Guide to the Human Genome
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Search of human proteins with 13375872

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13375872 queuine tRNA-ribosyltransferase domain containing 1
[Homo sapiens]
         (415 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13375872 queuine tRNA-ribosyltransferase domain containing 1 ...   845   0.0  
gi|13654276 queuine tRNA-ribosyltransferase 1 [Homo sapiens]           96   6e-20
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa...    33   0.48 
gi|106879204 exocyst complex component 3-like [Homo sapiens]           32   1.1  
gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens]           31   1.8  
gi|7705555 iroquois homeobox 4 [Homo sapiens]                          31   1.8  
gi|53829376 plakophilin 4 isoform b [Homo sapiens]                     29   6.9  
gi|53829374 plakophilin 4 isoform a [Homo sapiens]                     29   6.9  
gi|217416452 dynein, axonemal, intermediate polypeptide 2 [Homo ...    29   6.9  

>gi|13375872 queuine tRNA-ribosyltransferase domain containing 1
           [Homo sapiens]
          Length = 415

 Score =  845 bits (2182), Expect = 0.0
 Identities = 415/415 (100%), Positives = 415/415 (100%)

Query: 1   MKLSLTKVVNGCRLGKIKNLGKTGDHTMDIPGCLLYTKTGSAPHLTHHTLHNIHGVPAMA 60
           MKLSLTKVVNGCRLGKIKNLGKTGDHTMDIPGCLLYTKTGSAPHLTHHTLHNIHGVPAMA
Sbjct: 1   MKLSLTKVVNGCRLGKIKNLGKTGDHTMDIPGCLLYTKTGSAPHLTHHTLHNIHGVPAMA 60

Query: 61  QLTLSSLAEHHEVLTEYKEGVGKFIGMPESLLYCSLHDPVSPCPAGYVTNKSVSVWSVAG 120
           QLTLSSLAEHHEVLTEYKEGVGKFIGMPESLLYCSLHDPVSPCPAGYVTNKSVSVWSVAG
Sbjct: 61  QLTLSSLAEHHEVLTEYKEGVGKFIGMPESLLYCSLHDPVSPCPAGYVTNKSVSVWSVAG 120

Query: 121 RVEMTVSKFMAIQKALQPDWFQCLSDGEVSCKEATSIKRVRKSVDRSLLFLDNCLRLQEE 180
           RVEMTVSKFMAIQKALQPDWFQCLSDGEVSCKEATSIKRVRKSVDRSLLFLDNCLRLQEE
Sbjct: 121 RVEMTVSKFMAIQKALQPDWFQCLSDGEVSCKEATSIKRVRKSVDRSLLFLDNCLRLQEE 180

Query: 181 SEVLQKSVIIGVIEGGDVMEERLRSARETAKRPVGGFLLDGFQGNPTTLEARLRLLSSVT 240
           SEVLQKSVIIGVIEGGDVMEERLRSARETAKRPVGGFLLDGFQGNPTTLEARLRLLSSVT
Sbjct: 181 SEVLQKSVIIGVIEGGDVMEERLRSARETAKRPVGGFLLDGFQGNPTTLEARLRLLSSVT 240

Query: 241 AELPEDKPRLISGVSRPDEVLECIERGVDLFESFFPYQVTERGCALTFSFDYQPNPEETL 300
           AELPEDKPRLISGVSRPDEVLECIERGVDLFESFFPYQVTERGCALTFSFDYQPNPEETL
Sbjct: 241 AELPEDKPRLISGVSRPDEVLECIERGVDLFESFFPYQVTERGCALTFSFDYQPNPEETL 300

Query: 301 LQQNGTQEEIKCMDQIKKIETTGCNQEITSFEINLKEKKYQEDFNPLVRGCSCYCCKNHT 360
           LQQNGTQEEIKCMDQIKKIETTGCNQEITSFEINLKEKKYQEDFNPLVRGCSCYCCKNHT
Sbjct: 301 LQQNGTQEEIKCMDQIKKIETTGCNQEITSFEINLKEKKYQEDFNPLVRGCSCYCCKNHT 360

Query: 361 RAYIHHLLVTNELLAGVLLMMHNFEHYFGFFHYIREALKSDKLAQLKELIHRQAS 415
           RAYIHHLLVTNELLAGVLLMMHNFEHYFGFFHYIREALKSDKLAQLKELIHRQAS
Sbjct: 361 RAYIHHLLVTNELLAGVLLMMHNFEHYFGFFHYIREALKSDKLAQLKELIHRQAS 415


>gi|13654276 queuine tRNA-ribosyltransferase 1 [Homo sapiens]
          Length = 403

 Score = 95.9 bits (237), Expect = 6e-20
 Identities = 82/328 (25%), Positives = 139/328 (42%), Gaps = 51/328 (15%)

Query: 74  LTEYKEGVGKFIGMPESLLYCSL-HDPVSPCPAGYVTNKSVSVWSVAGRVEMTVS--KFM 130
           L +   G+  F+  P +LL  S     VS      VT + V   S     E  +S  K +
Sbjct: 85  LIQKANGLHGFMNWPHNLLTDSGGFQMVSLVSLSEVTEEGVRFRSPYDGNETLLSPEKSV 144

Query: 131 AIQKALQPDWFQCLSDGEVSCKEATSIKRVRKSVDRSLLFLDNCLRLQEESEVLQKSVII 190
            IQ AL  D    L D   S     +  RV +++ RS+ +LD C+   +  +   K  + 
Sbjct: 145 QIQNALGSDIIMQLDDVVSS---TVTGPRVEEAMYRSIRWLDRCIAAHQRPD---KQNLF 198

Query: 191 GVIEGGDVMEERLRSARETAKRPVGGFLLDGFQGNPTTLEARLRLLSSVTAELPEDKPRL 250
            +I+GG   + R     E  KR V GF + G  G  +  +   R+++  T+ LP+DKPR 
Sbjct: 199 AIIQGGLDADLRATCLEEMTKRDVPGFAIGGLSGGESKSQF-WRMVALSTSRLPKDKPRY 257

Query: 251 ISGVSRPDEVLECIERGVDLFESFFPYQVTERGCALTFSFDYQPNPEETLLQQNGTQEEI 310
           + GV    +++ C+  G D+F+  FP +    G AL                        
Sbjct: 258 LMGVGYATDLVVCVALGCDMFDCVFPTRTARFGSAL------------------------ 293

Query: 311 KCMDQIKKIETTGCNQEITSFEINLKEKKYQEDFNPLVRGCSCYCCKNHTRAYIHHLLVT 370
                            + +  + L++K +++DF P+   C+C  C+ H+RA++H LL +
Sbjct: 294 -----------------VPTGNLQLRKKVFEKDFGPIDPECTCPTCQKHSRAFLHALLHS 336

Query: 371 NELLAGVLLMMHNFEHYFGFFHYIREAL 398
           +   A   L +HN  +       +R ++
Sbjct: 337 DNTAALHHLTVHNIAYQLQLMSAVRTSI 364


>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
           sapiens]
          Length = 1954

 Score = 33.1 bits (74), Expect = 0.48
 Identities = 30/105 (28%), Positives = 50/105 (47%), Gaps = 21/105 (20%)

Query: 245 EDKPRLISG-VSRPDEVLECIERGVDLFESFFPYQVTERGCALTFSFDYQPNPEETLLQQ 303
           E+ PRL +  +   DE+ E  + G++ F+ FFP +          S   +  P++     
Sbjct: 9   EELPRLFAEEMENEDEMSEEEDGGLEAFDDFFPVE--------PVSLPKKKKPKKL---- 56

Query: 304 NGTQEEIKCMDQIKKIETTGCNQEITSFEINLKEKKYQE--DFNP 346
               +E KC  + KK E  G N E++  E +L+EK   E  D++P
Sbjct: 57  ----KENKCKGKRKKKE--GSNDELSENEEDLEEKSESEGSDYSP 95


>gi|106879204 exocyst complex component 3-like [Homo sapiens]
          Length = 746

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 40/176 (22%), Positives = 64/176 (36%), Gaps = 17/176 (9%)

Query: 94  CSLHDPVSPCPAGYVTNKSVSVWSVAGRVEMTVSKFMAIQKALQPDWFQCLSDGEVSCKE 153
           CSL   +      Y+      VW +A  +E+      A+ +A      + L  G     +
Sbjct: 62  CSLESRLKSVMQSYLEGVQTGVWQLAQAIEVVQGTREALSQA------RGLLQGMSQALQ 115

Query: 154 ATSIKRVRKSVDRSLLFLDNCL-RLQEESEVLQKSVIIGVIEGGDVME-----ERLRSAR 207
                R R +  + L  L + L RL+     +  +  +  I+G   +E       L   R
Sbjct: 116 TLEPLRERVAQHKQLQALSHLLPRLRAVPAAVSHTQTL--IDGQQFLEAYVSLRELEQLR 173

Query: 208 ETAKRPVGGFLLDGFQGNPTTLEA---RLRLLSSVTAELPEDKPRLISGVSRPDEV 260
           E    P+GG  L  FQG     EA    +   +    +L  + P L+    R  EV
Sbjct: 174 EDTWAPLGGLELPVFQGLDLLFEALGQAVEAAAGAAGKLAREDPALLVAAVRVAEV 229


>gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens]
          Length = 1251

 Score = 31.2 bits (69), Expect = 1.8
 Identities = 27/118 (22%), Positives = 46/118 (38%), Gaps = 14/118 (11%)

Query: 280 TERGCALTFSFDYQPNPEETLLQQNGTQEEIKCMDQIKKIETTGCNQEI----------T 329
           TER    TF  D QPN E      + T++E+       + E    N+E            
Sbjct: 3   TERDSETTFDEDSQPNDEVVPYSDDETEDELDDQGSAVEPEQNRVNREAEENREPFRKEC 62

Query: 330 SFEINLKEKKYQEDFNPLVRGCSCYCCKNHTRAYIHHLLVTNELLAGVLLMMHNFEHY 387
           ++++   ++KY E   P        C K     Y ++ + T +  A   + M+ FE +
Sbjct: 63  TWQVKANDRKYHE--QPHFMNTKFLCIKE--SKYANNAIKTYKYNAFTFIPMNLFEQF 116


>gi|7705555 iroquois homeobox 4 [Homo sapiens]
          Length = 519

 Score = 31.2 bits (69), Expect = 1.8
 Identities = 24/77 (31%), Positives = 37/77 (48%), Gaps = 4/77 (5%)

Query: 177 LQEESEVLQKSVIIGVIEGGDVMEERLRSARETAKRPVGG-FLLDGFQGNPTTLEARLRL 235
           ++E S  L+ S+  G   GG  ++E L  AR   +    G   L G +G P   EA+L  
Sbjct: 297 VKEASGALRMSLAAG---GGAALDEDLERARSCLRSAAAGPEPLPGAEGGPQVCEAKLGF 353

Query: 236 LSSVTAELPEDKPRLIS 252
           + +  +   E KPR+ S
Sbjct: 354 VPAGASAGLEAKPRIWS 370


>gi|53829376 plakophilin 4 isoform b [Homo sapiens]
          Length = 1149

 Score = 29.3 bits (64), Expect = 6.9
 Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 6/70 (8%)

Query: 12  CRLGKIKNLGKTGDHTM-----DIPGCLLYTKTGSAPHLTHHTLHNIHGVPAMAQLTLSS 66
           CRLG IK+L    DH +     +  G L     G +       + N+ G+PA+ +L   S
Sbjct: 567 CRLGGIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKS 626

Query: 67  L-AEHHEVLT 75
           + AE  E++T
Sbjct: 627 IDAEVRELVT 636


>gi|53829374 plakophilin 4 isoform a [Homo sapiens]
          Length = 1192

 Score = 29.3 bits (64), Expect = 6.9
 Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 6/70 (8%)

Query: 12  CRLGKIKNLGKTGDHTM-----DIPGCLLYTKTGSAPHLTHHTLHNIHGVPAMAQLTLSS 66
           CRLG IK+L    DH +     +  G L     G +       + N+ G+PA+ +L   S
Sbjct: 567 CRLGGIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKS 626

Query: 67  L-AEHHEVLT 75
           + AE  E++T
Sbjct: 627 IDAEVRELVT 636


>gi|217416452 dynein, axonemal, intermediate polypeptide 2 [Homo
           sapiens]
          Length = 605

 Score = 29.3 bits (64), Expect = 6.9
 Identities = 17/61 (27%), Positives = 29/61 (47%), Gaps = 2/61 (3%)

Query: 289 SFDYQPNPE--ETLLQQNGTQEEIKCMDQIKKIETTGCNQEITSFEINLKEKKYQEDFNP 346
           + D  PNPE  E  +++N     I+C   + + E      E+ +  +N  E  + +D NP
Sbjct: 28  NIDIMPNPELAEQFVERNPVDTGIQCSISMSEHEANSERFEMETRGVNHVEGGWPKDVNP 87

Query: 347 L 347
           L
Sbjct: 88  L 88


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,782,182
Number of Sequences: 37866
Number of extensions: 715082
Number of successful extensions: 1735
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1728
Number of HSP's gapped (non-prelim): 11
length of query: 415
length of database: 18,247,518
effective HSP length: 105
effective length of query: 310
effective length of database: 14,271,588
effective search space: 4424192280
effective search space used: 4424192280
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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