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Search of human proteins with 47778940
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|47778940 C-type lectin, superfamily member 13 [Homo sapiens]
(589 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|47778940 C-type lectin, superfamily member 13 [Homo sapiens] 1159 0.0
gi|90991712 CD207 antigen, langerin [Homo sapiens] 148 2e-35
gi|53832016 C-type lectin, superfamily member 14 isoform 2 [Homo... 84 4e-16
gi|18426877 asialoglycoprotein receptor 2 isoform c [Homo sapiens] 81 3e-15
gi|18426875 asialoglycoprotein receptor 2 isoform b [Homo sapiens] 81 3e-15
gi|18426873 asialoglycoprotein receptor 2 isoform a [Homo sapiens] 81 3e-15
gi|4502253 asialoglycoprotein receptor 2 isoform a [Homo sapiens] 81 3e-15
gi|223278342 C-type lectin domain family 4, member M isoform 11 ... 80 5e-15
gi|223278347 C-type lectin domain family 4, member M isoform 9 [... 78 2e-14
gi|223278339 C-type lectin domain family 4, member M isoform 7 [... 76 8e-14
gi|33667103 C-type lectin, superfamily member 14 isoform 1 [Homo... 76 8e-14
gi|223029517 CD209 molecule isoform 8 [Homo sapiens] 75 1e-13
gi|223029384 CD209 molecule isoform 7 [Homo sapiens] 75 2e-13
gi|223029380 CD209 molecule isoform 5 [Homo sapiens] 75 2e-13
gi|223029386 CD209 molecule isoform 3 [Homo sapiens] 75 2e-13
gi|223029382 CD209 molecule isoform 6 [Homo sapiens] 75 2e-13
gi|10863957 CD209 molecule isoform 1 [Homo sapiens] 75 2e-13
gi|223278337 C-type lectin domain family 4, member M isoform 12 ... 74 3e-13
gi|223278335 C-type lectin domain family 4, member M isoform 2 [... 74 3e-13
gi|223278350 C-type lectin domain family 4, member M isoform 8 [... 74 3e-13
gi|42542390 C-type lectin domain family 4, member M isoform 1 [H... 74 3e-13
gi|38372935 brevican isoform 1 [Homo sapiens] 72 1e-12
gi|223029388 CD209 molecule isoform 4 [Homo sapiens] 72 2e-12
gi|31542313 C-type lectin domain family 4, member D [Homo sapiens] 69 9e-12
gi|55770834 centromere protein F [Homo sapiens] 69 2e-11
gi|4502251 asialoglycoprotein receptor 1 [Homo sapiens] 68 2e-11
gi|21735548 centrosomal protein 2 [Homo sapiens] 68 3e-11
gi|55742774 dectin-2 [Homo sapiens] 67 5e-11
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 66 1e-10
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 66 1e-10
>gi|47778940 C-type lectin, superfamily member 13 [Homo sapiens]
Length = 589
Score = 1159 bits (2998), Expect = 0.0
Identities = 589/589 (100%), Positives = 589/589 (100%)
Query: 1 MDGEAVRFCTDNQCVSLHPQEVDSVAMAPAAPKIPRLVQATPAFMAVTLVFSLVTLFVVV 60
MDGEAVRFCTDNQCVSLHPQEVDSVAMAPAAPKIPRLVQATPAFMAVTLVFSLVTLFVVV
Sbjct: 1 MDGEAVRFCTDNQCVSLHPQEVDSVAMAPAAPKIPRLVQATPAFMAVTLVFSLVTLFVVV 60
Query: 61 QQQTRPVPKPVQAVILGDNITGHLPFEPNNHHHFGREAEMRELIQTFKGHMENSSAWVVE 120
QQQTRPVPKPVQAVILGDNITGHLPFEPNNHHHFGREAEMRELIQTFKGHMENSSAWVVE
Sbjct: 61 QQQTRPVPKPVQAVILGDNITGHLPFEPNNHHHFGREAEMRELIQTFKGHMENSSAWVVE 120
Query: 121 IQMLKCRVDNVNSQLQVLGDHLGNTNADIQMVKGVLKDATTLSLQTQMLRSSLEGTNAEI 180
IQMLKCRVDNVNSQLQVLGDHLGNTNADIQMVKGVLKDATTLSLQTQMLRSSLEGTNAEI
Sbjct: 121 IQMLKCRVDNVNSQLQVLGDHLGNTNADIQMVKGVLKDATTLSLQTQMLRSSLEGTNAEI 180
Query: 181 QRLKEDLEKADALTFQTLNFLKSSLENTSIELHVLSRGLENANSEIQMLNASLETANTQA 240
QRLKEDLEKADALTFQTLNFLKSSLENTSIELHVLSRGLENANSEIQMLNASLETANTQA
Sbjct: 181 QRLKEDLEKADALTFQTLNFLKSSLENTSIELHVLSRGLENANSEIQMLNASLETANTQA 240
Query: 241 QLANSSLKNANAEIYVLRGHLDSVNDLRTQNQVLRNSLEGANAEIQGLKENLQNTNALNS 300
QLANSSLKNANAEIYVLRGHLDSVNDLRTQNQVLRNSLEGANAEIQGLKENLQNTNALNS
Sbjct: 241 QLANSSLKNANAEIYVLRGHLDSVNDLRTQNQVLRNSLEGANAEIQGLKENLQNTNALNS 300
Query: 301 QTQAFIKSSFDNTSAEIQFLRGHLERAGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQ 360
QTQAFIKSSFDNTSAEIQFLRGHLERAGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQ
Sbjct: 301 QTQAFIKSSFDNTSAEIQFLRGHLERAGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQ 360
Query: 361 VFKSEMENVNTLNAQIQVLNGHMKNASREIQTLKQGMKNASALTSQTQMLDSNLQKASAE 420
VFKSEMENVNTLNAQIQVLNGHMKNASREIQTLKQGMKNASALTSQTQMLDSNLQKASAE
Sbjct: 361 VFKSEMENVNTLNAQIQVLNGHMKNASREIQTLKQGMKNASALTSQTQMLDSNLQKASAE 420
Query: 421 IQRLRGDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQRTQSQLLQMVLQGWKFNGGSL 480
IQRLRGDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQRTQSQLLQMVLQGWKFNGGSL
Sbjct: 421 IQRLRGDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQRTQSQLLQMVLQGWKFNGGSL 480
Query: 481 YYFSSVKKSWHEAEQFCVSQGAHLASVASKEEQAFLVEFTSKVYYWIGLTDRGTEGSWRW 540
YYFSSVKKSWHEAEQFCVSQGAHLASVASKEEQAFLVEFTSKVYYWIGLTDRGTEGSWRW
Sbjct: 481 YYFSSVKKSWHEAEQFCVSQGAHLASVASKEEQAFLVEFTSKVYYWIGLTDRGTEGSWRW 540
Query: 541 TDGTPFNAAQNKAPGSKGSCPLRKYIIVNSGMGACSFIDTPPCPWILSN 589
TDGTPFNAAQNKAPGSKGSCPLRKYIIVNSGMGACSFIDTPPCPWILSN
Sbjct: 541 TDGTPFNAAQNKAPGSKGSCPLRKYIIVNSGMGACSFIDTPPCPWILSN 589
>gi|90991712 CD207 antigen, langerin [Homo sapiens]
Length = 328
Score = 148 bits (373), Expect = 2e-35
Identities = 75/212 (35%), Positives = 123/212 (58%), Gaps = 13/212 (6%)
Query: 350 GRLDQTDTQIQVFKSEMENVNTLNAQIQVLNGHMKNASREIQTLKQGMKNASALTSQTQM 409
G + T +Q+ K ++N++TL+++I+ + M+ A +IQ + + + + SQ
Sbjct: 69 GTISDVKTNVQLLKGRVDNISTLDSEIKKNSDGMEAAGVQIQMVNESL---GYVRSQFLK 125
Query: 410 LDSNLQKASAEIQRLRGDLENTKALTMEIQQEQS----------RLKTLHVVITSQEQLQ 459
L ++++KA+A+IQ L E L +I + +S +++ L + + +L
Sbjct: 126 LKTSVEKANAQIQILTRSWEEVSTLNAQIPELKSDLEKASALNTKIRALQGSLENMSKLL 185
Query: 460 RTQSQLLQMVLQGWKFNGGSLYYFSSVKKSWHEAEQFCVSQGAHLASVASKEEQAFLVEF 519
+ Q+ +LQ+V QGWK+ G+ YYFS + K+W+ AEQFCVS+ +HL SV S+ EQ FL +
Sbjct: 186 KRQNDILQVVSQGWKYFKGNFYYFSLIPKTWYSAEQFCVSRNSHLTSVTSESEQEFLYKT 245
Query: 520 TSKVYYWIGLTDRGTEGSWRWTDGTPFNAAQN 551
+ YWIGLT G EG W W D TPFN Q+
Sbjct: 246 AGGLIYWIGLTKAGMEGDWSWVDDTPFNKVQS 277
Score = 51.2 bits (121), Expect = 3e-06
Identities = 57/206 (27%), Positives = 89/206 (43%), Gaps = 39/206 (18%)
Query: 8 FCTDNQCVSLHPQEVDSVAMAPAAPKIPRLVQA-TPAFMAVTLVFSLVTLFVVVQQQTRP 66
F D Q +SL P+E P P LV TP A + +LV + V+
Sbjct: 12 FTVDKQNISLWPRE-------PPPKSGPSLVPGKTPTVRAALICLTLVLVASVL------ 58
Query: 67 VPKPVQAVILGDNITGHLPFEPNNHHHFGREAEMRELIQTFKGHMENSSAWVVEIQMLKC 126
+QAV+ G ++++ +Q KG ++N S EI+
Sbjct: 59 ----LQAVLYP--------------RFMGTISDVKTNVQLLKGRVDNISTLDSEIKKNSD 100
Query: 127 RVDNVNSQLQVLGDHLGNTNADIQMVKGVLKDATTLSLQTQMLRSSLEGT---NAEIQRL 183
++ Q+Q++ + LG + +K ++ A + Q Q+L S E NA+I L
Sbjct: 101 GMEAAGVQIQMVNESLGYVRSQFLKLKTSVEKA---NAQIQILTRSWEEVSTLNAQIPEL 157
Query: 184 KEDLEKADALTFQTLNFLKSSLENTS 209
K DLEKA AL + + L+ SLEN S
Sbjct: 158 KSDLEKASALNTK-IRALQGSLENMS 182
Score = 50.1 bits (118), Expect = 6e-06
Identities = 35/107 (32%), Positives = 58/107 (54%), Gaps = 6/107 (5%)
Query: 198 LNFLKSSLENTSI---ELHVLSRGLENANSEIQMLNASLETANTQAQLANSSLKNANAEI 254
+ LK ++N S E+ S G+E A +IQM+N SL +Q +S++ ANA+I
Sbjct: 78 VQLLKGRVDNISTLDSEIKKNSDGMEAAGVQIQMVNESLGYVRSQFLKLKTSVEKANAQI 137
Query: 255 YVLRGHLDSVNDLRTQNQVLRNSLEGA---NAEIQGLKENLQNTNAL 298
+L + V+ L Q L++ LE A N +I+ L+ +L+N + L
Sbjct: 138 QILTRSWEEVSTLNAQIPELKSDLEKASALNTKIRALQGSLENMSKL 184
Score = 45.8 bits (107), Expect = 1e-04
Identities = 32/140 (22%), Positives = 71/140 (50%), Gaps = 13/140 (9%)
Query: 142 LGNTNADIQMVKGVLKDATTLSLQTQMLRSSLEGTNAEIQRLKEDLEKADALTFQTLNFL 201
+ + ++Q++KG + + +TL + + +E +IQ + E L + + L
Sbjct: 71 ISDVKTNVQLLKGRVDNISTLDSEIKKNSDGMEAAGVQIQMVNESLGYVRSQFLK----L 126
Query: 202 KSSLENTSIELHVLSRGLENANSEIQMLNASLETANTQAQLANSSLKNANAEIYVLRGHL 261
K+S+E + ++ +L+R E E+ LNA + + + A++ N +I L+G L
Sbjct: 127 KTSVEKANAQIQILTRSWE----EVSTLNAQIPELKSDLEKASA----LNTKIRALQGSL 178
Query: 262 DSVND-LRTQNQVLRNSLEG 280
++++ L+ QN +L+ +G
Sbjct: 179 ENMSKLLKRQNDILQVVSQG 198
Score = 41.2 bits (95), Expect = 0.003
Identities = 42/134 (31%), Positives = 64/134 (47%), Gaps = 26/134 (19%)
Query: 219 LENANSEIQMLNASLETANTQAQLANSSLKNANAEIYVLRGHLDSVNDLRTQNQVLRNSL 278
+ +SEI+ + +E A Q Q+ N SL YV R+Q L+ S+
Sbjct: 88 ISTLDSEIKKNSDGMEAAGVQIQMVNESLG------YV-----------RSQFLKLKTSV 130
Query: 279 EGANAEIQGLKENLQNTNALNSQTQAFIKSSFDNTSA---EIQFLRGHLERAGDEIHVLK 335
E ANA+IQ L + + + LN+Q +KS + SA +I+ L+G LE +LK
Sbjct: 131 EKANAQIQILTRSWEEVSTLNAQIPE-LKSDLEKASALNTKIRALQGSLENMS---KLLK 186
Query: 336 R--DLKMVTAQTQK 347
R D+ V +Q K
Sbjct: 187 RQNDILQVVSQGWK 200
>gi|53832016 C-type lectin, superfamily member 14 isoform 2 [Homo
sapiens]
Length = 292
Score = 84.0 bits (206), Expect = 4e-16
Identities = 53/178 (29%), Positives = 85/178 (47%), Gaps = 12/178 (6%)
Query: 388 REIQTLKQGMKNAS--------ALTSQTQMLDSNLQKASAEIQRLRGDLENTKA-LTMEI 438
R++ TL+ N + ALTSQ L+ + AE++ + + + + + + +
Sbjct: 67 RDLVTLRTDFSNFTSNTVAEIQALTSQGSSLEETIASLKAEVEGFKQERQAVHSEMLLRV 126
Query: 439 QQEQSRLKTLHVVITSQEQLQRTQSQLLQMVLQGWKFNGGSLYYFSSVKKSWHEAEQFCV 498
QQ LK L + + S W + S Y+FS SW EAE++C
Sbjct: 127 QQLVQDLKKLTCQVATLNNNGEEASTEGTCCPVNWVEHQDSCYWFSHSGMSWAEAEKYCQ 186
Query: 499 SQGAHLASVASKEEQAFLVEFTSKVYYWIGLTDRGTEGSWRWTDGTPF-NAAQNKAPG 555
+ AHL + S+EEQ F+ ++ Y W+GL+D EG+W+W DGT + QN PG
Sbjct: 187 LKNAHLVVINSREEQNFVQKYLGSAYTWMGLSD--PEGAWKWVDGTDYATGFQNWKPG 242
>gi|18426877 asialoglycoprotein receptor 2 isoform c [Homo sapiens]
Length = 292
Score = 80.9 bits (198), Expect = 3e-15
Identities = 52/163 (31%), Positives = 82/163 (50%), Gaps = 7/163 (4%)
Query: 389 EIQTLKQGMKNASALT-SQTQMLDSNLQKASAEIQRLRGDLENTKA-LTMEIQQEQSRLK 446
E+++LK+ N S+ T ++ Q + ++ +I L LE + L + LK
Sbjct: 73 ELRSLKEAFSNFSSSTLTEVQAISTHGGSVGDKITSLGAKLEKQQQDLKADHDALLFHLK 132
Query: 447 TLHV---VITSQEQLQRTQSQLLQMVLQGWKFNGGSLYYFSSVKKSWHEAEQFCVSQGAH 503
V + Q +L + W + GS Y+FS K+W EAE++C + AH
Sbjct: 133 HFPVDLRFVACQMELLHSNGSQRTCCPVNWVEHQGSCYWFSHSGKAWAEAEKYCQLENAH 192
Query: 504 LASVASKEEQAFLVEFTSKVYYWIGLTDRGTEGSWRWTDGTPF 546
L + S EEQ F+V+ T+ WIGLTD ++GSW+W DGT +
Sbjct: 193 LVVINSWEEQKFIVQHTNPFNTWIGLTD--SDGSWKWVDGTDY 233
>gi|18426875 asialoglycoprotein receptor 2 isoform b [Homo sapiens]
Length = 287
Score = 80.9 bits (198), Expect = 3e-15
Identities = 52/163 (31%), Positives = 82/163 (50%), Gaps = 7/163 (4%)
Query: 389 EIQTLKQGMKNASALT-SQTQMLDSNLQKASAEIQRLRGDLENTKA-LTMEIQQEQSRLK 446
E+++LK+ N S+ T ++ Q + ++ +I L LE + L + LK
Sbjct: 68 ELRSLKEAFSNFSSSTLTEVQAISTHGGSVGDKITSLGAKLEKQQQDLKADHDALLFHLK 127
Query: 447 TLHV---VITSQEQLQRTQSQLLQMVLQGWKFNGGSLYYFSSVKKSWHEAEQFCVSQGAH 503
V + Q +L + W + GS Y+FS K+W EAE++C + AH
Sbjct: 128 HFPVDLRFVACQMELLHSNGSQRTCCPVNWVEHQGSCYWFSHSGKAWAEAEKYCQLENAH 187
Query: 504 LASVASKEEQAFLVEFTSKVYYWIGLTDRGTEGSWRWTDGTPF 546
L + S EEQ F+V+ T+ WIGLTD ++GSW+W DGT +
Sbjct: 188 LVVINSWEEQKFIVQHTNPFNTWIGLTD--SDGSWKWVDGTDY 228
>gi|18426873 asialoglycoprotein receptor 2 isoform a [Homo sapiens]
Length = 311
Score = 80.9 bits (198), Expect = 3e-15
Identities = 52/163 (31%), Positives = 82/163 (50%), Gaps = 7/163 (4%)
Query: 389 EIQTLKQGMKNASALT-SQTQMLDSNLQKASAEIQRLRGDLENTKA-LTMEIQQEQSRLK 446
E+++LK+ N S+ T ++ Q + ++ +I L LE + L + LK
Sbjct: 92 ELRSLKEAFSNFSSSTLTEVQAISTHGGSVGDKITSLGAKLEKQQQDLKADHDALLFHLK 151
Query: 447 TLHV---VITSQEQLQRTQSQLLQMVLQGWKFNGGSLYYFSSVKKSWHEAEQFCVSQGAH 503
V + Q +L + W + GS Y+FS K+W EAE++C + AH
Sbjct: 152 HFPVDLRFVACQMELLHSNGSQRTCCPVNWVEHQGSCYWFSHSGKAWAEAEKYCQLENAH 211
Query: 504 LASVASKEEQAFLVEFTSKVYYWIGLTDRGTEGSWRWTDGTPF 546
L + S EEQ F+V+ T+ WIGLTD ++GSW+W DGT +
Sbjct: 212 LVVINSWEEQKFIVQHTNPFNTWIGLTD--SDGSWKWVDGTDY 252
>gi|4502253 asialoglycoprotein receptor 2 isoform a [Homo sapiens]
Length = 311
Score = 80.9 bits (198), Expect = 3e-15
Identities = 52/163 (31%), Positives = 82/163 (50%), Gaps = 7/163 (4%)
Query: 389 EIQTLKQGMKNASALT-SQTQMLDSNLQKASAEIQRLRGDLENTKA-LTMEIQQEQSRLK 446
E+++LK+ N S+ T ++ Q + ++ +I L LE + L + LK
Sbjct: 92 ELRSLKEAFSNFSSSTLTEVQAISTHGGSVGDKITSLGAKLEKQQQDLKADHDALLFHLK 151
Query: 447 TLHV---VITSQEQLQRTQSQLLQMVLQGWKFNGGSLYYFSSVKKSWHEAEQFCVSQGAH 503
V + Q +L + W + GS Y+FS K+W EAE++C + AH
Sbjct: 152 HFPVDLRFVACQMELLHSNGSQRTCCPVNWVEHQGSCYWFSHSGKAWAEAEKYCQLENAH 211
Query: 504 LASVASKEEQAFLVEFTSKVYYWIGLTDRGTEGSWRWTDGTPF 546
L + S EEQ F+V+ T+ WIGLTD ++GSW+W DGT +
Sbjct: 212 LVVINSWEEQKFIVQHTNPFNTWIGLTD--SDGSWKWVDGTDY 252
>gi|223278342 C-type lectin domain family 4, member M isoform 11
[Homo sapiens]
Length = 332
Score = 80.1 bits (196), Expect = 5e-15
Identities = 60/226 (26%), Positives = 106/226 (46%), Gaps = 24/226 (10%)
Query: 343 AQTQKANGRLDQTDTQIQVF------KSEMENVNTLNAQIQVLNGHMKNASREIQTLKQG 396
+Q Q + Q TQ++ KS+++ + Q++ G + S+ +Q + Q
Sbjct: 59 SQEQSEQDAIYQNLTQLKAAVGELSEKSKLQEIYQELTQLKAAVGELPEKSK-LQEIYQE 117
Query: 397 MKNASALTSQTQMLDSNLQKASAEIQRLR---GDLENTKALTMEIQQEQSRLKTLHVVIT 453
+ A + S LQ+ E+ RL+ G+L K+ EI QE + LK +
Sbjct: 118 LTRLKAAVGELPE-KSKLQEIYQELTRLKAAVGELPE-KSKLQEIYQELTELKAAVGELP 175
Query: 454 SQEQLQRTQSQLLQMVL----------QGWKFNGGSLYYFSSVKKSWHEAEQFCVSQGAH 503
+ +LQ +L Q+ + W F G+ Y+ S+ +++WH++ C A
Sbjct: 176 EKSKLQEIYQELTQLKAAVERLCRHCPKDWTFFQGNCYFMSNSQRNWHDSVTACQEVRAQ 235
Query: 504 LASVASKEEQAFLVEFTSKV--YYWIGLTDRGTEGSWRWTDGTPFN 547
L + + EEQ FL TS+ + W+GL+D EG+W+W DG+P +
Sbjct: 236 LVVIKTAEEQNFLQLQTSRSNRFSWMGLSDLNQEGTWQWVDGSPLS 281
>gi|223278347 C-type lectin domain family 4, member M isoform 9
[Homo sapiens]
Length = 353
Score = 78.2 bits (191), Expect = 2e-14
Identities = 59/226 (26%), Positives = 106/226 (46%), Gaps = 24/226 (10%)
Query: 343 AQTQKANGRLDQTDTQIQVF------KSEMENVNTLNAQIQVLNGHMKNASREIQTLKQG 396
+Q Q + Q TQ++ KS+++ + Q++ G + S+ +Q + Q
Sbjct: 80 SQEQSEQDAIYQNLTQLKAAVGELSEKSKLQEIYQELTQLKAAVGELPEKSK-LQEIYQE 138
Query: 397 MKNASALTSQTQMLDSNLQKASAEIQRLR---GDLENTKALTMEIQQEQSRLKTLHVVIT 453
+ A + S LQ+ E+ RL+ G+L K+ EI QE ++LK +
Sbjct: 139 LTRLKAAVGELPE-KSKLQEIYQELTRLKAAVGELPE-KSKLQEIYQELTQLKAAVGELP 196
Query: 454 SQEQLQRTQSQLLQMVL----------QGWKFNGGSLYYFSSVKKSWHEAEQFCVSQGAH 503
Q + Q+ +L + + W F G+ Y+ S+ +++WH++ C A
Sbjct: 197 DQSKQQQIYQELTDLKTAFERLCRHCPKDWTFFQGNCYFMSNSQRNWHDSVTACQEVRAQ 256
Query: 504 LASVASKEEQAFLVEFTSKV--YYWIGLTDRGTEGSWRWTDGTPFN 547
L + + EEQ FL TS+ + W+GL+D EG+W+W DG+P +
Sbjct: 257 LVVIKTAEEQNFLQLQTSRSNRFSWMGLSDLNQEGTWQWVDGSPLS 302
>gi|223278339 C-type lectin domain family 4, member M isoform 7
[Homo sapiens]
Length = 263
Score = 76.3 bits (186), Expect = 8e-14
Identities = 53/207 (25%), Positives = 101/207 (48%), Gaps = 24/207 (11%)
Query: 353 DQTDTQIQVFKSEMENVNTLNAQIQVLNGHMKNA--------SREIQTLKQGMKNASALT 404
D T + I++F + Q Q ++GH + S+ +L Q A+
Sbjct: 18 DPTTSGIRLFPRDF--------QFQQIHGHKSSTVPFLLGPVSKVPSSLSQEQSEQDAIY 69
Query: 405 SQTQMLDSNLQKAS--AEIQRLRGDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQRTQ 462
L + + + S +++Q + +L KA E+ E+S+L+ ++ +T +L+
Sbjct: 70 QNLTQLKAAVGELSEKSKLQEIYQELTQLKAAVGELP-EKSKLQEIYQELT---RLKAAV 125
Query: 463 SQLLQMVLQGWKFNGGSLYYFSSVKKSWHEAEQFCVSQGAHLASVASKEEQAFLVEFTSK 522
+L + + W F G+ Y+ S+ +++WH++ C A L + + EEQ FL TS+
Sbjct: 126 ERLCRHCPKDWTFFQGNCYFMSNSQRNWHDSVTACQEVRAQLVVIKTAEEQNFLQLQTSR 185
Query: 523 V--YYWIGLTDRGTEGSWRWTDGTPFN 547
+ W+GL+D EG+W+W DG+P +
Sbjct: 186 SNRFSWMGLSDLNQEGTWQWVDGSPLS 212
>gi|33667103 C-type lectin, superfamily member 14 isoform 1 [Homo
sapiens]
Length = 316
Score = 76.3 bits (186), Expect = 8e-14
Identities = 60/206 (29%), Positives = 92/206 (44%), Gaps = 44/206 (21%)
Query: 388 REIQTLKQGMKNAS--------ALTSQTQMLDSNLQKASAEIQRLRGDLENTKALTMEIQ 439
R++ TL+ N + ALTSQ L+ + AE++ G + +A E+Q
Sbjct: 67 RDLVTLRTDFSNFTSNTVAEIQALTSQGSSLEETIASLKAEVE---GFKQERQAGVSELQ 123
Query: 440 QEQSRLKTLH--------VVITSQEQLQRTQSQLLQMVLQ-------------------- 471
+ ++ L V E L R Q QL+Q + +
Sbjct: 124 EHTTQKAHLGHCPHCPSVCVPVHSEMLLRVQ-QLVQDLKKLTCQVATLNNNASTEGTCCP 182
Query: 472 -GWKFNGGSLYYFSSVKKSWHEAEQFCVSQGAHLASVASKEEQAFLVEFTSKVYYWIGLT 530
W + S Y+FS SW EAE++C + AHL + S+EEQ F+ ++ Y W+GL+
Sbjct: 183 VNWVEHQDSCYWFSHSGMSWAEAEKYCQLKNAHLVVINSREEQNFVQKYLGSAYTWMGLS 242
Query: 531 DRGTEGSWRWTDGTPF-NAAQNKAPG 555
D EG+W+W DGT + QN PG
Sbjct: 243 D--PEGAWKWVDGTDYATGFQNWKPG 266
>gi|223029517 CD209 molecule isoform 8 [Homo sapiens]
Length = 243
Score = 75.5 bits (184), Expect = 1e-13
Identities = 42/124 (33%), Positives = 65/124 (52%), Gaps = 5/124 (4%)
Query: 424 LRGDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQRTQSQLLQMVLQGWKFNGGSLYYF 483
L G L + I QEQSR ++ +T QL+ +L W F G+ Y+
Sbjct: 53 LAGLLVQVSKVPSSISQEQSRQDAIYQNLT---QLKAAVERLCHPCPWEWTFFQGNCYFM 109
Query: 484 SSVKKSWHEAEQFCVSQGAHLASVASKEEQAFLVEFTSKV--YYWIGLTDRGTEGSWRWT 541
S+ +++WH++ C GA L + S EEQ FL +S+ + W+GL+D EG+W+W
Sbjct: 110 SNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNRFTWMGLSDLNQEGTWQWV 169
Query: 542 DGTP 545
DG+P
Sbjct: 170 DGSP 173
>gi|223029384 CD209 molecule isoform 7 [Homo sapiens]
Length = 312
Score = 75.1 bits (183), Expect = 2e-13
Identities = 48/149 (32%), Positives = 79/149 (53%), Gaps = 16/149 (10%)
Query: 412 SNLQKASAEIQRLR---GDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQRTQSQL--L 466
S LQ+ E+ +L+ G+L K+ EI QE +RLK + + +LQ +L L
Sbjct: 95 SKLQEIYQELTQLKAAVGELPE-KSKLQEIYQELTRLKAAVGELPEKSKLQEIYQELTWL 153
Query: 467 QMVLQG--------WKFNGGSLYYFSSVKKSWHEAEQFCVSQGAHLASVASKEEQAFLVE 518
+ ++ W F G+ Y+ S+ +++WH++ C GA L + S EEQ FL
Sbjct: 154 KAAVERLCHPCPWEWTFFQGNCYFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQL 213
Query: 519 FTSKV--YYWIGLTDRGTEGSWRWTDGTP 545
+S+ + W+GL+D EG+W+W DG+P
Sbjct: 214 QSSRSNRFTWMGLSDLNQEGTWQWVDGSP 242
>gi|223029380 CD209 molecule isoform 5 [Homo sapiens]
Length = 268
Score = 75.1 bits (183), Expect = 2e-13
Identities = 48/149 (32%), Positives = 79/149 (53%), Gaps = 16/149 (10%)
Query: 412 SNLQKASAEIQRLR---GDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQRTQSQL--L 466
S LQ+ E+ +L+ G+L K+ EI QE +RLK + + +LQ +L L
Sbjct: 51 SKLQEIYQELTQLKAAVGELPE-KSKLQEIYQELTRLKAAVGELPEKSKLQEIYQELTWL 109
Query: 467 QMVLQG--------WKFNGGSLYYFSSVKKSWHEAEQFCVSQGAHLASVASKEEQAFLVE 518
+ ++ W F G+ Y+ S+ +++WH++ C GA L + S EEQ FL
Sbjct: 110 KAAVERLCHPCPWEWTFFQGNCYFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQL 169
Query: 519 FTSKV--YYWIGLTDRGTEGSWRWTDGTP 545
+S+ + W+GL+D EG+W+W DG+P
Sbjct: 170 QSSRSNRFTWMGLSDLNQEGTWQWVDGSP 198
>gi|223029386 CD209 molecule isoform 3 [Homo sapiens]
Length = 380
Score = 74.7 bits (182), Expect = 2e-13
Identities = 54/198 (27%), Positives = 94/198 (47%), Gaps = 18/198 (9%)
Query: 363 KSEMENVNTLNAQIQVLNGHMKNASREIQTLKQGMKNASALTSQTQMLDSNLQKASAEIQ 422
KS+++ + ++ G + S+ +Q + Q + A + S Q+ E+
Sbjct: 116 KSKLQEIYQELTWLKAAVGELPEKSK-MQEIYQELTRLKAAVGELPE-KSKQQEIYQELT 173
Query: 423 RLR---GDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQRTQSQLLQMVLQ-------- 471
RL+ G+L K+ EI QE +RLK + + + Q +L Q+
Sbjct: 174 RLKAAVGELPE-KSKQQEIYQELTRLKAAVGELPEKSKQQEIYQELTQLKAAVERLCHPC 232
Query: 472 --GWKFNGGSLYYFSSVKKSWHEAEQFCVSQGAHLASVASKEEQAFLVEFTSKV--YYWI 527
W F G+ Y+ S+ +++WH++ C GA L + S EEQ FL +S+ + W+
Sbjct: 233 PWEWTFFQGNCYFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNRFTWM 292
Query: 528 GLTDRGTEGSWRWTDGTP 545
GL+D EG+W+W DG+P
Sbjct: 293 GLSDLNQEGTWQWVDGSP 310
>gi|223029382 CD209 molecule isoform 6 [Homo sapiens]
Length = 360
Score = 74.7 bits (182), Expect = 2e-13
Identities = 54/198 (27%), Positives = 94/198 (47%), Gaps = 18/198 (9%)
Query: 363 KSEMENVNTLNAQIQVLNGHMKNASREIQTLKQGMKNASALTSQTQMLDSNLQKASAEIQ 422
KS+++ + ++ G + S+ +Q + Q + A + S Q+ E+
Sbjct: 96 KSKLQEIYQELTWLKAAVGELPEKSK-MQEIYQELTRLKAAVGELPE-KSKQQEIYQELT 153
Query: 423 RLR---GDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQRTQSQLLQMVLQ-------- 471
RL+ G+L K+ EI QE +RLK + + + Q +L Q+
Sbjct: 154 RLKAAVGELPE-KSKQQEIYQELTRLKAAVGELPEKSKQQEIYQELTQLKAAVERLCHPC 212
Query: 472 --GWKFNGGSLYYFSSVKKSWHEAEQFCVSQGAHLASVASKEEQAFLVEFTSKV--YYWI 527
W F G+ Y+ S+ +++WH++ C GA L + S EEQ FL +S+ + W+
Sbjct: 213 PWEWTFFQGNCYFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNRFTWM 272
Query: 528 GLTDRGTEGSWRWTDGTP 545
GL+D EG+W+W DG+P
Sbjct: 273 GLSDLNQEGTWQWVDGSP 290
>gi|10863957 CD209 molecule isoform 1 [Homo sapiens]
Length = 404
Score = 74.7 bits (182), Expect = 2e-13
Identities = 54/198 (27%), Positives = 94/198 (47%), Gaps = 18/198 (9%)
Query: 363 KSEMENVNTLNAQIQVLNGHMKNASREIQTLKQGMKNASALTSQTQMLDSNLQKASAEIQ 422
KS+++ + ++ G + S+ +Q + Q + A + S Q+ E+
Sbjct: 140 KSKLQEIYQELTWLKAAVGELPEKSK-MQEIYQELTRLKAAVGELPE-KSKQQEIYQELT 197
Query: 423 RLR---GDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQRTQSQLLQMVLQ-------- 471
RL+ G+L K+ EI QE +RLK + + + Q +L Q+
Sbjct: 198 RLKAAVGELPE-KSKQQEIYQELTRLKAAVGELPEKSKQQEIYQELTQLKAAVERLCHPC 256
Query: 472 --GWKFNGGSLYYFSSVKKSWHEAEQFCVSQGAHLASVASKEEQAFLVEFTSKV--YYWI 527
W F G+ Y+ S+ +++WH++ C GA L + S EEQ FL +S+ + W+
Sbjct: 257 PWEWTFFQGNCYFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNRFTWM 316
Query: 528 GLTDRGTEGSWRWTDGTP 545
GL+D EG+W+W DG+P
Sbjct: 317 GLSDLNQEGTWQWVDGSP 334
>gi|223278337 C-type lectin domain family 4, member M isoform 12
[Homo sapiens]
Length = 375
Score = 74.3 bits (181), Expect = 3e-13
Identities = 52/200 (26%), Positives = 96/200 (48%), Gaps = 18/200 (9%)
Query: 363 KSEMENVNTLNAQIQVLNGHMKNASREIQTLKQGMKNASALTSQTQMLDSNLQKASAEIQ 422
KS+++ + +++ G + S+ +Q + Q + A + S LQ+ E+
Sbjct: 128 KSKLQEIYQELTRLKAAVGELPEKSK-LQEIYQELTRLKAAVGELPE-KSKLQEIYQELT 185
Query: 423 RLR---GDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQRTQSQLLQMVL--------- 470
L+ G+L K+ EI QE ++LK + Q + Q+ +L +
Sbjct: 186 ELKAAVGELPE-KSKLQEIYQELTQLKAAVGELPDQSKQQQIYQELTDLKTAFERLCRHC 244
Query: 471 -QGWKFNGGSLYYFSSVKKSWHEAEQFCVSQGAHLASVASKEEQAFLVEFTSKV--YYWI 527
+ W F G+ Y+ S+ +++WH++ C A L + + EEQ FL TS+ + W+
Sbjct: 245 PKDWTFFQGNCYFMSNSQRNWHDSVTACQEVRAQLVVIKTAEEQNFLQLQTSRSNRFSWM 304
Query: 528 GLTDRGTEGSWRWTDGTPFN 547
GL+D EG+W+W DG+P +
Sbjct: 305 GLSDLNQEGTWQWVDGSPLS 324
>gi|223278335 C-type lectin domain family 4, member M isoform 2
[Homo sapiens]
Length = 348
Score = 74.3 bits (181), Expect = 3e-13
Identities = 52/200 (26%), Positives = 96/200 (48%), Gaps = 18/200 (9%)
Query: 363 KSEMENVNTLNAQIQVLNGHMKNASREIQTLKQGMKNASALTSQTQMLDSNLQKASAEIQ 422
KS+++ + +++ G + S+ +Q + Q + A + S LQ+ E+
Sbjct: 101 KSKLQEIYQELTRLKAAVGELPEKSK-LQEIYQELTRLKAAVGELPE-KSKLQEIYQELT 158
Query: 423 RLR---GDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQRTQSQLLQMVL--------- 470
L+ G+L K+ EI QE ++LK + Q + Q+ +L +
Sbjct: 159 ELKAAVGELPE-KSKLQEIYQELTQLKAAVGELPDQSKQQQIYQELTDLKTAFERLCRHC 217
Query: 471 -QGWKFNGGSLYYFSSVKKSWHEAEQFCVSQGAHLASVASKEEQAFLVEFTSKV--YYWI 527
+ W F G+ Y+ S+ +++WH++ C A L + + EEQ FL TS+ + W+
Sbjct: 218 PKDWTFFQGNCYFMSNSQRNWHDSVTACQEVRAQLVVIKTAEEQNFLQLQTSRSNRFSWM 277
Query: 528 GLTDRGTEGSWRWTDGTPFN 547
GL+D EG+W+W DG+P +
Sbjct: 278 GLSDLNQEGTWQWVDGSPLS 297
>gi|223278350 C-type lectin domain family 4, member M isoform 8
[Homo sapiens]
Length = 376
Score = 74.3 bits (181), Expect = 3e-13
Identities = 52/200 (26%), Positives = 96/200 (48%), Gaps = 18/200 (9%)
Query: 363 KSEMENVNTLNAQIQVLNGHMKNASREIQTLKQGMKNASALTSQTQMLDSNLQKASAEIQ 422
KS+++ + +++ G + S+ +Q + Q + A + S LQ+ E+
Sbjct: 129 KSKLQEIYQELTRLKAAVGELPEKSK-LQEIYQELTRLKAAVGELPE-KSKLQEIYQELT 186
Query: 423 RLR---GDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQRTQSQLLQMVL--------- 470
L+ G+L K+ EI QE ++LK + Q + Q+ +L +
Sbjct: 187 ELKAAVGELPE-KSKLQEIYQELTQLKAAVGELPDQSKQQQIYQELTDLKTAFERLCRHC 245
Query: 471 -QGWKFNGGSLYYFSSVKKSWHEAEQFCVSQGAHLASVASKEEQAFLVEFTSKV--YYWI 527
+ W F G+ Y+ S+ +++WH++ C A L + + EEQ FL TS+ + W+
Sbjct: 246 PKDWTFFQGNCYFMSNSQRNWHDSVTACQEVRAQLVVIKTAEEQNFLQLQTSRSNRFSWM 305
Query: 528 GLTDRGTEGSWRWTDGTPFN 547
GL+D EG+W+W DG+P +
Sbjct: 306 GLSDLNQEGTWQWVDGSPLS 325
>gi|42542390 C-type lectin domain family 4, member M isoform 1 [Homo
sapiens]
Length = 399
Score = 74.3 bits (181), Expect = 3e-13
Identities = 52/200 (26%), Positives = 96/200 (48%), Gaps = 18/200 (9%)
Query: 363 KSEMENVNTLNAQIQVLNGHMKNASREIQTLKQGMKNASALTSQTQMLDSNLQKASAEIQ 422
KS+++ + +++ G + S+ +Q + Q + A + S LQ+ E+
Sbjct: 152 KSKLQEIYQELTRLKAAVGELPEKSK-LQEIYQELTRLKAAVGELPE-KSKLQEIYQELT 209
Query: 423 RLR---GDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQRTQSQLLQMVL--------- 470
L+ G+L K+ EI QE ++LK + Q + Q+ +L +
Sbjct: 210 ELKAAVGELPE-KSKLQEIYQELTQLKAAVGELPDQSKQQQIYQELTDLKTAFERLCRHC 268
Query: 471 -QGWKFNGGSLYYFSSVKKSWHEAEQFCVSQGAHLASVASKEEQAFLVEFTSKV--YYWI 527
+ W F G+ Y+ S+ +++WH++ C A L + + EEQ FL TS+ + W+
Sbjct: 269 PKDWTFFQGNCYFMSNSQRNWHDSVTACQEVRAQLVVIKTAEEQNFLQLQTSRSNRFSWM 328
Query: 528 GLTDRGTEGSWRWTDGTPFN 547
GL+D EG+W+W DG+P +
Sbjct: 329 GLSDLNQEGTWQWVDGSPLS 348
>gi|38372935 brevican isoform 1 [Homo sapiens]
Length = 911
Score = 72.0 bits (175), Expect = 1e-12
Identities = 38/88 (43%), Positives = 49/88 (55%), Gaps = 2/88 (2%)
Query: 472 GWKFNGGSLYYFSSVKKSWHEAEQFCVSQGAHLASVASKEEQAFLVEFTSKVYYWIGLTD 531
GW G+ Y S ++SW EAE C GAHLAS+++ EEQ F + + Y WIGL D
Sbjct: 691 GWDAFQGACYKHFSTRRSWEEAETQCRMYGAHLASISTPEEQDF-INNRYREYQWIGLND 749
Query: 532 RGTEGSWRWTDGTPFNAAQNKAPGSKGS 559
R EG + W+DG P +N PG S
Sbjct: 750 RTIEGDFLWSDGVPL-LYENWNPGQPDS 776
>gi|223029388 CD209 molecule isoform 4 [Homo sapiens]
Length = 398
Score = 71.6 bits (174), Expect = 2e-12
Identities = 52/196 (26%), Positives = 91/196 (46%), Gaps = 20/196 (10%)
Query: 363 KSEMENVNTLNAQIQVLNGHMKNASREIQTLKQGMKNASALTSQTQMLDSNLQKASAEIQ 422
KS+++ + ++ G + S+ +Q + Q + A + S Q+ E+
Sbjct: 140 KSKLQEIYQELTWLKAAVGELPEKSK-MQEIYQELTRLKAAVGELPE-KSKQQEIYQELT 197
Query: 423 RLR---GDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQRTQSQLLQMVLQ-------- 471
RL+ G+L K+ EI QE +RLK + + + Q +L Q+
Sbjct: 198 RLKAAVGELPE-KSKQQEIYQELTRLKAAVGELPEKSKQQEIYQELTQLKAAVERLCHPC 256
Query: 472 --GWKFNGGSLYYFSSVKKSWHEAEQFCVSQGAHLASVASKEEQAFLVEFTSKVYYWIGL 529
W F G+ Y+ S+ +++WH++ C GA L + S EEQ+ S + W+GL
Sbjct: 257 PWEWTFFQGNCYFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQS----SRSNRFTWMGL 312
Query: 530 TDRGTEGSWRWTDGTP 545
+D EG+W+W DG+P
Sbjct: 313 SDLNQEGTWQWVDGSP 328
>gi|31542313 C-type lectin domain family 4, member D [Homo sapiens]
Length = 215
Score = 69.3 bits (168), Expect = 9e-12
Identities = 28/76 (36%), Positives = 48/76 (63%), Gaps = 1/76 (1%)
Query: 473 WKFNGGSLYYFSSVKKSWHEAEQFCVSQGAHLASVASKEEQAFLVEFTS-KVYYWIGLTD 531
W+ + Y+ + K+W E+E+ C GAHL +++++ EQ F+++F ++ Y++GL D
Sbjct: 88 WRAFQSNCYFPLTDNKTWAESERNCSGMGAHLMTISTEAEQNFIIQFLDRRLSYFLGLRD 147
Query: 532 RGTEGSWRWTDGTPFN 547
+G WRW D TPFN
Sbjct: 148 ENAKGQWRWVDQTPFN 163
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 68.6 bits (166), Expect = 2e-11
Identities = 82/423 (19%), Positives = 175/423 (41%), Gaps = 66/423 (15%)
Query: 95 GREAEMRELIQTFKGHMENSSAWVVEI-QMLKCRVDNVNSQLQVLGDHLGNTNADIQMVK 153
G+ +E+ +L+ +FK +E ++I + K V+ + +QL+ L + + D +++K
Sbjct: 2224 GQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMK 2283
Query: 154 GVLKDATTLSLQTQMLRSSLEGTNAEI-----------QRLKEDLEKADALTFQTLNFLK 202
+ + LR+S+E A + Q+LKE AD LK
Sbjct: 2284 ATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHAD--------LLK 2335
Query: 203 SSLENTSIELHVLSRGLENANSEIQMLNASLETANTQAQLANSSLKNANAEIYVLRGHLD 262
+EN EL + E+A E + +ET + + SL+ ++ +R +
Sbjct: 2336 GRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKE 2395
Query: 263 SVNDLRTQNQVLRNSLEGANAEIQG--------------------------LKENLQNTN 296
++ + + Q + LE N+ + LKE +
Sbjct: 2396 NLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVA 2455
Query: 297 ALNSQTQAFIKSSFDNTSAEI--------QFLRGHLERAGDEIHVLKRDLKMVTAQTQKA 348
AL++ +A K+ N S+++ Q L+G L+ A + VL+ + + + +
Sbjct: 2456 ALHNDQEA-CKAKEQNLSSQVECLELEKAQLLQG-LDEAKNNYIVLQSSVNGLIQEVEDG 2513
Query: 349 NGRLDQTDTQIQVFKSEMENVNTLNAQIQVLNGH---MKNASREIQTLKQGM-KNASALT 404
+L++ D +I K+++++ L +++ + G K + E++ L + + L
Sbjct: 2514 KQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQ 2573
Query: 405 SQTQMLDSNLQKASAEIQRLRGDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQRTQSQ 464
S+ L L+ + + L +LE TK + S ++ ++ + + +LQR +
Sbjct: 2574 SKNASLQDTLEVLQSSYKNLENELELTK------MDKMSFVEKVNKMTAKETELQREMHE 2627
Query: 465 LLQ 467
+ Q
Sbjct: 2628 MAQ 2630
Score = 60.1 bits (144), Expect = 6e-09
Identities = 79/355 (22%), Positives = 146/355 (41%), Gaps = 39/355 (10%)
Query: 108 KGHMENSSAWVVEIQMLKCRVDNVNSQLQVLGDHLGNTNADIQMVKGVLKDATTLSLQTQ 167
+G ++ S + L + + + Q L H IQ+ + +K+ T L
Sbjct: 1964 RGELDTMSKKTTALDQLS---EKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLS 2020
Query: 168 MLRSSLEGTNAEIQRLKEDLEKADALTFQTLNFLKSSLENTSIELH----VLSRGLEN-- 221
S L +Q + LEK Q L+ K LEN +L+ +L + E+
Sbjct: 2021 SDVSELLKDKTHLQEKLQSLEKDS----QALSLTKCELENQIAQLNKEKELLVKESESLQ 2076
Query: 222 ---ANSEIQMLNAS--LETANTQAQLANSSLKNANAEIYVLRGHLDSVN-----DLRTQN 271
+ S+ + LN S LE A + L + E++ LR ++ + D + Q
Sbjct: 2077 ARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQL 2136
Query: 272 QVLRN--SLEGANAEIQGLKENLQNTNALNSQTQAFIKSSFDNTSAEIQFLRGHLERAGD 329
+ E N ++ ENL+ ++ + Q + +N+ AE++ L+ +E
Sbjct: 2137 HIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMAR 2196
Query: 330 EIHVLKRDL-------KMVTAQTQKANGRLDQTDTQIQVFKSEMENVNTLNAQIQVLNGH 382
+ V + DL + +T Q Q+ G+L + D + FKS +E A+IQ+
Sbjct: 2197 SLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKE--QAEIQI-KEE 2253
Query: 383 MKNASREIQT-LKQGMKNASALTSQTQMLDSNLQKASAEIQ---RLRGDLENTKA 433
K A +Q LK+ + +AL +++ + Q I+ +LR +E +A
Sbjct: 2254 SKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRA 2308
Score = 54.3 bits (129), Expect = 3e-07
Identities = 92/459 (20%), Positives = 178/459 (38%), Gaps = 55/459 (11%)
Query: 95 GREAEMRELIQTFKG---HMENSSAWVVEIQML--KCRVDNVNSQLQVLGDHLGNTNADI 149
G E EM+ + F+ +E + ++E + + KCR + V + Q T +
Sbjct: 303 GHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALE- 361
Query: 150 QMVKGVLKDATTLSLQTQMLRSSLEGTNAEIQRLKEDLEKADALTFQTLNF--------L 201
Q +K + +D + + R SLE E ++ ++ +FQTL+ L
Sbjct: 362 QKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARL 421
Query: 202 KSSLENTSIELHVLSRGLENANSEIQMLNASLETANTQAQLANSSLKNANAEIYVLRGHL 261
L+ +VL L+ S Q L +LE + A + + + + LR
Sbjct: 422 TQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRR-- 479
Query: 262 DSVNDLRTQNQVLRNSLEGANAEIQGLKENLQNTNALNSQTQAFIKSSFDNTSAEIQFLR 321
S+ +++ +N +L++ E E+ L+ L+N +Q+Q F + +++ LR
Sbjct: 480 -SMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLR 538
Query: 322 GHLERAGDEIHVLKRD-LKMVTAQTQKANGRLDQTDTQIQVFKSEMENVNTLNAQI---- 376
E+ + + L + LK+ A +K Q D + K ++ LN ++
Sbjct: 539 DLQEKINQQENSLTLEKLKLAVADLEK------QRDCSQDLLKKREHHIEQLNDKLSKTE 592
Query: 377 ---QVLNGHMKNASREIQTLKQGMKNASALTSQTQMLDSNLQKASAEIQRLRGDLE---- 429
+ L ++ +E + LK+ S S+ + L + ++ +Q LE
Sbjct: 593 KESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLK 652
Query: 430 ---------NTKALTMEIQQE--QSRLKTLHVVITSQEQLQRTQSQLLQMVLQGWKFNGG 478
N + T+E+ +E ++ LH V+ S+ TQ + Q +F
Sbjct: 653 TQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEF--- 709
Query: 479 SLYYFSSVKKSWHEAEQFCVSQGAHLASVASKEEQAFLV 517
S +K E E C+ V E + L+
Sbjct: 710 ------SDQKHQKEIENMCLKTSQLTGQVEDLEHKLQLL 742
Score = 45.8 bits (107), Expect = 1e-04
Identities = 95/467 (20%), Positives = 186/467 (39%), Gaps = 67/467 (14%)
Query: 102 ELIQT-FKGHMENSSAWVVEIQMLKCRVDNVNSQLQVLGDHLGNTNADIQMVKG---VLK 157
E++QT K E +A + + K + N++SQ++ L + K VL+
Sbjct: 2441 EMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQ 2500
Query: 158 DATT-LSLQTQMLRSSLEGTNAEIQRLKEDLEKADALT--FQTLNFLKSSLENTSIELHV 214
+ L + + + LE + EI RLK ++ + L + + ++EL
Sbjct: 2501 SSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRN 2560
Query: 215 LSRGLENANSEIQMLNASLETANTQAQLANSSLKNANAEIYVLR----GHLDSVNDLRTQ 270
L+ LE +Q NASL+ ++ SS KN E+ + + ++ VN + +
Sbjct: 2561 LTVELEQKIQVLQSKNASLQDT---LEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAK 2617
Query: 271 NQVLRNSLEGANAEIQGLKENLQNT-NALNSQTQAF---IKSSFDNTSAEIQFLRGHLER 326
L+ + + L+E L N L + Q IKSS D E+ L++
Sbjct: 2618 ETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLK-ELTLENSELKK 2676
Query: 327 AGDEIH-------------VLKRDLKMVTAQTQKANGRLD---QTDTQIQVFKSEM---- 366
+ D +H + + L++ A+ + LD Q + +IQ ++ ++
Sbjct: 2677 SLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKE 2736
Query: 367 ------------------ENVNTLNAQIQVLNGHMKNASREIQTLKQGMKNASALTSQTQ 408
E N+L A Q+L K ++ + Q K + +
Sbjct: 2737 ECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMK 2796
Query: 409 MLDSNLQKASAEIQRLRGDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQRTQSQLLQM 468
+L + ++ E + L+ +L ++Q Q + KT V+ T ++L +L +
Sbjct: 2797 LLIKSCKQLEEEKEILQKELS-------QLQAAQEKQKTGTVMDTKVDELTTEIKELKET 2849
Query: 469 VLQGWKFNGGSLYYFSSV---KKSWHEAEQFCVSQGAHLASVASKEE 512
+ + K L + S+ + +A++ +Q AHL S SK++
Sbjct: 2850 LEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQVAHLCSQQSKQD 2896
Score = 45.4 bits (106), Expect = 1e-04
Identities = 69/335 (20%), Positives = 139/335 (41%), Gaps = 51/335 (15%)
Query: 164 LQTQMLRSSLEGTNAEIQRLKEDLEKADALTFQTLNFLKSSLENTSIELHVLSRGLENAN 223
+QT+ L LE N Q++ LE+ ++ N L+ L+ S + L + E
Sbjct: 1928 VQTEKL--CLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMK 1985
Query: 224 SEIQMLNASLETANTQAQLANSSLKNANAEIYVLRGHLDSVNDLRTQNQVLRNSLEGANA 283
+ Q L + Q+A + +K + L + + +T Q SLE +
Sbjct: 1986 EKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQ 2045
Query: 284 EIQGLKENLQNTNA-LNSQTQAFIKSSFD-------------NTSAEIQFL---RG---- 322
+ K L+N A LN + + +K S N S ++ +G
Sbjct: 2046 ALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFAL 2105
Query: 323 HLERAGDEIHVLKRDLKMVTAQTQKAN-------GRLDQTDTQIQVFKSEMEN------V 369
L +E+H L+R ++ + + + +L + + + K ++EN +
Sbjct: 2106 RLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQM 2165
Query: 370 NTLNAQIQVLNGHMKNASREIQTLKQGMKNASALTSQTQMLDSNLQKASAEIQRLRGDLE 429
+ N ++ +L+ +N+ E++TLK +Q + + +L+ ++ LR + E
Sbjct: 2166 SEENQELVILDA--ENSKAEVETLK----------TQIEEMARSLKVFELDLVTLRSEKE 2213
Query: 430 NTKALTMEIQQEQSRLKTLHVVITSQEQLQRTQSQ 464
N LT +IQ++Q +L L +++S + L + Q
Sbjct: 2214 N---LTKQIQEKQGQLSELDKLLSSFKSLLEEKEQ 2245
Score = 40.8 bits (94), Expect = 0.004
Identities = 75/386 (19%), Positives = 161/386 (41%), Gaps = 46/386 (11%)
Query: 101 RELIQTFKGHMENSSAWVVEIQMLKCRVDNVNSQLQVLGDHLGNTNADIQMVKGVLKDAT 160
+E +Q+ H+E ++ Q +K N +++ L N + +I+ + VL D+
Sbjct: 637 KENLQSKINHLETC----LKTQQIKSH--EYNERVRTLEMDRENLSVEIRNLHNVL-DSK 689
Query: 161 TLSLQTQMLRSSLEGTNAEI--QRLKEDLEKADALTFQTLNFLKSSLENTSIELHVLSRG 218
++ ++TQ L AE Q+ ++++E T Q L +E+ +L +LS
Sbjct: 690 SVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQ----LTGQVEDLEHKLQLLSNE 745
Query: 219 LENANSEIQMLNASLETANTQAQLANSSL-KNANAEIYVLR---------------GHLD 262
+ + + Q L+A E+ + ++SL N + + +L G
Sbjct: 746 IMDKDRCYQDLHAEYESLRDLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANIIGEQG 805
Query: 263 SVNDLRTQNQVLRNSLEGANAEIQGLKENLQNTNALNSQTQAFIKSSFDNTSAEIQFLRG 322
S+ R++ ++ + +A +Q ++L+ + L SQ Q + S E+ ++G
Sbjct: 806 SMPSERSECRLEADQSPKNSAILQNRVDSLEFS--LESQKQ--MNSDLQKQCEELVQIKG 861
Query: 323 HLER---AGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQVFKSEMENVNTLNAQIQVL 379
+E +++H V +Q+ + + T V + + ++Q+L
Sbjct: 862 EIEENLMKAEQMHQ-----SFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLL 916
Query: 380 NGHMKNASREIQTLKQGMKNASALTSQTQMLDSNLQKASAEIQRLRGDLENTKALTMEIQ 439
N ++ EIQ LK+ + Q+L L S E + + + K E+
Sbjct: 917 NDKVETEQAEIQELKKSNHLLEDSLKELQLLSETL---SLEKKEMSSIISLNKREIEELT 973
Query: 440 QEQSRLKTLHVVITSQEQ--LQRTQS 463
QE LK ++ + ++ +Q+++S
Sbjct: 974 QENGTLKEINASLNQEKMNLIQKSES 999
Score = 40.0 bits (92), Expect = 0.006
Identities = 85/413 (20%), Positives = 159/413 (38%), Gaps = 38/413 (9%)
Query: 120 EIQMLKCRVDNVNSQLQVLGDHLGNTNADIQMVKGVLK----DATTLSLQTQMLRSSLEG 175
+IQ L+ ++D + + Q L + A +Q K ++ + T L + Q L E
Sbjct: 19 KIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEICES 78
Query: 176 TNAEIQRLKEDLE-KADALTFQ--TLNFLKSSLENTSIELHVLSRGLENANSEIQMLNAS 232
Q++ +L+ K + FQ LN K +E EL LE + Q + S
Sbjct: 79 LEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSADVS 138
Query: 233 LETANTQAQLANSSLKNANAEIYVLRGHLDSVNDLRTQNQVLRNSLEGANAEIQGLKENL 292
L NT ++ + L + Y + + + + R LE +Q K +
Sbjct: 139 LNPCNTPQKIFTTPLTPSQ---YYSGSKYEDLKEKYNKEVEERKRLEAEVKALQAKKASQ 195
Query: 293 QNTNA-LNSQTQAFIKSSFDNTSAEIQFLRGHLERAGDEIHVLKRDLKMVTAQTQKANGR 351
A +N + A ++S S + + HL + + ++RD +A
Sbjct: 196 TLPQATMNHRDIARHQASSSVFSWQQEKTPSHLS-SNSQRTPIRRDF---SASYFSGEQE 251
Query: 352 LDQTDTQIQVFK-----SEMENVNT--LNAQIQVLNGHMKNASREIQTLKQG-MKNASAL 403
+ + + +Q+ K S +N ++ L Q++ N ++N E++ QG K
Sbjct: 252 VTPSRSTLQIGKRDANSSFFDNSSSPHLLDQLKAQNQELRNKINELELRLQGHEKEMKGQ 311
Query: 404 TSQTQMLDSNLQKASAE-------IQRLRGDLENT-----KALTMEIQQEQSRLKTLHVV 451
++ Q L L+KA E + + R +L T +A T EQ K +
Sbjct: 312 VNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDL 371
Query: 452 ITSQEQLQRTQSQLLQMVLQGWKFNGGSLYYFSSVKKSWHEAEQFCVSQGAHL 504
++ + + L Q + + K L S ++S+ +Q C+ A L
Sbjct: 372 SCQRQNAESARCSLEQKIKEKEKEFQEEL---SRQQRSFQTLDQECIQMKARL 421
Score = 39.7 bits (91), Expect = 0.008
Identities = 63/335 (18%), Positives = 129/335 (38%), Gaps = 23/335 (6%)
Query: 140 DHLGNTNADI-QMVKGVLKDATTLSLQTQMLRSSLEGTNAEIQRLKEDLEKADALTFQTL 198
+ GN D+ Q K + + L S E E+++LKE K L
Sbjct: 1030 EETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQEFLTKL 1089
Query: 199 NFLKSSLENTSIELHVLSRGLENANSEIQMLNASLETANTQAQLANSSLKNANAEIYVLR 258
F + +N +EL + + L + ++ Q N+ E + ++ +LK ++
Sbjct: 1090 AFAEERNQNLMLELETVQQALRSEMTDNQN-NSKSEAGGLKQEI--MTLKEEQNKMQ--- 1143
Query: 259 GHLDSVNDLRTQNQ----VLRNSLEGANAEIQGLKENLQNTNALNSQTQAFIKSSFDNTS 314
VNDL +N+ V++ E N E + ++ +++ + + Q K D
Sbjct: 1144 ---KEVNDLLQENEQLMKVMKTKHECQNLESEPIRNSVKERE--SERNQCNFKPQMDLEV 1198
Query: 315 AEIQFLRGHLERAGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQVFKSEMENVNTLNA 374
EI + + E + ++LK+ ++ +K + ++Q + ++E N +
Sbjct: 1199 KEISLDSYNAQLVQLEAMLRNKELKLQESEKEK-----ECLQHELQTIRGDLETSNLQDM 1253
Query: 375 QIQVLNGHMKNASREIQTLKQGMKNASALTSQTQMLDSNLQKASAEIQRLRGDLENTKAL 434
Q Q ++G + G S + L +LQ ++ L E +A
Sbjct: 1254 QSQEISGLKDCEIDAEEKYISGPHELSTSQNDNAHLQCSLQTTMNKLNELEKICEILQAE 1313
Query: 435 TMEIQQEQSRLKTLHVVITSQEQLQRTQSQLLQMV 469
E+ E + ++ IT+ ++ +LL V
Sbjct: 1314 KYELVTELNDSRS--ECITATRKMAEEVGKLLNEV 1346
Score = 36.6 bits (83), Expect = 0.066
Identities = 64/357 (17%), Positives = 132/357 (36%), Gaps = 61/357 (17%)
Query: 170 RSSLEGTNAEIQRLKEDLEKADALTFQTLNFLKSSLENTSIELHVLSRGLENANSEIQML 229
+SS E + ++ + ++ L+ ++S + E L LE +E L
Sbjct: 1876 KSSREDIGDNVAKVNDSWKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCL 1935
Query: 230 NASLETANTQAQLANSSLKNANAEIYVLRGHLDSVNDLRTQNQVLRNSLEGANAEIQG-- 287
E L +E LRG LD+++ T L ++ E++
Sbjct: 1936 EKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQ 1995
Query: 288 -------------LKENLQNTNALNSQTQAFIK---------SSFDNTSAEIQFLRGHLE 325
+KE + L+S +K S + S + + LE
Sbjct: 1996 SECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELE 2055
Query: 326 RAGDEIHVLKRDLKMVTAQTQKANGRLDQTD-TQIQVFK-----------------SEME 367
++I L ++ +++ +++ RL ++D ++ V K S E
Sbjct: 2056 ---NQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQE 2112
Query: 368 NVNTLNAQIQVLNGHMKNASRE----IQTLKQGMKNASALTSQTQMLDSNLQKASAEIQR 423
V+ L I+ L ++ ++ + LK+ + +L + + L+ LQ + +
Sbjct: 2113 EVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQEL 2172
Query: 424 LRGDLENTKA----LTMEIQQEQSRLKTLHVVITS--------QEQLQRTQSQLLQM 468
+ D EN+KA L +I++ LK + + + +Q+Q Q QL ++
Sbjct: 2173 VILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSEL 2229
Score = 35.8 bits (81), Expect = 0.11
Identities = 26/126 (20%), Positives = 55/126 (43%), Gaps = 4/126 (3%)
Query: 326 RAGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQVFKSEMENVNTLNAQIQVLNGHMKN 385
RA +I L+ L + + Q+ +LD + +Q K ++EN T ++ N +
Sbjct: 15 RALQKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLME 74
Query: 386 ASREIQTLKQGMKN-ASALTSQTQMLDSNLQKASAEIQRLRGDLENTKALTMEIQQEQSR 444
++ KQ + + SQ + L +I++L +L+ K+ E+++ Q
Sbjct: 75 ICESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKS---ELERSQQA 131
Query: 445 LKTLHV 450
++ V
Sbjct: 132 AQSADV 137
Score = 31.2 bits (69), Expect = 2.8
Identities = 57/304 (18%), Positives = 124/304 (40%), Gaps = 39/304 (12%)
Query: 96 REAEMRELIQTF-KGHMENSSAWVVEIQMLKCRVDNVNSQLQVLGDHL-----GNTNADI 149
R+ E+ +L + F K H E ++ ++ + R N+ +L+ + L N N
Sbjct: 1067 RKNELEQLKEAFAKEHQE----FLTKLAFAEERNQNLMLELETVQQALRSEMTDNQNNSK 1122
Query: 150 QMVKGVLKDATTLSLQTQMLRSSLEGTNAEIQRLKEDLE-KADALTFQTLNFLKSSLENT 208
G+ ++ TL + ++ + E ++L + ++ K + ++ S E
Sbjct: 1123 SEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHECQNLESEPIRNSVKERE 1182
Query: 209 S----------IELHVLSRGLENANSEIQMLNASLETANTQAQLANSSLKNANAEIYVLR 258
S ++L V L++ N+++ L A L + Q + + E+ +R
Sbjct: 1183 SERNQCNFKPQMDLEVKEISLDSYNAQLVQLEAMLRNKELKLQESEKEKECLQHELQTIR 1242
Query: 259 GHLDSVNDLRTQNQVLRNSLEGANAEIQGLKE-NLQNTNALNSQTQAFIKSSFDNTSAEI 317
G L++ N Q+Q EI GLK+ + S S DN
Sbjct: 1243 GDLETSNLQDMQSQ-----------EISGLKDCEIDAEEKYISGPHELSTSQNDNA---- 1287
Query: 318 QFLRGHLERAGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQ-IQVFKSEMENVNTLNAQI 376
L+ L+ ++++ L++ +++ A+ + L+ + ++ I + E V L ++
Sbjct: 1288 -HLQCSLQTTMNKLNELEKICEILQAEKYELVTELNDSRSECITATRKMAEEVGKLLNEV 1346
Query: 377 QVLN 380
++LN
Sbjct: 1347 KILN 1350
>gi|4502251 asialoglycoprotein receptor 1 [Homo sapiens]
Length = 291
Score = 68.2 bits (165), Expect = 2e-11
Identities = 47/178 (26%), Positives = 87/178 (48%), Gaps = 15/178 (8%)
Query: 378 VLNGHMKNASREIQTLKQGMKNASA--------LTSQTQMLDSNLQKASAEIQRLRGDL- 428
V+ E++ L++ N +A L++Q + ++ +++++ + DL
Sbjct: 58 VIGSQNSQLQEELRGLRETFSNFTASTEAQVKGLSTQGGNVGRKMKSLESQLEKQQKDLS 117
Query: 429 ENTKALTMEIQQEQSRLKTLHVVITSQEQLQRTQSQLLQMVLQGWKFNGGSLYYFSSVKK 488
E+ +L + ++Q S L++L + + LQ S+ + W + S Y+FS K
Sbjct: 118 EDHSSLLLHVKQFVSDLRSLSCQMAA---LQGNGSERTCCPVN-WVEHERSCYWFSRSGK 173
Query: 489 SWHEAEQFCVSQGAHLASVASKEEQAFLVEFTSKVYYWIGLTDRGTEGSWRWTDGTPF 546
+W +A+ +C + AHL V S EEQ F+ V W+GL D+ G W+W DGT +
Sbjct: 174 AWADADNYCRLEDAHLVVVTSWEEQKFVQHHIGPVNTWMGLHDQ--NGPWKWVDGTDY 229
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 67.8 bits (164), Expect = 3e-11
Identities = 70/338 (20%), Positives = 138/338 (40%), Gaps = 15/338 (4%)
Query: 129 DNVNSQLQVLGDHLGNTNADIQMVKGVLKDATTLSLQTQMLRSSLEGTNAEIQRLKEDLE 188
D + Q+Q L + L +T A+ V L+D Q Q +S EG ++ +L
Sbjct: 1260 DVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELH 1319
Query: 189 KADALTFQTLNFLKSSLENTSIELHVLSRGLENANSEIQMLNASLETANTQAQLANSSLK 248
+ A L + E +L EN ++++ L A++ A QA A +
Sbjct: 1320 ETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEE 1379
Query: 249 NANAEIYVLRGHLDSVNDLRTQNQVLRNSLEGANAEIQGLKENLQNTNALNSQTQAFIKS 308
+ L+ + V R + Q L+ E A+ + L+ENL AL +QT A
Sbjct: 1380 DLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENL----ALLTQTLA---- 1431
Query: 309 SFDNTSAEIQFLRGHLERAGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQVFKSEMEN 368
E++ LRG ++ + + K L++++ +K N +D QIQ +
Sbjct: 1432 ---EREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSV 1488
Query: 369 VNTLNAQIQVLNGHMKNASREIQTLKQGMKNASALTS----QTQMLDSNLQKASAEIQRL 424
+ L +Q + +I+ L++ + + + + D ++ ++Q L
Sbjct: 1489 LEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDL 1548
Query: 425 RGDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQRTQ 462
+ L + L +E+++ +++ +I E + TQ
Sbjct: 1549 KKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQ 1586
Score = 45.8 bits (107), Expect = 1e-04
Identities = 56/343 (16%), Positives = 142/343 (41%), Gaps = 17/343 (4%)
Query: 131 VNSQLQVLGDHLGNTNADIQMVKGVLKDATTLSLQTQMLRSSLEGTNAEIQRLKEDLEKA 190
+ L +L L +++ ++G +++ L Q +M +++LE + ++++ ++++
Sbjct: 1419 LQENLALLTQTLAEREEEVETLRGQIQE---LEKQREMQKAALELLSLDLKKRNQEVDLQ 1475
Query: 191 DALTFQTLNFLKSSLENTSIELHVLSRGLENANSEIQMLNASLETANTQAQLANSSLKNA 250
Q L +S LE+ + + + L +I+ L ET + L+
Sbjct: 1476 QE-QIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKK 1534
Query: 251 NAEIYVLRGHLDSVNDLRTQNQVLRNSLEGANAEI---QGLKENLQNTNALNSQTQAFIK 307
+ I RG + + + L LE + ++ Q L + L+ +
Sbjct: 1535 DQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLT 1594
Query: 308 SSFDNTSAEIQFLRGHLERAGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQVFKSEME 367
+ S E+Q + VL R+L+ + + ++++ Q + ++E
Sbjct: 1595 LDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLE 1654
Query: 368 N----VNTLNAQIQVLNGHMKNASR----EIQTLKQGMKNASA-LTSQTQMLDSNLQKAS 418
+ +IQVL ++ +++ +K ++ LT+Q Q++ ++
Sbjct: 1655 RRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGK 1714
Query: 419 AEIQRLRGDLENTKALTMEIQQE-QSRLKTLHVVITSQEQLQR 460
+ RG LE+ K + + ++E + + + +H + ++QL++
Sbjct: 1715 GPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQ 1757
Score = 43.5 bits (101), Expect = 5e-04
Identities = 75/316 (23%), Positives = 129/316 (40%), Gaps = 46/316 (14%)
Query: 181 QRLKEDLEKADALTFQTLNFLKSSLENTSIELHVLSRGLENANSEIQMLNAS---LETAN 237
QRL++ + D L QT++ L+ +++ S E +L + E ++++L L N
Sbjct: 435 QRLQKLTGERDTLAGQTVD-LQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVN 493
Query: 238 TQAQLANSSLKNANAEIY---------------VLRGHLDSVNDLRTQNQVLRNSLEGAN 282
+ QL S + E +L G ++ ++ LR +LE ++
Sbjct: 494 VELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESSH 553
Query: 283 AEIQGLK-ENLQNTNALNSQTQAFIK-SSFDNT-SAEIQFLRGHLERAGDEIHVLKRDLK 339
E + L+ E + T AL Q+ + SS +NT E+ LR A ++ L L
Sbjct: 554 LEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRA----AAVKLSALNEALA 609
Query: 340 MVTAQTQKANGRLDQTDTQIQVFKSEMENVNTLNAQIQVLNGHMKNASREIQTLKQGMKN 399
+ N +L Q + + Q S ME +QV L + K
Sbjct: 610 L---DKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQV-------------DLAEAEKR 653
Query: 400 ASALTSQTQMLDSNLQKASAEIQRLRGDLENTKALTMEIQQEQSRLKTLHVVITSQ-EQL 458
AL + L++ LQKA L+ DL + + EIQ++ S + T+Q EQL
Sbjct: 654 REALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQL 713
Query: 459 Q---RTQSQLLQMVLQ 471
+ Q ++L +Q
Sbjct: 714 HQEAKRQEEVLARAVQ 729
Score = 41.2 bits (95), Expect = 0.003
Identities = 79/394 (20%), Positives = 153/394 (38%), Gaps = 42/394 (10%)
Query: 95 GREAEMRELIQTFKGHMENSSAWVVEIQMLKCRVDNVNSQLQVLGDHLGNTNADIQMVKG 154
G+E ++E +G +E + + E + + Q + L + L +Q ++
Sbjct: 1831 GQEERVKEKADALQGALEQAHMTLKERHG---ELQDHKEQARRLEEELAVEGRRVQALEE 1887
Query: 155 VLKDATTLSLQTQMLRSSLEGTNAEIQRLKEDLEKADALTFQTLNFLKSSLENTSIELHV 214
VL D S + + +L+ AE + E +A L+ S L
Sbjct: 1888 VLGDLRAESREQEKALLALQQQCAEQAQEHEVETRA----------LQDSWLQAQAVLKE 1937
Query: 215 LSRGLENANSEIQMLNASLETANTQAQLANSSLKNANAEIYVLRGHL----DSVNDLRTQ 270
+ LE +E Q E A +A+ +L A+A + HL + L
Sbjct: 1938 RDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEAS 1997
Query: 271 NQVLRNSLEGANAEIQGLKENLQNTNALNSQTQAFIKSSFDNTSAEIQFLRGHLERAGDE 330
L+ SL+ A + L+E AL Q + I+ ++Q L+ L + +E
Sbjct: 1998 TATLQASLDACQAHSRQLEE------ALRIQ-EGEIQDQDLRYQEDVQQLQQALAQRDEE 2050
Query: 331 I-HVLKRDLKMVTAQTQKANGRLDQTDTQIQVFKSEMENVNTLNAQIQVLNGHMKNASRE 389
+ H +R+ + + Q+ + Q + + E E + L+ ++ L + +E
Sbjct: 2051 LRHQQEREQLLEKSLAQRVQENMIQEKQNLGQEREE-EEIRGLHQSVRELQLTLAQKEQE 2109
Query: 390 IQTLKQGMKN-----------ASALTSQTQMLDSNLQKASAEIQRLRGDLENTKALTMEI 438
I L++ + S + Q+ LDS + E++RL+ L T+A +E
Sbjct: 2110 ILELRETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEAREIEW 2169
Query: 439 QQEQSRL-----KTLHVVITSQEQLQRTQSQLLQ 467
+++ L +T V + QE Q+ +L+
Sbjct: 2170 REKAQDLALSLAQTKASVSSLQEVAMFLQASVLE 2203
Score = 38.1 bits (87), Expect = 0.023
Identities = 70/351 (19%), Positives = 129/351 (36%), Gaps = 27/351 (7%)
Query: 154 GVLKDATTLSLQTQMLRSSLEGTNAEIQRLKEDL---EKADALTFQTLNFLKSSLENTSI 210
G+ + L + Q + S +E L+ DL EK ++ L++ L+
Sbjct: 614 GLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEE 673
Query: 211 ELHVLSRGLENANSEIQMLNASLETANTQAQLANSSLKNANAEIY----VLRGHLDSVND 266
L L + E + + L + Q + A + L+ + E VL +
Sbjct: 674 AGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEA 733
Query: 267 LRTQNQVLRNSLEGANAEIQGLKENLQNTNALNSQTQAFIKSSFDNTSAEIQFLRGHLER 326
L + L L+ + Q L E LQ ++ ++ + + S I+ +G LE
Sbjct: 734 LVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSV-IEVTKGQLEV 792
Query: 327 AGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQVFKSEMENVNTLNAQIQVLNGHMKNA 386
++ VT + G + ++ +S+ E A+ + A
Sbjct: 793 ----------QIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAAR------QLAQA 836
Query: 387 SREIQTLKQGMKNASALTSQTQMLDSNLQKASAEIQRLRGDLENTKALTMEIQQEQSRLK 446
+E +T + K A Q+ + ++ S Q L LE+ + ME++ +
Sbjct: 837 EQEGKTALEQQKAAHE-KEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQ 895
Query: 447 TLHVVITSQEQLQRTQ--SQLLQMVLQGWKFNGGSLYYFSSVKKSWHEAEQ 495
T I +Q + +RTQ S L QM L+ K L +K +A Q
Sbjct: 896 TEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQ 946
Score = 37.4 bits (85), Expect = 0.039
Identities = 66/310 (21%), Positives = 120/310 (38%), Gaps = 64/310 (20%)
Query: 157 KDATTLSLQTQMLRSSLEGTNAEIQRLKEDLEKADALTFQTLNFLKSSLENTSIELHVLS 216
++ L ++Q R E A + L+E L KA A E +E LS
Sbjct: 1940 QELEALRAESQSSRHQEEAARARAEALQEALGKAHAAL--------QGKEQHLLEQAELS 1991
Query: 217 RGLENANSEIQMLNASLETANTQAQLANSSLKNANAEIYVLRGHLDSVNDLRTQNQV--L 274
R LE + + +Q ASL+ ++ +L+ EI DLR Q V L
Sbjct: 1992 RSLEASTATLQ---ASLDACQAHSRQLEEALRIQEGEI--------QDQDLRYQEDVQQL 2040
Query: 275 RNSLEGANAEIQGLKEN---LQNTNALNSQTQAFIKSSFDNTSAEIQFLRGHLERAGDEI 331
+ +L + E++ +E L+ + A Q + E + +RG +
Sbjct: 2041 QQALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRG--------L 2092
Query: 332 HVLKRDLKMVTAQ----------TQKANG------------------RLDQTDTQIQVFK 363
H R+L++ AQ TQ+ N +LD + ++Q
Sbjct: 2093 HQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQ--- 2149
Query: 364 SEMENVNTLNAQIQVLNGHMKNASREIQ-TLKQGMKNASALTSQTQMLDSNLQKASAEIQ 422
E+E + Q + + ++++ +L Q + S+L L +++ + +E Q
Sbjct: 2150 RELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSEQQ 2209
Query: 423 RLRGDLENTK 432
RL+ +LE T+
Sbjct: 2210 RLQDELELTR 2219
>gi|55742774 dectin-2 [Homo sapiens]
Length = 209
Score = 67.0 bits (162), Expect = 5e-11
Identities = 30/75 (40%), Positives = 47/75 (62%), Gaps = 1/75 (1%)
Query: 473 WKFNGGSLYYFSSVKKSWHEAEQFCVSQGAHLASVASKEEQAFLVEFTSKVY-YWIGLTD 531
WK G S Y+ SS +K W ++EQ CV GAHL ++ EQ F+V+ ++ + Y++GL+D
Sbjct: 83 WKSFGSSCYFISSEEKVWSKSEQNCVEMGAHLVVFNTEAEQNFIVQQLNESFSYFLGLSD 142
Query: 532 RGTEGSWRWTDGTPF 546
+W+W D TP+
Sbjct: 143 PQGNNNWQWIDKTPY 157
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 65.9 bits (159), Expect = 1e-10
Identities = 91/402 (22%), Positives = 171/402 (42%), Gaps = 39/402 (9%)
Query: 96 REAEMRELIQTFKGHMENSSAWVVEIQMLKCRVDNVNSQLQVLGDHLGNTNADIQMVKGV 155
R +E+ E Q GH N + ++LK ++N Q L + + V+G
Sbjct: 438 RTSELSEAPQKSLGHEVNE---LTSSRLLKLEMEN-----QSLTKTVEELRTTVDSVEGN 489
Query: 156 LKDATTLSLQTQMLRSSLEGTNAEIQRLKEDLEKADALTFQTLNFLKSSLENTSIELHVL 215
+ + Q L +E EI + K+ L+ L+ + L K+ LE T L
Sbjct: 490 ASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLS-KDLMKEKAQLEKTIETLREN 548
Query: 216 S-RGLENANSEIQMLNASLETANTQAQL-ANSSLKNANAEIYVLRGHL----DSVNDLRT 269
S R ++ E + LN ++ + ++Q+ A + +K+ E +L + ++ +
Sbjct: 549 SERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEF 608
Query: 270 QNQVLRNSLE-----GANAE-IQGLKENLQNTNALNSQTQAFIKSSFDNTSAEIQFLRGH 323
+ + ++ LE G AE ++ +L+ N L + +K + + A ++
Sbjct: 609 EKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA-LEQENSE 667
Query: 324 LERAGDEIHVLKRDLKMVTAQTQ---KANGRLDQTDTQIQVFKSEMENVNTLNAQIQVLN 380
LER ++ K +T Q + K N +LD+ + +++ ++ + AQ+Q+ N
Sbjct: 668 LERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLEN 727
Query: 381 GHMKNASREIQTLKQGMKNASALTSQTQMLDSNLQKASAEIQRLRGDLENT--------- 431
K E + LK+G++ A +T+ L+ + Q E QRL+ LEN+
Sbjct: 728 ---KELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLES 784
Query: 432 --KALTMEIQQEQSRLKTLHVVITSQEQLQRTQSQLLQMVLQ 471
+ L ME Q Q L+ L + EQL++ L Q Q
Sbjct: 785 ELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQ 826
Score = 65.5 bits (158), Expect = 1e-10
Identities = 70/367 (19%), Positives = 160/367 (43%), Gaps = 27/367 (7%)
Query: 119 VEIQMLKCRVDNVNSQLQVLGDHLGNTNADIQMVKGVLKDATTLSLQTQMLRS---SLEG 175
+E Q L+ ++N N ++Q L L + + Q ++ L++ S + + L SLE
Sbjct: 763 IENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQ 822
Query: 176 TNAEIQRLKEDLEKADALTFQTLNFLKSSLENTSIELHVLSRGLENANSEIQMLNASLET 235
+++++ K+ LEK + Q ++LE ++++ L + + + EI + S
Sbjct: 823 ETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVR 882
Query: 236 ANTQAQLANSSLKNANAEIYVLRGHLDSVNDLRTQNQVLRNSLEGANAEIQGL---KENL 292
+ +K A +I L + + + + Q + N LE E++ + KE L
Sbjct: 883 LKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERL 942
Query: 293 ----QNTN-----ALNSQTQAFIKSSFDNTSAEIQFLRGHLERAGDEIHVLKRDLKMVTA 343
Q+T+ L S+ ++ +K S + +I L LE + + L+++LK V
Sbjct: 943 LHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKK 1002
Query: 344 QTQKANGRLDQTDTQIQVFKSEMENVNTLNAQIQVLNGHMKNASREIQTLKQGM----KN 399
+ R D+ + +++ ++ + + +RE+ +K + +N
Sbjct: 1003 NYEALKQRQDE--------ERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERN 1054
Query: 400 ASALTSQTQMLDSNLQKASAEIQRLRGDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQ 459
+ L ++ Q L + L++ + L+ + + T+ +Q++ + L+T + + +
Sbjct: 1055 NATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTL 1114
Query: 460 RTQSQLL 466
+QS L
Sbjct: 1115 NSQSTSL 1121
Score = 54.7 bits (130), Expect = 2e-07
Identities = 69/322 (21%), Positives = 149/322 (46%), Gaps = 28/322 (8%)
Query: 129 DNVNSQLQVL---GDHLGNTNADIQMVKGVLKDATTLSLQTQ--MLRSSLEGTNAEIQRL 183
+N Q+++L +HL T + ++ + +A ++ + +L S++ T++++ ++
Sbjct: 547 ENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKI 606
Query: 184 KEDLE--KADALTFQTLNFLKSSLENTSIELHVLSRGLENANSEIQMLNASLETANTQAQ 241
+ + K + ++ LEN ELH L + E +I L + E Q
Sbjct: 607 EFEKRQIKKELEHYKEKGERAEELEN---ELHHLEKENELLQKKITNLKITCEKIEALEQ 663
Query: 242 LANSSLKNANAEIYVLRGHLDSVNDLRTQNQVLR---NSLEGANAEIQGLKENLQNTNAL 298
NS L+ N + L+ LDS +L Q + L + L+ N E++ E+L+ +
Sbjct: 664 -ENSELERENRK---LKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMK 719
Query: 299 NSQTQAF---IKSSFDNTSAEIQFLRGHLERAGDEIHVLKRDLKMVTAQTQKANGRLDQT 355
+Q Q ++S + ++ L+ ++ + + V + L + + QK L+ +
Sbjct: 720 MAQLQLENKELESEKEQLKKGLELLKASFKKT-ERLEVSYQGLDIENQRLQKT---LENS 775
Query: 356 DTQIQVFKSEMENVNTLNAQIQVLNGHMKNASREIQTLKQGMKNASALTSQTQMLDSNLQ 415
+ +IQ +SE++++ N +Q +K +S+ ++ L+ K +L +T L+ + +
Sbjct: 776 NKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLE---KENKSLEQETSQLEKDKK 832
Query: 416 KASAEIQRLRGDLENTKALTME 437
+ E +RLR E K T+E
Sbjct: 833 QLEKENKRLRQQAE-IKDTTLE 853
Score = 53.1 bits (126), Expect = 7e-07
Identities = 73/320 (22%), Positives = 139/320 (43%), Gaps = 52/320 (16%)
Query: 157 KDATTLSLQTQMLRSSLEGTNAEIQRLKEDLEKADALTFQTLNFLKSSLENTSIELHVLS 216
K T L + + + + LE N+E++R L+K +F+ L F SLE + +L
Sbjct: 646 KKITNLKITCEKIEA-LEQENSELERENRKLKKT-LDSFKNLTFQLESLEKENSQL---- 699
Query: 217 RGLENANSEIQMLNASLETAN---TQAQLANSSLKNANAEIYVLRGHLDSVNDLRTQNQV 273
+ N E++ SL+ A+ Q QL N L++ + L+ L+ + + +
Sbjct: 700 ---DEENLELRRNVESLKCASMKMAQLQLENKELESEKEQ---LKKGLELLKASFKKTER 753
Query: 274 LRNSLEGANAEIQGLKENLQNTNALNSQTQAFIKSSFDNTSAEIQFLRGHLERAGDEIHV 333
L S +G + E Q L++ L+N+N Q ++S + E Q L+ +LE E+ +
Sbjct: 754 LEVSYQGLDIENQRLQKTLENSNKKIQQ----LESELQDLEMENQTLQKNLE----ELKI 805
Query: 334 LKRDLKMVTAQTQKANGRLDQTDTQIQVFKSEMENVNTLNAQIQVLNGHMKNASREIQTL 393
+ L+ Q +K N L+Q +Q++ K ++E N Q +K+ + E +
Sbjct: 806 SSKRLE----QLEKENKSLEQETSQLEKDKKQLEKENKRLRQ----QAEIKDTTLEENNV 857
Query: 394 KQGMKNASALTSQTQMLDSNLQKASAEIQRLRGDLENTKALTMEIQQEQSRLK-----TL 448
K G NL+K + + + G + + E+++E L +
Sbjct: 858 KIG----------------NLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDI 901
Query: 449 HVVITSQEQLQRTQSQLLQM 468
++T +E L + + QM
Sbjct: 902 KTLVTLREDLVSEKLKTQQM 921
Score = 46.6 bits (109), Expect = 6e-05
Identities = 71/326 (21%), Positives = 130/326 (39%), Gaps = 48/326 (14%)
Query: 155 VLKDATTLSLQTQMLRSSLEGTNAEIQRLKEDLEKADALTFQTLNFLKSSLENTSIELHV 214
V ++ TL + Q L++ L+ + L+ + AL QT+ SL+ + L
Sbjct: 1051 VERNNATLQAEKQALKTQLKQLETQNNNLQAQIL---ALQRQTV-----SLQEQNTTLQT 1102
Query: 215 LSRGLENANSEIQMLNASLETANTQAQLANSSLKNANAEIYVLRGHLDSVNDLRTQNQVL 274
+ L+ NS + + SL N Q + SSL+N N + R L S+ D
Sbjct: 1103 QNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYD-------- 1154
Query: 275 RNSLEGANAEIQGLKENLQNTNALNSQTQAFIKSSFDNTSAEIQFLRGHLERAGDEIHVL 334
SL + +++ L E S+ ++ I G L+ A + V
Sbjct: 1155 --SLIKDHEKLELLHERQA------SEYESLISK------------HGTLKSAHKNLEVE 1194
Query: 335 KRDLKMVTAQTQKANGRLDQTDTQIQVFKSEM----ENVNTLNAQIQVLNGHMKNASREI 390
RDL+ Q K G+L+ + ++V + +M +N T+ A+ + L G R
Sbjct: 1195 HRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCG---ENDRLN 1251
Query: 391 QTLKQGMKNASALTSQTQMLDSNLQKASAEIQRLRGDLENTKALTMEIQQEQSRLKTLHV 450
T Q +K L + + L S L + E RL + K ++ ++L
Sbjct: 1252 HTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCE 1311
Query: 451 VITS-----QEQLQRTQSQLLQMVLQ 471
+++ +E+ + Q+ ++LQ
Sbjct: 1312 LLSQLKGNLEEENRHLLDQIQTLMLQ 1337
Score = 46.2 bits (108), Expect = 8e-05
Identities = 79/333 (23%), Positives = 138/333 (41%), Gaps = 39/333 (11%)
Query: 167 QMLRSSLEGTNAEIQRLKEDLEKADALTFQTLNFLKSSLENTSIELHVLSRGLENANSEI 226
Q L L A+I+RL+++LE+ T Q L+ K LE IEL L + N S+
Sbjct: 247 QHLSVELADAKAKIRRLRQELEEK---TEQLLD-CKQELEQMEIELKRLQQENMNLLSDA 302
Query: 227 QM-------LNASLETANTQAQLANSSLKNANAEIYVLRGHLDSVNDLRTQNQV------ 273
+ L+A E A + S + ++ + + V +L+ NQV
Sbjct: 303 RSARMYRDELDALREKA-VRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKT 361
Query: 274 -LRNSLEGANAEIQGL----KENLQNTNALN--SQTQAFIKSSFDNTSAEIQFLRGHLER 326
L + LEG A L KENLQ L+ + + + E L ++
Sbjct: 362 MLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQ 421
Query: 327 AGDEIHVLKRDLKMVTAQT------QKANGRLDQTDTQIQVFKSEMENVNTLNAQIQVLN 380
+ DE L +L+ ++ + QK+ G T ++ K EMEN +L ++ L
Sbjct: 422 SMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMEN-QSLTKTVEELR 480
Query: 381 GHMKNASREIQTLKQGMKNASALTSQTQMLDSNL---QKASAEIQRLRGDLENTKA---L 434
+ + + + K L+ + ++L++ + +++ Q L DL KA
Sbjct: 481 TTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEK 540
Query: 435 TMEIQQEQSRLKTLHVVITSQEQLQRTQSQLLQ 467
T+E +E S + + ++ E L +T S L Q
Sbjct: 541 TIETLRENSE-RQIKILEQENEHLNQTVSSLRQ 572
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 65.9 bits (159), Expect = 1e-10
Identities = 91/402 (22%), Positives = 171/402 (42%), Gaps = 39/402 (9%)
Query: 96 REAEMRELIQTFKGHMENSSAWVVEIQMLKCRVDNVNSQLQVLGDHLGNTNADIQMVKGV 155
R +E+ E Q GH N + ++LK ++N Q L + + V+G
Sbjct: 438 RTSELSEAPQKSLGHEVNE---LTSSRLLKLEMEN-----QSLTKTVEELRTTVDSVEGN 489
Query: 156 LKDATTLSLQTQMLRSSLEGTNAEIQRLKEDLEKADALTFQTLNFLKSSLENTSIELHVL 215
+ + Q L +E EI + K+ L+ L+ + L K+ LE T L
Sbjct: 490 ASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLS-KDLMKEKAQLEKTIETLREN 548
Query: 216 S-RGLENANSEIQMLNASLETANTQAQL-ANSSLKNANAEIYVLRGHL----DSVNDLRT 269
S R ++ E + LN ++ + ++Q+ A + +K+ E +L + ++ +
Sbjct: 549 SERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEF 608
Query: 270 QNQVLRNSLE-----GANAE-IQGLKENLQNTNALNSQTQAFIKSSFDNTSAEIQFLRGH 323
+ + ++ LE G AE ++ +L+ N L + +K + + A ++
Sbjct: 609 EKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA-LEQENSE 667
Query: 324 LERAGDEIHVLKRDLKMVTAQTQ---KANGRLDQTDTQIQVFKSEMENVNTLNAQIQVLN 380
LER ++ K +T Q + K N +LD+ + +++ ++ + AQ+Q+ N
Sbjct: 668 LERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLEN 727
Query: 381 GHMKNASREIQTLKQGMKNASALTSQTQMLDSNLQKASAEIQRLRGDLENT--------- 431
K E + LK+G++ A +T+ L+ + Q E QRL+ LEN+
Sbjct: 728 ---KELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLES 784
Query: 432 --KALTMEIQQEQSRLKTLHVVITSQEQLQRTQSQLLQMVLQ 471
+ L ME Q Q L+ L + EQL++ L Q Q
Sbjct: 785 ELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQ 826
Score = 65.9 bits (159), Expect = 1e-10
Identities = 70/366 (19%), Positives = 160/366 (43%), Gaps = 26/366 (7%)
Query: 119 VEIQMLKCRVDNVNSQLQVLGDHLGNTNADIQMVKGVLKDATTLSLQTQMLRS---SLEG 175
+E Q L+ ++N N ++Q L L + + Q ++ L++ S + + L SLE
Sbjct: 763 IENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQ 822
Query: 176 TNAEIQRLKEDLEKADALTFQTLNFLKSSLENTSIELHVLSRGLENANSEIQMLNASLET 235
+++++ K+ LEK + Q ++LE ++++ L + + + EI + S
Sbjct: 823 ETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVR 882
Query: 236 ANTQAQLANSSLKNANAEIYVLRGHLDSVNDLRTQNQVLRNSLEGANAEIQGL---KENL 292
+ +K A +I L + + + + Q + N LE E++ + KE L
Sbjct: 883 LKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERL 942
Query: 293 ----QNTN----ALNSQTQAFIKSSFDNTSAEIQFLRGHLERAGDEIHVLKRDLKMVTAQ 344
Q+T+ L S+ ++ +K S + +I L LE + + L+++LK V
Sbjct: 943 LHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKN 1002
Query: 345 TQKANGRLDQTDTQIQVFKSEMENVNTLNAQIQVLNGHMKNASREIQTLKQGM----KNA 400
+ R D+ + +++ ++ + + +RE+ +K + +N
Sbjct: 1003 YEALKQRQDE--------ERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNN 1054
Query: 401 SALTSQTQMLDSNLQKASAEIQRLRGDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQR 460
+ L ++ Q L + L++ + L+ + + T+ +Q++ + L+T + + +
Sbjct: 1055 ATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLN 1114
Query: 461 TQSQLL 466
+QS L
Sbjct: 1115 SQSTSL 1120
Score = 54.7 bits (130), Expect = 2e-07
Identities = 69/322 (21%), Positives = 149/322 (46%), Gaps = 28/322 (8%)
Query: 129 DNVNSQLQVL---GDHLGNTNADIQMVKGVLKDATTLSLQTQ--MLRSSLEGTNAEIQRL 183
+N Q+++L +HL T + ++ + +A ++ + +L S++ T++++ ++
Sbjct: 547 ENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKI 606
Query: 184 KEDLE--KADALTFQTLNFLKSSLENTSIELHVLSRGLENANSEIQMLNASLETANTQAQ 241
+ + K + ++ LEN ELH L + E +I L + E Q
Sbjct: 607 EFEKRQIKKELEHYKEKGERAEELEN---ELHHLEKENELLQKKITNLKITCEKIEALEQ 663
Query: 242 LANSSLKNANAEIYVLRGHLDSVNDLRTQNQVLR---NSLEGANAEIQGLKENLQNTNAL 298
NS L+ N + L+ LDS +L Q + L + L+ N E++ E+L+ +
Sbjct: 664 -ENSELERENRK---LKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMK 719
Query: 299 NSQTQAF---IKSSFDNTSAEIQFLRGHLERAGDEIHVLKRDLKMVTAQTQKANGRLDQT 355
+Q Q ++S + ++ L+ ++ + + V + L + + QK L+ +
Sbjct: 720 MAQLQLENKELESEKEQLKKGLELLKASFKKT-ERLEVSYQGLDIENQRLQKT---LENS 775
Query: 356 DTQIQVFKSEMENVNTLNAQIQVLNGHMKNASREIQTLKQGMKNASALTSQTQMLDSNLQ 415
+ +IQ +SE++++ N +Q +K +S+ ++ L+ K +L +T L+ + +
Sbjct: 776 NKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLE---KENKSLEQETSQLEKDKK 832
Query: 416 KASAEIQRLRGDLENTKALTME 437
+ E +RLR E K T+E
Sbjct: 833 QLEKENKRLRQQAE-IKDTTLE 853
Score = 53.1 bits (126), Expect = 7e-07
Identities = 73/320 (22%), Positives = 139/320 (43%), Gaps = 52/320 (16%)
Query: 157 KDATTLSLQTQMLRSSLEGTNAEIQRLKEDLEKADALTFQTLNFLKSSLENTSIELHVLS 216
K T L + + + + LE N+E++R L+K +F+ L F SLE + +L
Sbjct: 646 KKITNLKITCEKIEA-LEQENSELERENRKLKKT-LDSFKNLTFQLESLEKENSQL---- 699
Query: 217 RGLENANSEIQMLNASLETAN---TQAQLANSSLKNANAEIYVLRGHLDSVNDLRTQNQV 273
+ N E++ SL+ A+ Q QL N L++ + L+ L+ + + +
Sbjct: 700 ---DEENLELRRNVESLKCASMKMAQLQLENKELESEKEQ---LKKGLELLKASFKKTER 753
Query: 274 LRNSLEGANAEIQGLKENLQNTNALNSQTQAFIKSSFDNTSAEIQFLRGHLERAGDEIHV 333
L S +G + E Q L++ L+N+N Q ++S + E Q L+ +LE E+ +
Sbjct: 754 LEVSYQGLDIENQRLQKTLENSNKKIQQ----LESELQDLEMENQTLQKNLE----ELKI 805
Query: 334 LKRDLKMVTAQTQKANGRLDQTDTQIQVFKSEMENVNTLNAQIQVLNGHMKNASREIQTL 393
+ L+ Q +K N L+Q +Q++ K ++E N Q +K+ + E +
Sbjct: 806 SSKRLE----QLEKENKSLEQETSQLEKDKKQLEKENKRLRQ----QAEIKDTTLEENNV 857
Query: 394 KQGMKNASALTSQTQMLDSNLQKASAEIQRLRGDLENTKALTMEIQQEQSRLK-----TL 448
K G NL+K + + + G + + E+++E L +
Sbjct: 858 KIG----------------NLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDI 901
Query: 449 HVVITSQEQLQRTQSQLLQM 468
++T +E L + + QM
Sbjct: 902 KTLVTLREDLVSEKLKTQQM 921
Score = 46.6 bits (109), Expect = 6e-05
Identities = 71/326 (21%), Positives = 130/326 (39%), Gaps = 48/326 (14%)
Query: 155 VLKDATTLSLQTQMLRSSLEGTNAEIQRLKEDLEKADALTFQTLNFLKSSLENTSIELHV 214
V ++ TL + Q L++ L+ + L+ + AL QT+ SL+ + L
Sbjct: 1050 VERNNATLQAEKQALKTQLKQLETQNNNLQAQIL---ALQRQTV-----SLQEQNTTLQT 1101
Query: 215 LSRGLENANSEIQMLNASLETANTQAQLANSSLKNANAEIYVLRGHLDSVNDLRTQNQVL 274
+ L+ NS + + SL N Q + SSL+N N + R L S+ D
Sbjct: 1102 QNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYD-------- 1153
Query: 275 RNSLEGANAEIQGLKENLQNTNALNSQTQAFIKSSFDNTSAEIQFLRGHLERAGDEIHVL 334
SL + +++ L E S+ ++ I G L+ A + V
Sbjct: 1154 --SLIKDHEKLELLHERQA------SEYESLISK------------HGTLKSAHKNLEVE 1193
Query: 335 KRDLKMVTAQTQKANGRLDQTDTQIQVFKSEM----ENVNTLNAQIQVLNGHMKNASREI 390
RDL+ Q K G+L+ + ++V + +M +N T+ A+ + L G R
Sbjct: 1194 HRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCG---ENDRLN 1250
Query: 391 QTLKQGMKNASALTSQTQMLDSNLQKASAEIQRLRGDLENTKALTMEIQQEQSRLKTLHV 450
T Q +K L + + L S L + E RL + K ++ ++L
Sbjct: 1251 HTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCE 1310
Query: 451 VITS-----QEQLQRTQSQLLQMVLQ 471
+++ +E+ + Q+ ++LQ
Sbjct: 1311 LLSQLKGNLEEENRHLLDQIQTLMLQ 1336
Score = 46.2 bits (108), Expect = 8e-05
Identities = 79/333 (23%), Positives = 138/333 (41%), Gaps = 39/333 (11%)
Query: 167 QMLRSSLEGTNAEIQRLKEDLEKADALTFQTLNFLKSSLENTSIELHVLSRGLENANSEI 226
Q L L A+I+RL+++LE+ T Q L+ K LE IEL L + N S+
Sbjct: 247 QHLSVELADAKAKIRRLRQELEEK---TEQLLD-CKQELEQMEIELKRLQQENMNLLSDA 302
Query: 227 QM-------LNASLETANTQAQLANSSLKNANAEIYVLRGHLDSVNDLRTQNQV------ 273
+ L+A E A + S + ++ + + V +L+ NQV
Sbjct: 303 RSARMYRDELDALREKA-VRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKT 361
Query: 274 -LRNSLEGANAEIQGL----KENLQNTNALN--SQTQAFIKSSFDNTSAEIQFLRGHLER 326
L + LEG A L KENLQ L+ + + + E L ++
Sbjct: 362 MLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQ 421
Query: 327 AGDEIHVLKRDLKMVTAQT------QKANGRLDQTDTQIQVFKSEMENVNTLNAQIQVLN 380
+ DE L +L+ ++ + QK+ G T ++ K EMEN +L ++ L
Sbjct: 422 SMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMEN-QSLTKTVEELR 480
Query: 381 GHMKNASREIQTLKQGMKNASALTSQTQMLDSNL---QKASAEIQRLRGDLENTKA---L 434
+ + + + K L+ + ++L++ + +++ Q L DL KA
Sbjct: 481 TTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEK 540
Query: 435 TMEIQQEQSRLKTLHVVITSQEQLQRTQSQLLQ 467
T+E +E S + + ++ E L +T S L Q
Sbjct: 541 TIETLRENSE-RQIKILEQENEHLNQTVSSLRQ 572
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.127 0.358
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,798,480
Number of Sequences: 37866
Number of extensions: 754712
Number of successful extensions: 5205
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 161
Number of HSP's successfully gapped in prelim test: 546
Number of HSP's that attempted gapping in prelim test: 3382
Number of HSP's gapped (non-prelim): 1683
length of query: 589
length of database: 18,247,518
effective HSP length: 108
effective length of query: 481
effective length of database: 14,157,990
effective search space: 6809993190
effective search space used: 6809993190
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.