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Search of human proteins with 4885329
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4885329 free fatty acid receptor 3 [Homo sapiens]
(346 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4885329 free fatty acid receptor 3 [Homo sapiens] 706 0.0
gi|4885333 free fatty acid receptor 2 [Homo sapiens] 248 7e-66
gi|4885327 free fatty acid receptor 1 [Homo sapiens] 133 3e-31
gi|30023826 G-protein coupled purinergic receptor P2Y8 [Homo sap... 129 5e-30
gi|166362740 coagulation factor II receptor precursor [Homo sapi... 126 2e-29
gi|219281887 lysophosphatidic acid receptor 5 [Homo sapiens] 126 2e-29
gi|9966879 lysophosphatidic acid receptor 5 [Homo sapiens] 126 2e-29
gi|34577052 coagulation factor II (thrombin) receptor-like 1 pre... 125 6e-29
gi|4885311 lysophosphatidic acid receptor 4 [Homo sapiens] 121 8e-28
gi|4826706 EBV-induced G protein-coupled receptor 2 [Homo sapiens] 117 1e-26
gi|238814307 G protein-coupled receptor 17 isoform b [Homo sapiens] 116 3e-26
gi|238814305 G protein-coupled receptor 17 isoform b [Homo sapiens] 116 3e-26
gi|4885301 G protein-coupled receptor 17 isoform a [Homo sapiens] 116 3e-26
gi|238814302 G protein-coupled receptor 17 isoform a [Homo sapiens] 116 3e-26
gi|4758326 coagulation factor II (thrombin) receptor-like 2 prec... 111 8e-25
gi|89353783 coagulation factor II (thrombin) receptor-like 3 pre... 111 1e-24
gi|241982708 G-protein coupled purinergic receptor P2Y5 [Homo sa... 110 2e-24
gi|241982706 G-protein coupled purinergic receptor P2Y5 [Homo sa... 110 2e-24
gi|33695113 G-protein coupled purinergic receptor P2Y5 [Homo sap... 110 2e-24
gi|4505561 pyrimidinergic receptor P2Y4 [Homo sapiens] 108 7e-24
gi|29029612 pyrimidinergic receptor P2Y6 [Homo sapiens] 107 1e-23
gi|29029610 pyrimidinergic receptor P2Y6 [Homo sapiens] 107 1e-23
gi|29029608 pyrimidinergic receptor P2Y6 [Homo sapiens] 107 1e-23
gi|4758864 pyrimidinergic receptor P2Y6 [Homo sapiens] 107 1e-23
gi|4885057 apelin receptor [Homo sapiens] 106 3e-23
gi|148225857 G protein-coupled receptor 34 [Homo sapiens] 104 1e-22
gi|4885319 G protein-coupled receptor 34 [Homo sapiens] 104 1e-22
gi|4557861 somatostatin receptor 3 [Homo sapiens] 103 3e-22
gi|148228829 G protein-coupled receptor 1 [Homo sapiens] 103 3e-22
gi|36951012 G protein-coupled receptor 1 [Homo sapiens] 103 3e-22
>gi|4885329 free fatty acid receptor 3 [Homo sapiens]
Length = 346
Score = 706 bits (1822), Expect = 0.0
Identities = 346/346 (100%), Positives = 346/346 (100%)
Query: 1 MDTGPDQSYFSGNHWFVFSVYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTAS 60
MDTGPDQSYFSGNHWFVFSVYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTAS
Sbjct: 1 MDTGPDQSYFSGNHWFVFSVYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTAS 60
Query: 61 DLLLLLFLPFRMVEAANGMHWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHP 120
DLLLLLFLPFRMVEAANGMHWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHP
Sbjct: 61 DLLLLLFLPFRMVEAANGMHWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHP 120
Query: 121 LWYKTRPRLGQAGLVSVACWLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQLAI 180
LWYKTRPRLGQAGLVSVACWLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQLAI
Sbjct: 121 LWYKTRPRLGQAGLVSVACWLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQLAI 180
Query: 181 LLPVRLEMAVVLFVVPLIITSYCYSRLVWILGRGGSHRRQRRVAGLLAATLLNFLVCFGP 240
LLPVRLEMAVVLFVVPLIITSYCYSRLVWILGRGGSHRRQRRVAGLLAATLLNFLVCFGP
Sbjct: 181 LLPVRLEMAVVLFVVPLIITSYCYSRLVWILGRGGSHRRQRRVAGLLAATLLNFLVCFGP 240
Query: 241 YNVSHVVGYICGESPAWRIYVTLLSTLNSCVDPFVYYFSSSGFQADFHELLRRLCGLWGQ 300
YNVSHVVGYICGESPAWRIYVTLLSTLNSCVDPFVYYFSSSGFQADFHELLRRLCGLWGQ
Sbjct: 241 YNVSHVVGYICGESPAWRIYVTLLSTLNSCVDPFVYYFSSSGFQADFHELLRRLCGLWGQ 300
Query: 301 WQQESSMELKEQKGGEEQRADRPAERKTSEHSQGCGTGGQVACAES 346
WQQESSMELKEQKGGEEQRADRPAERKTSEHSQGCGTGGQVACAES
Sbjct: 301 WQQESSMELKEQKGGEEQRADRPAERKTSEHSQGCGTGGQVACAES 346
>gi|4885333 free fatty acid receptor 2 [Homo sapiens]
Length = 330
Score = 248 bits (632), Expect = 7e-66
Identities = 131/307 (42%), Positives = 193/307 (62%), Gaps = 10/307 (3%)
Query: 17 VFSVYLLTFLVGLPLNLLALVVFVGKL-QRRPVAVDVLLLNLTASDLLLLLFLPFRMVEA 75
+ Y++ FL GLP NLLAL FVG++ Q +P V +LLL+LT +DLLLLL LPF+++EA
Sbjct: 10 ILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPVHILLLSLTLADLLLLLLLPFKIIEA 69
Query: 76 ANGMHWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLWYKTRPRLGQAGLV 135
A+ W LP ++C L+ F F+++IY + LA +SIER+L VA P+ YK R +
Sbjct: 70 ASNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGISIERYLGVAFPVQYKLSRRPLYGVIA 129
Query: 136 SVACWLLASAHCSVVYVIEFSGDISH-SQGTNGTCYLEFRKDQLAILLPVRLEMAVVLFV 194
++ W+++ HC++V ++++ G TCY F +QL ++LPVRLE+ +VLF
Sbjct: 130 ALVAWVMSFGHCTIVIIVQYLNTTEQVRSGNEITCYENFTDNQLDVVLPVRLELCLVLFF 189
Query: 195 VPLIITSYCYSRLVWIL---GRGGSHRRQRRVAGLLAATLLNFLVCFGPYNVSHVVGYIC 251
+P+ +T +CY R VWI+ G+ RR RR GL TLLNFLVCFGPYNVSH+VGY
Sbjct: 190 IPMAVTIFCYWRFVWIMLSQPLVGAQRR-RRAVGLAVVTLLNFLVCFGPYNVSHLVGYHQ 248
Query: 252 GESPAWRIYVTLLSTLNSCVDPFVYYFSSSGFQADFHELLRRL----CGLWGQWQQESSM 307
+SP WR + S+LN+ +DP ++YFSSS + F L+ L L G+ ++++
Sbjct: 249 RKSPWWRSIAVVFSSLNASLDPLLFYFSSSVVRRAFGRGLQVLRNQGSSLLGRRGKDTAE 308
Query: 308 ELKEQKG 314
E +G
Sbjct: 309 GTNEDRG 315
>gi|4885327 free fatty acid receptor 1 [Homo sapiens]
Length = 300
Score = 133 bits (334), Expect = 3e-31
Identities = 92/275 (33%), Positives = 133/275 (48%), Gaps = 11/275 (4%)
Query: 18 FSVYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMVEAAN 77
F +Y+ F +G PLN+LA+ + R V LNL SDLLL + LP + VEA
Sbjct: 9 FGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALA 68
Query: 78 GMHWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLWYKTRPRLGQAGLVSV 137
WPLP LCP+ F +Y FLAA+S R+L A PL Y+ R + V
Sbjct: 69 SGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCA 128
Query: 138 ACWLLASAHCSVVYVIEFSGD-ISHSQGT-------NGTCYLEFRKDQLAILLPVRLEMA 189
A W L H +V+ +E G + HS + NG+ D A P R ++
Sbjct: 129 AIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDP-ASAGPARFSLS 187
Query: 190 VVLFVVPLIITSYCYSRLVWILGRGG-SHRRQRRVAGLLAATLLNFLVCFGPYNVSHVVG 248
++LF +PL IT++CY + L R G +HRR+ R A + LL L+C GPYN S+V
Sbjct: 188 LLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVAS 247
Query: 249 YICGE-SPAWRIYVTLLSTLNSCVDPFVYYFSSSG 282
++ +WR + + ++P V + G
Sbjct: 248 FLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRG 282
>gi|30023826 G-protein coupled purinergic receptor P2Y8 [Homo
sapiens]
Length = 359
Score = 129 bits (323), Expect = 5e-30
Identities = 91/283 (32%), Positives = 142/283 (50%), Gaps = 14/283 (4%)
Query: 20 VYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMVEAANGM 79
VY L V +P NL +L V ++ R +V + ++NL+ +DL+L LPF++ N
Sbjct: 29 VYSLVAAVSIPGNLFSLWVLCRRMGPRSPSV-IFMINLSVTDLMLASVLPFQIYYHCNRH 87
Query: 80 HWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLWYKTRPRLGQAGLVSVAC 139
HW +LC + F+ +Y + L + +S+ERFL V +PL K R A
Sbjct: 88 HWVFGVLLCNVVTVAFYANMYSSILTMTCISVERFLGVLYPLSSKRWRRRRYAVAACAGT 147
Query: 140 WLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQL---AILLPVRLEMAVVLFVVP 196
WLL S + + + + H+ G TC+ + L A+ + ++LF++P
Sbjct: 148 WLLLLTALSPLARTDLTYPV-HALGII-TCFDVLKWTMLPSVAMWAVFLFTIFILLFLIP 205
Query: 197 LIITSYCYSRLVWILGR---GGSHRRQRRVAGLLAATLLNFLVCFGPYN---VSHVVGYI 250
+IT CY+ + L R ++RR GL A LL F+ CF P N ++H+V +
Sbjct: 206 FVITVACYTATILKLLRTEEAHGREQRRRAVGLAAVVLLAFVTCFAPNNFVLLAHIVSRL 265
Query: 251 CGESPAWRIY-VTL-LSTLNSCVDPFVYYFSSSGFQADFHELL 291
+ +Y +TL LS LN+C+DPFVYYF+S FQ E L
Sbjct: 266 FYGKSYYHVYKLTLCLSCLNNCLDPFVYYFASREFQLRLREYL 308
>gi|166362740 coagulation factor II receptor precursor [Homo
sapiens]
Length = 425
Score = 126 bits (317), Expect = 2e-29
Identities = 92/299 (30%), Positives = 147/299 (49%), Gaps = 16/299 (5%)
Query: 6 DQSYFSGNHW---FVFSVYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDL 62
D S + + W FV SVY F+V LPLN++A+VVF+ K++ + AV V +L+L +D+
Sbjct: 91 DASGYLTSSWLTLFVPSVYTGVFVVSLPLNIMAIVVFILKMKVKKPAV-VYMLHLATADV 149
Query: 63 LLLLFLPFRMVEAANGMHWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLW 122
L + LPF++ +G W LC F+ +Y + L + +SI+RFL+V +P+
Sbjct: 150 LFVSVLPFKISYYFSGSDWQFGSELCRFVTAAFYCNMYASILLMTVISIDRFLAVVYPMQ 209
Query: 123 YKTRPRLGQAGLVSVACWLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQLAILL 182
+ LG+A +A W LA A + + E + + T TC+ + L
Sbjct: 210 SLSWRTLGRASFTCLAIWALAIAGVVPLLLKEQTIQVPGLNIT--TCHDVLNETLLEGYY 267
Query: 183 PVRLE-MAVVLFVVPLIITSYCYSRLVWILGRGGSHRRQR--RVAGLLAATLLNFLVCFG 239
+ V F VPLII++ CY ++ L R + R L AA F++CFG
Sbjct: 268 AYYFSAFSAVFFFVPLIISTVCYVSIIRCLSSSAVANRSKKSRALFLSAAVFCIFIICFG 327
Query: 240 PYNVSHVVGY--ICGESPAWRIYVTLL-----STLNSCVDPFVYYFSSSGFQADFHELL 291
P NV + Y + S Y L S+++ C+DP +YY++SS Q + +L
Sbjct: 328 PTNVLLIAHYSFLSHTSTTEAAYFAYLLCVCVSSISCCIDPLIYYYASSECQRYVYSIL 386
>gi|219281887 lysophosphatidic acid receptor 5 [Homo sapiens]
Length = 372
Score = 126 bits (317), Expect = 2e-29
Identities = 94/281 (33%), Positives = 135/281 (48%), Gaps = 19/281 (6%)
Query: 20 VYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMVEAANGM 79
VY L GLPLN LAL VF+ L+ V V V + NL ASDLL L LP R+ A
Sbjct: 28 VYSLVLAAGLPLNALALWVFLRALRVHSV-VSVYMCNLAASDLLFTLSLPVRLSYYALH- 85
Query: 80 HWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLWYKTRPRLGQAGLVSVAC 139
HWP P +LC +G IF +Y + +FL ++++R+ ++ HPL + R A L+ +
Sbjct: 86 HWPFPDLLCQTTGAIFQMNMYGSCIFLMLINVDRYAAIVHPLRLRHLRRPRVARLLCLGV 145
Query: 140 WLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQL--AILLPVRLEMAVVLFVVPL 197
W L + + C+ F D+L LLP+ L + F++PL
Sbjct: 146 WALILVFAVPAARVHRPSRCRYRDLEVRLCFESF-SDELWKGRLLPLVLLAEALGFLLPL 204
Query: 198 IITSYCYSRLVWILGR--GGSHRRQRRVAGLLAATLLNFLVCFGPYNVSHVV------GY 249
Y R+ W L R +R+R+ LL A L+ FL+CF PYN + V
Sbjct: 205 AAVVYSSGRVFWTLARPDATQSQRRRKTVRLLLANLVIFLLCFVPYNSTLAVYGLLRSKL 264
Query: 250 ICGESPA------WRIYVTLLSTLNSCVDPFVYYFSSSGFQ 284
+ PA + + LL+ N +DP VYYFS+ GF+
Sbjct: 265 VAASVPARDRVRGVLMVMVLLAGANCVLDPLVYYFSAEGFR 305
>gi|9966879 lysophosphatidic acid receptor 5 [Homo sapiens]
Length = 372
Score = 126 bits (317), Expect = 2e-29
Identities = 94/281 (33%), Positives = 135/281 (48%), Gaps = 19/281 (6%)
Query: 20 VYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMVEAANGM 79
VY L GLPLN LAL VF+ L+ V V V + NL ASDLL L LP R+ A
Sbjct: 28 VYSLVLAAGLPLNALALWVFLRALRVHSV-VSVYMCNLAASDLLFTLSLPVRLSYYALH- 85
Query: 80 HWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLWYKTRPRLGQAGLVSVAC 139
HWP P +LC +G IF +Y + +FL ++++R+ ++ HPL + R A L+ +
Sbjct: 86 HWPFPDLLCQTTGAIFQMNMYGSCIFLMLINVDRYAAIVHPLRLRHLRRPRVARLLCLGV 145
Query: 140 WLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQL--AILLPVRLEMAVVLFVVPL 197
W L + + C+ F D+L LLP+ L + F++PL
Sbjct: 146 WALILVFAVPAARVHRPSRCRYRDLEVRLCFESF-SDELWKGRLLPLVLLAEALGFLLPL 204
Query: 198 IITSYCYSRLVWILGR--GGSHRRQRRVAGLLAATLLNFLVCFGPYNVSHVV------GY 249
Y R+ W L R +R+R+ LL A L+ FL+CF PYN + V
Sbjct: 205 AAVVYSSGRVFWTLARPDATQSQRRRKTVRLLLANLVIFLLCFVPYNSTLAVYGLLRSKL 264
Query: 250 ICGESPA------WRIYVTLLSTLNSCVDPFVYYFSSSGFQ 284
+ PA + + LL+ N +DP VYYFS+ GF+
Sbjct: 265 VAASVPARDRVRGVLMVMVLLAGANCVLDPLVYYFSAEGFR 305
>gi|34577052 coagulation factor II (thrombin) receptor-like 1
precursor [Homo sapiens]
Length = 397
Score = 125 bits (314), Expect = 6e-29
Identities = 85/281 (30%), Positives = 153/281 (54%), Gaps = 17/281 (6%)
Query: 16 FVFSVYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMVEA 75
F+ VY + F+VGLP N +AL VF+ + +++ AV + + NL +DLL +++ P ++
Sbjct: 77 FLPIVYTIVFVVGLPSNGMALWVFLFRTKKKHPAV-IYMANLALADLLSVIWFPLKIAYH 135
Query: 76 ANGMHWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLWYKTRPRLGQAGLV 135
+G +W LC + F+ +Y + LF+ +S++R+ + +P+ + +R + A +
Sbjct: 136 IHGNNWIYGEALCNVLIGFFYGNMYCSILFMTCLSVQRYWVIVNPMGH-SRKKANIAIGI 194
Query: 136 SVACWLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQLAI--LLPVRLEMAVVLF 193
S+A WLL +YV++ + I T TC+ + +QL + + L +A+ +F
Sbjct: 195 SLAIWLLILLVTIPLYVVKQTIFIPALNIT--TCH-DVLPEQLLVGDMFNYFLSLAIGVF 251
Query: 194 VVPLIITSYCYSRLVWILGRG----GSHRRQRRVAGLLAATLLNFLVCFGPYNVSHVVGY 249
+ P +T+ Y ++ +L S ++++R L+ L +L+CF P N+ VV Y
Sbjct: 252 LFPAFLTASAYVLMIRMLRSSAMDENSEKKRKRAIKLIVTVLAMYLICFTPSNLLLVVHY 311
Query: 250 IC----GESPAWRIYVT--LLSTLNSCVDPFVYYFSSSGFQ 284
G+S + +Y+ LSTLNSC+DPFVYYF S F+
Sbjct: 312 FLIKSQGQSHVYALYIVALCLSTLNSCIDPFVYYFVSHDFR 352
>gi|4885311 lysophosphatidic acid receptor 4 [Homo sapiens]
Length = 370
Score = 121 bits (304), Expect = 8e-28
Identities = 90/293 (30%), Positives = 144/293 (49%), Gaps = 36/293 (12%)
Query: 19 SVYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMVEAANG 78
+VY + F++GL N ++L VF +++ R + + NL SDLL + LPF++ N
Sbjct: 44 AVYSVVFILGLITNSVSLFVFCFRMKMRSETA-IFITNLAVSDLLFVCTLPFKIFYNFN- 101
Query: 79 MHWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLWYKTRPRLGQAGLVSVA 138
HWP LC +SG F T IY + LFL +S++RFL++ +P +T + +V
Sbjct: 102 RHWPFGDTLCKISGTAFLTNIYGSMLFLTCISVDRFLAIVYPFRSRTIRTRRNSAIV--- 158
Query: 139 CWLLASAHCSVVYVIEFSGDISHS-------QGTNGTCYLEFRKD-QLAILLPVRLEMAV 190
C+ V+++ SG IS S TC+ F K L + + + V
Sbjct: 159 --------CAGVWILVLSGGISASLFSTTNVNNATTTCFEGFSKRVWKTYLSKITIFIEV 210
Query: 191 VLFVVPLIITSYCYSRLVWILGRGGS----HRRQRRVAGLLAATLLNFLVCFGPYNV--- 243
V F++PLI+ C S ++ L + + +++V ++ + F+VCF PYN
Sbjct: 211 VGFIIPLILNVSCSSVVLRTLRKPATLSQIGTNKKKVLKMITVHMAVFVVCFVPYNSVLF 270
Query: 244 ------SHVVGYICGESPAWRIY-VTL-LSTLNSCVDPFVYYFSSSGFQADFH 288
S + E A +Y +TL L+TLN C DPF+YYF+ FQ F+
Sbjct: 271 LYALVRSQAITNCFLERFAKIMYPITLCLATLNCCFDPFIYYFTLESFQKSFY 323
>gi|4826706 EBV-induced G protein-coupled receptor 2 [Homo sapiens]
Length = 361
Score = 117 bits (294), Expect = 1e-26
Identities = 82/294 (27%), Positives = 140/294 (47%), Gaps = 27/294 (9%)
Query: 21 YLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMVEAANGMH 80
Y L F++GL NLLALVV V +++ + + NL SD+L LP R+ A G
Sbjct: 38 YSLVFIIGLVGNLLALVVIVQN-RKKINSTTLYSTNLVISDILFTTALPTRIAYYAMGFD 96
Query: 81 WPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLWYKTRPRLGQAGLVSVACW 140
W + LC ++ +F+ Y F+ +SI+RF++V HPL Y R+ A V + W
Sbjct: 97 WRIGDALCRITALVFYINTYAGVNFMTCLSIDRFIAVVHPLRYNKIKRIEHAKGVCIFVW 156
Query: 141 LLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQLAILLP-VRLEMAVVLFVVPLII 199
+L A + + +S + TC +E+ + LP + L + +V+PLII
Sbjct: 157 ILVFAQTLPLLI----NPMSKQEAERITC-MEYPNFEETKSLPWILLGACFIGYVLPLII 211
Query: 200 TSYCYSRLVWILGRGGSHRRQRRVAGL-------LAATLLNFLVCFGPYNVSHVVGYI-- 250
CYS++ L R +G+ + ++ F++CF PY+V+ + I
Sbjct: 212 ILICYSQICCKLFRTAKQNPLTEKSGVNKKALNTIILIIVVFVLCFTPYHVAIIQHMIKK 271
Query: 251 --------CGESPAWRI---YVTLLSTLNSCVDPFVYYFSSSGFQADFHELLRR 293
C + +++I + L N C+DPF+Y+F+ G++ +L+R
Sbjct: 272 LRFSNFLECSQRHSFQISLHFTVCLMNFNCCMDPFIYFFACKGYKRKVMRMLKR 325
>gi|238814307 G protein-coupled receptor 17 isoform b [Homo sapiens]
Length = 339
Score = 116 bits (290), Expect = 3e-26
Identities = 88/292 (30%), Positives = 144/292 (49%), Gaps = 27/292 (9%)
Query: 19 SVYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMVEAANG 78
S YLL F++ L N LAL +F+ + + +V L++L +DL +L LP R+V +G
Sbjct: 36 SFYLLDFILALVGNTLALWLFI-RDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSG 94
Query: 79 MHWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLWYKTRPRLGQAGLVSVA 138
HWP I C L+GF+F+ +Y + FL +S +RFL++ HP+ R A L
Sbjct: 95 NHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAF 154
Query: 139 CWLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQLAILLPVRLEMAVVLFVVPLI 198
W++ + + + V + +H+ L+ +++ + V L +A F P I
Sbjct: 155 LWVVVAVAMAPLLVSPQTVQTNHT-----VVCLQLYREKASHHALVSLAVA---FTFPFI 206
Query: 199 ITSYCYSRLVWILGRG--GSHRRQRRVAGLLAATLLNFLVCFGPYNVSHVVGYIC----- 251
T CY ++ L +G R + + ++A L FLVCF PY+V+ V Y+
Sbjct: 207 TTVTCYLLIIRSLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSV-YVLHYRSH 265
Query: 252 GESPAWRIYVTL-------LSTLNSCVDPFVYYFSSSGFQADFHELLRRLCG 296
G S A + + L L++LN +DP +Y+F + F+ H L LCG
Sbjct: 266 GASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFR---HALCNLLCG 314
>gi|238814305 G protein-coupled receptor 17 isoform b [Homo sapiens]
Length = 339
Score = 116 bits (290), Expect = 3e-26
Identities = 88/292 (30%), Positives = 144/292 (49%), Gaps = 27/292 (9%)
Query: 19 SVYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMVEAANG 78
S YLL F++ L N LAL +F+ + + +V L++L +DL +L LP R+V +G
Sbjct: 36 SFYLLDFILALVGNTLALWLFI-RDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSG 94
Query: 79 MHWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLWYKTRPRLGQAGLVSVA 138
HWP I C L+GF+F+ +Y + FL +S +RFL++ HP+ R A L
Sbjct: 95 NHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAF 154
Query: 139 CWLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQLAILLPVRLEMAVVLFVVPLI 198
W++ + + + V + +H+ L+ +++ + V L +A F P I
Sbjct: 155 LWVVVAVAMAPLLVSPQTVQTNHT-----VVCLQLYREKASHHALVSLAVA---FTFPFI 206
Query: 199 ITSYCYSRLVWILGRG--GSHRRQRRVAGLLAATLLNFLVCFGPYNVSHVVGYIC----- 251
T CY ++ L +G R + + ++A L FLVCF PY+V+ V Y+
Sbjct: 207 TTVTCYLLIIRSLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSV-YVLHYRSH 265
Query: 252 GESPAWRIYVTL-------LSTLNSCVDPFVYYFSSSGFQADFHELLRRLCG 296
G S A + + L L++LN +DP +Y+F + F+ H L LCG
Sbjct: 266 GASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFR---HALCNLLCG 314
>gi|4885301 G protein-coupled receptor 17 isoform a [Homo sapiens]
Length = 367
Score = 116 bits (290), Expect = 3e-26
Identities = 88/292 (30%), Positives = 144/292 (49%), Gaps = 27/292 (9%)
Query: 19 SVYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMVEAANG 78
S YLL F++ L N LAL +F+ + + +V L++L +DL +L LP R+V +G
Sbjct: 64 SFYLLDFILALVGNTLALWLFI-RDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSG 122
Query: 79 MHWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLWYKTRPRLGQAGLVSVA 138
HWP I C L+GF+F+ +Y + FL +S +RFL++ HP+ R A L
Sbjct: 123 NHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAF 182
Query: 139 CWLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQLAILLPVRLEMAVVLFVVPLI 198
W++ + + + V + +H+ L+ +++ + V L +A F P I
Sbjct: 183 LWVVVAVAMAPLLVSPQTVQTNHT-----VVCLQLYREKASHHALVSLAVA---FTFPFI 234
Query: 199 ITSYCYSRLVWILGRG--GSHRRQRRVAGLLAATLLNFLVCFGPYNVSHVVGYIC----- 251
T CY ++ L +G R + + ++A L FLVCF PY+V+ V Y+
Sbjct: 235 TTVTCYLLIIRSLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSV-YVLHYRSH 293
Query: 252 GESPAWRIYVTL-------LSTLNSCVDPFVYYFSSSGFQADFHELLRRLCG 296
G S A + + L L++LN +DP +Y+F + F+ H L LCG
Sbjct: 294 GASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFR---HALCNLLCG 342
>gi|238814302 G protein-coupled receptor 17 isoform a [Homo sapiens]
Length = 367
Score = 116 bits (290), Expect = 3e-26
Identities = 88/292 (30%), Positives = 144/292 (49%), Gaps = 27/292 (9%)
Query: 19 SVYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMVEAANG 78
S YLL F++ L N LAL +F+ + + +V L++L +DL +L LP R+V +G
Sbjct: 64 SFYLLDFILALVGNTLALWLFI-RDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSG 122
Query: 79 MHWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLWYKTRPRLGQAGLVSVA 138
HWP I C L+GF+F+ +Y + FL +S +RFL++ HP+ R A L
Sbjct: 123 NHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAF 182
Query: 139 CWLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQLAILLPVRLEMAVVLFVVPLI 198
W++ + + + V + +H+ L+ +++ + V L +A F P I
Sbjct: 183 LWVVVAVAMAPLLVSPQTVQTNHT-----VVCLQLYREKASHHALVSLAVA---FTFPFI 234
Query: 199 ITSYCYSRLVWILGRG--GSHRRQRRVAGLLAATLLNFLVCFGPYNVSHVVGYIC----- 251
T CY ++ L +G R + + ++A L FLVCF PY+V+ V Y+
Sbjct: 235 TTVTCYLLIIRSLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSV-YVLHYRSH 293
Query: 252 GESPAWRIYVTL-------LSTLNSCVDPFVYYFSSSGFQADFHELLRRLCG 296
G S A + + L L++LN +DP +Y+F + F+ H L LCG
Sbjct: 294 GASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFR---HALCNLLCG 342
>gi|4758326 coagulation factor II (thrombin) receptor-like 2
precursor [Homo sapiens]
Length = 374
Score = 111 bits (278), Expect = 8e-25
Identities = 75/273 (27%), Positives = 126/273 (46%), Gaps = 20/273 (7%)
Query: 19 SVYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMVEAANG 78
++YLL F+VG+P N + L + + R + V NL +D L + LPF++ NG
Sbjct: 99 AIYLLVFVVGVPANAVTLWMLF--FRTRSICTTVFYTNLAIADFLFCVTLPFKIAYHLNG 156
Query: 79 MHWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLWYKTRPRLGQAGLVSVA 138
+W +LC + IF+ +Y + L LA +SI R+L++ HP Y+ P+ A +
Sbjct: 157 NNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGL 216
Query: 139 CWLLASAHCSVVYVIE-----FSGDISHSQGTNGTCYLEFRKDQLAILLPVRLEMAVVLF 193
W + ++++ DI+ + TC + L + +A F
Sbjct: 217 VWATVFLYMLPFFILKQEYYLVQPDITTCHDVHNTC-----ESSSPFQLYYFISLAFFGF 271
Query: 194 VVPLIITSYCYSRLVWILGRGGSHRRQRRVAGLLAATLLNFLVCFGPYN----VSHVVGY 249
++P ++ YCY+ ++ L HR V L L+ F +CF P N + H Y
Sbjct: 272 LIPFVLIIYCYAAIIRTL-NAYDHRWLWYVKASL-LILVIFTICFAPSNIILIIHHANYY 329
Query: 250 ICGESPAWRIYV--TLLSTLNSCVDPFVYYFSS 280
+ IY+ L +LNSC+DPF+Y+ S
Sbjct: 330 YNNTDGLYFIYLIALCLGSLNSCLDPFLYFLMS 362
>gi|89353783 coagulation factor II (thrombin) receptor-like 3
precursor [Homo sapiens]
Length = 385
Score = 111 bits (277), Expect = 1e-24
Identities = 92/274 (33%), Positives = 135/274 (49%), Gaps = 15/274 (5%)
Query: 19 SVYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMVEAANG 78
++Y L +VGLP N LAL V + R P + LL+NL A+DLLL L LP R+ G
Sbjct: 82 ALYGLVLVVGLPANGLALWVLATQAPRLPSTM--LLMNLAAADLLLALALPPRIAYHLRG 139
Query: 79 MHWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLWYKT-RPRLGQAGLVSV 137
WP C L+ + +Y + L LAAVS++R+L++ HPL + R R GL +
Sbjct: 140 QRWPFGEAACRLATAALYGHMYGSVLLLAAVSLDRYLALVHPLRARALRGRRLALGL-CM 198
Query: 138 ACWLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKD-QLAILLPVRLEMAVVLFVVP 196
A WL+A+A + + + ++ S C+ D Q + P +A++ +P
Sbjct: 199 AAWLMAAALALPLTLQRQTFRLARSDRV--LCHDALPLDAQASHWQPAFTCLALLGCFLP 256
Query: 197 LIITSYCYSRLVWILGRGGSHRRQRRVAGLLAATLLNFLVCFGPYNVSHVVGYICGESPA 256
L+ CY + L G RR L A L + + F P N+ ++ Y A
Sbjct: 257 LLAMLLCYGATLHTLAASG--RRYGHALRLTAVVLASAVAFFVPSNLLLLLHYSDPSPSA 314
Query: 257 W----RIYV--TLLSTLNSCVDPFVYYFSSSGFQ 284
W YV LSTLNSCVDPF+YY+ S+ F+
Sbjct: 315 WGNLYGAYVPSLALSTLNSCVDPFIYYYVSAEFR 348
>gi|241982708 G-protein coupled purinergic receptor P2Y5 [Homo
sapiens]
Length = 344
Score = 110 bits (274), Expect = 2e-24
Identities = 82/284 (28%), Positives = 140/284 (49%), Gaps = 26/284 (9%)
Query: 20 VYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMVEAANGM 79
++ + F++GL N +A+ +F+ L+ R ++NL SDLL + LPFR+
Sbjct: 23 MFSMVFVLGLISNCVAIYIFICVLKVRNETT-TYMINLAMSDLLFVFTLPFRIFYFTT-R 80
Query: 80 HWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLWYKTRPRLGQAGLVSVAC 139
+WP +LC +S +F+T +Y + LFL +S++RFL++ +P KT A +V
Sbjct: 81 NWPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKSKTLRTKRNAKIVCTGV 140
Query: 140 WL-LASAHCSVVYVIEFSGDISHSQGTNGT--CYLEFRKDQLAILLP-VRLEMAVVLFVV 195
WL + V+V +HSQG N + C+ F + L + + + +V F +
Sbjct: 141 WLTVIGGSAPAVFV-----QSTHSQGNNASEACFENFPEATWKTYLSRIVIFIEIVGFFI 195
Query: 196 PLIITSYCYSRLVWILGRGGSHRRQR----RVAGLLAATLLNFLVCFGPYNVSHVVGYI- 250
PLI+ C S ++ L + + R + +V ++ L+ F CF PYN++ ++ +
Sbjct: 196 PLILNVTCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFVPYNINLILYSLV 255
Query: 251 -------CGESPAWRIY--VTL-LSTLNSCVDPFVYYFSSSGFQ 284
C A R +TL ++ N C DP VYYF+S Q
Sbjct: 256 RTQTFVNCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQ 299
>gi|241982706 G-protein coupled purinergic receptor P2Y5 [Homo
sapiens]
Length = 344
Score = 110 bits (274), Expect = 2e-24
Identities = 82/284 (28%), Positives = 140/284 (49%), Gaps = 26/284 (9%)
Query: 20 VYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMVEAANGM 79
++ + F++GL N +A+ +F+ L+ R ++NL SDLL + LPFR+
Sbjct: 23 MFSMVFVLGLISNCVAIYIFICVLKVRNETT-TYMINLAMSDLLFVFTLPFRIFYFTT-R 80
Query: 80 HWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLWYKTRPRLGQAGLVSVAC 139
+WP +LC +S +F+T +Y + LFL +S++RFL++ +P KT A +V
Sbjct: 81 NWPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKSKTLRTKRNAKIVCTGV 140
Query: 140 WL-LASAHCSVVYVIEFSGDISHSQGTNGT--CYLEFRKDQLAILLP-VRLEMAVVLFVV 195
WL + V+V +HSQG N + C+ F + L + + + +V F +
Sbjct: 141 WLTVIGGSAPAVFV-----QSTHSQGNNASEACFENFPEATWKTYLSRIVIFIEIVGFFI 195
Query: 196 PLIITSYCYSRLVWILGRGGSHRRQR----RVAGLLAATLLNFLVCFGPYNVSHVVGYI- 250
PLI+ C S ++ L + + R + +V ++ L+ F CF PYN++ ++ +
Sbjct: 196 PLILNVTCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFVPYNINLILYSLV 255
Query: 251 -------CGESPAWRIY--VTL-LSTLNSCVDPFVYYFSSSGFQ 284
C A R +TL ++ N C DP VYYF+S Q
Sbjct: 256 RTQTFVNCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQ 299
>gi|33695113 G-protein coupled purinergic receptor P2Y5 [Homo
sapiens]
Length = 344
Score = 110 bits (274), Expect = 2e-24
Identities = 82/284 (28%), Positives = 140/284 (49%), Gaps = 26/284 (9%)
Query: 20 VYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMVEAANGM 79
++ + F++GL N +A+ +F+ L+ R ++NL SDLL + LPFR+
Sbjct: 23 MFSMVFVLGLISNCVAIYIFICVLKVRNETT-TYMINLAMSDLLFVFTLPFRIFYFTT-R 80
Query: 80 HWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLWYKTRPRLGQAGLVSVAC 139
+WP +LC +S +F+T +Y + LFL +S++RFL++ +P KT A +V
Sbjct: 81 NWPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKSKTLRTKRNAKIVCTGV 140
Query: 140 WL-LASAHCSVVYVIEFSGDISHSQGTNGT--CYLEFRKDQLAILLP-VRLEMAVVLFVV 195
WL + V+V +HSQG N + C+ F + L + + + +V F +
Sbjct: 141 WLTVIGGSAPAVFV-----QSTHSQGNNASEACFENFPEATWKTYLSRIVIFIEIVGFFI 195
Query: 196 PLIITSYCYSRLVWILGRGGSHRRQR----RVAGLLAATLLNFLVCFGPYNVSHVVGYI- 250
PLI+ C S ++ L + + R + +V ++ L+ F CF PYN++ ++ +
Sbjct: 196 PLILNVTCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFVPYNINLILYSLV 255
Query: 251 -------CGESPAWRIY--VTL-LSTLNSCVDPFVYYFSSSGFQ 284
C A R +TL ++ N C DP VYYF+S Q
Sbjct: 256 RTQTFVNCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQ 299
>gi|4505561 pyrimidinergic receptor P2Y4 [Homo sapiens]
Length = 365
Score = 108 bits (270), Expect = 7e-24
Identities = 87/295 (29%), Positives = 143/295 (48%), Gaps = 33/295 (11%)
Query: 21 YLLTFLVGLPLNLLALVVFVGKLQRRPV-AVDVLLLNLTASDLLLLLFLPFRMVEAANGM 79
Y + F++GL LN L +F+ +L RP A + +L SD L +L LP + A
Sbjct: 42 YAVVFVLGLGLNAPTLWLFIFRL--RPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHN 99
Query: 80 HWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPL----WYKTRPRLGQAGLV 135
HWP +C F+F+ +Y + LFL +S+ R+L + HPL W RPRL AGL+
Sbjct: 100 HWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRW--GRPRL--AGLL 155
Query: 136 SVACWLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQLAILLPVRLEMAVVLFVV 195
+A WL+ A C V + + + ++GT C+ R ++ + + +LF V
Sbjct: 156 CLAVWLVV-AGCLVPNLFFVT---TSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGV 211
Query: 196 PLIITSYCYSRLVWILGR--GGSHRRQRRVAGL--LAATLLNFLVCFGPYNVSHVVGYIC 251
P ++T CY + L + GS + R+ L +A L F VCF P++++ + Y+
Sbjct: 212 PCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLA 271
Query: 252 GESPAWRIYVTL----------LSTLNSCVDPFVYYFSSSGFQADFHELLRRLCG 296
A + + L++ NSC+DP +Y + ++ LR+LCG
Sbjct: 272 RLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQ----LRQLCG 322
>gi|29029612 pyrimidinergic receptor P2Y6 [Homo sapiens]
Length = 328
Score = 107 bits (268), Expect = 1e-23
Identities = 82/301 (27%), Positives = 130/301 (43%), Gaps = 31/301 (10%)
Query: 20 VYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMVEAANGM 79
VY GLPLN+ ++ + +R V LNL +DLL LP + A G
Sbjct: 32 VYSAVLAAGLPLNI-CVITQICTSRRALTRTAVYTLNLALADLLYACSLPLLIYNYAQGD 90
Query: 80 HWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPL--WYKTRPRLGQAGLVSV 137
HWP C L F+F+ ++ + LFL +S +R+L + HPL W+K R A LV V
Sbjct: 91 HWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRA-AWLVCV 149
Query: 138 ACWLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQLAI-LLPVRLEMAVVLFVVP 196
A WL + C + +G Q CY + LA +P + + V+ F++P
Sbjct: 150 AVWLAVTTQCLPTAIFAATG----IQRNRTVCY-DLSPPALATHYMPYGMALTVIGFLLP 204
Query: 197 LIITSYCYSRLVWILGRGG------SHRRQRRVAGLLAATLLNFLVCFGPYNVSHVVGYI 250
CY L L R + R+ + A + F + F P++++
Sbjct: 205 FAALLACYCLLACRLCRQDGPAEPVAQERRGKAARMAVVVAAAFAISFLPFHITKTAYLA 264
Query: 251 CGESPAWRIYVTLL-------------STLNSCVDPFVYYFSSSGFQADFHELLRRLCGL 297
+P + T+L ++ NS +DP ++YF+ F+ HELL++L
Sbjct: 265 VRSTPG--VPCTVLEAFAAAYKGTRPFASANSVLDPILFYFTQKKFRRRPHELLQKLTAK 322
Query: 298 W 298
W
Sbjct: 323 W 323
>gi|29029610 pyrimidinergic receptor P2Y6 [Homo sapiens]
Length = 328
Score = 107 bits (268), Expect = 1e-23
Identities = 82/301 (27%), Positives = 130/301 (43%), Gaps = 31/301 (10%)
Query: 20 VYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMVEAANGM 79
VY GLPLN+ ++ + +R V LNL +DLL LP + A G
Sbjct: 32 VYSAVLAAGLPLNI-CVITQICTSRRALTRTAVYTLNLALADLLYACSLPLLIYNYAQGD 90
Query: 80 HWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPL--WYKTRPRLGQAGLVSV 137
HWP C L F+F+ ++ + LFL +S +R+L + HPL W+K R A LV V
Sbjct: 91 HWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRA-AWLVCV 149
Query: 138 ACWLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQLAI-LLPVRLEMAVVLFVVP 196
A WL + C + +G Q CY + LA +P + + V+ F++P
Sbjct: 150 AVWLAVTTQCLPTAIFAATG----IQRNRTVCY-DLSPPALATHYMPYGMALTVIGFLLP 204
Query: 197 LIITSYCYSRLVWILGRGG------SHRRQRRVAGLLAATLLNFLVCFGPYNVSHVVGYI 250
CY L L R + R+ + A + F + F P++++
Sbjct: 205 FAALLACYCLLACRLCRQDGPAEPVAQERRGKAARMAVVVAAAFAISFLPFHITKTAYLA 264
Query: 251 CGESPAWRIYVTLL-------------STLNSCVDPFVYYFSSSGFQADFHELLRRLCGL 297
+P + T+L ++ NS +DP ++YF+ F+ HELL++L
Sbjct: 265 VRSTPG--VPCTVLEAFAAAYKGTRPFASANSVLDPILFYFTQKKFRRRPHELLQKLTAK 322
Query: 298 W 298
W
Sbjct: 323 W 323
>gi|29029608 pyrimidinergic receptor P2Y6 [Homo sapiens]
Length = 328
Score = 107 bits (268), Expect = 1e-23
Identities = 82/301 (27%), Positives = 130/301 (43%), Gaps = 31/301 (10%)
Query: 20 VYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMVEAANGM 79
VY GLPLN+ ++ + +R V LNL +DLL LP + A G
Sbjct: 32 VYSAVLAAGLPLNI-CVITQICTSRRALTRTAVYTLNLALADLLYACSLPLLIYNYAQGD 90
Query: 80 HWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPL--WYKTRPRLGQAGLVSV 137
HWP C L F+F+ ++ + LFL +S +R+L + HPL W+K R A LV V
Sbjct: 91 HWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRA-AWLVCV 149
Query: 138 ACWLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQLAI-LLPVRLEMAVVLFVVP 196
A WL + C + +G Q CY + LA +P + + V+ F++P
Sbjct: 150 AVWLAVTTQCLPTAIFAATG----IQRNRTVCY-DLSPPALATHYMPYGMALTVIGFLLP 204
Query: 197 LIITSYCYSRLVWILGRGG------SHRRQRRVAGLLAATLLNFLVCFGPYNVSHVVGYI 250
CY L L R + R+ + A + F + F P++++
Sbjct: 205 FAALLACYCLLACRLCRQDGPAEPVAQERRGKAARMAVVVAAAFAISFLPFHITKTAYLA 264
Query: 251 CGESPAWRIYVTLL-------------STLNSCVDPFVYYFSSSGFQADFHELLRRLCGL 297
+P + T+L ++ NS +DP ++YF+ F+ HELL++L
Sbjct: 265 VRSTPG--VPCTVLEAFAAAYKGTRPFASANSVLDPILFYFTQKKFRRRPHELLQKLTAK 322
Query: 298 W 298
W
Sbjct: 323 W 323
>gi|4758864 pyrimidinergic receptor P2Y6 [Homo sapiens]
Length = 328
Score = 107 bits (268), Expect = 1e-23
Identities = 82/301 (27%), Positives = 130/301 (43%), Gaps = 31/301 (10%)
Query: 20 VYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMVEAANGM 79
VY GLPLN+ ++ + +R V LNL +DLL LP + A G
Sbjct: 32 VYSAVLAAGLPLNI-CVITQICTSRRALTRTAVYTLNLALADLLYACSLPLLIYNYAQGD 90
Query: 80 HWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPL--WYKTRPRLGQAGLVSV 137
HWP C L F+F+ ++ + LFL +S +R+L + HPL W+K R A LV V
Sbjct: 91 HWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRA-AWLVCV 149
Query: 138 ACWLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQLAI-LLPVRLEMAVVLFVVP 196
A WL + C + +G Q CY + LA +P + + V+ F++P
Sbjct: 150 AVWLAVTTQCLPTAIFAATG----IQRNRTVCY-DLSPPALATHYMPYGMALTVIGFLLP 204
Query: 197 LIITSYCYSRLVWILGRGG------SHRRQRRVAGLLAATLLNFLVCFGPYNVSHVVGYI 250
CY L L R + R+ + A + F + F P++++
Sbjct: 205 FAALLACYCLLACRLCRQDGPAEPVAQERRGKAARMAVVVAAAFAISFLPFHITKTAYLA 264
Query: 251 CGESPAWRIYVTLL-------------STLNSCVDPFVYYFSSSGFQADFHELLRRLCGL 297
+P + T+L ++ NS +DP ++YF+ F+ HELL++L
Sbjct: 265 VRSTPG--VPCTVLEAFAAAYKGTRPFASANSVLDPILFYFTQKKFRRRPHELLQKLTAK 322
Query: 298 W 298
W
Sbjct: 323 W 323
>gi|4885057 apelin receptor [Homo sapiens]
Length = 380
Score = 106 bits (265), Expect = 3e-23
Identities = 85/341 (24%), Positives = 149/341 (43%), Gaps = 41/341 (12%)
Query: 19 SVYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMVEAANG 78
++Y+L FL+G N L L + + + D+ + +L +DL ++ LP
Sbjct: 33 AIYMLVFLLGTTGNGLVLWTVFRSSREKRRSADIFIASLAVADLTFVVTLPLWATYTYRD 92
Query: 79 MHWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLWYKTRPRLGQAGLVSVA 138
WP C LS ++ F +Y + L +S +R+L++ P+ R RL +G V+ A
Sbjct: 93 YDWPFGTFFCKLSSYLIFVNMYASVFCLTGLSFDRYLAIVRPV-ANARLRLRVSGAVATA 151
Query: 139 -CWLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFR-----KDQLAILLPVRLEMAVVL 192
W+LA+ V V+ +GD+ ++ T CY+++ + A + + + V
Sbjct: 152 VLWVLAALLAMPVMVLRTTGDLENT--TKVQCYMDYSMVATVSSEWAWEVGLGVSSTTVG 209
Query: 193 FVVPLIITSYCYSRLVWILG------RGGSHRRQRRVAGLLAATLLNFLVCFGPYNVSHV 246
FVVP I CY + + R R++RR+ ++ ++ F +C+ PY++
Sbjct: 210 FVVPFTIMLTCYFFIAQTIAGHFRKERIEGLRKRRRLLSIIVVLVVTFALCWMPYHLVKT 269
Query: 247 VGYICGESPAWRI-----------YVTLLSTLNSCVDPFVYYFSSSGFQADFHELLRRLC 295
+ Y+ G W Y T +S +NSC++PF+Y F F+ +L C
Sbjct: 270 L-YMLGSLLHWPCDFDLFLMNIFPYCTCISYVNSCLNPFLYAFFDPRFRQACTSML--CC 326
Query: 296 GLWGQWQQESSMELKEQKGGEEQRADRPAERKTSEHSQGCG 336
G Q GE+ + +S HSQG G
Sbjct: 327 G------QSRCAGTSHSSSGEKSAS------YSSGHSQGPG 355
>gi|148225857 G protein-coupled receptor 34 [Homo sapiens]
Length = 381
Score = 104 bits (260), Expect = 1e-22
Identities = 79/291 (27%), Positives = 138/291 (47%), Gaps = 25/291 (8%)
Query: 21 YLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMVEAANGMH 80
Y + F+VGL N++AL VF+G + R+ ++ + LLN+ +DLLL+ LPFR++ N
Sbjct: 61 YSVIFIVGLVGNIIALYVFLG-IHRKRNSIQIYLLNVAIADLLLIFCLPFRIMYHINQNK 119
Query: 81 WPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLWYKTRPRLGQAGLVSVACW 140
W L ILC + G +F+ +Y++ + L +S++R++ + + + Q+ V W
Sbjct: 120 WTLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRKAITTKQSIYVCCIVW 179
Query: 141 LLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQLAILLPVRLEMAVVLFVVPLIIT 200
+LA + ++ G N T +R A + + VV+F + ++
Sbjct: 180 MLALGGFLTMIILTLK-----KGGHNSTMCFHYRDKHNAKGEAIFNFILVVMFWLIFLLI 234
Query: 201 SYCYSRLVWILGRGGSHRRQRRVAGLLAAT-------LLNFLVCFGPYNVSHVVGYICGE 253
Y ++ L R R + +G A T L+ F +CF PY+ + YI +
Sbjct: 235 ILSYIKIGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFVPYHAFRFI-YISSQ 293
Query: 254 ----SPAWRIYV-------TLLSTLNSCVDPFVYYFSSSGFQADFHELLRR 293
S W+ V +LS+ NSC+DP +Y+ SS + +LL R
Sbjct: 294 LNVSSCYWKEIVHKTNEIMLVLSSFNSCLDPVMYFLMSSNIRKIMCQLLFR 344
>gi|4885319 G protein-coupled receptor 34 [Homo sapiens]
Length = 381
Score = 104 bits (260), Expect = 1e-22
Identities = 79/291 (27%), Positives = 138/291 (47%), Gaps = 25/291 (8%)
Query: 21 YLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMVEAANGMH 80
Y + F+VGL N++AL VF+G + R+ ++ + LLN+ +DLLL+ LPFR++ N
Sbjct: 61 YSVIFIVGLVGNIIALYVFLG-IHRKRNSIQIYLLNVAIADLLLIFCLPFRIMYHINQNK 119
Query: 81 WPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLWYKTRPRLGQAGLVSVACW 140
W L ILC + G +F+ +Y++ + L +S++R++ + + + Q+ V W
Sbjct: 120 WTLGVILCKVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRKAITTKQSIYVCCIVW 179
Query: 141 LLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQLAILLPVRLEMAVVLFVVPLIIT 200
+LA + ++ G N T +R A + + VV+F + ++
Sbjct: 180 MLALGGFLTMIILTLK-----KGGHNSTMCFHYRDKHNAKGEAIFNFILVVMFWLIFLLI 234
Query: 201 SYCYSRLVWILGRGGSHRRQRRVAGLLAAT-------LLNFLVCFGPYNVSHVVGYICGE 253
Y ++ L R R + +G A T L+ F +CF PY+ + YI +
Sbjct: 235 ILSYIKIGKNLLRISKRRSKFPNSGKYATTARNSFIVLIIFTICFVPYHAFRFI-YISSQ 293
Query: 254 ----SPAWRIYV-------TLLSTLNSCVDPFVYYFSSSGFQADFHELLRR 293
S W+ V +LS+ NSC+DP +Y+ SS + +LL R
Sbjct: 294 LNVSSCYWKEIVHKTNEIMLVLSSFNSCLDPVMYFLMSSNIRKIMCQLLFR 344
>gi|4557861 somatostatin receptor 3 [Homo sapiens]
Length = 418
Score = 103 bits (256), Expect = 3e-22
Identities = 100/367 (27%), Positives = 165/367 (44%), Gaps = 39/367 (10%)
Query: 1 MDTGPDQSYFSGNHWFVFSVYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTAS 60
+ GP + + + + VYL+ +VGL N L + V + + P +V +LNL +
Sbjct: 31 VSAGPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVL-RHTASPSVTNVYILNLALA 89
Query: 61 DLLLLLFLPFRMVEAANGMHWPLPFILCPL----SGFIFFTTIYLTALFLAAVSIERFLS 116
D L +L LPF + A +WP ++C L G FT+I+ L +S++R+L+
Sbjct: 90 DELFMLGLPFLAAQNALS-YWPFGSLMCRLVMAVDGINQFTSIFC----LTVMSVDRYLA 144
Query: 117 VAHPLWYKTRPRLGQAGLVSVACWLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKD 176
V HP A VS A W+ ++ V+ V+ FSG +G + TC++++ +
Sbjct: 145 VVHPTRSARWRTAPVARTVSAAVWVASAV--VVLPVVVFSGV---PRGMS-TCHMQWPEP 198
Query: 177 QLAILLPVRLEMAVVLFVVPLIITSYCY----------SRLVWILGRGGSHRRQRRVAGL 226
A + A + F PL++ CY R VW R +RRV +
Sbjct: 199 AAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRVWAPSCQRRRRSERRVTRM 258
Query: 227 LAATLLNFLVCFGPYNVSHVVGYIC--GESPAW---RIYVTLLSTLNSCVDPFVYYFSSS 281
+ A + F++C+ P+ V ++V +C E PA+ V L NSC +P +Y F S
Sbjct: 259 VVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSY 318
Query: 282 GFQADFHELLRRLCGLWGQWQ------QESSMELKEQKGGEEQRADRPAERKTSEHSQ-- 333
F+ F +L R + +++ E +E++ GEE R + SQ
Sbjct: 319 RFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEESREGGKGKEMNGRVSQIT 378
Query: 334 GCGTGGQ 340
GT GQ
Sbjct: 379 QPGTSGQ 385
>gi|148228829 G protein-coupled receptor 1 [Homo sapiens]
Length = 355
Score = 103 bits (256), Expect = 3e-22
Identities = 81/317 (25%), Positives = 138/317 (43%), Gaps = 19/317 (5%)
Query: 14 HWFVFSVYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMV 73
HW +Y L F++G+P N A+V++ + + + LNL +D + LLFLP +
Sbjct: 38 HWVSLVLYCLAFVLGIPGN--AIVIWFTGFKWKKTVTTLWFLNLAIADFIFLLFLPLYIS 95
Query: 74 EAANGMHWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLWYKTRPRLGQAG 133
A HWP LC + F ++ + FL +S++ ++ + HP+ L +
Sbjct: 96 YVAMNFHWPFGIWLCKANSFTAQLNMFASVFFLTVISLDHYIHLIHPVLSHRHRTLKNSL 155
Query: 134 LVSVACWLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQLAILLPVRLEMAVVLF 193
+V + WLLAS + F + + T CY F+K + L + V F
Sbjct: 156 IVIIFIWLLASLIGGP--ALYFRDTVEFNNHT--LCYNNFQKHDPDLTLIRHHVLTWVKF 211
Query: 194 VV----PLIITSYCYSRLVWILGRGGSHRRQRRVAGLLAATLLNFLVCFGPYNV------ 243
++ PL+ S CY L++ + + R +L ++ F+VC+ PY++
Sbjct: 212 IIGYLFPLLTMSICYLCLIFKVKKRSILISSRHFWTIL-VVVVAFVVCWTPYHLFSIWEL 270
Query: 244 -SHVVGYICGESPAWRIYVTLLSTLNSCVDPFVYYFSSSGFQADFHELLRRLCGLWGQWQ 302
H Y A T L+ LNSC++P +Y S FQA F + + + W+
Sbjct: 271 TIHHNSYSHHVMQAGIPLSTGLAFLNSCLNPILYVLISKKFQARFRSSVAEIL-KYTLWE 329
Query: 303 QESSMELKEQKGGEEQR 319
S + EQ E +
Sbjct: 330 VSCSGTVSEQLRNSETK 346
>gi|36951012 G protein-coupled receptor 1 [Homo sapiens]
Length = 355
Score = 103 bits (256), Expect = 3e-22
Identities = 81/317 (25%), Positives = 138/317 (43%), Gaps = 19/317 (5%)
Query: 14 HWFVFSVYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMV 73
HW +Y L F++G+P N A+V++ + + + LNL +D + LLFLP +
Sbjct: 38 HWVSLVLYCLAFVLGIPGN--AIVIWFTGFKWKKTVTTLWFLNLAIADFIFLLFLPLYIS 95
Query: 74 EAANGMHWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLWYKTRPRLGQAG 133
A HWP LC + F ++ + FL +S++ ++ + HP+ L +
Sbjct: 96 YVAMNFHWPFGIWLCKANSFTAQLNMFASVFFLTVISLDHYIHLIHPVLSHRHRTLKNSL 155
Query: 134 LVSVACWLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQLAILLPVRLEMAVVLF 193
+V + WLLAS + F + + T CY F+K + L + V F
Sbjct: 156 IVIIFIWLLASLIGGP--ALYFRDTVEFNNHT--LCYNNFQKHDPDLTLIRHHVLTWVKF 211
Query: 194 VV----PLIITSYCYSRLVWILGRGGSHRRQRRVAGLLAATLLNFLVCFGPYNV------ 243
++ PL+ S CY L++ + + R +L ++ F+VC+ PY++
Sbjct: 212 IIGYLFPLLTMSICYLCLIFKVKKRSILISSRHFWTIL-VVVVAFVVCWTPYHLFSIWEL 270
Query: 244 -SHVVGYICGESPAWRIYVTLLSTLNSCVDPFVYYFSSSGFQADFHELLRRLCGLWGQWQ 302
H Y A T L+ LNSC++P +Y S FQA F + + + W+
Sbjct: 271 TIHHNSYSHHVMQAGIPLSTGLAFLNSCLNPILYVLISKKFQARFRSSVAEIL-KYTLWE 329
Query: 303 QESSMELKEQKGGEEQR 319
S + EQ E +
Sbjct: 330 VSCSGTVSEQLRNSETK 346
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.141 0.452
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,338,851
Number of Sequences: 37866
Number of extensions: 572913
Number of successful extensions: 3405
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 331
Number of HSP's successfully gapped in prelim test: 219
Number of HSP's that attempted gapping in prelim test: 2421
Number of HSP's gapped (non-prelim): 666
length of query: 346
length of database: 18,247,518
effective HSP length: 103
effective length of query: 243
effective length of database: 14,347,320
effective search space: 3486398760
effective search space used: 3486398760
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.