Guide to the Human Genome
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Search of human proteins with 4758088

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4758088 galactose-3-O-sulfotransferase 1 [Homo sapiens]
         (423 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4758088 galactose-3-O-sulfotransferase 1 [Homo sapiens]            876   0.0  
gi|124256491 galactose-3-O-sulfotransferase 2 [Homo sapiens]          238   1e-62
gi|31542835 galactose-3-O-sulfotransferase 4 [Homo sapiens]           225   7e-59
gi|14719426 galactose-3-O-sulfotransferase 3 [Homo sapiens]           224   1e-58
gi|24475847 influenza virus NS1A binding protein [Homo sapiens]        33   0.37 
gi|156151369 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex,...    31   2.4  
gi|239753928 PREDICTED: hypothetical protein [Homo sapiens]            30   3.2  
gi|239748470 PREDICTED: hypothetical protein [Homo sapiens]            30   3.2  
gi|239742434 PREDICTED: hypothetical protein XP_002342514 [Homo ...    30   3.2  
gi|109637774 ubiquitin carboxyl-terminal hydrolase CYLD isoform ...    29   7.1  
gi|14165258 ubiquitin carboxyl-terminal hydrolase CYLD isoform 1...    29   7.1  
gi|109637776 ubiquitin carboxyl-terminal hydrolase CYLD isoform ...    29   7.1  

>gi|4758088 galactose-3-O-sulfotransferase 1 [Homo sapiens]
          Length = 423

 Score =  876 bits (2263), Expect = 0.0
 Identities = 423/423 (100%), Positives = 423/423 (100%)

Query: 1   MLPPQKKPWESMAKGLVLGALFTSFLLLVYSYAVPPLHAGLASTTPEAAASCSPPALEPE 60
           MLPPQKKPWESMAKGLVLGALFTSFLLLVYSYAVPPLHAGLASTTPEAAASCSPPALEPE
Sbjct: 1   MLPPQKKPWESMAKGLVLGALFTSFLLLVYSYAVPPLHAGLASTTPEAAASCSPPALEPE 60

Query: 61  AVIRANGSAGECQPRRNIVFLKTHKTASSTLLNILFRFGQKHRLKFAFPNGRNDFDYPTF 120
           AVIRANGSAGECQPRRNIVFLKTHKTASSTLLNILFRFGQKHRLKFAFPNGRNDFDYPTF
Sbjct: 61  AVIRANGSAGECQPRRNIVFLKTHKTASSTLLNILFRFGQKHRLKFAFPNGRNDFDYPTF 120

Query: 121 FARSLVQDYRPGACFNIICNHMRFHYDEVRGLVPTNAIFITVLRDPARLFESSFHYFGPV 180
           FARSLVQDYRPGACFNIICNHMRFHYDEVRGLVPTNAIFITVLRDPARLFESSFHYFGPV
Sbjct: 121 FARSLVQDYRPGACFNIICNHMRFHYDEVRGLVPTNAIFITVLRDPARLFESSFHYFGPV 180

Query: 181 VPLTWKLSAGDKLTEFLQDPDRYYDPNGFNAHYLRNLLFFDLGYDNSLDPSSPQVQEHIL 240
           VPLTWKLSAGDKLTEFLQDPDRYYDPNGFNAHYLRNLLFFDLGYDNSLDPSSPQVQEHIL
Sbjct: 181 VPLTWKLSAGDKLTEFLQDPDRYYDPNGFNAHYLRNLLFFDLGYDNSLDPSSPQVQEHIL 240

Query: 241 EVERRFHLVLLQEYFDESLVLLKDLLCWELEDVLYFKLNARRDSPVPRLSGELYGRATAW 300
           EVERRFHLVLLQEYFDESLVLLKDLLCWELEDVLYFKLNARRDSPVPRLSGELYGRATAW
Sbjct: 241 EVERRFHLVLLQEYFDESLVLLKDLLCWELEDVLYFKLNARRDSPVPRLSGELYGRATAW 300

Query: 301 NMLDSHLYRHFNASFWRKVEAFGRERMAREVAALRHANERMRTICIDGGHAVDAAAIQDE 360
           NMLDSHLYRHFNASFWRKVEAFGRERMAREVAALRHANERMRTICIDGGHAVDAAAIQDE
Sbjct: 301 NMLDSHLYRHFNASFWRKVEAFGRERMAREVAALRHANERMRTICIDGGHAVDAAAIQDE 360

Query: 361 AMQPWQPLGTKSILGYNLKKSIGQRHAQLCRRMLTPEIQYLMDLGANLWVTKLWKFIRDF 420
           AMQPWQPLGTKSILGYNLKKSIGQRHAQLCRRMLTPEIQYLMDLGANLWVTKLWKFIRDF
Sbjct: 361 AMQPWQPLGTKSILGYNLKKSIGQRHAQLCRRMLTPEIQYLMDLGANLWVTKLWKFIRDF 420

Query: 421 LRW 423
           LRW
Sbjct: 421 LRW 423


>gi|124256491 galactose-3-O-sulfotransferase 2 [Homo sapiens]
          Length = 398

 Score =  238 bits (606), Expect = 1e-62
 Identities = 137/344 (39%), Positives = 192/344 (55%), Gaps = 8/344 (2%)

Query: 67  GSAGECQPRRNIVFLKTHKTASSTLLNILFRFGQKHRLKFAFPNG-RNDFDYPTFFARSL 125
           G   E  P  NI+FLKTHKTASST+LNIL+RF + H L  A P G R    YP  F    
Sbjct: 43  GGQAEGPPVTNIMFLKTHKTASSTVLNILYRFAETHNLSVALPAGSRVHLGYPWLFLARY 102

Query: 126 VQDYRPGACFNIICNHMRFHYDEVRGLVPTNAIFITVLRDPARLFESSFHYFGPVVPLTW 185
           V+       FNI+CNH+RF+  +V+ ++P +  + ++LR+P    ESSF Y+    P   
Sbjct: 103 VEGVGSQQRFNIMCNHLRFNLPQVQKVMPNDTFYFSILRNPVFQLESSFIYYKTYAPA-- 160

Query: 186 KLSAGDKLTEFLQDPDRYY-DPNGFNAHYLRNLLFFDLGYDNSLDPSSPQVQEHILEVER 244
                  L  FL  P  +Y D       Y +N ++FD G+D +       V+  I EVER
Sbjct: 161 -FRGAPSLDAFLASPRTFYNDSRHLRNVYAKNNMWFDFGFDPNAQCEEGYVRARIAEVER 219

Query: 245 RFHLVLLQEYFDESLVLLKDLLCWELEDVLYFKLNARRDSPVPRLSGELYGRATAWNMLD 304
           RF LVL+ E+ DESLVLL+  L W L+DV+ F+LN+R    V RLS E   RA +W  LD
Sbjct: 220 RFRLVLIAEHLDESLVLLRRRLRWALDDVVAFRLNSRSARSVARLSPETRERARSWCALD 279

Query: 305 SHLYRHFNASFWRKVEA-FGRERMAREVAALRHANERMRTICI-DGGHAVDAAAIQDEAM 362
             LY HFN + W ++ A  G  R+  EV  LR     + ++C+ DGG   +   I+D  +
Sbjct: 280 WRLYEHFNRTLWAQLRAELGPRRLRGEVERLRARRRELASLCLQDGGALKNHTQIRDPRL 339

Query: 363 QPWQPLGTKSILGYNLKKSIGQRHAQLCRRMLTPEIQYLMDLGA 406
           +P+Q  G   ILGYNL+  +  +   +C+R++ PE+QY+  L A
Sbjct: 340 RPYQS-GKADILGYNLRPGLDNQTLGVCQRLVMPELQYMARLYA 382


>gi|31542835 galactose-3-O-sulfotransferase 4 [Homo sapiens]
          Length = 486

 Score =  225 bits (573), Expect = 7e-59
 Identities = 156/474 (32%), Positives = 220/474 (46%), Gaps = 95/474 (20%)

Query: 9   WESMAKGLVLGALFT-SFLLLVYSYAVPPLHAGLASTTPEAAASCSPPALEPEAVIRANG 67
           W   + G+ LG   T  F L +          GL    P A      P+L P        
Sbjct: 13  WGPRSLGVALGVFMTIGFALQLLGGPFQRRLPGLQLRQPSA------PSLRP-------- 58

Query: 68  SAGECQPRRNIVFLKTHKTASSTLLNILFRFGQKHRLKFAFPNGRNDFDYPTFFARSLVQ 127
           +   C PR+ +VFLKTHK+ SS++L++L R+G +H L+FA P  R  F YP  F  S V+
Sbjct: 59  ALPSCPPRQRLVFLKTHKSGSSSVLSLLHRYGDQHGLRFALP-ARYQFGYPKLFQASRVK 117

Query: 128 DYRPGA-----CFNIICNHMRFHYDEVRGLVPTNAIFITVLRDPARLFESSFHYFGPVVP 182
            YRP        F+I+C+HMRF+  EV  ++P+++ F +++RDPA L  S+F Y+     
Sbjct: 118 GYRPQGGGTQLPFHILCHHMRFNLKEVLQVMPSDSFFFSIVRDPAALARSAFSYYKSTSS 177

Query: 183 LTWKLSAGDKLTEFLQDPDRYYDPNGFNAHYLRNLLFFDLG-------------YDNSLD 229
              K      L  FL +P  +Y P     HY RNLL+FD G                  D
Sbjct: 178 AFRK---SPSLAAFLANPRGFYRPGARGDHYARNLLWFDFGLPFPPEKRAKRGNIHPPRD 234

Query: 230 PSSPQVQ--------------------------EHILEV--------------------- 242
           P+ PQ+Q                          +H  ++                     
Sbjct: 235 PNPPQLQVLPSGAGPRAQTLNPNALIHPVSTVTDHRSQISSPASFDLGSSSFIQWGLAWL 294

Query: 243 ERRFHLVLLQEYFDESLVLLKDLLCWELEDVLYFKLNAR----------RDSPVPRLSGE 292
           +  F LV++ EYFDESLVLL D LCW L+DV+ F  NA+           +S +     +
Sbjct: 295 DSVFDLVMVAEYFDESLVLLADALCWGLDDVVGFMHNAQAGHKQGLSTVSNSGLTAEDRQ 354

Query: 293 LYGRATAWNMLDSHLYRHFNASFWRKVEAFGRERMAREVAALRHANERMRTICIDGGHAV 352
           L  RA AWN LD  LY HFN S W ++E +G+ R+   VA LR   E +   C+ GG A 
Sbjct: 355 LTARARAWNNLDWALYVHFNRSLWARIEKYGQGRLQTAVAELRARREALAKHCLVGGEAS 414

Query: 353 DAAAIQDEAMQPWQPLGTKSILGYNLKKSIGQRHAQLCRRMLTPEIQYLMDLGA 406
           D   I D   +P+Q  G+  +LGY L+  +  +  + C R+ TPE+QY   L A
Sbjct: 415 DPKYITDRRFRPFQ-FGSAKVLGYILRSGLSPQDQEECERLATPELQYKDKLDA 467


>gi|14719426 galactose-3-O-sulfotransferase 3 [Homo sapiens]
          Length = 431

 Score =  224 bits (570), Expect = 1e-58
 Identities = 135/345 (39%), Positives = 188/345 (54%), Gaps = 20/345 (5%)

Query: 72  CQPRRN---------IVFLKTHKTASSTLLNILFRFGQKHRLKFAFPNG--RNDFDYPTF 120
           C P RN         + FLKTHKTA +T+ NILFRF ++H L  A P+    + F YP  
Sbjct: 51  CPPLRNSPPRPKHMTVAFLKTHKTAGTTVQNILFRFAERHNLTVALPHPSCEHQFCYPRN 110

Query: 121 FARSLVQDY-RPGACFNIICNHMRFHYDEVRGLVPTNAIFITVLRDPARLFESSFHYFGP 179
           F+   V    RP    +++ +H+RF   E+  L+P + +++T+LR+PA +FES F Y+  
Sbjct: 111 FSAHFVHPATRPP---HVLASHLRFDRAELERLMPPSTVYVTILREPAAMFESLFSYYNQ 167

Query: 180 VVPLTWKLSAGDKLTEFLQDPDRYYDPNGFNAHYLRNLLFFDLGYDNSLDP--SSPQVQE 237
             P  ++      L  FL+ P+ YY      A +  N L +DLG DN   P   +  +  
Sbjct: 168 YCP-AFRRVPNASLEAFLRAPEAYYRAGEHFAMFAHNTLAYDLGGDNERSPRDDAAYLAG 226

Query: 238 HILEVERRFHLVLLQEYFDESLVLLKDLLCWELEDVLYFKLNAR-RDSPVPRLSGELYGR 296
            I +VE  F LV++ EYFDESLVLL+ LL W+L+DVLY KLNAR   S +  +   L   
Sbjct: 227 LIRQVEEVFSLVMIAEYFDESLVLLRRLLAWDLDDVLYAKLNARAASSRLAAIPAALARA 286

Query: 297 ATAWNMLDSHLYRHFNASFWRKVEAFGRERMAREVAALRHANERMRTICI-DGGHAVDAA 355
           A  WN LD+ LY HFNA+FWR V   GR  + RE   LR A +R+   C  D      AA
Sbjct: 287 ARTWNALDAGLYDHFNATFWRHVARAGRACVEREARELREARQRLLRRCFGDEPLLRPAA 346

Query: 356 AIQDEAMQPWQPLGTKSILGYNLKKSIGQRHAQLCRRMLTPEIQY 400
            I+ + +QPWQP     I+GY+L         + C ++  PE+QY
Sbjct: 347 QIRTKQLQPWQPSRKVDIMGYDLPGGGAGPATEACLKLAMPEVQY 391


>gi|24475847 influenza virus NS1A binding protein [Homo sapiens]
          Length = 642

 Score = 33.5 bits (75), Expect = 0.37
 Identities = 29/97 (29%), Positives = 42/97 (43%), Gaps = 9/97 (9%)

Query: 278 LNARR-DSPVPRLSGELY--GRATAWNMLDSHLYRHFNASFWRKVEAFGRERMAREVAAL 334
           LN RR  S V  L G LY  G A +WN L++    +   + W  +      R    VA L
Sbjct: 498 LNIRRHQSAVCELGGYLYIIGGAESWNCLNTVERYNPENNTWTLIAPMNVARRGAGVAVL 557

Query: 335 RHANERMRTIC--IDGGHAVDAAAIQDEAMQPWQPLG 369
              N ++  +C   DG HA+    + D     W+ +G
Sbjct: 558 ---NGKL-FVCGGFDGSHAISCVEMYDPTRNEWKMMG 590


>gi|156151369 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
           [Homo sapiens]
          Length = 227

 Score = 30.8 bits (68), Expect = 2.4
 Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 6/58 (10%)

Query: 241 EVERRFHLVLLQEYFDESLVLLKDLLCWELEDVLYFKLNARRDSPVPRLSGELYGRAT 298
           E +RR  L +L+E  +E  +++KD+  W++ + ++          VP L GELYG  T
Sbjct: 161 ETDRRT-LQMLRENLEEEAIIMKDVPDWKVGESVFHTTRW-----VPPLIGELYGLRT 212


>gi|239753928 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1179

 Score = 30.4 bits (67), Expect = 3.2
 Identities = 22/57 (38%), Positives = 29/57 (50%), Gaps = 3/57 (5%)

Query: 2   LPPQKKPWESMAKGLVLGALFTSFLLLVYSYAVPPLHAGLASTTPEAAASCSPPALE 58
           LP  + P ++  +  + GA  TSFLL+  S   PPL  G  ST  E  A  SP  L+
Sbjct: 321 LPGLEAPGDASFREPLFGAT-TSFLLVGLSLGRPPLQLGSLST--ETGAGASPGGLD 374


>gi|239748470 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 889

 Score = 30.4 bits (67), Expect = 3.2
 Identities = 22/57 (38%), Positives = 29/57 (50%), Gaps = 3/57 (5%)

Query: 2   LPPQKKPWESMAKGLVLGALFTSFLLLVYSYAVPPLHAGLASTTPEAAASCSPPALE 58
           LP  + P ++  +  + GA  TSFLL+  S   PPL  G  ST  E  A  SP  L+
Sbjct: 321 LPGLEAPGDASFREPLFGAT-TSFLLVGLSLGRPPLQLGSLST--ETGAGASPGGLD 374


>gi|239742434 PREDICTED: hypothetical protein XP_002342514 [Homo
           sapiens]
          Length = 889

 Score = 30.4 bits (67), Expect = 3.2
 Identities = 22/57 (38%), Positives = 29/57 (50%), Gaps = 3/57 (5%)

Query: 2   LPPQKKPWESMAKGLVLGALFTSFLLLVYSYAVPPLHAGLASTTPEAAASCSPPALE 58
           LP  + P ++  +  + GA  TSFLL+  S   PPL  G  ST  E  A  SP  L+
Sbjct: 321 LPGLEAPGDASFREPLFGAT-TSFLLVGLSLGRPPLQLGSLST--ETGAGASPGGLD 374


>gi|109637774 ubiquitin carboxyl-terminal hydrolase CYLD isoform 2
           [Homo sapiens]
          Length = 953

 Score = 29.3 bits (64), Expect = 7.1
 Identities = 35/150 (23%), Positives = 53/150 (35%), Gaps = 8/150 (5%)

Query: 47  EAAASCSPPALEPEAVIRANGSAGECQPRRNIVFLKTHKTASSTLLNILFRFGQKHRLKF 106
           E     +PP +E E +    G     Q   N  +L       STL   LF F        
Sbjct: 566 EVVEENTPPKMEKEGLEIMIGKKKGIQGHYNSCYL------DSTLF-CLFAFSSVLDTVL 618

Query: 107 AFPNGRNDFDYPTFFARSL-VQDYRPGACFNIICNHMRFHYDEVRGLVPTNAIFITVLRD 165
             P  +ND +Y +     L  +   P   +  +C        ++   V   + F +  +D
Sbjct: 619 LRPKEKNDVEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKILEKVEAASGFTSEEKD 678

Query: 166 PARLFESSFHYFGPVVPLTWKLSAGDKLTE 195
           P       FH+   V PL    SAG K+ +
Sbjct: 679 PEEFLNILFHHILRVEPLLKIRSAGQKVQD 708


>gi|14165258 ubiquitin carboxyl-terminal hydrolase CYLD isoform 1
           [Homo sapiens]
          Length = 956

 Score = 29.3 bits (64), Expect = 7.1
 Identities = 35/150 (23%), Positives = 53/150 (35%), Gaps = 8/150 (5%)

Query: 47  EAAASCSPPALEPEAVIRANGSAGECQPRRNIVFLKTHKTASSTLLNILFRFGQKHRLKF 106
           E     +PP +E E +    G     Q   N  +L       STL   LF F        
Sbjct: 569 EVVEENTPPKMEKEGLEIMIGKKKGIQGHYNSCYL------DSTLF-CLFAFSSVLDTVL 621

Query: 107 AFPNGRNDFDYPTFFARSL-VQDYRPGACFNIICNHMRFHYDEVRGLVPTNAIFITVLRD 165
             P  +ND +Y +     L  +   P   +  +C        ++   V   + F +  +D
Sbjct: 622 LRPKEKNDVEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKILEKVEAASGFTSEEKD 681

Query: 166 PARLFESSFHYFGPVVPLTWKLSAGDKLTE 195
           P       FH+   V PL    SAG K+ +
Sbjct: 682 PEEFLNILFHHILRVEPLLKIRSAGQKVQD 711


>gi|109637776 ubiquitin carboxyl-terminal hydrolase CYLD isoform 2
           [Homo sapiens]
          Length = 953

 Score = 29.3 bits (64), Expect = 7.1
 Identities = 35/150 (23%), Positives = 53/150 (35%), Gaps = 8/150 (5%)

Query: 47  EAAASCSPPALEPEAVIRANGSAGECQPRRNIVFLKTHKTASSTLLNILFRFGQKHRLKF 106
           E     +PP +E E +    G     Q   N  +L       STL   LF F        
Sbjct: 566 EVVEENTPPKMEKEGLEIMIGKKKGIQGHYNSCYL------DSTLF-CLFAFSSVLDTVL 618

Query: 107 AFPNGRNDFDYPTFFARSL-VQDYRPGACFNIICNHMRFHYDEVRGLVPTNAIFITVLRD 165
             P  +ND +Y +     L  +   P   +  +C        ++   V   + F +  +D
Sbjct: 619 LRPKEKNDVEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKILEKVEAASGFTSEEKD 678

Query: 166 PARLFESSFHYFGPVVPLTWKLSAGDKLTE 195
           P       FH+   V PL    SAG K+ +
Sbjct: 679 PEEFLNILFHHILRVEPLLKIRSAGQKVQD 708


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.140    0.445 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,177,790
Number of Sequences: 37866
Number of extensions: 766390
Number of successful extensions: 2500
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 2481
Number of HSP's gapped (non-prelim): 13
length of query: 423
length of database: 18,247,518
effective HSP length: 105
effective length of query: 318
effective length of database: 14,271,588
effective search space: 4538364984
effective search space used: 4538364984
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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