Guide to the Human Genome
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Search of human proteins with 4758786

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4758786 NADH dehydrogenase (ubiquinone) Fe-S protein 2 [Homo
sapiens]
         (463 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4758786 NADH dehydrogenase (ubiquinone) Fe-S protein 2 [Homo ...   955   0.0  
gi|22547149 F-box only protein 22 isoform a [Homo sapiens]             35   0.19 
gi|13443000 F-box only protein 22 isoform b [Homo sapiens]             35   0.19 
gi|210147567 hypothetical protein LOC220081 [Homo sapiens]             33   0.42 
gi|4759328 class I cytokine receptor [Homo sapiens]                    30   3.5  
gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]                 30   4.6  
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]                 30   4.6  
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]                 30   4.6  
gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo...    29   7.9  
gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo...    29   7.9  
gi|16554568 cyclin D-type binding-protein 1 isoform 2 [Homo sapi...    29   7.9  
gi|227500367 cyclin D-type binding-protein 1 isoform 1 [Homo sap...    29   7.9  

>gi|4758786 NADH dehydrogenase (ubiquinone) Fe-S protein 2 [Homo
           sapiens]
          Length = 463

 Score =  955 bits (2468), Expect = 0.0
 Identities = 463/463 (100%), Positives = 463/463 (100%)

Query: 1   MAALRALCGFRGVAAQVLRPGAGVRLPIQPSRGVRQWQPDVEWAQQFGGAVMYPSKETAH 60
           MAALRALCGFRGVAAQVLRPGAGVRLPIQPSRGVRQWQPDVEWAQQFGGAVMYPSKETAH
Sbjct: 1   MAALRALCGFRGVAAQVLRPGAGVRLPIQPSRGVRQWQPDVEWAQQFGGAVMYPSKETAH 60

Query: 61  WKPPPWNDVDPPKDTIVKNITLNFGPQHPAAHGVLRLVMELSGEMVRKCDPHIGLLHRGT 120
           WKPPPWNDVDPPKDTIVKNITLNFGPQHPAAHGVLRLVMELSGEMVRKCDPHIGLLHRGT
Sbjct: 61  WKPPPWNDVDPPKDTIVKNITLNFGPQHPAAHGVLRLVMELSGEMVRKCDPHIGLLHRGT 120

Query: 121 EKLIEYKTYLQALPYFDRLDYVSMMCNEQAYSLAVEKLLNIRPPPRAQWIRVLFGEITRL 180
           EKLIEYKTYLQALPYFDRLDYVSMMCNEQAYSLAVEKLLNIRPPPRAQWIRVLFGEITRL
Sbjct: 121 EKLIEYKTYLQALPYFDRLDYVSMMCNEQAYSLAVEKLLNIRPPPRAQWIRVLFGEITRL 180

Query: 181 LNHIMAVTTHALDLGAMTPFFWLFEEREKMFEFYERVSGARMHAAYIRPGGVHQDLPLGL 240
           LNHIMAVTTHALDLGAMTPFFWLFEEREKMFEFYERVSGARMHAAYIRPGGVHQDLPLGL
Sbjct: 181 LNHIMAVTTHALDLGAMTPFFWLFEEREKMFEFYERVSGARMHAAYIRPGGVHQDLPLGL 240

Query: 241 MDDIYQFSKNFSLRLDELEELLTNNRIWRNRTIDIGVVTAEEALNYGFSGVMLRGSGIQW 300
           MDDIYQFSKNFSLRLDELEELLTNNRIWRNRTIDIGVVTAEEALNYGFSGVMLRGSGIQW
Sbjct: 241 MDDIYQFSKNFSLRLDELEELLTNNRIWRNRTIDIGVVTAEEALNYGFSGVMLRGSGIQW 300

Query: 301 DLRKTQPYDVYDQVEFDVPVGSRGDCYDRYLCRVEEMRQSLRIIAQCLNKMPPGEIKVDD 360
           DLRKTQPYDVYDQVEFDVPVGSRGDCYDRYLCRVEEMRQSLRIIAQCLNKMPPGEIKVDD
Sbjct: 301 DLRKTQPYDVYDQVEFDVPVGSRGDCYDRYLCRVEEMRQSLRIIAQCLNKMPPGEIKVDD 360

Query: 361 AKVSPPKRAEMKTSMESLIHHFKLYTEGYQVPPGATYTAIEAPKGEFGVYLVSDGSSRPY 420
           AKVSPPKRAEMKTSMESLIHHFKLYTEGYQVPPGATYTAIEAPKGEFGVYLVSDGSSRPY
Sbjct: 361 AKVSPPKRAEMKTSMESLIHHFKLYTEGYQVPPGATYTAIEAPKGEFGVYLVSDGSSRPY 420

Query: 421 RCKIKAPGFAHLAGLDKMSKGHMLADVVAIIGTQDIVFGEVDR 463
           RCKIKAPGFAHLAGLDKMSKGHMLADVVAIIGTQDIVFGEVDR
Sbjct: 421 RCKIKAPGFAHLAGLDKMSKGHMLADVVAIIGTQDIVFGEVDR 463


>gi|22547149 F-box only protein 22 isoform a [Homo sapiens]
          Length = 403

 Score = 34.7 bits (78), Expect = 0.19
 Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 8/99 (8%)

Query: 334 VEEMRQSLRIIAQCLNKMPPGEIKVDDAKVSPPKRAEMKTSMESLIHHFKLYTEGYQVPP 393
           V E  +++RI+   +  M   E  +   +    KRA  +TSME+ +   KL+ +  QV  
Sbjct: 88  VAEELENVRILPHTVLYMADSETFISLEECRGHKRARKRTSMETALALEKLFPKQCQVLG 147

Query: 394 GATYTAIEAPKGEFGVYLVSDGSSRPYRCKIKAPGFAHL 432
             T   +  P G         GS+RP   +I   GFA L
Sbjct: 148 IVTPGIVVTPMG--------SGSNRPQEIEIGESGFALL 178


>gi|13443000 F-box only protein 22 isoform b [Homo sapiens]
          Length = 276

 Score = 34.7 bits (78), Expect = 0.19
 Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 8/99 (8%)

Query: 334 VEEMRQSLRIIAQCLNKMPPGEIKVDDAKVSPPKRAEMKTSMESLIHHFKLYTEGYQVPP 393
           V E  +++RI+   +  M   E  +   +    KRA  +TSME+ +   KL+ +  QV  
Sbjct: 88  VAEELENVRILPHTVLYMADSETFISLEECRGHKRARKRTSMETALALEKLFPKQCQVLG 147

Query: 394 GATYTAIEAPKGEFGVYLVSDGSSRPYRCKIKAPGFAHL 432
             T   +  P G         GS+RP   +I   GFA L
Sbjct: 148 IVTPGIVVTPMG--------SGSNRPQEIEIGESGFALL 178


>gi|210147567 hypothetical protein LOC220081 [Homo sapiens]
          Length = 696

 Score = 33.5 bits (75), Expect = 0.42
 Identities = 23/76 (30%), Positives = 36/76 (47%)

Query: 108 KCDPHIGLLHRGTEKLIEYKTYLQALPYFDRLDYVSMMCNEQAYSLAVEKLLNIRPPPRA 167
           K + +I +  R  +K+I   TY Q     +       +  E    +  + +L   P P A
Sbjct: 589 KINEYIQVQIRSQDKIIFCFTYEQKQICLNLGTRYKFVIPEVLSEMKKKTILEAEPGPTA 648

Query: 168 QWIRVLFGEITRLLNH 183
           Q IRVL G++ RLLN+
Sbjct: 649 QKIRVLLGKMNRLLNY 664


>gi|4759328 class I cytokine receptor [Homo sapiens]
          Length = 636

 Score = 30.4 bits (67), Expect = 3.5
 Identities = 17/53 (32%), Positives = 23/53 (43%), Gaps = 6/53 (11%)

Query: 14  AAQVLRPGAGVRLPIQPSRGVRQWQPDVEWAQQFGGAVMYPSKETAHWKPPPW 66
           A Q L P   V L  Q      +  PDV++++        P + T HW PP W
Sbjct: 110 AGQPLWPPVFVNLETQMKPNAPRLGPDVDFSEDD------PLEATVHWAPPTW 156


>gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]
          Length = 548

 Score = 30.0 bits (66), Expect = 4.6
 Identities = 15/46 (32%), Positives = 19/46 (41%), Gaps = 8/46 (17%)

Query: 48  GGAVMYPSKETAHWKPPPWNDVDPPKDTIVKNITLNFGPQHPAAHG 93
           GG   +P +   +  PPPW    PP         +N GP  P  HG
Sbjct: 406 GGHGGHPMQHNPNGPPPPWMQPPPP--------PMNQGPHPPGHHG 443


>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
          Length = 638

 Score = 30.0 bits (66), Expect = 4.6
 Identities = 15/46 (32%), Positives = 19/46 (41%), Gaps = 8/46 (17%)

Query: 48  GGAVMYPSKETAHWKPPPWNDVDPPKDTIVKNITLNFGPQHPAAHG 93
           GG   +P +   +  PPPW    PP         +N GP  P  HG
Sbjct: 406 GGHGGHPMQHNPNGPPPPWMQPPPP--------PMNQGPHPPGHHG 443


>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
          Length = 639

 Score = 30.0 bits (66), Expect = 4.6
 Identities = 15/46 (32%), Positives = 19/46 (41%), Gaps = 8/46 (17%)

Query: 48  GGAVMYPSKETAHWKPPPWNDVDPPKDTIVKNITLNFGPQHPAAHG 93
           GG   +P +   +  PPPW    PP         +N GP  P  HG
Sbjct: 406 GGHGGHPMQHNPNGPPPPWMQPPPP--------PMNQGPHPPGHHG 443


>gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo
            sapiens]
          Length = 1059

 Score = 29.3 bits (64), Expect = 7.9
 Identities = 14/38 (36%), Positives = 18/38 (47%)

Query: 405  GEFGVYLVSDGSSRPYRCKIKAPGFAHLAGLDKMSKGH 442
            G F  +L +    RP+RC     GFA+  GL K    H
Sbjct: 1002 GYFRKHLAAHQGGRPFRCSSCGEGFANTYGLKKHRLAH 1039


>gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo
            sapiens]
          Length = 1059

 Score = 29.3 bits (64), Expect = 7.9
 Identities = 14/38 (36%), Positives = 18/38 (47%)

Query: 405  GEFGVYLVSDGSSRPYRCKIKAPGFAHLAGLDKMSKGH 442
            G F  +L +    RP+RC     GFA+  GL K    H
Sbjct: 1002 GYFRKHLAAHQGGRPFRCSSCGEGFANTYGLKKHRLAH 1039


>gi|16554568 cyclin D-type binding-protein 1 isoform 2 [Homo
           sapiens]
          Length = 232

 Score = 29.3 bits (64), Expect = 7.9
 Identities = 13/43 (30%), Positives = 21/43 (48%)

Query: 152 SLAVEKLLNIRPPPRAQWIRVLFGEITRLLNHIMAVTTHALDL 194
           +L + K  ++ P P   WI +L   I   +N I  +T   L+L
Sbjct: 190 ALEITKASHVTPQPEDSWIPLLINAIDHCMNRIKELTQSELEL 232


>gi|227500367 cyclin D-type binding-protein 1 isoform 1 [Homo
           sapiens]
          Length = 360

 Score = 29.3 bits (64), Expect = 7.9
 Identities = 13/43 (30%), Positives = 21/43 (48%)

Query: 152 SLAVEKLLNIRPPPRAQWIRVLFGEITRLLNHIMAVTTHALDL 194
           +L + K  ++ P P   WI +L   I   +N I  +T   L+L
Sbjct: 318 ALEITKASHVTPQPEDSWIPLLINAIDHCMNRIKELTQSELEL 360


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.139    0.435 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,780,227
Number of Sequences: 37866
Number of extensions: 941558
Number of successful extensions: 2231
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2215
Number of HSP's gapped (non-prelim): 22
length of query: 463
length of database: 18,247,518
effective HSP length: 106
effective length of query: 357
effective length of database: 14,233,722
effective search space: 5081438754
effective search space used: 5081438754
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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