Search of human proteins with 5031735

Search of human proteins with 5031735

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5031735 carbohydrate (N-acetylglucosamine 6-O)
sulfotransferase 4 [Homo sapiens]
         (386 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5031735 carbohydrate (N-acetylglucosamine 6-O) sulfotransfera...   789   0.0  
gi|11055976 carbohydrate (N-acetylglucosamine 6-O) sulfotransfer...   390   e-109
gi|21362052 carbohydrate (N-acetylglucosamine 6-O) sulfotransfer...   385   e-107
gi|23238228 chondroitin 6-sulfotransferase 7 [Homo sapiens]           227   2e-59
gi|27369497 carbohydrate (N-acetylglucosamine-6-O) sulfotransfer...   224   1e-58
gi|4502841 carbohydrate (keratan sulfate Gal-6) sulfotransferase...   205   5e-53
gi|19923281 chondroitin 6-sulfotransferase 3 [Homo sapiens]           185   7e-47
gi|23943787 dermatan sulfate epimerase-like [Homo sapiens]             38   0.014
gi|55749742 HEAT repeat containing 5B [Homo sapiens]                   32   0.74 
gi|62955805 vang-like 2 [Homo sapiens]                                 31   2.2  
gi|190684671 mitogen-activated protein kinase binding protein 1 ...    30   3.7  
gi|190684677 mitogen-activated protein kinase binding protein 1 ...    30   3.7  
gi|21618347 mitogen-activated protein kinase kinase 3 isoform A ...    29   6.3  
gi|21618349 mitogen-activated protein kinase kinase 3 isoform B ...    29   6.3  
gi|117956387 hypothetical protein LOC80133 [Homo sapiens]              29   6.3  

>gi|5031735 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase
           4 [Homo sapiens]
          Length = 386

 Score =  789 bits (2038), Expect = 0.0
 Identities = 386/386 (100%), Positives = 386/386 (100%)

Query: 1   MLLPKKMKLLLFLVSQMAILALFFHMYSHNISSLSMKAQPERMHVLVLSSWRSGSSFVGQ 60
           MLLPKKMKLLLFLVSQMAILALFFHMYSHNISSLSMKAQPERMHVLVLSSWRSGSSFVGQ
Sbjct: 1   MLLPKKMKLLLFLVSQMAILALFFHMYSHNISSLSMKAQPERMHVLVLSSWRSGSSFVGQ 60

Query: 61  LFGQHPDVFYLMEPAWHVWMTFKQSTAWMLHMAVRDLIRAVFLCDMSVFDAYMEPGPRRQ 120
           LFGQHPDVFYLMEPAWHVWMTFKQSTAWMLHMAVRDLIRAVFLCDMSVFDAYMEPGPRRQ
Sbjct: 61  LFGQHPDVFYLMEPAWHVWMTFKQSTAWMLHMAVRDLIRAVFLCDMSVFDAYMEPGPRRQ 120

Query: 121 SSLFQWENSRALCSAPACDIIPQDEIIPRAHCRLLCSQQPFEVVEKACRSYSHVVLKEVR 180
           SSLFQWENSRALCSAPACDIIPQDEIIPRAHCRLLCSQQPFEVVEKACRSYSHVVLKEVR
Sbjct: 121 SSLFQWENSRALCSAPACDIIPQDEIIPRAHCRLLCSQQPFEVVEKACRSYSHVVLKEVR 180

Query: 181 FFNLQSLYPLLKDPSLNLHIVHLVRDPRAVFRSRERTKGDLMIDSRIVMGQHEQKLKKED 240
           FFNLQSLYPLLKDPSLNLHIVHLVRDPRAVFRSRERTKGDLMIDSRIVMGQHEQKLKKED
Sbjct: 181 FFNLQSLYPLLKDPSLNLHIVHLVRDPRAVFRSRERTKGDLMIDSRIVMGQHEQKLKKED 240

Query: 241 QPYYVMQVICQSQLEIYKTIQSLPKALQERYLLVRYEDLARAPVAQTSRMYEFVGLEFLP 300
           QPYYVMQVICQSQLEIYKTIQSLPKALQERYLLVRYEDLARAPVAQTSRMYEFVGLEFLP
Sbjct: 241 QPYYVMQVICQSQLEIYKTIQSLPKALQERYLLVRYEDLARAPVAQTSRMYEFVGLEFLP 300

Query: 301 HLQTWVHNITRGKGMGDHAFHTNARDALNVSQAWRWSLPYEKVSRLQKACGDAMNLLGYR 360
           HLQTWVHNITRGKGMGDHAFHTNARDALNVSQAWRWSLPYEKVSRLQKACGDAMNLLGYR
Sbjct: 301 HLQTWVHNITRGKGMGDHAFHTNARDALNVSQAWRWSLPYEKVSRLQKACGDAMNLLGYR 360

Query: 361 HVRSEQEQRNLLLDLLSTWTVPEQIH 386
           HVRSEQEQRNLLLDLLSTWTVPEQIH
Sbjct: 361 HVRSEQEQRNLLLDLLSTWTVPEQIH 386


>gi|11055976 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase
           6 [Homo sapiens]
          Length = 395

 Score =  390 bits (1003), Expect = e-109
 Identities = 202/338 (59%), Positives = 243/338 (71%), Gaps = 5/338 (1%)

Query: 42  RMHVLVLSSWRSGSSFVGQLFGQHPDVFYLMEPAWHVWMTFKQSTAWMLHMAVRDLIRAV 101
           R+HVLVLSSWRSGSSFVGQLF QHPDVFYLMEPAWHVW T  Q +A  LHMAVRDL+R+V
Sbjct: 40  RVHVLVLSSWRSGSSFVGQLFNQHPDVFYLMEPAWHVWTTLSQGSAATLHMAVRDLVRSV 99

Query: 102 FLCDMSVFDAYMEPGPRRQSSLFQWENSRALCSAPACDIIPQDEIIPRAHCRLLCSQQPF 161
           FLCDM VFDAY+ P  R  S LFQW  SRALCS PAC   P+  I   A C+ LC++Q F
Sbjct: 100 FLCDMDVFDAYL-PWRRNLSDLFQWAVSRALCSPPACSAFPRGAISSEAVCKPLCARQSF 158

Query: 162 EVVEKACRSYSHVVLKEVRFFNLQSLYPLLKDPSLNLHIVHLVRDPRAVFRSRERTKGDL 221
            +  +ACRSYSHVVLKEVRFFNLQ LYPLL DP+LNL IVHLVRDPRAV RSRE+T   L
Sbjct: 159 TLAREACRSYSHVVLKEVRFFNLQVLYPLLSDPALNLRIVHLVRDPRAVLRSREQTAKAL 218

Query: 222 MIDSRIVMGQHEQKLKKEDQPYYVMQVICQSQLEIYKTIQ-SLPKALQERYLLVRYEDLA 280
             D+ IV+G +   + + D    V++ +C+S + I +      P  L+ RY LVR+EDLA
Sbjct: 219 ARDNGIVLGTNGTWV-EADPGLRVVREVCRSHVRIAEAATLKPPPFLRGRYRLVRFEDLA 277

Query: 281 RAPVAQTSRMYEFVGLEFLPHLQTWVHNITRGKGMG--DHAFHTNARDALNVSQAWRWSL 338
           R P+A+   +Y F GL   P L+ W+HNIT G G G    AF T++R+ALNVSQAWR +L
Sbjct: 278 REPLAEIRALYAFTGLSLTPQLEAWIHNITHGSGPGARREAFKTSSRNALNVSQAWRHAL 337

Query: 339 PYEKVSRLQKACGDAMNLLGYRHVRSEQEQRNLLLDLL 376
           P+ K+ R+Q+ C  A+ LLGYR V SE EQRNL LDL+
Sbjct: 338 PFAKIRRVQELCAGALQLLGYRPVYSEDEQRNLALDLV 375


>gi|21362052 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase
           5 [Homo sapiens]
          Length = 411

 Score =  385 bits (989), Expect = e-107
 Identities = 203/379 (53%), Positives = 255/379 (67%), Gaps = 19/379 (5%)

Query: 1   MLLPKKMKLLLFLVSQMAILALFFHMYSHNISSLSMKAQPERMHVLVLSSWRSGSSFVGQ 60
           +LL +   LLLF++S+                  S     +R+HVLVLSSWRSGSSF+GQ
Sbjct: 35  LLLAQTTCLLLFIISRPG--------------PSSPAGGEDRVHVLVLSSWRSGSSFLGQ 80

Query: 61  LFGQHPDVFYLMEPAWHVWMTFKQSTAWMLHMAVRDLIRAVFLCDMSVFDAYMEPGPRRQ 120
           LF QHPDVFYLMEPAWHVW T  Q +A  LHMAVRDL+R++FLCDM VFDAYM P  R  
Sbjct: 81  LFSQHPDVFYLMEPAWHVWTTLSQGSAATLHMAVRDLMRSIFLCDMDVFDAYM-PQSRNL 139

Query: 121 SSLFQWENSRALCSAPACDIIPQDEIIPRAHCRLLCSQQPFEVVEKACRSYSHVVLKEVR 180
           S+ F W  SRALCS PAC   P+  I  +  C+ LC++QPF +  +ACRSYSHVVLKEVR
Sbjct: 140 SAFFNWATSRALCSPPACSAFPRGTISKQDVCKTLCTRQPFSLAREACRSYSHVVLKEVR 199

Query: 181 FFNLQSLYPLLKDPSLNLHIVHLVRDPRAVFRSRERTKGDLMIDSRIVMGQHEQKLKKED 240
           FFNLQ LYPLL DP+LNL IVHLVRDPRAV RSRE     L  D+ IV+G +  K  + D
Sbjct: 200 FFNLQVLYPLLSDPALNLRIVHLVRDPRAVLRSREAAGPILARDNGIVLGTN-GKWVEAD 258

Query: 241 QPYYVMQVICQSQLEIYKTIQ-SLPKALQERYLLVRYEDLARAPVAQTSRMYEFVGLEFL 299
               +++ +C+S + I +      P  L+ RY LVR+EDLAR P+A+   +Y F GL   
Sbjct: 259 PHLRLIREVCRSHVRIAEAATLKPPPFLRGRYRLVRFEDLAREPLAEIRALYAFTGLTLT 318

Query: 300 PHLQTWVHNITRGKGMGD--HAFHTNARDALNVSQAWRWSLPYEKVSRLQKACGDAMNLL 357
           P L+ W+HNIT G G+G    AFHT++R+A NVSQAWR +LP+ K+ R+Q+ C  A+ LL
Sbjct: 319 PQLEAWIHNITHGSGIGKPIEAFHTSSRNARNVSQAWRHALPFTKILRVQEVCAGALQLL 378

Query: 358 GYRHVRSEQEQRNLLLDLL 376
           GYR V S  +QR+L LDL+
Sbjct: 379 GYRPVYSADQQRDLTLDLV 397


>gi|23238228 chondroitin 6-sulfotransferase 7 [Homo sapiens]
          Length = 486

 Score =  227 bits (578), Expect = 2e-59
 Identities = 132/360 (36%), Positives = 184/360 (51%), Gaps = 41/360 (11%)

Query: 41  ERMHVLVLSSWRSGSSFVGQLFGQHPDVFYLMEPAWHVWMTFKQSTAWMLHMAVRDLIRA 100
           E+ H+ V ++WR+GSSF+G+LF QHPDVFYL EP WH+W       A  L  A+RD++R+
Sbjct: 100 EKQHIYVHATWRTGSSFLGELFNQHPDVFYLYEPMWHLWQALYPGDAESLQGALRDMLRS 159

Query: 101 VFLCDMSVFDAYMEPGPRRQ----------SSLFQWENSRALCSAPACDIIPQDE----I 146
           +F CD SV   Y  PG              ++LF+W  ++ +CS P C   P+      +
Sbjct: 160 LFRCDFSVLRLYAPPGDPAARAPDTANLTTAALFRWRTNKVICSPPLCPGAPRARAEVGL 219

Query: 147 IPRAHCRLLCSQQPFEVVEKACRSYSHVVLKEVRFFNLQSLYPLLKDPSLNLHIVHLVRD 206
           +    C   C       +E  CR Y  VV+K+VR  +L  L PLL+DP LNL +V L RD
Sbjct: 220 VEDTACERSCPPVAIRALEAECRKYPVVVIKDVRLLDLGVLVPLLRDPGLNLKVVQLFRD 279

Query: 207 PRAVFRSRERTKGDLMIDSRIVM-----------------------GQHEQKLKKEDQPY 243
           PRAV  SR +++  L+ +S  V+                       GQ           +
Sbjct: 280 PRAVHNSRLKSRQGLLRESIQVLRTRQRGDRFHRVLLAHGVGARPGGQSRALPAAPRADF 339

Query: 244 YV---MQVICQSQLEIYKTIQSLPKALQERYLLVRYEDLARAPVAQTSRMYEFVGLEFLP 300
           ++   ++VIC++ L      +  P  L+ RYL +RYEDL R P AQ  R+  F GL  L 
Sbjct: 340 FLTGALEVICEAWLRDLLFARGAPAWLRRRYLRLRYEDLVRQPRAQLRRLLRFSGLRALA 399

Query: 301 HLQTWVHNITRGKGMG-DHAFHTNARDALNVSQAWRWSLPYEKVSRLQKACGDAMNLLGY 359
            L  +  N+TRG   G D  FH +ARDA     AWR  L  E+V +++ AC  AM LL Y
Sbjct: 400 ALDAFALNMTRGAAYGADRPFHLSARDAREAVHAWRERLSREQVRQVEAACAPAMRLLAY 459


>gi|27369497 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase
           2 [Homo sapiens]
          Length = 530

 Score =  224 bits (571), Expect = 1e-58
 Identities = 132/364 (36%), Positives = 198/364 (54%), Gaps = 29/364 (7%)

Query: 41  ERMHVLVLSSWRSGSSFVGQLFGQHPDVFYLMEPAWHVWMTFKQSTAWMLHMAVRDLIRA 100
           +R  V V ++WRSGSSF G+LF Q+P+VF+L EP WHVW       A  L  A RD++ A
Sbjct: 163 KRQLVYVFTTWRSGSSFFGELFNQNPEVFFLYEPVWHVWQKLYPGDAVSLQGAARDMLSA 222

Query: 101 VFLCDMSVFDAYMEPGPRRQS----SLFQWENSRALCSAPACDIIPQDEIIPRAHCRLL- 155
           ++ CD+SVF  Y   G   ++     +F    ++ +CS+P C    + E++     R+  
Sbjct: 223 LYRCDLSVFQLYSPAGSGGRNLTTLGIFGAATNKVVCSSPLCPAY-RKEVVGLVDDRVCK 281

Query: 156 -CSQQPFEVVEKACRSYSHVVLKEVRFFNLQSLYPLLKDPSLNLHIVHLVRDPRAVFRSR 214
            C  Q     E+ CR Y  +V+K VR F++  L PLL+DP+L+L ++HLVRDPRAV  SR
Sbjct: 282 KCPPQRLARFEEECRKYRTLVIKGVRVFDVAVLAPLLRDPALDLKVIHLVRDPRAVASSR 341

Query: 215 ERTKGDLMIDSRIVMGQ---------------HEQKLKKED----QPYYV---MQVICQS 252
            R++  L+ +S  V+                 H+   KKE       Y+    M+VIC S
Sbjct: 342 IRSRHGLIRESLQVVRSRDPRAHRMPFLEAAGHKLGAKKEGVGGPADYHALGAMEVICNS 401

Query: 253 QLEIYKTIQSLPKALQERYLLVRYEDLARAPVAQTSRMYEFVGLEFLPHLQTWVHNITRG 312
             +  +T    P  LQ  YL+VRYEDL   PV    R+Y+FVGL   P ++ +  N+T G
Sbjct: 402 MAKTLQTALQPPDWLQGHYLVVRYEDLVGDPVKTLRRVYDFVGLLVSPEMEQFALNMTSG 461

Query: 313 KGMGDHAFHTNARDALNVSQAWRWSLPYEKVSRLQKACGDAMNLLGYRHVRSEQEQRNLL 372
            G     F  +AR+A   + AWR +L ++++ ++++ C   M +LGY  V S +E ++L 
Sbjct: 462 SGSSSKPFVVSARNATQAANAWRTALTFQQIKQVEEFCYQPMAVLGYERVNSPEEVKDLS 521

Query: 373 LDLL 376
             LL
Sbjct: 522 KTLL 525


>gi|4502841 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
           [Homo sapiens]
          Length = 411

 Score =  205 bits (522), Expect = 5e-53
 Identities = 126/347 (36%), Positives = 187/347 (53%), Gaps = 16/347 (4%)

Query: 42  RMHVLVLSSWRSGSSFVGQLFGQHPDVFYLMEPAWHVWMT----FKQSTA----WMLHMA 93
           + H+L+L++ RSGSSFVGQLF QH DVFYL EP +HV  T    F Q  +     ++  A
Sbjct: 60  KTHILILATTRSGSSFVGQLFNQHLDVFYLFEPLYHVQNTLIPRFTQGKSPADRRVMLGA 119

Query: 94  VRDLIRAVFLCDMSVFDAYMEPGPRRQSS--LFQWENSRALCSAPACDII-PQDEIIPRA 150
            RDL+R+++ CD+   + Y++P P   ++  +F+   SR LCS P CD   P D ++   
Sbjct: 120 SRDLLRSLYDCDLYFLENYIKPPPVNHTTDRIFRRGASRVLCSRPVCDPPGPADLVLEEG 179

Query: 151 HCRLLCSQQPFEVVEKACRSYSHVVLKEVRFFNLQSLYPLLKDPSLNLHIVHLVRDPRAV 210
            C   C      V  +ACR  SHV +K VR   +  L  L++DP LNL ++ LVRDPR +
Sbjct: 180 DCVRKCGLLNLTVAAEACRERSHVAIKTVRVPEVNDLRALVEDPRLNLKVIQLVRDPRGI 239

Query: 211 FRSRERTKGDLMIDSRIVMGQHEQKLKKEDQPYYVMQVICQSQLEIYKTIQSLPKALQER 270
             SR  T  D     R+  G      K  +     +  +C+       T    P  L+ +
Sbjct: 240 LASRSETFRDTYRLWRLWYGTGR---KPYNLDVTQLTTVCEDFSNSVSTGLMRPPWLKGK 296

Query: 271 YLLVRYEDLARAPVAQTSRMYEFVGLEFLPHLQTWVHNITRG-KGMGDHAFHTNARDALN 329
           Y+LVRYEDLAR P+ +T  +Y F+G+    H+  W+ N TRG   +G H + T  R++  
Sbjct: 297 YMLVRYEDLARNPMKKTEEIYGFLGIPLDSHVARWIQNNTRGDPTLGKHKYGT-VRNSAA 355

Query: 330 VSQAWRWSLPYEKVSRLQKACGDAMNLLGYRHVRSEQEQRNLLLDLL 376
            ++ WR+ L Y+ V+  Q AC   +  LGY+   SE+E +N  + L+
Sbjct: 356 TAEKWRFRLSYDIVAFAQNACQQVLAQLGYKIAASEEELKNPSVSLV 402


>gi|19923281 chondroitin 6-sulfotransferase 3 [Homo sapiens]
          Length = 479

 Score =  185 bits (469), Expect = 7e-47
 Identities = 111/343 (32%), Positives = 180/343 (52%), Gaps = 12/343 (3%)

Query: 42  RMHVLVLSSWRSGSSFVGQLFGQHPDVFYLMEPAWHVWMTFK----QSTAWMLHMAVRDL 97
           R HVL++++ R+GSSFVG+ F Q  ++FYL EP WH+  T       + A    +  RD+
Sbjct: 132 RRHVLLMATTRTGSSFVGEFFNQQGNIFYLFEPLWHIERTVSFEPGGANAAGSALVYRDV 191

Query: 98  IRAVFLCDMSVFDAYMEPGPRRQSSLFQWE--NSRALCSAPACDIIPQDEIIPRAHCR-L 154
           ++ +FLCD+ V + ++ P P    + F +   +SR+LC  P C    + ++  + HC+  
Sbjct: 192 LKQLFLCDLYVLEHFITPLPEDHLTQFMFRRGSSRSLCEDPVCTPFVK-KVFEKYHCKNR 250

Query: 155 LCSQQPFEVVEKACRSYSHVVLKEVRFFNLQSLYPLLKDPSLNLHIVHLVRDPRAVFRSR 214
            C      +  +ACR   H+ LK VR   L+ L PL +DP L+L ++ LVRDPRAV  SR
Sbjct: 251 RCGPLNVTLAAEACRRKEHMALKAVRIRQLEFLQPLAEDPRLDLRVIQLVRDPRAVLASR 310

Query: 215 -ERTKGDLMIDSRIVMGQHEQKLKKEDQPYYVMQVICQSQLEIYKTIQSLPKALQERYLL 273
                G      + +  + +  L++E+     ++  C+S     +     P  L+ RY+L
Sbjct: 311 MVAFAGKYKTWKKWLDDEGQDGLREEE--VQRLRGNCESIRLSAELGLRQPAWLRGRYML 368

Query: 274 VRYEDLARAPVAQTSRMYEFVGLEFLPHLQTWVHNITRGKGMGDHAFHTNARDALNVSQA 333
           VRYED+AR P+ +   MY F G+   P ++ W+   T+    G   + T  +++    + 
Sbjct: 369 VRYEDVARGPLQKAREMYRFAGIPLTPQVEDWIQKNTQAAHDGSGIYSTQ-KNSSEQFEK 427

Query: 334 WRWSLPYEKVSRLQKACGDAMNLLGYRHVRSEQEQRNLLLDLL 376
           WR+S+P++    +Q ACG AM L GY+  R      N  + LL
Sbjct: 428 WRFSMPFKLAQVVQAACGPAMRLFGYKLARDAAALTNRSVSLL 470


>gi|23943787 dermatan sulfate epimerase-like [Homo sapiens]
          Length = 1222

 Score = 38.1 bits (87), Expect = 0.014
 Identities = 39/178 (21%), Positives = 73/178 (41%), Gaps = 12/178 (6%)

Query: 187  LYPLLKDPSLNLHIVHLVRDPRAVFRSRERTKGDLMIDSRIVMGQHEQKLKKEDQPYYVM 246
            +Y +L +   +L+ +  V +  A     E  KG   ++S        + L+KE       
Sbjct: 1047 IYSMLYNSKPSLYSLKNVPEHLAKLFKIEGGKGKCNLNSGYAF--EYEPLRKELSKSKSN 1104

Query: 247  QVICQSQLEIYKTIQSL---PKALQERYLLVRYEDLARAPVAQTSRMYEFVGLEFLPHLQ 303
             V   S L +  T  +L      L   Y LV++ED+   P   T R++ F+G+   P   
Sbjct: 1105 AVSLLSHLWLANTAAALRINTDLLPTSYQLVKFEDIVHFPQKTTERIFAFLGIPLSPASL 1164

Query: 304  TWVHNITRGKGMGDHAFHTNARDALNV--SQAWRWSLPYEKVSRLQKACGDAMNLLGY 359
              +   T       + F+      ++   +  W+ +LP +++  ++  C   M+ LGY
Sbjct: 1165 NQILFAT-----STNLFYLPYEGEISPTNTNVWKQNLPRDEIKLIENICWTLMDRLGY 1217


>gi|55749742 HEAT repeat containing 5B [Homo sapiens]
          Length = 2071

 Score = 32.3 bits (72), Expect = 0.74
 Identities = 37/134 (27%), Positives = 56/134 (41%), Gaps = 15/134 (11%)

Query: 69   FYLMEPAWHVWMTFKQSTAWMLHMAVRDLIRAVFLCDMSVFDAYMEPGPRRQSSLFQWEN 128
            FY  E      + ++ S A +LH     L    F C  S   A +    +R +S+   + 
Sbjct: 1511 FYTPETIDTARLHYRNSWAPILHAVALWLNSTGFTCSESTEAAAISGLQKRSTSVNLNQA 1570

Query: 129  SRALCSAPACDIIPQD--EIIPRAHCRLLCSQQPFEVVEKACRSYSHVVLKEVRFFNLQS 186
            S A+ SA +   I +D   +I     + LCS +P E +E       HV         LQ+
Sbjct: 1571 SGAVGSAKSLPEINKDRMHLILGVSIQFLCSPRPEEPIE-------HVTA------CLQA 1617

Query: 187  LYPLLKDPSLNLHI 200
            L+ LL  P   +HI
Sbjct: 1618 LHTLLDSPYARVHI 1631


>gi|62955805 vang-like 2 [Homo sapiens]
          Length = 521

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 22/68 (32%), Positives = 31/68 (45%), Gaps = 4/68 (5%)

Query: 205 RDPRAVFRSRERTKGDLMIDSRIVMGQHEQKLKKEDQPYYVMQVICQSQLEIYKTIQSLP 264
           ++PR V   RE  +    I + +     +     + QPY+ M+ I Q  LE   T    P
Sbjct: 379 KNPREVMDPREAAQA---IFASMARAMQKYLRTTKQQPYHTMESILQ-HLEFCITHDMTP 434

Query: 265 KALQERYL 272
           KA  ERYL
Sbjct: 435 KAFLERYL 442


>gi|190684671 mitogen-activated protein kinase binding protein 1
           isoform a [Homo sapiens]
          Length = 1508

 Score = 30.0 bits (66), Expect = 3.7
 Identities = 38/153 (24%), Positives = 64/153 (41%), Gaps = 24/153 (15%)

Query: 115 PGPRRQSSLFQWENSRALCSAPACDIIPQDEIIPRAHCRLLCSQQPFEVVEKACRSYSHV 174
           P P    SL  WE SRA  S    D  P     PR   R +   QP   VE + RS    
Sbjct: 812 PSPALPRSLSHWEMSRAQESVGFLDPAPAANPGPRRRGRWV---QP--GVELSVRS---- 862

Query: 175 VLKEVRFFNLQSLYPLLKDPSLNLHIVHLVRDPRAVFRSRERTKGDLMIDSRIVMGQHEQ 234
            + ++R   L++L P L+DPS         +D  A+  S  R  G   +++ +     + 
Sbjct: 863 -MLDLR--QLETLAPSLQDPS---------QDSLAIIPSGPRKHGQEALETSLTSQNEKP 910

Query: 235 KLKKEDQPY---YVMQVICQSQLEIYKTIQSLP 264
              +  QP    ++++++ Q +    + ++  P
Sbjct: 911 PRPQASQPCSYPHIIRLLSQEEGVFAQDLEPAP 943


>gi|190684677 mitogen-activated protein kinase binding protein 1
           isoform b [Homo sapiens]
          Length = 1514

 Score = 30.0 bits (66), Expect = 3.7
 Identities = 38/153 (24%), Positives = 64/153 (41%), Gaps = 24/153 (15%)

Query: 115 PGPRRQSSLFQWENSRALCSAPACDIIPQDEIIPRAHCRLLCSQQPFEVVEKACRSYSHV 174
           P P    SL  WE SRA  S    D  P     PR   R +   QP   VE + RS    
Sbjct: 818 PSPALPRSLSHWEMSRAQESVGFLDPAPAANPGPRRRGRWV---QP--GVELSVRS---- 868

Query: 175 VLKEVRFFNLQSLYPLLKDPSLNLHIVHLVRDPRAVFRSRERTKGDLMIDSRIVMGQHEQ 234
            + ++R   L++L P L+DPS         +D  A+  S  R  G   +++ +     + 
Sbjct: 869 -MLDLR--QLETLAPSLQDPS---------QDSLAIIPSGPRKHGQEALETSLTSQNEKP 916

Query: 235 KLKKEDQPY---YVMQVICQSQLEIYKTIQSLP 264
              +  QP    ++++++ Q +    + ++  P
Sbjct: 917 PRPQASQPCSYPHIIRLLSQEEGVFAQDLEPAP 949


>gi|21618347 mitogen-activated protein kinase kinase 3 isoform A
           [Homo sapiens]
          Length = 318

 Score = 29.3 bits (64), Expect = 6.3
 Identities = 21/62 (33%), Positives = 30/62 (48%), Gaps = 3/62 (4%)

Query: 315 MGDHAFHTNARDALNVSQAWRWSLPY-EKVSRLQKACGDAMNLLGYRHVRSEQEQRNLLL 373
           +GD  F   A D + +S+  R +    EKV   Q   G  M +   R   + QEQ+ LL+
Sbjct: 23  IGDRNFEVEADDLVTISELGRGAYGVVEKVRHAQS--GTIMAVKRIRATVNSQEQKRLLM 80

Query: 374 DL 375
           DL
Sbjct: 81  DL 82


>gi|21618349 mitogen-activated protein kinase kinase 3 isoform B
           [Homo sapiens]
          Length = 347

 Score = 29.3 bits (64), Expect = 6.3
 Identities = 21/62 (33%), Positives = 30/62 (48%), Gaps = 3/62 (4%)

Query: 315 MGDHAFHTNARDALNVSQAWRWSLPY-EKVSRLQKACGDAMNLLGYRHVRSEQEQRNLLL 373
           +GD  F   A D + +S+  R +    EKV   Q   G  M +   R   + QEQ+ LL+
Sbjct: 52  IGDRNFEVEADDLVTISELGRGAYGVVEKVRHAQS--GTIMAVKRIRATVNSQEQKRLLM 109

Query: 374 DL 375
           DL
Sbjct: 110 DL 111


>gi|117956387 hypothetical protein LOC80133 [Homo sapiens]
          Length = 573

 Score = 29.3 bits (64), Expect = 6.3
 Identities = 18/53 (33%), Positives = 26/53 (49%), Gaps = 2/53 (3%)

Query: 146 IIPRAHCRLLCSQQPFEVVEKACRSYSHVVLKEVRF--FNLQSLYPLLKDPSL 196
           ++P A C+ LC+  P     KA   Y   +L  + F  F    L P+LKD +L
Sbjct: 394 LMPLAACQALCTFLPLGSYRKAVAQYFPQLLTTLMFQVFYNSELKPILKDRAL 446


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.136    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,729,424
Number of Sequences: 37866
Number of extensions: 623240
Number of successful extensions: 1588
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1556
Number of HSP's gapped (non-prelim): 17
length of query: 386
length of database: 18,247,518
effective HSP length: 104
effective length of query: 282
effective length of database: 14,309,454
effective search space: 4035266028
effective search space used: 4035266028
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.