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Search of human proteins with 46559769
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46559769 adenosine A3 receptor isoform 1 [Homo sapiens]
(347 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46559769 adenosine A3 receptor isoform 1 [Homo sapiens] 697 0.0
gi|130978672 adenosine A3 receptor isoform 3 [Homo sapiens] 476 e-134
gi|4501953 adenosine A3 receptor isoform 2 [Homo sapiens] 227 1e-59
gi|115305569 adenosine A1 receptor [Homo sapiens] 123 2e-28
gi|4501947 adenosine A1 receptor [Homo sapiens] 123 2e-28
gi|5921992 adenosine A2a receptor [Homo sapiens] 113 3e-25
gi|4501951 adenosine A2b receptor [Homo sapiens] 110 2e-24
gi|4504541 5-hydroxytryptamine (serotonin) receptor 2C [Homo sap... 69 6e-12
gi|4557265 beta-1-adrenergic receptor [Homo sapiens] 67 2e-11
gi|222080049 5-hydroxytryptamine (serotonin) receptor 2B [Homo s... 67 2e-11
gi|10835175 5-hydroxytryptamine (serotonin) receptor 2A [Homo sa... 65 7e-11
gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens] 65 7e-11
gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens] 64 2e-10
gi|55956923 5-hydroxytryptamine (serotonin) receptor 1A [Homo sa... 63 3e-10
gi|17986270 dopamine receptor D2 isoform short [Homo sapiens] 63 4e-10
gi|4503385 dopamine receptor D2 isoform long [Homo sapiens] 63 4e-10
gi|16604258 neuropeptide FF receptor 2 isoform 2 [Homo sapiens] 62 8e-10
gi|221316654 neuropeptide FF receptor 2 isoform 1 [Homo sapiens] 62 8e-10
gi|221316652 neuropeptide FF receptor 2 isoform 3 [Homo sapiens] 62 8e-10
gi|89191863 dopamine receptor D3 isoform e [Homo sapiens] 62 8e-10
gi|89191861 dopamine receptor D3 isoform a [Homo sapiens] 62 8e-10
gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens] 62 1e-09
gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens] 62 1e-09
gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens] 62 1e-09
gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens] 62 1e-09
gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens] 62 1e-09
gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens] 62 1e-09
gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens] 62 1e-09
gi|4502819 cholinergic receptor, muscarinic 3 [Homo sapiens] 61 1e-09
gi|7108336 cholinergic receptor, muscarinic 5 [Homo sapiens] 61 1e-09
>gi|46559769 adenosine A3 receptor isoform 1 [Homo sapiens]
Length = 347
Score = 697 bits (1798), Expect = 0.0
Identities = 347/347 (100%), Positives = 347/347 (100%)
Query: 1 MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA 60
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
Sbjct: 1 MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA 60
Query: 61 VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRFRI 120
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRFRI
Sbjct: 61 VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRFRI 120
Query: 121 PGLPGCILSFQLKVCFLPVMWLFILLSLALISDAMVMDEKVKRSFVLDTASAICNYNAHY 180
PGLPGCILSFQLKVCFLPVMWLFILLSLALISDAMVMDEKVKRSFVLDTASAICNYNAHY
Sbjct: 121 PGLPGCILSFQLKVCFLPVMWLFILLSLALISDAMVMDEKVKRSFVLDTASAICNYNAHY 180
Query: 181 KNHPKYWCRGYFRDYCNIIAFSPNSTNHVALRDTGNQLIVTMSCLTKEDTGWYWCGIQRD 240
KNHPKYWCRGYFRDYCNIIAFSPNSTNHVALRDTGNQLIVTMSCLTKEDTGWYWCGIQRD
Sbjct: 181 KNHPKYWCRGYFRDYCNIIAFSPNSTNHVALRDTGNQLIVTMSCLTKEDTGWYWCGIQRD 240
Query: 241 FARDDMDFTELIVTDDKGTLANDFWSGKDLSGNKTRSCKAPKVVRKADRSRTSILIICIL 300
FARDDMDFTELIVTDDKGTLANDFWSGKDLSGNKTRSCKAPKVVRKADRSRTSILIICIL
Sbjct: 241 FARDDMDFTELIVTDDKGTLANDFWSGKDLSGNKTRSCKAPKVVRKADRSRTSILIICIL 300
Query: 301 ITGLGIISVISHLTKRRRSQRNRRVGNTLKPFSRVLTPKEMAPTEQM 347
ITGLGIISVISHLTKRRRSQRNRRVGNTLKPFSRVLTPKEMAPTEQM
Sbjct: 301 ITGLGIISVISHLTKRRRSQRNRRVGNTLKPFSRVLTPKEMAPTEQM 347
>gi|130978672 adenosine A3 receptor isoform 3 [Homo sapiens]
Length = 266
Score = 476 bits (1226), Expect = e-134
Identities = 230/231 (99%), Positives = 231/231 (100%)
Query: 117 RFRIPGLPGCILSFQLKVCFLPVMWLFILLSLALISDAMVMDEKVKRSFVLDTASAICNY 176
+FRIPGLPGCILSFQLKVCFLPVMWLFILLSLALISDAMVMDEKVKRSFVLDTASAICNY
Sbjct: 36 QFRIPGLPGCILSFQLKVCFLPVMWLFILLSLALISDAMVMDEKVKRSFVLDTASAICNY 95
Query: 177 NAHYKNHPKYWCRGYFRDYCNIIAFSPNSTNHVALRDTGNQLIVTMSCLTKEDTGWYWCG 236
NAHYKNHPKYWCRGYFRDYCNIIAFSPNSTNHVALRDTGNQLIVTMSCLTKEDTGWYWCG
Sbjct: 96 NAHYKNHPKYWCRGYFRDYCNIIAFSPNSTNHVALRDTGNQLIVTMSCLTKEDTGWYWCG 155
Query: 237 IQRDFARDDMDFTELIVTDDKGTLANDFWSGKDLSGNKTRSCKAPKVVRKADRSRTSILI 296
IQRDFARDDMDFTELIVTDDKGTLANDFWSGKDLSGNKTRSCKAPKVVRKADRSRTSILI
Sbjct: 156 IQRDFARDDMDFTELIVTDDKGTLANDFWSGKDLSGNKTRSCKAPKVVRKADRSRTSILI 215
Query: 297 ICILITGLGIISVISHLTKRRRSQRNRRVGNTLKPFSRVLTPKEMAPTEQM 347
ICILITGLGIISVISHLTKRRRSQRNRRVGNTLKPFSRVLTPKEMAPTEQM
Sbjct: 216 ICILITGLGIISVISHLTKRRRSQRNRRVGNTLKPFSRVLTPKEMAPTEQM 266
>gi|4501953 adenosine A3 receptor isoform 2 [Homo sapiens]
Length = 318
Score = 227 bits (578), Expect = 1e-59
Identities = 117/119 (98%), Positives = 119/119 (100%)
Query: 1 MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA 60
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
Sbjct: 1 MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA 60
Query: 61 VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRFR 119
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVR++
Sbjct: 61 VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYK 119
>gi|115305569 adenosine A1 receptor [Homo sapiens]
Length = 326
Score = 123 bits (309), Expect = 2e-28
Identities = 66/133 (49%), Positives = 95/133 (71%), Gaps = 9/133 (6%)
Query: 7 ALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVM 66
++S YI +E+ I L ++ GNVLVI VK+N +L+ TF FIVSLA+AD+AVG LV+
Sbjct: 4 SISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVI 63
Query: 67 PLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRFRIPGLP-- 124
PLAI++++G +F++CL + C +LI T +SI++LLAIAVDRYLRVK+ +R+++ P
Sbjct: 64 PLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRR 123
Query: 125 ------GC-ILSF 130
GC ILSF
Sbjct: 124 AAVAIAGCWILSF 136
>gi|4501947 adenosine A1 receptor [Homo sapiens]
Length = 326
Score = 123 bits (309), Expect = 2e-28
Identities = 66/133 (49%), Positives = 95/133 (71%), Gaps = 9/133 (6%)
Query: 7 ALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVM 66
++S YI +E+ I L ++ GNVLVI VK+N +L+ TF FIVSLA+AD+AVG LV+
Sbjct: 4 SISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVI 63
Query: 67 PLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRFRIPGLP-- 124
PLAI++++G +F++CL + C +LI T +SI++LLAIAVDRYLRVK+ +R+++ P
Sbjct: 64 PLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRR 123
Query: 125 ------GC-ILSF 130
GC ILSF
Sbjct: 124 AAVAIAGCWILSF 136
>gi|5921992 adenosine A2a receptor [Homo sapiens]
Length = 412
Score = 113 bits (282), Expect = 3e-25
Identities = 55/109 (50%), Positives = 77/109 (70%)
Query: 10 LANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLA 69
+ + YIT+E+ I + AI+GNVLV V LN +LQ T YF+VSLA ADIAVGVL +P A
Sbjct: 4 MGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFA 63
Query: 70 IVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRF 118
I +S G + CLF+ C +L+ T +SI SLLAIA+DRY+ +++ +R+
Sbjct: 64 ITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRY 112
>gi|4501951 adenosine A2b receptor [Homo sapiens]
Length = 332
Score = 110 bits (274), Expect = 2e-24
Identities = 52/112 (46%), Positives = 74/112 (66%)
Query: 8 LSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMP 67
L + Y+ +E+ I ++ GNVLV V +LQT T YF+VSLA AD+AVG+ +P
Sbjct: 3 LETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIP 62
Query: 68 LAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRFR 119
AI +SLG FY CLF+ C +L+ T +SI SLLA+AVDRYL + + +R++
Sbjct: 63 FAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYK 114
>gi|4504541 5-hydroxytryptamine (serotonin) receptor 2C [Homo
sapiens]
Length = 458
Score = 68.9 bits (167), Expect = 6e-12
Identities = 40/97 (41%), Positives = 59/97 (60%), Gaps = 3/97 (3%)
Query: 20 IFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMP---LAIVVSLGI 76
+ I + I GN+LVI V + L T YF++SLA+AD+ VG+LVMP LAI+
Sbjct: 61 VIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVW 120
Query: 77 TIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVK 113
+ Y C L ++F+ ASIM L AI++DRY+ ++
Sbjct: 121 PLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIR 157
>gi|4557265 beta-1-adrenergic receptor [Homo sapiens]
Length = 477
Score = 67.0 bits (162), Expect = 2e-11
Identities = 48/128 (37%), Positives = 66/128 (51%), Gaps = 9/128 (7%)
Query: 22 IGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPL--AIVVSLGITIH 79
I L + GNVLVI + P LQT T FI+SLA AD+ +G+LV+P IVV
Sbjct: 68 IVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYG 127
Query: 80 FYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRV-------KLTVRFRIPGLPGCILSFQL 132
+ C T + ++ ASI +L IA+DRYL + L R R GL + +
Sbjct: 128 SFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARGLVCTVWAISA 187
Query: 133 KVCFLPVM 140
V FLP++
Sbjct: 188 LVSFLPIL 195
>gi|222080049 5-hydroxytryptamine (serotonin) receptor 2B [Homo
sapiens]
Length = 481
Score = 67.0 bits (162), Expect = 2e-11
Identities = 42/99 (42%), Positives = 59/99 (59%), Gaps = 13/99 (13%)
Query: 27 IVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYS---- 82
I GN LVI V L LQ T YF++SLA+AD+ VG+ VMP+A+ +TI F +
Sbjct: 69 IGGNTLVILAVSLEKKLQYATNYFLMSLAVADLLVGLFVMPIAL-----LTIMFEAMWPL 123
Query: 83 ----CLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVR 117
C L ++F+ ASIM L AI+VDRY+ +K ++
Sbjct: 124 PLVLCPAWLFLDVLFSTASIMHLCAISVDRYIAIKKPIQ 162
>gi|10835175 5-hydroxytryptamine (serotonin) receptor 2A [Homo
sapiens]
Length = 471
Score = 65.5 bits (158), Expect = 7e-11
Identities = 38/93 (40%), Positives = 55/93 (59%), Gaps = 3/93 (3%)
Query: 24 LCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMP---LAIVVSLGITIHF 80
+ I GN+LVI V L LQ T YF++SLA+AD+ +G LVMP L I+ +
Sbjct: 86 ILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPS 145
Query: 81 YSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVK 113
C L ++F+ ASIM L AI++DRY+ ++
Sbjct: 146 KLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQ 178
>gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]
Length = 520
Score = 65.5 bits (158), Expect = 7e-11
Identities = 45/126 (35%), Positives = 71/126 (56%), Gaps = 9/126 (7%)
Query: 2 PNNSTALSLANVTYITMEIFIGLC-------AIVGNVLVICVVKLNPSLQTTTFYFIVSL 54
PN +++ S IT I +GL AIVGN+LVI V N L+T T YFIV+L
Sbjct: 28 PNQTSSNSTLPQLDITRAISVGLVLGAFILFAIVGNILVILSVACNRHLRTPTNYFIVNL 87
Query: 55 ALADIAVGVLVMPLAIVVS-LGI-TIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRV 112
A+AD+ + V+P + + LG + C + ++ ASI+SL AI++DRY+ V
Sbjct: 88 AMADLLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGV 147
Query: 113 KLTVRF 118
+ ++++
Sbjct: 148 RYSLQY 153
>gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens]
Length = 408
Score = 63.9 bits (154), Expect = 2e-10
Identities = 40/99 (40%), Positives = 58/99 (58%), Gaps = 6/99 (6%)
Query: 24 LCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHF--- 80
L + GN+LVI + P LQT T F+ SLA AD+ +G+LV+P A +L +T H+
Sbjct: 49 LATVGGNLLVIVAIAWTPRLQTMTNVFVTSLAAADLVMGLLVVPPA--ATLALTGHWPLG 106
Query: 81 -YSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRF 118
C T + ++ ASI +L A+AVDRYL V +R+
Sbjct: 107 ATGCELWTSVDVLCVTASIETLCALAVDRYLAVTNPLRY 145
>gi|55956923 5-hydroxytryptamine (serotonin) receptor 1A [Homo
sapiens]
Length = 422
Score = 63.2 bits (152), Expect = 3e-10
Identities = 44/143 (30%), Positives = 73/143 (51%), Gaps = 9/143 (6%)
Query: 4 NSTALSLANVTY-ITMEIFIG---LCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADI 59
N+T +S V+Y + + +G CA++GN V+ + L SLQ Y I SLA+ D+
Sbjct: 24 NTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDL 83
Query: 60 AVGVLVMPLAIVVSL--GITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVR 117
V VLV+P+A + + T+ +C L ++ +SI+ L AIA+DRY + +
Sbjct: 84 MVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPID 143
Query: 118 F---RIPGLPGCILSFQLKVCFL 137
+ R P ++S + FL
Sbjct: 144 YVNKRTPRRAAALISLTWLIGFL 166
>gi|17986270 dopamine receptor D2 isoform short [Homo sapiens]
Length = 414
Score = 62.8 bits (151), Expect = 4e-10
Identities = 41/107 (38%), Positives = 61/107 (57%), Gaps = 4/107 (3%)
Query: 15 YITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAI---V 71
Y T+ + + GNVLV V +LQTTT Y IVSLA+AD+ V LVMP + V
Sbjct: 37 YATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEV 96
Query: 72 VSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRF 118
V + +F+T +++ T ASI++L AI++DRY V + + +
Sbjct: 97 VGEWKFSRIHCDIFVTLDVMMCT-ASILNLCAISIDRYTAVAMPMLY 142
>gi|4503385 dopamine receptor D2 isoform long [Homo sapiens]
Length = 443
Score = 62.8 bits (151), Expect = 4e-10
Identities = 41/107 (38%), Positives = 61/107 (57%), Gaps = 4/107 (3%)
Query: 15 YITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAI---V 71
Y T+ + + GNVLV V +LQTTT Y IVSLA+AD+ V LVMP + V
Sbjct: 37 YATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEV 96
Query: 72 VSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRF 118
V + +F+T +++ T ASI++L AI++DRY V + + +
Sbjct: 97 VGEWKFSRIHCDIFVTLDVMMCT-ASILNLCAISIDRYTAVAMPMLY 142
>gi|16604258 neuropeptide FF receptor 2 isoform 2 [Homo sapiens]
Length = 420
Score = 62.0 bits (149), Expect = 8e-10
Identities = 50/186 (26%), Positives = 90/186 (48%), Gaps = 28/186 (15%)
Query: 10 LANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLA 69
+A + I+ + LC ++GN +V +V N + T T FI++LA++D+ VG+ MP+
Sbjct: 44 VAAIFIISYFLIFFLC-MMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPIT 102
Query: 70 IV--VSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRFRIPGLPGCI 127
++ + G C + I AS+ +L+AIAVDR+ V + ++
Sbjct: 103 LLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKL------- 155
Query: 128 LSFQLKVCFLPVMWLFILLSLALISDAMVM----DEKVKRSFVLDTASAICNYNAHYKNH 183
+K F+ +M +++ L++ ++S + VM +EK R N+ K
Sbjct: 156 ---TIKTAFVIIMIIWV-LAITIMSPSAVMLHVQEEKYYR----------VRLNSQNKTS 201
Query: 184 PKYWCR 189
P YWCR
Sbjct: 202 PVYWCR 207
>gi|221316654 neuropeptide FF receptor 2 isoform 1 [Homo sapiens]
Length = 522
Score = 62.0 bits (149), Expect = 8e-10
Identities = 50/186 (26%), Positives = 90/186 (48%), Gaps = 28/186 (15%)
Query: 10 LANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLA 69
+A + I+ + LC ++GN +V +V N + T T FI++LA++D+ VG+ MP+
Sbjct: 146 VAAIFIISYFLIFFLC-MMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPIT 204
Query: 70 IV--VSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRFRIPGLPGCI 127
++ + G C + I AS+ +L+AIAVDR+ V + ++
Sbjct: 205 LLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKL------- 257
Query: 128 LSFQLKVCFLPVMWLFILLSLALISDAMVM----DEKVKRSFVLDTASAICNYNAHYKNH 183
+K F+ +M +++ L++ ++S + VM +EK R N+ K
Sbjct: 258 ---TIKTAFVIIMIIWV-LAITIMSPSAVMLHVQEEKYYR----------VRLNSQNKTS 303
Query: 184 PKYWCR 189
P YWCR
Sbjct: 304 PVYWCR 309
>gi|221316652 neuropeptide FF receptor 2 isoform 3 [Homo sapiens]
Length = 423
Score = 62.0 bits (149), Expect = 8e-10
Identities = 50/186 (26%), Positives = 90/186 (48%), Gaps = 28/186 (15%)
Query: 10 LANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLA 69
+A + I+ + LC ++GN +V +V N + T T FI++LA++D+ VG+ MP+
Sbjct: 47 VAAIFIISYFLIFFLC-MMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPIT 105
Query: 70 IV--VSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRFRIPGLPGCI 127
++ + G C + I AS+ +L+AIAVDR+ V + ++
Sbjct: 106 LLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKL------- 158
Query: 128 LSFQLKVCFLPVMWLFILLSLALISDAMVM----DEKVKRSFVLDTASAICNYNAHYKNH 183
+K F+ +M +++ L++ ++S + VM +EK R N+ K
Sbjct: 159 ---TIKTAFVIIMIIWV-LAITIMSPSAVMLHVQEEKYYR----------VRLNSQNKTS 204
Query: 184 PKYWCR 189
P YWCR
Sbjct: 205 PVYWCR 210
>gi|89191863 dopamine receptor D3 isoform e [Homo sapiens]
Length = 367
Score = 62.0 bits (149), Expect = 8e-10
Identities = 43/121 (35%), Positives = 64/121 (52%), Gaps = 5/121 (4%)
Query: 4 NSTALSLA--NVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAV 61
NST S A + Y + L + GN LV V +LQTTT Y +VSLA+AD+ V
Sbjct: 19 NSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLV 78
Query: 62 GVLVMPLAIVVSLGITIHFYS---CLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRF 118
LVMP + + + + +S C L ++ ASI++L AI++DRY V + V +
Sbjct: 79 ATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHY 138
Query: 119 R 119
+
Sbjct: 139 Q 139
>gi|89191861 dopamine receptor D3 isoform a [Homo sapiens]
Length = 400
Score = 62.0 bits (149), Expect = 8e-10
Identities = 43/121 (35%), Positives = 64/121 (52%), Gaps = 5/121 (4%)
Query: 4 NSTALSLA--NVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAV 61
NST S A + Y + L + GN LV V +LQTTT Y +VSLA+AD+ V
Sbjct: 19 NSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLV 78
Query: 62 GVLVMPLAIVVSLGITIHFYS---CLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRF 118
LVMP + + + + +S C L ++ ASI++L AI++DRY V + V +
Sbjct: 79 ATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHY 138
Query: 119 R 119
+
Sbjct: 139 Q 139
>gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]
Length = 359
Score = 61.6 bits (148), Expect = 1e-09
Identities = 61/200 (30%), Positives = 96/200 (48%), Gaps = 21/200 (10%)
Query: 9 SLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTT-TFYFIVSLALADIAVGVLVMP 67
S+ V +T + L AI+GN+LV+ V + L+ T YFIVSLA AD+ V VLVMP
Sbjct: 16 SVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMP 75
Query: 68 LAIVVSLGITIHFYS---CLFMTCLLLIFTHASIMSLLAIAVDRYLRV---KLTVRFRIP 121
+ L I Y CL T L ++ T ASI L I++DRY + L R ++
Sbjct: 76 FG-AIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMT 134
Query: 122 GLPGCILSFQLKVCFLPVMWLFILLSLALISDAMVMDEKVKRSFVLDTASAICNYNAHYK 181
L ++ L C++ ++ L + ++ ++D KR F ++ S C +
Sbjct: 135 PLR---IALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMV--- 188
Query: 182 NHPKYWCRGYFRDYCNIIAF 201
N P + C+++AF
Sbjct: 189 NKP-------YAITCSVVAF 201
>gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]
Length = 428
Score = 61.6 bits (148), Expect = 1e-09
Identities = 61/200 (30%), Positives = 96/200 (48%), Gaps = 21/200 (10%)
Query: 9 SLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTT-TFYFIVSLALADIAVGVLVMP 67
S+ V +T + L AI+GN+LV+ V + L+ T YFIVSLA AD+ V VLVMP
Sbjct: 16 SVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMP 75
Query: 68 LAIVVSLGITIHFYS---CLFMTCLLLIFTHASIMSLLAIAVDRYLRV---KLTVRFRIP 121
+ L I Y CL T L ++ T ASI L I++DRY + L R ++
Sbjct: 76 FG-AIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMT 134
Query: 122 GLPGCILSFQLKVCFLPVMWLFILLSLALISDAMVMDEKVKRSFVLDTASAICNYNAHYK 181
L ++ L C++ ++ L + ++ ++D KR F ++ S C +
Sbjct: 135 PLR---IALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMV--- 188
Query: 182 NHPKYWCRGYFRDYCNIIAF 201
N P + C+++AF
Sbjct: 189 NKP-------YAITCSVVAF 201
>gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]
Length = 360
Score = 61.6 bits (148), Expect = 1e-09
Identities = 61/200 (30%), Positives = 96/200 (48%), Gaps = 21/200 (10%)
Query: 9 SLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTT-TFYFIVSLALADIAVGVLVMP 67
S+ V +T + L AI+GN+LV+ V + L+ T YFIVSLA AD+ V VLVMP
Sbjct: 16 SVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMP 75
Query: 68 LAIVVSLGITIHFYS---CLFMTCLLLIFTHASIMSLLAIAVDRYLRV---KLTVRFRIP 121
+ L I Y CL T L ++ T ASI L I++DRY + L R ++
Sbjct: 76 FG-AIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMT 134
Query: 122 GLPGCILSFQLKVCFLPVMWLFILLSLALISDAMVMDEKVKRSFVLDTASAICNYNAHYK 181
L ++ L C++ ++ L + ++ ++D KR F ++ S C +
Sbjct: 135 PLR---IALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMV--- 188
Query: 182 NHPKYWCRGYFRDYCNIIAF 201
N P + C+++AF
Sbjct: 189 NKP-------YAITCSVVAF 201
>gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]
Length = 387
Score = 61.6 bits (148), Expect = 1e-09
Identities = 61/200 (30%), Positives = 96/200 (48%), Gaps = 21/200 (10%)
Query: 9 SLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTT-TFYFIVSLALADIAVGVLVMP 67
S+ V +T + L AI+GN+LV+ V + L+ T YFIVSLA AD+ V VLVMP
Sbjct: 16 SVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMP 75
Query: 68 LAIVVSLGITIHFYS---CLFMTCLLLIFTHASIMSLLAIAVDRYLRV---KLTVRFRIP 121
+ L I Y CL T L ++ T ASI L I++DRY + L R ++
Sbjct: 76 FG-AIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMT 134
Query: 122 GLPGCILSFQLKVCFLPVMWLFILLSLALISDAMVMDEKVKRSFVLDTASAICNYNAHYK 181
L ++ L C++ ++ L + ++ ++D KR F ++ S C +
Sbjct: 135 PLR---IALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMV--- 188
Query: 182 NHPKYWCRGYFRDYCNIIAF 201
N P + C+++AF
Sbjct: 189 NKP-------YAITCSVVAF 201
>gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]
Length = 378
Score = 61.6 bits (148), Expect = 1e-09
Identities = 61/200 (30%), Positives = 96/200 (48%), Gaps = 21/200 (10%)
Query: 9 SLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTT-TFYFIVSLALADIAVGVLVMP 67
S+ V +T + L AI+GN+LV+ V + L+ T YFIVSLA AD+ V VLVMP
Sbjct: 16 SVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMP 75
Query: 68 LAIVVSLGITIHFYS---CLFMTCLLLIFTHASIMSLLAIAVDRYLRV---KLTVRFRIP 121
+ L I Y CL T L ++ T ASI L I++DRY + L R ++
Sbjct: 76 FG-AIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMT 134
Query: 122 GLPGCILSFQLKVCFLPVMWLFILLSLALISDAMVMDEKVKRSFVLDTASAICNYNAHYK 181
L ++ L C++ ++ L + ++ ++D KR F ++ S C +
Sbjct: 135 PLR---IALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMV--- 188
Query: 182 NHPKYWCRGYFRDYCNIIAF 201
N P + C+++AF
Sbjct: 189 NKP-------YAITCSVVAF 201
>gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]
Length = 388
Score = 61.6 bits (148), Expect = 1e-09
Identities = 61/200 (30%), Positives = 96/200 (48%), Gaps = 21/200 (10%)
Query: 9 SLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTT-TFYFIVSLALADIAVGVLVMP 67
S+ V +T + L AI+GN+LV+ V + L+ T YFIVSLA AD+ V VLVMP
Sbjct: 16 SVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMP 75
Query: 68 LAIVVSLGITIHFYS---CLFMTCLLLIFTHASIMSLLAIAVDRYLRV---KLTVRFRIP 121
+ L I Y CL T L ++ T ASI L I++DRY + L R ++
Sbjct: 76 FG-AIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMT 134
Query: 122 GLPGCILSFQLKVCFLPVMWLFILLSLALISDAMVMDEKVKRSFVLDTASAICNYNAHYK 181
L ++ L C++ ++ L + ++ ++D KR F ++ S C +
Sbjct: 135 PLR---IALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMV--- 188
Query: 182 NHPKYWCRGYFRDYCNIIAF 201
N P + C+++AF
Sbjct: 189 NKP-------YAITCSVVAF 201
>gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens]
Length = 572
Score = 61.6 bits (148), Expect = 1e-09
Identities = 40/128 (31%), Positives = 71/128 (55%), Gaps = 14/128 (10%)
Query: 24 LCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYS- 82
L A+ GN+LVI V N LQT T YFIV+LA+AD+ + V+P + + + + F++
Sbjct: 108 LMAVAGNLLVILSVACNRHLQTVTNYFIVNLAVADLLLSATVLPFSATMEV---LGFWAF 164
Query: 83 ----CLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRFRIPGLPGCILSFQLKVCFLP 138
C + ++ ASI+SL I+VDRY+ V+ ++++ I++ + L
Sbjct: 165 GRAFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKY------PAIMTERKAAAILA 218
Query: 139 VMWLFILL 146
++W+ L+
Sbjct: 219 LLWVVALV 226
>gi|4502819 cholinergic receptor, muscarinic 3 [Homo sapiens]
Length = 590
Score = 61.2 bits (147), Expect = 1e-09
Identities = 33/100 (33%), Positives = 57/100 (57%), Gaps = 2/100 (2%)
Query: 22 IGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPL--AIVVSLGITIH 79
+ L I+GN+LVI K+N L+T YF++SLA AD+ +GV+ M L ++ +
Sbjct: 78 LALVTIIGNILVIVSFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFTTYIIMNRWALG 137
Query: 80 FYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRFR 119
+C + + ++AS+M+LL I+ DRY + + +R
Sbjct: 138 NLACDLWLAIDYVASNASVMNLLVISFDRYFSITRPLTYR 177
>gi|7108336 cholinergic receptor, muscarinic 5 [Homo sapiens]
Length = 532
Score = 61.2 bits (147), Expect = 1e-09
Identities = 35/114 (30%), Positives = 60/114 (52%), Gaps = 2/114 (1%)
Query: 13 VTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPL--AI 70
+T + + L IVGNVLV+ K+N L+T Y+++SLA AD+ +G+ M L
Sbjct: 31 ITIAAVTAVVSLITIVGNVLVMISFKVNSQLKTVNNYYLLSLACADLIIGIFSMNLYTTY 90
Query: 71 VVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRFRIPGLP 124
++ + +C L + ++AS+M+LL I+ DRY + + +R P
Sbjct: 91 ILMGRWALGSLACDLWLALDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTP 144
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.328 0.140 0.431
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,696,334
Number of Sequences: 37866
Number of extensions: 463195
Number of successful extensions: 2487
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 410
Number of HSP's successfully gapped in prelim test: 229
Number of HSP's that attempted gapping in prelim test: 1713
Number of HSP's gapped (non-prelim): 686
length of query: 347
length of database: 18,247,518
effective HSP length: 103
effective length of query: 244
effective length of database: 14,347,320
effective search space: 3500746080
effective search space used: 3500746080
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.