BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|5032293 dystrophin Dp140 isoform [Homo sapiens] (1225 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|5032281 dystrophin Dp427c isoform [Homo sapiens] 2452 0.0 gi|5032291 dystrophin Dp260-2 isoform [Homo sapiens] 2452 0.0 gi|150036268 dystrophin Dp260-1 isoform [Homo sapiens] 2452 0.0 gi|5032315 dystrophin Dp427p2 isoform [Homo sapiens] 2452 0.0 gi|5032287 dystrophin Dp427p1 isoform [Homo sapiens] 2452 0.0 gi|5032293 dystrophin Dp140 isoform [Homo sapiens] 2452 0.0 gi|5032285 dystrophin Dp427l isoform [Homo sapiens] 2452 0.0 gi|5032283 dystrophin Dp427m isoform [Homo sapiens] 2452 0.0 gi|5032309 dystrophin Dp140b isoform [Homo sapiens] 2427 0.0 gi|5032311 dystrophin Dp140ab isoform [Homo sapiens] 2390 0.0 gi|5032313 dystrophin Dp140bc isoform [Homo sapiens] 1908 0.0 gi|5032295 dystrophin Dp116 isoform [Homo sapiens] 1907 0.0 gi|5032307 dystrophin Dp140c isoform [Homo sapiens] 1888 0.0 gi|110611228 utrophin [Homo sapiens] 1483 0.0 gi|5032297 dystrophin Dp71 isoform [Homo sapiens] 1240 0.0 gi|5032299 dystrophin Dp71b isoform [Homo sapiens] 1214 0.0 gi|5032301 dystrophin Dp71a isoform [Homo sapiens] 1203 0.0 gi|5032303 dystrophin Dp71ab isoform [Homo sapiens] 1177 0.0 gi|148539558 dystrophin related protein 2 [Homo sapiens] 996 0.0 gi|5032305 dystrophin Dp40 isoform [Homo sapiens] 693 0.0 gi|42717999 dystrobrevin alpha isoform 2 [Homo sapiens] 212 2e-54 gi|42718005 dystrobrevin alpha isoform 1 [Homo sapiens] 206 8e-53 gi|42717997 dystrobrevin alpha isoform 5 [Homo sapiens] 206 8e-53 gi|42718003 dystrobrevin alpha isoform 3 [Homo sapiens] 201 5e-51 gi|42718001 dystrobrevin alpha isoform 4 [Homo sapiens] 199 1e-50 gi|11276069 dystrobrevin, beta isoform 1 [Homo sapiens] 195 3e-49 gi|37577099 dystrobrevin, beta isoform 2 [Homo sapiens] 195 3e-49 gi|37577095 dystrobrevin, beta isoform 4 [Homo sapiens] 195 3e-49 gi|15147341 dystrobrevin, beta isoform 3 [Homo sapiens] 192 1e-48 gi|37577097 dystrobrevin, beta isoform 5 [Homo sapiens] 190 8e-48 >gi|5032281 dystrophin Dp427c isoform [Homo sapiens] Length = 3677 Score = 2452 bits (6355), Expect = 0.0 Identities = 1225/1225 (100%), Positives = 1225/1225 (100%) Query: 1 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL Sbjct: 2453 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 2512 Query: 61 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK Sbjct: 2513 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 2572 Query: 121 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA Sbjct: 2573 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 2632 Query: 181 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK Sbjct: 2633 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 2692 Query: 241 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ Sbjct: 2693 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 2752 Query: 301 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW Sbjct: 2753 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 2812 Query: 361 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG Sbjct: 2813 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 2872 Query: 421 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ Sbjct: 2873 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 2932 Query: 481 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR Sbjct: 2933 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 2992 Query: 541 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP Sbjct: 2993 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 3052 Query: 601 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC Sbjct: 3053 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 3112 Query: 661 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN Sbjct: 3113 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 3172 Query: 721 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD Sbjct: 3173 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 3232 Query: 781 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR Sbjct: 3233 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 3292 Query: 841 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC Sbjct: 3293 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 3352 Query: 901 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS 960 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS Sbjct: 3353 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS 3412 Query: 961 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN 1020 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN Sbjct: 3413 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN 3472 Query: 1021 QDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLP 1080 QDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLP Sbjct: 3473 QDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLP 3532 Query: 1081 SPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQP 1140 SPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQP Sbjct: 3533 SPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQP 3592 Query: 1141 QAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVM 1200 QAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVM Sbjct: 3593 QAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVM 3652 Query: 1201 EQLNNSFPSSRGRNTPGKPMREDTM 1225 EQLNNSFPSSRGRNTPGKPMREDTM Sbjct: 3653 EQLNNSFPSSRGRNTPGKPMREDTM 3677 Score = 100 bits (249), Expect = 8e-21 Identities = 166/775 (21%), Positives = 312/775 (40%), Gaps = 89/775 (11%) Query: 20 TELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKN 79 T ++ L ++Q++ + + D ED+ + K L+Q +++ +I + + Sbjct: 1997 THVSQALLEVEQLLNAPDLCAKDFEDLFKQEESLKNIKDSLQQSSGRID-IIHSKKTAAL 2055 Query: 80 KTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEM----------LKDSTQWLEAK 129 +++ R + + + ++ QW++V + ++R+ + + +K QWL Sbjct: 2056 QSATPVERVKLQEALSQLDFQWEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIFNQWLT-- 2113 Query: 130 EEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLR 189 EAEQ L + + E+W+ Y K+L + Q QT V N ++++ Sbjct: 2114 -EAEQFLRKTQIP-ENWEHAKYK--------WYLKELQDGIGQRQTVVRTLNATGEEIIQ 2163 Query: 190 DYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAE 249 S D + ++N W+ + K++S+R+ LEE +L +F DL +F+ WL EA+ Sbjct: 2164 QSSKTDASILQEKLGSLNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEAD 2223 Query: 250 TTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGS 309 A++ + ++++L E + VK L+++ QG + L+E +L S S Sbjct: 2224 NIASIPLEPGKEQQLKEKLEQVKLLVEELPLRQG-------ILKQLNETGGPVLVSAPIS 2276 Query: 310 -DDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQE-------LLVWL 361 ++ L+ +L N +W ++ + + +EA +L L++ LL+WL Sbjct: 2277 PEEQDKLENKLKQTNLQWIKVSRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHLLLWL 2336 Query: 362 Q--LKDDELSRQAPIGGDFP------AVQ-KQNDVHRAFKR--ELKTKEPVIMSTLETVR 410 E+ Q G F AVQ KQ DV + L ++P + Sbjct: 2337 SPIRNQLEIYNQPNQEGPFDVQETEIAVQAKQPDVEEILSKGQHLYKEKPATQPVKRKLE 2396 Query: 411 IFLTEQPLEGLEKLYQEPRELPPE----------ERAQNVTRLLRKQAEEVNTEWEKLNL 460 +E + + +L QE R P+ Q VT L+ + T KL + Sbjct: 2397 DLSSE--WKAVNRLLQELRAKQPDLAPGLTTIGASPTQTVT-LVTQPVVTKETAISKLEM 2453 Query: 461 HSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKA 520 S+ ++ + + E TD L L +VIK VGDL + + + + K KA Sbjct: 2454 PSS-LMLEVPALADFNRAWTELTDWLSL---LDQVIKSQRVMVGDL--EDINEMIIKQKA 2507 Query: 521 LRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLST--LEDLNTRWKLLQVAVEDRVRQL 578 ++ + + + A+ L + T +E + +W +Q +++R +QL Sbjct: 2508 TMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQL 2567 Query: 579 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 638 +E +D S +L + + K+ + T K+TE Q DL Sbjct: 2568 NEMLKD----STQWLEAKEEAEQVLGQARAKLESW-KEGPYTVDAIQKKITETKQLAKDL 2622 Query: 639 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 698 + + + L L LL +A D H + +N I ++ Sbjct: 2623 RQWQTNV--------DVANDLALKLLRDYSADDTRKVHMITENIN-ASWRSIHKRVSERE 2673 Query: 699 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGR-----TGRIRVLSFKTGIISLCK 748 LE+ H L PL ++ L WL T T + R+L G+ L K Sbjct: 2674 AALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMK 2728 Score = 81.3 bits (199), Expect = 5e-15 Identities = 109/561 (19%), Positives = 234/561 (41%), Gaps = 59/561 (10%) Query: 22 LTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNKT 81 L W++ +D +K + +GD E + + + + + + D++ +P L + Q +KN+ Sbjct: 1052 LKKWMAEVDVFLKEEWPALGDSEILKKQLKQCRLLVSDIQTIQPSLNSVNEGGQKIKNEA 1111 Query: 82 SNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARA 141 + A + T+ ++ + QWD + + + R++ L L+ + + E + + QA Sbjct: 1112 EPEFASRLETE-LKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEE 1170 Query: 142 KLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYS--ADDTRKV 199 + T D +QK + E K+ ++ +Q + V + + ++ A + K Sbjct: 1171 EYLERDFEYKTPDELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEALKK 1230 Query: 200 HMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAE----TTANVL 255 + T N W + R++ + LEE + LEK WL E E TT N+ Sbjct: 1231 ELETLTTNYQW--LCTRLNGKCKTLEEVWACWHELLSYLEKANKWLNEVEFKLKTTENIP 1288 Query: 256 QDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLL 315 A E + E ++ LM+ +D +I +G L+ Sbjct: 1289 GGA---EEISEVLDSLENLMRHSEDNPNQIRILAQTL-------------TDGGVMDELI 1332 Query: 316 QRRLDNMNFKWSELRKKSLN----IRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQ 371 L+ N +W EL ++++ + ++++ + K LHL +QE L ++ D +L+ Sbjct: 1333 NEELETFNSRWRELHEEAVRRQKLLEQSIQSAQETEKSLHL-IQESLTFI---DKQLA-- 1386 Query: 372 APIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPREL 431 A I A Q + + I S L + I L E K + + +E Sbjct: 1387 AYIADKVDAAQMPQEAQK------------IQSDLTSHEISLEEM------KKHNQGKE- 1427 Query: 432 PPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLR 491 +R + + +K+ ++V+ ++ +L A++++++ E+ L E++ L+ K Sbjct: 1428 -AAQRVLSQIDVAQKKLQDVSMKF-RLFQKPANFEQRLQESKMILDEVKMHLPALETKSV 1485 Query: 492 QAEVIKGSWQPVGDLL--IDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQL 549 + EV++ +L + ++ +E V +I K+ + +L ++T L + Sbjct: 1486 EQEVVQSQLNHCVNLYKSLSEVKSEVEMVIKTGRQIVQ-KKQTENPKELDERVTALKLHY 1544 Query: 550 SPYNLSTLEDLNTRWKLLQVA 570 + E K L+++ Sbjct: 1545 NELGAKVTERKQQLEKCLKLS 1565 Score = 65.5 bits (158), Expect = 3e-10 Identities = 70/339 (20%), Positives = 133/339 (39%), Gaps = 22/339 (6%) Query: 3 SSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQ 62 SSLM L + A E+ WL + +++Q + D+E + + + M DL Sbjct: 324 SSLMESEVNLDRYQTALEEVLSWLLSAEDTLQAQGEISNDVEVVKDQFHTHEGYMMDLTA 383 Query: 63 RRPQLEELITAAQNL--------KNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQ 114 + ++ ++ L +T QE ++ R E ++ E Q +L Sbjct: 384 HQGRVGNILQLGSKLIGTGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLMD 443 Query: 115 L-NEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQW 173 L N+ LK+ WL EE + K+E GP ++ +++++ + K L +DL Q Sbjct: 444 LQNQKLKELNDWLTKTEERTR-------KMEEEPLGP-DLEDLKRQVQQHKVLQEDLEQE 495 Query: 174 QTNVDVANDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQ 233 Q V+ + + + T + + + W +I + +R L++ Q+ Sbjct: 496 QVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWTEDRWVLLQDILLKWQR 555 Query: 234 FPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYH 293 + F AWL+E E N + K D + +++ L+ ++E Sbjct: 556 LTEEQCLFSAWLSEKEDAVNKIHTTGFK-----DQNEMLSSLQKLAVLKADLEKKKQSMG 610 Query: 294 NLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKK 332 L Q +L +L+ + LDN W L +K Sbjct: 611 KLYSLKQDLLSTLKNKSVTQKTEAWLDNFARCWDNLVQK 649 Score = 62.0 bits (149), Expect = 3e-09 Identities = 104/571 (18%), Positives = 222/571 (38%), Gaps = 46/571 (8%) Query: 20 TELTDWLSLLDQVIKSQRVMV----GDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQ 75 TEL W++ + V++S + G+ D+ E K A ++ ++ +L++ +AQ Sbjct: 721 TELHSWITRSEAVLQSPEFAIFRKEGNFSDLKE---KVNAIEREKAEKFRKLQDASRSAQ 777 Query: 76 NLKNKTSNQEART-IITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQ 134 L + N+ I E++ ++W E + L R L E + + ++ EQ Sbjct: 778 ALVEQMVNEGVNADSIKQASEQLNSRWIEFCQLLSERLNWL-EYQNNIIAFYNQLQQLEQ 836 Query: 135 VLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYSAD 194 + A L+ P AI+ ++ K L Q ++ ++ L Sbjct: 837 MTTTAENWLKIQPTTPSEPTAIKSQLKICKDEVNRLSGLQPQIERLKIQSIALKEKGQGP 896 Query: 195 DTRKVHMITENINASWRSIHKRVSEREAALEETHRLL--QQFPLDLEKFLAWLTEAETTA 252 + ++ + V RE L+ L ++ + W+ ++ET Sbjct: 897 MFLDADFVA--FTNHFKQVFSDVQAREKELQTIFDTLPPMRYQETMSAIRTWVQQSETKL 954 Query: 253 NVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDA 312 ++ Q + ++E G + Q LQ ++ + L +++ + S+ + Sbjct: 955 SIPQLSVTDYEIMEQRLG------ELQALQSSLQEQQSGLYYLSTTVKEMSKKAP-SEIS 1007 Query: 313 VLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQA 372 Q + + +W +L + + LE ++ +++ +Q L W+ D L + Sbjct: 1008 RKYQSEFEEIEGRWKKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEW 1067 Query: 373 PIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELP 432 P GD ++KQ R +++T +P + S EG +K+ E Sbjct: 1068 PALGDSEILKKQLKQCRLLVSDIQTIQPSLNSV------------NEGGQKI---KNEAE 1112 Query: 433 PEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQ 492 PE ++ L + +E+NT+W+ + + + LE+ LQ+ E+ + Q Sbjct: 1113 PEFASR-----LETELKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQ 1167 Query: 493 A--EVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLS 550 A E ++ ++ D LQ +E++K + E + V + + + ++ Sbjct: 1168 AEEEYLERDFEYKTP---DELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVA 1224 Query: 551 PYNL-STLEDLNTRWKLLQVAVEDRVRQLHE 580 L LE L T ++ L + + + L E Sbjct: 1225 QEALKKELETLTTNYQWLCTRLNGKCKTLEE 1255 Score = 60.8 bits (146), Expect = 7e-09 Identities = 74/446 (16%), Positives = 186/446 (41%), Gaps = 40/446 (8%) Query: 58 QDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNE 117 + L + + ++E +I + + K + + + +R+ ++ ++E+ + R+QQL + Sbjct: 1502 KSLSEVKSEVEMVIKTGRQIVQKKQTENPKEL-DERVTALKLHYNELGAKVTERKQQLEK 1560 Query: 118 MLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNV 177 LK S + + + L +L + ++ K K++ + + ++ Sbjct: 1561 CLKLSRKMRKEMNVLTEWLAATDMELTKRSAVEGMPSNLDSEVAWGKATQKEIEKQKVHL 1620 Query: 178 DVANDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLD 237 ++ L +T ++ +N++W ++ R E L E + ++ F + Sbjct: 1621 KSITEVGEALKTVLGKKETLVEDKLSL-LNSNWIAVTSRAEEWLNLLLEYQKHMETFDQN 1679 Query: 238 LEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDE 297 ++ W+ +A+T L D + K++ + +K L + D++ ++++ D NL Sbjct: 1680 VDHITKWIIQADT----LLDESEKKKPQQKEDVLKRLKAELNDIRPKVDSTRDQAANLMA 1735 Query: 298 NSQKILRSLEGSDDAVLLQRRLDNMNFKWSELR------KKSLNIRSHLEASSDQWKRLH 351 N G L++ ++ +N +++ + K S+ ++ + +SD K L Sbjct: 1736 N--------RGDHCRKLVEPQISELNHRFAAISHRIKTGKASIPLKELEQFNSDIQKLLE 1787 Query: 352 LSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRI 411 E+ + LK+++ ++ N+ + +EL + + + R Sbjct: 1788 PLEAEIQQGVNLKEEDFNKD------------MNEDNEGTVKELLQRGDNLQQRITDER- 1834 Query: 412 FLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDE 471 + ++ ++L Q + R+Q RK+A E++ +W + + D + +D+ Sbjct: 1835 --KREEIKIKQQLLQTKHNALKDLRSQR-----RKKALEISHQWYQYKRQADDLLKCLDD 1887 Query: 472 TLERLQELQEATDELDLKLRQAEVIK 497 ++L L E DE +K E+ K Sbjct: 1888 IEKKLASLPEPRDERKIKEIDRELQK 1913 Score = 55.8 bits (133), Expect = 2e-07 Identities = 96/533 (18%), Positives = 216/533 (40%), Gaps = 75/533 (14%) Query: 12 LADFNRAWTELTDWL----SLLDQVIKSQRVMVGDLEDINEMI----------IKQKATM 57 L FN W EL + LL+Q I+S + L I E + I K Sbjct: 1336 LETFNSRWRELHEEAVRRQKLLEQSIQSAQETEKSLHLIQESLTFIDKQLAAYIADKVDA 1395 Query: 58 QDLEQRRPQLEELITA----AQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQ 113 + Q +++ +T+ + +K +EA +R+ +Q D Q+ LQ+ Sbjct: 1396 AQMPQEAQKIQSDLTSHEISLEEMKKHNQGKEAA-------QRVLSQIDVAQKKLQDVSM 1448 Query: 114 QLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQW 173 + + + + + +E++ +L + + L + + + +Q ++ L K L + Sbjct: 1449 KFR-LFQKPANFEQRLQESKMILDEVKMHLPALETKSVEQEVVQSQLNHCVNLYKSLSEV 1507 Query: 174 QTNVDVANDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQ 233 ++ V++ ++++ ++ +++ + + + +V+ER+ LE+ +L ++ Sbjct: 1508 KSEVEMVIKTGRQIVQKKQTENPKELDERVTALKLHYNELGAKVTERKQQLEKCLKLSRK 1567 Query: 234 FPLDLEKFLAWL--TEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDV 291 ++ WL T+ E T + E + G K K+ + + +++ T+V Sbjct: 1568 MRKEMNVLTEWLAATDMELTKRSAVEGMPSNLDSEVAWG-KATQKEIEKQKVHLKSITEV 1626 Query: 292 YHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLH 351 + L+++ G + L++ +L +N W + ++ + L + Sbjct: 1627 --------GEALKTVLGKKE-TLVEDKLSLLNSNWIAVTSRAEEWLNLLLEYQKHMETFD 1677 Query: 352 LSLQELLVWLQLKD---DELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLET 408 ++ + W+ D DE ++ P Q++ DV + K EL P + ST + Sbjct: 1678 QNVDHITKWIIQADTLLDESEKKKP--------QQKEDVLKRLKAELNDIRPKVDSTRDQ 1729 Query: 409 VRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLR--------KQAEEVNTEWEKL-- 458 + + + KL EP+ R ++ ++ K+ E+ N++ +KL Sbjct: 1730 AANLMANRG-DHCRKLV-EPQISELNHRFAAISHRIKTGKASIPLKELEQFNSDIQKLLE 1787 Query: 459 ----------NLHSADWQRKIDETLE-RLQELQEATDELDLKL---RQAEVIK 497 NL D+ + ++E E ++EL + D L ++ R+ E IK Sbjct: 1788 PLEAEIQQGVNLKEEDFNKDMNEDNEGTVKELLQRGDNLQQRITDERKREEIK 1840 Score = 47.4 bits (111), Expect = 9e-05 Identities = 68/315 (21%), Positives = 125/315 (39%), Gaps = 53/315 (16%) Query: 286 EAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS-----HL 340 E H ++H + + Q + +G + + R + + + S RS HL Sbjct: 255 EEHFQLHHQMHYSQQITVSLAQGYERTSSPKPRFKSYAYTQAAYVTTSDPTRSPFPSQHL 314 Query: 341 EASSDQ------------WKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVH 388 EA D+ R +L+E+L WL +D L Q I D V+ Q H Sbjct: 315 EAPEDKSFGSSLMESEVNLDRYQTALEEVLSWLLSAEDTLQAQGEISNDVEVVKDQFHTH 374 Query: 389 RAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQA 448 + +L + + + L+ L G KL ++ EE +++Q Sbjct: 375 EGYMMDLTAHQGRVGNILQ------LGSKLIGTGKLSED------EETE------VQEQM 416 Query: 449 EEVNTEWEKLNLHSADWQRKIDETL-----ERLQELQEATDELDLKLRQAEVIKGSWQPV 503 +N+ WE L + S + Q + L ++L+EL + + + + R+ E +P+ Sbjct: 417 NLLNSRWECLRVASMEKQSNLHRVLMDLQNQKLKELNDWLTKTEERTRKMEE-----EPL 471 Query: 504 GDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLED---- 559 G L D L+ +++ K L+ + L++ VN L + + + + LE+ Sbjct: 472 GPDLED-LKRQVQQHKVLQED---LEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKV 527 Query: 560 LNTRWKLLQVAVEDR 574 L RW + EDR Sbjct: 528 LGDRWANICRWTEDR 542 Score = 35.0 bits (79), Expect = 0.44 Identities = 41/178 (23%), Positives = 78/178 (43%), Gaps = 10/178 (5%) Query: 984 LAEMENSNGSYLNDS-ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEE 1042 L ++ + G L + ISP E E+ L Q Q + L + + I + ++ Sbjct: 2259 LKQLNETGGPVLVSAPISPEEQDKLENKLKQTNLQWIKVSRALPEKQGE----IEAQIKD 2314 Query: 1043 RGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPT----SPQSPRDAEL 1098 G+LE+ L DLEE+ +L ++ Q E P ++ T + P E+ Sbjct: 2315 LGQLEKKLEDLEEQLNHLLLWLSPIRNQLEIYNQPNQEGPFDVQETEIAVQAKQPDVEEI 2374 Query: 1099 IAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPST 1156 +++ + L + K + + LED + + ++ ++RL Q L Q + TT+ + T Sbjct: 2375 LSKGQHLYKEKPATQPVKRKLEDLSSEWKA-VNRLLQELRAKQPDLAPGLTTIGASPT 2431 >gi|5032291 dystrophin Dp260-2 isoform [Homo sapiens] Length = 2341 Score = 2452 bits (6355), Expect = 0.0 Identities = 1225/1225 (100%), Positives = 1225/1225 (100%) Query: 1 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL Sbjct: 1117 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 1176 Query: 61 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK Sbjct: 1177 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 1236 Query: 121 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA Sbjct: 1237 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 1296 Query: 181 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK Sbjct: 1297 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 1356 Query: 241 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ Sbjct: 1357 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 1416 Query: 301 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW Sbjct: 1417 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 1476 Query: 361 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG Sbjct: 1477 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 1536 Query: 421 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ Sbjct: 1537 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 1596 Query: 481 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR Sbjct: 1597 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 1656 Query: 541 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP Sbjct: 1657 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 1716 Query: 601 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC Sbjct: 1717 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 1776 Query: 661 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN Sbjct: 1777 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 1836 Query: 721 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD Sbjct: 1837 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 1896 Query: 781 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR Sbjct: 1897 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 1956 Query: 841 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC Sbjct: 1957 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 2016 Query: 901 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS 960 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS Sbjct: 2017 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS 2076 Query: 961 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN 1020 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN Sbjct: 2077 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN 2136 Query: 1021 QDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLP 1080 QDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLP Sbjct: 2137 QDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLP 2196 Query: 1081 SPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQP 1140 SPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQP Sbjct: 2197 SPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQP 2256 Query: 1141 QAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVM 1200 QAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVM Sbjct: 2257 QAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVM 2316 Query: 1201 EQLNNSFPSSRGRNTPGKPMREDTM 1225 EQLNNSFPSSRGRNTPGKPMREDTM Sbjct: 2317 EQLNNSFPSSRGRNTPGKPMREDTM 2341 Score = 100 bits (249), Expect = 8e-21 Identities = 166/775 (21%), Positives = 312/775 (40%), Gaps = 89/775 (11%) Query: 20 TELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKN 79 T ++ L ++Q++ + + D ED+ + K L+Q +++ +I + + Sbjct: 661 THVSQALLEVEQLLNAPDLCAKDFEDLFKQEESLKNIKDSLQQSSGRID-IIHSKKTAAL 719 Query: 80 KTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEM----------LKDSTQWLEAK 129 +++ R + + + ++ QW++V + ++R+ + + +K QWL Sbjct: 720 QSATPVERVKLQEALSQLDFQWEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIFNQWLT-- 777 Query: 130 EEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLR 189 EAEQ L + + E+W+ Y K+L + Q QT V N ++++ Sbjct: 778 -EAEQFLRKTQIP-ENWEHAKYK--------WYLKELQDGIGQRQTVVRTLNATGEEIIQ 827 Query: 190 DYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAE 249 S D + ++N W+ + K++S+R+ LEE +L +F DL +F+ WL EA+ Sbjct: 828 QSSKTDASILQEKLGSLNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEAD 887 Query: 250 TTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGS 309 A++ + ++++L E + VK L+++ QG + L+E +L S S Sbjct: 888 NIASIPLEPGKEQQLKEKLEQVKLLVEELPLRQG-------ILKQLNETGGPVLVSAPIS 940 Query: 310 -DDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQE-------LLVWL 361 ++ L+ +L N +W ++ + + +EA +L L++ LL+WL Sbjct: 941 PEEQDKLENKLKQTNLQWIKVSRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHLLLWL 1000 Query: 362 Q--LKDDELSRQAPIGGDFP------AVQ-KQNDVHRAFKR--ELKTKEPVIMSTLETVR 410 E+ Q G F AVQ KQ DV + L ++P + Sbjct: 1001 SPIRNQLEIYNQPNQEGPFDVQETEIAVQAKQPDVEEILSKGQHLYKEKPATQPVKRKLE 1060 Query: 411 IFLTEQPLEGLEKLYQEPRELPPE----------ERAQNVTRLLRKQAEEVNTEWEKLNL 460 +E + + +L QE R P+ Q VT L+ + T KL + Sbjct: 1061 DLSSE--WKAVNRLLQELRAKQPDLAPGLTTIGASPTQTVT-LVTQPVVTKETAISKLEM 1117 Query: 461 HSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKA 520 S+ ++ + + E TD L L +VIK VGDL + + + + K KA Sbjct: 1118 PSS-LMLEVPALADFNRAWTELTDWLSL---LDQVIKSQRVMVGDL--EDINEMIIKQKA 1171 Query: 521 LRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLST--LEDLNTRWKLLQVAVEDRVRQL 578 ++ + + + A+ L + T +E + +W +Q +++R +QL Sbjct: 1172 TMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQL 1231 Query: 579 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 638 +E +D S +L + + K+ + T K+TE Q DL Sbjct: 1232 NEMLKD----STQWLEAKEEAEQVLGQARAKLESW-KEGPYTVDAIQKKITETKQLAKDL 1286 Query: 639 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 698 + + + L L LL +A D H + +N I ++ Sbjct: 1287 RQWQTNV--------DVANDLALKLLRDYSADDTRKVHMITENIN-ASWRSIHKRVSERE 1337 Query: 699 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGR-----TGRIRVLSFKTGIISLCK 748 LE+ H L PL ++ L WL T T + R+L G+ L K Sbjct: 1338 AALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMK 1392 Score = 73.6 bits (179), Expect = 1e-12 Identities = 128/599 (21%), Positives = 244/599 (40%), Gaps = 58/599 (9%) Query: 22 LTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNKT 81 LT+WL+ D + + + G +++ + KAT +++E+++ L+ + + LK Sbjct: 239 LTEWLAATDMELTKRSAVEGMPSNLDSEVAWGKATQKEIEKQKVHLKSITEVGEALKTVL 298 Query: 82 SNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARA 141 +E T++ D++ + + W V + L E K + + + + + QA Sbjct: 299 GKKE--TLVEDKLSLLNSNWIAVTSRAEEWLNLLLEYQKHMETFDQNVDHITKWIIQADT 356 Query: 142 KL-ESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYSADDTRKVH 200 L ES K+ P Q+K K+L +L + VD D A L+ + + V Sbjct: 357 LLDESEKKKP------QQKEDVLKRLKAELNDIRPKVDSTRDQAANLMANRGDHCRKLVE 410 Query: 201 MITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAETTANV-LQDAT 259 +N + +I R+ +A++ + L+QF D++K L L EAE V L++ Sbjct: 411 PQISELNHRFAAISHRIKTGKASI--PLKELEQFNSDIQKLLEPL-EAEIQQGVNLKEED 467 Query: 260 RKERLLEDSKG-VKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRR 318 + + ED++G VKEL+++ +LQ I DE ++ ++ + LLQ + Sbjct: 468 FNKDMNEDNEGTVKELLQRGDNLQQRI---------TDERKREEIKIKQ-----QLLQTK 513 Query: 319 LDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDF 378 + + S+ RKK+L I S QW + +LL L + +L+ P D Sbjct: 514 HNALKDLRSQRRKKALEI-------SHQWYQYKRQADDLLKCLDDIEKKLA-SLPEPRDE 565 Query: 379 PAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQ 438 +++ + + K EL E E L K ++E + R Sbjct: 566 RKIKEIDRELQKKKEELNAVRRQAEGLSEDGAAMAVEPTQIQLSKRWREIESKFAQFRRL 625 Query: 439 NVTRL--LRKQAEEVNTEWEKLNLH--SADWQRKIDETLERLQELQEATDELDLKLRQAE 494 N ++ +R++ V TE L + + + +I + L E+++ + DL + E Sbjct: 626 NFAQIHTVREETMMVMTEDMPLEISYVPSTYLTEITHVSQALLEVEQLLNAPDLCAKDFE 685 Query: 495 VIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVN--DLARQLTTLGIQLSPY 552 + + + ++ DSLQ ++ + + ++ + V L L+ L Q Sbjct: 686 DLFKQEESLKNIK-DSLQQSSGRIDIIHSKKTAALQSATPVERVKLQEALSQLDFQ---- 740 Query: 553 NLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRD-------FGPASQHFLSTSVQGPWERA 604 E +N +K Q + V + H D A Q T + WE A Sbjct: 741 ----WEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIFNQWLTEAEQFLRKTQIPENWEHA 795 Score = 52.4 bits (124), Expect = 3e-06 Identities = 87/493 (17%), Positives = 199/493 (40%), Gaps = 64/493 (12%) Query: 34 KSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDR 93 K + D D +M + + DL LEE+ K +EA Sbjct: 47 KQLAAYIADKVDAAQMPQEAQKIQSDLTSHEISLEEM-------KKHNQGKEAA------ 93 Query: 94 IERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTV 153 +R+ +Q D Q+ LQ+ + + + + + +E++ +L + + L + + Sbjct: 94 -QRVLSQIDVAQKKLQDVSMKFR-LFQKPANFEQRLQESKMILDEVKMHLPALETKSVEQ 151 Query: 154 DAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYSADDTRKVHMITENINASWRSI 213 + +Q ++ L K L + ++ V++ ++++ ++ +++ + + + Sbjct: 152 EVVQSQLNHCVNLYKSLSEVKSEVEMVIKTGRQIVQKKQTENPKELDERVTALKLHYNEL 211 Query: 214 HKRVSEREAALEETHRLLQQFPLDLEKFLAWL--TEAETTANVLQDATRKERLLEDSKGV 271 +V+ER+ LE+ +L ++ ++ WL T+ E T + E + G Sbjct: 212 GAKVTERKQQLEKCLKLSRKMRKEMNVLTEWLAATDMELTKRSAVEGMPSNLDSEVAWG- 270 Query: 272 KELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRK 331 K K+ + + +++ T+V + L+++ G + L++ +L +N W + Sbjct: 271 KATQKEIEKQKVHLKSITEV--------GEALKTVLGKKE-TLVEDKLSLLNSNWIAVTS 321 Query: 332 KSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKD---DELSRQAPIGGDFPAVQKQNDVH 388 ++ + L + ++ + W+ D DE ++ P Q++ DV Sbjct: 322 RAEEWLNLLLEYQKHMETFDQNVDHITKWIIQADTLLDESEKKKP--------QQKEDVL 373 Query: 389 RAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLR--- 445 + K EL P + ST + + + + KL EP+ R ++ ++ Sbjct: 374 KRLKAELNDIRPKVDSTRDQAANLMANRG-DHCRKLV-EPQISELNHRFAAISHRIKTGK 431 Query: 446 -----KQAEEVNTEWEKL------------NLHSADWQRKIDETLE-RLQELQEATDELD 487 K+ E+ N++ +KL NL D+ + ++E E ++EL + D L Sbjct: 432 ASIPLKELEQFNSDIQKLLEPLEAEIQQGVNLKEEDFNKDMNEDNEGTVKELLQRGDNLQ 491 Query: 488 LKL---RQAEVIK 497 ++ R+ E IK Sbjct: 492 QRITDERKREEIK 504 Score = 35.0 bits (79), Expect = 0.44 Identities = 41/178 (23%), Positives = 78/178 (43%), Gaps = 10/178 (5%) Query: 984 LAEMENSNGSYLNDS-ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEE 1042 L ++ + G L + ISP E E+ L Q Q + L + + I + ++ Sbjct: 923 LKQLNETGGPVLVSAPISPEEQDKLENKLKQTNLQWIKVSRALPEKQGE----IEAQIKD 978 Query: 1043 RGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPT----SPQSPRDAEL 1098 G+LE+ L DLEE+ +L ++ Q E P ++ T + P E+ Sbjct: 979 LGQLEKKLEDLEEQLNHLLLWLSPIRNQLEIYNQPNQEGPFDVQETEIAVQAKQPDVEEI 1038 Query: 1099 IAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPST 1156 +++ + L + K + + LED + + ++ ++RL Q L Q + TT+ + T Sbjct: 1039 LSKGQHLYKEKPATQPVKRKLEDLSSEWKA-VNRLLQELRAKQPDLAPGLTTIGASPT 1095 >gi|150036268 dystrophin Dp260-1 isoform [Homo sapiens] Length = 2344 Score = 2452 bits (6355), Expect = 0.0 Identities = 1225/1225 (100%), Positives = 1225/1225 (100%) Query: 1 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL Sbjct: 1120 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 1179 Query: 61 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK Sbjct: 1180 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 1239 Query: 121 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA Sbjct: 1240 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 1299 Query: 181 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK Sbjct: 1300 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 1359 Query: 241 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ Sbjct: 1360 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 1419 Query: 301 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW Sbjct: 1420 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 1479 Query: 361 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG Sbjct: 1480 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 1539 Query: 421 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ Sbjct: 1540 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 1599 Query: 481 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR Sbjct: 1600 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 1659 Query: 541 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP Sbjct: 1660 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 1719 Query: 601 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC Sbjct: 1720 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 1779 Query: 661 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN Sbjct: 1780 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 1839 Query: 721 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD Sbjct: 1840 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 1899 Query: 781 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR Sbjct: 1900 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 1959 Query: 841 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC Sbjct: 1960 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 2019 Query: 901 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS 960 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS Sbjct: 2020 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS 2079 Query: 961 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN 1020 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN Sbjct: 2080 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN 2139 Query: 1021 QDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLP 1080 QDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLP Sbjct: 2140 QDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLP 2199 Query: 1081 SPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQP 1140 SPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQP Sbjct: 2200 SPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQP 2259 Query: 1141 QAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVM 1200 QAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVM Sbjct: 2260 QAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVM 2319 Query: 1201 EQLNNSFPSSRGRNTPGKPMREDTM 1225 EQLNNSFPSSRGRNTPGKPMREDTM Sbjct: 2320 EQLNNSFPSSRGRNTPGKPMREDTM 2344 Score = 100 bits (249), Expect = 8e-21 Identities = 166/775 (21%), Positives = 312/775 (40%), Gaps = 89/775 (11%) Query: 20 TELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKN 79 T ++ L ++Q++ + + D ED+ + K L+Q +++ +I + + Sbjct: 664 THVSQALLEVEQLLNAPDLCAKDFEDLFKQEESLKNIKDSLQQSSGRID-IIHSKKTAAL 722 Query: 80 KTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEM----------LKDSTQWLEAK 129 +++ R + + + ++ QW++V + ++R+ + + +K QWL Sbjct: 723 QSATPVERVKLQEALSQLDFQWEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIFNQWLT-- 780 Query: 130 EEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLR 189 EAEQ L + + E+W+ Y K+L + Q QT V N ++++ Sbjct: 781 -EAEQFLRKTQIP-ENWEHAKYK--------WYLKELQDGIGQRQTVVRTLNATGEEIIQ 830 Query: 190 DYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAE 249 S D + ++N W+ + K++S+R+ LEE +L +F DL +F+ WL EA+ Sbjct: 831 QSSKTDASILQEKLGSLNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEAD 890 Query: 250 TTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGS 309 A++ + ++++L E + VK L+++ QG + L+E +L S S Sbjct: 891 NIASIPLEPGKEQQLKEKLEQVKLLVEELPLRQG-------ILKQLNETGGPVLVSAPIS 943 Query: 310 -DDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQE-------LLVWL 361 ++ L+ +L N +W ++ + + +EA +L L++ LL+WL Sbjct: 944 PEEQDKLENKLKQTNLQWIKVSRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHLLLWL 1003 Query: 362 Q--LKDDELSRQAPIGGDFP------AVQ-KQNDVHRAFKR--ELKTKEPVIMSTLETVR 410 E+ Q G F AVQ KQ DV + L ++P + Sbjct: 1004 SPIRNQLEIYNQPNQEGPFDVQETEIAVQAKQPDVEEILSKGQHLYKEKPATQPVKRKLE 1063 Query: 411 IFLTEQPLEGLEKLYQEPRELPPE----------ERAQNVTRLLRKQAEEVNTEWEKLNL 460 +E + + +L QE R P+ Q VT L+ + T KL + Sbjct: 1064 DLSSE--WKAVNRLLQELRAKQPDLAPGLTTIGASPTQTVT-LVTQPVVTKETAISKLEM 1120 Query: 461 HSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKA 520 S+ ++ + + E TD L L +VIK VGDL + + + + K KA Sbjct: 1121 PSS-LMLEVPALADFNRAWTELTDWLSL---LDQVIKSQRVMVGDL--EDINEMIIKQKA 1174 Query: 521 LRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLST--LEDLNTRWKLLQVAVEDRVRQL 578 ++ + + + A+ L + T +E + +W +Q +++R +QL Sbjct: 1175 TMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQL 1234 Query: 579 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 638 +E +D S +L + + K+ + T K+TE Q DL Sbjct: 1235 NEMLKD----STQWLEAKEEAEQVLGQARAKLESW-KEGPYTVDAIQKKITETKQLAKDL 1289 Query: 639 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 698 + + + L L LL +A D H + +N I ++ Sbjct: 1290 RQWQTNV--------DVANDLALKLLRDYSADDTRKVHMITENIN-ASWRSIHKRVSERE 1340 Query: 699 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGR-----TGRIRVLSFKTGIISLCK 748 LE+ H L PL ++ L WL T T + R+L G+ L K Sbjct: 1341 AALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMK 1395 Score = 73.6 bits (179), Expect = 1e-12 Identities = 128/599 (21%), Positives = 244/599 (40%), Gaps = 58/599 (9%) Query: 22 LTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNKT 81 LT+WL+ D + + + G +++ + KAT +++E+++ L+ + + LK Sbjct: 242 LTEWLAATDMELTKRSAVEGMPSNLDSEVAWGKATQKEIEKQKVHLKSITEVGEALKTVL 301 Query: 82 SNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARA 141 +E T++ D++ + + W V + L E K + + + + + QA Sbjct: 302 GKKE--TLVEDKLSLLNSNWIAVTSRAEEWLNLLLEYQKHMETFDQNVDHITKWIIQADT 359 Query: 142 KL-ESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYSADDTRKVH 200 L ES K+ P Q+K K+L +L + VD D A L+ + + V Sbjct: 360 LLDESEKKKP------QQKEDVLKRLKAELNDIRPKVDSTRDQAANLMANRGDHCRKLVE 413 Query: 201 MITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAETTANV-LQDAT 259 +N + +I R+ +A++ + L+QF D++K L L EAE V L++ Sbjct: 414 PQISELNHRFAAISHRIKTGKASI--PLKELEQFNSDIQKLLEPL-EAEIQQGVNLKEED 470 Query: 260 RKERLLEDSKG-VKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRR 318 + + ED++G VKEL+++ +LQ I DE ++ ++ + LLQ + Sbjct: 471 FNKDMNEDNEGTVKELLQRGDNLQQRI---------TDERKREEIKIKQ-----QLLQTK 516 Query: 319 LDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDF 378 + + S+ RKK+L I S QW + +LL L + +L+ P D Sbjct: 517 HNALKDLRSQRRKKALEI-------SHQWYQYKRQADDLLKCLDDIEKKLA-SLPEPRDE 568 Query: 379 PAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQ 438 +++ + + K EL E E L K ++E + R Sbjct: 569 RKIKEIDRELQKKKEELNAVRRQAEGLSEDGAAMAVEPTQIQLSKRWREIESKFAQFRRL 628 Query: 439 NVTRL--LRKQAEEVNTEWEKLNLH--SADWQRKIDETLERLQELQEATDELDLKLRQAE 494 N ++ +R++ V TE L + + + +I + L E+++ + DL + E Sbjct: 629 NFAQIHTVREETMMVMTEDMPLEISYVPSTYLTEITHVSQALLEVEQLLNAPDLCAKDFE 688 Query: 495 VIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVN--DLARQLTTLGIQLSPY 552 + + + ++ DSLQ ++ + + ++ + V L L+ L Q Sbjct: 689 DLFKQEESLKNIK-DSLQQSSGRIDIIHSKKTAALQSATPVERVKLQEALSQLDFQ---- 743 Query: 553 NLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRD-------FGPASQHFLSTSVQGPWERA 604 E +N +K Q + V + H D A Q T + WE A Sbjct: 744 ----WEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIFNQWLTEAEQFLRKTQIPENWEHA 798 Score = 52.4 bits (124), Expect = 3e-06 Identities = 87/493 (17%), Positives = 199/493 (40%), Gaps = 64/493 (12%) Query: 34 KSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDR 93 K + D D +M + + DL LEE+ K +EA Sbjct: 50 KQLAAYIADKVDAAQMPQEAQKIQSDLTSHEISLEEM-------KKHNQGKEAA------ 96 Query: 94 IERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTV 153 +R+ +Q D Q+ LQ+ + + + + + +E++ +L + + L + + Sbjct: 97 -QRVLSQIDVAQKKLQDVSMKFR-LFQKPANFEQRLQESKMILDEVKMHLPALETKSVEQ 154 Query: 154 DAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYSADDTRKVHMITENINASWRSI 213 + +Q ++ L K L + ++ V++ ++++ ++ +++ + + + Sbjct: 155 EVVQSQLNHCVNLYKSLSEVKSEVEMVIKTGRQIVQKKQTENPKELDERVTALKLHYNEL 214 Query: 214 HKRVSEREAALEETHRLLQQFPLDLEKFLAWL--TEAETTANVLQDATRKERLLEDSKGV 271 +V+ER+ LE+ +L ++ ++ WL T+ E T + E + G Sbjct: 215 GAKVTERKQQLEKCLKLSRKMRKEMNVLTEWLAATDMELTKRSAVEGMPSNLDSEVAWG- 273 Query: 272 KELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRK 331 K K+ + + +++ T+V + L+++ G + L++ +L +N W + Sbjct: 274 KATQKEIEKQKVHLKSITEV--------GEALKTVLGKKE-TLVEDKLSLLNSNWIAVTS 324 Query: 332 KSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKD---DELSRQAPIGGDFPAVQKQNDVH 388 ++ + L + ++ + W+ D DE ++ P Q++ DV Sbjct: 325 RAEEWLNLLLEYQKHMETFDQNVDHITKWIIQADTLLDESEKKKP--------QQKEDVL 376 Query: 389 RAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLR--- 445 + K EL P + ST + + + + KL EP+ R ++ ++ Sbjct: 377 KRLKAELNDIRPKVDSTRDQAANLMANRG-DHCRKLV-EPQISELNHRFAAISHRIKTGK 434 Query: 446 -----KQAEEVNTEWEKL------------NLHSADWQRKIDETLE-RLQELQEATDELD 487 K+ E+ N++ +KL NL D+ + ++E E ++EL + D L Sbjct: 435 ASIPLKELEQFNSDIQKLLEPLEAEIQQGVNLKEEDFNKDMNEDNEGTVKELLQRGDNLQ 494 Query: 488 LKL---RQAEVIK 497 ++ R+ E IK Sbjct: 495 QRITDERKREEIK 507 Score = 35.0 bits (79), Expect = 0.44 Identities = 41/178 (23%), Positives = 78/178 (43%), Gaps = 10/178 (5%) Query: 984 LAEMENSNGSYLNDS-ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEE 1042 L ++ + G L + ISP E E+ L Q Q + L + + I + ++ Sbjct: 926 LKQLNETGGPVLVSAPISPEEQDKLENKLKQTNLQWIKVSRALPEKQGE----IEAQIKD 981 Query: 1043 RGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPT----SPQSPRDAEL 1098 G+LE+ L DLEE+ +L ++ Q E P ++ T + P E+ Sbjct: 982 LGQLEKKLEDLEEQLNHLLLWLSPIRNQLEIYNQPNQEGPFDVQETEIAVQAKQPDVEEI 1041 Query: 1099 IAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPST 1156 +++ + L + K + + LED + + ++ ++RL Q L Q + TT+ + T Sbjct: 1042 LSKGQHLYKEKPATQPVKRKLEDLSSEWKA-VNRLLQELRAKQPDLAPGLTTIGASPT 1098 >gi|5032315 dystrophin Dp427p2 isoform [Homo sapiens] Length = 3562 Score = 2452 bits (6355), Expect = 0.0 Identities = 1225/1225 (100%), Positives = 1225/1225 (100%) Query: 1 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL Sbjct: 2338 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 2397 Query: 61 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK Sbjct: 2398 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 2457 Query: 121 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA Sbjct: 2458 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 2517 Query: 181 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK Sbjct: 2518 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 2577 Query: 241 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ Sbjct: 2578 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 2637 Query: 301 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW Sbjct: 2638 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 2697 Query: 361 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG Sbjct: 2698 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 2757 Query: 421 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ Sbjct: 2758 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 2817 Query: 481 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR Sbjct: 2818 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 2877 Query: 541 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP Sbjct: 2878 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 2937 Query: 601 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC Sbjct: 2938 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 2997 Query: 661 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN Sbjct: 2998 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 3057 Query: 721 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD Sbjct: 3058 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 3117 Query: 781 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR Sbjct: 3118 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 3177 Query: 841 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC Sbjct: 3178 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 3237 Query: 901 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS 960 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS Sbjct: 3238 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS 3297 Query: 961 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN 1020 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN Sbjct: 3298 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN 3357 Query: 1021 QDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLP 1080 QDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLP Sbjct: 3358 QDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLP 3417 Query: 1081 SPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQP 1140 SPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQP Sbjct: 3418 SPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQP 3477 Query: 1141 QAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVM 1200 QAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVM Sbjct: 3478 QAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVM 3537 Query: 1201 EQLNNSFPSSRGRNTPGKPMREDTM 1225 EQLNNSFPSSRGRNTPGKPMREDTM Sbjct: 3538 EQLNNSFPSSRGRNTPGKPMREDTM 3562 Score = 100 bits (249), Expect = 8e-21 Identities = 166/775 (21%), Positives = 312/775 (40%), Gaps = 89/775 (11%) Query: 20 TELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKN 79 T ++ L ++Q++ + + D ED+ + K L+Q +++ +I + + Sbjct: 1882 THVSQALLEVEQLLNAPDLCAKDFEDLFKQEESLKNIKDSLQQSSGRID-IIHSKKTAAL 1940 Query: 80 KTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEM----------LKDSTQWLEAK 129 +++ R + + + ++ QW++V + ++R+ + + +K QWL Sbjct: 1941 QSATPVERVKLQEALSQLDFQWEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIFNQWLT-- 1998 Query: 130 EEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLR 189 EAEQ L + + E+W+ Y K+L + Q QT V N ++++ Sbjct: 1999 -EAEQFLRKTQIP-ENWEHAKYK--------WYLKELQDGIGQRQTVVRTLNATGEEIIQ 2048 Query: 190 DYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAE 249 S D + ++N W+ + K++S+R+ LEE +L +F DL +F+ WL EA+ Sbjct: 2049 QSSKTDASILQEKLGSLNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEAD 2108 Query: 250 TTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGS 309 A++ + ++++L E + VK L+++ QG + L+E +L S S Sbjct: 2109 NIASIPLEPGKEQQLKEKLEQVKLLVEELPLRQG-------ILKQLNETGGPVLVSAPIS 2161 Query: 310 -DDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQE-------LLVWL 361 ++ L+ +L N +W ++ + + +EA +L L++ LL+WL Sbjct: 2162 PEEQDKLENKLKQTNLQWIKVSRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHLLLWL 2221 Query: 362 Q--LKDDELSRQAPIGGDFP------AVQ-KQNDVHRAFKR--ELKTKEPVIMSTLETVR 410 E+ Q G F AVQ KQ DV + L ++P + Sbjct: 2222 SPIRNQLEIYNQPNQEGPFDVQETEIAVQAKQPDVEEILSKGQHLYKEKPATQPVKRKLE 2281 Query: 411 IFLTEQPLEGLEKLYQEPRELPPE----------ERAQNVTRLLRKQAEEVNTEWEKLNL 460 +E + + +L QE R P+ Q VT L+ + T KL + Sbjct: 2282 DLSSE--WKAVNRLLQELRAKQPDLAPGLTTIGASPTQTVT-LVTQPVVTKETAISKLEM 2338 Query: 461 HSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKA 520 S+ ++ + + E TD L L +VIK VGDL + + + + K KA Sbjct: 2339 PSS-LMLEVPALADFNRAWTELTDWLSL---LDQVIKSQRVMVGDL--EDINEMIIKQKA 2392 Query: 521 LRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLST--LEDLNTRWKLLQVAVEDRVRQL 578 ++ + + + A+ L + T +E + +W +Q +++R +QL Sbjct: 2393 TMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQL 2452 Query: 579 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 638 +E +D S +L + + K+ + T K+TE Q DL Sbjct: 2453 NEMLKD----STQWLEAKEEAEQVLGQARAKLESW-KEGPYTVDAIQKKITETKQLAKDL 2507 Query: 639 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 698 + + + L L LL +A D H + +N I ++ Sbjct: 2508 RQWQTNV--------DVANDLALKLLRDYSADDTRKVHMITENIN-ASWRSIHKRVSERE 2558 Query: 699 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGR-----TGRIRVLSFKTGIISLCK 748 LE+ H L PL ++ L WL T T + R+L G+ L K Sbjct: 2559 AALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMK 2613 Score = 81.3 bits (199), Expect = 5e-15 Identities = 109/561 (19%), Positives = 234/561 (41%), Gaps = 59/561 (10%) Query: 22 LTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNKT 81 L W++ +D +K + +GD E + + + + + + D++ +P L + Q +KN+ Sbjct: 937 LKKWMAEVDVFLKEEWPALGDSEILKKQLKQCRLLVSDIQTIQPSLNSVNEGGQKIKNEA 996 Query: 82 SNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARA 141 + A + T+ ++ + QWD + + + R++ L L+ + + E + + QA Sbjct: 997 EPEFASRLETE-LKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEE 1055 Query: 142 KLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYS--ADDTRKV 199 + T D +QK + E K+ ++ +Q + V + + ++ A + K Sbjct: 1056 EYLERDFEYKTPDELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEALKK 1115 Query: 200 HMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAE----TTANVL 255 + T N W + R++ + LEE + LEK WL E E TT N+ Sbjct: 1116 ELETLTTNYQW--LCTRLNGKCKTLEEVWACWHELLSYLEKANKWLNEVEFKLKTTENIP 1173 Query: 256 QDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLL 315 A E + E ++ LM+ +D +I +G L+ Sbjct: 1174 GGA---EEISEVLDSLENLMRHSEDNPNQIRILAQTL-------------TDGGVMDELI 1217 Query: 316 QRRLDNMNFKWSELRKKSLN----IRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQ 371 L+ N +W EL ++++ + ++++ + K LHL +QE L ++ D +L+ Sbjct: 1218 NEELETFNSRWRELHEEAVRRQKLLEQSIQSAQETEKSLHL-IQESLTFI---DKQLA-- 1271 Query: 372 APIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPREL 431 A I A Q + + I S L + I L E K + + +E Sbjct: 1272 AYIADKVDAAQMPQEAQK------------IQSDLTSHEISLEEM------KKHNQGKE- 1312 Query: 432 PPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLR 491 +R + + +K+ ++V+ ++ +L A++++++ E+ L E++ L+ K Sbjct: 1313 -AAQRVLSQIDVAQKKLQDVSMKF-RLFQKPANFEQRLQESKMILDEVKMHLPALETKSV 1370 Query: 492 QAEVIKGSWQPVGDLL--IDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQL 549 + EV++ +L + ++ +E V +I K+ + +L ++T L + Sbjct: 1371 EQEVVQSQLNHCVNLYKSLSEVKSEVEMVIKTGRQIVQ-KKQTENPKELDERVTALKLHY 1429 Query: 550 SPYNLSTLEDLNTRWKLLQVA 570 + E K L+++ Sbjct: 1430 NELGAKVTERKQQLEKCLKLS 1450 Score = 65.5 bits (158), Expect = 3e-10 Identities = 70/339 (20%), Positives = 133/339 (39%), Gaps = 22/339 (6%) Query: 3 SSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQ 62 SSLM L + A E+ WL + +++Q + D+E + + + M DL Sbjct: 209 SSLMESEVNLDRYQTALEEVLSWLLSAEDTLQAQGEISNDVEVVKDQFHTHEGYMMDLTA 268 Query: 63 RRPQLEELITAAQNL--------KNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQ 114 + ++ ++ L +T QE ++ R E ++ E Q +L Sbjct: 269 HQGRVGNILQLGSKLIGTGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLMD 328 Query: 115 L-NEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQW 173 L N+ LK+ WL EE + K+E GP ++ +++++ + K L +DL Q Sbjct: 329 LQNQKLKELNDWLTKTEERTR-------KMEEEPLGP-DLEDLKRQVQQHKVLQEDLEQE 380 Query: 174 QTNVDVANDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQ 233 Q V+ + + + T + + + W +I + +R L++ Q+ Sbjct: 381 QVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWTEDRWVLLQDILLKWQR 440 Query: 234 FPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYH 293 + F AWL+E E N + K D + +++ L+ ++E Sbjct: 441 LTEEQCLFSAWLSEKEDAVNKIHTTGFK-----DQNEMLSSLQKLAVLKADLEKKKQSMG 495 Query: 294 NLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKK 332 L Q +L +L+ + LDN W L +K Sbjct: 496 KLYSLKQDLLSTLKNKSVTQKTEAWLDNFARCWDNLVQK 534 Score = 62.0 bits (149), Expect = 3e-09 Identities = 104/571 (18%), Positives = 222/571 (38%), Gaps = 46/571 (8%) Query: 20 TELTDWLSLLDQVIKSQRVMV----GDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQ 75 TEL W++ + V++S + G+ D+ E K A ++ ++ +L++ +AQ Sbjct: 606 TELHSWITRSEAVLQSPEFAIFRKEGNFSDLKE---KVNAIEREKAEKFRKLQDASRSAQ 662 Query: 76 NLKNKTSNQEART-IITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQ 134 L + N+ I E++ ++W E + L R L E + + ++ EQ Sbjct: 663 ALVEQMVNEGVNADSIKQASEQLNSRWIEFCQLLSERLNWL-EYQNNIIAFYNQLQQLEQ 721 Query: 135 VLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYSAD 194 + A L+ P AI+ ++ K L Q ++ ++ L Sbjct: 722 MTTTAENWLKIQPTTPSEPTAIKSQLKICKDEVNRLSGLQPQIERLKIQSIALKEKGQGP 781 Query: 195 DTRKVHMITENINASWRSIHKRVSEREAALEETHRLL--QQFPLDLEKFLAWLTEAETTA 252 + ++ + V RE L+ L ++ + W+ ++ET Sbjct: 782 MFLDADFVA--FTNHFKQVFSDVQAREKELQTIFDTLPPMRYQETMSAIRTWVQQSETKL 839 Query: 253 NVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDA 312 ++ Q + ++E G + Q LQ ++ + L +++ + S+ + Sbjct: 840 SIPQLSVTDYEIMEQRLG------ELQALQSSLQEQQSGLYYLSTTVKEMSKKAP-SEIS 892 Query: 313 VLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQA 372 Q + + +W +L + + LE ++ +++ +Q L W+ D L + Sbjct: 893 RKYQSEFEEIEGRWKKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEW 952 Query: 373 PIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELP 432 P GD ++KQ R +++T +P + S EG +K+ E Sbjct: 953 PALGDSEILKKQLKQCRLLVSDIQTIQPSLNSV------------NEGGQKI---KNEAE 997 Query: 433 PEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQ 492 PE ++ L + +E+NT+W+ + + + LE+ LQ+ E+ + Q Sbjct: 998 PEFASR-----LETELKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQ 1052 Query: 493 A--EVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLS 550 A E ++ ++ D LQ +E++K + E + V + + + ++ Sbjct: 1053 AEEEYLERDFEYKTP---DELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVA 1109 Query: 551 PYNL-STLEDLNTRWKLLQVAVEDRVRQLHE 580 L LE L T ++ L + + + L E Sbjct: 1110 QEALKKELETLTTNYQWLCTRLNGKCKTLEE 1140 Score = 60.8 bits (146), Expect = 7e-09 Identities = 74/446 (16%), Positives = 186/446 (41%), Gaps = 40/446 (8%) Query: 58 QDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNE 117 + L + + ++E +I + + K + + + +R+ ++ ++E+ + R+QQL + Sbjct: 1387 KSLSEVKSEVEMVIKTGRQIVQKKQTENPKEL-DERVTALKLHYNELGAKVTERKQQLEK 1445 Query: 118 MLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNV 177 LK S + + + L +L + ++ K K++ + + ++ Sbjct: 1446 CLKLSRKMRKEMNVLTEWLAATDMELTKRSAVEGMPSNLDSEVAWGKATQKEIEKQKVHL 1505 Query: 178 DVANDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLD 237 ++ L +T ++ +N++W ++ R E L E + ++ F + Sbjct: 1506 KSITEVGEALKTVLGKKETLVEDKLSL-LNSNWIAVTSRAEEWLNLLLEYQKHMETFDQN 1564 Query: 238 LEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDE 297 ++ W+ +A+T L D + K++ + +K L + D++ ++++ D NL Sbjct: 1565 VDHITKWIIQADT----LLDESEKKKPQQKEDVLKRLKAELNDIRPKVDSTRDQAANLMA 1620 Query: 298 NSQKILRSLEGSDDAVLLQRRLDNMNFKWSELR------KKSLNIRSHLEASSDQWKRLH 351 N G L++ ++ +N +++ + K S+ ++ + +SD K L Sbjct: 1621 N--------RGDHCRKLVEPQISELNHRFAAISHRIKTGKASIPLKELEQFNSDIQKLLE 1672 Query: 352 LSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRI 411 E+ + LK+++ ++ N+ + +EL + + + R Sbjct: 1673 PLEAEIQQGVNLKEEDFNKD------------MNEDNEGTVKELLQRGDNLQQRITDER- 1719 Query: 412 FLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDE 471 + ++ ++L Q + R+Q RK+A E++ +W + + D + +D+ Sbjct: 1720 --KREEIKIKQQLLQTKHNALKDLRSQR-----RKKALEISHQWYQYKRQADDLLKCLDD 1772 Query: 472 TLERLQELQEATDELDLKLRQAEVIK 497 ++L L E DE +K E+ K Sbjct: 1773 IEKKLASLPEPRDERKIKEIDRELQK 1798 Score = 55.8 bits (133), Expect = 2e-07 Identities = 96/533 (18%), Positives = 216/533 (40%), Gaps = 75/533 (14%) Query: 12 LADFNRAWTELTDWL----SLLDQVIKSQRVMVGDLEDINEMI----------IKQKATM 57 L FN W EL + LL+Q I+S + L I E + I K Sbjct: 1221 LETFNSRWRELHEEAVRRQKLLEQSIQSAQETEKSLHLIQESLTFIDKQLAAYIADKVDA 1280 Query: 58 QDLEQRRPQLEELITA----AQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQ 113 + Q +++ +T+ + +K +EA +R+ +Q D Q+ LQ+ Sbjct: 1281 AQMPQEAQKIQSDLTSHEISLEEMKKHNQGKEAA-------QRVLSQIDVAQKKLQDVSM 1333 Query: 114 QLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQW 173 + + + + + +E++ +L + + L + + + +Q ++ L K L + Sbjct: 1334 KFR-LFQKPANFEQRLQESKMILDEVKMHLPALETKSVEQEVVQSQLNHCVNLYKSLSEV 1392 Query: 174 QTNVDVANDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQ 233 ++ V++ ++++ ++ +++ + + + +V+ER+ LE+ +L ++ Sbjct: 1393 KSEVEMVIKTGRQIVQKKQTENPKELDERVTALKLHYNELGAKVTERKQQLEKCLKLSRK 1452 Query: 234 FPLDLEKFLAWL--TEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDV 291 ++ WL T+ E T + E + G K K+ + + +++ T+V Sbjct: 1453 MRKEMNVLTEWLAATDMELTKRSAVEGMPSNLDSEVAWG-KATQKEIEKQKVHLKSITEV 1511 Query: 292 YHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLH 351 + L+++ G + L++ +L +N W + ++ + L + Sbjct: 1512 --------GEALKTVLGKKE-TLVEDKLSLLNSNWIAVTSRAEEWLNLLLEYQKHMETFD 1562 Query: 352 LSLQELLVWLQLKD---DELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLET 408 ++ + W+ D DE ++ P Q++ DV + K EL P + ST + Sbjct: 1563 QNVDHITKWIIQADTLLDESEKKKP--------QQKEDVLKRLKAELNDIRPKVDSTRDQ 1614 Query: 409 VRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLR--------KQAEEVNTEWEKL-- 458 + + + KL EP+ R ++ ++ K+ E+ N++ +KL Sbjct: 1615 AANLMANRG-DHCRKLV-EPQISELNHRFAAISHRIKTGKASIPLKELEQFNSDIQKLLE 1672 Query: 459 ----------NLHSADWQRKIDETLE-RLQELQEATDELDLKL---RQAEVIK 497 NL D+ + ++E E ++EL + D L ++ R+ E IK Sbjct: 1673 PLEAEIQQGVNLKEEDFNKDMNEDNEGTVKELLQRGDNLQQRITDERKREEIK 1725 Score = 47.4 bits (111), Expect = 9e-05 Identities = 68/315 (21%), Positives = 125/315 (39%), Gaps = 53/315 (16%) Query: 286 EAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS-----HL 340 E H ++H + + Q + +G + + R + + + S RS HL Sbjct: 140 EEHFQLHHQMHYSQQITVSLAQGYERTSSPKPRFKSYAYTQAAYVTTSDPTRSPFPSQHL 199 Query: 341 EASSDQ------------WKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVH 388 EA D+ R +L+E+L WL +D L Q I D V+ Q H Sbjct: 200 EAPEDKSFGSSLMESEVNLDRYQTALEEVLSWLLSAEDTLQAQGEISNDVEVVKDQFHTH 259 Query: 389 RAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQA 448 + +L + + + L+ L G KL ++ EE +++Q Sbjct: 260 EGYMMDLTAHQGRVGNILQ------LGSKLIGTGKLSED------EETE------VQEQM 301 Query: 449 EEVNTEWEKLNLHSADWQRKIDETL-----ERLQELQEATDELDLKLRQAEVIKGSWQPV 503 +N+ WE L + S + Q + L ++L+EL + + + + R+ E +P+ Sbjct: 302 NLLNSRWECLRVASMEKQSNLHRVLMDLQNQKLKELNDWLTKTEERTRKMEE-----EPL 356 Query: 504 GDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLED---- 559 G L D L+ +++ K L+ + L++ VN L + + + + LE+ Sbjct: 357 GPDLED-LKRQVQQHKVLQED---LEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKV 412 Query: 560 LNTRWKLLQVAVEDR 574 L RW + EDR Sbjct: 413 LGDRWANICRWTEDR 427 Score = 35.0 bits (79), Expect = 0.44 Identities = 41/178 (23%), Positives = 78/178 (43%), Gaps = 10/178 (5%) Query: 984 LAEMENSNGSYLNDS-ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEE 1042 L ++ + G L + ISP E E+ L Q Q + L + + I + ++ Sbjct: 2144 LKQLNETGGPVLVSAPISPEEQDKLENKLKQTNLQWIKVSRALPEKQGE----IEAQIKD 2199 Query: 1043 RGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPT----SPQSPRDAEL 1098 G+LE+ L DLEE+ +L ++ Q E P ++ T + P E+ Sbjct: 2200 LGQLEKKLEDLEEQLNHLLLWLSPIRNQLEIYNQPNQEGPFDVQETEIAVQAKQPDVEEI 2259 Query: 1099 IAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPST 1156 +++ + L + K + + LED + + ++ ++RL Q L Q + TT+ + T Sbjct: 2260 LSKGQHLYKEKPATQPVKRKLEDLSSEWKA-VNRLLQELRAKQPDLAPGLTTIGASPT 2316 >gi|5032287 dystrophin Dp427p1 isoform [Homo sapiens] Length = 3681 Score = 2452 bits (6355), Expect = 0.0 Identities = 1225/1225 (100%), Positives = 1225/1225 (100%) Query: 1 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL Sbjct: 2457 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 2516 Query: 61 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK Sbjct: 2517 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 2576 Query: 121 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA Sbjct: 2577 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 2636 Query: 181 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK Sbjct: 2637 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 2696 Query: 241 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ Sbjct: 2697 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 2756 Query: 301 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW Sbjct: 2757 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 2816 Query: 361 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG Sbjct: 2817 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 2876 Query: 421 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ Sbjct: 2877 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 2936 Query: 481 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR Sbjct: 2937 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 2996 Query: 541 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP Sbjct: 2997 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 3056 Query: 601 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC Sbjct: 3057 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 3116 Query: 661 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN Sbjct: 3117 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 3176 Query: 721 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD Sbjct: 3177 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 3236 Query: 781 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR Sbjct: 3237 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 3296 Query: 841 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC Sbjct: 3297 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 3356 Query: 901 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS 960 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS Sbjct: 3357 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS 3416 Query: 961 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN 1020 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN Sbjct: 3417 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN 3476 Query: 1021 QDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLP 1080 QDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLP Sbjct: 3477 QDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLP 3536 Query: 1081 SPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQP 1140 SPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQP Sbjct: 3537 SPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQP 3596 Query: 1141 QAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVM 1200 QAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVM Sbjct: 3597 QAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVM 3656 Query: 1201 EQLNNSFPSSRGRNTPGKPMREDTM 1225 EQLNNSFPSSRGRNTPGKPMREDTM Sbjct: 3657 EQLNNSFPSSRGRNTPGKPMREDTM 3681 Score = 100 bits (249), Expect = 8e-21 Identities = 166/775 (21%), Positives = 312/775 (40%), Gaps = 89/775 (11%) Query: 20 TELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKN 79 T ++ L ++Q++ + + D ED+ + K L+Q +++ +I + + Sbjct: 2001 THVSQALLEVEQLLNAPDLCAKDFEDLFKQEESLKNIKDSLQQSSGRID-IIHSKKTAAL 2059 Query: 80 KTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEM----------LKDSTQWLEAK 129 +++ R + + + ++ QW++V + ++R+ + + +K QWL Sbjct: 2060 QSATPVERVKLQEALSQLDFQWEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIFNQWLT-- 2117 Query: 130 EEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLR 189 EAEQ L + + E+W+ Y K+L + Q QT V N ++++ Sbjct: 2118 -EAEQFLRKTQIP-ENWEHAKYK--------WYLKELQDGIGQRQTVVRTLNATGEEIIQ 2167 Query: 190 DYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAE 249 S D + ++N W+ + K++S+R+ LEE +L +F DL +F+ WL EA+ Sbjct: 2168 QSSKTDASILQEKLGSLNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEAD 2227 Query: 250 TTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGS 309 A++ + ++++L E + VK L+++ QG + L+E +L S S Sbjct: 2228 NIASIPLEPGKEQQLKEKLEQVKLLVEELPLRQG-------ILKQLNETGGPVLVSAPIS 2280 Query: 310 -DDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQE-------LLVWL 361 ++ L+ +L N +W ++ + + +EA +L L++ LL+WL Sbjct: 2281 PEEQDKLENKLKQTNLQWIKVSRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHLLLWL 2340 Query: 362 Q--LKDDELSRQAPIGGDFP------AVQ-KQNDVHRAFKR--ELKTKEPVIMSTLETVR 410 E+ Q G F AVQ KQ DV + L ++P + Sbjct: 2341 SPIRNQLEIYNQPNQEGPFDVQETEIAVQAKQPDVEEILSKGQHLYKEKPATQPVKRKLE 2400 Query: 411 IFLTEQPLEGLEKLYQEPRELPPE----------ERAQNVTRLLRKQAEEVNTEWEKLNL 460 +E + + +L QE R P+ Q VT L+ + T KL + Sbjct: 2401 DLSSE--WKAVNRLLQELRAKQPDLAPGLTTIGASPTQTVT-LVTQPVVTKETAISKLEM 2457 Query: 461 HSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKA 520 S+ ++ + + E TD L L +VIK VGDL + + + + K KA Sbjct: 2458 PSS-LMLEVPALADFNRAWTELTDWLSL---LDQVIKSQRVMVGDL--EDINEMIIKQKA 2511 Query: 521 LRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLST--LEDLNTRWKLLQVAVEDRVRQL 578 ++ + + + A+ L + T +E + +W +Q +++R +QL Sbjct: 2512 TMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQL 2571 Query: 579 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 638 +E +D S +L + + K+ + T K+TE Q DL Sbjct: 2572 NEMLKD----STQWLEAKEEAEQVLGQARAKLESW-KEGPYTVDAIQKKITETKQLAKDL 2626 Query: 639 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 698 + + + L L LL +A D H + +N I ++ Sbjct: 2627 RQWQTNV--------DVANDLALKLLRDYSADDTRKVHMITENIN-ASWRSIHKRVSERE 2677 Query: 699 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGR-----TGRIRVLSFKTGIISLCK 748 LE+ H L PL ++ L WL T T + R+L G+ L K Sbjct: 2678 AALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMK 2732 Score = 81.3 bits (199), Expect = 5e-15 Identities = 109/561 (19%), Positives = 234/561 (41%), Gaps = 59/561 (10%) Query: 22 LTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNKT 81 L W++ +D +K + +GD E + + + + + + D++ +P L + Q +KN+ Sbjct: 1056 LKKWMAEVDVFLKEEWPALGDSEILKKQLKQCRLLVSDIQTIQPSLNSVNEGGQKIKNEA 1115 Query: 82 SNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARA 141 + A + T+ ++ + QWD + + + R++ L L+ + + E + + QA Sbjct: 1116 EPEFASRLETE-LKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEE 1174 Query: 142 KLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYS--ADDTRKV 199 + T D +QK + E K+ ++ +Q + V + + ++ A + K Sbjct: 1175 EYLERDFEYKTPDELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEALKK 1234 Query: 200 HMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAE----TTANVL 255 + T N W + R++ + LEE + LEK WL E E TT N+ Sbjct: 1235 ELETLTTNYQW--LCTRLNGKCKTLEEVWACWHELLSYLEKANKWLNEVEFKLKTTENIP 1292 Query: 256 QDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLL 315 A E + E ++ LM+ +D +I +G L+ Sbjct: 1293 GGA---EEISEVLDSLENLMRHSEDNPNQIRILAQTL-------------TDGGVMDELI 1336 Query: 316 QRRLDNMNFKWSELRKKSLN----IRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQ 371 L+ N +W EL ++++ + ++++ + K LHL +QE L ++ D +L+ Sbjct: 1337 NEELETFNSRWRELHEEAVRRQKLLEQSIQSAQETEKSLHL-IQESLTFI---DKQLA-- 1390 Query: 372 APIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPREL 431 A I A Q + + I S L + I L E K + + +E Sbjct: 1391 AYIADKVDAAQMPQEAQK------------IQSDLTSHEISLEEM------KKHNQGKE- 1431 Query: 432 PPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLR 491 +R + + +K+ ++V+ ++ +L A++++++ E+ L E++ L+ K Sbjct: 1432 -AAQRVLSQIDVAQKKLQDVSMKF-RLFQKPANFEQRLQESKMILDEVKMHLPALETKSV 1489 Query: 492 QAEVIKGSWQPVGDLL--IDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQL 549 + EV++ +L + ++ +E V +I K+ + +L ++T L + Sbjct: 1490 EQEVVQSQLNHCVNLYKSLSEVKSEVEMVIKTGRQIVQ-KKQTENPKELDERVTALKLHY 1548 Query: 550 SPYNLSTLEDLNTRWKLLQVA 570 + E K L+++ Sbjct: 1549 NELGAKVTERKQQLEKCLKLS 1569 Score = 65.5 bits (158), Expect = 3e-10 Identities = 70/339 (20%), Positives = 133/339 (39%), Gaps = 22/339 (6%) Query: 3 SSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQ 62 SSLM L + A E+ WL + +++Q + D+E + + + M DL Sbjct: 328 SSLMESEVNLDRYQTALEEVLSWLLSAEDTLQAQGEISNDVEVVKDQFHTHEGYMMDLTA 387 Query: 63 RRPQLEELITAAQNL--------KNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQ 114 + ++ ++ L +T QE ++ R E ++ E Q +L Sbjct: 388 HQGRVGNILQLGSKLIGTGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLMD 447 Query: 115 L-NEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQW 173 L N+ LK+ WL EE + K+E GP ++ +++++ + K L +DL Q Sbjct: 448 LQNQKLKELNDWLTKTEERTR-------KMEEEPLGP-DLEDLKRQVQQHKVLQEDLEQE 499 Query: 174 QTNVDVANDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQ 233 Q V+ + + + T + + + W +I + +R L++ Q+ Sbjct: 500 QVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWTEDRWVLLQDILLKWQR 559 Query: 234 FPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYH 293 + F AWL+E E N + K D + +++ L+ ++E Sbjct: 560 LTEEQCLFSAWLSEKEDAVNKIHTTGFK-----DQNEMLSSLQKLAVLKADLEKKKQSMG 614 Query: 294 NLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKK 332 L Q +L +L+ + LDN W L +K Sbjct: 615 KLYSLKQDLLSTLKNKSVTQKTEAWLDNFARCWDNLVQK 653 Score = 62.0 bits (149), Expect = 3e-09 Identities = 104/571 (18%), Positives = 222/571 (38%), Gaps = 46/571 (8%) Query: 20 TELTDWLSLLDQVIKSQRVMV----GDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQ 75 TEL W++ + V++S + G+ D+ E K A ++ ++ +L++ +AQ Sbjct: 725 TELHSWITRSEAVLQSPEFAIFRKEGNFSDLKE---KVNAIEREKAEKFRKLQDASRSAQ 781 Query: 76 NLKNKTSNQEART-IITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQ 134 L + N+ I E++ ++W E + L R L E + + ++ EQ Sbjct: 782 ALVEQMVNEGVNADSIKQASEQLNSRWIEFCQLLSERLNWL-EYQNNIIAFYNQLQQLEQ 840 Query: 135 VLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYSAD 194 + A L+ P AI+ ++ K L Q ++ ++ L Sbjct: 841 MTTTAENWLKIQPTTPSEPTAIKSQLKICKDEVNRLSGLQPQIERLKIQSIALKEKGQGP 900 Query: 195 DTRKVHMITENINASWRSIHKRVSEREAALEETHRLL--QQFPLDLEKFLAWLTEAETTA 252 + ++ + V RE L+ L ++ + W+ ++ET Sbjct: 901 MFLDADFVA--FTNHFKQVFSDVQAREKELQTIFDTLPPMRYQETMSAIRTWVQQSETKL 958 Query: 253 NVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDA 312 ++ Q + ++E G + Q LQ ++ + L +++ + S+ + Sbjct: 959 SIPQLSVTDYEIMEQRLG------ELQALQSSLQEQQSGLYYLSTTVKEMSKKAP-SEIS 1011 Query: 313 VLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQA 372 Q + + +W +L + + LE ++ +++ +Q L W+ D L + Sbjct: 1012 RKYQSEFEEIEGRWKKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEW 1071 Query: 373 PIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELP 432 P GD ++KQ R +++T +P + S EG +K+ E Sbjct: 1072 PALGDSEILKKQLKQCRLLVSDIQTIQPSLNSV------------NEGGQKI---KNEAE 1116 Query: 433 PEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQ 492 PE ++ L + +E+NT+W+ + + + LE+ LQ+ E+ + Q Sbjct: 1117 PEFASR-----LETELKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQ 1171 Query: 493 A--EVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLS 550 A E ++ ++ D LQ +E++K + E + V + + + ++ Sbjct: 1172 AEEEYLERDFEYKTP---DELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVA 1228 Query: 551 PYNL-STLEDLNTRWKLLQVAVEDRVRQLHE 580 L LE L T ++ L + + + L E Sbjct: 1229 QEALKKELETLTTNYQWLCTRLNGKCKTLEE 1259 Score = 60.8 bits (146), Expect = 7e-09 Identities = 74/446 (16%), Positives = 186/446 (41%), Gaps = 40/446 (8%) Query: 58 QDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNE 117 + L + + ++E +I + + K + + + +R+ ++ ++E+ + R+QQL + Sbjct: 1506 KSLSEVKSEVEMVIKTGRQIVQKKQTENPKEL-DERVTALKLHYNELGAKVTERKQQLEK 1564 Query: 118 MLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNV 177 LK S + + + L +L + ++ K K++ + + ++ Sbjct: 1565 CLKLSRKMRKEMNVLTEWLAATDMELTKRSAVEGMPSNLDSEVAWGKATQKEIEKQKVHL 1624 Query: 178 DVANDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLD 237 ++ L +T ++ +N++W ++ R E L E + ++ F + Sbjct: 1625 KSITEVGEALKTVLGKKETLVEDKLSL-LNSNWIAVTSRAEEWLNLLLEYQKHMETFDQN 1683 Query: 238 LEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDE 297 ++ W+ +A+T L D + K++ + +K L + D++ ++++ D NL Sbjct: 1684 VDHITKWIIQADT----LLDESEKKKPQQKEDVLKRLKAELNDIRPKVDSTRDQAANLMA 1739 Query: 298 NSQKILRSLEGSDDAVLLQRRLDNMNFKWSELR------KKSLNIRSHLEASSDQWKRLH 351 N G L++ ++ +N +++ + K S+ ++ + +SD K L Sbjct: 1740 N--------RGDHCRKLVEPQISELNHRFAAISHRIKTGKASIPLKELEQFNSDIQKLLE 1791 Query: 352 LSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRI 411 E+ + LK+++ ++ N+ + +EL + + + R Sbjct: 1792 PLEAEIQQGVNLKEEDFNKD------------MNEDNEGTVKELLQRGDNLQQRITDER- 1838 Query: 412 FLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDE 471 + ++ ++L Q + R+Q RK+A E++ +W + + D + +D+ Sbjct: 1839 --KREEIKIKQQLLQTKHNALKDLRSQR-----RKKALEISHQWYQYKRQADDLLKCLDD 1891 Query: 472 TLERLQELQEATDELDLKLRQAEVIK 497 ++L L E DE +K E+ K Sbjct: 1892 IEKKLASLPEPRDERKIKEIDRELQK 1917 Score = 55.8 bits (133), Expect = 2e-07 Identities = 96/533 (18%), Positives = 216/533 (40%), Gaps = 75/533 (14%) Query: 12 LADFNRAWTELTDWL----SLLDQVIKSQRVMVGDLEDINEMI----------IKQKATM 57 L FN W EL + LL+Q I+S + L I E + I K Sbjct: 1340 LETFNSRWRELHEEAVRRQKLLEQSIQSAQETEKSLHLIQESLTFIDKQLAAYIADKVDA 1399 Query: 58 QDLEQRRPQLEELITA----AQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQ 113 + Q +++ +T+ + +K +EA +R+ +Q D Q+ LQ+ Sbjct: 1400 AQMPQEAQKIQSDLTSHEISLEEMKKHNQGKEAA-------QRVLSQIDVAQKKLQDVSM 1452 Query: 114 QLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQW 173 + + + + + +E++ +L + + L + + + +Q ++ L K L + Sbjct: 1453 KFR-LFQKPANFEQRLQESKMILDEVKMHLPALETKSVEQEVVQSQLNHCVNLYKSLSEV 1511 Query: 174 QTNVDVANDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQ 233 ++ V++ ++++ ++ +++ + + + +V+ER+ LE+ +L ++ Sbjct: 1512 KSEVEMVIKTGRQIVQKKQTENPKELDERVTALKLHYNELGAKVTERKQQLEKCLKLSRK 1571 Query: 234 FPLDLEKFLAWL--TEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDV 291 ++ WL T+ E T + E + G K K+ + + +++ T+V Sbjct: 1572 MRKEMNVLTEWLAATDMELTKRSAVEGMPSNLDSEVAWG-KATQKEIEKQKVHLKSITEV 1630 Query: 292 YHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLH 351 + L+++ G + L++ +L +N W + ++ + L + Sbjct: 1631 --------GEALKTVLGKKE-TLVEDKLSLLNSNWIAVTSRAEEWLNLLLEYQKHMETFD 1681 Query: 352 LSLQELLVWLQLKD---DELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLET 408 ++ + W+ D DE ++ P Q++ DV + K EL P + ST + Sbjct: 1682 QNVDHITKWIIQADTLLDESEKKKP--------QQKEDVLKRLKAELNDIRPKVDSTRDQ 1733 Query: 409 VRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLR--------KQAEEVNTEWEKL-- 458 + + + KL EP+ R ++ ++ K+ E+ N++ +KL Sbjct: 1734 AANLMANRG-DHCRKLV-EPQISELNHRFAAISHRIKTGKASIPLKELEQFNSDIQKLLE 1791 Query: 459 ----------NLHSADWQRKIDETLE-RLQELQEATDELDLKL---RQAEVIK 497 NL D+ + ++E E ++EL + D L ++ R+ E IK Sbjct: 1792 PLEAEIQQGVNLKEEDFNKDMNEDNEGTVKELLQRGDNLQQRITDERKREEIK 1844 Score = 47.4 bits (111), Expect = 9e-05 Identities = 68/315 (21%), Positives = 125/315 (39%), Gaps = 53/315 (16%) Query: 286 EAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS-----HL 340 E H ++H + + Q + +G + + R + + + S RS HL Sbjct: 259 EEHFQLHHQMHYSQQITVSLAQGYERTSSPKPRFKSYAYTQAAYVTTSDPTRSPFPSQHL 318 Query: 341 EASSDQ------------WKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVH 388 EA D+ R +L+E+L WL +D L Q I D V+ Q H Sbjct: 319 EAPEDKSFGSSLMESEVNLDRYQTALEEVLSWLLSAEDTLQAQGEISNDVEVVKDQFHTH 378 Query: 389 RAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQA 448 + +L + + + L+ L G KL ++ EE +++Q Sbjct: 379 EGYMMDLTAHQGRVGNILQ------LGSKLIGTGKLSED------EETE------VQEQM 420 Query: 449 EEVNTEWEKLNLHSADWQRKIDETL-----ERLQELQEATDELDLKLRQAEVIKGSWQPV 503 +N+ WE L + S + Q + L ++L+EL + + + + R+ E +P+ Sbjct: 421 NLLNSRWECLRVASMEKQSNLHRVLMDLQNQKLKELNDWLTKTEERTRKMEE-----EPL 475 Query: 504 GDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLED---- 559 G L D L+ +++ K L+ + L++ VN L + + + + LE+ Sbjct: 476 GPDLED-LKRQVQQHKVLQED---LEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKV 531 Query: 560 LNTRWKLLQVAVEDR 574 L RW + EDR Sbjct: 532 LGDRWANICRWTEDR 546 Score = 35.0 bits (79), Expect = 0.44 Identities = 41/178 (23%), Positives = 78/178 (43%), Gaps = 10/178 (5%) Query: 984 LAEMENSNGSYLNDS-ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEE 1042 L ++ + G L + ISP E E+ L Q Q + L + + I + ++ Sbjct: 2263 LKQLNETGGPVLVSAPISPEEQDKLENKLKQTNLQWIKVSRALPEKQGE----IEAQIKD 2318 Query: 1043 RGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPT----SPQSPRDAEL 1098 G+LE+ L DLEE+ +L ++ Q E P ++ T + P E+ Sbjct: 2319 LGQLEKKLEDLEEQLNHLLLWLSPIRNQLEIYNQPNQEGPFDVQETEIAVQAKQPDVEEI 2378 Query: 1099 IAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPST 1156 +++ + L + K + + LED + + ++ ++RL Q L Q + TT+ + T Sbjct: 2379 LSKGQHLYKEKPATQPVKRKLEDLSSEWKA-VNRLLQELRAKQPDLAPGLTTIGASPT 2435 >gi|5032293 dystrophin Dp140 isoform [Homo sapiens] Length = 1225 Score = 2452 bits (6355), Expect = 0.0 Identities = 1225/1225 (100%), Positives = 1225/1225 (100%) Query: 1 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL Sbjct: 1 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60 Query: 61 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK Sbjct: 61 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120 Query: 121 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA Sbjct: 121 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180 Query: 181 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK Sbjct: 181 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240 Query: 241 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ Sbjct: 241 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300 Query: 301 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW Sbjct: 301 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360 Query: 361 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG Sbjct: 361 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420 Query: 421 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ Sbjct: 421 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480 Query: 481 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR Sbjct: 481 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540 Query: 541 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP Sbjct: 541 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600 Query: 601 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC Sbjct: 601 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660 Query: 661 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN Sbjct: 661 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720 Query: 721 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD Sbjct: 721 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780 Query: 781 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR Sbjct: 781 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840 Query: 841 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC Sbjct: 841 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900 Query: 901 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS 960 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS Sbjct: 901 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS 960 Query: 961 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN 1020 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN Sbjct: 961 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN 1020 Query: 1021 QDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLP 1080 QDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLP Sbjct: 1021 QDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLP 1080 Query: 1081 SPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQP 1140 SPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQP Sbjct: 1081 SPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQP 1140 Query: 1141 QAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVM 1200 QAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVM Sbjct: 1141 QAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVM 1200 Query: 1201 EQLNNSFPSSRGRNTPGKPMREDTM 1225 EQLNNSFPSSRGRNTPGKPMREDTM Sbjct: 1201 EQLNNSFPSSRGRNTPGKPMREDTM 1225 >gi|5032285 dystrophin Dp427l isoform [Homo sapiens] Length = 3562 Score = 2452 bits (6355), Expect = 0.0 Identities = 1225/1225 (100%), Positives = 1225/1225 (100%) Query: 1 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL Sbjct: 2338 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 2397 Query: 61 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK Sbjct: 2398 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 2457 Query: 121 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA Sbjct: 2458 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 2517 Query: 181 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK Sbjct: 2518 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 2577 Query: 241 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ Sbjct: 2578 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 2637 Query: 301 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW Sbjct: 2638 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 2697 Query: 361 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG Sbjct: 2698 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 2757 Query: 421 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ Sbjct: 2758 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 2817 Query: 481 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR Sbjct: 2818 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 2877 Query: 541 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP Sbjct: 2878 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 2937 Query: 601 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC Sbjct: 2938 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 2997 Query: 661 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN Sbjct: 2998 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 3057 Query: 721 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD Sbjct: 3058 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 3117 Query: 781 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR Sbjct: 3118 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 3177 Query: 841 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC Sbjct: 3178 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 3237 Query: 901 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS 960 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS Sbjct: 3238 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS 3297 Query: 961 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN 1020 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN Sbjct: 3298 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN 3357 Query: 1021 QDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLP 1080 QDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLP Sbjct: 3358 QDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLP 3417 Query: 1081 SPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQP 1140 SPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQP Sbjct: 3418 SPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQP 3477 Query: 1141 QAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVM 1200 QAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVM Sbjct: 3478 QAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVM 3537 Query: 1201 EQLNNSFPSSRGRNTPGKPMREDTM 1225 EQLNNSFPSSRGRNTPGKPMREDTM Sbjct: 3538 EQLNNSFPSSRGRNTPGKPMREDTM 3562 Score = 100 bits (249), Expect = 8e-21 Identities = 166/775 (21%), Positives = 312/775 (40%), Gaps = 89/775 (11%) Query: 20 TELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKN 79 T ++ L ++Q++ + + D ED+ + K L+Q +++ +I + + Sbjct: 1882 THVSQALLEVEQLLNAPDLCAKDFEDLFKQEESLKNIKDSLQQSSGRID-IIHSKKTAAL 1940 Query: 80 KTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEM----------LKDSTQWLEAK 129 +++ R + + + ++ QW++V + ++R+ + + +K QWL Sbjct: 1941 QSATPVERVKLQEALSQLDFQWEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIFNQWLT-- 1998 Query: 130 EEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLR 189 EAEQ L + + E+W+ Y K+L + Q QT V N ++++ Sbjct: 1999 -EAEQFLRKTQIP-ENWEHAKYK--------WYLKELQDGIGQRQTVVRTLNATGEEIIQ 2048 Query: 190 DYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAE 249 S D + ++N W+ + K++S+R+ LEE +L +F DL +F+ WL EA+ Sbjct: 2049 QSSKTDASILQEKLGSLNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEAD 2108 Query: 250 TTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGS 309 A++ + ++++L E + VK L+++ QG + L+E +L S S Sbjct: 2109 NIASIPLEPGKEQQLKEKLEQVKLLVEELPLRQG-------ILKQLNETGGPVLVSAPIS 2161 Query: 310 -DDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQE-------LLVWL 361 ++ L+ +L N +W ++ + + +EA +L L++ LL+WL Sbjct: 2162 PEEQDKLENKLKQTNLQWIKVSRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHLLLWL 2221 Query: 362 Q--LKDDELSRQAPIGGDFP------AVQ-KQNDVHRAFKR--ELKTKEPVIMSTLETVR 410 E+ Q G F AVQ KQ DV + L ++P + Sbjct: 2222 SPIRNQLEIYNQPNQEGPFDVQETEIAVQAKQPDVEEILSKGQHLYKEKPATQPVKRKLE 2281 Query: 411 IFLTEQPLEGLEKLYQEPRELPPE----------ERAQNVTRLLRKQAEEVNTEWEKLNL 460 +E + + +L QE R P+ Q VT L+ + T KL + Sbjct: 2282 DLSSE--WKAVNRLLQELRAKQPDLAPGLTTIGASPTQTVT-LVTQPVVTKETAISKLEM 2338 Query: 461 HSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKA 520 S+ ++ + + E TD L L +VIK VGDL + + + + K KA Sbjct: 2339 PSS-LMLEVPALADFNRAWTELTDWLSL---LDQVIKSQRVMVGDL--EDINEMIIKQKA 2392 Query: 521 LRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLST--LEDLNTRWKLLQVAVEDRVRQL 578 ++ + + + A+ L + T +E + +W +Q +++R +QL Sbjct: 2393 TMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQL 2452 Query: 579 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 638 +E +D S +L + + K+ + T K+TE Q DL Sbjct: 2453 NEMLKD----STQWLEAKEEAEQVLGQARAKLESW-KEGPYTVDAIQKKITETKQLAKDL 2507 Query: 639 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 698 + + + L L LL +A D H + +N I ++ Sbjct: 2508 RQWQTNV--------DVANDLALKLLRDYSADDTRKVHMITENIN-ASWRSIHKRVSERE 2558 Query: 699 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGR-----TGRIRVLSFKTGIISLCK 748 LE+ H L PL ++ L WL T T + R+L G+ L K Sbjct: 2559 AALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMK 2613 Score = 81.3 bits (199), Expect = 5e-15 Identities = 109/561 (19%), Positives = 234/561 (41%), Gaps = 59/561 (10%) Query: 22 LTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNKT 81 L W++ +D +K + +GD E + + + + + + D++ +P L + Q +KN+ Sbjct: 937 LKKWMAEVDVFLKEEWPALGDSEILKKQLKQCRLLVSDIQTIQPSLNSVNEGGQKIKNEA 996 Query: 82 SNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARA 141 + A + T+ ++ + QWD + + + R++ L L+ + + E + + QA Sbjct: 997 EPEFASRLETE-LKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEE 1055 Query: 142 KLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYS--ADDTRKV 199 + T D +QK + E K+ ++ +Q + V + + ++ A + K Sbjct: 1056 EYLERDFEYKTPDELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEALKK 1115 Query: 200 HMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAE----TTANVL 255 + T N W + R++ + LEE + LEK WL E E TT N+ Sbjct: 1116 ELETLTTNYQW--LCTRLNGKCKTLEEVWACWHELLSYLEKANKWLNEVEFKLKTTENIP 1173 Query: 256 QDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLL 315 A E + E ++ LM+ +D +I +G L+ Sbjct: 1174 GGA---EEISEVLDSLENLMRHSEDNPNQIRILAQTL-------------TDGGVMDELI 1217 Query: 316 QRRLDNMNFKWSELRKKSLN----IRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQ 371 L+ N +W EL ++++ + ++++ + K LHL +QE L ++ D +L+ Sbjct: 1218 NEELETFNSRWRELHEEAVRRQKLLEQSIQSAQETEKSLHL-IQESLTFI---DKQLA-- 1271 Query: 372 APIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPREL 431 A I A Q + + I S L + I L E K + + +E Sbjct: 1272 AYIADKVDAAQMPQEAQK------------IQSDLTSHEISLEEM------KKHNQGKE- 1312 Query: 432 PPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLR 491 +R + + +K+ ++V+ ++ +L A++++++ E+ L E++ L+ K Sbjct: 1313 -AAQRVLSQIDVAQKKLQDVSMKF-RLFQKPANFEQRLQESKMILDEVKMHLPALETKSV 1370 Query: 492 QAEVIKGSWQPVGDLL--IDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQL 549 + EV++ +L + ++ +E V +I K+ + +L ++T L + Sbjct: 1371 EQEVVQSQLNHCVNLYKSLSEVKSEVEMVIKTGRQIVQ-KKQTENPKELDERVTALKLHY 1429 Query: 550 SPYNLSTLEDLNTRWKLLQVA 570 + E K L+++ Sbjct: 1430 NELGAKVTERKQQLEKCLKLS 1450 Score = 65.5 bits (158), Expect = 3e-10 Identities = 70/339 (20%), Positives = 133/339 (39%), Gaps = 22/339 (6%) Query: 3 SSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQ 62 SSLM L + A E+ WL + +++Q + D+E + + + M DL Sbjct: 209 SSLMESEVNLDRYQTALEEVLSWLLSAEDTLQAQGEISNDVEVVKDQFHTHEGYMMDLTA 268 Query: 63 RRPQLEELITAAQNL--------KNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQ 114 + ++ ++ L +T QE ++ R E ++ E Q +L Sbjct: 269 HQGRVGNILQLGSKLIGTGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLMD 328 Query: 115 L-NEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQW 173 L N+ LK+ WL EE + K+E GP ++ +++++ + K L +DL Q Sbjct: 329 LQNQKLKELNDWLTKTEERTR-------KMEEEPLGP-DLEDLKRQVQQHKVLQEDLEQE 380 Query: 174 QTNVDVANDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQ 233 Q V+ + + + T + + + W +I + +R L++ Q+ Sbjct: 381 QVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWTEDRWVLLQDILLKWQR 440 Query: 234 FPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYH 293 + F AWL+E E N + K D + +++ L+ ++E Sbjct: 441 LTEEQCLFSAWLSEKEDAVNKIHTTGFK-----DQNEMLSSLQKLAVLKADLEKKKQSMG 495 Query: 294 NLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKK 332 L Q +L +L+ + LDN W L +K Sbjct: 496 KLYSLKQDLLSTLKNKSVTQKTEAWLDNFARCWDNLVQK 534 Score = 62.0 bits (149), Expect = 3e-09 Identities = 104/571 (18%), Positives = 222/571 (38%), Gaps = 46/571 (8%) Query: 20 TELTDWLSLLDQVIKSQRVMV----GDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQ 75 TEL W++ + V++S + G+ D+ E K A ++ ++ +L++ +AQ Sbjct: 606 TELHSWITRSEAVLQSPEFAIFRKEGNFSDLKE---KVNAIEREKAEKFRKLQDASRSAQ 662 Query: 76 NLKNKTSNQEART-IITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQ 134 L + N+ I E++ ++W E + L R L E + + ++ EQ Sbjct: 663 ALVEQMVNEGVNADSIKQASEQLNSRWIEFCQLLSERLNWL-EYQNNIIAFYNQLQQLEQ 721 Query: 135 VLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYSAD 194 + A L+ P AI+ ++ K L Q ++ ++ L Sbjct: 722 MTTTAENWLKIQPTTPSEPTAIKSQLKICKDEVNRLSGLQPQIERLKIQSIALKEKGQGP 781 Query: 195 DTRKVHMITENINASWRSIHKRVSEREAALEETHRLL--QQFPLDLEKFLAWLTEAETTA 252 + ++ + V RE L+ L ++ + W+ ++ET Sbjct: 782 MFLDADFVA--FTNHFKQVFSDVQAREKELQTIFDTLPPMRYQETMSAIRTWVQQSETKL 839 Query: 253 NVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDA 312 ++ Q + ++E G + Q LQ ++ + L +++ + S+ + Sbjct: 840 SIPQLSVTDYEIMEQRLG------ELQALQSSLQEQQSGLYYLSTTVKEMSKKAP-SEIS 892 Query: 313 VLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQA 372 Q + + +W +L + + LE ++ +++ +Q L W+ D L + Sbjct: 893 RKYQSEFEEIEGRWKKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEW 952 Query: 373 PIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELP 432 P GD ++KQ R +++T +P + S EG +K+ E Sbjct: 953 PALGDSEILKKQLKQCRLLVSDIQTIQPSLNSV------------NEGGQKI---KNEAE 997 Query: 433 PEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQ 492 PE ++ L + +E+NT+W+ + + + LE+ LQ+ E+ + Q Sbjct: 998 PEFASR-----LETELKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQ 1052 Query: 493 A--EVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLS 550 A E ++ ++ D LQ +E++K + E + V + + + ++ Sbjct: 1053 AEEEYLERDFEYKTP---DELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVA 1109 Query: 551 PYNL-STLEDLNTRWKLLQVAVEDRVRQLHE 580 L LE L T ++ L + + + L E Sbjct: 1110 QEALKKELETLTTNYQWLCTRLNGKCKTLEE 1140 Score = 60.8 bits (146), Expect = 7e-09 Identities = 74/446 (16%), Positives = 186/446 (41%), Gaps = 40/446 (8%) Query: 58 QDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNE 117 + L + + ++E +I + + K + + + +R+ ++ ++E+ + R+QQL + Sbjct: 1387 KSLSEVKSEVEMVIKTGRQIVQKKQTENPKEL-DERVTALKLHYNELGAKVTERKQQLEK 1445 Query: 118 MLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNV 177 LK S + + + L +L + ++ K K++ + + ++ Sbjct: 1446 CLKLSRKMRKEMNVLTEWLAATDMELTKRSAVEGMPSNLDSEVAWGKATQKEIEKQKVHL 1505 Query: 178 DVANDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLD 237 ++ L +T ++ +N++W ++ R E L E + ++ F + Sbjct: 1506 KSITEVGEALKTVLGKKETLVEDKLSL-LNSNWIAVTSRAEEWLNLLLEYQKHMETFDQN 1564 Query: 238 LEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDE 297 ++ W+ +A+T L D + K++ + +K L + D++ ++++ D NL Sbjct: 1565 VDHITKWIIQADT----LLDESEKKKPQQKEDVLKRLKAELNDIRPKVDSTRDQAANLMA 1620 Query: 298 NSQKILRSLEGSDDAVLLQRRLDNMNFKWSELR------KKSLNIRSHLEASSDQWKRLH 351 N G L++ ++ +N +++ + K S+ ++ + +SD K L Sbjct: 1621 N--------RGDHCRKLVEPQISELNHRFAAISHRIKTGKASIPLKELEQFNSDIQKLLE 1672 Query: 352 LSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRI 411 E+ + LK+++ ++ N+ + +EL + + + R Sbjct: 1673 PLEAEIQQGVNLKEEDFNKD------------MNEDNEGTVKELLQRGDNLQQRITDER- 1719 Query: 412 FLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDE 471 + ++ ++L Q + R+Q RK+A E++ +W + + D + +D+ Sbjct: 1720 --KREEIKIKQQLLQTKHNALKDLRSQR-----RKKALEISHQWYQYKRQADDLLKCLDD 1772 Query: 472 TLERLQELQEATDELDLKLRQAEVIK 497 ++L L E DE +K E+ K Sbjct: 1773 IEKKLASLPEPRDERKIKEIDRELQK 1798 Score = 55.8 bits (133), Expect = 2e-07 Identities = 96/533 (18%), Positives = 216/533 (40%), Gaps = 75/533 (14%) Query: 12 LADFNRAWTELTDWL----SLLDQVIKSQRVMVGDLEDINEMI----------IKQKATM 57 L FN W EL + LL+Q I+S + L I E + I K Sbjct: 1221 LETFNSRWRELHEEAVRRQKLLEQSIQSAQETEKSLHLIQESLTFIDKQLAAYIADKVDA 1280 Query: 58 QDLEQRRPQLEELITA----AQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQ 113 + Q +++ +T+ + +K +EA +R+ +Q D Q+ LQ+ Sbjct: 1281 AQMPQEAQKIQSDLTSHEISLEEMKKHNQGKEAA-------QRVLSQIDVAQKKLQDVSM 1333 Query: 114 QLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQW 173 + + + + + +E++ +L + + L + + + +Q ++ L K L + Sbjct: 1334 KFR-LFQKPANFEQRLQESKMILDEVKMHLPALETKSVEQEVVQSQLNHCVNLYKSLSEV 1392 Query: 174 QTNVDVANDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQ 233 ++ V++ ++++ ++ +++ + + + +V+ER+ LE+ +L ++ Sbjct: 1393 KSEVEMVIKTGRQIVQKKQTENPKELDERVTALKLHYNELGAKVTERKQQLEKCLKLSRK 1452 Query: 234 FPLDLEKFLAWL--TEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDV 291 ++ WL T+ E T + E + G K K+ + + +++ T+V Sbjct: 1453 MRKEMNVLTEWLAATDMELTKRSAVEGMPSNLDSEVAWG-KATQKEIEKQKVHLKSITEV 1511 Query: 292 YHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLH 351 + L+++ G + L++ +L +N W + ++ + L + Sbjct: 1512 --------GEALKTVLGKKE-TLVEDKLSLLNSNWIAVTSRAEEWLNLLLEYQKHMETFD 1562 Query: 352 LSLQELLVWLQLKD---DELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLET 408 ++ + W+ D DE ++ P Q++ DV + K EL P + ST + Sbjct: 1563 QNVDHITKWIIQADTLLDESEKKKP--------QQKEDVLKRLKAELNDIRPKVDSTRDQ 1614 Query: 409 VRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLR--------KQAEEVNTEWEKL-- 458 + + + KL EP+ R ++ ++ K+ E+ N++ +KL Sbjct: 1615 AANLMANRG-DHCRKLV-EPQISELNHRFAAISHRIKTGKASIPLKELEQFNSDIQKLLE 1672 Query: 459 ----------NLHSADWQRKIDETLE-RLQELQEATDELDLKL---RQAEVIK 497 NL D+ + ++E E ++EL + D L ++ R+ E IK Sbjct: 1673 PLEAEIQQGVNLKEEDFNKDMNEDNEGTVKELLQRGDNLQQRITDERKREEIK 1725 Score = 47.4 bits (111), Expect = 9e-05 Identities = 68/315 (21%), Positives = 125/315 (39%), Gaps = 53/315 (16%) Query: 286 EAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS-----HL 340 E H ++H + + Q + +G + + R + + + S RS HL Sbjct: 140 EEHFQLHHQMHYSQQITVSLAQGYERTSSPKPRFKSYAYTQAAYVTTSDPTRSPFPSQHL 199 Query: 341 EASSDQ------------WKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVH 388 EA D+ R +L+E+L WL +D L Q I D V+ Q H Sbjct: 200 EAPEDKSFGSSLMESEVNLDRYQTALEEVLSWLLSAEDTLQAQGEISNDVEVVKDQFHTH 259 Query: 389 RAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQA 448 + +L + + + L+ L G KL ++ EE +++Q Sbjct: 260 EGYMMDLTAHQGRVGNILQ------LGSKLIGTGKLSED------EETE------VQEQM 301 Query: 449 EEVNTEWEKLNLHSADWQRKIDETL-----ERLQELQEATDELDLKLRQAEVIKGSWQPV 503 +N+ WE L + S + Q + L ++L+EL + + + + R+ E +P+ Sbjct: 302 NLLNSRWECLRVASMEKQSNLHRVLMDLQNQKLKELNDWLTKTEERTRKMEE-----EPL 356 Query: 504 GDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLED---- 559 G L D L+ +++ K L+ + L++ VN L + + + + LE+ Sbjct: 357 GPDLED-LKRQVQQHKVLQED---LEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKV 412 Query: 560 LNTRWKLLQVAVEDR 574 L RW + EDR Sbjct: 413 LGDRWANICRWTEDR 427 Score = 35.0 bits (79), Expect = 0.44 Identities = 41/178 (23%), Positives = 78/178 (43%), Gaps = 10/178 (5%) Query: 984 LAEMENSNGSYLNDS-ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEE 1042 L ++ + G L + ISP E E+ L Q Q + L + + I + ++ Sbjct: 2144 LKQLNETGGPVLVSAPISPEEQDKLENKLKQTNLQWIKVSRALPEKQGE----IEAQIKD 2199 Query: 1043 RGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPT----SPQSPRDAEL 1098 G+LE+ L DLEE+ +L ++ Q E P ++ T + P E+ Sbjct: 2200 LGQLEKKLEDLEEQLNHLLLWLSPIRNQLEIYNQPNQEGPFDVQETEIAVQAKQPDVEEI 2259 Query: 1099 IAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPST 1156 +++ + L + K + + LED + + ++ ++RL Q L Q + TT+ + T Sbjct: 2260 LSKGQHLYKEKPATQPVKRKLEDLSSEWKA-VNRLLQELRAKQPDLAPGLTTIGASPT 2316 >gi|5032283 dystrophin Dp427m isoform [Homo sapiens] Length = 3685 Score = 2452 bits (6355), Expect = 0.0 Identities = 1225/1225 (100%), Positives = 1225/1225 (100%) Query: 1 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL Sbjct: 2461 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 2520 Query: 61 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK Sbjct: 2521 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 2580 Query: 121 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA Sbjct: 2581 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 2640 Query: 181 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK Sbjct: 2641 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 2700 Query: 241 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ Sbjct: 2701 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 2760 Query: 301 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW Sbjct: 2761 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 2820 Query: 361 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG Sbjct: 2821 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 2880 Query: 421 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ Sbjct: 2881 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 2940 Query: 481 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR Sbjct: 2941 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 3000 Query: 541 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP Sbjct: 3001 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 3060 Query: 601 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC Sbjct: 3061 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 3120 Query: 661 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN Sbjct: 3121 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 3180 Query: 721 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD Sbjct: 3181 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 3240 Query: 781 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR Sbjct: 3241 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 3300 Query: 841 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC Sbjct: 3301 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 3360 Query: 901 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS 960 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS Sbjct: 3361 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS 3420 Query: 961 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN 1020 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN Sbjct: 3421 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN 3480 Query: 1021 QDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLP 1080 QDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLP Sbjct: 3481 QDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLP 3540 Query: 1081 SPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQP 1140 SPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQP Sbjct: 3541 SPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQP 3600 Query: 1141 QAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVM 1200 QAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVM Sbjct: 3601 QAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVM 3660 Query: 1201 EQLNNSFPSSRGRNTPGKPMREDTM 1225 EQLNNSFPSSRGRNTPGKPMREDTM Sbjct: 3661 EQLNNSFPSSRGRNTPGKPMREDTM 3685 Score = 100 bits (249), Expect = 8e-21 Identities = 166/775 (21%), Positives = 312/775 (40%), Gaps = 89/775 (11%) Query: 20 TELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKN 79 T ++ L ++Q++ + + D ED+ + K L+Q +++ +I + + Sbjct: 2005 THVSQALLEVEQLLNAPDLCAKDFEDLFKQEESLKNIKDSLQQSSGRID-IIHSKKTAAL 2063 Query: 80 KTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEM----------LKDSTQWLEAK 129 +++ R + + + ++ QW++V + ++R+ + + +K QWL Sbjct: 2064 QSATPVERVKLQEALSQLDFQWEKVNKMYKDRQGRFDRSVEKWRRFHYDIKIFNQWLT-- 2121 Query: 130 EEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLR 189 EAEQ L + + E+W+ Y K+L + Q QT V N ++++ Sbjct: 2122 -EAEQFLRKTQIP-ENWEHAKYK--------WYLKELQDGIGQRQTVVRTLNATGEEIIQ 2171 Query: 190 DYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAE 249 S D + ++N W+ + K++S+R+ LEE +L +F DL +F+ WL EA+ Sbjct: 2172 QSSKTDASILQEKLGSLNLRWQEVCKQLSDRKKRLEEQKNILSEFQRDLNEFVLWLEEAD 2231 Query: 250 TTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGS 309 A++ + ++++L E + VK L+++ QG + L+E +L S S Sbjct: 2232 NIASIPLEPGKEQQLKEKLEQVKLLVEELPLRQG-------ILKQLNETGGPVLVSAPIS 2284 Query: 310 -DDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQE-------LLVWL 361 ++ L+ +L N +W ++ + + +EA +L L++ LL+WL Sbjct: 2285 PEEQDKLENKLKQTNLQWIKVSRALPEKQGEIEAQIKDLGQLEKKLEDLEEQLNHLLLWL 2344 Query: 362 Q--LKDDELSRQAPIGGDFP------AVQ-KQNDVHRAFKR--ELKTKEPVIMSTLETVR 410 E+ Q G F AVQ KQ DV + L ++P + Sbjct: 2345 SPIRNQLEIYNQPNQEGPFDVQETEIAVQAKQPDVEEILSKGQHLYKEKPATQPVKRKLE 2404 Query: 411 IFLTEQPLEGLEKLYQEPRELPPE----------ERAQNVTRLLRKQAEEVNTEWEKLNL 460 +E + + +L QE R P+ Q VT L+ + T KL + Sbjct: 2405 DLSSE--WKAVNRLLQELRAKQPDLAPGLTTIGASPTQTVT-LVTQPVVTKETAISKLEM 2461 Query: 461 HSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKA 520 S+ ++ + + E TD L L +VIK VGDL + + + + K KA Sbjct: 2462 PSS-LMLEVPALADFNRAWTELTDWLSL---LDQVIKSQRVMVGDL--EDINEMIIKQKA 2515 Query: 521 LRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLST--LEDLNTRWKLLQVAVEDRVRQL 578 ++ + + + A+ L + T +E + +W +Q +++R +QL Sbjct: 2516 TMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQL 2575 Query: 579 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 638 +E +D S +L + + K+ + T K+TE Q DL Sbjct: 2576 NEMLKD----STQWLEAKEEAEQVLGQARAKLESW-KEGPYTVDAIQKKITETKQLAKDL 2630 Query: 639 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 698 + + + L L LL +A D H + +N I ++ Sbjct: 2631 RQWQTNV--------DVANDLALKLLRDYSADDTRKVHMITENIN-ASWRSIHKRVSERE 2681 Query: 699 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGR-----TGRIRVLSFKTGIISLCK 748 LE+ H L PL ++ L WL T T + R+L G+ L K Sbjct: 2682 AALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMK 2736 Score = 81.3 bits (199), Expect = 5e-15 Identities = 109/561 (19%), Positives = 234/561 (41%), Gaps = 59/561 (10%) Query: 22 LTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNKT 81 L W++ +D +K + +GD E + + + + + + D++ +P L + Q +KN+ Sbjct: 1060 LKKWMAEVDVFLKEEWPALGDSEILKKQLKQCRLLVSDIQTIQPSLNSVNEGGQKIKNEA 1119 Query: 82 SNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARA 141 + A + T+ ++ + QWD + + + R++ L L+ + + E + + QA Sbjct: 1120 EPEFASRLETE-LKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEE 1178 Query: 142 KLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYS--ADDTRKV 199 + T D +QK + E K+ ++ +Q + V + + ++ A + K Sbjct: 1179 EYLERDFEYKTPDELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEALKK 1238 Query: 200 HMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAE----TTANVL 255 + T N W + R++ + LEE + LEK WL E E TT N+ Sbjct: 1239 ELETLTTNYQW--LCTRLNGKCKTLEEVWACWHELLSYLEKANKWLNEVEFKLKTTENIP 1296 Query: 256 QDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLL 315 A E + E ++ LM+ +D +I +G L+ Sbjct: 1297 GGA---EEISEVLDSLENLMRHSEDNPNQIRILAQTL-------------TDGGVMDELI 1340 Query: 316 QRRLDNMNFKWSELRKKSLN----IRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQ 371 L+ N +W EL ++++ + ++++ + K LHL +QE L ++ D +L+ Sbjct: 1341 NEELETFNSRWRELHEEAVRRQKLLEQSIQSAQETEKSLHL-IQESLTFI---DKQLA-- 1394 Query: 372 APIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPREL 431 A I A Q + + I S L + I L E K + + +E Sbjct: 1395 AYIADKVDAAQMPQEAQK------------IQSDLTSHEISLEEM------KKHNQGKE- 1435 Query: 432 PPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLR 491 +R + + +K+ ++V+ ++ +L A++++++ E+ L E++ L+ K Sbjct: 1436 -AAQRVLSQIDVAQKKLQDVSMKF-RLFQKPANFEQRLQESKMILDEVKMHLPALETKSV 1493 Query: 492 QAEVIKGSWQPVGDLL--IDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQL 549 + EV++ +L + ++ +E V +I K+ + +L ++T L + Sbjct: 1494 EQEVVQSQLNHCVNLYKSLSEVKSEVEMVIKTGRQIVQ-KKQTENPKELDERVTALKLHY 1552 Query: 550 SPYNLSTLEDLNTRWKLLQVA 570 + E K L+++ Sbjct: 1553 NELGAKVTERKQQLEKCLKLS 1573 Score = 65.5 bits (158), Expect = 3e-10 Identities = 70/339 (20%), Positives = 133/339 (39%), Gaps = 22/339 (6%) Query: 3 SSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQ 62 SSLM L + A E+ WL + +++Q + D+E + + + M DL Sbjct: 332 SSLMESEVNLDRYQTALEEVLSWLLSAEDTLQAQGEISNDVEVVKDQFHTHEGYMMDLTA 391 Query: 63 RRPQLEELITAAQNL--------KNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQ 114 + ++ ++ L +T QE ++ R E ++ E Q +L Sbjct: 392 HQGRVGNILQLGSKLIGTGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLMD 451 Query: 115 L-NEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQW 173 L N+ LK+ WL EE + K+E GP ++ +++++ + K L +DL Q Sbjct: 452 LQNQKLKELNDWLTKTEERTR-------KMEEEPLGP-DLEDLKRQVQQHKVLQEDLEQE 503 Query: 174 QTNVDVANDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQ 233 Q V+ + + + T + + + W +I + +R L++ Q+ Sbjct: 504 QVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANICRWTEDRWVLLQDILLKWQR 563 Query: 234 FPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYH 293 + F AWL+E E N + K D + +++ L+ ++E Sbjct: 564 LTEEQCLFSAWLSEKEDAVNKIHTTGFK-----DQNEMLSSLQKLAVLKADLEKKKQSMG 618 Query: 294 NLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKK 332 L Q +L +L+ + LDN W L +K Sbjct: 619 KLYSLKQDLLSTLKNKSVTQKTEAWLDNFARCWDNLVQK 657 Score = 62.0 bits (149), Expect = 3e-09 Identities = 104/571 (18%), Positives = 222/571 (38%), Gaps = 46/571 (8%) Query: 20 TELTDWLSLLDQVIKSQRVMV----GDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQ 75 TEL W++ + V++S + G+ D+ E K A ++ ++ +L++ +AQ Sbjct: 729 TELHSWITRSEAVLQSPEFAIFRKEGNFSDLKE---KVNAIEREKAEKFRKLQDASRSAQ 785 Query: 76 NLKNKTSNQEART-IITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQ 134 L + N+ I E++ ++W E + L R L E + + ++ EQ Sbjct: 786 ALVEQMVNEGVNADSIKQASEQLNSRWIEFCQLLSERLNWL-EYQNNIIAFYNQLQQLEQ 844 Query: 135 VLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYSAD 194 + A L+ P AI+ ++ K L Q ++ ++ L Sbjct: 845 MTTTAENWLKIQPTTPSEPTAIKSQLKICKDEVNRLSGLQPQIERLKIQSIALKEKGQGP 904 Query: 195 DTRKVHMITENINASWRSIHKRVSEREAALEETHRLL--QQFPLDLEKFLAWLTEAETTA 252 + ++ + V RE L+ L ++ + W+ ++ET Sbjct: 905 MFLDADFVA--FTNHFKQVFSDVQAREKELQTIFDTLPPMRYQETMSAIRTWVQQSETKL 962 Query: 253 NVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDA 312 ++ Q + ++E G + Q LQ ++ + L +++ + S+ + Sbjct: 963 SIPQLSVTDYEIMEQRLG------ELQALQSSLQEQQSGLYYLSTTVKEMSKKAP-SEIS 1015 Query: 313 VLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQA 372 Q + + +W +L + + LE ++ +++ +Q L W+ D L + Sbjct: 1016 RKYQSEFEEIEGRWKKLSSQLVEHCQKLEEQMNKLRKIQNHIQTLKKWMAEVDVFLKEEW 1075 Query: 373 PIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELP 432 P GD ++KQ R +++T +P + S EG +K+ E Sbjct: 1076 PALGDSEILKKQLKQCRLLVSDIQTIQPSLNSV------------NEGGQKI---KNEAE 1120 Query: 433 PEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQ 492 PE ++ L + +E+NT+W+ + + + LE+ LQ+ E+ + Q Sbjct: 1121 PEFASR-----LETELKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQ 1175 Query: 493 A--EVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLS 550 A E ++ ++ D LQ +E++K + E + V + + + ++ Sbjct: 1176 AEEEYLERDFEYKTP---DELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVA 1232 Query: 551 PYNL-STLEDLNTRWKLLQVAVEDRVRQLHE 580 L LE L T ++ L + + + L E Sbjct: 1233 QEALKKELETLTTNYQWLCTRLNGKCKTLEE 1263 Score = 60.8 bits (146), Expect = 7e-09 Identities = 74/446 (16%), Positives = 186/446 (41%), Gaps = 40/446 (8%) Query: 58 QDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNE 117 + L + + ++E +I + + K + + + +R+ ++ ++E+ + R+QQL + Sbjct: 1510 KSLSEVKSEVEMVIKTGRQIVQKKQTENPKEL-DERVTALKLHYNELGAKVTERKQQLEK 1568 Query: 118 MLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNV 177 LK S + + + L +L + ++ K K++ + + ++ Sbjct: 1569 CLKLSRKMRKEMNVLTEWLAATDMELTKRSAVEGMPSNLDSEVAWGKATQKEIEKQKVHL 1628 Query: 178 DVANDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLD 237 ++ L +T ++ +N++W ++ R E L E + ++ F + Sbjct: 1629 KSITEVGEALKTVLGKKETLVEDKLSL-LNSNWIAVTSRAEEWLNLLLEYQKHMETFDQN 1687 Query: 238 LEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDE 297 ++ W+ +A+T L D + K++ + +K L + D++ ++++ D NL Sbjct: 1688 VDHITKWIIQADT----LLDESEKKKPQQKEDVLKRLKAELNDIRPKVDSTRDQAANLMA 1743 Query: 298 NSQKILRSLEGSDDAVLLQRRLDNMNFKWSELR------KKSLNIRSHLEASSDQWKRLH 351 N G L++ ++ +N +++ + K S+ ++ + +SD K L Sbjct: 1744 N--------RGDHCRKLVEPQISELNHRFAAISHRIKTGKASIPLKELEQFNSDIQKLLE 1795 Query: 352 LSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRI 411 E+ + LK+++ ++ N+ + +EL + + + R Sbjct: 1796 PLEAEIQQGVNLKEEDFNKD------------MNEDNEGTVKELLQRGDNLQQRITDER- 1842 Query: 412 FLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDE 471 + ++ ++L Q + R+Q RK+A E++ +W + + D + +D+ Sbjct: 1843 --KREEIKIKQQLLQTKHNALKDLRSQR-----RKKALEISHQWYQYKRQADDLLKCLDD 1895 Query: 472 TLERLQELQEATDELDLKLRQAEVIK 497 ++L L E DE +K E+ K Sbjct: 1896 IEKKLASLPEPRDERKIKEIDRELQK 1921 Score = 55.8 bits (133), Expect = 2e-07 Identities = 96/533 (18%), Positives = 216/533 (40%), Gaps = 75/533 (14%) Query: 12 LADFNRAWTELTDWL----SLLDQVIKSQRVMVGDLEDINEMI----------IKQKATM 57 L FN W EL + LL+Q I+S + L I E + I K Sbjct: 1344 LETFNSRWRELHEEAVRRQKLLEQSIQSAQETEKSLHLIQESLTFIDKQLAAYIADKVDA 1403 Query: 58 QDLEQRRPQLEELITA----AQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQ 113 + Q +++ +T+ + +K +EA +R+ +Q D Q+ LQ+ Sbjct: 1404 AQMPQEAQKIQSDLTSHEISLEEMKKHNQGKEAA-------QRVLSQIDVAQKKLQDVSM 1456 Query: 114 QLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQW 173 + + + + + +E++ +L + + L + + + +Q ++ L K L + Sbjct: 1457 KFR-LFQKPANFEQRLQESKMILDEVKMHLPALETKSVEQEVVQSQLNHCVNLYKSLSEV 1515 Query: 174 QTNVDVANDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQ 233 ++ V++ ++++ ++ +++ + + + +V+ER+ LE+ +L ++ Sbjct: 1516 KSEVEMVIKTGRQIVQKKQTENPKELDERVTALKLHYNELGAKVTERKQQLEKCLKLSRK 1575 Query: 234 FPLDLEKFLAWL--TEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDV 291 ++ WL T+ E T + E + G K K+ + + +++ T+V Sbjct: 1576 MRKEMNVLTEWLAATDMELTKRSAVEGMPSNLDSEVAWG-KATQKEIEKQKVHLKSITEV 1634 Query: 292 YHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLH 351 + L+++ G + L++ +L +N W + ++ + L + Sbjct: 1635 --------GEALKTVLGKKE-TLVEDKLSLLNSNWIAVTSRAEEWLNLLLEYQKHMETFD 1685 Query: 352 LSLQELLVWLQLKD---DELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLET 408 ++ + W+ D DE ++ P Q++ DV + K EL P + ST + Sbjct: 1686 QNVDHITKWIIQADTLLDESEKKKP--------QQKEDVLKRLKAELNDIRPKVDSTRDQ 1737 Query: 409 VRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLR--------KQAEEVNTEWEKL-- 458 + + + KL EP+ R ++ ++ K+ E+ N++ +KL Sbjct: 1738 AANLMANRG-DHCRKLV-EPQISELNHRFAAISHRIKTGKASIPLKELEQFNSDIQKLLE 1795 Query: 459 ----------NLHSADWQRKIDETLE-RLQELQEATDELDLKL---RQAEVIK 497 NL D+ + ++E E ++EL + D L ++ R+ E IK Sbjct: 1796 PLEAEIQQGVNLKEEDFNKDMNEDNEGTVKELLQRGDNLQQRITDERKREEIK 1848 Score = 47.4 bits (111), Expect = 9e-05 Identities = 68/315 (21%), Positives = 125/315 (39%), Gaps = 53/315 (16%) Query: 286 EAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS-----HL 340 E H ++H + + Q + +G + + R + + + S RS HL Sbjct: 263 EEHFQLHHQMHYSQQITVSLAQGYERTSSPKPRFKSYAYTQAAYVTTSDPTRSPFPSQHL 322 Query: 341 EASSDQ------------WKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVH 388 EA D+ R +L+E+L WL +D L Q I D V+ Q H Sbjct: 323 EAPEDKSFGSSLMESEVNLDRYQTALEEVLSWLLSAEDTLQAQGEISNDVEVVKDQFHTH 382 Query: 389 RAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQA 448 + +L + + + L+ L G KL ++ EE +++Q Sbjct: 383 EGYMMDLTAHQGRVGNILQ------LGSKLIGTGKLSED------EETE------VQEQM 424 Query: 449 EEVNTEWEKLNLHSADWQRKIDETL-----ERLQELQEATDELDLKLRQAEVIKGSWQPV 503 +N+ WE L + S + Q + L ++L+EL + + + + R+ E +P+ Sbjct: 425 NLLNSRWECLRVASMEKQSNLHRVLMDLQNQKLKELNDWLTKTEERTRKMEE-----EPL 479 Query: 504 GDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLED---- 559 G L D L+ +++ K L+ + L++ VN L + + + + LE+ Sbjct: 480 GPDLED-LKRQVQQHKVLQED---LEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKV 535 Query: 560 LNTRWKLLQVAVEDR 574 L RW + EDR Sbjct: 536 LGDRWANICRWTEDR 550 Score = 35.0 bits (79), Expect = 0.44 Identities = 41/178 (23%), Positives = 78/178 (43%), Gaps = 10/178 (5%) Query: 984 LAEMENSNGSYLNDS-ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEE 1042 L ++ + G L + ISP E E+ L Q Q + L + + I + ++ Sbjct: 2267 LKQLNETGGPVLVSAPISPEEQDKLENKLKQTNLQWIKVSRALPEKQGE----IEAQIKD 2322 Query: 1043 RGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPT----SPQSPRDAEL 1098 G+LE+ L DLEE+ +L ++ Q E P ++ T + P E+ Sbjct: 2323 LGQLEKKLEDLEEQLNHLLLWLSPIRNQLEIYNQPNQEGPFDVQETEIAVQAKQPDVEEI 2382 Query: 1099 IAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPST 1156 +++ + L + K + + LED + + ++ ++RL Q L Q + TT+ + T Sbjct: 2383 LSKGQHLYKEKPATQPVKRKLEDLSSEWKA-VNRLLQELRAKQPDLAPGLTTIGASPT 2439 >gi|5032309 dystrophin Dp140b isoform [Homo sapiens] Length = 1243 Score = 2427 bits (6289), Expect = 0.0 Identities = 1213/1214 (99%), Positives = 1213/1214 (99%) Query: 1 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL Sbjct: 1 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60 Query: 61 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK Sbjct: 61 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120 Query: 121 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA Sbjct: 121 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180 Query: 181 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK Sbjct: 181 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240 Query: 241 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ Sbjct: 241 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300 Query: 301 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW Sbjct: 301 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360 Query: 361 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG Sbjct: 361 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420 Query: 421 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ Sbjct: 421 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480 Query: 481 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR Sbjct: 481 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540 Query: 541 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP Sbjct: 541 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600 Query: 601 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC Sbjct: 601 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660 Query: 661 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN Sbjct: 661 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720 Query: 721 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD Sbjct: 721 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780 Query: 781 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR Sbjct: 781 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840 Query: 841 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC Sbjct: 841 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900 Query: 901 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS 960 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS Sbjct: 901 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS 960 Query: 961 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN 1020 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN Sbjct: 961 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN 1020 Query: 1021 QDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLP 1080 QDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLP Sbjct: 1021 QDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLP 1080 Query: 1081 SPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQP 1140 SPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQP Sbjct: 1081 SPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQP 1140 Query: 1141 QAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVM 1200 QAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVM Sbjct: 1141 QAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVM 1200 Query: 1201 EQLNNSFPSSRGRN 1214 EQLNNSFPSSRG N Sbjct: 1201 EQLNNSFPSSRGHN 1214 >gi|5032311 dystrophin Dp140ab isoform [Homo sapiens] Length = 1230 Score = 2390 bits (6193), Expect = 0.0 Identities = 1200/1214 (98%), Positives = 1200/1214 (98%), Gaps = 13/1214 (1%) Query: 1 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL Sbjct: 1 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60 Query: 61 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK Sbjct: 61 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120 Query: 121 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA Sbjct: 121 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180 Query: 181 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK Sbjct: 181 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240 Query: 241 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ Sbjct: 241 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300 Query: 301 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW Sbjct: 301 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360 Query: 361 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG Sbjct: 361 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420 Query: 421 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ Sbjct: 421 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480 Query: 481 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR Sbjct: 481 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540 Query: 541 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP Sbjct: 541 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600 Query: 601 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC Sbjct: 601 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660 Query: 661 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN Sbjct: 661 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720 Query: 721 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD Sbjct: 721 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780 Query: 781 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR Sbjct: 781 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840 Query: 841 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC Sbjct: 841 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900 Query: 901 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS 960 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET Sbjct: 901 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET------------ 948 Query: 961 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN 1020 PASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN Sbjct: 949 -PASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN 1007 Query: 1021 QDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLP 1080 QDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLP Sbjct: 1008 QDSPLSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLP 1067 Query: 1081 SPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQP 1140 SPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQP Sbjct: 1068 SPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQP 1127 Query: 1141 QAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVM 1200 QAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVM Sbjct: 1128 QAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVM 1187 Query: 1201 EQLNNSFPSSRGRN 1214 EQLNNSFPSSRG N Sbjct: 1188 EQLNNSFPSSRGHN 1201 >gi|5032313 dystrophin Dp140bc isoform [Homo sapiens] Length = 1133 Score = 1908 bits (4943), Expect = 0.0 Identities = 970/1073 (90%), Positives = 988/1073 (92%), Gaps = 52/1073 (4%) Query: 1 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL Sbjct: 1 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60 Query: 61 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK Sbjct: 61 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120 Query: 121 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA Sbjct: 121 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180 Query: 181 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK Sbjct: 181 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240 Query: 241 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ Sbjct: 241 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300 Query: 301 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW Sbjct: 301 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360 Query: 361 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG Sbjct: 361 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420 Query: 421 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ Sbjct: 421 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480 Query: 481 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR Sbjct: 481 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540 Query: 541 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP Sbjct: 541 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600 Query: 601 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC Sbjct: 601 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660 Query: 661 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN Sbjct: 661 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720 Query: 721 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD Sbjct: 721 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780 Query: 781 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR Sbjct: 781 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840 Query: 841 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC Sbjct: 841 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900 Query: 901 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDS 960 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET + Sbjct: 901 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETNL---------- 950 Query: 961 APASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLN 1020 Q +D + EH L+ SP E + Sbjct: 951 ------QAEYDRLKQQHEHKG-------------LSPLPSPPEMMP-------------- 977 Query: 1021 QDSPLSQPRSPAQILISLES----EERGELERILADLEEENRNLQAEYDRLKQ 1069 + P+SP + E+ + +G LE + LE+ N+ L+++ RL+Q Sbjct: 978 -----TSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQ 1025 Score = 306 bits (785), Expect = 6e-83 Identities = 158/164 (96%), Positives = 159/164 (96%), Gaps = 2/164 (1%) Query: 1053 LEEENR--NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 1110 LE +N NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG Sbjct: 941 LEGDNMETNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKG 1000 Query: 1111 RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 1170 RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR Sbjct: 1001 RLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLR 1060 Query: 1171 VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRN 1214 VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRG N Sbjct: 1061 VVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHN 1104 >gi|5032295 dystrophin Dp116 isoform [Homo sapiens] Length = 956 Score = 1907 bits (4939), Expect = 0.0 Identities = 946/947 (99%), Positives = 947/947 (100%) Query: 279 QDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 338 +DLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS Sbjct: 10 KDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 69 Query: 339 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 398 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK Sbjct: 70 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 129 Query: 399 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL 458 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL Sbjct: 130 EPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKL 189 Query: 459 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV 518 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV Sbjct: 190 NLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKV 249 Query: 519 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL 578 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL Sbjct: 250 KALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL 309 Query: 579 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 638 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL Sbjct: 310 HEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADL 369 Query: 639 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 698 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY Sbjct: 370 NNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIY 429 Query: 699 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL 758 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL Sbjct: 430 DRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYL 489 Query: 759 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA 818 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA Sbjct: 490 FKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEA 549 Query: 819 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ 878 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ Sbjct: 550 ALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQ 609 Query: 879 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ 938 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ Sbjct: 610 SCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ 669 Query: 939 TVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS 998 TVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS Sbjct: 670 TVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDS 729 Query: 999 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENR 1058 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENR Sbjct: 730 ISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLEEENR 789 Query: 1059 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI 1118 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI Sbjct: 790 NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQI 849 Query: 1119 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD 1178 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD Sbjct: 850 LEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSD 909 Query: 1179 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM 1225 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM Sbjct: 910 SMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM 956 Score = 67.8 bits (164), Expect = 6e-11 Identities = 53/235 (22%), Positives = 99/235 (42%), Gaps = 33/235 (14%) Query: 21 ELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQ-------------- 66 EL WL L D + Q + GD + + +A ++L+ + P Sbjct: 87 ELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTE 146 Query: 67 -----LEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKD 121 LE+L + L + Q ++ + E + +W+++ H + +++++E L+ Sbjct: 147 QPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLER 206 Query: 122 STQWLEAKEEAEQVLGQARAKLESWKE-GPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180 + EA +E + L QA SW+ G +D++Q + + K L ++ + NV Sbjct: 207 LQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHV 266 Query: 181 NDLALKL------LRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHR 229 NDLA +L L Y+ E++N W+ + V +R L E HR Sbjct: 267 NDLARQLTTLGIQLSPYNLSTL-------EDLNTRWKLLQVAVEDRVRQLHEAHR 314 Score = 40.0 bits (92), Expect = 0.014 Identities = 70/329 (21%), Positives = 138/329 (41%), Gaps = 52/329 (15%) Query: 168 KDLR-QWQTNVDVANDL---ALKLLRDYS-ADDTRKVHMITENINASWRSIHKRVSEREA 222 KDL+ + + + DV ++L + K+LR +DD + +N+N W + K+ + Sbjct: 10 KDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRS 69 Query: 223 ALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQ 282 LE + ++ L L++ L WL + + +R+ + D V++ + + Sbjct: 70 HLEASSDQWKRLHLSLQELLVWLQLKD------DELSRQAPIGGDFPAVQKQNDVHRAFK 123 Query: 283 GEIEAHTDVYHNLDENSQKIL--RSLEGSDDAVLLQRRLDNMNFKWSELRKKSLN--IRS 338 E++ V + E + L + LEG + R L E R +++ +R Sbjct: 124 RELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELP------PEERAQNVTRLLRK 177 Query: 339 HLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTK 398 E + +W++L+L + W + D+ L R +Q+ D + +LK + Sbjct: 178 QAEEVNTEWEKLNLHSAD---WQRKIDETLER-------LQELQEATD-----ELDLKLR 222 Query: 399 E-PVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPP-EERAQNVTRLLRK---------- 446 + VI + + V L + + LEK+ E+ P +E +V L R+ Sbjct: 223 QAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSP 282 Query: 447 ----QAEEVNTEWEKLNLHSADWQRKIDE 471 E++NT W+ L + D R++ E Sbjct: 283 YNLSTLEDLNTRWKLLQVAVEDRVRQLHE 311 >gi|5032307 dystrophin Dp140c isoform [Homo sapiens] Length = 1105 Score = 1888 bits (4891), Expect = 0.0 Identities = 947/975 (97%), Positives = 952/975 (97%), Gaps = 4/975 (0%) Query: 1 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL Sbjct: 1 MPSSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDL 60 Query: 61 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK Sbjct: 61 EQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLK 120 Query: 121 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA Sbjct: 121 DSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180 Query: 181 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK Sbjct: 181 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEK 240 Query: 241 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ Sbjct: 241 FLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQ 300 Query: 301 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW Sbjct: 301 KILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVW 360 Query: 361 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG Sbjct: 361 LQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEG 420 Query: 421 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ Sbjct: 421 LEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQ 480 Query: 481 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR Sbjct: 481 EATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLAR 540 Query: 541 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP Sbjct: 541 QLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGP 600 Query: 601 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC Sbjct: 601 WERAISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALC 660 Query: 661 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN Sbjct: 661 LDLLSLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLN 720 Query: 721 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD Sbjct: 721 WLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHD 780 Query: 781 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR Sbjct: 781 SIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHR 840 Query: 841 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC Sbjct: 841 VAAAETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYC 900 Query: 901 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTV-LEGDNMETPVTLINFWPVD 959 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQ + E D ++ P+ Sbjct: 901 TPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQNLQAEYDRLKQQHEHKGLSPLP 960 Query: 960 SAP---ASSPQLSHD 971 S P +SPQ D Sbjct: 961 SPPEMMPTSPQSPRD 975 Score = 332 bits (851), Expect = 1e-90 Identities = 167/168 (99%), Positives = 168/168 (100%) Query: 1058 RNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQ 1117 +NLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQ Sbjct: 938 QNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQ 997 Query: 1118 ILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTS 1177 ILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTS Sbjct: 998 ILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTS 1057 Query: 1178 DSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM 1225 DSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM Sbjct: 1058 DSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM 1105 >gi|110611228 utrophin [Homo sapiens] Length = 3433 Score = 1483 bits (3839), Expect = 0.0 Identities = 733/1215 (60%), Positives = 933/1215 (76%), Gaps = 11/1215 (0%) Query: 8 EVPALADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQL 67 E+ AD ++ TEL DWL L+DQ++KS V VGD+E+IN+ + + K T DLEQR PQL Sbjct: 2224 EISIPADLDKTITELADWLVLIDQMLKSNIVTVGDVEEINKTVSRMKITKADLEQRHPQL 2283 Query: 68 EELITAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLE 127 + + T AQNLKNK S+ + RT IT+++ER++NQWD Q ++ R+QQL +M+ DS QW + Sbjct: 2284 DYVFTLAQNLKNKASSSDMRTAITEKLERVKNQWDGTQHGVELRQQQLEDMIIDSLQWDD 2343 Query: 128 AKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKL 187 +EE E+++ + A+L ++ D + K+I++ + L ++L V +++ KL Sbjct: 2344 HREETEELMRKYEARLYILQQARR--DPLTKQISDNQILLQELGPGDGIVMAFDNVLQKL 2401 Query: 188 LRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTE 247 L +Y +DDTR V TE + SW ++ + +++R+ ALE R +Q DLE FL W+ E Sbjct: 2402 LEEYGSDDTRNVKETTEYLKTSWINLKQSIADRQNALEAEWRTVQASRRDLENFLKWIQE 2461 Query: 248 AETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLE 307 AETT NVL DA+ +E L+DS +EL +Q QD+Q EI+AH D++ ++D N QK++++L Sbjct: 2462 AETTVNVLVDASHRENALQDSILARELKQQMQDIQAEIDAHNDIFKSIDGNRQKMVKALG 2521 Query: 308 GSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDE 367 S++A +LQ RLD+MN +W++L+ KS +IR+HLEAS+++W RL +SL+EL+ WL +KD+E Sbjct: 2522 NSEEATMLQHRLDDMNQRWNDLKAKSASIRAHLEASAEKWNRLLMSLEELIKWLNMKDEE 2581 Query: 368 LSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLE---KL 424 L +Q PIGGD PA+Q Q D +A +RELK KE +++ ++ R+FL +QP+E E + Sbjct: 2582 LKKQMPIGGDVPALQLQYDHCKALRRELKEKEYSVLNAVDQARVFLADQPIEAPEEPRRN 2641 Query: 425 YQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATD 484 Q EL PEERAQ + + +RKQ+ EV +WE LN +++WQ+++D+ LE+L++LQ A D Sbjct: 2642 LQSKTELTPEERAQKIAKAMRKQSSEVKEKWESLNAVTSNWQKQVDKALEKLRDLQGAMD 2701 Query: 485 ELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTT 544 +LD +++AE ++ W+PVGDLLIDSLQDH+EK+ A R EIAP+ V VNDL+ QL+ Sbjct: 2702 DLDADMKEAESVRNGWKPVGDLLIDSLQDHIEKIMAFREEIAPINFKVKTVNDLSSQLSP 2761 Query: 545 LGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGPWERA 604 L + S L+DLN RWKLLQV+V+DR++QL EAHRDFGP+SQHFLSTSVQ PW+R+ Sbjct: 2762 LDLHPSLKMSRQLDDLNMRWKLLQVSVDDRLKQLQEAHRDFGPSSQHFLSTSVQLPWQRS 2821 Query: 605 ISPNKVPYYINHETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLL 664 IS NKVPYYINH+TQTTCWDHPKMTEL+QSLADLNNVRFSAYRTA+K+RRLQKALCLDLL Sbjct: 2822 ISHNKVPYYINHQTQTTCWDHPKMTELFQSLADLNNVRFSAYRTAIKIRRLQKALCLDLL 2881 Query: 665 SLSAACDALDQHNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLN 724 LS + QH L QNDQ + + +INCLTT YD LEQ H +LVNVPLCVDMCLNWLLN Sbjct: 2882 ELSTTNEIFKQHKLNQNDQLLSVPDVINCLTTTYDGLEQMHKDLVNVPLCVDMCLNWLLN 2941 Query: 725 VYDTGRTGRIRVLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQI 784 VYDTGRTG+IRV S K G++SL K LE+KYRYLFK+VA T CDQR+LGLLLHD+IQI Sbjct: 2942 VYDTGRTGKIRVQSLKIGLMSLSKGLLEEKYRYLFKEVAGPTEMCDQRQLGLLLHDAIQI 3001 Query: 785 PRQLGEVASFGGSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAA 844 PRQLGEVA+FGGSNIEPSVRSCFQ NNKPEI F+DWM LEPQSMVWLPVLHRVAAA Sbjct: 3002 PRQLGEVAAFGGSNIEPSVRSCFQQNNNKPEISVKEFIDWMHLEPQSMVWLPVLHRVAAA 3061 Query: 845 ETAKHQAKCNICKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTT 904 ETAKHQAKCNICKECPI+GFRYRSLKHFNYD+CQSCFFSGR AKGHK+HYPMVEYC PTT Sbjct: 3062 ETAKHQAKCNICKECPIVGFRYRSLKHFNYDVCQSCFFSGRTAKGHKLHYPMVEYCIPTT 3121 Query: 905 SGEDVRDFAKVLKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPAS 964 SGEDVRDF KVLKNKFR+K+YFAKHPR+GYLPVQTVLEGDN+ETP+TLI+ WP P+ Sbjct: 3122 SGEDVRDFTKVLKNKFRSKKYFAKHPRLGYLPVQTVLEGDNLETPITLISMWPEHYDPSQ 3181 Query: 965 SPQLSHDDTHSRIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSP 1024 SPQL HDDTHSRIE YA+RLA+ME +NGS+L DS S S++DEH LIQ YCQ+L +SP Sbjct: 3182 SPQLFHDDTHSRIEQYATRLAQMERTNGSFLTDSSSTTGSVEDEHALIQQYCQTLGGESP 3241 Query: 1025 LSQPRSPAQILISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPE 1084 +SQP+SPAQIL S+E EERGELERI+ADLEEE RNLQ EY++LK QH +GL P+ SPPE Sbjct: 3242 VSQPQSPAQILKSVEREERGELERIIADLEEEQRNLQVEYEQLKDQHLRRGL-PVGSPPE 3300 Query: 1085 MMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEA 1144 + + + D+ELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQP++++ Sbjct: 3301 SIISPHHTSEDSELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPESDS 3360 Query: 1145 KVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLN 1204 ++NG SP S Q S S + G Q + G EDLL+PP DTST L EVMEQ++ Sbjct: 3361 RINGV---SPWASPQHSALSYSLDPDASGPQFHQAAG-EDLLAPPHDTSTDLTEVMEQIH 3416 Query: 1205 NSFPSSRGRNTPGKP 1219 ++FPS N P +P Sbjct: 3417 STFPSC-CPNVPSRP 3430 Score = 89.4 bits (220), Expect = 2e-17 Identities = 117/589 (19%), Positives = 260/589 (44%), Gaps = 68/589 (11%) Query: 7 LEVPALADFNRAWTELTDWLSLLDQVIKSQRVM-VGDLEDINEMIIKQKATMQDLEQRRP 65 +++ A F+ EL +W+ I++ + ++D +EM K KA ++ +R P Sbjct: 684 VDIEAKKKFDAISAELLNWILKWKTAIQTTEIKEYMKMQDTSEMKKKLKALEKEQRERIP 743 Query: 66 QLEELITAAQNLKNKTSNQEARTI-ITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQ 124 + +EL Q L + + T I + +E++ ++W V +HL++ +++ ++ +D Sbjct: 744 RADELNQTGQILVEQMGKEGLPTEEIKNVLEKVSSEWKNVSQHLEDLERKI-QLQEDINA 802 Query: 125 WLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAK----DLRQWQTNVDVA 180 + + +E E+V+ E W + ++ ++ + K + +L +++A Sbjct: 803 YFKQLDELEKVIKTK----EEWVKHTSISESSRQSLPSLKDSCQRELTNLLGLHPKIEMA 858 Query: 181 NDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALE------------ETH 228 L+ SA D V ++ ++++ + V +R+ LE ET Sbjct: 859 RASCSALMSQPSAPDF--VQRGFDSFLGRYQAVQEAVEDRQQHLENELKGQPGHAYLETL 916 Query: 229 RLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAH 288 + L+ D E +A+ + NVL D + E+ L++ K + E++ E Sbjct: 917 KTLKDVLNDSEN------KAQVSLNVLNDLAKVEKALQEKKTLDEIL----------ENQ 960 Query: 289 TDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELR---KKSLNIRSHLEASSD 345 H L E ++ + +++ D L ++ D++ KW++L+ K L++ + + Sbjct: 961 KPALHKLAEETKALEKNVH-PDVEKLYKQEFDDVQGKWNKLKVLVSKDLHLLEEIALTLR 1019 Query: 346 QWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMST 405 ++ +++ W+ D L +Q GD +Q+Q D AF E++T E + Sbjct: 1020 AFEADSTVIEK---WMDGVKDFLMKQQAAQGDDAGLQRQLDQCSAFVNEIETIES-SLKN 1075 Query: 406 LETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADW 465 ++ + L P+ G+ K + + R + + + +++ + Q ++ EK +A+ Sbjct: 1076 MKEIETNLRSGPVAGI-KTWVQTRLGDYQTQLEKLSKEIATQKSRLSESQEK----AANL 1130 Query: 466 QRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEI 525 ++ + E E + + +E E D + + E ++ + + + D LQ + +VK L+ I Sbjct: 1131 KKDLAEMQEWMTQAEEEYLERDFEYKSPEELESAVEEMKRAKEDVLQKEV-RVKILKDNI 1189 Query: 526 APLKENVSHVNDLARQLTT-LGIQLSPYNL---------STLEDLNTRW 564 L + V ++LT+ L + L Y L TLE++ + W Sbjct: 1190 KLL---AAKVPSGGQELTSELNVVLENYQLLCNRIRGKCHTLEEVWSCW 1235 Score = 86.3 bits (212), Expect = 2e-16 Identities = 116/614 (18%), Positives = 250/614 (40%), Gaps = 71/614 (11%) Query: 12 LADFNRAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELI 71 L + A E+ WL + + Q + D+E++ + +A M +L + + ++ Sbjct: 311 LDSYQIALEEVLTWLLSAEDTFQEQDDISDDVEEVKDQFATHEAFMMELTAHQSSVGSVL 370 Query: 72 TAAQNLKNK-TSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQ------ 124 A L + T + E I +++ + +W+ ++ +R+ +L+++L + + Sbjct: 371 QAGNQLITQGTLSDEEEFEIQEQMTLLNARWEALRVESMDRQSRLHDVLMELQKKQLQQL 430 Query: 125 --WLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVAND 182 WL EE Q K+E+ V ++QK + E K L DL Q V+ Sbjct: 431 SAWLTLTEERIQ-------KMETCPLDD-DVKSLQKLLEEHKSLQSDLEAEQVKVNSLTH 482 Query: 183 LALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFL 242 + + + + T + + + W ++ + ER L+E + L Q+ + Sbjct: 483 MVVIVDENSGESATAILEDQLQKLGERWTAVCRWTEERWNRLQEINILWQELLEEQCLLK 542 Query: 243 AWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKI 302 AWLTE E N +Q + K D K + +++ L+ ++E L E Q + Sbjct: 543 AWLTEKEEALNKVQTSNFK-----DQKELSVSVRRLAILKEDMEMKRQTLDQLSEIGQDV 597 Query: 303 LRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQ 362 + L+ S + + + + +W L ++ + + + + + + ++LL ++ Sbjct: 598 GQLLDNSKASKKINSDSEELTQRWDSLVQRLEDSSNQVTQAVAKLGMSQIPQKDLLETVR 657 Query: 363 LKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTL---------------- 406 +++ +++++ P K+ +H E K K I + L Sbjct: 658 VREQAITKKSKQELPPPPPPKKRQIH--VDIEAKKKFDAISAELLNWILKWKTAIQTTEI 715 Query: 407 -ETVRIFLTEQPLEGLEKLYQEPRELPPEERAQN---------------VTRLLRKQAEE 450 E +++ T + + L+ L +E RE P N T ++ E+ Sbjct: 716 KEYMKMQDTSEMKKKLKALEKEQRERIPRADELNQTGQILVEQMGKEGLPTEEIKNVLEK 775 Query: 451 VNTEWEKLNLHSADWQRK------IDETLERLQELQEATDELDLKLRQAEVIKGSWQPVG 504 V++EW+ ++ H D +RK I+ ++L EL++ + ++ + + S Q + Sbjct: 776 VSSEWKNVSQHLEDLERKIQLQEDINAYFKQLDELEKVIKTKEEWVKHTSISESSRQSLP 835 Query: 505 DLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRW 564 L DS Q L + L +I + + S + +++ +Q + R+ Sbjct: 836 SLK-DSCQRELTNLLGLHPKIEMARASCSAL--MSQPSAPDFVQRG------FDSFLGRY 886 Query: 565 KLLQVAVEDRVRQL 578 + +Q AVEDR + L Sbjct: 887 QAVQEAVEDRQQHL 900 Score = 70.9 bits (172), Expect = 7e-12 Identities = 80/381 (20%), Positives = 155/381 (40%), Gaps = 47/381 (12%) Query: 218 SEREAALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQ 277 +E + + E L + + LE+ L WL AE T D + +D + VK+ Sbjct: 298 AETPSTVTEVDMDLDSYQIALEEVLTWLLSAEDTFQEQDDIS------DDVEEVKDQFAT 351 Query: 278 WQDLQGEIEAH-TDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNI 336 + E+ AH + V L +Q I + ++ +Q ++ +N +W LR +S++ Sbjct: 352 HEAFMMELTAHQSSVGSVLQAGNQLITQGTLSDEEEFEIQEQMTLLNARWEALRVESMDR 411 Query: 337 RSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQ--APIGGDFPAVQKQNDVHRAFKRE 394 +S L + ++ L Q+L WL L ++ + + P+ D ++QK + H++ + + Sbjct: 412 QSRLHDVLMELQKKQL--QQLSAWLTLTEERIQKMETCPLDDDVKSLQKLLEEHKSLQSD 469 Query: 395 LKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTE 454 L+ ++ + S V I E ++ T +L Q +++ Sbjct: 470 LEAEQVKVNSLTHMVVIV--------------------DENSGESATAILEDQLQKLGER 509 Query: 455 WEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDH 514 W + + + ++ E QEL E L L + E + + + + +D Sbjct: 510 WTAVCRWTEERWNRLQEINILWQELLEEQCLLKAWLTEKE------EALNKVQTSNFKDQ 563 Query: 515 LEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQL---------SPYNLSTLEDLNTRWK 565 E ++R +A LKE++ QL+ +G + S S E+L RW Sbjct: 564 KELSVSVR-RLAILKEDMEMKRQTLDQLSEIGQDVGQLLDNSKASKKINSDSEELTQRWD 622 Query: 566 LLQVAVEDRVRQLHEAHRDFG 586 L +ED Q+ +A G Sbjct: 623 SLVQRLEDSSNQVTQAVAKLG 643 Score = 59.7 bits (143), Expect = 2e-08 Identities = 114/635 (17%), Positives = 254/635 (40%), Gaps = 79/635 (12%) Query: 3 SSLMLEVPALADFNRAWTELTDWLSLLDQVIKSQR--------------VMVGDLE---- 44 SS L P LA+ NR + +++ + +I + V DLE Sbjct: 1721 SSRELVEPKLAELNRNFEKVSQHIKSAKLLIAQEPLYQCLVTTETFETGVPFSDLEKLEN 1780 Query: 45 DINEMI------IKQKATMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQ 98 DI M+ ++ + +++ Q+EE++ + + ++ + I ++ + Sbjct: 1781 DIENMLKFVEKHLESSDEDEKMDEESAQIEEVLQRGEEMLHQPMEDNKKEKIRLQLLLLH 1840 Query: 99 NQWDEVQE-HLQNRRQ-QLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAI 156 ++++++ +Q R+ QL ++ S + E ++L +E P AI Sbjct: 1841 TRYNKIKAIPIQQRKMGQLASGIRSSLLPTDYLVEINKIL-LCMDDVELSLNVPELNTAI 1899 Query: 157 QKKIT----ETKQLAKDLRQWQTNVDVANDLALKLLRDYSADDTRKVHMITENINASWRS 212 + + K + L + + V ++ ++ + S + ++ +NA W Sbjct: 1900 YEDFSFQEDSLKNIKDQLDKLGEQIAVIHEKQPDVILEASGPEAIQIRDTLTQLNAKWDR 1959 Query: 213 IHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVK 272 I++ S+R+ + +QF DL W+TEAE +L D L+ ++ Sbjct: 1960 INRMYSDRKGCFDRAMEEWRQFHCDLNDLTQWITEAE---ELLVDTCAPGGSLD----LE 2012 Query: 273 ELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKK 332 + Q+L+ I +H + L+ I++ L +D + L+ +L +N +W + + Sbjct: 2013 KARIHQQELEVGISSHQPSFAALNRTGDGIVQKLSQADGS-FLKEKLAGLNQRWDAIVAE 2071 Query: 333 SLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQA--PIGGDFPAVQ---KQNDV 387 + + L+ S Q + L E++ WL + + +++ +G + ++ ++ +V Sbjct: 2072 VKDRQPRLKGESKQVMKYRHQLDEIICWLTKAEHAMQKRSTTELGENLQELRDLTQEMEV 2131 Query: 388 HRAFKRELKTKEPVIMS--------------TLETVRIF---LTEQPLEGLEKLYQEPRE 430 H + L E ++S +L TV + + + L++ QEP Sbjct: 2132 HAEKLKWLNRTELEMLSDKSLSLPERDKISESLRTVNMTWNKICREVPTTLKECIQEPSS 2191 Query: 431 LPPEERA--QNVTR-LLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELD 487 + A NV + +L A ++ + + + S +D+T+ L + D++ Sbjct: 2192 VSQTRIAAHPNVQKVVLVSSASDIPVQSHRTSEISI--PADLDKTITELADWLVLIDQM- 2248 Query: 488 LKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGI 547 +K + VGD ++ + + ++K + ++ + +V LA+ L Sbjct: 2249 --------LKSNIVTVGD--VEEINKTVSRMKITKADLEQRHPQLDYVFTLAQNLKNKAS 2298 Query: 548 QLSPYNLST--LEDLNTRWKLLQVAVEDRVRQLHE 580 T LE + +W Q VE R +QL + Sbjct: 2299 SSDMRTAITEKLERVKNQWDGTQHGVELRQQQLED 2333 Score = 59.7 bits (143), Expect = 2e-08 Identities = 100/541 (18%), Positives = 198/541 (36%), Gaps = 92/541 (17%) Query: 90 ITDRIERIQNQWDEVQEHLQNRR----------QQLNEMLKDSTQWLEAKEEAEQVLGQA 139 I D + ++ +WD + +R+ +Q + L D TQW+ EAE++L Sbjct: 1946 IRDTLTQLNAKWDRINRMYSDRKGCFDRAMEEWRQFHCDLNDLTQWIT---EAEELLVDT 2002 Query: 140 RAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDYSADDTRKV 199 A S ++K ++L + Q + N +++ S D + Sbjct: 2003 CAPGGSLD--------LEKARIHQQELEVGISSHQPSFAALNRTGDGIVQKLSQADGSFL 2054 Query: 200 HMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDAT 259 +N W +I V +R+ L+ + + ++ L++ + WLT+AE A Sbjct: 2055 KEKLAGLNQRWDAIVAEVKDRQPRLKGESKQVMKYRHQLDEIICWLTKAE-------HAM 2107 Query: 260 RKERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRR- 318 +K E + ++EL +DL E+E H + L+ ++L SD ++ L R Sbjct: 2108 QKRSTTELGENLQEL----RDLTQEMEVHAEKLKWLNRTELEML-----SDKSLSLPERD 2158 Query: 319 -----LDNMNFKWSELRKK------------------------------------SLNIR 337 L +N W+++ ++ + ++ Sbjct: 2159 KISESLRTVNMTWNKICREVPTTLKECIQEPSSVSQTRIAAHPNVQKVVLVSSASDIPVQ 2218 Query: 338 SHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKT 397 SH + L ++ EL WL L D L GD + K + K +L+ Sbjct: 2219 SHRTSEISIPADLDKTITELADWLVLIDQMLKSNIVTVGDVEEINKTVSRMKITKADLEQ 2278 Query: 398 KEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPE--ERAQNVTRLLRKQAEEV---N 452 + P + + + + E E + Q+ L ++Q E++ + Sbjct: 2279 RHPQLDYVFTLAQNLKNKASSSDMRTAITEKLERVKNQWDGTQHGVELRQQQLEDMIIDS 2338 Query: 453 TEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQ 512 +W+ + + RK + L LQ Q D L ++ +++ P GD ++ + Sbjct: 2339 LQWDDHREETEELMRKYEARLYILQ--QARRDPLTKQISDNQILLQELGP-GDGIVMAFD 2395 Query: 513 DHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVE 572 + L+K+ G ++ +V + L T I L L W+ +Q + Sbjct: 2396 NVLQKLLEEYG-----SDDTRNVKETTEYLKTSWINLKQSIADRQNALEAEWRTVQASRR 2450 Query: 573 D 573 D Sbjct: 2451 D 2451 Score = 54.7 bits (130), Expect = 5e-07 Identities = 95/519 (18%), Positives = 212/519 (40%), Gaps = 71/519 (13%) Query: 17 RAWTELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITA--- 73 R WTE DW + L + G++ I+ + + +A + ++E++ +E I Sbjct: 1637 RTWTE--DWCNTLMNHQNQLEIFDGNVAHISTWLYQAEALLDEIEKKPTSKQEEIVKRLV 1694 Query: 74 ---------AQNLKNKT------SNQEARTIITDRIERIQNQWDEVQEHLQNRR-----Q 113 +N++++ +R ++ ++ + +++V +H+++ + + Sbjct: 1695 SELDDANLQVENVRDQALILMNARGSSSRELVEPKLAELNRNFEKVSQHIKSAKLLIAQE 1754 Query: 114 QLNEMLKDSTQW--------LEAKE-EAEQVLGQARAKLESWKEGPYTVDAIQKKITETK 164 L + L + + LE E + E +L LES E +D +I E Sbjct: 1755 PLYQCLVTTETFETGVPFSDLEKLENDIENMLKFVEKHLESSDEDE-KMDEESAQIEEVL 1813 Query: 165 QLAKDLRQWQTNVDVANDLALKLLRDYSADDTRKVHMITENINASWRSIHKRVSEREAAL 224 Q +++ + + L+LL ++ + K I + R + + S ++L Sbjct: 1814 QRGEEMLHQPMEDNKKEKIRLQLLLLHTRYNKIKAIPIQQ------RKMGQLASGIRSSL 1867 Query: 225 EETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLLEDSKGVKELMKQWQDLQGE 284 T L++ + K L + + E + NV + T + ED ++ +K +D + Sbjct: 1868 LPTDYLVE-----INKILLCMDDVELSLNVPELNTA---IYEDFSFQEDSLKNIKDQLDK 1919 Query: 285 IEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASS 344 + V H E ++ G + A+ ++ L +N KW + + + + + + Sbjct: 1920 LGEQIAVIH---EKQPDVILEASGPE-AIQIRDTLTQLNAKWDRINRMYSDRKGCFDRAM 1975 Query: 345 DQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAV-----QKQNDV-----HRAFKRE 394 ++W++ H L +L W+ ++ L GG Q++ +V +F Sbjct: 1976 EEWRQFHCDLNDLTQWITEAEELLVDTCAPGGSLDLEKARIHQQELEVGISSHQPSFAAL 2035 Query: 395 LKTKEPVIMSTLETVRIFLTEQPLEGL----EKLYQEPRELPPEERAQNVTRL-LRKQAE 449 +T + ++ + FL E+ L GL + + E ++ P + ++ + R Q + Sbjct: 2036 NRTGDGIVQKLSQADGSFLKEK-LAGLNQRWDAIVAEVKDRQPRLKGESKQVMKYRHQLD 2094 Query: 450 EVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDL 488 E+ W H+ +R E E LQEL++ T E+++ Sbjct: 2095 EIIC-WLTKAEHAMQ-KRSTTELGENLQELRDLTQEMEV 2131 Score = 51.6 bits (122), Expect = 5e-06 Identities = 106/574 (18%), Positives = 231/574 (40%), Gaps = 67/574 (11%) Query: 22 LTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNKT 81 L++WLS + + + G L D++ I K ++DLE+R+ L + ++ L+N Sbjct: 1556 LSEWLSATETELVQKSTSEGLLGDLDTEISWAKNVLKDLEKRKADLNTITESSAALQNLI 1615 Query: 82 SNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARA 141 E I+ +R+ + W V+ ++ N ++ Q ++ A Sbjct: 1616 EGSE--PILEERLCVLNAGWSRVRTWTED---WCNTLMNHQNQL--------EIFDGNVA 1662 Query: 142 KLESW-KEGPYTVDAIQKKITE-----TKQLAKDLRQWQTNVDVANDLALKLLRDYSADD 195 + +W + +D I+KK T K+L +L V+ D AL L+ + Sbjct: 1663 HISTWLYQAEALLDEIEKKPTSKQEEIVKRLVSELDDANLQVENVRDQALILMNARGSSS 1722 Query: 196 TRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWL--TEAETTAN 253 V +N ++ + + + + A L L Q + E F + ++ E N Sbjct: 1723 RELVEPKLAELNRNFEKVSQHI--KSAKLLIAQEPLYQCLVTTETFETGVPFSDLEKLEN 1780 Query: 254 VLQDATR-KERLLEDSKGVKELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDA 312 +++ + E+ LE S +++ ++ ++ ++ ++ H E+++K L+ Sbjct: 1781 DIENMLKFVEKHLESSDEDEKMDEESAQIEEVLQRGEEMLHQPMEDNKKEKIRLQ----L 1836 Query: 313 VLLQRRLDNMN---FKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELS 369 +LL R + + + ++ + + IRS L +D ++ L L + D ELS Sbjct: 1837 LLLHTRYNKIKAIPIQQRKMGQLASGIRSSL-LPTDYLVEINKIL------LCMDDVELS 1889 Query: 370 RQAPIGGDFPAVQKQNDVHRAF---KRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQ 426 P + ++ F + LK + + E + + +QP LE Sbjct: 1890 LNVP--------ELNTAIYEDFSFQEDSLKNIKDQLDKLGEQIAVIHEKQPDVILEASGP 1941 Query: 427 EPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDEL 486 E + +R ++N +W+++N +D + D +E ++ ++L Sbjct: 1942 EAIQ-------------IRDTLTQLNAKWDRINRMYSDRKGCFDRAMEEWRQFHCDLNDL 1988 Query: 487 DLKLRQA-EVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVND-LARQLTT 544 + +A E++ + P G L ++ + H ++++ P ++ D + ++L+ Sbjct: 1989 TQWITEAEELLVDTCAPGGSLDLEKARIHQQELEVGISSHQPSFAALNRTGDGIVQKLSQ 2048 Query: 545 LGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQL 578 + L LN RW + V+DR +L Sbjct: 2049 AD---GSFLKEKLAGLNQRWDAIVAEVKDRQPRL 2079 Score = 47.0 bits (110), Expect = 1e-04 Identities = 108/599 (18%), Positives = 232/599 (38%), Gaps = 104/599 (17%) Query: 19 WTEL-------TDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELI 71 W EL T WL+ L++ +KS V+ + +NE + ++ ++ R Q+ EL Sbjct: 1235 WIELLHYLDLETTWLNTLEERMKSTEVLPEKTDAVNEALESLESVLRHPADNRTQIREL- 1293 Query: 72 TAAQNLKNKTSNQEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEE 131 Q L + + II++++E ++++++ ++++ L + L Q L ++ Sbjct: 1294 --GQTLIDGGILDD---IISEKLEAFNSRYEDLSHLAESKQISLEKQL----QVLRETDQ 1344 Query: 132 AEQVLGQARAKLESWKEGPYTVDAIQKKITETKQLAKDLRQWQTNVDVANDLALKLLRDY 191 QVL ++ +L+ + Y D I + Q+ ++ ++ Q + A++L L+ LR Sbjct: 1345 MLQVLQESLGELDK-QLTTYLTDRI-----DAFQVPQEAQKIQAEIS-AHELTLEELRR- 1396 Query: 192 SADDTRKVHMITENINASWRSIHKRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAETT 251 +M ++ + S R + + ++ R L++ + F + Sbjct: 1397 --------NMRSQPLT----SPESRTARGGSQMDVLQRKLREVSTKFQLF-------QKP 1437 Query: 252 ANVLQDATRKERLLEDSKGVKELMKQWQDLQGEIEAHTD----VYHNLDENSQKI----- 302 AN Q +R+L+ K ++ I+ H D +Y L E ++ Sbjct: 1438 ANFEQRMLDCKRVLDGVKAELHVLDVKDVDPDVIQTHLDKCMKLYKTLSEVKLEVETVIK 1497 Query: 303 ----LRSLEGSDDAVLLQRRLDNMNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELL 358 + + +D+ + +L ++ +++L + + LE +S +++ L Sbjct: 1498 TGRHIVQKQQTDNPKGMDEQLTSLKVLYNDLGAQVTEGKQDLERASQLARKMKKEAASLS 1557 Query: 359 VWLQLKDDELSRQAPIGGDFPAVQKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPL 418 WL + EL +++ G + + + ++L+ ++ + + E+ + + Sbjct: 1558 EWLSATETELVQKSTSEGLLGDLDTEISWAKNVLKDLEKRKADLNTITESSAAL--QNLI 1615 Query: 419 EGLEKLYQEPRELPPEERAQNVTRLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQE 478 EG E + +E RL +N W ++ + DW + +L+ Sbjct: 1616 EGSEPILEE--------------RLC-----VLNAGWSRVRTWTEDWCNTLMNHQNQLEI 1656 Query: 479 LQEATDELDLKLRQAEVIKGSWQPVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDL 538 + L QAE +L D +EK P + V L Sbjct: 1657 FDGNVAHISTWLYQAE---------------ALLDEIEK--------KPTSKQEEIVKRL 1693 Query: 539 ARQLTTLGIQLSPYNLSTLEDLNTRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSV 597 +L +Q+ L +N R + VE + L E +R+F SQH S + Sbjct: 1694 VSELDDANLQVENVRDQALILMNARGSSSRELVEPK---LAELNRNFEKVSQHIKSAKL 1749 Score = 35.4 bits (80), Expect = 0.34 Identities = 33/136 (24%), Positives = 61/136 (44%), Gaps = 4/136 (2%) Query: 1038 LESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAE 1097 ++ ++ E+++ L LE+E R D L Q + + E +PT + Sbjct: 719 MKMQDTSEMKKKLKALEKEQRERIPRADELNQTGQ---ILVEQMGKEGLPTEEIKNVLEK 775 Query: 1098 LIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTS 1157 + +E K + QH LE ++Q+ ED N + QL L ++++ + K + SS + Sbjct: 776 VSSEWKNVSQHLEDLERKIQLQEDINAYFK-QLDELEKVIKTKEEWVKHTSISESSRQSL 834 Query: 1158 LQRSDSSQPMLLRVVG 1173 DS Q L ++G Sbjct: 835 PSLKDSCQRELTNLLG 850 >gi|5032297 dystrophin Dp71 isoform [Homo sapiens] Length = 617 Score = 1240 bits (3208), Expect = 0.0 Identities = 610/610 (100%), Positives = 610/610 (100%) Query: 616 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 675 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ Sbjct: 8 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 67 Query: 676 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 735 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR Sbjct: 68 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 127 Query: 736 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 795 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG Sbjct: 128 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 187 Query: 796 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 855 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI Sbjct: 188 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 247 Query: 856 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 915 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV Sbjct: 248 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 307 Query: 916 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHS 975 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHS Sbjct: 308 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHS 367 Query: 976 RIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQIL 1035 RIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQIL Sbjct: 368 RIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQIL 427 Query: 1036 ISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRD 1095 ISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRD Sbjct: 428 ISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRD 487 Query: 1096 AELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPS 1155 AELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPS Sbjct: 488 AELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPS 547 Query: 1156 TSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNT 1215 TSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNT Sbjct: 548 TSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNT 607 Query: 1216 PGKPMREDTM 1225 PGKPMREDTM Sbjct: 608 PGKPMREDTM 617 >gi|5032299 dystrophin Dp71b isoform [Homo sapiens] Length = 635 Score = 1214 bits (3142), Expect = 0.0 Identities = 598/599 (99%), Positives = 598/599 (99%) Query: 616 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 675 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ Sbjct: 8 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 67 Query: 676 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 735 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR Sbjct: 68 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 127 Query: 736 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 795 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG Sbjct: 128 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 187 Query: 796 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 855 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI Sbjct: 188 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 247 Query: 856 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 915 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV Sbjct: 248 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 307 Query: 916 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHS 975 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHS Sbjct: 308 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHS 367 Query: 976 RIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQIL 1035 RIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQIL Sbjct: 368 RIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQIL 427 Query: 1036 ISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRD 1095 ISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRD Sbjct: 428 ISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRD 487 Query: 1096 AELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPS 1155 AELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPS Sbjct: 488 AELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPS 547 Query: 1156 TSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRN 1214 TSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRG N Sbjct: 548 TSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHN 606 >gi|5032301 dystrophin Dp71a isoform [Homo sapiens] Length = 604 Score = 1203 bits (3112), Expect = 0.0 Identities = 597/610 (97%), Positives = 597/610 (97%), Gaps = 13/610 (2%) Query: 616 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 675 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ Sbjct: 8 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 67 Query: 676 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 735 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR Sbjct: 68 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 127 Query: 736 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 795 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG Sbjct: 128 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 187 Query: 796 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 855 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI Sbjct: 188 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 247 Query: 856 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 915 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV Sbjct: 248 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 307 Query: 916 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHS 975 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET PASSPQLSHDDTHS Sbjct: 308 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET-------------PASSPQLSHDDTHS 354 Query: 976 RIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQIL 1035 RIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQIL Sbjct: 355 RIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQIL 414 Query: 1036 ISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRD 1095 ISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRD Sbjct: 415 ISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRD 474 Query: 1096 AELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPS 1155 AELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPS Sbjct: 475 AELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPS 534 Query: 1156 TSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNT 1215 TSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNT Sbjct: 535 TSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNT 594 Query: 1216 PGKPMREDTM 1225 PGKPMREDTM Sbjct: 595 PGKPMREDTM 604 >gi|5032303 dystrophin Dp71ab isoform [Homo sapiens] Length = 622 Score = 1177 bits (3046), Expect = 0.0 Identities = 585/599 (97%), Positives = 585/599 (97%), Gaps = 13/599 (2%) Query: 616 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 675 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ Sbjct: 8 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 67 Query: 676 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 735 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR Sbjct: 68 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 127 Query: 736 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 795 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG Sbjct: 128 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 187 Query: 796 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 855 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI Sbjct: 188 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 247 Query: 856 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 915 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV Sbjct: 248 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 307 Query: 916 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHS 975 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET PASSPQLSHDDTHS Sbjct: 308 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET-------------PASSPQLSHDDTHS 354 Query: 976 RIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQIL 1035 RIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQIL Sbjct: 355 RIEHYASRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQIL 414 Query: 1036 ISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRD 1095 ISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRD Sbjct: 415 ISLESEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRD 474 Query: 1096 AELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPS 1155 AELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPS Sbjct: 475 AELIAEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPS 534 Query: 1156 TSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRN 1214 TSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRG N Sbjct: 535 TSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGHN 593 >gi|148539558 dystrophin related protein 2 [Homo sapiens] Length = 957 Score = 996 bits (2574), Expect = 0.0 Identities = 494/892 (55%), Positives = 651/892 (72%), Gaps = 27/892 (3%) Query: 322 MNFKWSELRKKSLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQAPIGGDFPAV 381 MN W+E++KKS N+R+ LEA SD +L L LQE++ WL KD+ELS Q P+ GD V Sbjct: 79 MNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDWLSQKDEELSAQLPLQGDVALV 138 Query: 382 QKQNDVHRAFKRELKTKEPVIMSTLETVRIFLTEQPLEGLEKLYQEPRELPPEERAQNVT 441 Q++ + H AF E+K++ P I S LE+ + FL++ P E LE+ + E ++ P++R QN++ Sbjct: 139 QQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQHPFEELEEPHSESKDTSPKQRIQNLS 198 Query: 442 RLLRKQAEEVNTEWEKLNLHSADWQRKIDETLERLQELQEATDELDLKLRQAEVIKGSWQ 501 R + KQA + WEKL D R I+ TLE+L E+Q A +EL L QAE ++ +W+ Sbjct: 199 RFVWKQATVASELWEKLTARCVDQHRHIERTLEQLLEIQGAMEELSTTLSQAEGVRATWE 258 Query: 502 PVGDLLIDSLQDHLEKVKALRGEIAPLKENVSHVNDLARQLTTLGIQLSPYNLSTLEDLN 561 P+GDL IDSL +H++ +K + E +P+K+ V VNDLA QL + LS N LE +N Sbjct: 259 PIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLVNDLAHQLAISDVHLSMENSQALEQIN 318 Query: 562 TRWKLLQVAVEDRVRQLHEAHRDFGPASQHFLSTSVQGPWERAISPNKVPYYINHETQTT 621 RWK LQ +V +R++QL +AHRDFGP SQHFLS+SVQ PWERAISPNKVPYYINH+ QTT Sbjct: 319 VRWKQLQASVSERLKQLQDAHRDFGPGSQHFLSSSVQVPWERAISPNKVPYYINHQAQTT 378 Query: 622 CWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQN 681 CWDHPKMTELYQ+LADLNN++FSAYRTAMKLRR+QKAL LDL++L+ A + ++H+L+ + Sbjct: 379 CWDHPKMTELYQTLADLNNIKFSAYRTAMKLRRVQKALRLDLVTLTTALEIFNEHDLQAS 438 Query: 682 DQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKT 741 + MD++++I+CLT +Y+RLE+E LVNVPLCVDM LNWLLNV+D+GR+G++R LSFKT Sbjct: 439 EHVMDVVEVIHCLTALYERLEEERGILVNVPLCVDMSLNWLLNVFDSGRSGKMRALSFKT 498 Query: 742 GIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEP 801 GI LC +++K +YLF QVA+S CDQR LG+LLH++IQ+PRQLGEVA+FGGSN+EP Sbjct: 499 GIACLCGTEVKEKLQYLFSQVANSGSQCDQRHLGVLLHEAIQVPRQLGEVAAFGGSNVEP 558 Query: 802 SVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNICKECPI 861 SVRSCF+F+ KP IEA+ FL+W+ LEPQSMVWL VLHRV AE KHQ KC+IC++CPI Sbjct: 559 SVRSCFRFSTGKPVIEASQFLEWVNLEPQSMVWLAVLHRVTIAEQVKHQTKCSICRQCPI 618 Query: 862 IGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFR 921 GFRYRSLK FN DICQ+CF +GR +KG+K+HYP++EY TPTTS E++RDFA LKNKFR Sbjct: 619 KGFRYRSLKQFNVDICQTCFLTGRASKGNKLHYPIMEYYTPTTSSENMRDFATTLKNKFR 678 Query: 922 TKRYFAKHPRMGYLPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYA 981 +K YF+KHP+ GYLPVQ+VLE D ET PASSP H DTHSRIEH+A Sbjct: 679 SKHYFSKHPQRGYLPVQSVLEADYSET-------------PASSPMWPHADTHSRIEHFA 725 Query: 982 SRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLS--QPRSPAQILISLE 1039 SRLAEME+ N S+ NDS+SP++SID++ L++H SP++ +P Q S+ Sbjct: 726 SRLAEMESQNCSFFNDSLSPDDSIDEDQYLLRH-------SSPITDREPAFGQQAPCSVA 778 Query: 1040 SEERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELI 1099 +E +GEL++ILA LE+ENR LQ E RLK QHE + PS + + R+ EL+ Sbjct: 779 TESKGELQKILAHLEDENRILQGELRRLKWQHEE--AAEAPSLADGSTEAATDHRNEELL 836 Query: 1100 AEAKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQ 1159 AEA++LRQHK RLE RMQILEDHNKQLESQL RLR+LL QP E+ +G+ SS ++S Q Sbjct: 837 AEARILRQHKSRLETRMQILEDHNKQLESQLQRLRELLLQPPTESDGSGSAGSSLASSPQ 896 Query: 1160 RSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSR 1211 +S+ S P R G T D+ +D+ S QD S LE++ME+L ++FPS R Sbjct: 897 QSEGSHP---REKGQTTPDTEAADDVGSKSQDVSLCLEDIMEKLRHAFPSVR 945 Score = 65.9 bits (159), Expect = 2e-10 Identities = 54/235 (22%), Positives = 101/235 (42%), Gaps = 33/235 (14%) Query: 21 ELTDWLSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRPQLEELITAAQNLKNK 80 E+ DWLS D+ + +Q + GD+ + + A M++++ R P + ++ +AQ ++ Sbjct: 113 EIIDWLSQKDEELSAQLPLQGDVALVQQEKETHAAFMEEVKSRGPYIYSVLESAQAFLSQ 172 Query: 81 TSNQE-----ARTIITDRIERIQN--------------QWDEVQEHLQNRRQQLNEMLKD 121 +E + + T +RIQN W+++ ++ + + L+ Sbjct: 173 HPFEELEEPHSESKDTSPKQRIQNLSRFVWKQATVASELWEKLTARCVDQHRHIERTLEQ 232 Query: 122 STQWLEAKEEAEQVLGQARAKLESWKE-GPYTVDAIQKKITETKQLAKDLRQWQTNVDVA 180 + A EE L QA +W+ G +D++ + I K ++ + V + Sbjct: 233 LLEIQGAMEELSTTLSQAEGVRATWEPIGDLFIDSLPEHIQAIKLFKEEFSPMKDGVKLV 292 Query: 181 NDLALKLLRDYSADDTRKVHMITEN------INASWRSIHKRVSEREAALEETHR 229 NDLA +L VH+ EN IN W+ + VSER L++ HR Sbjct: 293 NDLAHQLA-------ISDVHLSMENSQALEQINVRWKQLQASVSERLKQLQDAHR 340 >gi|5032305 dystrophin Dp40 isoform [Homo sapiens] Length = 340 Score = 693 bits (1789), Expect = 0.0 Identities = 333/333 (100%), Positives = 333/333 (100%) Query: 616 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 675 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ Sbjct: 8 HETQTTCWDHPKMTELYQSLADLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQ 67 Query: 676 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 735 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR Sbjct: 68 HNLKQNDQPMDILQIINCLTTIYDRLEQEHNNLVNVPLCVDMCLNWLLNVYDTGRTGRIR 127 Query: 736 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 795 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG Sbjct: 128 VLSFKTGIISLCKAHLEDKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFG 187 Query: 796 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 855 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI Sbjct: 188 GSNIEPSVRSCFQFANNKPEIEAALFLDWMRLEPQSMVWLPVLHRVAAAETAKHQAKCNI 247 Query: 856 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 915 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV Sbjct: 248 CKECPIIGFRYRSLKHFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKV 307 Query: 916 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET 948 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET Sbjct: 308 LKNKFRTKRYFAKHPRMGYLPVQTVLEGDNMET 340 >gi|42717999 dystrobrevin alpha isoform 2 [Homo sapiens] Length = 686 Score = 212 bits (540), Expect = 2e-54 Identities = 171/590 (28%), Positives = 279/590 (47%), Gaps = 72/590 (12%) Query: 637 DLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQ--PMDILQIINCL 694 DL+ +R S YRTA KLR +QK L L+ + +AL ++ L D +++ ++ L Sbjct: 26 DLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPNTELNVSRLEAVL 85 Query: 695 TTIYDRLEQEH--NNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLE 752 +TI+ +L + + ++V + + LN+LL +D G+I V + K + +LC + Sbjct: 86 STIFYQLNKRMPTTHQIHVEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIM 145 Query: 753 DKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANN 812 DK RY+F ++ S+G R L + +++P + E SFG + E S RSCF + Sbjct: 146 DKLRYIFSMISDSSGVMVYGRYDQFLREVLKLPTAVFEGPSFGYT--EQSARSCF---SQ 200 Query: 813 KPEIEAALFLDWMRLEP--QSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLK 870 + ++ FLD + +P Q +VWLP+LHR+A E H +C+ C ++GFRYR + Sbjct: 201 QKKVTLNGFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQ 260 Query: 871 HFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHP 930 NY +CQ CF+ G H + M EY T+ + L ++ P Sbjct: 261 CHNYQLCQDCFWRGHAGGSHSNQHQMKEY---TSWKSPAKKLTNALSKSLSCAS--SREP 315 Query: 931 RMGYLPVQTVLEGDNMETPVTL---INFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEM 987 P D E P+ L ++ WP + + L S + +R + + Sbjct: 316 LHPMFP-------DQPEKPLNLAHIVDTWPPRPVTSMNDTLFSHSVPSSGSPFITR-SML 367 Query: 988 ENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQP---RSPAQILISLESEERG 1044 E+SN +D+EH LI Y L +S SQP RS I ++++ + Sbjct: 368 ESSN------------RLDEEHRLIARYAARLAAESSSSQPPQQRSAPDISFTIDANK-- 413 Query: 1045 ELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKL 1104 + +++A+LE +NR + E RL+ +HE + P P + PT L+AE +L Sbjct: 414 QQRQLIAELENKNREILQEIQRLRLEHE-QASQPTPEKAQQNPT---------LLAELRL 463 Query: 1105 LRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSS 1164 LRQ K LE RM L++ ++L QL L +LL+ A G+ SSPS ++ R Sbjct: 464 LRQRKDELEQRMSALQESRRELMVQLEGLMKLLKTQGA-----GSPRSSPSHTISR---P 515 Query: 1165 QPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRN 1214 PM +R + ++ + PQD+ TG V + +F S RN Sbjct: 516 IPMPIRSASACSTPT-------HTPQDSLTG---VGGDVQEAFAQSSRRN 555 >gi|42718005 dystrobrevin alpha isoform 1 [Homo sapiens] Length = 743 Score = 206 bits (525), Expect = 8e-53 Identities = 180/629 (28%), Positives = 291/629 (46%), Gaps = 93/629 (14%) Query: 637 DLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQ--PMDILQIINCL 694 DL+ +R S YRTA KLR +QK L L+ + +AL ++ L D +++ ++ L Sbjct: 26 DLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPNTELNVSRLEAVL 85 Query: 695 TTIYDRLEQEH--NNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLE 752 +TI+ +L + + ++V + + LN+LL +D G+I V + K + +LC + Sbjct: 86 STIFYQLNKRMPTTHQIHVEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIM 145 Query: 753 DKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANN 812 DK RY+F ++ S+G R L + +++P + E SFG + E S RSCF + Sbjct: 146 DKLRYIFSMISDSSGVMVYGRYDQFLREVLKLPTAVFEGPSFGYT--EQSARSCF---SQ 200 Query: 813 KPEIEAALFLDWMRLEP--QSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLK 870 + ++ FLD + +P Q +VWLP+LHR+A E H +C+ C ++GFRYR + Sbjct: 201 QKKVTLNGFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQ 260 Query: 871 HFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAK-- 928 NY +CQ CF+ G H + M EY + + AK L N A Sbjct: 261 CHNYQLCQDCFWRGHAGGSHSNQHQMKEYTS-------WKSPAKKLTNALSKSLSCASSR 313 Query: 929 ---HPRMGYLPVQTVLEGDNMET----PVTLIN------FWPVDSAP---ASSPQLSHDD 972 HP P + + ++T PVT +N P +P SSP + Sbjct: 314 EPLHPMFPDQPEKPLNLAHIVDTWPPRPVTSMNDTLFSHSVPSSGSPFITRSSPPKDSEV 373 Query: 973 THSRI-----------------EHYASRLAEMENSNGSYLN-------DSISPNESIDDE 1008 +++ + A RLA+ G Y+N + + +D+E Sbjct: 374 EQNKLLARAAPAFLKGKGIQYSLNVADRLADEHVLIGLYVNMLRNNPSCMLESSNRLDEE 433 Query: 1009 HLLIQHYCQSLNQDSPLSQP---RSPAQILISLESEERGELERILADLEEENRNLQAEYD 1065 H LI Y L +S SQP RS I ++++ + + +++A+LE +NR + E Sbjct: 434 HRLIARYAARLAAESSSSQPPQQRSAPDISFTIDANK--QQRQLIAELENKNREILQEIQ 491 Query: 1066 RLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQ 1125 RL+ +HE + P P + PT L+AE +LLRQ K LE RM L++ ++ Sbjct: 492 RLRLEHE-QASQPTPEKAQQNPT---------LLAELRLLRQRKDELEQRMSALQESRRE 541 Query: 1126 LESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDL 1185 L QL L +LL+ A G+ SSPS ++ R PM +R + ++ + Sbjct: 542 LMVQLEGLMKLLKTQGA-----GSPRSSPSHTISR---PIPMPIRSASACSTPT------ 587 Query: 1186 LSPPQDTSTGLEEVMEQLNNSFPSSRGRN 1214 PQD+ TG V + +F S RN Sbjct: 588 -HTPQDSLTG---VGGDVQEAFAQSSRRN 612 >gi|42717997 dystrobrevin alpha isoform 5 [Homo sapiens] Length = 513 Score = 206 bits (525), Expect = 8e-53 Identities = 152/523 (29%), Positives = 253/523 (48%), Gaps = 54/523 (10%) Query: 637 DLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQ--PMDILQIINCL 694 DL+ +R S YRTA KLR +QK L L+ + +AL ++ L D +++ ++ L Sbjct: 26 DLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPNTELNVSRLEAVL 85 Query: 695 TTIYDRLEQEH--NNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLE 752 +TI+ +L + + ++V + + LN+LL +D G+I V + K + +LC + Sbjct: 86 STIFYQLNKRMPTTHQIHVEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIM 145 Query: 753 DKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANN 812 DK RY+F ++ S+G R L + +++P + E SFG + E S RSCF + Sbjct: 146 DKLRYIFSMISDSSGVMVYGRYDQFLREVLKLPTAVFEGPSFGYT--EQSARSCF---SQ 200 Query: 813 KPEIEAALFLDWMRLEP--QSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLK 870 + ++ FLD + +P Q +VWLP+LHR+A E H +C+ C ++GFRYR + Sbjct: 201 QKKVTLNGFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQ 260 Query: 871 HFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHP 930 NY +CQ CF+ G H + M EY T+ + L ++ P Sbjct: 261 CHNYQLCQDCFWRGHAGGSHSNQHQMKEY---TSWKSPAKKLTNALSKSLSCAS--SREP 315 Query: 931 RMGYLPVQTVLEGDNMETPVTL---INFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEM 987 P D E P+ L ++ WP + + L S + +R + + Sbjct: 316 LHPMFP-------DQPEKPLNLAHIVDTWPPRPVTSMNDTLFSHSVPSSGSPFITR-SML 367 Query: 988 ENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQP---RSPAQILISLESEERG 1044 E+SN +D+EH LI Y L +S SQP RS I ++++ + Sbjct: 368 ESSN------------RLDEEHRLIARYAARLAAESSSSQPPQQRSAPDISFTIDANK-- 413 Query: 1045 ELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKL 1104 + +++A+LE +NR + E RL+ +HE + P P + PT L+AE +L Sbjct: 414 QQRQLIAELENKNREILQEIQRLRLEHE-QASQPTPEKAQQNPT---------LLAELRL 463 Query: 1105 LRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVN 1147 LRQ K LE RM L++ ++L QL L +LL++ + + V+ Sbjct: 464 LRQRKDELEQRMSALQESRRELMVQLEGLMKLLKEEELKQGVS 506 >gi|42718003 dystrobrevin alpha isoform 3 [Homo sapiens] Length = 570 Score = 201 bits (510), Expect = 5e-51 Identities = 161/562 (28%), Positives = 265/562 (47%), Gaps = 75/562 (13%) Query: 637 DLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQ--PMDILQIINCL 694 DL+ +R S YRTA KLR +QK L L+ + +AL ++ L D +++ ++ L Sbjct: 26 DLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPNTELNVSRLEAVL 85 Query: 695 TTIYDRLEQEH--NNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLE 752 +TI+ +L + + ++V + + LN+LL +D G+I V + K + +LC + Sbjct: 86 STIFYQLNKRMPTTHQIHVEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIM 145 Query: 753 DKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANN 812 DK RY+F ++ S+G R L + +++P + E SFG + E S RSCF + Sbjct: 146 DKLRYIFSMISDSSGVMVYGRYDQFLREVLKLPTAVFEGPSFGYT--EQSARSCF---SQ 200 Query: 813 KPEIEAALFLDWMRLEP--QSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLK 870 + ++ FLD + +P Q +VWLP+LHR+A E H +C+ C ++GFRYR + Sbjct: 201 QKKVTLNGFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQ 260 Query: 871 HFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAK-- 928 NY +CQ CF+ G H + M EY + + AK L N A Sbjct: 261 CHNYQLCQDCFWRGHAGGSHSNQHQMKEYTS-------WKSPAKKLTNALSKSLSCASSR 313 Query: 929 ---HPRMGYLPVQTVLEGDNMET----PVTLIN------FWPVDSAP---ASSPQLSHDD 972 HP P + + ++T PVT +N P +P SSP + Sbjct: 314 EPLHPMFPDQPEKPLNLAHIVDTWPPRPVTSMNDTLFSHSVPSSGSPFITRSSPPKDSEV 373 Query: 973 THSRI-----------------EHYASRLAEMENSNGSYLN-------DSISPNESIDDE 1008 +++ + A RLA+ G Y+N + + +D+E Sbjct: 374 EQNKLLARAAPAFLKGKGIQYSLNVADRLADEHVLIGLYVNMLRNNPSCMLESSNRLDEE 433 Query: 1009 HLLIQHYCQSLNQDSPLSQP---RSPAQILISLESEERGELERILADLEEENRNLQAEYD 1065 H LI Y L +S SQP RS I ++++ + + +++A+LE +NR + E Sbjct: 434 HRLIARYAARLAAESSSSQPPQQRSAPDISFTIDANK--QQRQLIAELENKNREILQEIQ 491 Query: 1066 RLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQ 1125 RL+ +HE + P P + PT L+AE +LLRQ K LE RM L++ ++ Sbjct: 492 RLRLEHE-QASQPTPEKAQQNPT---------LLAELRLLRQRKDELEQRMSALQESRRE 541 Query: 1126 LESQLHRLRQLLEQPQAEAKVN 1147 L QL L +LL++ + + V+ Sbjct: 542 LMVQLEGLMKLLKEEELKQGVS 563 >gi|42718001 dystrobrevin alpha isoform 4 [Homo sapiens] Length = 567 Score = 199 bits (506), Expect = 1e-50 Identities = 161/559 (28%), Positives = 263/559 (47%), Gaps = 72/559 (12%) Query: 637 DLNNVRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQ--PMDILQIINCL 694 DL+ +R S YRTA KLR +QK L L+ + +AL ++ L D +++ ++ L Sbjct: 26 DLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPNTELNVSRLEAVL 85 Query: 695 TTIYDRLEQEH--NNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLE 752 +TI+ +L + + ++V + + LN+LL +D G+I V + K + +LC + Sbjct: 86 STIFYQLNKRMPTTHQIHVEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIM 145 Query: 753 DKYRYLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANN 812 DK RY+F ++ S+G R L + +++P + E SFG + E S RSCF + Sbjct: 146 DKLRYIFSMISDSSGVMVYGRYDQFLREVLKLPTAVFEGPSFGYT--EQSARSCF---SQ 200 Query: 813 KPEIEAALFLDWMRLEP--QSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLK 870 + ++ FLD + +P Q +VWLP+LHR+A E H +C+ C ++GFRYR + Sbjct: 201 QKKVTLNGFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQ 260 Query: 871 HFNYDICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAK-- 928 NY +CQ CF+ G H + M EY + + AK L N A Sbjct: 261 CHNYQLCQDCFWRGHAGGSHSNQHQMKEYTS-------WKSPAKKLTNALSKSLSCASSR 313 Query: 929 ---HPRMGYLPVQTV-LEGDNMETPVTLIN------FWPVDSAP---ASSPQLSHDDTHS 975 HP P + + L PVT +N P +P SSP + + Sbjct: 314 EPLHPMFPDQPEKPLNLAHIVPPRPVTSMNDTLFSHSVPSSGSPFITRSSPPKDSEVEQN 373 Query: 976 RI-----------------EHYASRLAEMENSNGSYLN-------DSISPNESIDDEHLL 1011 ++ + A RLA+ G Y+N + + +D+EH L Sbjct: 374 KLLARAAPAFLKGKGIQYSLNVADRLADEHVLIGLYVNMLRNNPSCMLESSNRLDEEHRL 433 Query: 1012 IQHYCQSLNQDSPLSQP---RSPAQILISLESEERGELERILADLEEENRNLQAEYDRLK 1068 I Y L +S SQP RS I ++++ + + +++A+LE +NR + E RL+ Sbjct: 434 IARYAARLAAESSSSQPPQQRSAPDISFTIDANK--QQRQLIAELENKNREILQEIQRLR 491 Query: 1069 QQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEARMQILEDHNKQLES 1128 +HE + P P + PT L+AE +LLRQ K LE RM L++ ++L Sbjct: 492 LEHE-QASQPTPEKAQQNPT---------LLAELRLLRQRKDELEQRMSALQESRRELMV 541 Query: 1129 QLHRLRQLLEQPQAEAKVN 1147 QL L +LL++ + + V+ Sbjct: 542 QLEGLMKLLKEEELKQGVS 560 >gi|11276069 dystrobrevin, beta isoform 1 [Homo sapiens] Length = 627 Score = 195 bits (495), Expect = 3e-49 Identities = 158/567 (27%), Positives = 270/567 (47%), Gaps = 50/567 (8%) Query: 641 VRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDIL--QIINCLTTIY 698 +R S YRTA KLR +QK L L+ + +A + L D +I ++ +++IY Sbjct: 30 IRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETVISSIY 89 Query: 699 DRLEQE--HNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYR 756 +L + + ++V + + LN+++ YD+ G++ V S K + ++C + DK R Sbjct: 90 YQLNKRLPSTHQISVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLR 149 Query: 757 YLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEI 816 Y+F Q++ S G + L + +++P + E SFG + E SVR+CF + +I Sbjct: 150 YVFSQMSDSNGLMIFSKFDQFLKEVLKLPTAVFEGPSFGYT--EHSVRTCFP---QQRKI 204 Query: 817 EAALFLDWMRLEP--QSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNY 874 +FLD M +P Q +VWLP++HR+A E H +C+ C+ ++GFRYR + NY Sbjct: 205 MLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCRCESMMGFRYRCQQCHNY 264 Query: 875 DICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGY 934 +CQ+CF+ G H + M E+ + + + + T+ HP Sbjct: 265 QLCQNCFWRGHAGGPHSNQHQMKEHSSWKSPAKKLSHAISKSLGCVPTRE--PPHPVFPE 322 Query: 935 LPVQTV-LEGDNMETPVTLINFWPVDSAPASSP------QLSHD------DTHSRIEHYA 981 P + + L P+T +N V + P Q S D D H+ I Y Sbjct: 323 QPEKPLDLAHIVPPRPLTNMNDTMVSHMSSGVPTPTKRLQYSQDIPSHLADEHALIASYV 382 Query: 982 SRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESE 1041 +RL + + + DS S +D+EH LI Y L ++ + R P + + ++ Sbjct: 383 ARL-----QHCARVLDSPS---RLDEEHRLIARYAARLAAEAG-NVTRPPTDLSFNFDAN 433 Query: 1042 ERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAE 1101 + + +++A+LE +NR + E RL+ +HE + P P + PT L+AE Sbjct: 434 K--QQRQLIAELENKNREILQEIQRLRLEHE-QASQPTPEKAQQNPT---------LLAE 481 Query: 1102 AKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTS-LQR 1160 +LLRQ K LE RM L++ ++L QL L +LL++ + + T SP TS Sbjct: 482 LRLLRQRKDELEQRMSALQESRRELMVQLEELMKLLKEEEQKQAAQAT--GSPHTSPTHG 539 Query: 1161 SDSSQPMLLRVVGSQTSDSMGEEDLLS 1187 PM +R + ++ + +D LS Sbjct: 540 GGRPMPMPVRSTSAGSTPTHCPQDSLS 566 Score = 32.3 bits (72), Expect = 2.8 Identities = 35/159 (22%), Positives = 71/159 (44%), Gaps = 22/159 (13%) Query: 216 RVSEREAALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLL--EDSKGVKE 273 RV + + L+E HRL+ ++ L +T T + DA +++R L E +E Sbjct: 390 RVLDSPSRLDEEHRLIARYAARLAAEAGNVTRPPTDLSFNFDANKQQRQLIAELENKNRE 449 Query: 274 LMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKS 333 ++++ Q L+ E H E +Q+ + +L + RL LR++ Sbjct: 450 ILQEIQRLRLE---HEQASQPTPEKAQQ--------NPTLLAELRL---------LRQRK 489 Query: 334 LNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQA 372 + + A + + L + L+EL+ L+ ++ + + QA Sbjct: 490 DELEQRMSALQESRRELMVQLEELMKLLKEEEQKQAAQA 528 >gi|37577099 dystrobrevin, beta isoform 2 [Homo sapiens] Length = 597 Score = 195 bits (495), Expect = 3e-49 Identities = 158/567 (27%), Positives = 270/567 (47%), Gaps = 50/567 (8%) Query: 641 VRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDIL--QIINCLTTIY 698 +R S YRTA KLR +QK L L+ + +A + L D +I ++ +++IY Sbjct: 30 IRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETVISSIY 89 Query: 699 DRLEQE--HNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYR 756 +L + + ++V + + LN+++ YD+ G++ V S K + ++C + DK R Sbjct: 90 YQLNKRLPSTHQISVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLR 149 Query: 757 YLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEI 816 Y+F Q++ S G + L + +++P + E SFG + E SVR+CF + +I Sbjct: 150 YVFSQMSDSNGLMIFSKFDQFLKEVLKLPTAVFEGPSFGYT--EHSVRTCFP---QQRKI 204 Query: 817 EAALFLDWMRLEP--QSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNY 874 +FLD M +P Q +VWLP++HR+A E H +C+ C+ ++GFRYR + NY Sbjct: 205 MLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCRCESMMGFRYRCQQCHNY 264 Query: 875 DICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGY 934 +CQ+CF+ G H + M E+ + + + + T+ HP Sbjct: 265 QLCQNCFWRGHAGGPHSNQHQMKEHSSWKSPAKKLSHAISKSLGCVPTRE--PPHPVFPE 322 Query: 935 LPVQTV-LEGDNMETPVTLINFWPVDSAPASSP------QLSHD------DTHSRIEHYA 981 P + + L P+T +N V + P Q S D D H+ I Y Sbjct: 323 QPEKPLDLAHIVPPRPLTNMNDTMVSHMSSGVPTPTKRLQYSQDIPSHLADEHALIASYV 382 Query: 982 SRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESE 1041 +RL + + + DS S +D+EH LI Y L ++ + R P + + ++ Sbjct: 383 ARL-----QHCARVLDSPS---RLDEEHRLIARYAARLAAEAG-NVTRPPTDLSFNFDAN 433 Query: 1042 ERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAE 1101 + + +++A+LE +NR + E RL+ +HE + P P + PT L+AE Sbjct: 434 K--QQRQLIAELENKNREILQEIQRLRLEHE-QASQPTPEKAQQNPT---------LLAE 481 Query: 1102 AKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTS-LQR 1160 +LLRQ K LE RM L++ ++L QL L +LL++ + + T SP TS Sbjct: 482 LRLLRQRKDELEQRMSALQESRRELMVQLEELMKLLKEEEQKQAAQAT--GSPHTSPTHG 539 Query: 1161 SDSSQPMLLRVVGSQTSDSMGEEDLLS 1187 PM +R + ++ + +D LS Sbjct: 540 GGRPMPMPVRSTSAGSTPTHCPQDSLS 566 Score = 32.3 bits (72), Expect = 2.8 Identities = 35/159 (22%), Positives = 71/159 (44%), Gaps = 22/159 (13%) Query: 216 RVSEREAALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLL--EDSKGVKE 273 RV + + L+E HRL+ ++ L +T T + DA +++R L E +E Sbjct: 390 RVLDSPSRLDEEHRLIARYAARLAAEAGNVTRPPTDLSFNFDANKQQRQLIAELENKNRE 449 Query: 274 LMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKS 333 ++++ Q L+ E H E +Q+ + +L + RL LR++ Sbjct: 450 ILQEIQRLRLE---HEQASQPTPEKAQQ--------NPTLLAELRL---------LRQRK 489 Query: 334 LNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQA 372 + + A + + L + L+EL+ L+ ++ + + QA Sbjct: 490 DELEQRMSALQESRRELMVQLEELMKLLKEEEQKQAAQA 528 >gi|37577095 dystrobrevin, beta isoform 4 [Homo sapiens] Length = 609 Score = 195 bits (495), Expect = 3e-49 Identities = 158/567 (27%), Positives = 270/567 (47%), Gaps = 50/567 (8%) Query: 641 VRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDIL--QIINCLTTIY 698 +R S YRTA KLR +QK L L+ + +A + L D +I ++ +++IY Sbjct: 30 IRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETVISSIY 89 Query: 699 DRLEQE--HNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYR 756 +L + + ++V + + LN+++ YD+ G++ V S K + ++C + DK R Sbjct: 90 YQLNKRLPSTHQISVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLR 149 Query: 757 YLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEI 816 Y+F Q++ S G + L + +++P + E SFG + E SVR+CF + +I Sbjct: 150 YVFSQMSDSNGLMIFSKFDQFLKEVLKLPTAVFEGPSFGYT--EHSVRTCFP---QQRKI 204 Query: 817 EAALFLDWMRLEP--QSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNY 874 +FLD M +P Q +VWLP++HR+A E H +C+ C+ ++GFRYR + NY Sbjct: 205 MLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCRCESMMGFRYRCQQCHNY 264 Query: 875 DICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGY 934 +CQ+CF+ G H + M E+ + + + + T+ HP Sbjct: 265 QLCQNCFWRGHAGGPHSNQHQMKEHSSWKSPAKKLSHAISKSLGCVPTRE--PPHPVFPE 322 Query: 935 LPVQTV-LEGDNMETPVTLINFWPVDSAPASSP------QLSHD------DTHSRIEHYA 981 P + + L P+T +N V + P Q S D D H+ I Y Sbjct: 323 QPEKPLDLAHIVPPRPLTNMNDTMVSHMSSGVPTPTKRLQYSQDIPSHLADEHALIASYV 382 Query: 982 SRLAEMENSNGSYLNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESE 1041 +RL + + + DS S +D+EH LI Y L ++ + R P + + ++ Sbjct: 383 ARL-----QHCARVLDSPS---RLDEEHRLIARYAARLAAEAG-NVTRPPTDLSFNFDAN 433 Query: 1042 ERGELERILADLEEENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAE 1101 + + +++A+LE +NR + E RL+ +HE + P P + PT L+AE Sbjct: 434 K--QQRQLIAELENKNREILQEIQRLRLEHE-QASQPTPEKAQQNPT---------LLAE 481 Query: 1102 AKLLRQHKGRLEARMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTS-LQR 1160 +LLRQ K LE RM L++ ++L QL L +LL++ + + T SP TS Sbjct: 482 LRLLRQRKDELEQRMSALQESRRELMVQLEELMKLLKEEEQKQAAQAT--GSPHTSPTHG 539 Query: 1161 SDSSQPMLLRVVGSQTSDSMGEEDLLS 1187 PM +R + ++ + +D LS Sbjct: 540 GGRPMPMPVRSTSAGSTPTHCPQDSLS 566 Score = 32.3 bits (72), Expect = 2.8 Identities = 35/159 (22%), Positives = 71/159 (44%), Gaps = 22/159 (13%) Query: 216 RVSEREAALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLL--EDSKGVKE 273 RV + + L+E HRL+ ++ L +T T + DA +++R L E +E Sbjct: 390 RVLDSPSRLDEEHRLIARYAARLAAEAGNVTRPPTDLSFNFDANKQQRQLIAELENKNRE 449 Query: 274 LMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKKS 333 ++++ Q L+ E H E +Q+ + +L + RL LR++ Sbjct: 450 ILQEIQRLRLE---HEQASQPTPEKAQQ--------NPTLLAELRL---------LRQRK 489 Query: 334 LNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQA 372 + + A + + L + L+EL+ L+ ++ + + QA Sbjct: 490 DELEQRMSALQESRRELMVQLEELMKLLKEEEQKQAAQA 528 >gi|15147341 dystrobrevin, beta isoform 3 [Homo sapiens] Length = 567 Score = 192 bits (489), Expect = 1e-48 Identities = 152/554 (27%), Positives = 263/554 (47%), Gaps = 54/554 (9%) Query: 641 VRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDIL--QIINCLTTIY 698 +R S YRTA KLR +QK L L+ + +A + L D +I ++ +++IY Sbjct: 30 IRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETVISSIY 89 Query: 699 DRLEQE--HNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYR 756 +L + + ++V + + LN+++ YD+ G++ V S K + ++C + DK R Sbjct: 90 YQLNKRLPSTHQISVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLR 149 Query: 757 YLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEI 816 Y+F Q++ S G + L + +++P + E SFG + E SVR+CF + +I Sbjct: 150 YVFSQMSDSNGLMIFSKFDQFLKEVLKLPTAVFEGPSFGYT--EHSVRTCFP---QQRKI 204 Query: 817 EAALFLDWMRLEP--QSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNY 874 +FLD M +P Q +VWLP++HR+A E H +C+ C+ ++GFRYR + NY Sbjct: 205 MLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCRCESMMGFRYRCQQCHNY 264 Query: 875 DICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGY 934 +CQ+CF+ G H + M E+ + + + K A +G Sbjct: 265 QLCQNCFWRGHAGGPHSNQHQMKEHSSWKSPAK---------------KLSHAISKSLGC 309 Query: 935 LPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSY 994 +P + E P P+D A P+ + + + H +S + S Sbjct: 310 VPTREPPHPVFPEQPEK-----PLDLAHIVPPRPLTNMNDTMVSHMSSGVPTPTKS---- 360 Query: 995 LNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLE 1054 + DS S +D+EH LI Y L ++ + R P + + ++ + + +++A+LE Sbjct: 361 VLDSPS---RLDEEHRLIARYAARLAAEAG-NVTRPPTDLSFNFDANK--QQRQLIAELE 414 Query: 1055 EENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEA 1114 +NR + E RL+ +HE + P P + PT L+AE +LLRQ K LE Sbjct: 415 NKNREILQEIQRLRLEHE-QASQPTPEKAQQNPT---------LLAELRLLRQRKDELEQ 464 Query: 1115 RMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTS-LQRSDSSQPMLLRVVG 1173 RM L++ ++L QL L +LL++ + + T SP TS PM +R Sbjct: 465 RMSALQESRRELMVQLEELMKLLKEEEQKQAAQAT--GSPHTSPTHGGGRPMPMPVRSTS 522 Query: 1174 SQTSDSMGEEDLLS 1187 + ++ + +D LS Sbjct: 523 AGSTPTHCPQDSLS 536 Score = 32.0 bits (71), Expect = 3.7 Identities = 35/160 (21%), Positives = 71/160 (44%), Gaps = 22/160 (13%) Query: 215 KRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLL--EDSKGVK 272 K V + + L+E HRL+ ++ L +T T + DA +++R L E + Sbjct: 359 KSVLDSPSRLDEEHRLIARYAARLAAEAGNVTRPPTDLSFNFDANKQQRQLIAELENKNR 418 Query: 273 ELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKK 332 E++++ Q L+ E H E +Q+ + +L + RL LR++ Sbjct: 419 EILQEIQRLRLE---HEQASQPTPEKAQQ--------NPTLLAELRL---------LRQR 458 Query: 333 SLNIRSHLEASSDQWKRLHLSLQELLVWLQLKDDELSRQA 372 + + A + + L + L+EL+ L+ ++ + + QA Sbjct: 459 KDELEQRMSALQESRRELMVQLEELMKLLKEEEQKQAAQA 498 >gi|37577097 dystrobrevin, beta isoform 5 [Homo sapiens] Length = 560 Score = 190 bits (482), Expect = 8e-48 Identities = 152/553 (27%), Positives = 264/553 (47%), Gaps = 59/553 (10%) Query: 641 VRFSAYRTAMKLRRLQKALCLDLLSLSAACDALDQHNLKQNDQPMDIL--QIINCLTTIY 698 +R S YRTA KLR +QK L L+ + +A + L D +I ++ +++IY Sbjct: 30 IRLSTYRTACKLRFVQKRCNLHLVDIWNMIEAFRDNGLNTLDHTTEISVSRLETVISSIY 89 Query: 699 DRLEQE--HNNLVNVPLCVDMCLNWLLNVYDTGRTGRIRVLSFKTGIISLCKAHLEDKYR 756 +L + + ++V + + LN+++ YD+ G++ V S K + ++C + DK R Sbjct: 90 YQLNKRLPSTHQISVEQSISLLLNFMIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLR 149 Query: 757 YLFKQVASSTGFCDQRRLGLLLHDSIQIPRQLGEVASFGGSNIEPSVRSCFQFANNKPEI 816 Y+F Q++ S G + L + +++P + E SFG + E SVR+CF + +I Sbjct: 150 YVFSQMSDSNGLMIFSKFDQFLKEVLKLPTAVFEGPSFGYT--EHSVRTCFP---QQRKI 204 Query: 817 EAALFLDWMRLEP--QSMVWLPVLHRVAAAETAKHQAKCNICKECPIIGFRYRSLKHFNY 874 +FLD M +P Q +VWLP++HR+A E H +C+ C+ ++GFRYR + NY Sbjct: 205 MLNMFLDTMMADPPPQCLVWLPLMHRLAHVENVFHPVECSYCRCESMMGFRYRCQQCHNY 264 Query: 875 DICQSCFFSGRVAKGHKMHYPMVEYCTPTTSGEDVRDFAKVLKNKFRTKRYFAKHPRMGY 934 +CQ+CF+ G H + M E+ + + + K A +G Sbjct: 265 QLCQNCFWRGHAGGPHSNQHQMKEHSSWKSPAK---------------KLSHAISKSLGC 309 Query: 935 LPVQTVLEGDNMETPVTLINFWPVDSAPASSPQLSHDDTHSRIEHYASRLAEMENSNGSY 994 +P + E P P+D A P+ + + + H +S + S Sbjct: 310 VPTREPPHPVFPEQPEK-----PLDLAHIVPPRPLTNMNDTMVSHMSSGVPTPTKS---- 360 Query: 995 LNDSISPNESIDDEHLLIQHYCQSLNQDSPLSQPRSPAQILISLESEERGELERILADLE 1054 + DS S +D+EH LI Y L ++ + R P + + ++ + + +++A+LE Sbjct: 361 VLDSPS---RLDEEHRLIARYAARLAAEAG-NVTRPPTDLSFNFDANK--QQRQLIAELE 414 Query: 1055 EENRNLQAEYDRLKQQHEHKGLSPLPSPPEMMPTSPQSPRDAELIAEAKLLRQHKGRLEA 1114 +NR + E RL+ +HE + P P + PT L+AE +LLRQ K LE Sbjct: 415 NKNREILQEIQRLRLEHE-QASQPTPEKAQQNPT---------LLAELRLLRQRKDELEQ 464 Query: 1115 RMQILEDHNKQLESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGS 1174 RM L++ ++L QL L +LL +A+ G+ +SP+ R PM +R + Sbjct: 465 RMSALQESRRELMVQLEELMKLL-----KAQATGSPHTSPTHGGGR---PMPMPVRSTSA 516 Query: 1175 QTSDSMGEEDLLS 1187 ++ + +D LS Sbjct: 517 GSTPTHCPQDSLS 529 Score = 31.6 bits (70), Expect = 4.8 Identities = 30/129 (23%), Positives = 58/129 (44%), Gaps = 8/129 (6%) Query: 215 KRVSEREAALEETHRLLQQFPLDLEKFLAWLTEAETTANVLQDATRKERLL--EDSKGVK 272 K V + + L+E HRL+ ++ L +T T + DA +++R L E + Sbjct: 359 KSVLDSPSRLDEEHRLIARYAARLAAEAGNVTRPPTDLSFNFDANKQQRQLIAELENKNR 418 Query: 273 ELMKQWQDLQGEIEAHTDVYHNLDENSQKILRSLEGSDDAVLLQRRLDNMNFKWSELRKK 332 E++++ Q L+ E E + + + +L L LL++R D + + S L++ Sbjct: 419 EILQEIQRLRLEHEQASQPTPEKAQQNPTLLAELR------LLRQRKDELEQRMSALQES 472 Query: 333 SLNIRSHLE 341 + LE Sbjct: 473 RRELMVQLE 481 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.130 0.379 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 46,565,516 Number of Sequences: 37866 Number of extensions: 2140321 Number of successful extensions: 16004 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 141 Number of HSP's successfully gapped in prelim test: 680 Number of HSP's that attempted gapping in prelim test: 10709 Number of HSP's gapped (non-prelim): 3913 length of query: 1225 length of database: 18,247,518 effective HSP length: 114 effective length of query: 1111 effective length of database: 13,930,794 effective search space: 15477112134 effective search space used: 15477112134 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.