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Search of human proteins with 4758208
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758208 dual specificity phosphatase 3 [Homo sapiens]
(185 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758208 dual specificity phosphatase 3 [Homo sapiens] 371 e-103
gi|56117818 muscle-restricted dual specificity phosphatase isofo... 137 5e-33
gi|51491914 dual specificity phosphatase and pro isomerase domai... 135 3e-32
gi|56237018 testis and skeletal muscle-specific dual specificity... 130 5e-31
gi|56117822 testis and skeletal muscle-specific dual specificity... 130 5e-31
gi|56117820 testis and skeletal muscle-specific dual specificity... 130 5e-31
gi|122937243 dual specificity phosphatase 27 [Homo sapiens] 125 2e-29
gi|13128968 dual specificity phosphatase 26 [Homo sapiens] 124 4e-29
gi|4503421 dual specificity phosphatase 9 [Homo sapiens] 87 8e-18
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens] 87 8e-18
gi|4758206 dual specificity phosphatase 2 [Homo sapiens] 86 2e-17
gi|62865890 dual specificity phosphatase 5 [Homo sapiens] 85 3e-17
gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo sapi... 84 7e-17
gi|4758204 dual specificity phosphatase 1 [Homo sapiens] 84 9e-17
gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens] 84 9e-17
gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens] 84 9e-17
gi|238231453 dual specificity phosphatase 7 [Homo sapiens] 80 8e-16
gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens] 80 1e-15
gi|9910432 dual specificity phosphatase 22 [Homo sapiens] 74 7e-14
gi|38372911 dual specificity phosphatase 16 [Homo sapiens] 74 7e-14
gi|239582767 slingshot homolog 3 [Homo sapiens] 73 2e-13
gi|21536333 dual specificity phosphatase 10 isoform b [Homo sapi... 72 2e-13
gi|21536331 dual specificity phosphatase 10 isoform b [Homo sapi... 72 2e-13
gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo ... 72 3e-13
gi|194733759 serine/threonine/tyrosine interacting protein [Homo... 72 3e-13
gi|21687043 serine/threonine/tyrosine interacting protein [Homo ... 72 3e-13
gi|29826315 dual specificity phosphatase 15 isoform a [Homo sapi... 67 7e-12
gi|153281158 dual specificity phosphatase 8 [Homo sapiens] 65 3e-11
gi|5902002 dual specificity phosphatase 14 [Homo sapiens] 65 3e-11
gi|225703077 dual specificity phosphatase 21 [Homo sapiens] 65 4e-11
>gi|4758208 dual specificity phosphatase 3 [Homo sapiens]
Length = 185
Score = 371 bits (952), Expect = e-103
Identities = 185/185 (100%), Positives = 185/185 (100%)
Query: 1 MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL 60
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
Sbjct: 1 MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL 60
Query: 61 NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV 120
NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
Sbjct: 61 NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV 120
Query: 121 LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE 180
LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
Sbjct: 121 LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE 180
Query: 181 GKLKP 185
GKLKP
Sbjct: 181 GKLKP 185
>gi|56117818 muscle-restricted dual specificity phosphatase isoform
1 [Homo sapiens]
Length = 188
Score = 137 bits (345), Expect = 5e-33
Identities = 77/175 (44%), Positives = 113/175 (64%), Gaps = 7/175 (4%)
Query: 8 SVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRS 67
S+ +L +LL G S +EV P +++G+A+ A + +L KLGITHVLNAA
Sbjct: 20 SILELEELLRAGKSSCSR----VDEVWPNLFIGDAATANNRFELWKLGITHVLNAAH--K 73
Query: 68 FMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREG 127
++ +FY S ++YLG+ A+D +F++SAYF AADFI +AL +VLVHC G
Sbjct: 74 GLYCQGGPDFY-GSSVSYLGVPAHDLPDFDISAYFSSAADFIHRALNTPGAKVLVHCVVG 132
Query: 128 YSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGK 182
SRS TLV+AYLM+ Q++ ++ A+ VRQ+R + PN GFL QLC+L+ +L G+
Sbjct: 133 VSRSATLVLAYLMLHQRLSLRQAVITVRQHRWVFPNRGFLHQLCRLDQQLRGAGQ 187
>gi|51491914 dual specificity phosphatase and pro isomerase domain
containing 1 [Homo sapiens]
Length = 220
Score = 135 bits (339), Expect = 3e-32
Identities = 70/150 (46%), Positives = 103/150 (68%), Gaps = 2/150 (1%)
Query: 31 NEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKA 90
NEV P++Y+G+ + A D +LQK G THVLNAA GR +V+T ++Y+D I Y G++A
Sbjct: 56 NEVWPKLYIGDEATALDRYRLQKAGFTHVLNAAHGR--WNVDTGPDYYRDMDIQYHGVEA 113
Query: 91 NDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSA 150
+D F+LS +F AA FID+AL+ + ++LVHC G SRS TLV+AYLM+ + M + A
Sbjct: 114 DDLPTFDLSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTLVDA 173
Query: 151 LSIVRQNREIGPNDGFLAQLCQLNDRLAKE 180
+ V +NR + PN GFL QL +L+ +L ++
Sbjct: 174 IQQVAKNRCVLPNRGFLKQLRELDKQLVQQ 203
>gi|56237018 testis and skeletal muscle-specific dual specificity
phosphatase isoform 6 [Homo sapiens]
Length = 198
Score = 130 bits (328), Expect = 5e-31
Identities = 71/150 (47%), Positives = 99/150 (66%), Gaps = 2/150 (1%)
Query: 31 NEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKA 90
+EV P +++G+A A+D KL +LGITHV+NAA G+ V+T A FY+ + Y GI+A
Sbjct: 47 DEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGK--FQVDTGAKFYRGMSLEYYGIEA 104
Query: 91 NDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSA 150
+D F+LS YF A +I AL+ GRVLVHC G SRS TLV+A+LM+ + M + A
Sbjct: 105 DDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEA 164
Query: 151 LSIVRQNREIGPNDGFLAQLCQLNDRLAKE 180
+ V+ +R I PN GFL QL L++RL +E
Sbjct: 165 IQTVQAHRNICPNSGFLRQLQVLDNRLGRE 194
>gi|56117822 testis and skeletal muscle-specific dual specificity
phosphatase isoform 3 [Homo sapiens]
Length = 291
Score = 130 bits (328), Expect = 5e-31
Identities = 71/150 (47%), Positives = 99/150 (66%), Gaps = 2/150 (1%)
Query: 31 NEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKA 90
+EV P +++G+A A+D KL +LGITHV+NAA G+ V+T A FY+ + Y GI+A
Sbjct: 140 DEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGK--FQVDTGAKFYRGMSLEYYGIEA 197
Query: 91 NDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSA 150
+D F+LS YF A +I AL+ GRVLVHC G SRS TLV+A+LM+ + M + A
Sbjct: 198 DDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEA 257
Query: 151 LSIVRQNREIGPNDGFLAQLCQLNDRLAKE 180
+ V+ +R I PN GFL QL L++RL +E
Sbjct: 258 IQTVQAHRNICPNSGFLRQLQVLDNRLGRE 287
>gi|56117820 testis and skeletal muscle-specific dual specificity
phosphatase isoform 2 [Homo sapiens]
Length = 248
Score = 130 bits (328), Expect = 5e-31
Identities = 71/150 (47%), Positives = 99/150 (66%), Gaps = 2/150 (1%)
Query: 31 NEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKA 90
+EV P +++G+A A+D KL +LGITHV+NAA G+ V+T A FY+ + Y GI+A
Sbjct: 97 DEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGK--FQVDTGAKFYRGMSLEYYGIEA 154
Query: 91 NDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSA 150
+D F+LS YF A +I AL+ GRVLVHC G SRS TLV+A+LM+ + M + A
Sbjct: 155 DDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEA 214
Query: 151 LSIVRQNREIGPNDGFLAQLCQLNDRLAKE 180
+ V+ +R I PN GFL QL L++RL +E
Sbjct: 215 IQTVQAHRNICPNSGFLRQLQVLDNRLGRE 244
>gi|122937243 dual specificity phosphatase 27 [Homo sapiens]
Length = 1158
Score = 125 bits (315), Expect = 2e-29
Identities = 67/155 (43%), Positives = 97/155 (62%), Gaps = 3/155 (1%)
Query: 26 PSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITY 85
P +EV P +++ SVA + +L++LGITH+LNAA G V T FY I Y
Sbjct: 130 PWNEVDEVWPNVFIAEKSVAVNKGRLKRLGITHILNAAHGTG---VYTGPEFYTGLEIQY 186
Query: 86 LGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKM 145
LG++ +D E ++S +F +A++F+D+AL G+VLV G SRS LV+AYLM+ M
Sbjct: 187 LGVEVDDFPEVDISQHFRKASEFLDEALLTYRGKVLVSSEMGISRSAVLVVAYLMIFHNM 246
Query: 146 DVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE 180
+ AL VR+ R I PN+GFL QL +LN++L +E
Sbjct: 247 AILEALMTVRKKRAIYPNEGFLKQLRELNEKLMEE 281
>gi|13128968 dual specificity phosphatase 26 [Homo sapiens]
Length = 211
Score = 124 bits (312), Expect = 4e-29
Identities = 72/171 (42%), Positives = 106/171 (61%), Gaps = 8/171 (4%)
Query: 7 LSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGR 66
L+V +L LL G + +EV P +Y+G+ +A + +L++LGITHVLNA+ R
Sbjct: 43 LNVFELERLLYTGKTACN----HADEVWPGLYLGDQDMANNRRELRRLGITHVLNASHSR 98
Query: 67 SFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCRE 126
Y+ GI YLG++A+D+ F++S +F+ AADFI +AL+Q G++LVHC
Sbjct: 99 W----RGTPEAYEGLGIRYLGVEAHDSPAFDMSIHFQTAADFIHRALSQPGGKILVHCAV 154
Query: 127 GYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRL 177
G SRS TLV+AYLM+ + + A+ V+ +R I PN GFL QL L+ RL
Sbjct: 155 GVSRSATLVLAYLMLYHHLTLVEAIKKVKDHRGIIPNRGFLRQLLALDRRL 205
>gi|4503421 dual specificity phosphatase 9 [Homo sapiens]
Length = 384
Score = 87.0 bits (214), Expect = 8e-18
Identities = 54/150 (36%), Positives = 78/150 (52%), Gaps = 9/150 (6%)
Query: 32 EVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKAN 91
++ P +Y+G+A + ++ L KLGI ++LN N F K+ Y I +
Sbjct: 206 QILPNLYLGSARDSANLESLAKLGIRYILNVTP-------NLPNFFEKNGDFHYKQIPIS 258
Query: 92 DTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSAL 151
D NLS +F A +FID+AL+Q G VLVHC G SRS T+ +AYLM + + + A
Sbjct: 259 DHWSQNLSRFFPEAIEFIDEALSQNCG-VLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAY 317
Query: 152 SIV-RQNREIGPNDGFLAQLCQLNDRLAKE 180
+V R+ I PN F+ QL L E
Sbjct: 318 DLVKRKKSNISPNFNFMGQLLDFERSLRLE 347
>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
Length = 482
Score = 87.0 bits (214), Expect = 8e-18
Identities = 58/183 (31%), Positives = 88/183 (48%), Gaps = 20/183 (10%)
Query: 7 LSVQDLNDLLSDGSGCYSLPSQPC-----------NEVTPRIYVGNASVAQDIPKLQKLG 55
L +Q+ ++ S SL QP + P +++GN AQD+ +Q+L
Sbjct: 288 LQLQECREVGGGASAASSLLPQPIPTTPDIENAELTPILPFLFLGNEQDAQDLDTMQRLN 347
Query: 56 ITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQ 115
I +V+N H Y+ Y + A D+ + NL YFE A +FI++A
Sbjct: 348 IGYVINVTTHLPLYH-------YEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQC 400
Query: 116 KNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNRE-IGPNDGFLAQLCQLN 174
G +L+HC+ G SRS T+VIAYLM +M + A V+ R I PN F+ QL +
Sbjct: 401 GKG-LLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFE 459
Query: 175 DRL 177
+ L
Sbjct: 460 EDL 462
>gi|4758206 dual specificity phosphatase 2 [Homo sapiens]
Length = 314
Score = 85.9 bits (211), Expect = 2e-17
Identities = 52/147 (35%), Positives = 78/147 (53%), Gaps = 11/147 (7%)
Query: 32 EVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKAN 91
E+ P +++G+ S + D+ LQ GIT VLN V+ + + + Y I
Sbjct: 175 EILPYLFLGSCSHSSDLQGLQACGITAVLN---------VSASCPNHFEGLFRYKSIPVE 225
Query: 92 DTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSAL 151
D Q +SA+F+ A FID + GRVLVHC+ G SRS T+ +AYLM +++ + A
Sbjct: 226 DNQMVEISAWFQEAIGFIDW-VKNSGGRVLVHCQAGISRSATICLAYLMQSRRVRLDEAF 284
Query: 152 SIVRQNR-EIGPNDGFLAQLCQLNDRL 177
V+Q R I PN F+ QL Q ++
Sbjct: 285 DFVKQRRGVISPNFSFMGQLLQFETQV 311
>gi|62865890 dual specificity phosphatase 5 [Homo sapiens]
Length = 384
Score = 85.1 bits (209), Expect = 3e-17
Identities = 51/147 (34%), Positives = 78/147 (53%), Gaps = 11/147 (7%)
Query: 32 EVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKAN 91
E+ P +Y+G+A A L L IT +LN + S + + Y I
Sbjct: 181 EILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACA---------THLHYKWIPVE 231
Query: 92 DTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSAL 151
D+ ++S++F+ A DFID + +K G+VLVHC G SRSPT+ +AYLM ++ +K A
Sbjct: 232 DSHTADISSHFQEAIDFID-CVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAF 290
Query: 152 SIVRQNRE-IGPNDGFLAQLCQLNDRL 177
++Q R + PN GF+ QL Q +
Sbjct: 291 DYIKQRRSMVSPNFGFMGQLLQYESEI 317
>gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo
sapiens]
Length = 217
Score = 84.0 bits (206), Expect = 7e-17
Identities = 61/173 (35%), Positives = 87/173 (50%), Gaps = 24/173 (13%)
Query: 17 SDGSGC---YSLPSQ-PCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEG--RSFMH 70
S G GC L S + P + +G+ A D+ L+K +TH+LN A G +F+
Sbjct: 49 SSGGGCGYVQDLSSDLQVGVIKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFL- 107
Query: 71 VNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSR 130
S TY I D E N+ +YF +FI++A +K+G VLVHC G SR
Sbjct: 108 ----------SDFTYKSISILDLPETNILSYFPECFEFIEEA-KRKDGVVLVHCNAGVSR 156
Query: 131 SPTLVIAYLMMRQKMDVKSALSIVRQNR-EIGPNDGFLAQLCQLNDRLAKEGK 182
+ +VI +LM ++ SA S+V+ R I PN GF+ QL R +EGK
Sbjct: 157 AAAIVIGFLMNSEQTSFTSAFSLVKNARPSICPNSGFMEQL-----RTYQEGK 204
>gi|4758204 dual specificity phosphatase 1 [Homo sapiens]
Length = 367
Score = 83.6 bits (205), Expect = 9e-17
Identities = 50/147 (34%), Positives = 76/147 (51%), Gaps = 11/147 (7%)
Query: 32 EVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKAN 91
E+ P +Y+G+A A L LGIT ++N V+ N + + Y I
Sbjct: 176 EILPFLYLGSAYHASRKDMLDALGITALIN---------VSANCPNHFEGHYQYKSIPVE 226
Query: 92 DTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSAL 151
D + ++S++F A DFID ++ GRV VHC+ G SRS T+ +AYLM ++ + A
Sbjct: 227 DNHKADISSWFNEAIDFID-SIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAF 285
Query: 152 SIVRQNRE-IGPNDGFLAQLCQLNDRL 177
V+Q R I PN F+ QL Q ++
Sbjct: 286 EFVKQRRSIISPNFSFMGQLLQFESQV 312
>gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]
Length = 394
Score = 83.6 bits (205), Expect = 9e-17
Identities = 51/147 (34%), Positives = 82/147 (55%), Gaps = 11/147 (7%)
Query: 32 EVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKAN 91
E+ P +Y+G+A A L LGIT +LN V+++ + + Y I
Sbjct: 198 EILPFLYLGSAYHAARRDMLDALGITALLN---------VSSDCPNHFEGHYQYKCIPVE 248
Query: 92 DTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSAL 151
D + ++S++F A ++ID A+ GRVLVHC+ G SRS T+ +AYLMM++++ ++ A
Sbjct: 249 DNHKADISSWFMEAIEYID-AVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAF 307
Query: 152 SIVRQNRE-IGPNDGFLAQLCQLNDRL 177
V+Q R I PN F+ QL Q ++
Sbjct: 308 EFVKQRRSIISPNFSFMGQLLQFESQV 334
>gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]
Length = 303
Score = 83.6 bits (205), Expect = 9e-17
Identities = 51/147 (34%), Positives = 82/147 (55%), Gaps = 11/147 (7%)
Query: 32 EVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKAN 91
E+ P +Y+G+A A L LGIT +LN V+++ + + Y I
Sbjct: 107 EILPFLYLGSAYHAARRDMLDALGITALLN---------VSSDCPNHFEGHYQYKCIPVE 157
Query: 92 DTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSAL 151
D + ++S++F A ++ID A+ GRVLVHC+ G SRS T+ +AYLMM++++ ++ A
Sbjct: 158 DNHKADISSWFMEAIEYID-AVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAF 216
Query: 152 SIVRQNRE-IGPNDGFLAQLCQLNDRL 177
V+Q R I PN F+ QL Q ++
Sbjct: 217 EFVKQRRSIISPNFSFMGQLLQFESQV 243
>gi|238231453 dual specificity phosphatase 7 [Homo sapiens]
Length = 419
Score = 80.5 bits (197), Expect = 8e-16
Identities = 58/157 (36%), Positives = 79/157 (50%), Gaps = 13/157 (8%)
Query: 17 SDGSGCYSLPSQPCN--EVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTN 74
SDGS S SQP ++ P +Y+G A + ++ L K GI ++LN N
Sbjct: 232 SDGSPVPS--SQPAFPVQILPYLYLGCAKDSTNLDVLGKYGIKYILNVTP-------NLP 282
Query: 75 ANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTL 134
F TY I +D NLS +F A FID+A ++K G VLVHC G SRS T+
Sbjct: 283 NAFEHGGEFTYKQIPISDHWSQNLSQFFPEAISFIDEARSKKCG-VLVHCLAGISRSVTV 341
Query: 135 VIAYLMMRQKMDVKSALSIV-RQNREIGPNDGFLAQL 170
+AYLM + + + A V R+ I PN F+ QL
Sbjct: 342 TVAYLMQKMNLSLNDAYDFVKRKKSNISPNFNFMGQL 378
>gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens]
Length = 381
Score = 80.1 bits (196), Expect = 1e-15
Identities = 57/156 (36%), Positives = 79/156 (50%), Gaps = 11/156 (7%)
Query: 17 SDGSGCY-SLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNA 75
SDGS S PS P E+ P +Y+G A + ++ L++ GI ++LN + N
Sbjct: 194 SDGSPLSNSQPSFPV-EILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGE 252
Query: 76 NFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLV 135
YK I +D NLS +F A FID+A KN VLVHC G SRS T+
Sbjct: 253 FKYKQ-------IPISDHWSQNLSQFFPEAISFIDEARG-KNCGVLVHCLAGISRSVTVT 304
Query: 136 IAYLMMRQKMDVKSALSIVRQNR-EIGPNDGFLAQL 170
+AYLM + + + A IV+ + I PN F+ QL
Sbjct: 305 VAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQL 340
>gi|9910432 dual specificity phosphatase 22 [Homo sapiens]
Length = 184
Score = 73.9 bits (180), Expect = 7e-14
Identities = 50/141 (35%), Positives = 70/141 (49%), Gaps = 12/141 (8%)
Query: 31 NEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKA 90
N++ P +Y+GN A+D +L K +TH+L+ + M G+ YL I A
Sbjct: 6 NKILPGLYIGNFKDARDAEQLSKNKVTHILSVHDSARPML----------EGVKYLCIPA 55
Query: 91 NDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSA 150
D+ NL+ +F+ + FI + + LVHC G SRS TLVIAY+M + A
Sbjct: 56 ADSPSQNLTRHFKESIKFIHECRLRGES-CLVHCLAGVSRSVTLVIAYIMTVTDFGWEDA 114
Query: 151 LSIVRQNRE-IGPNDGFLAQL 170
L VR R PN GF QL
Sbjct: 115 LHTVRAGRSCANPNVGFQRQL 135
>gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
Length = 665
Score = 73.9 bits (180), Expect = 7e-14
Identities = 52/163 (31%), Positives = 81/163 (49%), Gaps = 18/163 (11%)
Query: 27 SQPC--------NEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFY 78
SQPC + P +Y+G + +Q+ GI +VLNA+ + +F
Sbjct: 148 SQPCLPVANIGPTRILPNLYLGCQRDVLNKELMQQNGIGYVLNAS------NTCPKPDFI 201
Query: 79 KDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAY 138
+S +L + ND+ + + +++ DFI++A A NG VLVHC G SRS T+ IAY
Sbjct: 202 PESH--FLRVPVNDSFCEKILPWLDKSVDFIEKAKAS-NGCVLVHCLAGISRSATIAIAY 258
Query: 139 LMMRQKMDVKSALSIVRQNR-EIGPNDGFLAQLCQLNDRLAKE 180
+M R M + A V++ R I PN FL QL ++ +
Sbjct: 259 IMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKIKNQ 301
>gi|239582767 slingshot homolog 3 [Homo sapiens]
Length = 659
Score = 72.8 bits (177), Expect = 2e-13
Identities = 51/165 (30%), Positives = 81/165 (49%), Gaps = 11/165 (6%)
Query: 7 LSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGR 66
L +Q D + + + + P +Y+G+ A ++ +LQ+ +TH+LN A
Sbjct: 306 LPLQQYRDFIDNQMLLLVAQRDRASRIFPHLYLGSEWNAANLEELQRNRVTHILNMAREI 365
Query: 67 SFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCRE 126
NFY + TY ++ D + L +++ FI+ A AQ VLVHC+
Sbjct: 366 D--------NFYPER-FTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGT-HVLVHCKM 415
Query: 127 GYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIG-PNDGFLAQL 170
G SRS V+AY M + + ++ AL V++ R I PN GFL QL
Sbjct: 416 GVSRSAATVLAYAMKQYECSLEQALRHVQELRPIARPNPGFLRQL 460
>gi|21536333 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 72.4 bits (176), Expect = 2e-13
Identities = 45/128 (35%), Positives = 66/128 (51%), Gaps = 9/128 (7%)
Query: 51 LQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFID 110
+Q+L I +V+N H Y+ Y + A D+ + NL YFE A +FI+
Sbjct: 1 MQRLNIGYVINVTTHLPLYH-------YEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIE 53
Query: 111 QALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNRE-IGPNDGFLAQ 169
+A G +L+HC+ G SRS T+VIAYLM +M + A V+ R I PN F+ Q
Sbjct: 54 EAHQCGKG-LLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQ 112
Query: 170 LCQLNDRL 177
L + + L
Sbjct: 113 LLEFEEDL 120
>gi|21536331 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 72.4 bits (176), Expect = 2e-13
Identities = 45/128 (35%), Positives = 66/128 (51%), Gaps = 9/128 (7%)
Query: 51 LQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFID 110
+Q+L I +V+N H Y+ Y + A D+ + NL YFE A +FI+
Sbjct: 1 MQRLNIGYVINVTTHLPLYH-------YEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIE 53
Query: 111 QALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNRE-IGPNDGFLAQ 169
+A G +L+HC+ G SRS T+VIAYLM +M + A V+ R I PN F+ Q
Sbjct: 54 EAHQCGKG-LLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQ 112
Query: 170 LCQLNDRL 177
L + + L
Sbjct: 113 LLEFEEDL 120
>gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo
sapiens]
Length = 223
Score = 72.0 bits (175), Expect = 3e-13
Identities = 51/145 (35%), Positives = 76/145 (52%), Gaps = 14/145 (9%)
Query: 32 EVTPRIYVG--NASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSG---ITYL 86
E+ P +++G ++++ +P LQK GITH++ + N ANF K + YL
Sbjct: 31 EILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQ-------NIEANFIKPNFQQLFRYL 83
Query: 87 GIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMD 146
+ D N+ +F +FID +L Q G+VLVH G SRS VIAY+M M
Sbjct: 84 VLDIADNPVENIIRFFPMTKEFIDGSL-QMGGKVLVHGNAGISRSAAFVIAYIMETFGMK 142
Query: 147 VKSALSIVRQNRE-IGPNDGFLAQL 170
+ A + V++ R I PN GF+ QL
Sbjct: 143 YRDAFAYVQERRFCINPNAGFVHQL 167
>gi|194733759 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 72.0 bits (175), Expect = 3e-13
Identities = 51/145 (35%), Positives = 76/145 (52%), Gaps = 14/145 (9%)
Query: 32 EVTPRIYVG--NASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSG---ITYL 86
E+ P +++G ++++ +P LQK GITH++ + N ANF K + YL
Sbjct: 31 EILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQ-------NIEANFIKPNFQQLFRYL 83
Query: 87 GIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMD 146
+ D N+ +F +FID +L Q G+VLVH G SRS VIAY+M M
Sbjct: 84 VLDIADNPVENIIRFFPMTKEFIDGSL-QMGGKVLVHGNAGISRSAAFVIAYIMETFGMK 142
Query: 147 VKSALSIVRQNRE-IGPNDGFLAQL 170
+ A + V++ R I PN GF+ QL
Sbjct: 143 YRDAFAYVQERRFCINPNAGFVHQL 167
>gi|21687043 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 72.0 bits (175), Expect = 3e-13
Identities = 51/145 (35%), Positives = 76/145 (52%), Gaps = 14/145 (9%)
Query: 32 EVTPRIYVG--NASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSG---ITYL 86
E+ P +++G ++++ +P LQK GITH++ + N ANF K + YL
Sbjct: 31 EILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQ-------NIEANFIKPNFQQLFRYL 83
Query: 87 GIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMD 146
+ D N+ +F +FID +L Q G+VLVH G SRS VIAY+M M
Sbjct: 84 VLDIADNPVENIIRFFPMTKEFIDGSL-QMGGKVLVHGNAGISRSAAFVIAYIMETFGMK 142
Query: 147 VKSALSIVRQNRE-IGPNDGFLAQL 170
+ A + V++ R I PN GF+ QL
Sbjct: 143 YRDAFAYVQERRFCINPNAGFVHQL 167
>gi|29826315 dual specificity phosphatase 15 isoform a [Homo
sapiens]
Length = 235
Score = 67.4 bits (163), Expect = 7e-12
Identities = 46/140 (32%), Positives = 68/140 (48%), Gaps = 12/140 (8%)
Query: 32 EVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKAN 91
+V P +Y+GN A+D+ +L + ITH+++ E + + ITYL I
Sbjct: 7 KVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQD----------ITYLRIPVA 56
Query: 92 DTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSAL 151
DT E + +F+ +FI G LVHC G SRS T+V AY+M + + L
Sbjct: 57 DTPEVPIKKHFKECINFI-HCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVL 115
Query: 152 SIVRQNREI-GPNDGFLAQL 170
++ R I PN GF QL
Sbjct: 116 EAIKATRPIANPNPGFRQQL 135
>gi|153281158 dual specificity phosphatase 8 [Homo sapiens]
Length = 625
Score = 65.5 bits (158), Expect = 3e-11
Identities = 45/152 (29%), Positives = 74/152 (48%), Gaps = 10/152 (6%)
Query: 22 CYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDS 81
C +PS + P +Y+G+ + + + GI++VLNA+ +F +S
Sbjct: 153 CLPVPSVGLTRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCP------KPDFICES 206
Query: 82 GITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMM 141
++ + ND L + +++ +FID+A + +V+VHC G SRS T+ IAY+M
Sbjct: 207 --RFMRVPINDNYCEKLLPWLDKSIEFIDKAKLS-SCQVIVHCLAGISRSATIAIAYIMK 263
Query: 142 RQKMDVKSALSIVRQNR-EIGPNDGFLAQLCQ 172
M A V+ R I PN FL QL +
Sbjct: 264 TMGMSSDDAYRFVKDRRPSISPNFNFLGQLLE 295
>gi|5902002 dual specificity phosphatase 14 [Homo sapiens]
Length = 198
Score = 65.1 bits (157), Expect = 3e-11
Identities = 50/154 (32%), Positives = 78/154 (50%), Gaps = 11/154 (7%)
Query: 32 EVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKAN 91
++T +++G SVA + LQ GIT ++NA + + N N+ + Y+ +
Sbjct: 29 QITSSLFLGRGSVASNRHLLQARGITCIVNAT-----IEI-PNFNWPQ---FEYVKVPLA 79
Query: 92 DTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSAL 151
D + YF+ AD I ++++K+G LVHC G SRS TL IAYLM + + A
Sbjct: 80 DMPHAPIGLYFDTVADKI-HSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAY 138
Query: 152 SIVRQNRE-IGPNDGFLAQLCQLNDRLAKEGKLK 184
+ V+ R I PN GF QL +L + +K
Sbjct: 139 NWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVK 172
>gi|225703077 dual specificity phosphatase 21 [Homo sapiens]
Length = 190
Score = 64.7 bits (156), Expect = 4e-11
Identities = 45/148 (30%), Positives = 72/148 (48%), Gaps = 11/148 (7%)
Query: 31 NEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKA 90
+++T +++ N A D L IT ++NA+ V F++ GI Y+ +
Sbjct: 23 SQITRSLFLSNGVAANDKLLLSSNRITAIVNAS-------VEVVNVFFE--GIQYIKVPV 73
Query: 91 NDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSA 150
D ++ L +F+ AD I + + GR L+HC G SRS +L +AYLM M + A
Sbjct: 74 TDARDSRLYDFFDPIADLI-HTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDA 132
Query: 151 LSIVRQNRE-IGPNDGFLAQLCQLNDRL 177
+ + R I PN+GF QL +L
Sbjct: 133 HTWTKSRRPIIRPNNGFWEQLINYEFKL 160
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,181,285
Number of Sequences: 37866
Number of extensions: 231558
Number of successful extensions: 569
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 61
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 464
Number of HSP's gapped (non-prelim): 75
length of query: 185
length of database: 18,247,518
effective HSP length: 96
effective length of query: 89
effective length of database: 14,612,382
effective search space: 1300501998
effective search space used: 1300501998
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.