKRLEEQKNILSEFQRDLNEFVLWLEEADNIASIPLEPGKEQQLKEKLEQV-KLLVEEL 2252 Query: 127 KTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEW 186 ++ ++ ET L P+ PEE+ + L + ++ N +W Sbjct: 2253 PLRQGILKQLNETGGPVLVSAPIS-------------PEEQDK-----LENKLKQTNLQW 2294 Query: 187 EKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHL 246 K++ + Q +I+ ++ L +L++ ++L+ +L + + ++ Q+ Sbjct: 2295 IKVSRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHLLLWLSPIRNQLEIYNQPNQEGP 2354 Query: 247 EKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRV 306 V+ + + +V + + L P LEDL++ WK AV + Sbjct: 2355 FDVQETEIAVQAKQPDVEEILSKGQHLYKEKPATQPVK-RKLEDLSSEWK----AVNRLL 2409 Query: 307 RQLHEAHRDFGP------ASQHFLSTSVQGP---WERAISPNKVPYYINHETQTTCWDHP 357 ++L D P AS T V P E AIS ++P + E + Sbjct: 2410 QELRAKQPDLAPGLTTIGASPTQTVTLVTQPVVTKETAISKLEMPSSLMLEVPALADFNR 2469 Query: 358 KMTELYQSLADLNNV 372 TEL L+ L+ V Sbjct: 2470 AWTELTDWLSLLDQV 2484 Score = 56.2 bits (134), Expect = 1e-07 Identities = 62/314 (19%), Positives = 132/314 (42%), Gaps = 33/314 (10%) Query: 8 HVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNI 67 ++KD + D+ H+ + + +E V LQ L ++F+W ++ K + Sbjct: 2032 NIKDSLQQSSGRIDIIHSKKTAALQSATPVE----RVKLQEALSQLDFQWEKVNKMYKDR 2087 Query: 68 RSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELK 127 + + S ++W+R H ++ WL + ++ R+ I +N H +K LK Sbjct: 2088 QGRFDRSVEKWRRFHYDIKIFNQWL-TEAEQFLRKTQI--------PENWEHAKYKWYLK 2138 Query: 128 TKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWE 187 + I VR E++ Q + ++ +L+++ +N W+ Sbjct: 2139 ELQDGIGQRQTVVRTLNATG-----EEIIQ--------QSSKTDASILQEKLGSLNLRWQ 2185 Query: 188 KLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLE 247 ++ +D +++++E L E Q +E L L +A+ I P+ L++ LE Sbjct: 2186 EVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEADNIASI--PLEPGKEQQLKEKLE 2243 Query: 248 KVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLED----LNTRWKLLQVAVE 303 +VK L E+ PL++ + + + +SP LE+ N +W + A+ Sbjct: 2244 QVKLLVEEL-PLRQGILKQLNETGGPVLVSAPISPEEQDKLENKLKQTNLQWIKVSRALP 2302 Query: 304 DRVRQLHEAHRDFG 317 ++ ++ +D G Sbjct: 2303 EKQGEIEAQIKDLG 2316 Score = 53.9 bits (128), Expect = 7e-07 Identities = 64/312 (20%), Positives = 130/312 (41%), Gaps = 26/312 (8%) Query: 1 MLHRKTYHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSEL 60 +L ++ + L +I+ ++++E QKI E + A L+ L +N +W + Sbjct: 1075 ILKKQLKQCRLLVSDIQTIQPSLNSVNEGGQKIKNEAE-PEFASRLETELKELNTQWDHM 1133 Query: 61 RKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHR 120 ++ + L+ ++ L L E+ W+ ++E + +QK + + Sbjct: 1134 CQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEEEYLERDFEYKTPDELQKAVEEMK 1193 Query: 121 AFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAE 180 K E + KE + E+V + + P E L +E + +T + Sbjct: 1194 RAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEALKKE---------LETLTTNYQWLCT 1244 Query: 181 EVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLID 240 +N + + L A W E L L++ + +E++ KL+ E I G + + ++L D Sbjct: 1245 RLNGKCKTLEEVWACWH----ELLSYLEKANKWLNEVEFKLKTTENIPGGAEEISEVL-D 1299 Query: 241 SLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQV 300 SL++ + ++N + + LA+ LT G+ N LE N+RW+ L Sbjct: 1300 SLENLMRH----------SEDNPNQIRILAQTLTDGGVMDELIN-EELETFNSRWRELHE 1348 Query: 301 AVEDRVRQLHEA 312 R + L ++ Sbjct: 1349 EAVRRQKLLEQS 1360 Score = 50.4 bits (119), Expect = 8e-06 Identities = 38/164 (23%), Positives = 85/164 (51%), Gaps = 6/164 (3%) Query: 134 MSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHS 193 + L+ ++ L EQ GL L +E+ + ++ ++R + + EE+ W+KL+ Sbjct: 971 LGELQALQSSLQEQQ-SGLYYLSTTVKEMSKKAPSE-ISRKYQSEFEEIEGRWKKLSSQL 1028 Query: 194 ADWQRKIDETLERLQELQEATDELDLKLRQAEV-IKGSWQPVGDLLIDSLQDHLEKVKAL 252 + +K++E + +L+++Q L + + +V +K W +GD I L+ L++ + L Sbjct: 1029 VEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEWPALGDSEI--LKKQLKQCRLL 1086 Query: 253 RGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLST-LEDLNTRW 295 +I ++ +++ VN+ +++ L T L++LNT+W Sbjct: 1087 VSDIQTIQPSLNSVNEGGQKIKNEAEPEFASRLETELKELNTQW 1130 Score = 47.4 bits (111), Expect = 7e-05 Identities = 68/315 (21%), Positives = 125/315 (39%), Gaps = 53/315 (16%) Query: 17 EAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS-----HL 71 E H ++H + + Q + +G + + R + + + S RS HL Sbjct: 255 EEHFQLHHQMHYSQQITVSLAQGYERTSSPKPRFKSYAYTQAAYVTTSDPTRSPFPSQHL 314 Query: 72 EASSDQ------------WKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVH 119 EA D+ R +L+E+L WL +D L Q I D V+ Q H Sbjct: 315 EAPEDKSFGSSLMESEVNLDRYQTALEEVLSWLLSAEDTLQAQGEISNDVEVVKDQFHTH 374 Query: 120 RAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQA 179 + +L + + + L+ L G KL ++ EE +++Q Sbjct: 375 EGYMMDLTAHQGRVGNILQ------LGSKLIGTGKLSED------EETE------VQEQM 416 Query: 180 EEVNTEWEKLNLHSADWQRKIDETL-----ERLQELQEATDELDLKLRQAEVIKGSWQPV 234 +N+ WE L + S + Q + L ++L+EL + + + + R+ E +P+ Sbjct: 417 NLLNSRWECLRVASMEKQSNLHRVLMDLQNQKLKELNDWLTKTEERTRKMEE-----EPL 471 Query: 235 GDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLED---- 290 G L D L+ +++ K L+ + L++ VN L + + + + LE+ Sbjct: 472 GPDLED-LKRQVQQHKVLQED---LEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKV 527 Query: 291 LNTRWKLLQVAVEDR 305 L RW + EDR Sbjct: 528 LGDRWANICRWTEDR 542 Score = 42.4 bits (98), Expect = 0.002 Identities = 53/268 (19%), Positives = 109/268 (40%), Gaps = 26/268 (9%) Query: 47 QRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIG 106 Q + + +W +L + + LE ++ +++ +Q L W+ D L + P Sbjct: 1011 QSEFEEIEGRWKKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEWPAL 1070 Query: 107 GDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEE 166 GD ++KQ R +++T +P + S EG +K+ E PE Sbjct: 1071 GDSEILKKQLKQCRLLVSDIQTIQPSLNSV------------NEGGQKI---KNEAEPEF 1115 Query: 167 RAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQA-- 224 ++ L + +E+NT+W+ + + + LE+ LQ+ E+ + QA Sbjct: 1116 ASR-----LETELKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEE 1170 Query: 225 EVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYN 284 E ++ ++ D LQ +E++K + E + V + + + ++ Sbjct: 1171 EYLERDFEYKTP---DELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEA 1227 Query: 285 L-STLEDLNTRWKLLQVAVEDRVRQLHE 311 L LE L T ++ L + + + L E Sbjct: 1228 LKKELETLTTNYQWLCTRLNGKCKTLEE 1255 Score = 40.0 bits (92), Expect = 0.010 Identities = 70/329 (21%), Positives = 138/329 (41%), Gaps = 52/329 (15%) Query: 10 KDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 69 KDL+ + + + DV ++L + K+LR +DD + +N+N W + K+ + Sbjct: 2620 KDLR-QWQTNVDVANDL---ALKLLRDYS-ADDTRKVHMITENINASWRSIHKRVSEREA 2674 Query: 70 HLEASSDQWKRLHLSLQELLVWLQLKD------DELSRQAPIGGDFPAVQKQNDVHRAFK 123 LE + ++ L L++ L WL + + +R+ + D V++ + + Sbjct: 2675 ALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQ 2734 Query: 124 RELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELP------PEERAQNVTRLLRK 177 E++ V + E + L + LEG + R L E R +++ +R Sbjct: 2735 GEIEAHTDVYHNLDENSQKIL--RSLEGSDDAVLLQRRLDNMNFKWSELRKKSLN--IRS 2790 Query: 178 QAEEVNTEWEKLNLHSAD---WQRKIDETLER-------LQELQEATD-----ELDLKLR 222 E + +W++L+L + W + D+ L R +Q+ D + +LK + Sbjct: 2791 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 2850 Query: 223 QAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSP 282 + VI + + V L + + LEK+ E+ P +E +V L R+ Sbjct: 2851 E-PVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPP-EERAQNVTRLLRK---------- 2898 Query: 283 YNLSTLEDLNTRWKLLQVAVEDRVRQLHE 311 E++NT W+ L + D R++ E Sbjct: 2899 ----QAEEVNTEWEKLNLHSADWQRKIDE 2923 Score = 38.5 bits (88), Expect = 0.030 Identities = 111/514 (21%), Positives = 190/514 (36%), Gaps = 59/514 (11%) Query: 2 LHRKTYHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGS-DDAVLLQRRLDNMNFKWSEL 60 L K VK L E+ + L+E +L S S ++ L+ +L N +W ++ Sbjct: 2238 LKEKLEQVKLLVEELPLRQGILKQLNETGGPVLVSAPISPEEQDKLENKLKQTNLQWIKV 2297 Query: 61 RKKSLNIRSHLEASSDQWKRLHLSLQEL-------LVWLQLKDDELS--RQAPIGGDFP- 110 + + +EA +L L++L L+WL ++L Q G F Sbjct: 2298 SRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHLLLWLSPIRNQLEIYNQPNQEGPFDV 2357 Query: 111 -----AVQ-KQNDVHRAFKR--ELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPREL 162 AVQ KQ DV + L ++P + +E + + +L QE R Sbjct: 2358 QETEIAVQAKQPDVEEILSKGQHLYKEKPATQPVKRKLEDLSSEW--KAVNRLLQELRAK 2415 Query: 163 PPE----------ERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQE 212 P+ Q VT L+ + T KL + S+ ++ + + E Sbjct: 2416 QPDLAPGLTTIGASPTQTVT-LVTQPVVTKETAISKLEMPSS-LMLEVPALADFNRAWTE 2473 Query: 213 ATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQ 272 TD L L +VIK VGDL + + + + K KA ++ + + + A+ Sbjct: 2474 LTDWLSLL---DQVIKSQRVMVGDL--EDINEMIIKQKATMQDLEQRRPQLEELITAAQN 2528 Query: 273 LTTLGIQLSPYNLST--LEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQG 330 L + T +E + +W +Q +++R +QL+E +D S +L + Sbjct: 2529 LKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKD----STQWLEAKEEA 2584 Query: 331 PWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKAL 390 + K+ + T K+TE Q DL + + + L Sbjct: 2585 EQVLGQARAKLESW-KEGPYTVDAIQKKITETKQLAKDLRQWQTNV--------DVANDL 2635 Query: 391 CLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCL 450 L LL +A D H + +N I ++ LE+ H L PL ++ L Sbjct: 2636 ALKLLRDYSADDTRKVHMITENINA-SWRSIHKRVSEREAALEETHRLLQQFPLDLEKFL 2694 Query: 451 NWLLNVYDTGR-----TGRIRVLSFKTGIISLCK 479 WL T T + R+L G+ L K Sbjct: 2695 AWLTEAETTANVLQDATRKERLLEDSKGVKELMK 2728 Score = 35.0 bits (79), Expect = 0.33 Identities = 41/178 (23%), Positives = 78/178 (43%), Gaps = 10/178 (5%) Query: 715 LAEMENSNGSYLNDS-ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEE 773 L ++ + G L + ISP E E+ L Q Q + L + + I + ++ Sbjct: 2259 LKQLNETGGPVLVSAPISPEEQDKLENKLKQTNLQWIKVSRALPEKQGE----IEAQIKD 2314 Query: 774 RGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPT----SPQSPRDAEL 829 G+LE+ L DLEE+ +L ++ Q E P ++ T + P E+ Sbjct: 2315 LGQLEKKLEDLEEQLNHLLLWLSPIRNQLEIYNQPNQEGPFDVQETEIAVQAKQPDVEEI 2374 Query: 830 IAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPST 887 +++ + L + K + + LED + + ++ ++RL Q L Q + TT+ + T Sbjct: 2375 LSKGQHLYKEKPATQPVKRKLEDLSSEWKA-VNRLLQELRAKQPDLAPGLTTIGASPT 2431 Score = 32.3 bits (72), Expect = 2.2 Identities = 45/281 (16%), Positives = 104/281 (37%), Gaps = 36/281 (12%) Query: 2 LHRKTYHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVL---------LQRRLDN 52 L K+ + +Q ++ ++Y +L E ++ ++ V L R+ Sbjct: 1480 LETKSVEQEVVQSQLNHCVNLYKSLSEVKSEVEMVIKTGRQIVQKKQTENPKELDERVTA 1539 Query: 53 MNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAV 112 + ++EL K + LE +++ + L WL D EL++++ + G + Sbjct: 1540 LKLHYNELGAKVTERKQQLEKCLKLSRKMRKEMNVLTEWLAATDMELTKRSAVEGMPSNL 1599 Query: 113 QKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVT 172 + +A ++E++ ++ + S E T L E L ++ L Sbjct: 1600 DSEVAWGKATQKEIEKQKVHLKSITEVGEALKTV--LGKKETLVEDKLSL---------- 1647 Query: 173 RLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQ 232 +N+ W + + +W + E + ++ + D + + QA+ + + Sbjct: 1648 ---------LNSNWIAVTSRAEEWLNLLLEYQKHMETFDQNVDHITKWIIQADTLLDESE 1698 Query: 233 PVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQL 273 Q + +K L+ E+ ++ V D A L Sbjct: 1699 K------KKPQQKEDVLKRLKAELNDIRPKVDSTRDQAANL 1733 Score = 31.6 bits (70), Expect = 3.7 Identities = 42/234 (17%), Positives = 97/234 (41%), Gaps = 34/234 (14%) Query: 1 MLHRKTYHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSEL 60 +L R + D++ ++++ D NL N G L++ ++ +N +++ + Sbjct: 1708 VLKRLKAELNDIRPKVDSTRDQAANLMAN--------RGDHCRKLVEPQISELNHRFAAI 1759 Query: 61 R------KKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQK 114 K S+ ++ + +SD K L E+ + LK+++ ++ Sbjct: 1760 SHRIKTGKASIPLKELEQFNSDIQKLLEPLEAEIQQGVNLKEEDFNKD------------ 1807 Query: 115 QNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRL 174 N+ + +EL + + + R + ++ ++L Q + R+Q Sbjct: 1808 MNEDNEGTVKELLQRGDNLQQRITDER---KREEIKIKQQLLQTKHNALKDLRSQR---- 1860 Query: 175 LRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIK 228 RK+A E++ +W + + D + +D+ ++L L E DE +K E+ K Sbjct: 1861 -RKKALEISHQWYQYKRQADDLLKCLDDIEKKLASLPEPRDERKIKEIDRELQK 1913 >gi|5032291 dystrophin Dp260-2 isoform [Homo sapiens] Length = 2341 Score = 1907 bits (4939), Expect = 0.0 Identities = 946/947 (99%), Positives = 947/947 (100%) Query: 10 KDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 69 +DLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS Sbjct: 1395 QDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 1454 Query: 70 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 129 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK Sbjct: 1455 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 1514 Query: 130 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL 189 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL Sbjct: 1515 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL 1574 Query: 190 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV 249 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV Sbjct: 1575 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV 1634 Query: 250 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL 309 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL Sbjct: 1635 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL 1694 Query: 310 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 369 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL Sbjct: 1695 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 1754 Query: 370 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 429 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY Sbjct: 1755 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 1814 Query: 430 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL 489 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL Sbjct: 1815 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL 1874 Query: 490 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA 549 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA Sbjct: 1875 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA 1934 Query: 550 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ 609 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ Sbjct: 1935 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ 1994 Query: 610 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ 669 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ Sbjct: 1995 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ 2054 Query: 670 TVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS 729 TVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS Sbjct: 2055 TVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS 2114 Query: 730 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENR 789 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENR Sbjct: 2115 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENR 2174 Query: 790 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI 849 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI Sbjct: 2175 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI 2234 Query: 850 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD 909 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD Sbjct: 2235 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD 2294 Query: 910 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM 956 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM Sbjct: 2295 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM 2341 Score = 67.8 bits (164), Expect = 5e-11 Identities = 53/235 (22%), Positives = 99/235 (42%), Gaps = 33/235 (14%) Query: 87 ELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTE 146 EL WL L D + Q + GD + + +A ++L+ + P Sbjct: 1137 ELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQ-------------- 1182 Query: 147 QPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLER 206 LE+L + L + Q ++ + E + +W+++ H + +++++E L+ Sbjct: 1183 -----LEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKD 1237 Query: 207 LQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHV 266 + EA +E + L QA SW+ G +D++Q + + K L ++ + NV Sbjct: 1238 STQWLEAKEEAEQVLGQARAKLESWKE-GPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 1296 Query: 267 NDLARQLTTLGIQLSPYNLSTL-------EDLNTRWKLLQVAVEDRVRQLHEAHR 314 NDLA +L L Y+ E++N W+ + V +R L E HR Sbjct: 1297 NDLALKL------LRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHR 1345 Score = 60.5 bits (145), Expect = 7e-09 Identities = 79/375 (21%), Positives = 152/375 (40%), Gaps = 34/375 (9%) Query: 7 YHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLN 66 +++K+LQ I V L+ ++I++ DA +LQ +L ++N +W E+ K+ + Sbjct: 799 WYLKELQDGIGQRQTVVRTLNATGEEIIQQ-SSKTDASILQEKLGSLNLRWQEVCKQLSD 857 Query: 67 IRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKREL 126 + LE + L E ++WL+ D+ S G + +K V + EL Sbjct: 858 RKKRLEEQKNILSEFQRDLNEFVLWLEEADNIASIPLEPGKEQQLKEKLEQV-KLLVEEL 916 Query: 127 KTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEW 186 ++ ++ ET L P+ PEE+ + L + ++ N +W Sbjct: 917 PLRQGILKQLNETGGPVLVSAPIS-------------PEEQDK-----LENKLKQTNLQW 958 Query: 187 EKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHL 246 K++ + Q +I+ ++ L +L++ ++L+ +L + + ++ Q+ Sbjct: 959 IKVSRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHLLLWLSPIRNQLEIYNQPNQEGP 1018 Query: 247 EKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRV 306 V+ + + +V + + L P LEDL++ WK AV + Sbjct: 1019 FDVQETEIAVQAKQPDVEEILSKGQHLYKEKPATQPVK-RKLEDLSSEWK----AVNRLL 1073 Query: 307 RQLHEAHRDFGP------ASQHFLSTSVQGP---WERAISPNKVPYYINHETQTTCWDHP 357 ++L D P AS T V P E AIS ++P + E + Sbjct: 1074 QELRAKQPDLAPGLTTIGASPTQTVTLVTQPVVTKETAISKLEMPSSLMLEVPALADFNR 1133 Query: 358 KMTELYQSLADLNNV 372 TEL L+ L+ V Sbjct: 1134 AWTELTDWLSLLDQV 1148 Score = 56.2 bits (134), Expect = 1e-07 Identities = 62/314 (19%), Positives = 132/314 (42%), Gaps = 33/314 (10%) Query: 8 HVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNI 67 ++KD + D+ H+ + + +E V LQ L ++F+W ++ K + Sbjct: 696 NIKDSLQQSSGRIDIIHSKKTAALQSATPVE----RVKLQEALSQLDFQWEKVNKMYKDR 751 Query: 68 RSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELK 127 + + S ++W+R H ++ WL + ++ R+ I +N H +K LK Sbjct: 752 QGRFDRSVEKWRRFHYDIKIFNQWL-TEAEQFLRKTQI--------PENWEHAKYKWYLK 802 Query: 128 TKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWE 187 + I VR E++ Q + ++ +L+++ +N W+ Sbjct: 803 ELQDGIGQRQTVVRTLNATG-----EEIIQ--------QSSKTDASILQEKLGSLNLRWQ 849 Query: 188 KLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLE 247 ++ +D +++++E L E Q +E L L +A+ I P+ L++ LE Sbjct: 850 EVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEADNIASI--PLEPGKEQQLKEKLE 907 Query: 248 KVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLED----LNTRWKLLQVAVE 303 +VK L E+ PL++ + + + +SP LE+ N +W + A+ Sbjct: 908 QVKLLVEEL-PLRQGILKQLNETGGPVLVSAPISPEEQDKLENKLKQTNLQWIKVSRALP 966 Query: 304 DRVRQLHEAHRDFG 317 ++ ++ +D G Sbjct: 967 EKQGEIEAQIKDLG 980 Score = 40.0 bits (92), Expect = 0.010 Identities = 70/329 (21%), Positives = 138/329 (41%), Gaps = 52/329 (15%) Query: 10 KDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 69 KDL+ + + + DV ++L + K+LR +DD + +N+N W + K+ + Sbjct: 1284 KDLR-QWQTNVDVANDL---ALKLLRDYS-ADDTRKVHMITENINASWRSIHKRVSEREA 1338 Query: 70 HLEASSDQWKRLHLSLQELLVWLQLKD------DELSRQAPIGGDFPAVQKQNDVHRAFK 123 LE + ++ L L++ L WL + + +R+ + D V++ + + Sbjct: 1339 ALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQ 1398 Query: 124 RELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELP------PEERAQNVTRLLRK 177 E++ V + E + L + LEG + R L E R +++ +R Sbjct: 1399 GEIEAHTDVYHNLDENSQKIL--RSLEGSDDAVLLQRRLDNMNFKWSELRKKSLN--IRS 1454 Query: 178 QAEEVNTEWEKLNLHSAD---WQRKIDETLER-------LQELQEATD-----ELDLKLR 222 E + +W++L+L + W + D+ L R +Q+ D + +LK + Sbjct: 1455 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 1514 Query: 223 QAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSP 282 + VI + + V L + + LEK+ E+ P +E +V L R+ Sbjct: 1515 E-PVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPP-EERAQNVTRLLRK---------- 1562 Query: 283 YNLSTLEDLNTRWKLLQVAVEDRVRQLHE 311 E++NT W+ L + D R++ E Sbjct: 1563 ----QAEEVNTEWEKLNLHSADWQRKIDE 1587 Score = 38.5 bits (88), Expect = 0.030 Identities = 111/514 (21%), Positives = 190/514 (36%), Gaps = 59/514 (11%) Query: 2 LHRKTYHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGS-DDAVLLQRRLDNMNFKWSEL 60 L K VK L E+ + L+E +L S S ++ L+ +L N +W ++ Sbjct: 902 LKEKLEQVKLLVEELPLRQGILKQLNETGGPVLVSAPISPEEQDKLENKLKQTNLQWIKV 961 Query: 61 RKKSLNIRSHLEASSDQWKRLHLSLQEL-------LVWLQLKDDELS--RQAPIGGDFP- 110 + + +EA +L L++L L+WL ++L Q G F Sbjct: 962 SRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHLLLWLSPIRNQLEIYNQPNQEGPFDV 1021 Query: 111 -----AVQ-KQNDVHRAFKR--ELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPREL 162 AVQ KQ DV + L ++P + +E + + +L QE R Sbjct: 1022 QETEIAVQAKQPDVEEILSKGQHLYKEKPATQPVKRKLEDLSSEW--KAVNRLLQELRAK 1079 Query: 163 PPE----------ERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQE 212 P+ Q VT L+ + T KL + S+ ++ + + E Sbjct: 1080 QPDLAPGLTTIGASPTQTVT-LVTQPVVTKETAISKLEMPSS-LMLEVPALADFNRAWTE 1137 Query: 213 ATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQ 272 TD L L +VIK VGDL + + + + K KA ++ + + + A+ Sbjct: 1138 LTDWLSLL---DQVIKSQRVMVGDL--EDINEMIIKQKATMQDLEQRRPQLEELITAAQN 1192 Query: 273 LTTLGIQLSPYNLST--LEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQG 330 L + T +E + +W +Q +++R +QL+E +D S +L + Sbjct: 1193 LKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKD----STQWLEAKEEA 1248 Query: 331 PWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKAL 390 + K+ + T K+TE Q DL + + + L Sbjct: 1249 EQVLGQARAKLESW-KEGPYTVDAIQKKITETKQLAKDLRQWQTNV--------DVANDL 1299 Query: 391 CLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCL 450 L LL +A D H + +N I ++ LE+ H L PL ++ L Sbjct: 1300 ALKLLRDYSADDTRKVHMITENINA-SWRSIHKRVSEREAALEETHRLLQQFPLDLEKFL 1358 Query: 451 NWLLNVYDTGR-----TGRIRVLSFKTGIISLCK 479 WL T T + R+L G+ L K Sbjct: 1359 AWLTEAETTANVLQDATRKERLLEDSKGVKELMK 1392 Score = 35.0 bits (79), Expect = 0.33 Identities = 41/178 (23%), Positives = 78/178 (43%), Gaps = 10/178 (5%) Query: 715 LAEMENSNGSYLNDS-ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEE 773 L ++ + G L + ISP E E+ L Q Q + L + + I + ++ Sbjct: 923 LKQLNETGGPVLVSAPISPEEQDKLENKLKQTNLQWIKVSRALPEKQGE----IEAQIKD 978 Query: 774 RGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPT----SPQSPRDAEL 829 G+LE+ L DLEE+ +L ++ Q E P ++ T + P E+ Sbjct: 979 LGQLEKKLEDLEEQLNHLLLWLSPIRNQLEIYNQPNQEGPFDVQETEIAVQAKQPDVEEI 1038 Query: 830 IAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPST 887 +++ + L + K + + LED + + ++ ++RL Q L Q + TT+ + T Sbjct: 1039 LSKGQHLYKEKPATQPVKRKLEDLSSEWKA-VNRLLQELRAKQPDLAPGLTTIGASPT 1095 Score = 32.3 bits (72), Expect = 2.2 Identities = 45/281 (16%), Positives = 104/281 (37%), Gaps = 36/281 (12%) Query: 2 LHRKTYHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVL---------LQRRLDN 52 L K+ + +Q ++ ++Y +L E ++ ++ V L R+ Sbjct: 144 LETKSVEQEVVQSQLNHCVNLYKSLSEVKSEVEMVIKTGRQIVQKKQTENPKELDERVTA 203 Query: 53 MNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAV 112 + ++EL K + LE +++ + L WL D EL++++ + G + Sbjct: 204 LKLHYNELGAKVTERKQQLEKCLKLSRKMRKEMNVLTEWLAATDMELTKRSAVEGMPSNL 263 Query: 113 QKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVT 172 + +A ++E++ ++ + S E T L E L ++ L Sbjct: 264 DSEVAWGKATQKEIEKQKVHLKSITEVGEALKTV--LGKKETLVEDKLSL---------- 311 Query: 173 RLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQ 232 +N+ W + + +W + E + ++ + D + + QA+ + + Sbjct: 312 ---------LNSNWIAVTSRAEEWLNLLLEYQKHMETFDQNVDHITKWIIQADTLLDESE 362 Query: 233 PVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQL 273 Q + +K L+ E+ ++ V D A L Sbjct: 363 K------KKPQQKEDVLKRLKAELNDIRPKVDSTRDQAANL 397 Score = 31.6 bits (70), Expect = 3.7 Identities = 42/234 (17%), Positives = 97/234 (41%), Gaps = 34/234 (14%) Query: 1 MLHRKTYHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSEL 60 +L R + D++ ++++ D NL N G L++ ++ +N +++ + Sbjct: 372 VLKRLKAELNDIRPKVDSTRDQAANLMAN--------RGDHCRKLVEPQISELNHRFAAI 423 Query: 61 R------KKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQK 114 K S+ ++ + +SD K L E+ + LK+++ ++ Sbjct: 424 SHRIKTGKASIPLKELEQFNSDIQKLLEPLEAEIQQGVNLKEEDFNKD------------ 471 Query: 115 QNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRL 174 N+ + +EL + + + R + ++ ++L Q + R+Q Sbjct: 472 MNEDNEGTVKELLQRGDNLQQRITDER---KREEIKIKQQLLQTKHNALKDLRSQR---- 524 Query: 175 LRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIK 228 RK+A E++ +W + + D + +D+ ++L L E DE +K E+ K Sbjct: 525 -RKKALEISHQWYQYKRQADDLLKCLDDIEKKLASLPEPRDERKIKEIDRELQK 577 >gi|150036268 dystrophin Dp260-1 isoform [Homo sapiens] Length = 2344 Score = 1907 bits (4939), Expect = 0.0 Identities = 946/947 (99%), Positives = 947/947 (100%) Query: 10 KDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 69 +DLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS Sbjct: 1398 QDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 1457 Query: 70 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 129 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK Sbjct: 1458 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 1517 Query: 130 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL 189 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL Sbjct: 1518 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL 1577 Query: 190 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV 249 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV Sbjct: 1578 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV 1637 Query: 250 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL 309 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL Sbjct: 1638 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL 1697 Query: 310 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 369 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL Sbjct: 1698 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 1757 Query: 370 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 429 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY Sbjct: 1758 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 1817 Query: 430 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL 489 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL Sbjct: 1818 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL 1877 Query: 490 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA 549 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA Sbjct: 1878 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA 1937 Query: 550 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ 609 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ Sbjct: 1938 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ 1997 Query: 610 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ 669 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ Sbjct: 1998 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ 2057 Query: 670 TVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS 729 TVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS Sbjct: 2058 TVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS 2117 Query: 730 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENR 789 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENR Sbjct: 2118 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENR 2177 Query: 790 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI 849 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI Sbjct: 2178 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI 2237 Query: 850 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD 909 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD Sbjct: 2238 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD 2297 Query: 910 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM 956 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM Sbjct: 2298 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM 2344 Score = 67.8 bits (164), Expect = 5e-11 Identities = 53/235 (22%), Positives = 99/235 (42%), Gaps = 33/235 (14%) Query: 87 ELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTE 146 EL WL L D + Q + GD + + +A ++L+ + P Sbjct: 1140 ELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQ-------------- 1185 Query: 147 QPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLER 206 LE+L + L + Q ++ + E + +W+++ H + +++++E L+ Sbjct: 1186 -----LEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKD 1240 Query: 207 LQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHV 266 + EA +E + L QA SW+ G +D++Q + + K L ++ + NV Sbjct: 1241 STQWLEAKEEAEQVLGQARAKLESWKE-GPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 1299 Query: 267 NDLARQLTTLGIQLSPYNLSTL-------EDLNTRWKLLQVAVEDRVRQLHEAHR 314 NDLA +L L Y+ E++N W+ + V +R L E HR Sbjct: 1300 NDLALKL------LRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHR 1348 Score = 60.5 bits (145), Expect = 7e-09 Identities = 79/375 (21%), Positives = 152/375 (40%), Gaps = 34/375 (9%) Query: 7 YHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLN 66 +++K+LQ I V L+ ++I++ DA +LQ +L ++N +W E+ K+ + Sbjct: 802 WYLKELQDGIGQRQTVVRTLNATGEEIIQQ-SSKTDASILQEKLGSLNLRWQEVCKQLSD 860 Query: 67 IRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKREL 126 + LE + L E ++WL+ D+ S G + +K V + EL Sbjct: 861 RKKRLEEQKNILSEFQRDLNEFVLWLEEADNIASIPLEPGKEQQLKEKLEQV-KLLVEEL 919 Query: 127 KTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEW 186 ++ ++ ET L P+ PEE+ + L + ++ N +W Sbjct: 920 PLRQGILKQLNETGGPVLVSAPIS-------------PEEQDK-----LENKLKQTNLQW 961 Query: 187 EKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHL 246 K++ + Q +I+ ++ L +L++ ++L+ +L + + ++ Q+ Sbjct: 962 IKVSRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHLLLWLSPIRNQLEIYNQPNQEGP 1021 Query: 247 EKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRV 306 V+ + + +V + + L P LEDL++ WK AV + Sbjct: 1022 FDVQETEIAVQAKQPDVEEILSKGQHLYKEKPATQPVK-RKLEDLSSEWK----AVNRLL 1076 Query: 307 RQLHEAHRDFGP------ASQHFLSTSVQGP---WERAISPNKVPYYINHETQTTCWDHP 357 ++L D P AS T V P E AIS ++P + E + Sbjct: 1077 QELRAKQPDLAPGLTTIGASPTQTVTLVTQPVVTKETAISKLEMPSSLMLEVPALADFNR 1136 Query: 358 KMTELYQSLADLNNV 372 TEL L+ L+ V Sbjct: 1137 AWTELTDWLSLLDQV 1151 Score = 56.2 bits (134), Expect = 1e-07 Identities = 62/314 (19%), Positives = 132/314 (42%), Gaps = 33/314 (10%) Query: 8 HVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNI 67 ++KD + D+ H+ + + +E V LQ L ++F+W ++ K + Sbjct: 699 NIKDSLQQSSGRIDIIHSKKTAALQSATPVE----RVKLQEALSQLDFQWEKVNKMYKDR 754 Query: 68 RSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELK 127 + + S ++W+R H ++ WL + ++ R+ I +N H +K LK Sbjct: 755 QGRFDRSVEKWRRFHYDIKIFNQWL-TEAEQFLRKTQI--------PENWEHAKYKWYLK 805 Query: 128 TKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWE 187 + I VR E++ Q + ++ +L+++ +N W+ Sbjct: 806 ELQDGIGQRQTVVRTLNATG-----EEIIQ--------QSSKTDASILQEKLGSLNLRWQ 852 Query: 188 KLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLE 247 ++ +D +++++E L E Q +E L L +A+ I P+ L++ LE Sbjct: 853 EVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEADNIASI--PLEPGKEQQLKEKLE 910 Query: 248 KVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLED----LNTRWKLLQVAVE 303 +VK L E+ PL++ + + + +SP LE+ N +W + A+ Sbjct: 911 QVKLLVEEL-PLRQGILKQLNETGGPVLVSAPISPEEQDKLENKLKQTNLQWIKVSRALP 969 Query: 304 DRVRQLHEAHRDFG 317 ++ ++ +D G Sbjct: 970 EKQGEIEAQIKDLG 983 Score = 40.0 bits (92), Expect = 0.010 Identities = 70/329 (21%), Positives = 138/329 (41%), Gaps = 52/329 (15%) Query: 10 KDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 69 KDL+ + + + DV ++L + K+LR +DD + +N+N W + K+ + Sbjct: 1287 KDLR-QWQTNVDVANDL---ALKLLRDYS-ADDTRKVHMITENINASWRSIHKRVSEREA 1341 Query: 70 HLEASSDQWKRLHLSLQELLVWLQLKD------DELSRQAPIGGDFPAVQKQNDVHRAFK 123 LE + ++ L L++ L WL + + +R+ + D V++ + + Sbjct: 1342 ALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQ 1401 Query: 124 RELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELP------PEERAQNVTRLLRK 177 E++ V + E + L + LEG + R L E R +++ +R Sbjct: 1402 GEIEAHTDVYHNLDENSQKIL--RSLEGSDDAVLLQRRLDNMNFKWSELRKKSLN--IRS 1457 Query: 178 QAEEVNTEWEKLNLHSAD---WQRKIDETLER-------LQELQEATD-----ELDLKLR 222 E + +W++L+L + W + D+ L R +Q+ D + +LK + Sbjct: 1458 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 1517 Query: 223 QAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSP 282 + VI + + V L + + LEK+ E+ P +E +V L R+ Sbjct: 1518 E-PVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPP-EERAQNVTRLLRK---------- 1565 Query: 283 YNLSTLEDLNTRWKLLQVAVEDRVRQLHE 311 E++NT W+ L + D R++ E Sbjct: 1566 ----QAEEVNTEWEKLNLHSADWQRKIDE 1590 Score = 38.5 bits (88), Expect = 0.030 Identities = 111/514 (21%), Positives = 190/514 (36%), Gaps = 59/514 (11%) Query: 2 LHRKTYHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGS-DDAVLLQRRLDNMNFKWSEL 60 L K VK L E+ + L+E +L S S ++ L+ +L N +W ++ Sbjct: 905 LKEKLEQVKLLVEELPLRQGILKQLNETGGPVLVSAPISPEEQDKLENKLKQTNLQWIKV 964 Query: 61 RKKSLNIRSHLEASSDQWKRLHLSLQEL-------LVWLQLKDDELS--RQAPIGGDFP- 110 + + +EA +L L++L L+WL ++L Q G F Sbjct: 965 SRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHLLLWLSPIRNQLEIYNQPNQEGPFDV 1024 Query: 111 -----AVQ-KQNDVHRAFKR--ELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPREL 162 AVQ KQ DV + L ++P + +E + + +L QE R Sbjct: 1025 QETEIAVQAKQPDVEEILSKGQHLYKEKPATQPVKRKLEDLSSEW--KAVNRLLQELRAK 1082 Query: 163 PPE----------ERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQE 212 P+ Q VT L+ + T KL + S+ ++ + + E Sbjct: 1083 QPDLAPGLTTIGASPTQTVT-LVTQPVVTKETAISKLEMPSS-LMLEVPALADFNRAWTE 1140 Query: 213 ATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQ 272 TD L L +VIK VGDL + + + + K KA ++ + + + A+ Sbjct: 1141 LTDWLSLL---DQVIKSQRVMVGDL--EDINEMIIKQKATMQDLEQRRPQLEELITAAQN 1195 Query: 273 LTTLGIQLSPYNLST--LEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQG 330 L + T +E + +W +Q +++R +QL+E +D S +L + Sbjct: 1196 LKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKD----STQWLEAKEEA 1251 Query: 331 PWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKAL 390 + K+ + T K+TE Q DL + + + L Sbjct: 1252 EQVLGQARAKLESW-KEGPYTVDAIQKKITETKQLAKDLRQWQTNV--------DVANDL 1302 Query: 391 CLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCL 450 L LL +A D H + +N I ++ LE+ H L PL ++ L Sbjct: 1303 ALKLLRDYSADDTRKVHMITENINA-SWRSIHKRVSEREAALEETHRLLQQFPLDLEKFL 1361 Query: 451 NWLLNVYDTGR-----TGRIRVLSFKTGIISLCK 479 WL T T + R+L G+ L K Sbjct: 1362 AWLTEAETTANVLQDATRKERLLEDSKGVKELMK 1395 Score = 35.0 bits (79), Expect = 0.33 Identities = 41/178 (23%), Positives = 78/178 (43%), Gaps = 10/178 (5%) Query: 715 LAEMENSNGSYLNDS-ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEE 773 L ++ + G L + ISP E E+ L Q Q + L + + I + ++ Sbjct: 926 LKQLNETGGPVLVSAPISPEEQDKLENKLKQTNLQWIKVSRALPEKQGE----IEAQIKD 981 Query: 774 RGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPT----SPQSPRDAEL 829 G+LE+ L DLEE+ +L ++ Q E P ++ T + P E+ Sbjct: 982 LGQLEKKLEDLEEQLNHLLLWLSPIRNQLEIYNQPNQEGPFDVQETEIAVQAKQPDVEEI 1041 Query: 830 IAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPST 887 +++ + L + K + + LED + + ++ ++RL Q L Q + TT+ + T Sbjct: 1042 LSKGQHLYKEKPATQPVKRKLEDLSSEWKA-VNRLLQELRAKQPDLAPGLTTIGASPT 1098 Score = 32.3 bits (72), Expect = 2.2 Identities = 45/281 (16%), Positives = 104/281 (37%), Gaps = 36/281 (12%) Query: 2 LHRKTYHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVL---------LQRRLDN 52 L K+ + +Q ++ ++Y +L E ++ ++ V L R+ Sbjct: 147 LETKSVEQEVVQSQLNHCVNLYKSLSEVKSEVEMVIKTGRQIVQKKQTENPKELDERVTA 206 Query: 53 MNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAV 112 + ++EL K + LE +++ + L WL D EL++++ + G + Sbjct: 207 LKLHYNELGAKVTERKQQLEKCLKLSRKMRKEMNVLTEWLAATDMELTKRSAVEGMPSNL 266 Query: 113 QKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVT 172 + +A ++E++ ++ + S E T L E L ++ L Sbjct: 267 DSEVAWGKATQKEIEKQKVHLKSITEVGEALKTV--LGKKETLVEDKLSL---------- 314 Query: 173 RLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQ 232 +N+ W + + +W + E + ++ + D + + QA+ + + Sbjct: 315 ---------LNSNWIAVTSRAEEWLNLLLEYQKHMETFDQNVDHITKWIIQADTLLDESE 365 Query: 233 PVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQL 273 Q + +K L+ E+ ++ V D A L Sbjct: 366 K------KKPQQKEDVLKRLKAELNDIRPKVDSTRDQAANL 400 Score = 31.6 bits (70), Expect = 3.7 Identities = 42/234 (17%), Positives = 97/234 (41%), Gaps = 34/234 (14%) Query: 1 MLHRKTYHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSEL 60 +L R + D++ ++++ D NL N G L++ ++ +N +++ + Sbjct: 375 VLKRLKAELNDIRPKVDSTRDQAANLMAN--------RGDHCRKLVEPQISELNHRFAAI 426 Query: 61 R------KKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQK 114 K S+ ++ + +SD K L E+ + LK+++ ++ Sbjct: 427 SHRIKTGKASIPLKELEQFNSDIQKLLEPLEAEIQQGVNLKEEDFNKD------------ 474 Query: 115 QNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRL 174 N+ + +EL + + + R + ++ ++L Q + R+Q Sbjct: 475 MNEDNEGTVKELLQRGDNLQQRITDER---KREEIKIKQQLLQTKHNALKDLRSQR---- 527 Query: 175 LRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIK 228 RK+A E++ +W + + D + +D+ ++L L E DE +K E+ K Sbjct: 528 -RKKALEISHQWYQYKRQADDLLKCLDDIEKKLASLPEPRDERKIKEIDRELQK 580 >gi|5032315 dystrophin Dp427p2 isoform [Homo sapiens] Length = 3562 Score = 1907 bits (4939), Expect = 0.0 Identities = 946/947 (99%), Positives = 947/947 (100%) Query: 10 KDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 69 +DLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS Sbjct: 2616 QDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 2675 Query: 70 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 129 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK Sbjct: 2676 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 2735 Query: 130 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL 189 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL Sbjct: 2736 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL 2795 Query: 190 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV 249 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV Sbjct: 2796 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV 2855 Query: 250 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL 309 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL Sbjct: 2856 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL 2915 Query: 310 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 369 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL Sbjct: 2916 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 2975 Query: 370 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 429 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY Sbjct: 2976 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 3035 Query: 430 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL 489 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL Sbjct: 3036 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL 3095 Query: 490 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA 549 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA Sbjct: 3096 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA 3155 Query: 550 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ 609 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ Sbjct: 3156 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ 3215 Query: 610 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ 669 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ Sbjct: 3216 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ 3275 Query: 670 TVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS 729 TVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS Sbjct: 3276 TVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS 3335 Query: 730 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENR 789 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENR Sbjct: 3336 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENR 3395 Query: 790 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI 849 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI Sbjct: 3396 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI 3455 Query: 850 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD 909 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD Sbjct: 3456 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD 3515 Query: 910 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM 956 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM Sbjct: 3516 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM 3562 Score = 67.8 bits (164), Expect = 5e-11 Identities = 53/235 (22%), Positives = 99/235 (42%), Gaps = 33/235 (14%) Query: 87 ELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTE 146 EL WL L D + Q + GD + + +A ++L+ + P Sbjct: 2358 ELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQ-------------- 2403 Query: 147 QPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLER 206 LE+L + L + Q ++ + E + +W+++ H + +++++E L+ Sbjct: 2404 -----LEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKD 2458 Query: 207 LQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHV 266 + EA +E + L QA SW+ G +D++Q + + K L ++ + NV Sbjct: 2459 STQWLEAKEEAEQVLGQARAKLESWKE-GPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 2517 Query: 267 NDLARQLTTLGIQLSPYNLSTL-------EDLNTRWKLLQVAVEDRVRQLHEAHR 314 NDLA +L L Y+ E++N W+ + V +R L E HR Sbjct: 2518 NDLALKL------LRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHR 2566 Score = 60.5 bits (145), Expect = 7e-09 Identities = 79/375 (21%), Positives = 152/375 (40%), Gaps = 34/375 (9%) Query: 7 YHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLN 66 +++K+LQ I V L+ ++I++ DA +LQ +L ++N +W E+ K+ + Sbjct: 2020 WYLKELQDGIGQRQTVVRTLNATGEEIIQQ-SSKTDASILQEKLGSLNLRWQEVCKQLSD 2078 Query: 67 IRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKREL 126 + LE + L E ++WL+ D+ S G + +K V + EL Sbjct: 2079 RKKRLEEQKNILSEFQRDLNEFVLWLEEADNIASIPLEPGKEQQLKEKLEQV-KLLVEEL 2137 Query: 127 KTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEW 186 ++ ++ ET L P+ PEE+ + L + ++ N +W Sbjct: 2138 PLRQGILKQLNETGGPVLVSAPIS-------------PEEQDK-----LENKLKQTNLQW 2179 Query: 187 EKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHL 246 K++ + Q +I+ ++ L +L++ ++L+ +L + + ++ Q+ Sbjct: 2180 IKVSRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHLLLWLSPIRNQLEIYNQPNQEGP 2239 Query: 247 EKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRV 306 V+ + + +V + + L P LEDL++ WK AV + Sbjct: 2240 FDVQETEIAVQAKQPDVEEILSKGQHLYKEKPATQPVK-RKLEDLSSEWK----AVNRLL 2294 Query: 307 RQLHEAHRDFGP------ASQHFLSTSVQGP---WERAISPNKVPYYINHETQTTCWDHP 357 ++L D P AS T V P E AIS ++P + E + Sbjct: 2295 QELRAKQPDLAPGLTTIGASPTQTVTLVTQPVVTKETAISKLEMPSSLMLEVPALADFNR 2354 Query: 358 KMTELYQSLADLNNV 372 TEL L+ L+ V Sbjct: 2355 AWTELTDWLSLLDQV 2369 Score = 56.2 bits (134), Expect = 1e-07 Identities = 62/314 (19%), Positives = 132/314 (42%), Gaps = 33/314 (10%) Query: 8 HVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNI 67 ++KD + D+ H+ + + +E V LQ L ++F+W ++ K + Sbjct: 1917 NIKDSLQQSSGRIDIIHSKKTAALQSATPVE----RVKLQEALSQLDFQWEKVNKMYKDR 1972 Query: 68 RSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELK 127 + + S ++W+R H ++ WL + ++ R+ I +N H +K LK Sbjct: 1973 QGRFDRSVEKWRRFHYDIKIFNQWL-TEAEQFLRKTQI--------PENWEHAKYKWYLK 2023 Query: 128 TKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWE 187 + I VR E++ Q + ++ +L+++ +N W+ Sbjct: 2024 ELQDGIGQRQTVVRTLNATG-----EEIIQ--------QSSKTDASILQEKLGSLNLRWQ 2070 Query: 188 KLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLE 247 ++ +D +++++E L E Q +E L L +A+ I P+ L++ LE Sbjct: 2071 EVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEADNIASI--PLEPGKEQQLKEKLE 2128 Query: 248 KVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLED----LNTRWKLLQVAVE 303 +VK L E+ PL++ + + + +SP LE+ N +W + A+ Sbjct: 2129 QVKLLVEEL-PLRQGILKQLNETGGPVLVSAPISPEEQDKLENKLKQTNLQWIKVSRALP 2187 Query: 304 DRVRQLHEAHRDFG 317 ++ ++ +D G Sbjct: 2188 EKQGEIEAQIKDLG 2201 Score = 53.9 bits (128), Expect = 7e-07 Identities = 64/312 (20%), Positives = 130/312 (41%), Gaps = 26/312 (8%) Query: 1 MLHRKTYHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSEL 60 +L ++ + L +I+ ++++E QKI E + A L+ L +N +W + Sbjct: 960 ILKKQLKQCRLLVSDIQTIQPSLNSVNEGGQKIKNEAE-PEFASRLETELKELNTQWDHM 1018 Query: 61 RKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHR 120 ++ + L+ ++ L L E+ W+ ++E + +QK + + Sbjct: 1019 CQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEEEYLERDFEYKTPDELQKAVEEMK 1078 Query: 121 AFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAE 180 K E + KE + E+V + + P E L +E + +T + Sbjct: 1079 RAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEALKKE---------LETLTTNYQWLCT 1129 Query: 181 EVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLID 240 +N + + L A W E L L++ + +E++ KL+ E I G + + ++L D Sbjct: 1130 RLNGKCKTLEEVWACWH----ELLSYLEKANKWLNEVEFKLKTTENIPGGAEEISEVL-D 1184 Query: 241 SLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQV 300 SL++ + ++N + + LA+ LT G+ N LE N+RW+ L Sbjct: 1185 SLENLMRH----------SEDNPNQIRILAQTLTDGGVMDELIN-EELETFNSRWRELHE 1233 Query: 301 AVEDRVRQLHEA 312 R + L ++ Sbjct: 1234 EAVRRQKLLEQS 1245 Score = 50.4 bits (119), Expect = 8e-06 Identities = 38/164 (23%), Positives = 85/164 (51%), Gaps = 6/164 (3%) Query: 134 MSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHS 193 + L+ ++ L EQ GL L +E+ + ++ ++R + + EE+ W+KL+ Sbjct: 856 LGELQALQSSLQEQQ-SGLYYLSTTVKEMSKKAPSE-ISRKYQSEFEEIEGRWKKLSSQL 913 Query: 194 ADWQRKIDETLERLQELQEATDELDLKLRQAEV-IKGSWQPVGDLLIDSLQDHLEKVKAL 252 + +K++E + +L+++Q L + + +V +K W +GD I L+ L++ + L Sbjct: 914 VEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEWPALGDSEI--LKKQLKQCRLL 971 Query: 253 RGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLST-LEDLNTRW 295 +I ++ +++ VN+ +++ L T L++LNT+W Sbjct: 972 VSDIQTIQPSLNSVNEGGQKIKNEAEPEFASRLETELKELNTQW 1015 Score = 47.4 bits (111), Expect = 7e-05 Identities = 68/315 (21%), Positives = 125/315 (39%), Gaps = 53/315 (16%) Query: 17 EAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS-----HL 71 E H ++H + + Q + +G + + R + + + S RS HL Sbjct: 140 EEHFQLHHQMHYSQQITVSLAQGYERTSSPKPRFKSYAYTQAAYVTTSDPTRSPFPSQHL 199 Query: 72 EASSDQ------------WKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVH 119 EA D+ R +L+E+L WL +D L Q I D V+ Q H Sbjct: 200 EAPEDKSFGSSLMESEVNLDRYQTALEEVLSWLLSAEDTLQAQGEISNDVEVVKDQFHTH 259 Query: 120 RAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQA 179 + +L + + + L+ L G KL ++ EE +++Q Sbjct: 260 EGYMMDLTAHQGRVGNILQ------LGSKLIGTGKLSED------EETE------VQEQM 301 Query: 180 EEVNTEWEKLNLHSADWQRKIDETL-----ERLQELQEATDELDLKLRQAEVIKGSWQPV 234 +N+ WE L + S + Q + L ++L+EL + + + + R+ E +P+ Sbjct: 302 NLLNSRWECLRVASMEKQSNLHRVLMDLQNQKLKELNDWLTKTEERTRKMEE-----EPL 356 Query: 235 GDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLED---- 290 G L D L+ +++ K L+ + L++ VN L + + + + LE+ Sbjct: 357 GPDLED-LKRQVQQHKVLQED---LEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKV 412 Query: 291 LNTRWKLLQVAVEDR 305 L RW + EDR Sbjct: 413 LGDRWANICRWTEDR 427 Score = 42.4 bits (98), Expect = 0.002 Identities = 53/268 (19%), Positives = 109/268 (40%), Gaps = 26/268 (9%) Query: 47 QRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIG 106 Q + + +W +L + + LE ++ +++ +Q L W+ D L + P Sbjct: 896 QSEFEEIEGRWKKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEWPAL 955 Query: 107 GDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEE 166 GD ++KQ R +++T +P + S EG +K+ E PE Sbjct: 956 GDSEILKKQLKQCRLLVSDIQTIQPSLNSV------------NEGGQKI---KNEAEPEF 1000 Query: 167 RAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQA-- 224 ++ L + +E+NT+W+ + + + LE+ LQ+ E+ + QA Sbjct: 1001 ASR-----LETELKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEE 1055 Query: 225 EVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYN 284 E ++ ++ D LQ +E++K + E + V + + + ++ Sbjct: 1056 EYLERDFEYKTP---DELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEA 1112 Query: 285 L-STLEDLNTRWKLLQVAVEDRVRQLHE 311 L LE L T ++ L + + + L E Sbjct: 1113 LKKELETLTTNYQWLCTRLNGKCKTLEE 1140 Score = 40.0 bits (92), Expect = 0.010 Identities = 70/329 (21%), Positives = 138/329 (41%), Gaps = 52/329 (15%) Query: 10 KDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 69 KDL+ + + + DV ++L + K+LR +DD + +N+N W + K+ + Sbjct: 2505 KDLR-QWQTNVDVANDL---ALKLLRDYS-ADDTRKVHMITENINASWRSIHKRVSEREA 2559 Query: 70 HLEASSDQWKRLHLSLQELLVWLQLKD------DELSRQAPIGGDFPAVQKQNDVHRAFK 123 LE + ++ L L++ L WL + + +R+ + D V++ + + Sbjct: 2560 ALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQ 2619 Query: 124 RELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELP------PEERAQNVTRLLRK 177 E++ V + E + L + LEG + R L E R +++ +R Sbjct: 2620 GEIEAHTDVYHNLDENSQKIL--RSLEGSDDAVLLQRRLDNMNFKWSELRKKSLN--IRS 2675 Query: 178 QAEEVNTEWEKLNLHSAD---WQRKIDETLER-------LQELQEATD-----ELDLKLR 222 E + +W++L+L + W + D+ L R +Q+ D + +LK + Sbjct: 2676 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 2735 Query: 223 QAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSP 282 + VI + + V L + + LEK+ E+ P +E +V L R+ Sbjct: 2736 E-PVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPP-EERAQNVTRLLRK---------- 2783 Query: 283 YNLSTLEDLNTRWKLLQVAVEDRVRQLHE 311 E++NT W+ L + D R++ E Sbjct: 2784 ----QAEEVNTEWEKLNLHSADWQRKIDE 2808 Score = 38.5 bits (88), Expect = 0.030 Identities = 111/514 (21%), Positives = 190/514 (36%), Gaps = 59/514 (11%) Query: 2 LHRKTYHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGS-DDAVLLQRRLDNMNFKWSEL 60 L K VK L E+ + L+E +L S S ++ L+ +L N +W ++ Sbjct: 2123 LKEKLEQVKLLVEELPLRQGILKQLNETGGPVLVSAPISPEEQDKLENKLKQTNLQWIKV 2182 Query: 61 RKKSLNIRSHLEASSDQWKRLHLSLQEL-------LVWLQLKDDELS--RQAPIGGDFP- 110 + + +EA +L L++L L+WL ++L Q G F Sbjct: 2183 SRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHLLLWLSPIRNQLEIYNQPNQEGPFDV 2242 Query: 111 -----AVQ-KQNDVHRAFKR--ELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPREL 162 AVQ KQ DV + L ++P + +E + + +L QE R Sbjct: 2243 QETEIAVQAKQPDVEEILSKGQHLYKEKPATQPVKRKLEDLSSEW--KAVNRLLQELRAK 2300 Query: 163 PPE----------ERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQE 212 P+ Q VT L+ + T KL + S+ ++ + + E Sbjct: 2301 QPDLAPGLTTIGASPTQTVT-LVTQPVVTKETAISKLEMPSS-LMLEVPALADFNRAWTE 2358 Query: 213 ATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQ 272 TD L L +VIK VGDL + + + + K KA ++ + + + A+ Sbjct: 2359 LTDWLSLL---DQVIKSQRVMVGDL--EDINEMIIKQKATMQDLEQRRPQLEELITAAQN 2413 Query: 273 LTTLGIQLSPYNLST--LEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQG 330 L + T +E + +W +Q +++R +QL+E +D S +L + Sbjct: 2414 LKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKD----STQWLEAKEEA 2469 Query: 331 PWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKAL 390 + K+ + T K+TE Q DL + + + L Sbjct: 2470 EQVLGQARAKLESW-KEGPYTVDAIQKKITETKQLAKDLRQWQTNV--------DVANDL 2520 Query: 391 CLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCL 450 L LL +A D H + +N I ++ LE+ H L PL ++ L Sbjct: 2521 ALKLLRDYSADDTRKVHMITENINA-SWRSIHKRVSEREAALEETHRLLQQFPLDLEKFL 2579 Query: 451 NWLLNVYDTGR-----TGRIRVLSFKTGIISLCK 479 WL T T + R+L G+ L K Sbjct: 2580 AWLTEAETTANVLQDATRKERLLEDSKGVKELMK 2613 Score = 35.0 bits (79), Expect = 0.33 Identities = 41/178 (23%), Positives = 78/178 (43%), Gaps = 10/178 (5%) Query: 715 LAEMENSNGSYLNDS-ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEE 773 L ++ + G L + ISP E E+ L Q Q + L + + I + ++ Sbjct: 2144 LKQLNETGGPVLVSAPISPEEQDKLENKLKQTNLQWIKVSRALPEKQGE----IEAQIKD 2199 Query: 774 RGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPT----SPQSPRDAEL 829 G+LE+ L DLEE+ +L ++ Q E P ++ T + P E+ Sbjct: 2200 LGQLEKKLEDLEEQLNHLLLWLSPIRNQLEIYNQPNQEGPFDVQETEIAVQAKQPDVEEI 2259 Query: 830 IAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPST 887 +++ + L + K + + LED + + ++ ++RL Q L Q + TT+ + T Sbjct: 2260 LSKGQHLYKEKPATQPVKRKLEDLSSEWKA-VNRLLQELRAKQPDLAPGLTTIGASPT 2316 Score = 32.3 bits (72), Expect = 2.2 Identities = 45/281 (16%), Positives = 104/281 (37%), Gaps = 36/281 (12%) Query: 2 LHRKTYHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVL---------LQRRLDN 52 L K+ + +Q ++ ++Y +L E ++ ++ V L R+ Sbjct: 1365 LETKSVEQEVVQSQLNHCVNLYKSLSEVKSEVEMVIKTGRQIVQKKQTENPKELDERVTA 1424 Query: 53 MNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAV 112 + ++EL K + LE +++ + L WL D EL++++ + G + Sbjct: 1425 LKLHYNELGAKVTERKQQLEKCLKLSRKMRKEMNVLTEWLAATDMELTKRSAVEGMPSNL 1484 Query: 113 QKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVT 172 + +A ++E++ ++ + S E T L E L ++ L Sbjct: 1485 DSEVAWGKATQKEIEKQKVHLKSITEVGEALKTV--LGKKETLVEDKLSL---------- 1532 Query: 173 RLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQ 232 +N+ W + + +W + E + ++ + D + + QA+ + + Sbjct: 1533 ---------LNSNWIAVTSRAEEWLNLLLEYQKHMETFDQNVDHITKWIIQADTLLDESE 1583 Query: 233 PVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQL 273 Q + +K L+ E+ ++ V D A L Sbjct: 1584 K------KKPQQKEDVLKRLKAELNDIRPKVDSTRDQAANL 1618 Score = 31.6 bits (70), Expect = 3.7 Identities = 42/234 (17%), Positives = 97/234 (41%), Gaps = 34/234 (14%) Query: 1 MLHRKTYHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSEL 60 +L R + D++ ++++ D NL N G L++ ++ +N +++ + Sbjct: 1593 VLKRLKAELNDIRPKVDSTRDQAANLMAN--------RGDHCRKLVEPQISELNHRFAAI 1644 Query: 61 R------KKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQK 114 K S+ ++ + +SD K L E+ + LK+++ ++ Sbjct: 1645 SHRIKTGKASIPLKELEQFNSDIQKLLEPLEAEIQQGVNLKEEDFNKD------------ 1692 Query: 115 QNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRL 174 N+ + +EL + + + R + ++ ++L Q + R+Q Sbjct: 1693 MNEDNEGTVKELLQRGDNLQQRITDER---KREEIKIKQQLLQTKHNALKDLRSQR---- 1745 Query: 175 LRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIK 228 RK+A E++ +W + + D + +D+ ++L L E DE +K E+ K Sbjct: 1746 -RKKALEISHQWYQYKRQADDLLKCLDDIEKKLASLPEPRDERKIKEIDRELQK 1798 >gi|5032287 dystrophin Dp427p1 isoform [Homo sapiens] Length = 3681 Score = 1907 bits (4939), Expect = 0.0 Identities = 946/947 (99%), Positives = 947/947 (100%) Query: 10 KDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 69 +DLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS Sbjct: 2735 QDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 2794 Query: 70 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 129 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK Sbjct: 2795 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 2854 Query: 130 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL 189 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL Sbjct: 2855 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL 2914 Query: 190 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV 249 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV Sbjct: 2915 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV 2974 Query: 250 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL 309 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL Sbjct: 2975 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL 3034 Query: 310 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 369 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL Sbjct: 3035 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 3094 Query: 370 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 429 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY Sbjct: 3095 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 3154 Query: 430 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL 489 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL Sbjct: 3155 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL 3214 Query: 490 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA 549 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA Sbjct: 3215 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA 3274 Query: 550 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ 609 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ Sbjct: 3275 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ 3334 Query: 610 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ 669 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ Sbjct: 3335 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ 3394 Query: 670 TVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS 729 TVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS Sbjct: 3395 TVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS 3454 Query: 730 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENR 789 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENR Sbjct: 3455 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENR 3514 Query: 790 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI 849 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI Sbjct: 3515 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI 3574 Query: 850 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD 909 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD Sbjct: 3575 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD 3634 Query: 910 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM 956 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM Sbjct: 3635 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM 3681 Score = 67.8 bits (164), Expect = 5e-11 Identities = 53/235 (22%), Positives = 99/235 (42%), Gaps = 33/235 (14%) Query: 87 ELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTE 146 EL WL L D + Q + GD + + +A ++L+ + P Sbjct: 2477 ELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQ-------------- 2522 Query: 147 QPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLER 206 LE+L + L + Q ++ + E + +W+++ H + +++++E L+ Sbjct: 2523 -----LEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKD 2577 Query: 207 LQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHV 266 + EA +E + L QA SW+ G +D++Q + + K L ++ + NV Sbjct: 2578 STQWLEAKEEAEQVLGQARAKLESWKE-GPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 2636 Query: 267 NDLARQLTTLGIQLSPYNLSTL-------EDLNTRWKLLQVAVEDRVRQLHEAHR 314 NDLA +L L Y+ E++N W+ + V +R L E HR Sbjct: 2637 NDLALKL------LRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHR 2685 Score = 60.5 bits (145), Expect = 7e-09 Identities = 79/375 (21%), Positives = 152/375 (40%), Gaps = 34/375 (9%) Query: 7 YHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLN 66 +++K+LQ I V L+ ++I++ DA +LQ +L ++N +W E+ K+ + Sbjct: 2139 WYLKELQDGIGQRQTVVRTLNATGEEIIQQ-SSKTDASILQEKLGSLNLRWQEVCKQLSD 2197 Query: 67 IRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKREL 126 + LE + L E ++WL+ D+ S G + +K V + EL Sbjct: 2198 RKKRLEEQKNILSEFQRDLNEFVLWLEEADNIASIPLEPGKEQQLKEKLEQV-KLLVEEL 2256 Query: 127 KTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEW 186 ++ ++ ET L P+ PEE+ + L + ++ N +W Sbjct: 2257 PLRQGILKQLNETGGPVLVSAPIS-------------PEEQDK-----LENKLKQTNLQW 2298 Query: 187 EKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHL 246 K++ + Q +I+ ++ L +L++ ++L+ +L + + ++ Q+ Sbjct: 2299 IKVSRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHLLLWLSPIRNQLEIYNQPNQEGP 2358 Query: 247 EKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRV 306 V+ + + +V + + L P LEDL++ WK AV + Sbjct: 2359 FDVQETEIAVQAKQPDVEEILSKGQHLYKEKPATQPVK-RKLEDLSSEWK----AVNRLL 2413 Query: 307 RQLHEAHRDFGP------ASQHFLSTSVQGP---WERAISPNKVPYYINHETQTTCWDHP 357 ++L D P AS T V P E AIS ++P + E + Sbjct: 2414 QELRAKQPDLAPGLTTIGASPTQTVTLVTQPVVTKETAISKLEMPSSLMLEVPALADFNR 2473 Query: 358 KMTELYQSLADLNNV 372 TEL L+ L+ V Sbjct: 2474 AWTELTDWLSLLDQV 2488 Score = 56.2 bits (134), Expect = 1e-07 Identities = 62/314 (19%), Positives = 132/314 (42%), Gaps = 33/314 (10%) Query: 8 HVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNI 67 ++KD + D+ H+ + + +E V LQ L ++F+W ++ K + Sbjct: 2036 NIKDSLQQSSGRIDIIHSKKTAALQSATPVE----RVKLQEALSQLDFQWEKVNKMYKDR 2091 Query: 68 RSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELK 127 + + S ++W+R H ++ WL + ++ R+ I +N H +K LK Sbjct: 2092 QGRFDRSVEKWRRFHYDIKIFNQWL-TEAEQFLRKTQI--------PENWEHAKYKWYLK 2142 Query: 128 TKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWE 187 + I VR E++ Q + ++ +L+++ +N W+ Sbjct: 2143 ELQDGIGQRQTVVRTLNATG-----EEIIQ--------QSSKTDASILQEKLGSLNLRWQ 2189 Query: 188 KLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLE 247 ++ +D +++++E L E Q +E L L +A+ I P+ L++ LE Sbjct: 2190 EVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEADNIASI--PLEPGKEQQLKEKLE 2247 Query: 248 KVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLED----LNTRWKLLQVAVE 303 +VK L E+ PL++ + + + +SP LE+ N +W + A+ Sbjct: 2248 QVKLLVEEL-PLRQGILKQLNETGGPVLVSAPISPEEQDKLENKLKQTNLQWIKVSRALP 2306 Query: 304 DRVRQLHEAHRDFG 317 ++ ++ +D G Sbjct: 2307 EKQGEIEAQIKDLG 2320 Score = 53.9 bits (128), Expect = 7e-07 Identities = 64/312 (20%), Positives = 130/312 (41%), Gaps = 26/312 (8%) Query: 1 MLHRKTYHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSEL 60 +L ++ + L +I+ ++++E QKI E + A L+ L +N +W + Sbjct: 1079 ILKKQLKQCRLLVSDIQTIQPSLNSVNEGGQKIKNEAE-PEFASRLETELKELNTQWDHM 1137 Query: 61 RKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHR 120 ++ + L+ ++ L L E+ W+ ++E + +QK + + Sbjct: 1138 CQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEEEYLERDFEYKTPDELQKAVEEMK 1197 Query: 121 AFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAE 180 K E + KE + E+V + + P E L +E + +T + Sbjct: 1198 RAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEALKKE---------LETLTTNYQWLCT 1248 Query: 181 EVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLID 240 +N + + L A W E L L++ + +E++ KL+ E I G + + ++L D Sbjct: 1249 RLNGKCKTLEEVWACWH----ELLSYLEKANKWLNEVEFKLKTTENIPGGAEEISEVL-D 1303 Query: 241 SLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQV 300 SL++ + ++N + + LA+ LT G+ N LE N+RW+ L Sbjct: 1304 SLENLMRH----------SEDNPNQIRILAQTLTDGGVMDELIN-EELETFNSRWRELHE 1352 Query: 301 AVEDRVRQLHEA 312 R + L ++ Sbjct: 1353 EAVRRQKLLEQS 1364 Score = 50.4 bits (119), Expect = 8e-06 Identities = 38/164 (23%), Positives = 85/164 (51%), Gaps = 6/164 (3%) Query: 134 MSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHS 193 + L+ ++ L EQ GL L +E+ + ++ ++R + + EE+ W+KL+ Sbjct: 975 LGELQALQSSLQEQQ-SGLYYLSTTVKEMSKKAPSE-ISRKYQSEFEEIEGRWKKLSSQL 1032 Query: 194 ADWQRKIDETLERLQELQEATDELDLKLRQAEV-IKGSWQPVGDLLIDSLQDHLEKVKAL 252 + +K++E + +L+++Q L + + +V +K W +GD I L+ L++ + L Sbjct: 1033 VEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEWPALGDSEI--LKKQLKQCRLL 1090 Query: 253 RGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLST-LEDLNTRW 295 +I ++ +++ VN+ +++ L T L++LNT+W Sbjct: 1091 VSDIQTIQPSLNSVNEGGQKIKNEAEPEFASRLETELKELNTQW 1134 Score = 47.4 bits (111), Expect = 7e-05 Identities = 68/315 (21%), Positives = 125/315 (39%), Gaps = 53/315 (16%) Query: 17 EAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS-----HL 71 E H ++H + + Q + +G + + R + + + S RS HL Sbjct: 259 EEHFQLHHQMHYSQQITVSLAQGYERTSSPKPRFKSYAYTQAAYVTTSDPTRSPFPSQHL 318 Query: 72 EASSDQ------------WKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVH 119 EA D+ R +L+E+L WL +D L Q I D V+ Q H Sbjct: 319 EAPEDKSFGSSLMESEVNLDRYQTALEEVLSWLLSAEDTLQAQGEISNDVEVVKDQFHTH 378 Query: 120 RAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQA 179 + +L + + + L+ L G KL ++ EE +++Q Sbjct: 379 EGYMMDLTAHQGRVGNILQ------LGSKLIGTGKLSED------EETE------VQEQM 420 Query: 180 EEVNTEWEKLNLHSADWQRKIDETL-----ERLQELQEATDELDLKLRQAEVIKGSWQPV 234 +N+ WE L + S + Q + L ++L+EL + + + + R+ E +P+ Sbjct: 421 NLLNSRWECLRVASMEKQSNLHRVLMDLQNQKLKELNDWLTKTEERTRKMEE-----EPL 475 Query: 235 GDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLED---- 290 G L D L+ +++ K L+ + L++ VN L + + + + LE+ Sbjct: 476 GPDLED-LKRQVQQHKVLQED---LEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKV 531 Query: 291 LNTRWKLLQVAVEDR 305 L RW + EDR Sbjct: 532 LGDRWANICRWTEDR 546 Score = 42.4 bits (98), Expect = 0.002 Identities = 53/268 (19%), Positives = 109/268 (40%), Gaps = 26/268 (9%) Query: 47 QRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIG 106 Q + + +W +L + + LE ++ +++ +Q L W+ D L + P Sbjct: 1015 QSEFEEIEGRWKKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEWPAL 1074 Query: 107 GDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEE 166 GD ++KQ R +++T +P + S EG +K+ E PE Sbjct: 1075 GDSEILKKQLKQCRLLVSDIQTIQPSLNSV------------NEGGQKI---KNEAEPEF 1119 Query: 167 RAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQA-- 224 ++ L + +E+NT+W+ + + + LE+ LQ+ E+ + QA Sbjct: 1120 ASR-----LETELKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEE 1174 Query: 225 EVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYN 284 E ++ ++ D LQ +E++K + E + V + + + ++ Sbjct: 1175 EYLERDFEYKTP---DELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEA 1231 Query: 285 L-STLEDLNTRWKLLQVAVEDRVRQLHE 311 L LE L T ++ L + + + L E Sbjct: 1232 LKKELETLTTNYQWLCTRLNGKCKTLEE 1259 Score = 40.0 bits (92), Expect = 0.010 Identities = 70/329 (21%), Positives = 138/329 (41%), Gaps = 52/329 (15%) Query: 10 KDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 69 KDL+ + + + DV ++L + K+LR +DD + +N+N W + K+ + Sbjct: 2624 KDLR-QWQTNVDVANDL---ALKLLRDYS-ADDTRKVHMITENINASWRSIHKRVSEREA 2678 Query: 70 HLEASSDQWKRLHLSLQELLVWLQLKD------DELSRQAPIGGDFPAVQKQNDVHRAFK 123 LE + ++ L L++ L WL + + +R+ + D V++ + + Sbjct: 2679 ALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQ 2738 Query: 124 RELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELP------PEERAQNVTRLLRK 177 E++ V + E + L + LEG + R L E R +++ +R Sbjct: 2739 GEIEAHTDVYHNLDENSQKIL--RSLEGSDDAVLLQRRLDNMNFKWSELRKKSLN--IRS 2794 Query: 178 QAEEVNTEWEKLNLHSAD---WQRKIDETLER-------LQELQEATD-----ELDLKLR 222 E + +W++L+L + W + D+ L R +Q+ D + +LK + Sbjct: 2795 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 2854 Query: 223 QAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSP 282 + VI + + V L + + LEK+ E+ P +E +V L R+ Sbjct: 2855 E-PVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPP-EERAQNVTRLLRK---------- 2902 Query: 283 YNLSTLEDLNTRWKLLQVAVEDRVRQLHE 311 E++NT W+ L + D R++ E Sbjct: 2903 ----QAEEVNTEWEKLNLHSADWQRKIDE 2927 Score = 38.5 bits (88), Expect = 0.030 Identities = 111/514 (21%), Positives = 190/514 (36%), Gaps = 59/514 (11%) Query: 2 LHRKTYHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGS-DDAVLLQRRLDNMNFKWSEL 60 L K VK L E+ + L+E +L S S ++ L+ +L N +W ++ Sbjct: 2242 LKEKLEQVKLLVEELPLRQGILKQLNETGGPVLVSAPISPEEQDKLENKLKQTNLQWIKV 2301 Query: 61 RKKSLNIRSHLEASSDQWKRLHLSLQEL-------LVWLQLKDDELS--RQAPIGGDFP- 110 + + +EA +L L++L L+WL ++L Q G F Sbjct: 2302 SRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHLLLWLSPIRNQLEIYNQPNQEGPFDV 2361 Query: 111 -----AVQ-KQNDVHRAFKR--ELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPREL 162 AVQ KQ DV + L ++P + +E + + +L QE R Sbjct: 2362 QETEIAVQAKQPDVEEILSKGQHLYKEKPATQPVKRKLEDLSSEW--KAVNRLLQELRAK 2419 Query: 163 PPE----------ERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQE 212 P+ Q VT L+ + T KL + S+ ++ + + E Sbjct: 2420 QPDLAPGLTTIGASPTQTVT-LVTQPVVTKETAISKLEMPSS-LMLEVPALADFNRAWTE 2477 Query: 213 ATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQ 272 TD L L +VIK VGDL + + + + K KA ++ + + + A+ Sbjct: 2478 LTDWLSLL---DQVIKSQRVMVGDL--EDINEMIIKQKATMQDLEQRRPQLEELITAAQN 2532 Query: 273 LTTLGIQLSPYNLST--LEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQG 330 L + T +E + +W +Q +++R +QL+E +D S +L + Sbjct: 2533 LKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKD----STQWLEAKEEA 2588 Query: 331 PWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKAL 390 + K+ + T K+TE Q DL + + + L Sbjct: 2589 EQVLGQARAKLESW-KEGPYTVDAIQKKITETKQLAKDLRQWQTNV--------DVANDL 2639 Query: 391 CLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCL 450 L LL +A D H + +N I ++ LE+ H L PL ++ L Sbjct: 2640 ALKLLRDYSADDTRKVHMITENINA-SWRSIHKRVSEREAALEETHRLLQQFPLDLEKFL 2698 Query: 451 NWLLNVYDTGR-----TGRIRVLSFKTGIISLCK 479 WL T T + R+L G+ L K Sbjct: 2699 AWLTEAETTANVLQDATRKERLLEDSKGVKELMK 2732 Score = 35.0 bits (79), Expect = 0.33 Identities = 41/178 (23%), Positives = 78/178 (43%), Gaps = 10/178 (5%) Query: 715 LAEMENSNGSYLNDS-ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEE 773 L ++ + G L + ISP E E+ L Q Q + L + + I + ++ Sbjct: 2263 LKQLNETGGPVLVSAPISPEEQDKLENKLKQTNLQWIKVSRALPEKQGE----IEAQIKD 2318 Query: 774 RGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPT----SPQSPRDAEL 829 G+LE+ L DLEE+ +L ++ Q E P ++ T + P E+ Sbjct: 2319 LGQLEKKLEDLEEQLNHLLLWLSPIRNQLEIYNQPNQEGPFDVQETEIAVQAKQPDVEEI 2378 Query: 830 IAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPST 887 +++ + L + K + + LED + + ++ ++RL Q L Q + TT+ + T Sbjct: 2379 LSKGQHLYKEKPATQPVKRKLEDLSSEWKA-VNRLLQELRAKQPDLAPGLTTIGASPT 2435 Score = 32.3 bits (72), Expect = 2.2 Identities = 45/281 (16%), Positives = 104/281 (37%), Gaps = 36/281 (12%) Query: 2 LHRKTYHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVL---------LQRRLDN 52 L K+ + +Q ++ ++Y +L E ++ ++ V L R+ Sbjct: 1484 LETKSVEQEVVQSQLNHCVNLYKSLSEVKSEVEMVIKTGRQIVQKKQTENPKELDERVTA 1543 Query: 53 MNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAV 112 + ++EL K + LE +++ + L WL D EL++++ + G + Sbjct: 1544 LKLHYNELGAKVTERKQQLEKCLKLSRKMRKEMNVLTEWLAATDMELTKRSAVEGMPSNL 1603 Query: 113 QKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVT 172 + +A ++E++ ++ + S E T L E L ++ L Sbjct: 1604 DSEVAWGKATQKEIEKQKVHLKSITEVGEALKTV--LGKKETLVEDKLSL---------- 1651 Query: 173 RLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQ 232 +N+ W + + +W + E + ++ + D + + QA+ + + Sbjct: 1652 ---------LNSNWIAVTSRAEEWLNLLLEYQKHMETFDQNVDHITKWIIQADTLLDESE 1702 Query: 233 PVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQL 273 Q + +K L+ E+ ++ V D A L Sbjct: 1703 K------KKPQQKEDVLKRLKAELNDIRPKVDSTRDQAANL 1737 Score = 31.6 bits (70), Expect = 3.7 Identities = 42/234 (17%), Positives = 97/234 (41%), Gaps = 34/234 (14%) Query: 1 MLHRKTYHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSEL 60 +L R + D++ ++++ D NL N G L++ ++ +N +++ + Sbjct: 1712 VLKRLKAELNDIRPKVDSTRDQAANLMAN--------RGDHCRKLVEPQISELNHRFAAI 1763 Query: 61 R------KKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQK 114 K S+ ++ + +SD K L E+ + LK+++ ++ Sbjct: 1764 SHRIKTGKASIPLKELEQFNSDIQKLLEPLEAEIQQGVNLKEEDFNKD------------ 1811 Query: 115 QNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRL 174 N+ + +EL + + + R + ++ ++L Q + R+Q Sbjct: 1812 MNEDNEGTVKELLQRGDNLQQRITDER---KREEIKIKQQLLQTKHNALKDLRSQR---- 1864 Query: 175 LRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIK 228 RK+A E++ +W + + D + +D+ ++L L E DE +K E+ K Sbjct: 1865 -RKKALEISHQWYQYKRQADDLLKCLDDIEKKLASLPEPRDERKIKEIDRELQK 1917 >gi|5032293 dystrophin Dp140 isoform [Homo sapiens] Length = 1225 Score = 1907 bits (4939), Expect = 0.0 Identities = 946/947 (99%), Positives = 947/947 (100%) Query: 10 KDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 69 +DLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS Sbjct: 279 QDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 338 Query: 70 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 129 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK Sbjct: 339 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 398 Query: 130 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL 189 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL Sbjct: 399 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL 458 Query: 190 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV 249 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV Sbjct: 459 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV 518 Query: 250 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL 309 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL Sbjct: 519 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL 578 Query: 310 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 369 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL Sbjct: 579 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 638 Query: 370 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 429 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY Sbjct: 639 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 698 Query: 430 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL 489 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL Sbjct: 699 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL 758 Query: 490 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA 549 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA Sbjct: 759 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA 818 Query: 550 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ 609 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ Sbjct: 819 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ 878 Query: 610 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ 669 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ Sbjct: 879 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ 938 Query: 670 TVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS 729 TVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS Sbjct: 939 TVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS 998 Query: 730 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENR 789 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENR Sbjct: 999 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENR 1058 Query: 790 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI 849 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI Sbjct: 1059 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI 1118 Query: 850 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD 909 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD Sbjct: 1119 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD 1178 Query: 910 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM 956 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM Sbjct: 1179 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM 1225 Score = 67.8 bits (164), Expect = 5e-11 Identities = 53/235 (22%), Positives = 99/235 (42%), Gaps = 33/235 (14%) Query: 87 ELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTE 146 EL WL L D + Q + GD + + +A ++L+ + P Sbjct: 21 ELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQ-------------- 66 Query: 147 QPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLER 206 LE+L + L + Q ++ + E + +W+++ H + +++++E L+ Sbjct: 67 -----LEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKD 121 Query: 207 LQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHV 266 + EA +E + L QA SW+ G +D++Q + + K L ++ + NV Sbjct: 122 STQWLEAKEEAEQVLGQARAKLESWKE-GPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180 Query: 267 NDLARQLTTLGIQLSPYNLSTL-------EDLNTRWKLLQVAVEDRVRQLHEAHR 314 NDLA +L L Y+ E++N W+ + V +R L E HR Sbjct: 181 NDLALKL------LRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHR 229 Score = 40.0 bits (92), Expect = 0.010 Identities = 70/329 (21%), Positives = 138/329 (41%), Gaps = 52/329 (15%) Query: 10 KDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 69 KDL+ + + + DV ++L + K+LR +DD + +N+N W + K+ + Sbjct: 168 KDLR-QWQTNVDVANDL---ALKLLRDYS-ADDTRKVHMITENINASWRSIHKRVSEREA 222 Query: 70 HLEASSDQWKRLHLSLQELLVWLQLKD------DELSRQAPIGGDFPAVQKQNDVHRAFK 123 LE + ++ L L++ L WL + + +R+ + D V++ + + Sbjct: 223 ALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQ 282 Query: 124 RELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELP------PEERAQNVTRLLRK 177 E++ V + E + L + LEG + R L E R +++ +R Sbjct: 283 GEIEAHTDVYHNLDENSQKIL--RSLEGSDDAVLLQRRLDNMNFKWSELRKKSLN--IRS 338 Query: 178 QAEEVNTEWEKLNLHSAD---WQRKIDETLER-------LQELQEATD-----ELDLKLR 222 E + +W++L+L + W + D+ L R +Q+ D + +LK + Sbjct: 339 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 398 Query: 223 QAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSP 282 + VI + + V L + + LEK+ E+ P +E +V L R+ Sbjct: 399 E-PVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPP-EERAQNVTRLLRK---------- 446 Query: 283 YNLSTLEDLNTRWKLLQVAVEDRVRQLHE 311 E++NT W+ L + D R++ E Sbjct: 447 ----QAEEVNTEWEKLNLHSADWQRKIDE 471 >gi|5032285 dystrophin Dp427l isoform [Homo sapiens] Length = 3562 Score = 1907 bits (4939), Expect = 0.0 Identities = 946/947 (99%), Positives = 947/947 (100%) Query: 10 KDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 69 +DLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS Sbjct: 2616 QDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 2675 Query: 70 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 129 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK Sbjct: 2676 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 2735 Query: 130 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL 189 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL Sbjct: 2736 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL 2795 Query: 190 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV 249 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV Sbjct: 2796 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV 2855 Query: 250 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL 309 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL Sbjct: 2856 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL 2915 Query: 310 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 369 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL Sbjct: 2916 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 2975 Query: 370 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 429 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY Sbjct: 2976 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 3035 Query: 430 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL 489 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL Sbjct: 3036 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL 3095 Query: 490 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA 549 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA Sbjct: 3096 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA 3155 Query: 550 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ 609 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ Sbjct: 3156 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ 3215 Query: 610 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ 669 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ Sbjct: 3216 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ 3275 Query: 670 TVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS 729 TVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS Sbjct: 3276 TVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS 3335 Query: 730 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENR 789 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENR Sbjct: 3336 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENR 3395 Query: 790 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI 849 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI Sbjct: 3396 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI 3455 Query: 850 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD 909 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD Sbjct: 3456 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD 3515 Query: 910 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM 956 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM Sbjct: 3516 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM 3562 Score = 67.8 bits (164), Expect = 5e-11 Identities = 53/235 (22%), Positives = 99/235 (42%), Gaps = 33/235 (14%) Query: 87 ELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTE 146 EL WL L D + Q + GD + + +A ++L+ + P Sbjct: 2358 ELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQ-------------- 2403 Query: 147 QPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLER 206 LE+L + L + Q ++ + E + +W+++ H + +++++E L+ Sbjct: 2404 -----LEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKD 2458 Query: 207 LQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHV 266 + EA +E + L QA SW+ G +D++Q + + K L ++ + NV Sbjct: 2459 STQWLEAKEEAEQVLGQARAKLESWKE-GPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 2517 Query: 267 NDLARQLTTLGIQLSPYNLSTL-------EDLNTRWKLLQVAVEDRVRQLHEAHR 314 NDLA +L L Y+ E++N W+ + V +R L E HR Sbjct: 2518 NDLALKL------LRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHR 2566 Score = 60.5 bits (145), Expect = 7e-09 Identities = 79/375 (21%), Positives = 152/375 (40%), Gaps = 34/375 (9%) Query: 7 YHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLN 66 +++K+LQ I V L+ ++I++ DA +LQ +L ++N +W E+ K+ + Sbjct: 2020 WYLKELQDGIGQRQTVVRTLNATGEEIIQQ-SSKTDASILQEKLGSLNLRWQEVCKQLSD 2078 Query: 67 IRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKREL 126 + LE + L E ++WL+ D+ S G + +K V + EL Sbjct: 2079 RKKRLEEQKNILSEFQRDLNEFVLWLEEADNIASIPLEPGKEQQLKEKLEQV-KLLVEEL 2137 Query: 127 KTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEW 186 ++ ++ ET L P+ PEE+ + L + ++ N +W Sbjct: 2138 PLRQGILKQLNETGGPVLVSAPIS-------------PEEQDK-----LENKLKQTNLQW 2179 Query: 187 EKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHL 246 K++ + Q +I+ ++ L +L++ ++L+ +L + + ++ Q+ Sbjct: 2180 IKVSRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHLLLWLSPIRNQLEIYNQPNQEGP 2239 Query: 247 EKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRV 306 V+ + + +V + + L P LEDL++ WK AV + Sbjct: 2240 FDVQETEIAVQAKQPDVEEILSKGQHLYKEKPATQPVK-RKLEDLSSEWK----AVNRLL 2294 Query: 307 RQLHEAHRDFGP------ASQHFLSTSVQGP---WERAISPNKVPYYINHETQTTCWDHP 357 ++L D P AS T V P E AIS ++P + E + Sbjct: 2295 QELRAKQPDLAPGLTTIGASPTQTVTLVTQPVVTKETAISKLEMPSSLMLEVPALADFNR 2354 Query: 358 KMTELYQSLADLNNV 372 TEL L+ L+ V Sbjct: 2355 AWTELTDWLSLLDQV 2369 Score = 56.2 bits (134), Expect = 1e-07 Identities = 62/314 (19%), Positives = 132/314 (42%), Gaps = 33/314 (10%) Query: 8 HVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNI 67 ++KD + D+ H+ + + +E V LQ L ++F+W ++ K + Sbjct: 1917 NIKDSLQQSSGRIDIIHSKKTAALQSATPVE----RVKLQEALSQLDFQWEKVNKMYKDR 1972 Query: 68 RSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELK 127 + + S ++W+R H ++ WL + ++ R+ I +N H +K LK Sbjct: 1973 QGRFDRSVEKWRRFHYDIKIFNQWL-TEAEQFLRKTQI--------PENWEHAKYKWYLK 2023 Query: 128 TKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWE 187 + I VR E++ Q + ++ +L+++ +N W+ Sbjct: 2024 ELQDGIGQRQTVVRTLNATG-----EEIIQ--------QSSKTDASILQEKLGSLNLRWQ 2070 Query: 188 KLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLE 247 ++ +D +++++E L E Q +E L L +A+ I P+ L++ LE Sbjct: 2071 EVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEADNIASI--PLEPGKEQQLKEKLE 2128 Query: 248 KVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLED----LNTRWKLLQVAVE 303 +VK L E+ PL++ + + + +SP LE+ N +W + A+ Sbjct: 2129 QVKLLVEEL-PLRQGILKQLNETGGPVLVSAPISPEEQDKLENKLKQTNLQWIKVSRALP 2187 Query: 304 DRVRQLHEAHRDFG 317 ++ ++ +D G Sbjct: 2188 EKQGEIEAQIKDLG 2201 Score = 53.9 bits (128), Expect = 7e-07 Identities = 64/312 (20%), Positives = 130/312 (41%), Gaps = 26/312 (8%) Query: 1 MLHRKTYHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSEL 60 +L ++ + L +I+ ++++E QKI E + A L+ L +N +W + Sbjct: 960 ILKKQLKQCRLLVSDIQTIQPSLNSVNEGGQKIKNEAE-PEFASRLETELKELNTQWDHM 1018 Query: 61 RKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHR 120 ++ + L+ ++ L L E+ W+ ++E + +QK + + Sbjct: 1019 CQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEEEYLERDFEYKTPDELQKAVEEMK 1078 Query: 121 AFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAE 180 K E + KE + E+V + + P E L +E + +T + Sbjct: 1079 RAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEALKKE---------LETLTTNYQWLCT 1129 Query: 181 EVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLID 240 +N + + L A W E L L++ + +E++ KL+ E I G + + ++L D Sbjct: 1130 RLNGKCKTLEEVWACWH----ELLSYLEKANKWLNEVEFKLKTTENIPGGAEEISEVL-D 1184 Query: 241 SLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQV 300 SL++ + ++N + + LA+ LT G+ N LE N+RW+ L Sbjct: 1185 SLENLMRH----------SEDNPNQIRILAQTLTDGGVMDELIN-EELETFNSRWRELHE 1233 Query: 301 AVEDRVRQLHEA 312 R + L ++ Sbjct: 1234 EAVRRQKLLEQS 1245 Score = 50.4 bits (119), Expect = 8e-06 Identities = 38/164 (23%), Positives = 85/164 (51%), Gaps = 6/164 (3%) Query: 134 MSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHS 193 + L+ ++ L EQ GL L +E+ + ++ ++R + + EE+ W+KL+ Sbjct: 856 LGELQALQSSLQEQQ-SGLYYLSTTVKEMSKKAPSE-ISRKYQSEFEEIEGRWKKLSSQL 913 Query: 194 ADWQRKIDETLERLQELQEATDELDLKLRQAEV-IKGSWQPVGDLLIDSLQDHLEKVKAL 252 + +K++E + +L+++Q L + + +V +K W +GD I L+ L++ + L Sbjct: 914 VEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEWPALGDSEI--LKKQLKQCRLL 971 Query: 253 RGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLST-LEDLNTRW 295 +I ++ +++ VN+ +++ L T L++LNT+W Sbjct: 972 VSDIQTIQPSLNSVNEGGQKIKNEAEPEFASRLETELKELNTQW 1015 Score = 47.4 bits (111), Expect = 7e-05 Identities = 68/315 (21%), Positives = 125/315 (39%), Gaps = 53/315 (16%) Query: 17 EAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS-----HL 71 E H ++H + + Q + +G + + R + + + S RS HL Sbjct: 140 EEHFQLHHQMHYSQQITVSLAQGYERTSSPKPRFKSYAYTQAAYVTTSDPTRSPFPSQHL 199 Query: 72 EASSDQ------------WKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVH 119 EA D+ R +L+E+L WL +D L Q I D V+ Q H Sbjct: 200 EAPEDKSFGSSLMESEVNLDRYQTALEEVLSWLLSAEDTLQAQGEISNDVEVVKDQFHTH 259 Query: 120 RAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQA 179 + +L + + + L+ L G KL ++ EE +++Q Sbjct: 260 EGYMMDLTAHQGRVGNILQ------LGSKLIGTGKLSED------EETE------VQEQM 301 Query: 180 EEVNTEWEKLNLHSADWQRKIDETL-----ERLQELQEATDELDLKLRQAEVIKGSWQPV 234 +N+ WE L + S + Q + L ++L+EL + + + + R+ E +P+ Sbjct: 302 NLLNSRWECLRVASMEKQSNLHRVLMDLQNQKLKELNDWLTKTEERTRKMEE-----EPL 356 Query: 235 GDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLED---- 290 G L D L+ +++ K L+ + L++ VN L + + + + LE+ Sbjct: 357 GPDLED-LKRQVQQHKVLQED---LEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKV 412 Query: 291 LNTRWKLLQVAVEDR 305 L RW + EDR Sbjct: 413 LGDRWANICRWTEDR 427 Score = 42.4 bits (98), Expect = 0.002 Identities = 53/268 (19%), Positives = 109/268 (40%), Gaps = 26/268 (9%) Query: 47 QRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIG 106 Q + + +W +L + + LE ++ +++ +Q L W+ D L + P Sbjct: 896 QSEFEEIEGRWKKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEWPAL 955 Query: 107 GDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEE 166 GD ++KQ R +++T +P + S EG +K+ E PE Sbjct: 956 GDSEILKKQLKQCRLLVSDIQTIQPSLNSV------------NEGGQKI---KNEAEPEF 1000 Query: 167 RAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQA-- 224 ++ L + +E+NT+W+ + + + LE+ LQ+ E+ + QA Sbjct: 1001 ASR-----LETELKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEE 1055 Query: 225 EVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYN 284 E ++ ++ D LQ +E++K + E + V + + + ++ Sbjct: 1056 EYLERDFEYKTP---DELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEA 1112 Query: 285 L-STLEDLNTRWKLLQVAVEDRVRQLHE 311 L LE L T ++ L + + + L E Sbjct: 1113 LKKELETLTTNYQWLCTRLNGKCKTLEE 1140 Score = 40.0 bits (92), Expect = 0.010 Identities = 70/329 (21%), Positives = 138/329 (41%), Gaps = 52/329 (15%) Query: 10 KDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 69 KDL+ + + + DV ++L + K+LR +DD + +N+N W + K+ + Sbjct: 2505 KDLR-QWQTNVDVANDL---ALKLLRDYS-ADDTRKVHMITENINASWRSIHKRVSEREA 2559 Query: 70 HLEASSDQWKRLHLSLQELLVWLQLKD------DELSRQAPIGGDFPAVQKQNDVHRAFK 123 LE + ++ L L++ L WL + + +R+ + D V++ + + Sbjct: 2560 ALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQ 2619 Query: 124 RELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELP------PEERAQNVTRLLRK 177 E++ V + E + L + LEG + R L E R +++ +R Sbjct: 2620 GEIEAHTDVYHNLDENSQKIL--RSLEGSDDAVLLQRRLDNMNFKWSELRKKSLN--IRS 2675 Query: 178 QAEEVNTEWEKLNLHSAD---WQRKIDETLER-------LQELQEATD-----ELDLKLR 222 E + +W++L+L + W + D+ L R +Q+ D + +LK + Sbjct: 2676 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 2735 Query: 223 QAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSP 282 + VI + + V L + + LEK+ E+ P +E +V L R+ Sbjct: 2736 E-PVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPP-EERAQNVTRLLRK---------- 2783 Query: 283 YNLSTLEDLNTRWKLLQVAVEDRVRQLHE 311 E++NT W+ L + D R++ E Sbjct: 2784 ----QAEEVNTEWEKLNLHSADWQRKIDE 2808 Score = 38.5 bits (88), Expect = 0.030 Identities = 111/514 (21%), Positives = 190/514 (36%), Gaps = 59/514 (11%) Query: 2 LHRKTYHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGS-DDAVLLQRRLDNMNFKWSEL 60 L K VK L E+ + L+E +L S S ++ L+ +L N +W ++ Sbjct: 2123 LKEKLEQVKLLVEELPLRQGILKQLNETGGPVLVSAPISPEEQDKLENKLKQTNLQWIKV 2182 Query: 61 RKKSLNIRSHLEASSDQWKRLHLSLQEL-------LVWLQLKDDELS--RQAPIGGDFP- 110 + + +EA +L L++L L+WL ++L Q G F Sbjct: 2183 SRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHLLLWLSPIRNQLEIYNQPNQEGPFDV 2242 Query: 111 -----AVQ-KQNDVHRAFKR--ELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPREL 162 AVQ KQ DV + L ++P + +E + + +L QE R Sbjct: 2243 QETEIAVQAKQPDVEEILSKGQHLYKEKPATQPVKRKLEDLSSEW--KAVNRLLQELRAK 2300 Query: 163 PPE----------ERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQE 212 P+ Q VT L+ + T KL + S+ ++ + + E Sbjct: 2301 QPDLAPGLTTIGASPTQTVT-LVTQPVVTKETAISKLEMPSS-LMLEVPALADFNRAWTE 2358 Query: 213 ATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQ 272 TD L L +VIK VGDL + + + + K KA ++ + + + A+ Sbjct: 2359 LTDWLSLL---DQVIKSQRVMVGDL--EDINEMIIKQKATMQDLEQRRPQLEELITAAQN 2413 Query: 273 LTTLGIQLSPYNLST--LEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQG 330 L + T +E + +W +Q +++R +QL+E +D S +L + Sbjct: 2414 LKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKD----STQWLEAKEEA 2469 Query: 331 PWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKAL 390 + K+ + T K+TE Q DL + + + L Sbjct: 2470 EQVLGQARAKLESW-KEGPYTVDAIQKKITETKQLAKDLRQWQTNV--------DVANDL 2520 Query: 391 CLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCL 450 L LL +A D H + +N I ++ LE+ H L PL ++ L Sbjct: 2521 ALKLLRDYSADDTRKVHMITENINA-SWRSIHKRVSEREAALEETHRLLQQFPLDLEKFL 2579 Query: 451 NWLLNVYDTGR-----TGRIRVLSFKTGIISLCK 479 WL T T + R+L G+ L K Sbjct: 2580 AWLTEAETTANVLQDATRKERLLEDSKGVKELMK 2613 Score = 35.0 bits (79), Expect = 0.33 Identities = 41/178 (23%), Positives = 78/178 (43%), Gaps = 10/178 (5%) Query: 715 LAEMENSNGSYLNDS-ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEE 773 L ++ + G L + ISP E E+ L Q Q + L + + I + ++ Sbjct: 2144 LKQLNETGGPVLVSAPISPEEQDKLENKLKQTNLQWIKVSRALPEKQGE----IEAQIKD 2199 Query: 774 RGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPT----SPQSPRDAEL 829 G+LE+ L DLEE+ +L ++ Q E P ++ T + P E+ Sbjct: 2200 LGQLEKKLEDLEEQLNHLLLWLSPIRNQLEIYNQPNQEGPFDVQETEIAVQAKQPDVEEI 2259 Query: 830 IAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPST 887 +++ + L + K + + LED + + ++ ++RL Q L Q + TT+ + T Sbjct: 2260 LSKGQHLYKEKPATQPVKRKLEDLSSEWKA-VNRLLQELRAKQPDLAPGLTTIGASPT 2316 Score = 32.3 bits (72), Expect = 2.2 Identities = 45/281 (16%), Positives = 104/281 (37%), Gaps = 36/281 (12%) Query: 2 LHRKTYHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVL---------LQRRLDN 52 L K+ + +Q ++ ++Y +L E ++ ++ V L R+ Sbjct: 1365 LETKSVEQEVVQSQLNHCVNLYKSLSEVKSEVEMVIKTGRQIVQKKQTENPKELDERVTA 1424 Query: 53 MNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAV 112 + ++EL K + LE +++ + L WL D EL++++ + G + Sbjct: 1425 LKLHYNELGAKVTERKQQLEKCLKLSRKMRKEMNVLTEWLAATDMELTKRSAVEGMPSNL 1484 Query: 113 QKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVT 172 + +A ++E++ ++ + S E T L E L ++ L Sbjct: 1485 DSEVAWGKATQKEIEKQKVHLKSITEVGEALKTV--LGKKETLVEDKLSL---------- 1532 Query: 173 RLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQ 232 +N+ W + + +W + E + ++ + D + + QA+ + + Sbjct: 1533 ---------LNSNWIAVTSRAEEWLNLLLEYQKHMETFDQNVDHITKWIIQADTLLDESE 1583 Query: 233 PVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQL 273 Q + +K L+ E+ ++ V D A L Sbjct: 1584 K------KKPQQKEDVLKRLKAELNDIRPKVDSTRDQAANL 1618 Score = 31.6 bits (70), Expect = 3.7 Identities = 42/234 (17%), Positives = 97/234 (41%), Gaps = 34/234 (14%) Query: 1 MLHRKTYHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSEL 60 +L R + D++ ++++ D NL N G L++ ++ +N +++ + Sbjct: 1593 VLKRLKAELNDIRPKVDSTRDQAANLMAN--------RGDHCRKLVEPQISELNHRFAAI 1644 Query: 61 R------KKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQK 114 K S+ ++ + +SD K L E+ + LK+++ ++ Sbjct: 1645 SHRIKTGKASIPLKELEQFNSDIQKLLEPLEAEIQQGVNLKEEDFNKD------------ 1692 Query: 115 QNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRL 174 N+ + +EL + + + R + ++ ++L Q + R+Q Sbjct: 1693 MNEDNEGTVKELLQRGDNLQQRITDER---KREEIKIKQQLLQTKHNALKDLRSQR---- 1745 Query: 175 LRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIK 228 RK+A E++ +W + + D + +D+ ++L L E DE +K E+ K Sbjct: 1746 -RKKALEISHQWYQYKRQADDLLKCLDDIEKKLASLPEPRDERKIKEIDRELQK 1798 >gi|5032283 dystrophin Dp427m isoform [Homo sapiens] Length = 3685 Score = 1907 bits (4939), Expect = 0.0 Identities = 946/947 (99%), Positives = 947/947 (100%) Query: 10 KDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 69 +DLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS Sbjct: 2739 QDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 2798 Query: 70 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 129 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK Sbjct: 2799 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 2858 Query: 130 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL 189 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL Sbjct: 2859 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL 2918 Query: 190 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV 249 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV Sbjct: 2919 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV 2978 Query: 250 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL 309 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL Sbjct: 2979 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL 3038 Query: 310 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 369 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL Sbjct: 3039 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 3098 Query: 370 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 429 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY Sbjct: 3099 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 3158 Query: 430 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL 489 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL Sbjct: 3159 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL 3218 Query: 490 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA 549 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA Sbjct: 3219 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA 3278 Query: 550 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ 609 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ Sbjct: 3279 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ 3338 Query: 610 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ 669 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ Sbjct: 3339 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ 3398 Query: 670 TVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS 729 TVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS Sbjct: 3399 TVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS 3458 Query: 730 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENR 789 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENR Sbjct: 3459 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENR 3518 Query: 790 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI 849 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI Sbjct: 3519 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI 3578 Query: 850 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD 909 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD Sbjct: 3579 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD 3638 Query: 910 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM 956 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM Sbjct: 3639 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM 3685 Score = 67.8 bits (164), Expect = 5e-11 Identities = 53/235 (22%), Positives = 99/235 (42%), Gaps = 33/235 (14%) Query: 87 ELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTE 146 EL WL L D + Q + GD + + +A ++L+ + P Sbjct: 2481 ELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQ-------------- 2526 Query: 147 QPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLER 206 LE+L + L + Q ++ + E + +W+++ H + +++++E L+ Sbjct: 2527 -----LEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKD 2581 Query: 207 LQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHV 266 + EA +E + L QA SW+ G +D++Q + + K L ++ + NV Sbjct: 2582 STQWLEAKEEAEQVLGQARAKLESWKE-GPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 2640 Query: 267 NDLARQLTTLGIQLSPYNLSTL-------EDLNTRWKLLQVAVEDRVRQLHEAHR 314 NDLA +L L Y+ E++N W+ + V +R L E HR Sbjct: 2641 NDLALKL------LRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHR 2689 Score = 60.5 bits (145), Expect = 7e-09 Identities = 79/375 (21%), Positives = 152/375 (40%), Gaps = 34/375 (9%) Query: 7 YHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLN 66 +++K+LQ I V L+ ++I++ DA +LQ +L ++N +W E+ K+ + Sbjct: 2143 WYLKELQDGIGQRQTVVRTLNATGEEIIQQ-SSKTDASILQEKLGSLNLRWQEVCKQLSD 2201 Query: 67 IRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKREL 126 + LE + L E ++WL+ D+ S G + +K V + EL Sbjct: 2202 RKKRLEEQKNILSEFQRDLNEFVLWLEEADNIASIPLEPGKEQQLKEKLEQV-KLLVEEL 2260 Query: 127 KTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEW 186 ++ ++ ET L P+ PEE+ + L + ++ N +W Sbjct: 2261 PLRQGILKQLNETGGPVLVSAPIS-------------PEEQDK-----LENKLKQTNLQW 2302 Query: 187 EKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHL 246 K++ + Q +I+ ++ L +L++ ++L+ +L + + ++ Q+ Sbjct: 2303 IKVSRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHLLLWLSPIRNQLEIYNQPNQEGP 2362 Query: 247 EKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRV 306 V+ + + +V + + L P LEDL++ WK AV + Sbjct: 2363 FDVQETEIAVQAKQPDVEEILSKGQHLYKEKPATQPVK-RKLEDLSSEWK----AVNRLL 2417 Query: 307 RQLHEAHRDFGP------ASQHFLSTSVQGP---WERAISPNKVPYYINHETQTTCWDHP 357 ++L D P AS T V P E AIS ++P + E + Sbjct: 2418 QELRAKQPDLAPGLTTIGASPTQTVTLVTQPVVTKETAISKLEMPSSLMLEVPALADFNR 2477 Query: 358 KMTELYQSLADLNNV 372 TEL L+ L+ V Sbjct: 2478 AWTELTDWLSLLDQV 2492 Score = 56.2 bits (134), Expect = 1e-07 Identities = 62/314 (19%), Positives = 132/314 (42%), Gaps = 33/314 (10%) Query: 8 HVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNI 67 ++KD + D+ H+ + + +E V LQ L ++F+W ++ K + Sbjct: 2040 NIKDSLQQSSGRIDIIHSKKTAALQSATPVE----RVKLQEALSQLDFQWEKVNKMYKDR 2095 Query: 68 RSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELK 127 + + S ++W+R H ++ WL + ++ R+ I +N H +K LK Sbjct: 2096 QGRFDRSVEKWRRFHYDIKIFNQWL-TEAEQFLRKTQI--------PENWEHAKYKWYLK 2146 Query: 128 TKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWE 187 + I VR E++ Q + ++ +L+++ +N W+ Sbjct: 2147 ELQDGIGQRQTVVRTLNATG-----EEIIQ--------QSSKTDASILQEKLGSLNLRWQ 2193 Query: 188 KLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLE 247 ++ +D +++++E L E Q +E L L +A+ I P+ L++ LE Sbjct: 2194 EVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEADNIASI--PLEPGKEQQLKEKLE 2251 Query: 248 KVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLED----LNTRWKLLQVAVE 303 +VK L E+ PL++ + + + +SP LE+ N +W + A+ Sbjct: 2252 QVKLLVEEL-PLRQGILKQLNETGGPVLVSAPISPEEQDKLENKLKQTNLQWIKVSRALP 2310 Query: 304 DRVRQLHEAHRDFG 317 ++ ++ +D G Sbjct: 2311 EKQGEIEAQIKDLG 2324 Score = 53.9 bits (128), Expect = 7e-07 Identities = 64/312 (20%), Positives = 130/312 (41%), Gaps = 26/312 (8%) Query: 1 MLHRKTYHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSEL 60 +L ++ + L +I+ ++++E QKI E + A L+ L +N +W + Sbjct: 1083 ILKKQLKQCRLLVSDIQTIQPSLNSVNEGGQKIKNEAE-PEFASRLETELKELNTQWDHM 1141 Query: 61 RKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHR 120 ++ + L+ ++ L L E+ W+ ++E + +QK + + Sbjct: 1142 CQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEEEYLERDFEYKTPDELQKAVEEMK 1201 Query: 121 AFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAE 180 K E + KE + E+V + + P E L +E + +T + Sbjct: 1202 RAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEALKKE---------LETLTTNYQWLCT 1252 Query: 181 EVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLID 240 +N + + L A W E L L++ + +E++ KL+ E I G + + ++L D Sbjct: 1253 RLNGKCKTLEEVWACWH----ELLSYLEKANKWLNEVEFKLKTTENIPGGAEEISEVL-D 1307 Query: 241 SLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQV 300 SL++ + ++N + + LA+ LT G+ N LE N+RW+ L Sbjct: 1308 SLENLMRH----------SEDNPNQIRILAQTLTDGGVMDELIN-EELETFNSRWRELHE 1356 Query: 301 AVEDRVRQLHEA 312 R + L ++ Sbjct: 1357 EAVRRQKLLEQS 1368 Score = 50.4 bits (119), Expect = 8e-06 Identities = 38/164 (23%), Positives = 85/164 (51%), Gaps = 6/164 (3%) Query: 134 MSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHS 193 + L+ ++ L EQ GL L +E+ + ++ ++R + + EE+ W+KL+ Sbjct: 979 LGELQALQSSLQEQQ-SGLYYLSTTVKEMSKKAPSE-ISRKYQSEFEEIEGRWKKLSSQL 1036 Query: 194 ADWQRKIDETLERLQELQEATDELDLKLRQAEV-IKGSWQPVGDLLIDSLQDHLEKVKAL 252 + +K++E + +L+++Q L + + +V +K W +GD I L+ L++ + L Sbjct: 1037 VEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEWPALGDSEI--LKKQLKQCRLL 1094 Query: 253 RGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLST-LEDLNTRW 295 +I ++ +++ VN+ +++ L T L++LNT+W Sbjct: 1095 VSDIQTIQPSLNSVNEGGQKIKNEAEPEFASRLETELKELNTQW 1138 Score = 47.4 bits (111), Expect = 7e-05 Identities = 68/315 (21%), Positives = 125/315 (39%), Gaps = 53/315 (16%) Query: 17 EAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS-----HL 71 E H ++H + + Q + +G + + R + + + S RS HL Sbjct: 263 EEHFQLHHQMHYSQQITVSLAQGYERTSSPKPRFKSYAYTQAAYVTTSDPTRSPFPSQHL 322 Query: 72 EASSDQ------------WKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVH 119 EA D+ R +L+E+L WL +D L Q I D V+ Q H Sbjct: 323 EAPEDKSFGSSLMESEVNLDRYQTALEEVLSWLLSAEDTLQAQGEISNDVEVVKDQFHTH 382 Query: 120 RAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQA 179 + +L + + + L+ L G KL ++ EE +++Q Sbjct: 383 EGYMMDLTAHQGRVGNILQ------LGSKLIGTGKLSED------EETE------VQEQM 424 Query: 180 EEVNTEWEKLNLHSADWQRKIDETL-----ERLQELQEATDELDLKLRQAEVIKGSWQPV 234 +N+ WE L + S + Q + L ++L+EL + + + + R+ E +P+ Sbjct: 425 NLLNSRWECLRVASMEKQSNLHRVLMDLQNQKLKELNDWLTKTEERTRKMEE-----EPL 479 Query: 235 GDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLED---- 290 G L D L+ +++ K L+ + L++ VN L + + + + LE+ Sbjct: 480 GPDLED-LKRQVQQHKVLQED---LEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKV 535 Query: 291 LNTRWKLLQVAVEDR 305 L RW + EDR Sbjct: 536 LGDRWANICRWTEDR 550 Score = 42.4 bits (98), Expect = 0.002 Identities = 53/268 (19%), Positives = 109/268 (40%), Gaps = 26/268 (9%) Query: 47 QRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIG 106 Q + + +W +L + + LE ++ +++ +Q L W+ D L + P Sbjct: 1019 QSEFEEIEGRWKKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEWPAL 1078 Query: 107 GDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEE 166 GD ++KQ R +++T +P + S EG +K+ E PE Sbjct: 1079 GDSEILKKQLKQCRLLVSDIQTIQPSLNSV------------NEGGQKI---KNEAEPEF 1123 Query: 167 RAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQA-- 224 ++ L + +E+NT+W+ + + + LE+ LQ+ E+ + QA Sbjct: 1124 ASR-----LETELKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEE 1178 Query: 225 EVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYN 284 E ++ ++ D LQ +E++K + E + V + + + ++ Sbjct: 1179 EYLERDFEYKTP---DELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEA 1235 Query: 285 L-STLEDLNTRWKLLQVAVEDRVRQLHE 311 L LE L T ++ L + + + L E Sbjct: 1236 LKKELETLTTNYQWLCTRLNGKCKTLEE 1263 Score = 40.0 bits (92), Expect = 0.010 Identities = 70/329 (21%), Positives = 138/329 (41%), Gaps = 52/329 (15%) Query: 10 KDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 69 KDL+ + + + DV ++L + K+LR +DD + +N+N W + K+ + Sbjct: 2628 KDLR-QWQTNVDVANDL---ALKLLRDYS-ADDTRKVHMITENINASWRSIHKRVSEREA 2682 Query: 70 HLEASSDQWKRLHLSLQELLVWLQLKD------DELSRQAPIGGDFPAVQKQNDVHRAFK 123 LE + ++ L L++ L WL + + +R+ + D V++ + + Sbjct: 2683 ALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQ 2742 Query: 124 RELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELP------PEERAQNVTRLLRK 177 E++ V + E + L + LEG + R L E R +++ +R Sbjct: 2743 GEIEAHTDVYHNLDENSQKIL--RSLEGSDDAVLLQRRLDNMNFKWSELRKKSLN--IRS 2798 Query: 178 QAEEVNTEWEKLNLHSAD---WQRKIDETLER-------LQELQEATD-----ELDLKLR 222 E + +W++L+L + W + D+ L R +Q+ D + +LK + Sbjct: 2799 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 2858 Query: 223 QAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSP 282 + VI + + V L + + LEK+ E+ P +E +V L R+ Sbjct: 2859 E-PVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPP-EERAQNVTRLLRK---------- 2906 Query: 283 YNLSTLEDLNTRWKLLQVAVEDRVRQLHE 311 E++NT W+ L + D R++ E Sbjct: 2907 ----QAEEVNTEWEKLNLHSADWQRKIDE 2931 Score = 38.5 bits (88), Expect = 0.030 Identities = 111/514 (21%), Positives = 190/514 (36%), Gaps = 59/514 (11%) Query: 2 LHRKTYHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGS-DDAVLLQRRLDNMNFKWSEL 60 L K VK L E+ + L+E +L S S ++ L+ +L N +W ++ Sbjct: 2246 LKEKLEQVKLLVEELPLRQGILKQLNETGGPVLVSAPISPEEQDKLENKLKQTNLQWIKV 2305 Query: 61 RKKSLNIRSHLEASSDQWKRLHLSLQEL-------LVWLQLKDDELS--RQAPIGGDFP- 110 + + +EA +L L++L L+WL ++L Q G F Sbjct: 2306 SRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHLLLWLSPIRNQLEIYNQPNQEGPFDV 2365 Query: 111 -----AVQ-KQNDVHRAFKR--ELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPREL 162 AVQ KQ DV + L ++P + +E + + +L QE R Sbjct: 2366 QETEIAVQAKQPDVEEILSKGQHLYKEKPATQPVKRKLEDLSSEW--KAVNRLLQELRAK 2423 Query: 163 PPE----------ERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQE 212 P+ Q VT L+ + T KL + S+ ++ + + E Sbjct: 2424 QPDLAPGLTTIGASPTQTVT-LVTQPVVTKETAISKLEMPSS-LMLEVPALADFNRAWTE 2481 Query: 213 ATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQ 272 TD L L +VIK VGDL + + + + K KA ++ + + + A+ Sbjct: 2482 LTDWLSLL---DQVIKSQRVMVGDL--EDINEMIIKQKATMQDLEQRRPQLEELITAAQN 2536 Query: 273 LTTLGIQLSPYNLST--LEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQG 330 L + T +E + +W +Q +++R +QL+E +D S +L + Sbjct: 2537 LKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKD----STQWLEAKEEA 2592 Query: 331 PWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKAL 390 + K+ + T K+TE Q DL + + + L Sbjct: 2593 EQVLGQARAKLESW-KEGPYTVDAIQKKITETKQLAKDLRQWQTNV--------DVANDL 2643 Query: 391 CLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCL 450 L LL +A D H + +N I ++ LE+ H L PL ++ L Sbjct: 2644 ALKLLRDYSADDTRKVHMITENINA-SWRSIHKRVSEREAALEETHRLLQQFPLDLEKFL 2702 Query: 451 NWLLNVYDTGR-----TGRIRVLSFKTGIISLCK 479 WL T T + R+L G+ L K Sbjct: 2703 AWLTEAETTANVLQDATRKERLLEDSKGVKELMK 2736 Score = 35.0 bits (79), Expect = 0.33 Identities = 41/178 (23%), Positives = 78/178 (43%), Gaps = 10/178 (5%) Query: 715 LAEMENSNGSYLNDS-ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEE 773 L ++ + G L + ISP E E+ L Q Q + L + + I + ++ Sbjct: 2267 LKQLNETGGPVLVSAPISPEEQDKLENKLKQTNLQWIKVSRALPEKQGE----IEAQIKD 2322 Query: 774 RGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPT----SPQSPRDAEL 829 G+LE+ L DLEE+ +L ++ Q E P ++ T + P E+ Sbjct: 2323 LGQLEKKLEDLEEQLNHLLLWLSPIRNQLEIYNQPNQEGPFDVQETEIAVQAKQPDVEEI 2382 Query: 830 IAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPST 887 +++ + L + K + + LED + + ++ ++RL Q L Q + TT+ + T Sbjct: 2383 LSKGQHLYKEKPATQPVKRKLEDLSSEWKA-VNRLLQELRAKQPDLAPGLTTIGASPT 2439 Score = 32.3 bits (72), Expect = 2.2 Identities = 45/281 (16%), Positives = 104/281 (37%), Gaps = 36/281 (12%) Query: 2 LHRKTYHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVL---------LQRRLDN 52 L K+ + +Q ++ ++Y +L E ++ ++ V L R+ Sbjct: 1488 LETKSVEQEVVQSQLNHCVNLYKSLSEVKSEVEMVIKTGRQIVQKKQTENPKELDERVTA 1547 Query: 53 MNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAV 112 + ++EL K + LE +++ + L WL D EL++++ + G + Sbjct: 1548 LKLHYNELGAKVTERKQQLEKCLKLSRKMRKEMNVLTEWLAATDMELTKRSAVEGMPSNL 1607 Query: 113 QKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVT 172 + +A ++E++ ++ + S E T L E L ++ L Sbjct: 1608 DSEVAWGKATQKEIEKQKVHLKSITEVGEALKTV--LGKKETLVEDKLSL---------- 1655 Query: 173 RLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQ 232 +N+ W + + +W + E + ++ + D + + QA+ + + Sbjct: 1656 ---------LNSNWIAVTSRAEEWLNLLLEYQKHMETFDQNVDHITKWIIQADTLLDESE 1706 Query: 233 PVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQL 273 Q + +K L+ E+ ++ V D A L Sbjct: 1707 K------KKPQQKEDVLKRLKAELNDIRPKVDSTRDQAANL 1741 Score = 31.6 bits (70), Expect = 3.7 Identities = 42/234 (17%), Positives = 97/234 (41%), Gaps = 34/234 (14%) Query: 1 MLHRKTYHVKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSEL 60 +L R + D++ ++++ D NL N G L++ ++ +N +++ + Sbjct: 1716 VLKRLKAELNDIRPKVDSTRDQAANLMAN--------RGDHCRKLVEPQISELNHRFAAI 1767 Query: 61 R------KKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQK 114 K S+ ++ + +SD K L E+ + LK+++ ++ Sbjct: 1768 SHRIKTGKASIPLKELEQFNSDIQKLLEPLEAEIQQGVNLKEEDFNKD------------ 1815 Query: 115 QNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRL 174 N+ + +EL + + + R + ++ ++L Q + R+Q Sbjct: 1816 MNEDNEGTVKELLQRGDNLQQRITDER---KREEIKIKQQLLQTKHNALKDLRSQR---- 1868 Query: 175 LRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIK 228 RK+A E++ +W + + D + +D+ ++L L E DE +K E+ K Sbjct: 1869 -RKKALEISHQWYQYKRQADDLLKCLDDIEKKLASLPEPRDERKIKEIDRELQK 1921 >gi|5032309 dystrophin Dp140b isoform [Homo sapiens] Length = 1243 Score = 1881 bits (4873), Expect = 0.0 Identities = 934/936 (99%), Positives = 935/936 (99%) Query: 10 KDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 69 +DLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS Sbjct: 279 QDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 338 Query: 70 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 129 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK Sbjct: 339 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 398 Query: 130 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL 189 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL Sbjct: 399 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL 458 Query: 190 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV 249 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV Sbjct: 459 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV 518 Query: 250 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL 309 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL Sbjct: 519 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL 578 Query: 310 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 369 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL Sbjct: 579 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 638 Query: 370 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 429 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY Sbjct: 639 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 698 Query: 430 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL 489 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL Sbjct: 699 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL 758 Query: 490 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA 549 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA Sbjct: 759 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA 818 Query: 550 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ 609 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ Sbjct: 819 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ 878 Query: 610 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ 669 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ Sbjct: 879 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ 938 Query: 670 TVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS 729 TVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS Sbjct: 939 TVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS 998 Query: 730 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENR 789 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENR Sbjct: 999 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENR 1058 Query: 790 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI 849 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI Sbjct: 1059 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI 1118 Query: 850 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD 909 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD Sbjct: 1119 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD 1178 Query: 910 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRN 945 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRG N Sbjct: 1179 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHN 1214 Score = 67.8 bits (164), Expect = 5e-11 Identities = 53/235 (22%), Positives = 99/235 (42%), Gaps = 33/235 (14%) Query: 87 ELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTE 146 EL WL L D + Q + GD + + +A ++L+ + P Sbjct: 21 ELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQ-------------- 66 Query: 147 QPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLER 206 LE+L + L + Q ++ + E + +W+++ H + +++++E L+ Sbjct: 67 -----LEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKD 121 Query: 207 LQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHV 266 + EA +E + L QA SW+ G +D++Q + + K L ++ + NV Sbjct: 122 STQWLEAKEEAEQVLGQARAKLESWKE-GPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180 Query: 267 NDLARQLTTLGIQLSPYNLSTL-------EDLNTRWKLLQVAVEDRVRQLHEAHR 314 NDLA +L L Y+ E++N W+ + V +R L E HR Sbjct: 181 NDLALKL------LRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHR 229 Score = 40.0 bits (92), Expect = 0.010 Identities = 70/329 (21%), Positives = 138/329 (41%), Gaps = 52/329 (15%) Query: 10 KDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 69 KDL+ + + + DV ++L + K+LR +DD + +N+N W + K+ + Sbjct: 168 KDLR-QWQTNVDVANDL---ALKLLRDYS-ADDTRKVHMITENINASWRSIHKRVSEREA 222 Query: 70 HLEASSDQWKRLHLSLQELLVWLQLKD------DELSRQAPIGGDFPAVQKQNDVHRAFK 123 LE + ++ L L++ L WL + + +R+ + D V++ + + Sbjct: 223 ALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQ 282 Query: 124 RELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELP------PEERAQNVTRLLRK 177 E++ V + E + L + LEG + R L E R +++ +R Sbjct: 283 GEIEAHTDVYHNLDENSQKIL--RSLEGSDDAVLLQRRLDNMNFKWSELRKKSLN--IRS 338 Query: 178 QAEEVNTEWEKLNLHSAD---WQRKIDETLER-------LQELQEATD-----ELDLKLR 222 E + +W++L+L + W + D+ L R +Q+ D + +LK + Sbjct: 339 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 398 Query: 223 QAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSP 282 + VI + + V L + + LEK+ E+ P +E +V L R+ Sbjct: 399 E-PVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPP-EERAQNVTRLLRK---------- 446 Query: 283 YNLSTLEDLNTRWKLLQVAVEDRVRQLHE 311 E++NT W+ L + D R++ E Sbjct: 447 ----QAEEVNTEWEKLNLHSADWQRKIDE 471 >gi|5032311 dystrophin Dp140ab isoform [Homo sapiens] Length = 1230 Score = 1844 bits (4777), Expect = 0.0 Identities = 921/936 (98%), Positives = 922/936 (98%), Gaps = 13/936 (1%) Query: 10 KDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 69 +DLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS Sbjct: 279 QDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 338 Query: 70 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 129 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK Sbjct: 339 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 398 Query: 130 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL 189 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL Sbjct: 399 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL 458 Query: 190 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV 249 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV Sbjct: 459 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV 518 Query: 250 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL 309 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL Sbjct: 519 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL 578 Query: 310 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 369 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL Sbjct: 579 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 638 Query: 370 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 429 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY Sbjct: 639 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 698 Query: 430 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL 489 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL Sbjct: 699 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL 758 Query: 490 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA 549 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA Sbjct: 759 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA 818 Query: 550 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ 609 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ Sbjct: 819 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ 878 Query: 610 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ 669 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ Sbjct: 879 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ 938 Query: 670 TVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS 729 TVLEGDNMET PASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS Sbjct: 939 TVLEGDNMET-------------PASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS 985 Query: 730 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENR 789 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENR Sbjct: 986 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENR 1045 Query: 790 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI 849 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI Sbjct: 1046 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI 1105 Query: 850 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD 909 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD Sbjct: 1106 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD 1165 Query: 910 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRN 945 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRG N Sbjct: 1166 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHN 1201 Score = 67.8 bits (164), Expect = 5e-11 Identities = 53/235 (22%), Positives = 99/235 (42%), Gaps = 33/235 (14%) Query: 87 ELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTE 146 EL WL L D + Q + GD + + +A ++L+ + P Sbjct: 21 ELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQ-------------- 66 Query: 147 QPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLER 206 LE+L + L + Q ++ + E + +W+++ H + +++++E L+ Sbjct: 67 -----LEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKD 121 Query: 207 LQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHV 266 + EA +E + L QA SW+ G +D++Q + + K L ++ + NV Sbjct: 122 STQWLEAKEEAEQVLGQARAKLESWKE-GPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180 Query: 267 NDLARQLTTLGIQLSPYNLSTL-------EDLNTRWKLLQVAVEDRVRQLHEAHR 314 NDLA +L L Y+ E++N W+ + V +R L E HR Sbjct: 181 NDLALKL------LRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHR 229 Score = 40.0 bits (92), Expect = 0.010 Identities = 70/329 (21%), Positives = 138/329 (41%), Gaps = 52/329 (15%) Query: 10 KDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 69 KDL+ + + + DV ++L + K+LR +DD + +N+N W + K+ + Sbjct: 168 KDLR-QWQTNVDVANDL---ALKLLRDYS-ADDTRKVHMITENINASWRSIHKRVSEREA 222 Query: 70 HLEASSDQWKRLHLSLQELLVWLQLKD------DELSRQAPIGGDFPAVQKQNDVHRAFK 123 LE + ++ L L++ L WL + + +R+ + D V++ + + Sbjct: 223 ALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQ 282 Query: 124 RELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELP------PEERAQNVTRLLRK 177 E++ V + E + L + LEG + R L E R +++ +R Sbjct: 283 GEIEAHTDVYHNLDENSQKIL--RSLEGSDDAVLLQRRLDNMNFKWSELRKKSLN--IRS 338 Query: 178 QAEEVNTEWEKLNLHSAD---WQRKIDETLER-------LQELQEATD-----ELDLKLR 222 E + +W++L+L + W + D+ L R +Q+ D + +LK + Sbjct: 339 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 398 Query: 223 QAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSP 282 + VI + + V L + + LEK+ E+ P +E +V L R+ Sbjct: 399 E-PVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPP-EERAQNVTRLLRK---------- 446 Query: 283 YNLSTLEDLNTRWKLLQVAVEDRVRQLHE 311 E++NT W+ L + D R++ E Sbjct: 447 ----QAEEVNTEWEKLNLHSADWQRKIDE 471 >gi|5032313 dystrophin Dp140bc isoform [Homo sapiens] Length = 1133 Score = 1363 bits (3527), Expect = 0.0 Identities = 691/795 (86%), Positives = 710/795 (89%), Gaps = 52/795 (6%) Query: 10 KDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 69 +DLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS Sbjct: 279 QDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 338 Query: 70 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 129 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK Sbjct: 339 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 398 Query: 130 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL 189 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL Sbjct: 399 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL 458 Query: 190 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV 249 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV Sbjct: 459 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV 518 Query: 250 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL 309 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL Sbjct: 519 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL 578 Query: 310 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 369 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL Sbjct: 579 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 638 Query: 370 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 429 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY Sbjct: 639 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 698 Query: 430 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL 489 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL Sbjct: 699 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL 758 Query: 490 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA 549 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA Sbjct: 759 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA 818 Query: 550 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ 609 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ Sbjct: 819 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ 878 Query: 610 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ 669 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ Sbjct: 879 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ 938 Query: 670 TVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS 729 TVLEGDNMET + Q +D + EH L+ Sbjct: 939 TVLEGDNMETNL----------------QAEYDRLKQQHEHKG-------------LSPL 969 Query: 730 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLES----EERGELERILADLE 785 SP E + + P+SP + E+ + +G LE + LE Sbjct: 970 PSPPEMMP-------------------TSPQSPRDAELIAEAKLLRQHKGRLEARMQILE 1010 Query: 786 EENRNLQAEYDRLKQ 800 + N+ L+++ RL+Q Sbjct: 1011 DHNKQLESQLHRLRQ 1025 Score = 306 bits (785), Expect = 5e-83 Identities = 158/164 (96%), Positives = 159/164 (96%), Gaps = 2/164 (1%) Query: 784 LEEENR--NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 841 LE +N NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG Sbjct: 941 LEGDNMETNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 1000 Query: 842 RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 901 RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR Sbjct: 1001 RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 1060 Query: 902 VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRN 945 VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRG N Sbjct: 1061 VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHN 1104 Score = 67.8 bits (164), Expect = 5e-11 Identities = 53/235 (22%), Positives = 99/235 (42%), Gaps = 33/235 (14%) Query: 87 ELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTE 146 EL WL L D + Q + GD + + +A ++L+ + P Sbjct: 21 ELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQ-------------- 66 Query: 147 QPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLER 206 LE+L + L + Q ++ + E + +W+++ H + +++++E L+ Sbjct: 67 -----LEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKD 121 Query: 207 LQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHV 266 + EA +E + L QA SW+ G +D++Q + + K L ++ + NV Sbjct: 122 STQWLEAKEEAEQVLGQARAKLESWKE-GPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180 Query: 267 NDLARQLTTLGIQLSPYNLSTL-------EDLNTRWKLLQVAVEDRVRQLHEAHR 314 NDLA +L L Y+ E++N W+ + V +R L E HR Sbjct: 181 NDLALKL------LRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHR 229 Score = 40.0 bits (92), Expect = 0.010 Identities = 70/329 (21%), Positives = 138/329 (41%), Gaps = 52/329 (15%) Query: 10 KDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 69 KDL+ + + + DV ++L + K+LR +DD + +N+N W + K+ + Sbjct: 168 KDLR-QWQTNVDVANDL---ALKLLRDYS-ADDTRKVHMITENINASWRSIHKRVSEREA 222 Query: 70 HLEASSDQWKRLHLSLQELLVWLQLKD------DELSRQAPIGGDFPAVQKQNDVHRAFK 123 LE + ++ L L++ L WL + + +R+ + D V++ + + Sbjct: 223 ALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQ 282 Query: 124 RELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELP------PEERAQNVTRLLRK 177 E++ V + E + L + LEG + R L E R +++ +R Sbjct: 283 GEIEAHTDVYHNLDENSQKIL--RSLEGSDDAVLLQRRLDNMNFKWSELRKKSLN--IRS 338 Query: 178 QAEEVNTEWEKLNLHSAD---WQRKIDETLER-------LQELQEATD-----ELDLKLR 222 E + +W++L+L + W + D+ L R +Q+ D + +LK + Sbjct: 339 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 398 Query: 223 QAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSP 282 + VI + + V L + + LEK+ E+ P +E +V L R+ Sbjct: 399 E-PVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPP-EERAQNVTRLLRK---------- 446 Query: 283 YNLSTLEDLNTRWKLLQVAVEDRVRQLHE 311 E++NT W+ L + D R++ E Sbjct: 447 ----QAEEVNTEWEKLNLHSADWQRKIDE 471 >gi|5032307 dystrophin Dp140c isoform [Homo sapiens] Length = 1105 Score = 1343 bits (3475), Expect = 0.0 Identities = 668/697 (95%), Positives = 674/697 (96%), Gaps = 4/697 (0%) Query: 10 KDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 69 +DLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS Sbjct: 279 QDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 338 Query: 70 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 129 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK Sbjct: 339 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 398 Query: 130 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL 189 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL Sbjct: 399 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL 458 Query: 190 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV 249 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV Sbjct: 459 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV 518 Query: 250 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL 309 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL Sbjct: 519 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL 578 Query: 310 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 369 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL Sbjct: 579 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 638 Query: 370 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 429 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY Sbjct: 639 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 698 Query: 430 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL 489 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL Sbjct: 699 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL 758 Query: 490 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA 549 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA Sbjct: 759 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA 818 Query: 550 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ 609 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ Sbjct: 819 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ 878 Query: 610 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ 669 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ Sbjct: 879 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ 938 Query: 670 TV-LEGDNMETPVTLINFWPVDSAP---ASSPQLSHD 702 + E D ++ P+ S P +SPQ D Sbjct: 939 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRD 975 Score = 332 bits (851), Expect = 1e-90 Identities = 167/168 (99%), Positives = 168/168 (100%) Query: 789 RNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQ 848 +NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQ Sbjct: 938 QNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQ 997 Query: 849 ILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTS 908 ILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTS Sbjct: 998 ILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTS 1057 Query: 909 DSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM 956 DSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM Sbjct: 1058 DSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM 1105 Score = 67.8 bits (164), Expect = 5e-11 Identities = 53/235 (22%), Positives = 99/235 (42%), Gaps = 33/235 (14%) Query: 87 ELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTE 146 EL WL L D + Q + GD + + +A ++L+ + P Sbjct: 21 ELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQ-------------- 66 Query: 147 QPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLER 206 LE+L + L + Q ++ + E + +W+++ H + +++++E L+ Sbjct: 67 -----LEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKD 121 Query: 207 LQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHV 266 + EA +E + L QA SW+ G +D++Q + + K L ++ + NV Sbjct: 122 STQWLEAKEEAEQVLGQARAKLESWKE-GPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180 Query: 267 NDLARQLTTLGIQLSPYNLSTL-------EDLNTRWKLLQVAVEDRVRQLHEAHR 314 NDLA +L L Y+ E++N W+ + V +R L E HR Sbjct: 181 NDLALKL------LRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHR 229 Score = 40.0 bits (92), Expect = 0.010 Identities = 70/329 (21%), Positives = 138/329 (41%), Gaps = 52/329 (15%) Query: 10 KDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 69 KDL+ + + + DV ++L + K+LR +DD + +N+N W + K+ + Sbjct: 168 KDLR-QWQTNVDVANDL---ALKLLRDYS-ADDTRKVHMITENINASWRSIHKRVSEREA 222 Query: 70 HLEASSDQWKRLHLSLQELLVWLQLKD------DELSRQAPIGGDFPAVQKQNDVHRAFK 123 LE + ++ L L++ L WL + + +R+ + D V++ + + Sbjct: 223 ALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQ 282 Query: 124 RELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELP------PEERAQNVTRLLRK 177 E++ V + E + L + LEG + R L E R +++ +R Sbjct: 283 GEIEAHTDVYHNLDENSQKIL--RSLEGSDDAVLLQRRLDNMNFKWSELRKKSLN--IRS 338 Query: 178 QAEEVNTEWEKLNLHSAD---WQRKIDETLER-------LQELQEATD-----ELDLKLR 222 E + +W++L+L + W + D+ L R +Q+ D + +LK + Sbjct: 339 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 398 Query: 223 QAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSP 282 + VI + + V L + + LEK+ E+ P +E +V L R+ Sbjct: 399 E-PVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPP-EERAQNVTRLLRK---------- 446 Query: 283 YNLSTLEDLNTRWKLLQVAVEDRVRQLHE 311 E++NT W+ L + D R++ E Sbjct: 447 ----QAEEVNTEWEKLNLHSADWQRKIDE 471 >gi|110611228 utrophin [Homo sapiens] Length = 3433 Score = 1270 bits (3286), Expect = 0.0 Identities = 619/945 (65%), Positives = 760/945 (80%), Gaps = 9/945 (0%) Query: 9 VKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIR 68 ++D+Q EI+AH D++ ++D N QK++++L S++A +LQ RLD+MN +W++L+ KS +IR Sbjct: 2492 MQDIQAEIDAHNDIFKSIDGNRQKMVKALGNSEEATMLQHRLDDMNQRWNDLKAKSASIR 2551 Query: 69 SHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKT 128 +HLEAS+++W RL +SL+EL+ WL +KD+EL +Q PIGGD PA+Q Q D +A +RELK Sbjct: 2552 AHLEASAEKWNRLLMSLEELIKWLNMKDEELKKQMPIGGDVPALQLQYDHCKALRRELKE 2611 Query: 129 KEPVIMSTLETVRIFLTEQPLEGLE---KLYQEPRELPPEERAQNVTRLLRKQAEEVNTE 185 KE +++ ++ R+FL +QP+E E + Q EL PEERAQ + + +RKQ+ EV + Sbjct: 2612 KEYSVLNAVDQARVFLADQPIEAPEEPRRNLQSKTELTPEERAQKIAKAMRKQSSEVKEK 2671 Query: 186 WEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDH 245 WE LN +++WQ+++D+ LE+L++LQ A D+LD +++AE ++ W+PVGDLLIDSLQDH Sbjct: 2672 WESLNAVTSNWQKQVDKALEKLRDLQGAMDDLDADMKEAESVRNGWKPVGDLLIDSLQDH 2731 Query: 246 LEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDR 305 +EK+ A R EIAP+ V VNDL+ QL+ L + S L+DLN RWKLLQV+V+DR Sbjct: 2732 IEKIMAFREEIAPINFKVKTVNDLSSQLSPLDLHPSLKMSRQLDDLNMRWKLLQVSVDDR 2791 Query: 306 VRQLHEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQS 365 ++QL EAHRDFGP+SQHFLSTSVQ PW+R+IS NKVPYYINH+TQTTCWDHPKMTEL+QS Sbjct: 2792 LKQLQEAHRDFGPSSQHFLSTSVQLPWQRSISHNKVPYYINHQTQTTCWDHPKMTELFQS 2851 Query: 366 LADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCL 425 LADLNNVRFSAYRTA+K+RRLQKALCLDLL LS + QH L QNDQ + + +INCL Sbjct: 2852 LADLNNVRFSAYRTAIKIRRLQKALCLDLLELSTTNEIFKQHKLNQNDQLLSVPDVINCL 2911 Query: 426 TTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDK 485 TT YD LEQ H +LVNVPLCVDMCLNWLLNVYDTGRTG+IRV S K G++SL K LE+K Sbjct: 2912 TTTYDGLEQMHKDLVNVPLCVDMCLNWLLNVYDTGRTGKIRVQSLKIGLMSLSKGLLEEK 2971 Query: 486 YRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKP 545 YRYLFK+VA T CDQR+LGLLLHD+IQIPRQLGEVA+FGGSNIEPSVRSCFQ NNKP Sbjct: 2972 YRYLFKEVAGPTEMCDQRQLGLLLHDAIQIPRQLGEVAAFGGSNIEPSVRSCFQQNNNKP 3031 Query: 546 EIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNY 605 EI F+DWM LEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPI+GFRYRSLKHFNY Sbjct: 3032 EISVKEFIDWMHLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIVGFRYRSLKHFNY 3091 Query: 606 DICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGY 665 D+CQSCFFSGR AKGHK+HYPMVEYC PTTSGEDVRDF KVLKNKFR+K+YFAKHPR+GY Sbjct: 3092 DVCQSCFFSGRTAKGHKLHYPMVEYCIPTTSGEDVRDFTKVLKNKFRSKKYFAKHPRLGY 3151 Query: 666 LPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSY 725 LPVQTVLEGDN+ETP+TLI+ WP P+ SPQL HDDTHSRIE YA+RLA+ME +NGS+ Sbjct: 3152 LPVQTVLEGDNLETPITLISMWPEHYDPSQSPQLFHDDTHSRIEQYATRLAQMERTNGSF 3211 Query: 726 LNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLE 785 L DS S S++DEH LIQ YCQ+L +SP+SQP+SPAQIL S+E EERGELERI+ADLE Sbjct: 3212 LTDSSSTTGSVEDEHALIQQYCQTLGGESPVSQPQSPAQILKSVEREERGELERIIADLE 3271 Query: 786 EENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEA 845 EE RNLQ EY++LK QH +GL P+ SPPE + + + D+ELIAEAKLLRQHKGRLEA Sbjct: 3272 EEQRNLQVEYEQLKDQHLRRGL-PVGSPPESIISPHHTSEDSELIAEAKLLRQHKGRLEA 3330 Query: 846 RMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGS 905 RMQILEDHNKQLESQLHRLRQLLEQP++++++NG SP S Q S S + G Sbjct: 3331 RMQILEDHNKQLESQLHRLRQLLEQPESDSRINGV---SPWASPQHSALSYSLDPDASGP 3387 Query: 906 QTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKP 950 Q + G EDLL+PP DTST L EVMEQ++++FPS N P +P Sbjct: 3388 QFHQAAG-EDLLAPPHDTSTDLTEVMEQIHSTFPSC-CPNVPSRP 3430 Score = 62.4 bits (150), Expect = 2e-09 Identities = 59/233 (25%), Positives = 95/233 (40%), Gaps = 26/233 (11%) Query: 83 LSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRI 142 ++L+E+L WL +D Q I D V+ Q H AF EL + + S L+ Sbjct: 316 IALEEVLTWLLSAEDTFQEQDDISDDVEEVKDQFATHEAFMMELTAHQSSVGSVLQAGNQ 375 Query: 143 FLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDE 202 +T+ L E+ +++Q +N WE L + S D Q ++ + Sbjct: 376 LITQGTLSDEEEFE------------------IQEQMTLLNARWEALRVESMDRQSRLHD 417 Query: 203 TLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKEN 262 L LQ+ Q L L + + K P+ D + SLQ LE+ K+L+ + L+ Sbjct: 418 VLMELQKKQLQQLSAWLTLTEERIQKMETCPLDD-DVKSLQKLLEEHKSLQSD---LEAE 473 Query: 263 VSHVNDLARQLTTLGIQLSPYNLSTLED----LNTRWKLLQVAVEDRVRQLHE 311 VN L + + + LED L RW + E+R +L E Sbjct: 474 QVKVNSLTHMVVIVDENSGESATAILEDQLQKLGERWTAVCRWTEERWNRLQE 526 Score = 55.5 bits (132), Expect = 2e-07 Identities = 65/315 (20%), Positives = 129/315 (40%), Gaps = 41/315 (13%) Query: 15 EIEAH-TDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEA 73 E+ AH + V L +Q I + ++ +Q ++ +N +W LR +S++ +S L Sbjct: 358 ELTAHQSSVGSVLQAGNQLITQGTLSDEEEFEIQEQMTLLNARWEALRVESMDRQSRLHD 417 Query: 74 SSDQWKRLHLSLQELLVWLQLKDDELSRQ--APIGGDFPAVQKQNDVHRAFKRELKTKEP 131 + ++ L Q+L WL L ++ + + P+ D ++QK + H++ + +L+ ++ Sbjct: 418 VLMELQKKQL--QQLSAWLTLTEERIQKMETCPLDDDVKSLQKLLEEHKSLQSDLEAEQV 475 Query: 132 VIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNL 191 + S V I E ++ T +L Q +++ W + Sbjct: 476 KVNSLTHMVVIV--------------------DENSGESATAILEDQLQKLGERWTAVCR 515 Query: 192 HSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKA 251 + + ++ E QEL E L L + E + + + + +D E + Sbjct: 516 WTEERWNRLQEINILWQELLEEQCLLKAWLTEKE------EALNKVQTSNFKDQKELSVS 569 Query: 252 LRGEIAPLKENVSHVNDLARQLTTLGIQL---------SPYNLSTLEDLNTRWKLLQVAV 302 +R +A LKE++ QL+ +G + S S E+L RW L + Sbjct: 570 VR-RLAILKEDMEMKRQTLDQLSEIGQDVGQLLDNSKASKKINSDSEELTQRWDSLVQRL 628 Query: 303 EDRVRQLHEAHRDFG 317 ED Q+ +A G Sbjct: 629 EDSSNQVTQAVAKLG 643 Score = 47.4 bits (111), Expect = 7e-05 Identities = 62/299 (20%), Positives = 134/299 (44%), Gaps = 27/299 (9%) Query: 10 KDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELR---KKSLN 66 K L +E H L E ++ + +++ D L ++ D++ KW++L+ K L+ Sbjct: 951 KTLDEILENQKPALHKLAEETKALEKNVH-PDVEKLYKQEFDDVQGKWNKLKVLVSKDLH 1009 Query: 67 IRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKREL 126 + + + ++ +++ W+ D L +Q GD +Q+Q D AF E+ Sbjct: 1010 LLEEIALTLRAFEADSTVIEK---WMDGVKDFLMKQQAAQGDDAGLQRQLDQCSAFVNEI 1066 Query: 127 KTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEW 186 +T E + ++ + L P+ G+ K + + R + + + +++ + Q ++ Sbjct: 1067 ETIES-SLKNMKEIETNLRSGPVAGI-KTWVQTRLGDYQTQLEKLSKEIATQKSRLSESQ 1124 Query: 187 EKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHL 246 EK +A+ ++ + E E + + +E E D + + E ++ + + + D LQ + Sbjct: 1125 EK----AANLKKDLAEMQEWMTQAEEEYLERDFEYKSPEELESAVEEMKRAKEDVLQKEV 1180 Query: 247 EKVKALRGEIAPLKENVSHVNDLARQLTT-LGIQLSPYNL---------STLEDLNTRW 295 +VK L+ I L + V ++LT+ L + L Y L TLE++ + W Sbjct: 1181 -RVKILKDNIKLL---AAKVPSGGQELTSELNVVLENYQLLCNRIRGKCHTLEEVWSCW 1235 Score = 42.0 bits (97), Expect = 0.003 Identities = 56/250 (22%), Positives = 109/250 (43%), Gaps = 25/250 (10%) Query: 27 DENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLS-- 84 D QK+L GSDD ++ + + W L++ + ++ LEA +W+ + S Sbjct: 2395 DNVLQKLLEEY-GSDDTRNVKETTEYLKTSWINLKQSIADRQNALEA---EWRTVQASRR 2450 Query: 85 -LQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRA-FKRELKTKEPVIMSTLETVR- 141 L+ L W+Q + + A ++N + + RELK + I + ++ Sbjct: 2451 DLENFLKWIQ------EAETTVNVLVDASHRENALQDSILARELKQQMQDIQAEIDAHND 2504 Query: 142 IFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKID 201 IF + ++G + + + L E A +L+ + +++N W L SA + ++ Sbjct: 2505 IF---KSIDGNRQ--KMVKALGNSEEA----TMLQHRLDDMNQRWNDLKAKSASIRAHLE 2555 Query: 202 ETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKE 261 + E+ L + +EL L + P+G + +LQ + KALR E+ + Sbjct: 2556 ASAEKWNRLLMSLEELIKWLNMKDEELKKQMPIGG-DVPALQLQYDHCKALRRELKEKEY 2614 Query: 262 NVSHVNDLAR 271 +V + D AR Sbjct: 2615 SVLNAVDQAR 2624 Score = 40.8 bits (94), Expect = 0.006 Identities = 42/226 (18%), Positives = 99/226 (43%), Gaps = 19/226 (8%) Query: 9 VKDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIR 68 +K+++ +++ + + E ++ G + A+ ++ L +N KW + + + + Sbjct: 1910 LKNIKDQLDKLGEQIAVIHEKQPDVILEASGPE-AIQIRDTLTQLNAKWDRINRMYSDRK 1968 Query: 69 SHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAV-----QKQNDV----- 118 + + ++W++ H L +L W+ ++ L GG Q++ +V Sbjct: 1969 GCFDRAMEEWRQFHCDLNDLTQWITEAEELLVDTCAPGGSLDLEKARIHQQELEVGISSH 2028 Query: 119 HRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGL----EKLYQEPRELPPEERAQNVTRL 174 +F +T + ++ + FL E+ L GL + + E ++ P + ++ + Sbjct: 2029 QPSFAALNRTGDGIVQKLSQADGSFLKEK-LAGLNQRWDAIVAEVKDRQPRLKGESKQVM 2087 Query: 175 -LRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDL 219 R Q +E+ W H+ +R E E LQEL++ T E+++ Sbjct: 2088 KYRHQLDEIIC-WLTKAEHAMQ-KRSTTELGENLQELRDLTQEMEV 2131 Score = 37.4 bits (85), Expect = 0.067 Identities = 45/235 (19%), Positives = 95/235 (40%), Gaps = 29/235 (12%) Query: 9 VKDLQGEIEAHTDVYHNLDENSQK---------ILRSLEGSDDAVLLQRRLDNMNFKWSE 59 VK LQ +E H + +L+ K I+ G +L+ +L + +W+ Sbjct: 453 VKSLQKLLEEHKSLQSDLEAEQVKVNSLTHMVVIVDENSGESATAILEDQLQKLGERWTA 512 Query: 60 LRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVH 119 + + + + L+ + W+ L L WL K++ L++ VQ N Sbjct: 513 VCRWTEERWNRLQEINILWQELLEEQCLLKAWLTEKEEALNK----------VQTSN--- 559 Query: 120 RAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQA 179 FK + + V + + + Q L+ L ++ Q+ +L +A ++ + + Sbjct: 560 --FKDQKELSVSVRRLAILKEDMEMKRQTLDQLSEIGQDVGQLLDNSKA---SKKINSDS 614 Query: 180 EEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDEL--DLKLRQAEVIKGSWQ 232 EE+ W+ L D ++ + + +L Q +L +++R+ + K S Q Sbjct: 615 EELTQRWDSLVQRLEDSSNQVTQAVAKLGMSQIPQKDLLETVRVREQAITKKSKQ 669 Score = 35.4 bits (80), Expect = 0.26 Identities = 33/136 (24%), Positives = 61/136 (44%), Gaps = 4/136 (2%) Query: 769 LESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAE 828 ++ ++ E+++ L LE+E R D L Q + + E +PT + Sbjct: 719 MKMQDTSEMKKKLKALEKEQRERIPRADELNQTGQ---ILVEQMGKEGLPTEEIKNVLEK 775 Query: 829 LIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTS 888 + +E K + QH LE ++Q+ ED N + QL L ++++ + K + SS + Sbjct: 776 VSSEWKNVSQHLEDLERKIQLQEDINAYFK-QLDELEKVIKTKEEWVKHTSISESSRQSL 834 Query: 889 LQRSDSSQPMLLRVVG 904 DS Q L ++G Sbjct: 835 PSLKDSCQRELTNLLG 850 Score = 35.0 bits (79), Expect = 0.33 Identities = 58/334 (17%), Positives = 137/334 (41%), Gaps = 45/334 (13%) Query: 12 LQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHL 71 L+ ++E L E Q + + L+ S + + + + +W L ++ + + + Sbjct: 576 LKEDMEMKRQTLDQLSEIGQDVGQLLDNSKASKKINSDSEELTQRWDSLVQRLEDSSNQV 635 Query: 72 EASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRE------ 125 + + + ++LL +++++ +++++ P K+ +H + + Sbjct: 636 TQAVAKLGMSQIPQKDLLETVRVREQAITKKSKQELPPPPPPKKRQIHVDIEAKKKFDAI 695 Query: 126 --------LKTKEPVIMSTL-ETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVT---- 172 LK K + + + E +++ T + + L+ L +E RE P N T Sbjct: 696 SAELLNWILKWKTAIQTTEIKEYMKMQDTSEMKKKLKALEKEQRERIPRADELNQTGQIL 755 Query: 173 -----------RLLRKQAEEVNTEWEKLNLHSADWQRK------IDETLERLQELQEATD 215 ++ E+V++EW+ ++ H D +RK I+ ++L EL++ Sbjct: 756 VEQMGKEGLPTEEIKNVLEKVSSEWKNVSQHLEDLERKIQLQEDINAYFKQLDELEKVIK 815 Query: 216 ELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTT 275 + ++ + + S Q + L DS Q L + L +I + + S + +++ Sbjct: 816 TKEEWVKHTSISESSRQSLPSLK-DSCQRELTNLLGLHPKIEMARASCSAL--MSQPSAP 872 Query: 276 LGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL 309 +Q + R++ +Q AVEDR + L Sbjct: 873 DFVQRG------FDSFLGRYQAVQEAVEDRQQHL 900 Score = 34.3 bits (77), Expect = 0.57 Identities = 46/243 (18%), Positives = 90/243 (37%), Gaps = 13/243 (5%) Query: 67 IRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKREL 126 ++SH + L ++ EL WL L D L GD + K + K +L Sbjct: 2217 VQSHRTSEISIPADLDKTITELADWLVLIDQMLKSNIVTVGDVEEINKTVSRMKITKADL 2276 Query: 127 KTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPE--ERAQNVTRLLRKQAEEV-- 182 + + P + + + + E E + Q+ L ++Q E++ Sbjct: 2277 EQRHPQLDYVFTLAQNLKNKASSSDMRTAITEKLERVKNQWDGTQHGVELRQQQLEDMII 2336 Query: 183 -NTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDS 241 + +W+ + + RK + L LQ Q D L ++ +++ P GD ++ + Sbjct: 2337 DSLQWDDHREETEELMRKYEARLYILQ--QARRDPLTKQISDNQILLQELGP-GDGIVMA 2393 Query: 242 LQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVA 301 + L+K+ G ++ +V + L T I L L W+ +Q + Sbjct: 2394 FDNVLQKLLEEYG-----SDDTRNVKETTEYLKTSWINLKQSIADRQNALEAEWRTVQAS 2448 Query: 302 VED 304 D Sbjct: 2449 RRD 2451 Score = 32.0 bits (71), Expect = 2.8 Identities = 26/137 (18%), Positives = 62/137 (45%), Gaps = 5/137 (3%) Query: 175 LRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQA-EVIKGSWQP 233 +R ++N +W+++N +D + D +E ++ ++L + +A E++ + P Sbjct: 1946 IRDTLTQLNAKWDRINRMYSDRKGCFDRAMEEWRQFHCDLNDLTQWITEAEELLVDTCAP 2005 Query: 234 VGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVND-LARQLTTLGIQLSPYNLSTLEDLN 292 G L ++ + H ++++ P ++ D + ++L+ + L LN Sbjct: 2006 GGSLDLEKARIHQQELEVGISSHQPSFAALNRTGDGIVQKLSQAD---GSFLKEKLAGLN 2062 Query: 293 TRWKLLQVAVEDRVRQL 309 RW + V+DR +L Sbjct: 2063 QRWDAIVAEVKDRQPRL 2079 >gi|5032297 dystrophin Dp71 isoform [Homo sapiens] Length = 617 Score = 1240 bits (3208), Expect = 0.0 Identities = 610/610 (100%), Positives = 610/610 (100%) Query: 347 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 406 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ Sbjct: 8 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 67 Query: 407 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 466 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR Sbjct: 68 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 127 Query: 467 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 526 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG Sbjct: 128 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 187 Query: 527 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 586 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI Sbjct: 188 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 247 Query: 587 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 646 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV Sbjct: 248 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 307 Query: 647 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHS 706 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHS Sbjct: 308 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHS 367 Query: 707 RIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQIL 766 RIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQIL Sbjct: 368 RIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQIL 427 Query: 767 ISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRD 826 ISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRD Sbjct: 428 ISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRD 487 Query: 827 AELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPS 886 AELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPS Sbjct: 488 AELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPS 547 Query: 887 TSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNT 946 TSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNT Sbjct: 548 TSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNT 607 Query: 947 PGKPMREDTM 956 PGKPMREDTM Sbjct: 608 PGKPMREDTM 617 >gi|5032299 dystrophin Dp71b isoform [Homo sapiens] Length = 635 Score = 1214 bits (3142), Expect = 0.0 Identities = 598/599 (99%), Positives = 598/599 (99%) Query: 347 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 406 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ Sbjct: 8 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 67 Query: 407 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 466 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR Sbjct: 68 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 127 Query: 467 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 526 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG Sbjct: 128 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 187 Query: 527 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 586 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI Sbjct: 188 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 247 Query: 587 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 646 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV Sbjct: 248 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 307 Query: 647 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHS 706 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHS Sbjct: 308 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHS 367 Query: 707 RIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQIL 766 RIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQIL Sbjct: 368 RIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQIL 427 Query: 767 ISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRD 826 ISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRD Sbjct: 428 ISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRD 487 Query: 827 AELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPS 886 AELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPS Sbjct: 488 AELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPS 547 Query: 887 TSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRN 945 TSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRG N Sbjct: 548 TSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHN 606 >gi|5032301 dystrophin Dp71a isoform [Homo sapiens] Length = 604 Score = 1203 bits (3112), Expect = 0.0 Identities = 597/610 (97%), Positives = 597/610 (97%), Gaps = 13/610 (2%) Query: 347 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 406 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ Sbjct: 8 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 67 Query: 407 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 466 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR Sbjct: 68 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 127 Query: 467 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 526 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG Sbjct: 128 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 187 Query: 527 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 586 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI Sbjct: 188 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 247 Query: 587 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 646 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV Sbjct: 248 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 307 Query: 647 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHS 706 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET PASSPQLSHDDTHS Sbjct: 308 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET-------------PASSPQLSHDDTHS 354 Query: 707 RIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQIL 766 RIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQIL Sbjct: 355 RIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQIL 414 Query: 767 ISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRD 826 ISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRD Sbjct: 415 ISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRD 474 Query: 827 AELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPS 886 AELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPS Sbjct: 475 AELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPS 534 Query: 887 TSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNT 946 TSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNT Sbjct: 535 TSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNT 594 Query: 947 PGKPMREDTM 956 PGKPMREDTM Sbjct: 595 PGKPMREDTM 604 >gi|5032303 dystrophin Dp71ab isoform [Homo sapiens] Length = 622 Score = 1177 bits (3046), Expect = 0.0 Identities = 585/599 (97%), Positives = 585/599 (97%), Gaps = 13/599 (2%) Query: 347 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 406 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ Sbjct: 8 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 67 Query: 407 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 466 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR Sbjct: 68 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 127 Query: 467 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 526 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG Sbjct: 128 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 187 Query: 527 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 586 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI Sbjct: 188 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 247 Query: 587 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 646 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV Sbjct: 248 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 307 Query: 647 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHS 706 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET PASSPQLSHDDTHS Sbjct: 308 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET-------------PASSPQLSHDDTHS 354 Query: 707 RIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQIL 766 RIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQIL Sbjct: 355 RIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQIL 414 Query: 767 ISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRD 826 ISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRD Sbjct: 415 ISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRD 474 Query: 827 AELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPS 886 AELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPS Sbjct: 475 AELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPS 534 Query: 887 TSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRN 945 TSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRG N Sbjct: 535 TSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHN 593 >gi|148539558 dystrophin related protein 2 [Homo sapiens] Length = 957 Score = 996 bits (2574), Expect = 0.0 Identities = 494/892 (55%), Positives = 651/892 (72%), Gaps = 27/892 (3%) Query: 53 MNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAV 112 MN W+E++KKS N+R+ LEA SD +L L LQE++ WL KD+ELS Q P+ GD V Sbjct: 79 MNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVALV 138 Query: 113 QKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVT 172 Q++ + H AF E+K++ P I S LE+ + FL++ P E LE+ + E ++ P++R QN++ Sbjct: 139 QQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNLS 198 Query: 173 RLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQ 232 R + KQA + WEKL D R I+ TLE+L E+Q A +EL L QAE ++ +W+ Sbjct: 199 RFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRATWE 258 Query: 233 PVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLN 292 P+GDL IDSL +H++ +K + E +P+K+ V VNDLA QL + LS N LE +N Sbjct: 259 PIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMENSQALEQIN 318 Query: 293 TRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTT 352 RWK LQ +V +R++QL +AHRDFGP SQHFLS+SVQ PWERAISPNKVPYYINH+ QTT Sbjct: 319 VRWKQLQASVSERLKQLQDAHRDFGPGSQHFLSSSVQVPWERAISPNKVPYYINHQAQTT 378 Query: 353 CWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQN 412 CWDHPKMTELYQ+LADLNN++FSAYRTAMKLRR+QKAL LDL++L+ A + ++H+L+ + Sbjct: 379 CWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDLQAS 438 Query: 413 DQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKT 472 + MD++++I+CLT +Y+RLE+E LVNVPLCVDM LNWLLNV+D+GR+G++R LSFKT Sbjct: 439 EHVMDVVEVIHCLTALYERLEEERGILVNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKT 498 Query: 473 GIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEP 532 GI LC +++K +YLF QVA+S CDQR LG+LLH++IQ+PRQLGEVA+FGGSN+EP Sbjct: 499 GIACLCGTEVKEKLQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFGGSNVEP 558 Query: 533 SVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPI 592 SVRSCF+F+ KP IEA+ FL+W+ LEPQSMVWL VLHRV AE KHQ KC+IC++CPI Sbjct: 559 SVRSCFRFSTGKPVIEASQFLEWVNLEPQSMVWLAVLHRVTIAEQVKHQTKCSICRQCPI 618 Query: 593 IGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFR 652 GFRYRSLK FN DICQ+CF +GR +KG+K+HYP++EY TPTTS E++RDFA LKNKFR Sbjct: 619 KGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFR 678 Query: 653 TKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYA 712 +K YF+KHP+ GYLPVQ+VLE D ET PASSP H DTHSRIEH+A Sbjct: 679 SKHYFSKHPQRGYLPVQSVLEADYSET-------------PASSPMWPHADTHSRIEHFA 725 Query: 713 SRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLS--QPRSPAQILISLE 770 SRLAEME+ N S+ NDS+SP++SID++ L++H SP++ +P Q S+ Sbjct: 726 SRLAEMESQNCSFFNDSLSPDDSIDEDQYLLRH-------SSPITDREPAFGQQAPCSVA 778 Query: 771 SEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELI 830 +E +GEL++ILA LE+ENR LQ E RLK QHE + PS + + R+ EL+ Sbjct: 779 TESKGELQKILAHLEDENRILQGELRRLKWQHEE--AAEAPSLADGSTEAATDHRNEELL 836 Query: 831 AEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQ 890 AEA++LRQHK RLE RMQILEDHNKQLESQL RLR+LL QP E+ +G+ SS ++S Q Sbjct: 837 AEARILRQHKSRLETRMQILEDHNKQLESQLQRLRELLLQPPTESDGSGSAGSSLASSPQ 896 Query: 891 RSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSR 942 +S+ S P R G T D+ +D+ S QD S LE++ME+L ++FPS R Sbjct: 897 QSEGSHP---REKGQTTPDTEAADDVGSKSQDVSLCLEDIMEKLRHAFPSVR 945 >gi|5032305 dystrophin Dp40 isoform [Homo sapiens] Length = 340 Score = 693 bits (1789), Expect = 0.0 Identities = 333/333 (100%), Positives = 333/333 (100%) Query: 347 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 406 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ Sbjct: 8 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 67 Query: 407 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 466 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR Sbjct: 68 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 127 Query: 467 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 526 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG Sbjct: 128 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 187 Query: 527 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 586 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI Sbjct: 188 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 247 Query: 587 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 646 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV Sbjct: 248 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 307 Query: 647 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET 679 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET Sbjct: 308 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET 340 >gi|42717999 dystrobrevin alpha isoform 2 [Homo sapiens] Length = 686 Score = 212 bits (540), Expect = 1e-54 Identities = 171/590 (28%), Positives = 279/590 (47%), Gaps = 72/590 (12%) Query: 368 DLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQ--PMDILQIINCL 425 DL+ +R S YRTA KLR +QK L L+ + +AL ++ L D +++ ++ L Sbjct: 26 DLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPNTELNVSRLEAVL 85 Query: 426 TTIYDRLEQEH--NNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLE 483 +TI+ +L + + ++V + + LN+LL +D G+I V + K + +LC + Sbjct: 86 STIFYQLNKRMPTTHQIHVEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIM 145 Query: 484 DKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANN 543 DK RY+F ++ S+G R L + +++P + E SFG + E S RSCF + Sbjct: 146 DKLRYIFSMISDSSGVMVYGRYDQFLREVLKLPTAVFEGPSFGYT--EQSARSCF---SQ 200 Query: 544 KPEIEAALFLDWMRLEP--QSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLK 601 + ++ FLD + +P Q +VWLP+LHR+A E H +C+ C ++GFRYR + Sbjct: 201 QKKVTLNGFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQ 260 Query: 602 HFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHP 661 NY +CQ CF+ G H + M EY T+ + L ++ P Sbjct: 261 CHNYQLCQDCFWRGHAGGSHSNQHQMKEY---TSWKSPAKKLTNALSKSLSCAS--SREP 315 Query: 662 RMGYLPVQTVLEGDNMETPVTL---INFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEM 718 P D E P+ L ++ WP + + L S + +R + + Sbjct: 316 LHPMFP-------DQPEKPLNLAHIVDTWPPRPVTSMNDTLFSHSVPSSGSPFITR-SML 367 Query: 719 ENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQP---RSPAQILISLESEERG 775 E+SN +D+EH LI Y L +S SQP RS I ++++ + Sbjct: 368 ESSN------------RLDEEHRLIARYAARLAAESSSSQPPQQRSAPDISFTIDANK-- 413 Query: 776 ELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKL 835 + +++A+LE +NR + E RL+ +HE + P P + PT L+AE +L Sbjct: 414 QQRQLIAELENKNREILQEIQRLRLEHE-QASQPTPEKAQQNPT---------LLAELRL 463 Query: 836 LRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSS 895 LRQ K LE RM L++ ++L QL L +LL+ A G+ SSPS ++ R Sbjct: 464 LRQRKDELEQRMSALQESRRELMVQLEGLMKLLKTQGA-----GSPRSSPSHTISR---P 515 Query: 896 QPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRN 945 PM +R + ++ + PQD+ TG V + +F S RN Sbjct: 516 IPMPIRSASACSTPT-------HTPQDSLTG---VGGDVQEAFAQSSRRN 555 >gi|42718005 dystrobrevin alpha isoform 1 [Homo sapiens] Length = 743 Score = 206 bits (525), Expect = 6e-53 Identities = 180/629 (28%), Positives = 291/629 (46%), Gaps = 93/629 (14%) Query: 368 DLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQ--PMDILQIINCL 425 DL+ +R S YRTA KLR +QK L L+ + +AL ++ L D +++ ++ L Sbjct: 26 DLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPNTELNVSRLEAVL 85 Query: 426 TTIYDRLEQEH--NNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLE 483 +TI+ +L + + ++V + + LN+LL +D G+I V + K + +LC + Sbjct: 86 STIFYQLNKRMPTTHQIHVEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIM 145 Query: 484 DKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANN 543 DK RY+F ++ S+G R L + +++P + E SFG + E S RSCF + Sbjct: 146 DKLRYIFSMISDSSGVMVYGRYDQFLREVLKLPTAVFEGPSFGYT--EQSARSCF---SQ 200 Query: 544 KPEIEAALFLDWMRLEP--QSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLK 601 + ++ FLD + +P Q +VWLP+LHR+A E H +C+ C ++GFRYR + Sbjct: 201 QKKVTLNGFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQ 260 Query: 602 HFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAK-- 659 NY +CQ CF+ G H + M EY + + AK L N A Sbjct: 261 CHNYQLCQDCFWRGHAGGSHSNQHQMKEYTS-------WKSPAKKLTNALSKSLSCASSR 313 Query: 660 ---HPRMGYLPVQTVLEGDNMET----PVTLIN------FWPVDSAP---ASSPQLSHDD 703 HP P + + ++T PVT +N P +P SSP + Sbjct: 314 EPLHPMFPDQPEKPLNLAHIVDTWPPRPVTSMNDTLFSHSVPSSGSPFITRSSPPKDSEV 373 Query: 704 THSRI-----------------EHYASRLAEMENSNGSYLN-------DSISPNESIDDE 739 +++ + A RLA+ G Y+N + + +D+E Sbjct: 374 EQNKLLARAAPAFLKGKGIQYSLNVADRLADEHVLIGLYVNMLRNNPSCMLESSNRLDEE 433 Query: 740 HLLIQHYCQSLNQDSPLSQP---RSPAQILISLESEERGELERILADLEEENRNLQAEYD 796 H LI Y L +S SQP RS I ++++ + + +++A+LE +NR + E Sbjct: 434 HRLIARYAARLAAESSSSQPPQQRSAPDISFTIDANK--QQRQLIAELENKNREILQEIQ 491 Query: 797 RLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQ 856 RL+ +HE + P P + PT L+AE +LLRQ K LE RM L++ ++ Sbjct: 492 RLRLEHE-QASQPTPEKAQQNPT---------LLAELRLLRQRKDELEQRMSALQESRRE 541 Query: 857 LESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDL 916 L QL L +LL+ A G+ SSPS ++ R PM +R + ++ + Sbjct: 542 LMVQLEGLMKLLKTQGA-----GSPRSSPSHTISR---PIPMPIRSASACSTPT------ 587 Query: 917 LSPPQDTSTGLEEVMEQLNNSFPSSRGRN 945 PQD+ TG V + +F S RN Sbjct: 588 -HTPQDSLTG---VGGDVQEAFAQSSRRN 612 >gi|42717997 dystrobrevin alpha isoform 5 [Homo sapiens] Length = 513 Score = 206 bits (525), Expect = 6e-53 Identities = 152/523 (29%), Positives = 253/523 (48%), Gaps = 54/523 (10%) Query: 368 DLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQ--PMDILQIINCL 425 DL+ +R S YRTA KLR +QK L L+ + +AL ++ L D +++ ++ L Sbjct: 26 DLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPNTELNVSRLEAVL 85 Query: 426 TTIYDRLEQEH--NNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLE 483 +TI+ +L + + ++V + + LN+LL +D G+I V + K + +LC + Sbjct: 86 STIFYQLNKRMPTTHQIHVEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIM 145 Query: 484 DKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANN 543 DK RY+F ++ S+G R L + +++P + E SFG + E S RSCF + Sbjct: 146 DKLRYIFSMISDSSGVMVYGRYDQFLREVLKLPTAVFEGPSFGYT--EQSARSCF---SQ 200 Query: 544 KPEIEAALFLDWMRLEP--QSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLK 601 + ++ FLD + +P Q +VWLP+LHR+A E H +C+ C ++GFRYR + Sbjct: 201 QKKVTLNGFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQ 260 Query: 602 HFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHP 661 NY +CQ CF+ G H + M EY T+ + L ++ P Sbjct: 261 CHNYQLCQDCFWRGHAGGSHSNQHQMKEY---TSWKSPAKKLTNALSKSLSCAS--SREP 315 Query: 662 RMGYLPVQTVLEGDNMETPVTL---INFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEM 718 P D E P+ L ++ WP + + L S + +R + + Sbjct: 316 LHPMFP-------DQPEKPLNLAHIVDTWPPRPVTSMNDTLFSHSVPSSGSPFITR-SML 367 Query: 719 ENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQP---RSPAQILISLESEERG 775 E+SN +D+EH LI Y L +S SQP RS I ++++ + Sbjct: 368 ESSN------------RLDEEHRLIARYAARLAAESSSSQPPQQRSAPDISFTIDANK-- 413 Query: 776 ELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKL 835 + +++A+LE +NR + E RL+ +HE + P P + PT L+AE +L Sbjct: 414 QQRQLIAELENKNREILQEIQRLRLEHE-QASQPTPEKAQQNPT---------LLAELRL 463 Query: 836 LRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVN 878 LRQ K LE RM L++ ++L QL L +LL++ + + V+ Sbjct: 464 LRQRKDELEQRMSALQESRRELMVQLEGLMKLLKEEELKQGVS 506 >gi|42718003 dystrobrevin alpha isoform 3 [Homo sapiens] Length = 570 Score = 201 bits (510), Expect = 4e-51 Identities = 161/562 (28%), Positives = 265/562 (47%), Gaps = 75/562 (13%) Query: 368 DLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQ--PMDILQIINCL 425 DL+ +R S YRTA KLR +QK L L+ + +AL ++ L D +++ ++ L Sbjct: 26 DLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPNTELNVSRLEAVL 85 Query: 426 TTIYDRLEQEH--NNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLE 483 +TI+ +L + + ++V + + LN+LL +D G+I V + K + +LC + Sbjct: 86 STIFYQLNKRMPTTHQIHVEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIM 145 Query: 484 DKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANN 543 DK RY+F ++ S+G R L + +++P + E SFG + E S RSCF + Sbjct: 146 DKLRYIFSMISDSSGVMVYGRYDQFLREVLKLPTAVFEGPSFGYT--EQSARSCF---SQ 200 Query: 544 KPEIEAALFLDWMRLEP--QSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLK 601 + ++ FLD + +P Q +VWLP+LHR+A E H +C+ C ++GFRYR + Sbjct: 201 QKKVTLNGFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQ 260 Query: 602 HFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAK-- 659 NY +CQ CF+ G H + M EY + + AK L N A Sbjct: 261 CHNYQLCQDCFWRGHAGGSHSNQHQMKEYTS-------WKSPAKKLTNALSKSLSCASSR 313 Query: 660 ---HPRMGYLPVQTVLEGDNMET----PVTLIN------FWPVDSAP---ASSPQLSHDD 703 HP P + + ++T PVT +N P +P SSP + Sbjct: 314 EPLHPMFPDQPEKPLNLAHIVDTWPPRPVTSMNDTLFSHSVPSSGSPFITRSSPPKDSEV 373 Query: 704 THSRI-----------------EHYASRLAEMENSNGSYLN-------DSISPNESIDDE 739 +++ + A RLA+ G Y+N + + +D+E Sbjct: 374 EQNKLLARAAPAFLKGKGIQYSLNVADRLADEHVLIGLYVNMLRNNPSCMLESSNRLDEE 433 Query: 740 HLLIQHYCQSLNQDSPLSQP---RSPAQILISLESEERGELERILADLEEENRNLQAEYD 796 H LI Y L +S SQP RS I ++++ + + +++A+LE +NR + E Sbjct: 434 HRLIARYAARLAAESSSSQPPQQRSAPDISFTIDANK--QQRQLIAELENKNREILQEIQ 491 Query: 797 RLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQ 856 RL+ +HE + P P + PT L+AE +LLRQ K LE RM L++ ++ Sbjct: 492 RLRLEHE-QASQPTPEKAQQNPT---------LLAELRLLRQRKDELEQRMSALQESRRE 541 Query: 857 LESQLHRLRQLLEQPQAEAKVN 878 L QL L +LL++ + + V+ Sbjct: 542 LMVQLEGLMKLLKEEELKQGVS 563 >gi|42718001 dystrobrevin alpha isoform 4 [Homo sapiens] Length = 567 Score = 199 bits (506), Expect = 1e-50 Identities = 161/559 (28%), Positives = 263/559 (47%), Gaps = 72/559 (12%) Query: 368 DLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQ--PMDILQIINCL 425 DL+ +R S YRTA KLR +QK L L+ + +AL ++ L D +++ ++ L Sbjct: 26 DLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPNTELNVSRLEAVL 85 Query: 426 TTIYDRLEQEH--NNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLE 483 +TI+ +L + + ++V + + LN+LL +D G+I V + K + +LC + Sbjct: 86 STIFYQLNKRMPTTHQIHVEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIM 145 Query: 484 DKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANN 543 DK RY+F ++ S+G R L + +++P + E SFG + E S RSCF + Sbjct: 146 DKLRYIFSMISDSSGVMVYGRYDQFLREVLKLPTAVFEGPSFGYT--EQSARSCF---SQ 200 Query: 544 KPEIEAALFLDWMRLEP--QSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLK 601 + ++ FLD + +P Q +VWLP+LHR+A E H +C+ C ++GFRYR + Sbjct: 201 QKKVTLNGFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQ 260 Query: 602 HFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAK-- 659 NY +CQ CF+ G H + M EY + + AK L N A Sbjct: 261 CHNYQLCQDCFWRGHAGGSHSNQHQMKEYTS-------WKSPAKKLTNALSKSLSCASSR 313 Query: 660 ---HPRMGYLPVQTV-LEGDNMETPVTLIN------FWPVDSAP---ASSPQLSHDDTHS 706 HP P + + L PVT +N P +P SSP + + Sbjct: 314 EPLHPMFPDQPEKPLNLAHIVPPRPVTSMNDTLFSHSVPSSGSPFITRSSPPKDSEVEQN 373 Query: 707 RI-----------------EHYASRLAEMENSNGSYLN-------DSISPNESIDDEHLL 742 ++ + A RLA+ G Y+N + + +D+EH L Sbjct: 374 KLLARAAPAFLKGKGIQYSLNVADRLADEHVLIGLYVNMLRNNPSCMLESSNRLDEEHRL 433 Query: 743 IQHYCQSLNQDSPLSQP---RSPAQILISLESEERGELERILADLEEENRNLQAEYDRLK 799 I Y L +S SQP RS I ++++ + + +++A+LE +NR + E RL+ Sbjct: 434 IARYAARLAAESSSSQPPQQRSAPDISFTIDANK--QQRQLIAELENKNREILQEIQRLR 491 Query: 800 QQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLES 859 +HE + P P + PT L+AE +LLRQ K LE RM L++ ++L Sbjct: 492 LEHE-QASQPTPEKAQQNPT---------LLAELRLLRQRKDELEQRMSALQESRRELMV 541 Query: 860 QLHRLRQLLEQPQAEAKVN 878 QL L +LL++ + + V+ Sbjct: 542 QLEGLMKLLKEEELKQGVS 560 >gi|11276069 dystrobrevin, beta isoform 1 [Homo sapiens] Length = 627 Score = 195 bits (495), Expect = 2e-49 Identities = 158/567 (27%), Positives = 270/567 (47%), Gaps = 50/567 (8%) Query: 372 VRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDIL--QIINCLTTIY 429 +R S YRTA KLR +QK L L+ + +A + L D +I ++ +++IY Sbjct: 30 IRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETVISSIY 89 Query: 430 DRLEQE--HNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYR 487 +L + + ++V + + LN+++ YD+ G++ V S K + ++C + DK R Sbjct: 90 YQLNKRLPSTHQISVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLR 149 Query: 488 YLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEI 547 Y+F Q++ S G + L + +++P + E SFG + E SVR+CF + +I Sbjct: 150 YVFSQMSDSNGLMIFSKFDQFLKEVLKLPTAVFEGPSFGYT--EHSVRTCFP---QQRKI 204 Query: 548 EAALFLDWMRLEP--QSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNY 605 +FLD M +P Q +VWLP++HR+A E H +C+ C+ ++GFRYR + NY Sbjct: 205 MLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCRCESMMGFRYRCQQCHNY 264 Query: 606 DICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGY 665 +CQ+CF+ G H + M E+ + + + + T+ HP Sbjct: 265 QLCQNCFWRGHAGGPHSNQHQMKEHSSWKSPAKKLSHAISKSLGCVPTRE--PPHPVFPE 322 Query: 666 LPVQTV-LEGDNMETPVTLINFWPVDSAPASSP------QLSHD------DTHSRIEHYA 712 P + + L P+T +N V + P Q S D D H+ I Y Sbjct: 323 QPEKPLDLAHIVPPRPLTNMNDTMVSHMSSGVPTPTKRLQYSQDIPSHLADEHALIASYV 382 Query: 713 SRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESE 772 +RL + + + DS S +D+EH LI Y L ++ + R P + + ++ Sbjct: 383 ARL-----QHCARVLDSPS---RLDEEHRLIARYAARLAAEAG-NVTRPPTDLSFNFDAN 433 Query: 773 ERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAE 832 + + +++A+LE +NR + E RL+ +HE + P P + PT L+AE Sbjct: 434 K--QQRQLIAELENKNREILQEIQRLRLEHE-QASQPTPEKAQQNPT---------LLAE 481 Query: 833 AKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTS-LQR 891 +LLRQ K LE RM L++ ++L QL L +LL++ + + T SP TS Sbjct: 482 LRLLRQRKDELEQRMSALQESRRELMVQLEELMKLLKEEEQKQAAQAT--GSPHTSPTHG 539 Query: 892 SDSSQPMLLRVVGSQTSDSMGEEDLLS 918 PM +R + ++ + +D LS Sbjct: 540 GGRPMPMPVRSTSAGSTPTHCPQDSLS 566 >gi|37577099 dystrobrevin, beta isoform 2 [Homo sapiens] Length = 597 Score = 195 bits (495), Expect = 2e-49 Identities = 158/567 (27%), Positives = 270/567 (47%), Gaps = 50/567 (8%) Query: 372 VRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDIL--QIINCLTTIY 429 +R S YRTA KLR +QK L L+ + +A + L D +I ++ +++IY Sbjct: 30 IRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETVISSIY 89 Query: 430 DRLEQE--HNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYR 487 +L + + ++V + + LN+++ YD+ G++ V S K + ++C + DK R Sbjct: 90 YQLNKRLPSTHQISVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLR 149 Query: 488 YLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEI 547 Y+F Q++ S G + L + +++P + E SFG + E SVR+CF + +I Sbjct: 150 YVFSQMSDSNGLMIFSKFDQFLKEVLKLPTAVFEGPSFGYT--EHSVRTCFP---QQRKI 204 Query: 548 EAALFLDWMRLEP--QSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNY 605 +FLD M +P Q +VWLP++HR+A E H +C+ C+ ++GFRYR + NY Sbjct: 205 MLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCRCESMMGFRYRCQQCHNY 264 Query: 606 DICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGY 665 +CQ+CF+ G H + M E+ + + + + T+ HP Sbjct: 265 QLCQNCFWRGHAGGPHSNQHQMKEHSSWKSPAKKLSHAISKSLGCVPTRE--PPHPVFPE 322 Query: 666 LPVQTV-LEGDNMETPVTLINFWPVDSAPASSP------QLSHD------DTHSRIEHYA 712 P + + L P+T +N V + P Q S D D H+ I Y Sbjct: 323 QPEKPLDLAHIVPPRPLTNMNDTMVSHMSSGVPTPTKRLQYSQDIPSHLADEHALIASYV 382 Query: 713 SRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESE 772 +RL + + + DS S +D+EH LI Y L ++ + R P + + ++ Sbjct: 383 ARL-----QHCARVLDSPS---RLDEEHRLIARYAARLAAEAG-NVTRPPTDLSFNFDAN 433 Query: 773 ERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAE 832 + + +++A+LE +NR + E RL+ +HE + P P + PT L+AE Sbjct: 434 K--QQRQLIAELENKNREILQEIQRLRLEHE-QASQPTPEKAQQNPT---------LLAE 481 Query: 833 AKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTS-LQR 891 +LLRQ K LE RM L++ ++L QL L +LL++ + + T SP TS Sbjct: 482 LRLLRQRKDELEQRMSALQESRRELMVQLEELMKLLKEEEQKQAAQAT--GSPHTSPTHG 539 Query: 892 SDSSQPMLLRVVGSQTSDSMGEEDLLS 918 PM +R + ++ + +D LS Sbjct: 540 GGRPMPMPVRSTSAGSTPTHCPQDSLS 566 >gi|37577095 dystrobrevin, beta isoform 4 [Homo sapiens] Length = 609 Score = 195 bits (495), Expect = 2e-49 Identities = 158/567 (27%), Positives = 270/567 (47%), Gaps = 50/567 (8%) Query: 372 VRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDIL--QIINCLTTIY 429 +R S YRTA KLR +QK L L+ + +A + L D +I ++ +++IY Sbjct: 30 IRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETVISSIY 89 Query: 430 DRLEQE--HNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYR 487 +L + + ++V + + LN+++ YD+ G++ V S K + ++C + DK R Sbjct: 90 YQLNKRLPSTHQISVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLR 149 Query: 488 YLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEI 547 Y+F Q++ S G + L + +++P + E SFG + E SVR+CF + +I Sbjct: 150 YVFSQMSDSNGLMIFSKFDQFLKEVLKLPTAVFEGPSFGYT--EHSVRTCFP---QQRKI 204 Query: 548 EAALFLDWMRLEP--QSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNY 605 +FLD M +P Q +VWLP++HR+A E H +C+ C+ ++GFRYR + NY Sbjct: 205 MLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCRCESMMGFRYRCQQCHNY 264 Query: 606 DICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGY 665 +CQ+CF+ G H + M E+ + + + + T+ HP Sbjct: 265 QLCQNCFWRGHAGGPHSNQHQMKEHSSWKSPAKKLSHAISKSLGCVPTRE--PPHPVFPE 322 Query: 666 LPVQTV-LEGDNMETPVTLINFWPVDSAPASSP------QLSHD------DTHSRIEHYA 712 P + + L P+T +N V + P Q S D D H+ I Y Sbjct: 323 QPEKPLDLAHIVPPRPLTNMNDTMVSHMSSGVPTPTKRLQYSQDIPSHLADEHALIASYV 382 Query: 713 SRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESE 772 +RL + + + DS S +D+EH LI Y L ++ + R P + + ++ Sbjct: 383 ARL-----QHCARVLDSPS---RLDEEHRLIARYAARLAAEAG-NVTRPPTDLSFNFDAN 433 Query: 773 ERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAE 832 + + +++A+LE +NR + E RL+ +HE + P P + PT L+AE Sbjct: 434 K--QQRQLIAELENKNREILQEIQRLRLEHE-QASQPTPEKAQQNPT---------LLAE 481 Query: 833 AKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTS-LQR 891 +LLRQ K LE RM L++ ++L QL L +LL++ + + T SP TS Sbjct: 482 LRLLRQRKDELEQRMSALQESRRELMVQLEELMKLLKEEEQKQAAQAT--GSPHTSPTHG 539 Query: 892 SDSSQPMLLRVVGSQTSDSMGEEDLLS 918 PM +R + ++ + +D LS Sbjct: 540 GGRPMPMPVRSTSAGSTPTHCPQDSLS 566 >gi|15147341 dystrobrevin, beta isoform 3 [Homo sapiens] Length = 567 Score = 192 bits (489), Expect = 1e-48 Identities = 152/554 (27%), Positives = 263/554 (47%), Gaps = 54/554 (9%) Query: 372 VRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDIL--QIINCLTTIY 429 +R S YRTA KLR +QK L L+ + +A + L D +I ++ +++IY Sbjct: 30 IRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETVISSIY 89 Query: 430 DRLEQE--HNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYR 487 +L + + ++V + + LN+++ YD+ G++ V S K + ++C + DK R Sbjct: 90 YQLNKRLPSTHQISVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLR 149 Query: 488 YLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEI 547 Y+F Q++ S G + L + +++P + E SFG + E SVR+CF + +I Sbjct: 150 YVFSQMSDSNGLMIFSKFDQFLKEVLKLPTAVFEGPSFGYT--EHSVRTCFP---QQRKI 204 Query: 548 EAALFLDWMRLEP--QSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNY 605 +FLD M +P Q +VWLP++HR+A E H +C+ C+ ++GFRYR + NY Sbjct: 205 MLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCRCESMMGFRYRCQQCHNY 264 Query: 606 DICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGY 665 +CQ+CF+ G H + M E+ + + + K A +G Sbjct: 265 QLCQNCFWRGHAGGPHSNQHQMKEHSSWKSPAK---------------KLSHAISKSLGC 309 Query: 666 LPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSY 725 +P + E P P+D A P+ + + + H +S + S Sbjct: 310 VPTREPPHPVFPEQPEK-----PLDLAHIVPPRPLTNMNDTMVSHMSSGVPTPTKS---- 360 Query: 726 LNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLE 785 + DS S +D+EH LI Y L ++ + R P + + ++ + + +++A+LE Sbjct: 361 VLDSPS---RLDEEHRLIARYAARLAAEAG-NVTRPPTDLSFNFDANK--QQRQLIAELE 414 Query: 786 EENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEA 845 +NR + E RL+ +HE + P P + PT L+AE +LLRQ K LE Sbjct: 415 NKNREILQEIQRLRLEHE-QASQPTPEKAQQNPT---------LLAELRLLRQRKDELEQ 464 Query: 846 RMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTS-LQRSDSSQPMLLRVVG 904 RM L++ ++L QL L +LL++ + + T SP TS PM +R Sbjct: 465 RMSALQESRRELMVQLEELMKLLKEEEQKQAAQAT--GSPHTSPTHGGGRPMPMPVRSTS 522 Query: 905 SQTSDSMGEEDLLS 918 + ++ + +D LS Sbjct: 523 AGSTPTHCPQDSLS 536 >gi|37577097 dystrobrevin, beta isoform 5 [Homo sapiens] Length = 560 Score = 190 bits (482), Expect = 6e-48 Identities = 152/553 (27%), Positives = 264/553 (47%), Gaps = 59/553 (10%) Query: 372 VRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDIL--QIINCLTTIY 429 +R S YRTA KLR +QK L L+ + +A + L D +I ++ +++IY Sbjct: 30 IRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETVISSIY 89 Query: 430 DRLEQE--HNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYR 487 +L + + ++V + + LN+++ YD+ G++ V S K + ++C + DK R Sbjct: 90 YQLNKRLPSTHQISVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLR 149 Query: 488 YLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEI 547 Y+F Q++ S G + L + +++P + E SFG + E SVR+CF + +I Sbjct: 150 YVFSQMSDSNGLMIFSKFDQFLKEVLKLPTAVFEGPSFGYT--EHSVRTCFP---QQRKI 204 Query: 548 EAALFLDWMRLEP--QSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNY 605 +FLD M +P Q +VWLP++HR+A E H +C+ C+ ++GFRYR + NY Sbjct: 205 MLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCRCESMMGFRYRCQQCHNY 264 Query: 606 DICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGY 665 +CQ+CF+ G H + M E+ + + + K A +G Sbjct: 265 QLCQNCFWRGHAGGPHSNQHQMKEHSSWKSPAK---------------KLSHAISKSLGC 309 Query: 666 LPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSY 725 +P + E P P+D A P+ + + + H +S + S Sbjct: 310 VPTREPPHPVFPEQPEK-----PLDLAHIVPPRPLTNMNDTMVSHMSSGVPTPTKS---- 360 Query: 726 LNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLE 785 + DS S +D+EH LI Y L ++ + R P + + ++ + + +++A+LE Sbjct: 361 VLDSPS---RLDEEHRLIARYAARLAAEAG-NVTRPPTDLSFNFDANK--QQRQLIAELE 414 Query: 786 EENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEA 845 +NR + E RL+ +HE + P P + PT L+AE +LLRQ K LE Sbjct: 415 NKNREILQEIQRLRLEHE-QASQPTPEKAQQNPT---------LLAELRLLRQRKDELEQ 464 Query: 846 RMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGS 905 RM L++ ++L QL L +LL +A+ G+ +SP+ R PM +R + Sbjct: 465 RMSALQESRRELMVQLEELMKLL-----KAQATGSPHTSPTHGGGR---PMPMPVRSTSA 516 Query: 906 QTSDSMGEEDLLS 918 ++ + +D LS Sbjct: 517 GSTPTHCPQDSLS 529 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.132 0.387 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 37,662,794 Number of Sequences: 37866 Number of extensions: 1765150 Number of successful extensions: 11661 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 127 Number of HSP's successfully gapped in prelim test: 490 Number of HSP's that attempted gapping in prelim test: 8783 Number of HSP's gapped (non-prelim): 2762 length of query: 956 length of database: 18,247,518 effective HSP length: 112 effective length of query: 844 effective length of database: 14,006,526 effective search space: 11821507944 effective search space used: 11821507944 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.