Guide to the Human Genome
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Search of human proteins with 4757816

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4757816 ATPase, H+ transporting, lysosomal 21kDa, V0 subunit
b isoform 1 [Homo sapiens]
         (205 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4757816 ATPase, H+ transporting, lysosomal 21kDa, V0 subunit ...   407   e-114
gi|86792634 ATPase, H+ transporting, lysosomal 21kDa, V0 subunit...   310   7e-85
gi|4502313 ATPase, H+ transporting, lysosomal, V0 subunit c [Hom...    92   2e-19
gi|4759144 solute carrier family 9 (sodium/hydrogen exchanger), ...    37   0.012
gi|4557535 solute carrier family 26, member 3 [Homo sapiens]           31   0.84 
gi|50659069 ATP synthase, H+ transporting, mitochondrial F0 comp...    29   2.4  
gi|4885081 ATP synthase, H+ transporting, mitochondrial F0 compl...    29   2.4  
gi|85794840 ATP synthase, H+ transporting, mitochondrial F0 comp...    29   2.4  
gi|4502301 ATP synthase, H+ transporting, mitochondrial F0 compl...    29   2.4  
gi|50659074 ATP synthase, H+ transporting, mitochondrial F0 comp...    29   2.4  
gi|50593533 ATP synthase, H+ transporting, mitochondrial F0 comp...    29   2.4  
gi|155722985 SMC5 protein [Homo sapiens]                               29   3.2  
gi|206597487 solute carrier family 5 (sodium/glucose cotransport...    28   7.1  
gi|206597483 solute carrier family 5 (sodium/glucose cotransport...    28   7.1  
gi|148277022 selenoprotein P isoform 2 [Homo sapiens]                  27   9.3  
gi|4507033 solute carrier family 5 (sodium/glucose cotransporter...    27   9.3  

>gi|4757816 ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
           isoform 1 [Homo sapiens]
          Length = 205

 Score =  407 bits (1047), Expect = e-114
 Identities = 205/205 (100%), Positives = 205/205 (100%)

Query: 1   MTGLALLYSGVFVAFWACALAVGVCYTIFDLGFRFDVAWFLTETSPFMWSNLGIGLAISL 60
           MTGLALLYSGVFVAFWACALAVGVCYTIFDLGFRFDVAWFLTETSPFMWSNLGIGLAISL
Sbjct: 1   MTGLALLYSGVFVAFWACALAVGVCYTIFDLGFRFDVAWFLTETSPFMWSNLGIGLAISL 60

Query: 61  SVVGAAWGIYITGSSIIGGGVKAPRIKTKNLVSIIFCEAVAIYGIIMAIVISNMAEPFSA 120
           SVVGAAWGIYITGSSIIGGGVKAPRIKTKNLVSIIFCEAVAIYGIIMAIVISNMAEPFSA
Sbjct: 61  SVVGAAWGIYITGSSIIGGGVKAPRIKTKNLVSIIFCEAVAIYGIIMAIVISNMAEPFSA 120

Query: 121 TDPKAIGHRNYHAGYSMFGAGLTVGLSNLFCGVCVGIVGSGAALADAQNPSLFVKILIVE 180
           TDPKAIGHRNYHAGYSMFGAGLTVGLSNLFCGVCVGIVGSGAALADAQNPSLFVKILIVE
Sbjct: 121 TDPKAIGHRNYHAGYSMFGAGLTVGLSNLFCGVCVGIVGSGAALADAQNPSLFVKILIVE 180

Query: 181 IFGSAIGLFGVIVAILQTSRVKMGD 205
           IFGSAIGLFGVIVAILQTSRVKMGD
Sbjct: 181 IFGSAIGLFGVIVAILQTSRVKMGD 205


>gi|86792634 ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
           isoform 2 [Homo sapiens]
          Length = 158

 Score =  310 bits (793), Expect = 7e-85
 Identities = 158/158 (100%), Positives = 158/158 (100%)

Query: 48  MWSNLGIGLAISLSVVGAAWGIYITGSSIIGGGVKAPRIKTKNLVSIIFCEAVAIYGIIM 107
           MWSNLGIGLAISLSVVGAAWGIYITGSSIIGGGVKAPRIKTKNLVSIIFCEAVAIYGIIM
Sbjct: 1   MWSNLGIGLAISLSVVGAAWGIYITGSSIIGGGVKAPRIKTKNLVSIIFCEAVAIYGIIM 60

Query: 108 AIVISNMAEPFSATDPKAIGHRNYHAGYSMFGAGLTVGLSNLFCGVCVGIVGSGAALADA 167
           AIVISNMAEPFSATDPKAIGHRNYHAGYSMFGAGLTVGLSNLFCGVCVGIVGSGAALADA
Sbjct: 61  AIVISNMAEPFSATDPKAIGHRNYHAGYSMFGAGLTVGLSNLFCGVCVGIVGSGAALADA 120

Query: 168 QNPSLFVKILIVEIFGSAIGLFGVIVAILQTSRVKMGD 205
           QNPSLFVKILIVEIFGSAIGLFGVIVAILQTSRVKMGD
Sbjct: 121 QNPSLFVKILIVEIFGSAIGLFGVIVAILQTSRVKMGD 158


>gi|4502313 ATPase, H+ transporting, lysosomal, V0 subunit c [Homo
           sapiens]
          Length = 155

 Score = 92.4 bits (228), Expect = 2e-19
 Identities = 49/149 (32%), Positives = 85/149 (57%), Gaps = 10/149 (6%)

Query: 52  LGIGLAISLSVVGAAWGIYITGSSIIGGGVKAPRIKTKNLVSIIFCEAVAIYGIIMAIVI 111
           +G   A+  S +GAA+G   +G+ I    V  P    K+++ ++    +AIYG+++A++I
Sbjct: 17  MGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPEQIMKSIIPVVMAGIIAIYGLVVAVLI 76

Query: 112 SNMAEPFSATDPKAIGHRNYHAGYSMFGAGLTVGLSNLFCGVCVGIVGSGAALADAQNPS 171
           +N     S  D  ++     +  +   GAGL+VGLS L  G  +GIVG       AQ P 
Sbjct: 77  AN-----SLNDDISL-----YKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPR 126

Query: 172 LFVKILIVEIFGSAIGLFGVIVAILQTSR 200
           LFV ++++ IF   +GL+G+IVA++ +++
Sbjct: 127 LFVGMILILIFAEVLGLYGLIVALILSTK 155



 Score = 31.6 bits (70), Expect = 0.49
 Identities = 16/66 (24%), Positives = 30/66 (45%)

Query: 131 YHAGYSMFGAGLTVGLSNLFCGVCVGIVGSGAALADAQNPSLFVKILIVEIFGSAIGLFG 190
           Y + +++ GA   +  S L         G+G A      P   +K +I  +    I ++G
Sbjct: 10  YASFFAVMGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPEQIMKSIIPVVMAGIIAIYG 69

Query: 191 VIVAIL 196
           ++VA+L
Sbjct: 70  LVVAVL 75


>gi|4759144 solute carrier family 9 (sodium/hydrogen exchanger),
           isoform 5 [Homo sapiens]
          Length = 896

 Score = 37.0 bits (84), Expect = 0.012
 Identities = 45/184 (24%), Positives = 76/184 (41%), Gaps = 32/184 (17%)

Query: 33  FRFDVAWFLTETSPFMWSNL---GIGLAISLSVVGAAWGIYITGSSIIG---GGVKAPRI 86
           F F +   + ++  FM S L    +G  ++ +VVG  W  + TG+++ G    G+ APR+
Sbjct: 108 FLFLLPPIVLDSGYFMPSRLFFDNLGAILTYAVVGTLWNAFTTGAALWGLQQAGLVAPRV 167

Query: 87  KTKNLVSIIFCEAVAIYGIIMAIVISNMAEPFSATDPKAI------GHRNYHAGYSMFGA 140
           +   L  ++F   +                  SA DP A+       H N      +FG 
Sbjct: 168 QAGLLDFLLFGSLI------------------SAVDPVAVLAVFEEVHVNETLFIIVFGE 209

Query: 141 G-LTVGLSNLFCGVCVGIVGSGAALADAQNPSLFV-KILIVEIFGSAIGLFGVIVAILQT 198
             L   ++ +   VC   V  G+A   A +    V  + +V + G+A+GL    +  L T
Sbjct: 210 SLLNDAVTVVLYKVCNSFVEMGSANVQATDYLKGVASLFVVSLGGAAVGLVFAFLLALTT 269

Query: 199 SRVK 202
              K
Sbjct: 270 RFTK 273


>gi|4557535 solute carrier family 26, member 3 [Homo sapiens]
          Length = 764

 Score = 30.8 bits (68), Expect = 0.84
 Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 5/63 (7%)

Query: 142 LTVGLSNLFCGVCVGIVGSGAALADAQNPSLFVKILIVEIFGSAIGL-----FGVIVAIL 196
           + +GL N+ CGV  G  GS A    A   S   K  I  + G+ I L      G ++A L
Sbjct: 376 IALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIVVLAIGFLLAPL 435

Query: 197 QTS 199
           Q S
Sbjct: 436 QKS 438


>gi|50659069 ATP synthase, H+ transporting, mitochondrial F0
           complex, subunit C1 precursor [Homo sapiens]
          Length = 136

 Score = 29.3 bits (64), Expect = 2.4
 Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 7/73 (9%)

Query: 129 RNYHAGYSMFGAGL-TVGLSNLFCGVCVGIVGSGAALADAQNPSLFVKILIVEIFG---- 183
           R+        GAG  TVG++    G  +G V     +  A+NPSL  ++    I G    
Sbjct: 61  RDIDTAAKFIGAGAATVGVAG--SGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALS 118

Query: 184 SAIGLFGVIVAIL 196
            A+GLF ++VA L
Sbjct: 119 EAMGLFCLMVAFL 131


>gi|4885081 ATP synthase, H+ transporting, mitochondrial F0 complex,
           subunit C1 precursor [Homo sapiens]
          Length = 136

 Score = 29.3 bits (64), Expect = 2.4
 Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 7/73 (9%)

Query: 129 RNYHAGYSMFGAGL-TVGLSNLFCGVCVGIVGSGAALADAQNPSLFVKILIVEIFG---- 183
           R+        GAG  TVG++    G  +G V     +  A+NPSL  ++    I G    
Sbjct: 61  RDIDTAAKFIGAGAATVGVAG--SGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALS 118

Query: 184 SAIGLFGVIVAIL 196
            A+GLF ++VA L
Sbjct: 119 EAMGLFCLMVAFL 131


>gi|85794840 ATP synthase, H+ transporting, mitochondrial F0
           complex, subunit C2 isoform b precursor [Homo sapiens]
          Length = 198

 Score = 29.3 bits (64), Expect = 2.4
 Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 7/73 (9%)

Query: 129 RNYHAGYSMFGAGL-TVGLSNLFCGVCVGIVGSGAALADAQNPSLFVKILIVEIFG---- 183
           R+        GAG  TVG++    G  +G V     +  A+NPSL  ++    I G    
Sbjct: 123 RDIDTAAKFIGAGAATVGVAG--SGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALS 180

Query: 184 SAIGLFGVIVAIL 196
            A+GLF ++VA L
Sbjct: 181 EAMGLFCLMVAFL 193


>gi|4502301 ATP synthase, H+ transporting, mitochondrial F0 complex,
           subunit C3 precursor [Homo sapiens]
          Length = 142

 Score = 29.3 bits (64), Expect = 2.4
 Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 7/73 (9%)

Query: 129 RNYHAGYSMFGAGL-TVGLSNLFCGVCVGIVGSGAALADAQNPSLFVKILIVEIFG---- 183
           R+        GAG  TVG++    G  +G V     +  A+NPSL  ++    I G    
Sbjct: 67  RDIDTAAKFIGAGAATVGVAG--SGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALS 124

Query: 184 SAIGLFGVIVAIL 196
            A+GLF ++VA L
Sbjct: 125 EAMGLFCLMVAFL 137


>gi|50659074 ATP synthase, H+ transporting, mitochondrial F0
           complex, subunit C3 precursor [Homo sapiens]
          Length = 142

 Score = 29.3 bits (64), Expect = 2.4
 Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 7/73 (9%)

Query: 129 RNYHAGYSMFGAGL-TVGLSNLFCGVCVGIVGSGAALADAQNPSLFVKILIVEIFG---- 183
           R+        GAG  TVG++    G  +G V     +  A+NPSL  ++    I G    
Sbjct: 67  RDIDTAAKFIGAGAATVGVAG--SGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALS 124

Query: 184 SAIGLFGVIVAIL 196
            A+GLF ++VA L
Sbjct: 125 EAMGLFCLMVAFL 137


>gi|50593533 ATP synthase, H+ transporting, mitochondrial F0
           complex, subunit C2 isoform a precursor [Homo sapiens]
          Length = 157

 Score = 29.3 bits (64), Expect = 2.4
 Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 7/73 (9%)

Query: 129 RNYHAGYSMFGAGL-TVGLSNLFCGVCVGIVGSGAALADAQNPSLFVKILIVEIFG---- 183
           R+        GAG  TVG++    G  +G V     +  A+NPSL  ++    I G    
Sbjct: 82  RDIDTAAKFIGAGAATVGVAG--SGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALS 139

Query: 184 SAIGLFGVIVAIL 196
            A+GLF ++VA L
Sbjct: 140 EAMGLFCLMVAFL 152


>gi|155722985 SMC5 protein [Homo sapiens]
          Length = 1101

 Score = 28.9 bits (63), Expect = 3.2
 Identities = 11/31 (35%), Positives = 17/31 (54%)

Query: 145 GLSNLFCGVCVGIVGSGAALADAQNPSLFVK 175
           G S++ C +C+G+ G  A +  A     FVK
Sbjct: 85  GKSSIVCAICLGLAGKPAFMGRADKVGFFVK 115


>gi|206597487 solute carrier family 5 (sodium/glucose
           cotransporter), member 9 isoform 1 [Homo sapiens]
          Length = 706

 Score = 27.7 bits (60), Expect = 7.1
 Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 9/79 (11%)

Query: 3   GLALLYSGVFVAFWACALAVGVCYTIF----DLGFRF----DVAWFLTETSPFMWSNLGI 54
           GL      V V ++   +AVG+  +I      +G  F     ++W+    S  M SN+G 
Sbjct: 32  GLHAYDISVVVIYFVFVIAVGIWSSIRASRGTIGGYFLAGRSMSWWPIGAS-LMSSNVGS 90

Query: 55  GLAISLSVVGAAWGIYITG 73
           GL I L+  GAA G+ + G
Sbjct: 91  GLFIGLAGTGAAGGLAVGG 109


>gi|206597483 solute carrier family 5 (sodium/glucose
           cotransporter), member 9 isoform 2 [Homo sapiens]
          Length = 681

 Score = 27.7 bits (60), Expect = 7.1
 Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 9/79 (11%)

Query: 3   GLALLYSGVFVAFWACALAVGVCYTIF----DLGFRF----DVAWFLTETSPFMWSNLGI 54
           GL      V V ++   +AVG+  +I      +G  F     ++W+    S  M SN+G 
Sbjct: 32  GLHAYDISVVVIYFVFVIAVGIWSSIRASRGTIGGYFLAGRSMSWWPIGAS-LMSSNVGS 90

Query: 55  GLAISLSVVGAAWGIYITG 73
           GL I L+  GAA G+ + G
Sbjct: 91  GLFIGLAGTGAAGGLAVGG 109


>gi|148277022 selenoprotein P isoform 2 [Homo sapiens]
          Length = 411

 Score = 27.3 bits (59), Expect = 9.3
 Identities = 10/20 (50%), Positives = 15/20 (75%)

Query: 41 LTETSPFMWSNLGIGLAISL 60
          +T T+P MW +LG+ LA+ L
Sbjct: 24 ITRTTPAMWRSLGLALALCL 43


>gi|4507033 solute carrier family 5 (sodium/glucose cotransporter),
           member 2 [Homo sapiens]
          Length = 672

 Score = 27.3 bits (59), Expect = 9.3
 Identities = 23/66 (34%), Positives = 35/66 (53%), Gaps = 6/66 (9%)

Query: 133 AGYSM--FGAGLTVGLSNLFCGVCVGIVGSGA----ALADAQNPSLFVKILIVEIFGSAI 186
           AG SM  +  G ++  SN+  G  VG+ G+GA    A+A  +  +LFV +L+  +F    
Sbjct: 58  AGRSMVWWPVGASLFASNIGSGHFVGLAGTGAASGLAVAGFEWNALFVVLLLGWLFAPVY 117

Query: 187 GLFGVI 192
              GVI
Sbjct: 118 LTAGVI 123


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.143    0.441 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,541,565
Number of Sequences: 37866
Number of extensions: 255078
Number of successful extensions: 582
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 570
Number of HSP's gapped (non-prelim): 20
length of query: 205
length of database: 18,247,518
effective HSP length: 97
effective length of query: 108
effective length of database: 14,574,516
effective search space: 1574047728
effective search space used: 1574047728
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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