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Search of human proteins with 48255915
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|48255915 trypsin X3 [Homo sapiens]
(241 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|48255915 trypsin X3 [Homo sapiens] 499 e-142
gi|4506145 protease, serine, 1 preproprotein [Homo sapiens] 152 2e-37
gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens] 146 2e-35
gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens] 144 5e-35
gi|4506147 protease, serine, 2 preproprotein [Homo sapiens] 142 2e-34
gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens] 124 6e-29
gi|61744424 kallikrein-related peptidase 6 isoform A preproprote... 123 1e-28
gi|4506155 kallikrein-related peptidase 6 isoform A preproprotei... 123 1e-28
gi|21327705 stratum corneum chymotryptic enzyme preproprotein [H... 122 2e-28
gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Ho... 122 2e-28
gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo ... 122 4e-28
gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo ... 122 4e-28
gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo sa... 122 4e-28
gi|4502173 prostate specific antigen isoform 1 preproprotein [Ho... 121 5e-28
gi|11496281 kallikrein 13 precursor [Homo sapiens] 120 8e-28
gi|91823048 kallikrein 14 preproprotein [Homo sapiens] 118 4e-27
gi|56606135 hypothetical protein LOC136242 [Homo sapiens] 118 5e-27
gi|22208987 kallikrein 12 isoform 2 [Homo sapiens] 117 9e-27
gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 116 2e-26
gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens] 116 2e-26
gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 116 2e-26
gi|21464127 kallikrein 8 isoform 2 [Homo sapiens] 112 3e-25
gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens] 112 3e-25
gi|71834855 prostate specific antigen isoform 4 preproprotein [H... 111 6e-25
gi|4504235 granzyme K precursor [Homo sapiens] 108 3e-24
gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprot... 108 4e-24
gi|4504875 kallikrein 1 preproprotein [Homo sapiens] 108 5e-24
gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo s... 108 5e-24
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] 108 5e-24
gi|29366812 kallikrein-related peptidase 9 [Homo sapiens] 108 5e-24
>gi|48255915 trypsin X3 [Homo sapiens]
Length = 241
Score = 499 bits (1285), Expect = e-142
Identities = 241/241 (100%), Positives = 241/241 (100%)
Query: 1 MKFILLWALLNLTVALAFNPDYTVSSTPPYLVYLKSDYLPCAGVLIHPLWVITAAHCNLP 60
MKFILLWALLNLTVALAFNPDYTVSSTPPYLVYLKSDYLPCAGVLIHPLWVITAAHCNLP
Sbjct: 1 MKFILLWALLNLTVALAFNPDYTVSSTPPYLVYLKSDYLPCAGVLIHPLWVITAAHCNLP 60
Query: 61 KLRVILGVTIPADSNEKHLQVIGYEKMIHHPHFSVTSIDHDIMLIKLKTEAELNDYVKLA 120
KLRVILGVTIPADSNEKHLQVIGYEKMIHHPHFSVTSIDHDIMLIKLKTEAELNDYVKLA
Sbjct: 61 KLRVILGVTIPADSNEKHLQVIGYEKMIHHPHFSVTSIDHDIMLIKLKTEAELNDYVKLA 120
Query: 121 NLPYQTISENTMCSVSTWSYNVCDIYKEPDSLQTVNISVISKPQCRDAYKTYNITENMLC 180
NLPYQTISENTMCSVSTWSYNVCDIYKEPDSLQTVNISVISKPQCRDAYKTYNITENMLC
Sbjct: 121 NLPYQTISENTMCSVSTWSYNVCDIYKEPDSLQTVNISVISKPQCRDAYKTYNITENMLC 180
Query: 181 VGIVPGRRQPCKEVSAAPAICNGMLQGILSFADGCVLRADVGIYAKIFYYIPWIENVIQN 240
VGIVPGRRQPCKEVSAAPAICNGMLQGILSFADGCVLRADVGIYAKIFYYIPWIENVIQN
Sbjct: 181 VGIVPGRRQPCKEVSAAPAICNGMLQGILSFADGCVLRADVGIYAKIFYYIPWIENVIQN 240
Query: 241 N 241
N
Sbjct: 241 N 241
>gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]
Length = 247
Score = 152 bits (385), Expect = 2e-37
Identities = 84/248 (33%), Positives = 130/248 (52%), Gaps = 9/248 (3%)
Query: 1 MKFILLWALLNLTVALAFNPDYTV-------SSTPPYLVYLKSDYLPCAGVLIHPLWVIT 53
M +L+ + +A F+ D + ++ PY V L S Y C G LI+ WV++
Sbjct: 1 MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVS 60
Query: 54 AAHCNLPKLRVILGVTIPADSNEKHLQVIGYEKMIHHPHFSVTSIDHDIMLIKLKTEAEL 113
A HC +++V LG + E + Q I K+I HP + ++++DIMLIKL + A +
Sbjct: 61 AGHCYKSRIQVRLGEH-NIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVI 119
Query: 114 NDYVKLANLPYQTISENTMCSVSTWSYNVCDIYKEPDSLQTVNISVISKPQCRDAYKTYN 173
N V +LP + T C +S W PD LQ ++ V+S+ +C +Y
Sbjct: 120 NARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPG-K 178
Query: 174 ITENMLCVGIVPGRRQPCKEVSAAPAICNGMLQGILSFADGCVLRADVGIYAKIFYYIPW 233
IT NM CVG + G + C+ S P +CNG LQG++S+ DGC + G+Y K++ Y+ W
Sbjct: 179 ITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKW 238
Query: 234 IENVIQNN 241
I+N I N
Sbjct: 239 IKNTIAAN 246
>gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens]
Length = 247
Score = 146 bits (368), Expect = 2e-35
Identities = 86/252 (34%), Positives = 132/252 (52%), Gaps = 17/252 (6%)
Query: 1 MKFILLWALLNLTVALAFNPD------YTVSSTP-PYLVYLKSDYLPCAGVLIHPLWVIT 53
M L+ A + VA+ F+ D YT PY V L S C G LI WV++
Sbjct: 1 MNPFLILAFVGAAVAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHFCGGSLISEQWVVS 60
Query: 54 AAHCNLPKLRVILGVTIPADSNEKHL----QVIGYEKMIHHPHFSVTSIDHDIMLIKLKT 109
AAHC +++V LG + N K L Q I K+I HP ++ ++D+DIMLIKL +
Sbjct: 61 AAHCYKTRIQVRLG-----EHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSS 115
Query: 110 EAELNDYVKLANLPYQTISENTMCSVSTWSYNVCDIYKEPDSLQTVNISVISKPQCRDAY 169
A +N V +LP + T C +S W + PD L+ ++ V+++ +C+ +Y
Sbjct: 116 PAVINARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASY 175
Query: 170 KTYNITENMLCVGIVPGRRQPCKEVSAAPAICNGMLQGILSFADGCVLRADVGIYAKIFY 229
IT +M CVG + G + C+ S P +CNG LQG++S+ GC + G+Y K++
Sbjct: 176 PG-KITNSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVYN 234
Query: 230 YIPWIENVIQNN 241
Y+ WI++ I N
Sbjct: 235 YVDWIKDTIAAN 246
>gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]
Length = 304
Score = 144 bits (364), Expect = 5e-35
Identities = 84/240 (35%), Positives = 128/240 (53%), Gaps = 17/240 (7%)
Query: 13 TVALAFNPD------YTVSSTP-PYLVYLKSDYLPCAGVLIHPLWVITAAHCNLPKLRVI 65
TVA+ F+ D YT PY V L S C G LI WV++AAHC +++V
Sbjct: 70 TVAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHFCGGSLISEQWVVSAAHCYKTRIQVR 129
Query: 66 LGVTIPADSNEKHL----QVIGYEKMIHHPHFSVTSIDHDIMLIKLKTEAELNDYVKLAN 121
LG + N K L Q I K+I HP ++ ++D+DIMLIKL + A +N V +
Sbjct: 130 LG-----EHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTIS 184
Query: 122 LPYQTISENTMCSVSTWSYNVCDIYKEPDSLQTVNISVISKPQCRDAYKTYNITENMLCV 181
LP + T C +S W + PD L+ ++ V+++ +C+ +Y IT +M CV
Sbjct: 185 LPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPG-KITNSMFCV 243
Query: 182 GIVPGRRQPCKEVSAAPAICNGMLQGILSFADGCVLRADVGIYAKIFYYIPWIENVIQNN 241
G + G + C+ S P +CNG LQG++S+ GC + G+Y K++ Y+ WI++ I N
Sbjct: 244 GFLEGGKDSCQRDSGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKDTIAAN 303
>gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]
Length = 247
Score = 142 bits (359), Expect = 2e-34
Identities = 82/248 (33%), Positives = 128/248 (51%), Gaps = 9/248 (3%)
Query: 1 MKFILLWALLNLTVALAFNPDYTV-------SSTPPYLVYLKSDYLPCAGVLIHPLWVIT 53
M +L+ + VA F+ D + ++ PY V L S Y C G LI WV++
Sbjct: 1 MNLLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGYHFCGGSLISEQWVVS 60
Query: 54 AAHCNLPKLRVILGVTIPADSNEKHLQVIGYEKMIHHPHFSVTSIDHDIMLIKLKTEAEL 113
A HC +++V LG + E + Q I K+I HP ++ ++D+DI+LIKL + A +
Sbjct: 61 AGHCYKSRIQVRLGEH-NIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVI 119
Query: 114 NDYVKLANLPYQTISENTMCSVSTWSYNVCDIYKEPDSLQTVNISVISKPQCRDAYKTYN 173
N V +LP + T +S W + PD LQ ++ V+S+ +C +Y
Sbjct: 120 NSRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPG-K 178
Query: 174 ITENMLCVGIVPGRRQPCKEVSAAPAICNGMLQGILSFADGCVLRADVGIYAKIFYYIPW 233
IT NM CVG + G + C+ S P + NG LQGI+S+ GC + G+Y K++ Y+ W
Sbjct: 179 ITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGYGCAQKNRPGVYTKVYNYVDW 238
Query: 234 IENVIQNN 241
I++ I N
Sbjct: 239 IKDTIAAN 246
>gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens]
Length = 261
Score = 124 bits (312), Expect = 6e-29
Identities = 74/231 (32%), Positives = 115/231 (49%), Gaps = 20/231 (8%)
Query: 26 STPPYLVYLKSDYLPCAGVLIHPLWVITAAHCNLPKLRVILG---VTIPADSNEKHLQVI 82
S P + + C GVL+HP WV+TAAHC +V LG + P D+ ++ +
Sbjct: 35 SQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPEDTGQR----V 90
Query: 83 GYEKMIHHPHFSVTSI-----------DHDIMLIKLKTEAELNDYVKLANLPYQTISENT 131
HP ++++ + HD+ML++L A++ D VK+ LP Q + T
Sbjct: 91 PVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQEPALGT 150
Query: 132 MCSVSTWSYNVCDIYKEPDSLQTVNISVISKPQCRDAYKTYNITENMLCVGIVPGRRQPC 191
C S W + + P SLQ V++ ++S C AY + +TE MLC G+ G + C
Sbjct: 151 TCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAY-SEKVTEFMLCAGLWTGGKDTC 209
Query: 192 KEVSAAPAICNGMLQGILSFA-DGCVLRADVGIYAKIFYYIPWIENVIQNN 241
S P +CNG+LQGI S+ + C L +Y K+ +Y WI++ I N
Sbjct: 210 GGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260
>gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 123 bits (309), Expect = 1e-28
Identities = 71/218 (32%), Positives = 112/218 (51%), Gaps = 9/218 (4%)
Query: 25 SSTPPYLVYLKSDYLPCAGVLIHPLWVITAAHCNLPKLRVILGV--TIPADSNEKHLQVI 82
+S P S +L C GVLIHPLWV+TAAHC P L+V LG +S+++ V+
Sbjct: 31 TSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLRQRESSQEQSSVV 90
Query: 83 GYEKMIHHPHFSVTSIDHDIMLIKLKTEAELNDYVKLANLPYQTISENTMCSVSTWSYNV 142
+ + HP + S D DIML++L A+L++ ++ L + T C + W
Sbjct: 91 ---RAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSANTTSCHILGWGKTA 147
Query: 143 CDIYKEPDSLQTVNISVISKPQCRDAYKTYNITENMLCVGIVPGRRQPCKEVSAAPAICN 202
+ PD++Q I ++S+ +C AY IT+NMLC G + C+ S P +C
Sbjct: 148 DGDF--PDTIQCAYIHLVSREECEHAYPG-QITQNMLCAGDEKYGKDSCQGDSGGPLVCG 204
Query: 203 GMLQGILSFAD-GCVLRADVGIYAKIFYYIPWIENVIQ 239
L+G++S+ + C + G+Y + Y WI+ IQ
Sbjct: 205 DHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQ 242
>gi|4506155 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 123 bits (309), Expect = 1e-28
Identities = 71/218 (32%), Positives = 112/218 (51%), Gaps = 9/218 (4%)
Query: 25 SSTPPYLVYLKSDYLPCAGVLIHPLWVITAAHCNLPKLRVILGV--TIPADSNEKHLQVI 82
+S P S +L C GVLIHPLWV+TAAHC P L+V LG +S+++ V+
Sbjct: 31 TSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLRQRESSQEQSSVV 90
Query: 83 GYEKMIHHPHFSVTSIDHDIMLIKLKTEAELNDYVKLANLPYQTISENTMCSVSTWSYNV 142
+ + HP + S D DIML++L A+L++ ++ L + T C + W
Sbjct: 91 ---RAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSANTTSCHILGWGKTA 147
Query: 143 CDIYKEPDSLQTVNISVISKPQCRDAYKTYNITENMLCVGIVPGRRQPCKEVSAAPAICN 202
+ PD++Q I ++S+ +C AY IT+NMLC G + C+ S P +C
Sbjct: 148 DGDF--PDTIQCAYIHLVSREECEHAYPG-QITQNMLCAGDEKYGKDSCQGDSGGPLVCG 204
Query: 203 GMLQGILSFAD-GCVLRADVGIYAKIFYYIPWIENVIQ 239
L+G++S+ + C + G+Y + Y WI+ IQ
Sbjct: 205 DHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQ 242
>gi|21327705 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 122 bits (307), Expect = 2e-28
Identities = 69/217 (31%), Positives = 106/217 (48%), Gaps = 5/217 (2%)
Query: 26 STPPYLVYLKSDYLPCAGVLIHPLWVITAAHCNLPKLRVILGVTIPADSNEKHLQVIGYE 85
S P + L + L C GVL++ WV+TAAHC + + V LG D + Q I
Sbjct: 40 SHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGD---RRAQRIKAS 96
Query: 86 KMIHHPHFSVTSIDHDIMLIKLKTEAELNDYVKLANLPYQTISENTMCSVSTWSYNVCDI 145
K HP +S + +D+ML+KL ++A L+ VK LP + T C+VS W
Sbjct: 97 KSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPD 156
Query: 146 YKEPDSLQTVNISVISKPQCRDAYKTYNITENMLCVGIVPGRRQPCKEVSAAPAICNGML 205
P L V++ +IS C YK + +MLC GI ++ C S P +C G L
Sbjct: 157 VTFPSDLMCVDVKLISPQDCTKVYKDL-LENSMLCAGIPDSKKNACNGDSGGPLVCRGTL 215
Query: 206 QGILSFAD-GCVLRADVGIYAKIFYYIPWIENVIQNN 241
QG++S+ C D G+Y ++ + WI + ++ +
Sbjct: 216 QGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252
>gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 122 bits (307), Expect = 2e-28
Identities = 69/217 (31%), Positives = 106/217 (48%), Gaps = 5/217 (2%)
Query: 26 STPPYLVYLKSDYLPCAGVLIHPLWVITAAHCNLPKLRVILGVTIPADSNEKHLQVIGYE 85
S P + L + L C GVL++ WV+TAAHC + + V LG D + Q I
Sbjct: 40 SHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGD---RRAQRIKAS 96
Query: 86 KMIHHPHFSVTSIDHDIMLIKLKTEAELNDYVKLANLPYQTISENTMCSVSTWSYNVCDI 145
K HP +S + +D+ML+KL ++A L+ VK LP + T C+VS W
Sbjct: 97 KSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPD 156
Query: 146 YKEPDSLQTVNISVISKPQCRDAYKTYNITENMLCVGIVPGRRQPCKEVSAAPAICNGML 205
P L V++ +IS C YK + +MLC GI ++ C S P +C G L
Sbjct: 157 VTFPSDLMCVDVKLISPQDCTKVYKDL-LENSMLCAGIPDSKKNACNGDSGGPLVCRGTL 215
Query: 206 QGILSFAD-GCVLRADVGIYAKIFYYIPWIENVIQNN 241
QG++S+ C D G+Y ++ + WI + ++ +
Sbjct: 216 QGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252
>gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 122 bits (305), Expect = 4e-28
Identities = 75/209 (35%), Positives = 101/209 (48%), Gaps = 3/209 (1%)
Query: 34 LKSDYLPCAGVLIHPLWVITAAHCNLPKLRVILGVTIPADSNEKHLQVIGYEKMIHHPHF 93
L+ + L C VL+HP W++TAAHC RV LG + E Q+ K I HP +
Sbjct: 86 LRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGY 145
Query: 94 SVTSIDHDIMLIKLKTEAELNDYVKLANLPYQTISENTMCSVSTWSYNVCDIYKEPDSLQ 153
S +D+MLIKL V+ N+ S T C VS W P LQ
Sbjct: 146 SHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQ 205
Query: 154 TVNISVISKPQCRDAYKTYNITENMLCVGIVPGRRQPCKEVSAAPAICNGMLQGILSFAD 213
+NISV+S+ +C DAY I + M C G G R C+ S P +CNG LQG++S+ D
Sbjct: 206 CLNISVLSQKRCEDAYPR-QIDDTMFCAGDKAG-RDSCQGDSGGPVVCNGSLQGLVSWGD 263
Query: 214 -GCVLRADVGIYAKIFYYIPWIENVIQNN 241
C G+Y + + WI+ IQ N
Sbjct: 264 YPCARPNRPGVYTNLCKFTKWIQETIQAN 292
>gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 122 bits (305), Expect = 4e-28
Identities = 75/209 (35%), Positives = 101/209 (48%), Gaps = 3/209 (1%)
Query: 34 LKSDYLPCAGVLIHPLWVITAAHCNLPKLRVILGVTIPADSNEKHLQVIGYEKMIHHPHF 93
L+ + L C VL+HP W++TAAHC RV LG + E Q+ K I HP +
Sbjct: 86 LRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGY 145
Query: 94 SVTSIDHDIMLIKLKTEAELNDYVKLANLPYQTISENTMCSVSTWSYNVCDIYKEPDSLQ 153
S +D+MLIKL V+ N+ S T C VS W P LQ
Sbjct: 146 SHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQ 205
Query: 154 TVNISVISKPQCRDAYKTYNITENMLCVGIVPGRRQPCKEVSAAPAICNGMLQGILSFAD 213
+NISV+S+ +C DAY I + M C G G R C+ S P +CNG LQG++S+ D
Sbjct: 206 CLNISVLSQKRCEDAYPR-QIDDTMFCAGDKAG-RDSCQGDSGGPVVCNGSLQGLVSWGD 263
Query: 214 -GCVLRADVGIYAKIFYYIPWIENVIQNN 241
C G+Y + + WI+ IQ N
Sbjct: 264 YPCARPNRPGVYTNLCKFTKWIQETIQAN 292
>gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 122 bits (305), Expect = 4e-28
Identities = 75/209 (35%), Positives = 101/209 (48%), Gaps = 3/209 (1%)
Query: 34 LKSDYLPCAGVLIHPLWVITAAHCNLPKLRVILGVTIPADSNEKHLQVIGYEKMIHHPHF 93
L+ + L C VL+HP W++TAAHC RV LG + E Q+ K I HP +
Sbjct: 86 LRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGY 145
Query: 94 SVTSIDHDIMLIKLKTEAELNDYVKLANLPYQTISENTMCSVSTWSYNVCDIYKEPDSLQ 153
S +D+MLIKL V+ N+ S T C VS W P LQ
Sbjct: 146 SHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQ 205
Query: 154 TVNISVISKPQCRDAYKTYNITENMLCVGIVPGRRQPCKEVSAAPAICNGMLQGILSFAD 213
+NISV+S+ +C DAY I + M C G G R C+ S P +CNG LQG++S+ D
Sbjct: 206 CLNISVLSQKRCEDAYPR-QIDDTMFCAGDKAG-RDSCQGDSGGPVVCNGSLQGLVSWGD 263
Query: 214 -GCVLRADVGIYAKIFYYIPWIENVIQNN 241
C G+Y + + WI+ IQ N
Sbjct: 264 YPCARPNRPGVYTNLCKFTKWIQETIQAN 292
>gi|4502173 prostate specific antigen isoform 1 preproprotein [Homo
sapiens]
Length = 261
Score = 121 bits (304), Expect = 5e-28
Identities = 74/216 (34%), Positives = 108/216 (50%), Gaps = 20/216 (9%)
Query: 41 CAGVLIHPLWVITAAHCNLPKLRVILG---VTIPADSNEKHLQVIGYEKMIHHPHFSVTS 97
C GVL+HP WV+TAAHC K ++LG + P D+ QV HP + ++
Sbjct: 50 CGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPEDTG----QVFQVSHSFPHPLYDMSL 105
Query: 98 I-----------DHDIMLIKLKTEAELNDYVKLANLPYQTISENTMCSVSTWSYNVCDIY 146
+ HD+ML++L AEL D VK+ +LP Q + T C S W + +
Sbjct: 106 LKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEF 165
Query: 147 KEPDSLQTVNISVISKPQCRDAYKTYNITENMLCVGIVPGRRQPCKEVSAAPAICNGMLQ 206
P LQ V++ VIS C + +T+ MLC G G + C S P +CNG+LQ
Sbjct: 166 LTPKKLQCVDLHVISNDVCAQVH-PQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQ 224
Query: 207 GILSF-ADGCVLRADVGIYAKIFYYIPWIENVIQNN 241
GI S+ ++ C L +Y K+ +Y WI++ I N
Sbjct: 225 GITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260
>gi|11496281 kallikrein 13 precursor [Homo sapiens]
Length = 277
Score = 120 bits (302), Expect = 8e-28
Identities = 77/222 (34%), Positives = 111/222 (50%), Gaps = 12/222 (5%)
Query: 26 STPPYLVYLKSDYLPCAGVLIHPLWVITAAHCNLPKLRVILG--VTIPADSNEKHLQVIG 83
S P L L C GVL+HP WV+TAAHC L+V LG ++ E+ +V+
Sbjct: 46 SQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAGEQVREVV- 104
Query: 84 YEKMIHHPHF--SVTSI--DHDIMLIKLKTEAELNDYVKLANLPYQT-ISENTMCSVSTW 138
I HP + S T + DHDIML++L++ +L Y++ L + ++ T C VS W
Sbjct: 105 --HSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTCRVSGW 162
Query: 139 SYNVCDIYKEPDSLQTVNISVISKPQCRDAYKTYNITENMLCVGIVPGRRQPCKEVSAAP 198
P +LQ NI + S +CR Y IT+NMLC G G + C+ S P
Sbjct: 163 GTTTSPQVNYPKTLQCANIQLRSDEECRQVYPG-KITDNMLCAGTKEGGKDSCEGDSGGP 221
Query: 199 AICNGMLQGILSFAD-GCVLRADVGIYAKIFYYIPWIENVIQ 239
+CN L GI+S+ D C G+Y ++ Y+ WI I+
Sbjct: 222 LVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETIR 263
>gi|91823048 kallikrein 14 preproprotein [Homo sapiens]
Length = 267
Score = 118 bits (296), Expect = 4e-27
Identities = 68/201 (33%), Positives = 103/201 (51%), Gaps = 3/201 (1%)
Query: 41 CAGVLIHPLWVITAAHCNLPKLRVILGVTIPADSNEKHLQVIGYEKMIHHPHFSVTSIDH 100
C G L+ WVITAAHC P L+V LG E QV+ + + HP+++ + D+
Sbjct: 68 CGGALLSGQWVITAAHCGRPILQVALGKH-NLRRWEATQQVLRVVRQVTHPNYNSRTHDN 126
Query: 101 DIMLIKLKTEAELNDYVKLANLPYQTISENTMCSVSTWSYNVCDIYKEPDSLQTVNISVI 160
D+ML++L+ A + V+ + S T C VS W I + P SLQ VNI++
Sbjct: 127 DLMLLQLQQPARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINIS 186
Query: 161 SKPQCRDAYKTYNITENMLCVGIVPGRRQPCKEVSAAPAICNGMLQGILSFA-DGCVLRA 219
C+ AY IT M+C G+ G + C+ S P +C G LQG++S+ + C L
Sbjct: 187 PDEVCQKAYPR-TITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPG 245
Query: 220 DVGIYAKIFYYIPWIENVIQN 240
G+Y + Y WIE +++
Sbjct: 246 YPGVYTNLCKYRSWIEETMRD 266
>gi|56606135 hypothetical protein LOC136242 [Homo sapiens]
Length = 235
Score = 118 bits (295), Expect = 5e-27
Identities = 74/212 (34%), Positives = 111/212 (52%), Gaps = 5/212 (2%)
Query: 29 PYLVYLKSDYLPCAGVLIHPLWVITAAHCNLPKLRVILGVTIPADSNEKHLQVIGYEKMI 88
PYLVYLKS + PC GVLI P WV+ AHC LP L+V+LG + + Q I +++
Sbjct: 28 PYLVYLKSHFNPCVGVLIKPSWVLAPAHCYLPNLKVMLG-NFKSRVRDGTEQTINPIQIV 86
Query: 89 HHPHFSVTSIDHDIMLIKLKTEAELNDYVKLANLPYQTISENTMCSVSTWSYNVCDIYKE 148
+ ++S ++ D+MLIKL A LN V+ L + T+C +S ++ + +
Sbjct: 87 RYWNYSHSAPQDDLMLIKLAKPAMLNPKVQPLPLATTNVRPGTVCLLSGLDWSQENSGRH 146
Query: 149 PDSLQTVNISVISKPQCRDAYKTYNITENMLCVGIVPGRRQPCKEVSAAPAICNGMLQGI 208
PD Q + V+S +C+ + + N LCV V + EV+ A IC LQGI
Sbjct: 147 PDLRQNLEAPVMSDRECQKTEQGKS-HRNSLCVKFVKVFSRIFGEVAVATVICKDKLQGI 205
Query: 209 LSFADGCVLRADVGIYAKIFYYIPWIENVIQN 240
G + DVGIY ++ Y+ WIEN ++
Sbjct: 206 ---EVGHFMGGDVGIYTNVYKYVSWIENTAKD 234
>gi|22208987 kallikrein 12 isoform 2 [Homo sapiens]
Length = 248
Score = 117 bits (293), Expect = 9e-27
Identities = 83/256 (32%), Positives = 121/256 (47%), Gaps = 25/256 (9%)
Query: 1 MKFILLWALLNLTVALA---FNPDYTVSSTPPYLVYL-KSDYLPCAGVLIHPLWVITAAH 56
+ LL +L L+ A FN ++ P+ V L + L C GVLI WV+TAAH
Sbjct: 3 LSIFLLLCVLGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAH 62
Query: 57 CNLPKLRVILGVTIPADSNEKHLQVIGYEKMIHHPHFSV---------TSIDHDIMLIKL 107
C+ + V LG E L + + + I H FSV TS +HD+ L++L
Sbjct: 63 CSGSRYWVRLG--------EHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRL 114
Query: 108 KTEAELNDYVKLANLPYQTISENTMCSVSTWSYNVCDIYKEPDSLQTVNISVISKPQCRD 167
+ + V+ LP + T C VS W PD LQ +N+S++S C
Sbjct: 115 RLPVRVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHG 174
Query: 168 AYKTYNITENMLCVGIVPGRRQPCKEVSAAPAICNGMLQGILSFAD--GCVLRADVGIYA 225
Y IT NM+C G VPG + C+ S P +C G+LQG++S+ C G+Y
Sbjct: 175 VYPG-RITSNMVCAGGVPG-QDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYT 232
Query: 226 KIFYYIPWIENVIQNN 241
I Y+ WI +++NN
Sbjct: 233 YICKYVDWIRMIMRNN 248
>gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 116 bits (290), Expect = 2e-26
Identities = 70/221 (31%), Positives = 108/221 (48%), Gaps = 7/221 (3%)
Query: 26 STPPYLVYLKSDYLPCAGVLIHPLWVITAAHCNLPKLRVILGVTIPADSNEKHLQVIGYE 85
S P + L C LI P W++TAAHC P+ V LG E Q
Sbjct: 32 SQPWQAALFEKTRLLCGATLIAPRWLLTAAHCLKPRYIVHLGQH-NLQKEEGCEQTRTAT 90
Query: 86 KMIHHPHF--SVTSIDH--DIMLIKLKTEAELNDYVKLANLPYQTISENTMCSVSTWSYN 141
+ HP F S+ + DH DIML+K+ + + V+ L + ++ T C +S W
Sbjct: 91 ESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGST 150
Query: 142 VCDIYKEPDSLQTVNISVISKPQCRDAYKTYNITENMLCVGIVPGRRQPCKEVSAAPAIC 201
+ P +L+ NI++I +C +AY NIT+ M+C + G + C+ S P +C
Sbjct: 151 SSPQLRLPHTLRCANITIIEHQKCENAYPG-NITDTMVCASVQEGGKDSCQGDSGGPLVC 209
Query: 202 NGMLQGILSFA-DGCVLRADVGIYAKIFYYIPWIENVIQNN 241
N LQGI+S+ D C + G+Y K+ Y+ WI+ ++NN
Sbjct: 210 NQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETMKNN 250
>gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens]
Length = 282
Score = 116 bits (290), Expect = 2e-26
Identities = 70/221 (31%), Positives = 108/221 (48%), Gaps = 7/221 (3%)
Query: 26 STPPYLVYLKSDYLPCAGVLIHPLWVITAAHCNLPKLRVILGVTIPADSNEKHLQVIGYE 85
S P + L C LI P W++TAAHC P+ V LG E Q
Sbjct: 64 SQPWQAALFEKTRLLCGATLIAPRWLLTAAHCLKPRYIVHLGQH-NLQKEEGCEQTRTAT 122
Query: 86 KMIHHPHF--SVTSIDH--DIMLIKLKTEAELNDYVKLANLPYQTISENTMCSVSTWSYN 141
+ HP F S+ + DH DIML+K+ + + V+ L + ++ T C +S W
Sbjct: 123 ESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGST 182
Query: 142 VCDIYKEPDSLQTVNISVISKPQCRDAYKTYNITENMLCVGIVPGRRQPCKEVSAAPAIC 201
+ P +L+ NI++I +C +AY NIT+ M+C + G + C+ S P +C
Sbjct: 183 SSPQLRLPHTLRCANITIIEHQKCENAYPG-NITDTMVCASVQEGGKDSCQGDSGGPLVC 241
Query: 202 NGMLQGILSFA-DGCVLRADVGIYAKIFYYIPWIENVIQNN 241
N LQGI+S+ D C + G+Y K+ Y+ WI+ ++NN
Sbjct: 242 NQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETMKNN 282
>gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 116 bits (290), Expect = 2e-26
Identities = 70/221 (31%), Positives = 108/221 (48%), Gaps = 7/221 (3%)
Query: 26 STPPYLVYLKSDYLPCAGVLIHPLWVITAAHCNLPKLRVILGVTIPADSNEKHLQVIGYE 85
S P + L C LI P W++TAAHC P+ V LG E Q
Sbjct: 32 SQPWQAALFEKTRLLCGATLIAPRWLLTAAHCLKPRYIVHLGQH-NLQKEEGCEQTRTAT 90
Query: 86 KMIHHPHF--SVTSIDH--DIMLIKLKTEAELNDYVKLANLPYQTISENTMCSVSTWSYN 141
+ HP F S+ + DH DIML+K+ + + V+ L + ++ T C +S W
Sbjct: 91 ESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGST 150
Query: 142 VCDIYKEPDSLQTVNISVISKPQCRDAYKTYNITENMLCVGIVPGRRQPCKEVSAAPAIC 201
+ P +L+ NI++I +C +AY NIT+ M+C + G + C+ S P +C
Sbjct: 151 SSPQLRLPHTLRCANITIIEHQKCENAYPG-NITDTMVCASVQEGGKDSCQGDSGGPLVC 209
Query: 202 NGMLQGILSFA-DGCVLRADVGIYAKIFYYIPWIENVIQNN 241
N LQGI+S+ D C + G+Y K+ Y+ WI+ ++NN
Sbjct: 210 NQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETMKNN 250
>gi|21464127 kallikrein 8 isoform 2 [Homo sapiens]
Length = 305
Score = 112 bits (280), Expect = 3e-25
Identities = 71/219 (32%), Positives = 106/219 (48%), Gaps = 11/219 (5%)
Query: 26 STPPYLVYLKSDYLPCAGVLIHPLWVITAAHCNLPKLRVILG--VTIPADSNEKHLQVIG 83
S P + L C GVL+ WV+TAAHC PK V LG D E+ + V+
Sbjct: 88 SQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQNKDGPEQEIPVV- 146
Query: 84 YEKMIHHPHFSVTSID---HDIMLIKLKTEAELNDYVKLANLPYQTISENTMCSVSTWSY 140
+ I HP ++ + ++ HD+ML++L+ +A L VK +L C+VS W
Sbjct: 147 --QSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPGQKCTVSGWGT 204
Query: 141 NVCDIYKEPDSLQTVNISVISKPQCRDAYKTYNITENMLCVGIVPGRRQPCKEVSAAPAI 200
PD+L + + + +C DAY IT+ M+C G G C+ S P +
Sbjct: 205 VTSPRENFPDTLNCAEVKIFPQKKCEDAYPG-QITDGMVCAGSSKG-ADTCQGDSGGPLV 262
Query: 201 CNGMLQGILSF-ADGCVLRADVGIYAKIFYYIPWIENVI 238
C+G LQGI S+ +D C G+Y I Y+ WI+ +I
Sbjct: 263 CDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 301
>gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens]
Length = 260
Score = 112 bits (280), Expect = 3e-25
Identities = 71/219 (32%), Positives = 106/219 (48%), Gaps = 11/219 (5%)
Query: 26 STPPYLVYLKSDYLPCAGVLIHPLWVITAAHCNLPKLRVILG--VTIPADSNEKHLQVIG 83
S P + L C GVL+ WV+TAAHC PK V LG D E+ + V+
Sbjct: 43 SQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQNKDGPEQEIPVV- 101
Query: 84 YEKMIHHPHFSVTSID---HDIMLIKLKTEAELNDYVKLANLPYQTISENTMCSVSTWSY 140
+ I HP ++ + ++ HD+ML++L+ +A L VK +L C+VS W
Sbjct: 102 --QSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPGQKCTVSGWGT 159
Query: 141 NVCDIYKEPDSLQTVNISVISKPQCRDAYKTYNITENMLCVGIVPGRRQPCKEVSAAPAI 200
PD+L + + + +C DAY IT+ M+C G G C+ S P +
Sbjct: 160 VTSPRENFPDTLNCAEVKIFPQKKCEDAYPG-QITDGMVCAGSSKG-ADTCQGDSGGPLV 217
Query: 201 CNGMLQGILSF-ADGCVLRADVGIYAKIFYYIPWIENVI 238
C+G LQGI S+ +D C G+Y I Y+ WI+ +I
Sbjct: 218 CDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 256
>gi|71834855 prostate specific antigen isoform 4 preproprotein [Homo
sapiens]
Length = 218
Score = 111 bits (277), Expect = 6e-25
Identities = 67/202 (33%), Positives = 95/202 (47%), Gaps = 35/202 (17%)
Query: 41 CAGVLIHPLWVITAAHCNLPKLRVILGVTIPADSNEKHLQVIGYEKMIHHPHFSVTSIDH 100
C GVL+HP WV+TAAHC + P D + H
Sbjct: 50 CGGVLVHPQWVLTAAHC----------IRKPGDDS-----------------------SH 76
Query: 101 DIMLIKLKTEAELNDYVKLANLPYQTISENTMCSVSTWSYNVCDIYKEPDSLQTVNISVI 160
D+ML++L AEL D VK+ +LP Q + T C S W + + P LQ V++ VI
Sbjct: 77 DLMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVI 136
Query: 161 SKPQCRDAYKTYNITENMLCVGIVPGRRQPCKEVSAAPAICNGMLQGILSF-ADGCVLRA 219
S C + +T+ MLC G G + C S P +CNG+LQGI S+ ++ C L
Sbjct: 137 SNDVCAQVH-PQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPE 195
Query: 220 DVGIYAKIFYYIPWIENVIQNN 241
+Y K+ +Y WI++ I N
Sbjct: 196 RPSLYTKVVHYRKWIKDTIVAN 217
>gi|4504235 granzyme K precursor [Homo sapiens]
Length = 264
Score = 108 bits (271), Expect = 3e-24
Identities = 69/207 (33%), Positives = 106/207 (51%), Gaps = 13/207 (6%)
Query: 41 CAGVLIHPLWVITAAHCNLPKLR-----VILGVTIPADSNEKHLQVIGYEKMIHHPHFSV 95
C GVLI P WV+TAAHC + V+LG NE Q + +K I +
Sbjct: 52 CGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAH-SLSKNEASKQTLEIKKFIPFSRVTS 110
Query: 96 TSIDHDIMLIKLKTEAELNDYVKLANLPYQT-ISENTMCSVSTWSYNVCDIYKEPDSLQT 154
+DIML+KL+T A+LN +VK+ ++ +T + T C V+ W D + D+L+
Sbjct: 111 DPQSNDIMLVKLQTAAKLNKHVKMLHIRSKTSLRSGTKCKVTGWGATDPDSLRPSDTLRE 170
Query: 155 VNISVISKPQCRDAYKTYN----ITENMLCVGIVPGRRQPCKEVSAAPAICNGMLQGILS 210
V ++V+S+ C ++ YN IT++M+C G G++ CK S P IC G+ I+S
Sbjct: 171 VTVTVLSRKLC-NSQSYYNGDPFITKDMVCAGDAKGQKDSCKGDSGGPLICKGVFHAIVS 229
Query: 211 FADGCVLRADVGIYAKIF-YYIPWIEN 236
C + GIY + Y WI++
Sbjct: 230 GGHECGVATKPGIYTLLTKKYQTWIKS 256
>gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprotein
[Homo sapiens]
Length = 256
Score = 108 bits (270), Expect = 4e-24
Identities = 80/259 (30%), Positives = 117/259 (45%), Gaps = 26/259 (10%)
Query: 6 LWALLNLTVALA----------FNPDYTVSSTPPYLVYL-KSDYLPCAGVLIHPLWVITA 54
+W LL L+ LA D + P+ V L + C LI P WV++A
Sbjct: 1 MWLLLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSA 60
Query: 55 AHCNLPKLRVILGV-TIPADSNEKHLQVIGYEKMIHHPHFSVTSIDHDIMLIKLKTEAEL 113
AHC +RV LG + + L+ ++I HP + S +DIML++L A L
Sbjct: 61 AHCQSRFMRVRLGEHNLRKRDGPEQLRTTS--RVIPHPRYEARSHRNDIMLLRLVQPARL 118
Query: 114 NDYVKLANLPYQTISENTMCSVSTW---SYNVCDI-------YKEPDSLQTVNISVISKP 163
N V+ A LP + C VS W S+N PD+L NIS+IS
Sbjct: 119 NPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDT 178
Query: 164 QCRDAYKTYNITENMLCVGIVPGRRQPCKEVSAAPAICNGMLQGILSFAD-GCVLRADVG 222
C +Y +T M+C G + C+ S P +C G+LQGI+S+ D C G
Sbjct: 179 SCDKSYPG-RLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPG 237
Query: 223 IYAKIFYYIPWIENVIQNN 241
+Y K+ +Y+ WI ++ N
Sbjct: 238 VYTKVCHYLEWIRETMKRN 256
>gi|4504875 kallikrein 1 preproprotein [Homo sapiens]
Length = 262
Score = 108 bits (269), Expect = 5e-24
Identities = 63/214 (29%), Positives = 107/214 (50%), Gaps = 15/214 (7%)
Query: 41 CAGVLIHPLWVITAAHCNLPKLRVILGVTIPADSNEKHLQVIGYEKMIHHPHFSVTSID- 99
C G+L+H WV+TAAHC ++ LG D +E Q + + HP F+++ ++
Sbjct: 50 CGGILVHRQWVLTAAHCISDNYQLWLGRHNLFD-DENTAQFVHVSESFPHPGFNMSLLEN 108
Query: 100 ----------HDIMLIKLKTEAE-LNDYVKLANLPYQTISENTMCSVSTWSYNVCDIYKE 148
HD+ML++L A+ + D VK+ LP + + C S W + +
Sbjct: 109 HTRQADEDYSHDLMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSF 168
Query: 149 PDSLQTVNISVISKPQCRDAYKTYNITENMLCVGIVPGRRQPCKEVSAAPAICNGMLQGI 208
PD LQ V++ ++ +C+ A+ +T+ MLCVG + G + C S P +C+G+LQG+
Sbjct: 169 PDDLQCVDLKILPNDECKKAH-VQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGV 227
Query: 209 LSFA-DGCVLRADVGIYAKIFYYIPWIENVIQNN 241
S+ C + ++ Y+ WIE+ I N
Sbjct: 228 TSWGYVPCGTPNKPSVAVRVLSYVKWIEDTIAEN 261
>gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo
sapiens]
Length = 254
Score = 108 bits (269), Expect = 5e-24
Identities = 66/220 (30%), Positives = 103/220 (46%), Gaps = 4/220 (1%)
Query: 21 DYTVSSTPPYLVYLKSDYLPCAGVLIHPLWVITAAHCNLPKLRVILGVTIPADSNEKHLQ 80
D + S P + + L C+GVL+HP WV++AAHC + LG+ E Q
Sbjct: 36 DCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQEPGSQ 95
Query: 81 VIGYEKMIHHPHFSVTSIDHDIMLIKLKTEAELNDYVKLANLPYQTISENTMCSVSTWSY 140
++ + HP ++ + +D+MLIKL +D ++ ++ Q + C VS W
Sbjct: 96 MVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLVSGW-- 153
Query: 141 NVCDIYKEPDSLQTVNISVISKPQCRDAYKTYNITENMLCVGIVPGRRQPCKEVSAAPAI 200
+ + P LQ VN+SV+S+ C Y +M C G ++ C S P I
Sbjct: 154 GLLANGRMPTVLQCVNVSVVSEEVCSKLYDPL-YHPSMFCAGGGHDQKDSCNGDSGGPLI 212
Query: 201 CNGMLQGILSFADG-CVLRADVGIYAKIFYYIPWIENVIQ 239
CNG LQG++SF C G+Y + + WIE +Q
Sbjct: 213 CNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252
>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
Length = 638
Score = 108 bits (269), Expect = 5e-24
Identities = 71/212 (33%), Positives = 110/212 (51%), Gaps = 13/212 (6%)
Query: 41 CAGVLIHPLWVITAAHC--NLPKL---RVILGVTIPADSNEKHLQVIGYEKMIHHPHFSV 95
C G LI WV+TAAHC LP R+ G+ +D K +++I H ++ V
Sbjct: 419 CGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDIT-KDTPFSQIKEIIIHQNYKV 477
Query: 96 TSIDHDIMLIKLKTEAELNDYVKLANLPYQ--TISENTMCSVSTWSYNVCDIYKEPDSLQ 153
+ +HDI LIKL+ ++ K LP + T + T C V+ W ++ + + + LQ
Sbjct: 478 SEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSK-EKGEIQNILQ 536
Query: 154 TVNISVISKPQCRDAYKTYNITENMLCVGIVPGRRQPCKEVSAAPAIC--NGM--LQGIL 209
VNI +++ +C+ Y+ Y IT+ M+C G G + CK S P +C NGM L GI
Sbjct: 537 KVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGIT 596
Query: 210 SFADGCVLRADVGIYAKIFYYIPWIENVIQNN 241
S+ +GC R G+Y K+ Y+ WI Q++
Sbjct: 597 SWGEGCARREQPGVYTKVAEYMDWILEKTQSS 628
>gi|29366812 kallikrein-related peptidase 9 [Homo sapiens]
Length = 250
Score = 108 bits (269), Expect = 5e-24
Identities = 70/212 (33%), Positives = 104/212 (49%), Gaps = 21/212 (9%)
Query: 41 CAGVLIHPLWVITAAHCNLPKLRVILGVTIPADSNEKHL-------QVIGYEKMIHHPHF 93
C LI W++TAAHC P L V LG E HL Q+ HP F
Sbjct: 48 CGATLISDRWLLTAAHCRKPYLWVRLG--------EHHLWKWEGPEQLFRVTDFFPHPGF 99
Query: 94 S--VTSIDH--DIMLIKLKTEAELNDYVKLANLPYQTISENTMCSVSTWSYNVCDIYKEP 149
+ +++ DH DIMLI+L +A L+ V+ NL +S C +S W P
Sbjct: 100 NKDLSANDHNDDIMLIRLPRQARLSPAVQPLNLSQTCVSPGMQCLISGWGAVSSPKALFP 159
Query: 150 DSLQTVNISVISKPQCRDAYKTYNITENMLCVGIVPGRRQPCKEVSAAPAICNGMLQGIL 209
+LQ NIS++ C AY + I+++MLC G+ G R C+ S P +CNG L G++
Sbjct: 160 VTLQCANISILENKLCHWAYPGH-ISDSMLCAGLWEGGRGSCQGDSGGPLVCNGTLAGVV 218
Query: 210 S-FADGCVLRADVGIYAKIFYYIPWIENVIQN 240
S A+ C +Y + +Y+ WI+ +++N
Sbjct: 219 SGGAEPCSRPRRPAVYTSVCHYLDWIQEIMEN 250
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.138 0.433
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,141,968
Number of Sequences: 37866
Number of extensions: 367006
Number of successful extensions: 1201
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 150
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 710
Number of HSP's gapped (non-prelim): 189
length of query: 241
length of database: 18,247,518
effective HSP length: 99
effective length of query: 142
effective length of database: 14,498,784
effective search space: 2058827328
effective search space used: 2058827328
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.