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Search of human proteins with 46359075
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46359075 zinc finger protein 423 [Homo sapiens]
(1284 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46359075 zinc finger protein 423 [Homo sapiens] 2707 0.0
gi|24308069 zinc finger protein 521 [Homo sapiens] 1680 0.0
gi|239757212 PREDICTED: similar to hCG1773661 [Homo sapiens] 258 3e-68
gi|239751718 PREDICTED: similar to hCG1773661 [Homo sapiens] 258 3e-68
gi|239746221 PREDICTED: hypothetical protein XP_002343677 [Homo ... 258 3e-68
gi|118600985 zinc finger protein 91 [Homo sapiens] 257 4e-68
gi|6005976 zinc finger protein 208 [Homo sapiens] 244 4e-64
gi|210031219 zinc finger protein 845 [Homo sapiens] 231 3e-60
gi|122937213 zinc finger protein 99 [Homo sapiens] 221 5e-57
gi|119120877 zinc finger protein 721 [Homo sapiens] 216 1e-55
gi|154800445 zinc finger protein 62 homolog [Homo sapiens] 210 6e-54
gi|211057416 zinc finger protein 841 [Homo sapiens] 207 5e-53
gi|157167158 zinc finger protein 808 [Homo sapiens] 204 6e-52
gi|25014093 zinc finger protein 585B [Homo sapiens] 195 3e-49
gi|40217792 zinc finger protein 585A [Homo sapiens] 194 3e-49
gi|22749331 zinc finger protein 585A [Homo sapiens] 194 3e-49
gi|156627573 zinc finger protein 836 [Homo sapiens] 193 8e-49
gi|209954795 zinc finger protein 761 [Homo sapiens] 189 2e-47
gi|23308729 zinc finger protein 268 [Homo sapiens] 187 4e-47
gi|172072608 zinc finger protein 624 [Homo sapiens] 187 7e-47
gi|156547246 zinc finger protein 160 [Homo sapiens] 186 9e-47
gi|38788302 zinc finger protein 160 [Homo sapiens] 186 9e-47
gi|38788288 zinc finger protein 160 [Homo sapiens] 186 9e-47
gi|49574543 zinc finger protein 616 [Homo sapiens] 186 1e-46
gi|194018469 zinc finger protein 546 [Homo sapiens] 180 7e-45
gi|22095393 zinc finger protein 420 [Homo sapiens] 179 2e-44
gi|55769537 zinc finger protein 658 [Homo sapiens] 176 1e-43
gi|150378520 zinc finger protein 594 [Homo sapiens] 174 5e-43
gi|68303809 zinc finger protein 43 [Homo sapiens] 169 1e-41
gi|54792150 zinc finger protein 473 [Homo sapiens] 165 3e-40
>gi|46359075 zinc finger protein 423 [Homo sapiens]
Length = 1284
Score = 2707 bits (7016), Expect = 0.0
Identities = 1284/1284 (100%), Positives = 1284/1284 (100%)
Query: 1 MHKKRVEEGEASDFSLAWDSSVTAAGGLEGEPECDQKTSRALEDRNSVTSQEERNEDDED 60
MHKKRVEEGEASDFSLAWDSSVTAAGGLEGEPECDQKTSRALEDRNSVTSQEERNEDDED
Sbjct: 1 MHKKRVEEGEASDFSLAWDSSVTAAGGLEGEPECDQKTSRALEDRNSVTSQEERNEDDED 60
Query: 61 MEDESIYTCDHCQQDFESLADLTDHRAHRCPGDGDDDPQLSWVASSPSSKDVASPTQMIG 120
MEDESIYTCDHCQQDFESLADLTDHRAHRCPGDGDDDPQLSWVASSPSSKDVASPTQMIG
Sbjct: 61 MEDESIYTCDHCQQDFESLADLTDHRAHRCPGDGDDDPQLSWVASSPSSKDVASPTQMIG 120
Query: 121 DGCDLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRS 180
DGCDLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRS
Sbjct: 121 DGCDLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRS 180
Query: 181 RDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSH 240
RDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSH
Sbjct: 181 RDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSH 240
Query: 241 MQAHKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHC 300
MQAHKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHC
Sbjct: 241 MQAHKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHC 300
Query: 301 PEVFVDENTLLAHIHQAHANQKHKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPV 360
PEVFVDENTLLAHIHQAHANQKHKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPV
Sbjct: 301 PEVFVDENTLLAHIHQAHANQKHKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPV 360
Query: 361 LGSVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFN 420
LGSVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFN
Sbjct: 361 LGSVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFN 420
Query: 421 SLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAF 480
SLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAF
Sbjct: 421 SLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAF 480
Query: 481 HCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAH 540
HCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAH
Sbjct: 481 HCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAH 540
Query: 541 CSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSK 600
CSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSK
Sbjct: 541 CSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSK 600
Query: 601 AEQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLR 660
AEQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLR
Sbjct: 601 AEQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLR 660
Query: 661 KQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLY 720
KQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLY
Sbjct: 661 KQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLY 720
Query: 721 HCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKA 780
HCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKA
Sbjct: 721 HCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKA 780
Query: 781 HKCIFCGETFSTEVELQCHITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENG 840
HKCIFCGETFSTEVELQCHITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENG
Sbjct: 781 HKCIFCGETFSTEVELQCHITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENG 840
Query: 841 TANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVL 900
TANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVL
Sbjct: 841 TANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVL 900
Query: 901 LQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYM 960
LQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYM
Sbjct: 901 LQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYM 960
Query: 961 CPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGF 1020
CPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGF
Sbjct: 961 CPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGF 1020
Query: 1021 RCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLV 1080
RCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLV
Sbjct: 1021 RCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLV 1080
Query: 1081 KLDVNGLPYGLCAGCMARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQ 1140
KLDVNGLPYGLCAGCMARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQ
Sbjct: 1081 KLDVNGLPYGLCAGCMARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQ 1140
Query: 1141 VDHRDLTPETSGPRKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHEC 1200
VDHRDLTPETSGPRKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHEC
Sbjct: 1141 VDHRDLTPETSGPRKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHEC 1200
Query: 1201 KLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYD 1260
KLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYD
Sbjct: 1201 KLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYD 1260
Query: 1261 CSQCPQKFFFQTELQNHTMSQHAQ 1284
CSQCPQKFFFQTELQNHTMSQHAQ
Sbjct: 1261 CSQCPQKFFFQTELQNHTMSQHAQ 1284
>gi|24308069 zinc finger protein 521 [Homo sapiens]
Length = 1311
Score = 1680 bits (4351), Expect = 0.0
Identities = 822/1309 (62%), Positives = 988/1309 (75%), Gaps = 68/1309 (5%)
Query: 31 EPECDQKTSRALEDRNSVTSQEERNEDDEDMEDESIYTCDHCQQDFESLADLTDHRAHRC 90
+P C K ED ++ ++ R ED E++EDE++++CD C Q FESL+D+T+H+ ++C
Sbjct: 14 DPNC--KLEDKTEDGEALDCKK-RPEDGEELEDEAVHSCDSCLQVFESLSDITEHKINQC 70
Query: 91 P----GDGDDDPQLSWVASSPSSKDVASPTQMIGDGCDLGLGEEEGGTGLPYPCQFCDKS 146
D +DDP SW ASSPSSKD SP+ G+GCD G EEEGG GLPYPCQFCDKS
Sbjct: 71 QLTDGVDVEDDPTCSWPASSPSSKDQTSPSH--GEGCDFG--EEEGGPGLPYPCQFCDKS 126
Query: 147 FIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRS 206
F RLSYLK HEQ HSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC EC+AAFSRS
Sbjct: 127 FSRLSYLKHHEQSHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCSECDAAFSRS 186
Query: 207 DHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHL---AKSEKEAKKDDF 263
DHLKIHLKTH+S+KP+KC +C+RGF S+SSL HMQ H++NK+ ++ E KD
Sbjct: 187 DHLKIHLKTHTSNKPYKCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKMKDTQ 246
Query: 264 MCDYCEDTFSQTEELEKHVLTRHPQLS---EKADLQCIHCPEVFVDENTLLAHIHQAHAN 320
C CE+ F E+L+KH+ HP+ S ++A LQC++C E+FV+E +L+ H+ Q H+
Sbjct: 247 KCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSG 306
Query: 321 QK-HKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDSSASVE 379
+K + C +C E F +VE +Y H+DSH+QP+S NHS SP V S+SS TPDS+ SV+
Sbjct: 307 EKKNSCSICSESFHTVEELYSHMDSHQQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSVD 366
Query: 380 RGSTPDST--LKPLRGQKKMRDDGQGWT-------KVVYSCPYCSKRDFNSLAVLEIHLK 430
+ ++ + RG+K+ T KV YSC YC+K+ F+SLAVL+IHLK
Sbjct: 367 SSTMVEAAPPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLFSSLAVLQIHLK 426
Query: 431 TIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISA--FHCNYCPEM 488
T+H DKP+Q+H CQ CL+ +P+LYNLNEH++++H+ P + + A + CN+C E+
Sbjct: 427 TMHLDKPEQAHICQYCLEVLPSLYNLNEHLKQVHEAQD-PGLIVSAMPAIVYQCNFCSEV 485
Query: 489 FADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKL 548
D+N+LQEHIR SH N D +NAFFC C MGFLT+SSL EHI+Q HC + ++
Sbjct: 486 VNDLNTLQEHIRCSHGFANPAAKD-SNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRF 544
Query: 549 ESPVV-QPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLA----HSKKSKAEQ 603
SPV+ P + +EVYSC YCTNSPIF S+LKL KHIKENHKNIPLA H+ K
Sbjct: 545 GSPVLGTPKEPVVEVYSCSYCTNSPIFNSVLKLNKHIKENHKNIPLALNYIHNGKKSRAL 604
Query: 604 SPVSS-DVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQ 662
SP+S +E +S K + A + GEY CNQC K+++ +SFQTHLK HL+ +L K
Sbjct: 605 SPLSPVAIEQTSLKMMQAVGGAPARPTGEYICNQCGAKYTSLDSFQTHLKTHLDTVLPKL 664
Query: 663 ACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHC 722
CPQC ++F +QESLL+H+T+H+M TST+Y+CESCDKQF+SVDDLQKHLLDMHTFV + C
Sbjct: 665 TCPQCNKEFPNQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRC 724
Query: 723 TLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHK 782
TLCQEVFDSKVSIQ+HLAVKHSNEKK+YRCT+CNWDFR E DLQ+HVKH+HL N K HK
Sbjct: 725 TLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVHK 784
Query: 783 CIFCGETFSTEVELQCHITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENGTA 842
CIFCGE+F TEVELQCHITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVF+ T N
Sbjct: 785 CIFCGESFGTEVELQCHITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCGT 844
Query: 843 NGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQ 902
NG K E +LQ +L + E+ NSH+ SE+DVD SEPMYGCDICGAAYTME LLQ
Sbjct: 845 NGASEQVQK--EEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYGCDICGAAYTMETLLQ 902
Query: 903 NHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCP 962
NH+LRDHNIRPGE +KKAE IKG++KCNVCSRTFFSENGLREH+QTH GP KHYMCP
Sbjct: 903 NHQLRDHNIRPGESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCP 962
Query: 963 ICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRC 1022
ICGERFPSLLTLTEHKVTHSKSLDTG CRICKMPLQSEEEF+EHCQMHPDLRNSLTGFRC
Sbjct: 963 ICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDLRNSLTGFRC 1022
Query: 1023 VVCMQTVTSTLELKIHGTFHMQKLA-GSSAASSPNGQGLQKLYKCALCLKEFRSKQDLVK 1081
VVCMQTVTSTLELKIHGTFHMQK GS+ ++ GQ +QKLYKCA CLKEFRSKQDLVK
Sbjct: 1023 VVCMQTVTSTLELKIHGTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCLKEFRSKQDLVK 1082
Query: 1082 LDVNGLPYGLCAGCMARSANGQVGGLAPPEPADRPCAG------------------LRCP 1123
LD+NGLPYGLCAGC+ S + G PP +RP G RC
Sbjct: 1083 LDINGLPYGLCAGCVNLSKSASPGINVPP-GTNRPGLGQNENLSAIEGKGKVGGLKTRCS 1141
Query: 1124 ECSVKFESAEDLESHMQVDHRDLTPETSGPR-KGTQTSPVPR--------KKTYQCIKCQ 1174
C+VKFES +L++H+Q HR+L P+++ + K Q SP+PR KKTYQCIKCQ
Sbjct: 1142 SCNVKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPMPRISPSQSDEKKTYQCIKCQ 1201
Query: 1175 MTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVC 1234
M F NE +IQ+HVANHMI+EG+NHECKLC+Q FDSPAKL CHLIEHSFEGMGGTFKCPVC
Sbjct: 1202 MVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQCHLIEHSFEGMGGTFKCPVC 1261
Query: 1235 FTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNHTMSQHA 1283
FTVFVQANKLQQHIF+ HGQEDKIYDC+QCPQKFFFQTELQNHTM+QH+
Sbjct: 1262 FTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTELQNHTMTQHS 1310
Score = 172 bits (435), Expect = 2e-42
Identities = 195/806 (24%), Positives = 298/806 (36%), Gaps = 157/806 (19%)
Query: 562 VYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLS 621
V+SC C +F S+ +T+H K N + + V D S P S
Sbjct: 46 VHSCDSCLQ--VFESLSDITEH-KINQCQL---------TDGVDVEDDPTCSWPASSPSS 93
Query: 622 ASANSISNGE--------------YPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQC 667
S S+GE YPC CD FS + H + H + L K C C
Sbjct: 94 KDQTSPSHGEGCDFGEEEGGPGLPYPCQFCDKSFSRLSYLKHHEQSHSDKLPFK--CTYC 151
Query: 668 KEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQE 727
F + S +H+ +H T Y C CD FS D L+ HL + Y C +C+
Sbjct: 152 SRLFKHKRSRDRHIKLH--TGDKKYHCSECDAAFSRSDHLKIHLKTHTSNKPYKCAICRR 209
Query: 728 VFDSKVSIQVHLAVKHSNE--------------KKMYRCTACNWDFRKEADLQVHVKHSH 773
F S S+ H+ V N+ K +C+ C F DLQ H+ H
Sbjct: 210 GFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQKHIAECH 269
Query: 774 L----GNPAKAHKCIFCGETFSTEVELQCHIT-THS--KKYNCKFCSKAFHAIILLEKHL 826
A +C++C E F E L H+ HS KK +C CS++FH + L H+
Sbjct: 270 PECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSICSESFHTVEELYSHM 329
Query: 827 REKHCVFDAATENGTANGVPPMATKKAEPA-------DLQGMLLKNPEAPNSH---EASE 876
+ H ++ + + + V T + D M+ P P S A++
Sbjct: 330 -DSHQQPESCNHSNSPSLVTVGYTSVSSTTPDSNLSVDSSTMVEAAPPIPKSRGRKRAAQ 388
Query: 877 DDVDASEPM-------YGCDICGAA-YTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKG 928
D + P Y C C ++ +LQ H H +P +
Sbjct: 389 QTPDMTGPSSKQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKPEQ------------- 435
Query: 929 SHKCNVCSRTFFSENGLREHL-QTHRG----------PAKHYMCPICGERFPSLLTLTEH 977
+H C C S L EHL Q H PA Y C C E L TL EH
Sbjct: 436 AHICQYCLEVLPSLYNLNEHLKQVHEAQDPGLIVSAMPAIVYQCNFCSEVVNDLNTLQEH 495
Query: 978 -KVTH------SKSLDTGTCRICKMPLQSEEEFIEHC-QMHPDLRNSLTGFRCVVCMQTV 1029
+ +H +K + C C M ++ EH Q+H DL S G V
Sbjct: 496 IRCSHGFANPAAKDSNAFFCPHCYMGFLTDSSLEEHIRQVHCDLSGSRFG-------SPV 548
Query: 1030 TSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLVKLDVNGLPY 1089
T + + ++ + S +SP + KL K + + L +N +
Sbjct: 549 LGTPKEPV-----VEVYSCSYCTNSPIFNSVLKLNK------HIKENHKNIPLALNYIHN 597
Query: 1090 GLCAGCMARSANG----------QVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHM 1139
G + ++ + Q G AP RP C +C K+ S + ++H+
Sbjct: 598 GKKSRALSPLSPVAIEQTSLKMMQAVGGAPA----RPTGEYICNQCGAKYTSLDSFQTHL 653
Query: 1140 QVDHRDLTPETSGPRKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHE 1199
+ + P+ + C +C F N+ + HV H + +
Sbjct: 654 KTHLDTVLPKLT------------------CPQCNKEFPNQESLLKHVTIHFMITSTYYI 695
Query: 1200 CKLCNQMFDSPAKLLCHLIE-HSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKI 1258
C+ C++ F S L HL++ H+F F+C +C VF +Q H+ H E K+
Sbjct: 696 CESCDKQFTSVDDLQKHLLDMHTFV----FFRCTLCQEVFDSKVSIQLHLAVKHSNEKKV 751
Query: 1259 YDCSQCPQKFFFQTELQNHTMSQHAQ 1284
Y C+ C F +T+LQ H H +
Sbjct: 752 YRCTSCNWDFRNETDLQLHVKHNHLE 777
Score = 125 bits (314), Expect = 3e-28
Identities = 165/790 (20%), Positives = 286/790 (36%), Gaps = 147/790 (18%)
Query: 66 IYTCDHCQQD--FESLADLTDHRAHRCPGDGDDDPQLSWVASSPSSKDVASPTQMIGDGC 123
+Y+C +C F S+ L H + L+++ + S+ ++ + + +
Sbjct: 559 VYSCSYCTNSPIFNSVLKLNKHIKEN---HKNIPLALNYIHNGKKSRALSPLSPVAIEQT 615
Query: 124 DLGLGEEEGG-----TGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFK--CTYCSRLFK 176
L + + GG TG Y C C + L + H + H D + K C C++ F
Sbjct: 616 SLKMMQAVGGAPARPTG-EYICNQCGAKYTSLDSFQTHLKTHLDTVLPKLTCPQCNKEFP 674
Query: 177 HKRSRDRHIKLH--TGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSST 234
++ S +H+ +H Y C C+ F+ D L+ HL + F+CT+C+ F S
Sbjct: 675 NQESLLKHVTIHFMITSTYYICESCDKQFTSVDDLQKHLLDMHTFVFFRCTLCQEVFDSK 734
Query: 235 SSLQSHMQAHKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKAD 294
S+Q H+ N++ + + C C F +L+ HV H + K
Sbjct: 735 VSIQLHLAVKHSNEKKV-----------YRCTSCNWDFRNETDLQLHVKHNHLENQGKVH 783
Query: 295 LQCIHCPEVFVDENTLLAHIHQAHANQKHKCPMCPEQFSSVEGVYCHL------------ 342
+CI C E F E L HI ++K+ C C + F ++ + HL
Sbjct: 784 -KCIFCGESFGTEVELQCHI--TTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFETKTP 840
Query: 343 --------------------------DSHRQPDSSNHSV-SPDPVLGSVASMSSATPDSS 375
+SH D S V + +P+ G + A
Sbjct: 841 NCGTNGASEQVQKEEVELQTLLTNSQESHNSHDGSEEDVDTSEPMYG--CDICGAAYTME 898
Query: 376 ASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHAD 435
++ D ++P G+ + K Y C CS+ F+ + E H++T H
Sbjct: 899 TLLQNHQLRDHNIRP--GESAIVKKKAELIKGNYKCNVCSRTFFSENGLRE-HMQT-HLG 954
Query: 436 KPQQSHTCQICLDSMPTLYNLNEHVRKLHKN-----------------------HAYPVM 472
P + + C IC + P+L L EH K+ +P +
Sbjct: 955 -PVKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGNCRICKMPLQSEEEFLEHCQMHPDL 1013
Query: 473 QFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNA---------FFCNQCS 523
+ +++ F C C + L+ H H N S + C C
Sbjct: 1014 R-NSLTGFRCVVCMQTVTSTLELKIH-GTFHMQKTGNGSAVQTTGRGQHVQKLYKCASCL 1071
Query: 524 MGFLTESSLTE----HIQQAHCS--VGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSI 577
F ++ L + + C+ V +K SP + + P TN P G
Sbjct: 1072 KEFRSKQDLVKLDINGLPYGLCAGCVNLSKSASPGI----------NVPPGTNRPGLGQN 1121
Query: 578 LKLTK-----------------HIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRL 620
L+ ++K ++ H + E P S+ ++ +P+ +
Sbjct: 1122 ENLSAIEGKGKVGGLKTRCSSCNVKFESESELQNHIQTIHRELVPDSNSTQLKTPQVSPM 1181
Query: 621 SASANSISNGE--YPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLL 678
+ S S+ + Y C +C + F N Q H+ H+ C C + FDS L
Sbjct: 1182 PRISPSQSDEKKTYQCIKCQMVFYNEWDIQVHVANHMIDEGLNHECKLCSQTFDSPAKLQ 1241
Query: 679 QHLTVH-YMTTSTHYVCESCDKQFSSVDDLQKHLLDMH--TFVLYHCTLCQEVFDSKVSI 735
HL H + + C C F + LQ+H+ H +Y CT C + F + +
Sbjct: 1242 CHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFSAHGQEDKIYDCTQCPQKFFFQTEL 1301
Query: 736 QVHLAVKHSN 745
Q H +HS+
Sbjct: 1302 QNHTMTQHSS 1311
Score = 50.1 bits (118), Expect = 1e-05
Identities = 64/309 (20%), Positives = 99/309 (32%), Gaps = 71/309 (22%)
Query: 993 CKMPLQSEEEFIEHCQMHPDLRNSLTG---FRCVVCMQTVTSTLELKIHGTFHMQKLAGS 1049
CK+ ++E+ C+ P+ L C C+Q S ++ H Q G
Sbjct: 17 CKLEDKTEDGEALDCKKRPEDGEELEDEAVHSCDSCLQVFESLSDITEHKINQCQLTDGV 76
Query: 1050 SAASSPNGQGLQKLYKCALCLKEFRSKQDLVKLDVNGLPYGLCAGCMARSANGQVGGLAP 1109
P C+ SK G +G + GG
Sbjct: 77 DVEDDPT---------CSWPASSPSSKDQTSPSHGEGCDFG-----------EEEGGPGL 116
Query: 1110 PEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGPRKGTQTSPVPRKKTYQ 1169
P P C C F L+ H Q H D P ++
Sbjct: 117 PYP---------CQFCDKSFSRLSYLKHHEQ-SHSDKLP-------------------FK 147
Query: 1170 CIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTF 1229
C C F+++R H+ H ++ + C C+ F L HL H+ +
Sbjct: 148 CTYCSRLFKHKRSRDRHIKLHTGDK--KYHCSECDAAFSRSDHLKIHLKTHT---SNKPY 202
Query: 1230 KCPVCFTVFVQANKLQQHIFAVHGQED-----------KIYD---CSQCPQKFFFQTELQ 1275
KC +C F+ ++ L H+ +D K+ D CSQC + F F +LQ
Sbjct: 203 KCAICRRGFLSSSSLHGHMQVHERNKDGSQSGSRMEDWKMKDTQKCSQCEEGFDFPEDLQ 262
Query: 1276 NHTMSQHAQ 1284
H H +
Sbjct: 263 KHIAECHPE 271
>gi|239757212 PREDICTED: similar to hCG1773661 [Homo sapiens]
Length = 1119
Score = 258 bits (659), Expect = 3e-68
Identities = 272/1162 (23%), Positives = 426/1162 (36%), Gaps = 211/1162 (18%)
Query: 137 PYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 196
PY + C +F S +H++IH+ + PF+C C + F + H ++HTG+K Y C
Sbjct: 102 PYKYKKCGNAFKFSSTFTKHKRIHTGETPFRCEECGKAFNQSSNLTDHKRIHTGEKTYKC 161
Query: 197 HECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEK 256
EC AF S + H H++ KP+KC C + F+ S+L+ H H K +
Sbjct: 162 EECGKAFKGSSNFNAHKVIHTAEKPYKCEDCGKTFNHFSALRKHKIIHTGKKPY------ 215
Query: 257 EAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQ 316
K+++ C FSQ+ L KH + + + +C C + F + L H
Sbjct: 216 --KREE-----CGKAFSQSSTLRKHEIIH----TGEKPYKCEECGKAFKWSSKLTVHKVV 264
Query: 317 AHANQKHKCPMCPEQFSSVEGVYCHLDSH--RQPDSSNHSVSPDPVLGSVASMSSATPDS 374
+ +KC C + FS + H H ++P A SS+T
Sbjct: 265 HTGEKPYKCEECGKAFSQFSTLKKHKIIHTGKKPYKCEEC--------GKAFNSSSTLMK 316
Query: 375 SASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHA 434
+ G P Y C C K F + L H K IH
Sbjct: 317 HKIIHTGEKP------------------------YKCEECGKA-FRQSSHLTRH-KAIHT 350
Query: 435 DKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINS 494
++ + C+ C + +L H + +H + C C + F+ ++
Sbjct: 351 G--EKPYKCEECGKAFNHFSDLRRH-KIIHTGK----------KPYKCEECGKAFSQSST 397
Query: 495 LQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEH---------IQQAHCSVG- 544
L+ H ++ H G + C +C F S LT H + C
Sbjct: 398 LRNH-QIIH--------TGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAF 448
Query: 545 ---SAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKA 601
SA + V+ + ++Y C C + SIL K I K K+
Sbjct: 449 KHFSALRKHKVIHTRE---KLYKCEECGKAFNNSSILAKHKIIHTGKKPYKCEECGKAFR 505
Query: 602 EQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRK 661
+ S ++ + + ++ Y C +C FS+F + + H +H +
Sbjct: 506 QSSHLTRHKAIHTGEK-------------PYKCEECGKAFSHFSALRRHKIIHTG--KKP 550
Query: 662 QACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYH 721
C +C + F +L +H +H T Y CE C K F L H +
Sbjct: 551 YKCEECGKAFSHFSALRRHKIIH--TGEKPYKCEECGKAFKWSSKLTVHKVIHTAEKPCK 608
Query: 722 CTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAH 781
C C + F +++ H + H+ E K+Y+C C F + L +KH + K +
Sbjct: 609 CEECGKSFKHFSALRKHKVI-HTRE-KLYKCEECVKAFNSFSAL---MKHKVIHTGEKPY 663
Query: 782 KCIFCGETFSTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFDAATEN 839
KC CG+ F +L H I T K C+ C KAF L KH
Sbjct: 664 KCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKH-------------K 710
Query: 840 GTANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEV 899
G P ++ A Q L+ E + + E Y C+ CG A+
Sbjct: 711 VIHTGKKPYKCEECGKAFSQSSSLRKHEI----------IHSGEKPYKCEECGKAFKWLS 760
Query: 900 LLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHY 959
L H++ +P KC C + F + LR+H H G K Y
Sbjct: 761 KLTVHKVIHTAEKP----------------CKCEECGKAFKHFSALRKHKIIHTG-KKPY 803
Query: 960 MCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTG 1019
C CG+ F TL +HK+ H+ K QS H H +
Sbjct: 804 KCEECGKAFNDSSTLMKHKIIHTGKKPYKCAECGKAFKQS-----SHLTRHKAIHTGEKP 858
Query: 1020 FRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDL 1079
++C C + ++ LK H H + +KLYKC C+K F + L
Sbjct: 859 YKCEECGKDFNNSSTLKKHKLIHTR----------------EKLYKCEECVKAFNNFSAL 902
Query: 1080 VK---LDVNGLPYGLCAGC-MARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDL 1135
+K + PY C C A + ++ ++PC +C EC F+ L
Sbjct: 903 MKHKIIHTGEKPY-KCEECGKAFKWSSKLTEHKVIHTGEKPC---KCEECDKAFKHFSAL 958
Query: 1136 ESHMQVDHRDLTPETSGPRKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEG 1195
H +V H KK YQC +C F N + H H E+
Sbjct: 959 RKH-KVIHTG-------------------KKPYQCDECGKAFNNSSTLTKHKIIHTGEK- 997
Query: 1196 INHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQE 1255
++C+ C + F + L H I HS E +KC C F Q++ L +H +H E
Sbjct: 998 -PYKCEECGKAFSQSSILTKHKIIHSVE---KPYKCEECGKAFNQSSHLTRH-KTIHTGE 1052
Query: 1256 DKIYDCSQCPQKFFFQTELQNH 1277
K Y C +C + F + L H
Sbjct: 1053 -KPYKCEECGKAFIQCSYLIRH 1073
Score = 255 bits (652), Expect = 2e-67
Identities = 269/1148 (23%), Positives = 430/1148 (37%), Gaps = 187/1148 (16%)
Query: 138 YPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCH 197
Y C+ K+F S L +H+ IH++ P+K C FK + +H ++HTG+ + C
Sbjct: 75 YKCEERGKAFKSFSTLTKHKIIHTEDKPYKYKKCGNAFKFSSTFTKHKRIHTGETPFRCE 134
Query: 198 ECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEKE 257
EC AF++S +L H + H+ K +KC C + F +S+ +H H K
Sbjct: 135 ECGKAFNQSSNLTDHKRIHTGEKTYKCEECGKAFKGSSNFNAHKVIHTAEKP-------- 186
Query: 258 AKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQA 317
+ C+ C TF+ L KH + + K + C + F +TL H
Sbjct: 187 -----YKCEDCGKTFNHFSALRKHKIIHTGKKPYKRE----ECGKAFSQSSTLRKHEIIH 237
Query: 318 HANQKHKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDSSAS 377
+ +KC C + F + H H + P
Sbjct: 238 TGEKPYKCEECGKAFKWSSKLTVHKVVH----------------------TGEKPYKCEE 275
Query: 378 VERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHADKP 437
+ + STLK + K+ G K Y C C K FNS + L H K IH
Sbjct: 276 CGKAFSQFSTLK----KHKIIHTG----KKPYKCEECGKA-FNSSSTLMKH-KIIHTG-- 323
Query: 438 QQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINSLQE 497
++ + C+ C + +L H + +H + C C + F + L+
Sbjct: 324 EKPYKCEECGKAFRQSSHLTRH-KAIHTGE----------KPYKCEECGKAFNHFSDLRR 372
Query: 498 HIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPTQ 557
H ++ H G + C +C F S+L H Q H E P
Sbjct: 373 H-KIIHTG--------KKPYKCEECGKAFSQSSTLRNH-QIIHTG------EKP------ 410
Query: 558 SFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKR 617
Y C C + + S L + K I K K+ S + + + R
Sbjct: 411 -----YKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKHKVIHT--R 463
Query: 618 QRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESL 677
++L Y C +C F+N H +H + C +C + F L
Sbjct: 464 EKL-----------YKCEECGKAFNNSSILAKHKIIHTGK--KPYKCEECGKAFRQSSHL 510
Query: 678 LQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQV 737
+H +H T Y CE C K FS L++H + Y C C + F +++
Sbjct: 511 TRHKAIH--TGEKPYKCEECGKAFSHFSALRRHKIIHTGKKPYKCEECGKAFSHFSALRR 568
Query: 738 HLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQ 797
H + H+ EK Y+C C F+ + L VH K H K KC CG++F L+
Sbjct: 569 HKII-HTGEKP-YKCEECGKAFKWSSKLTVH-KVIHTAE--KPCKCEECGKSFKHFSALR 623
Query: 798 CH--ITTHSKKYNCKFCSKAFHAIILLEKH---------LREKHCVFDAATENGTANGVP 846
H I T K Y C+ C KAF++ L KH + + C A + + V
Sbjct: 624 KHKVIHTREKLYKCEECVKAFNSFSALMKHKVIHTGEKPYKCEEC--GKAFKWSSKLTVH 681
Query: 847 PMATKKAEPADLQ--GMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNH 904
+ +P + G K+ A H+ + + Y C+ CG A++ L+ H
Sbjct: 682 KVIHTGEKPCKCEECGKAFKHFSALRKHKV----IHTGKKPYKCEECGKAFSQSSSLRKH 737
Query: 905 RLRDHNIRPGEDDGSRKKAEFI------KGSH------KCNVCSRTFFSENGLREHLQTH 952
+ +P + + K +++ K H KC C + F + LR+H H
Sbjct: 738 EIIHSGEKPYKCEECGKAFKWLSKLTVHKVIHTAEKPCKCEECGKAFKHFSALRKHKIIH 797
Query: 953 RGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPD 1012
G K Y C CG+ F TL +HK+ H+ K QS H H
Sbjct: 798 TGK-KPYKCEECGKAFNDSSTLMKHKIIHTGKKPYKCAECGKAFKQSS-----HLTRHKA 851
Query: 1013 LRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKE 1072
+ ++C C + ++ LK H H + +KLYKC C+K
Sbjct: 852 IHTGEKPYKCEECGKDFNNSSTLKKHKLIHTR----------------EKLYKCEECVKA 895
Query: 1073 FRSKQDLVK---LDVNGLPYGLCAGC-MARSANGQVGGLAPPEPADRPCAGLRCPECSVK 1128
F + L+K + PY C C A + ++ ++PC +C EC
Sbjct: 896 FNNFSALMKHKIIHTGEKPYK-CEECGKAFKWSSKLTEHKVIHTGEKPC---KCEECDKA 951
Query: 1129 FESAEDLESHMQVDHRDLTP---ETSGPRKGTQTSPVPRK------KTYQCIKCQMTFEN 1179
F+ L H +V H P + G ++ K K Y+C +C F
Sbjct: 952 FKHFSALRKH-KVIHTGKKPYQCDECGKAFNNSSTLTKHKIIHTGEKPYKCEECGKAFSQ 1010
Query: 1180 EREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFV 1239
+ H H +E+ ++C+ C + F+ + L H H+ E +KC C F+
Sbjct: 1011 SSILTKHKIIHSVEKP--YKCEECGKAFNQSSHLTRHKTIHTGEK---PYKCEECGKAFI 1065
Query: 1240 QANKLQQH 1247
Q + L +H
Sbjct: 1066 QCSYLIRH 1073
Score = 227 bits (579), Expect = 5e-59
Identities = 222/892 (24%), Positives = 327/892 (36%), Gaps = 159/892 (17%)
Query: 137 PYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 196
PY C+ C K+F + S+L RH+ IH+ + P+KC C + F H RH +HTG K Y C
Sbjct: 326 PYKCEECGKAFRQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSDLRRHKIIHTGKKPYKC 385
Query: 197 HECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNK-------- 248
EC AFS+S L+ H H+ KP+KC C + F +S L H H K
Sbjct: 386 EECGKAFSQSSTLRNHQIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECG 445
Query: 249 ---EHLAKSEKE----AKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCP 301
+H + K ++ + C+ C F+ + L KH + + K +C C
Sbjct: 446 KAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKIIH----TGKKPYKCEECG 501
Query: 302 EVFVDENTLLAHIHQAHANQKHKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVL 361
+ F + L H + +KC C + FS + H H
Sbjct: 502 KAFRQSSHLTRHKAIHTGEKPYKCEECGKAFSHFSALRRHKIIH---------------- 545
Query: 362 GSVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNS 421
T E S LR K + + Y C C K F
Sbjct: 546 ---------TGKKPYKCEECGKAFSHFSALRRHKIIHTGEKP-----YKCEECGKA-FKW 590
Query: 422 LAVLEIHLKTIH-ADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAF 480
+ L +H K IH A+KP + C+ C S L +H + +H +
Sbjct: 591 SSKLTVH-KVIHTAEKPCK---CEECGKSFKHFSALRKH-KVIHTRE----------KLY 635
Query: 481 HCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAH 540
C C + F ++L +H +V H G + C +C F S LT H + H
Sbjct: 636 KCEECVKAFNSFSALMKH-KVIHTG--------EKPYKCEECGKAFKWSSKLTVH-KVIH 685
Query: 541 CSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSK 600
K C C K KH K+ + KK
Sbjct: 686 TGEKPCK-----------------CEECG---------KAFKHFSALRKHKVIHTGKKPY 719
Query: 601 AEQSPVSSDVEVSSPKRQRLSASANSISNGE--YPCNQCDLKFSNFESFQTHLKLHLELL 658
+ + + SS ++ + I +GE Y C +C F H +H
Sbjct: 720 KCEECGKAFSQSSSLRKHEI------IHSGEKPYKCEECGKAFKWLSKLTVHKVIHTAEK 773
Query: 659 LRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFV 718
K C +C + F +L +H +H T Y CE C K F+ L KH +
Sbjct: 774 PCK--CEECGKAFKHFSALRKHKIIH--TGKKPYKCEECGKAFNDSSTLMKHKIIHTGKK 829
Query: 719 LYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPA 778
Y C C + F + H A+ H+ EK Y+C C DF + L+ KH +
Sbjct: 830 PYKCAECGKAFKQSSHLTRHKAI-HTGEKP-YKCEECGKDFNNSSTLK---KHKLIHTRE 884
Query: 779 KAHKCIFCGETFSTEVELQCH--ITTHSKKYNCKFCSKAF--------HAIILLEKHLRE 828
K +KC C + F+ L H I T K Y C+ C KAF H +I H E
Sbjct: 885 KLYKCEECVKAFNNFSALMKHKIIHTGEKPYKCEECGKAFKWSSKLTEHKVI----HTGE 940
Query: 829 KHCVF---DAATENGTANGVPPM--ATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASE 883
K C D A ++ +A + KK D G N H+ + E
Sbjct: 941 KPCKCEECDKAFKHFSALRKHKVIHTGKKPYQCDECGKAFNNSSTLTKHKI----IHTGE 996
Query: 884 PMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSEN 943
Y C+ CG A++ +L H++ +P +KC C + F +
Sbjct: 997 KPYKCEECGKAFSQSSILTKHKIIHSVEKP----------------YKCEECGKAFNQSS 1040
Query: 944 GLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKM 995
L H H G K Y C CG+ F L HK H++ T ++ K+
Sbjct: 1041 HLTRHKTIHTGE-KPYKCEECGKAFIQCSYLIRHKTIHTREKPTNVKKVPKL 1091
Score = 191 bits (484), Expect = 5e-48
Identities = 209/879 (23%), Positives = 322/879 (36%), Gaps = 158/879 (17%)
Query: 64 ESIYTCDHCQQDFESLADLTDHRAHRCPGDGDDDPQLSWVASSPSSKDVASPTQMIGDGC 123
E Y C+ C + F +DL R H+ G + + S Q+I G
Sbjct: 352 EKPYKCEECGKAFNHFSDL---RRHKIIHTGKKPYKCEECGKAFSQSSTLRNHQIIHTGE 408
Query: 124 DLGLGEEEGG---------------TG-LPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFK 167
EE G TG P C+ C K+F S L++H+ IH+ + +K
Sbjct: 409 KPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKHKVIHTREKLYK 468
Query: 168 CTYCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVC 227
C C + F + +H +HTG K Y C EC AF +S HL H H+ KP+KC C
Sbjct: 469 CEECGKAFNNSSILAKHKIIHTGKKPYKCEECGKAFRQSSHLTRHKAIHTGEKPYKCEEC 528
Query: 228 KRGFSSTSSLQSHMQAHKKNKEHLAKSEKEA---------------KKDDFMCDYCEDTF 272
+ FS S+L+ H H K + + +A + + C+ C F
Sbjct: 529 GKAFSHFSALRRHKIIHTGKKPYKCEECGKAFSHFSALRRHKIIHTGEKPYKCEECGKAF 588
Query: 273 SQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQAHANQK-HKCPMCPEQ 331
+ +L H + + + +C C + F + L H H +K +KC C +
Sbjct: 589 KWSSKLTVHKVIH----TAEKPCKCEECGKSFKHFSALRKH-KVIHTREKLYKCEECVKA 643
Query: 332 FSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSA--------TPDSSASVERGST 383
F+S + H H + G SS T + E
Sbjct: 644 FNSFSALMKHKVIH-----TGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGK 698
Query: 384 PDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTC 443
LR K + K Y C C K F+ + L H + IH+ ++ + C
Sbjct: 699 AFKHFSALRKHKVIHTG-----KKPYKCEECGKA-FSQSSSLRKH-EIIHSG--EKPYKC 749
Query: 444 QICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSH 503
+ C + L L H + +H C C + F ++L++H ++ H
Sbjct: 750 EECGKAFKWLSKLTVH-KVIHTAE----------KPCKCEECGKAFKHFSALRKH-KIIH 797
Query: 504 CGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVY 563
G + C +C F S+L +H K+ +P Y
Sbjct: 798 --------TGKKPYKCEECGKAFNDSSTLMKH-----------KIIHTGKKP-------Y 831
Query: 564 SCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSP-KRQRLSA 622
C C G K + H+ HK I H+ + + D SS K+ +L
Sbjct: 832 KCAEC------GKAFKQSSHL-TRHKAI---HTGEKPYKCEECGKDFNNSSTLKKHKLIH 881
Query: 623 SANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLT 682
+ + Y C +C F+NF + H +H + C +C + F L +H
Sbjct: 882 TREKL----YKCEECVKAFNNFSALMKHKIIHTG--EKPYKCEECGKAFKWSSKLTEHKV 935
Query: 683 VHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVK 742
+H T CE CDK F L+KH + Y C C + F++ ++ H +
Sbjct: 936 IH--TGEKPCKCEECDKAFKHFSALRKHKVIHTGKKPYQCDECGKAFNNSSTLTKHKII- 992
Query: 743 HSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHITT 802
H+ EK Y+C C F + + L KH + + K +KC CG+ F+ L H T
Sbjct: 993 HTGEKP-YKCEECGKAFSQSSIL---TKHKIIHSVEKPYKCEECGKAFNQSSHLTRHKTI 1048
Query: 803 HS--KKYNCKFCSKAFHAIILLEK----HLREKHCVFDAATENGTANGVPPMATKKAEPA 856
H+ K Y C+ C KAF L + H REK P KK
Sbjct: 1049 HTGEKPYKCEECGKAFIQCSYLIRHKTIHTREK-----------------PTNVKKVP-- 1089
Query: 857 DLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAY 895
LL NP H + + E Y C+ C A+
Sbjct: 1090 ----KLLSNP-----HTLLDKTIHTGEKPYKCEECAKAF 1119
Score = 180 bits (457), Expect = 7e-45
Identities = 235/1050 (22%), Positives = 379/1050 (36%), Gaps = 186/1050 (17%)
Query: 244 HKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEV 303
HK+ L + ++ F C+ F + K RH ++K +CI C +
Sbjct: 2 HKEGYNKLNQCRTATQRKIFQCNKHMKVFHKYSNRNK---VRH---TKKKTFKCIKCSKS 55
Query: 304 FVDENTLLAHIHQAHANQK-HKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLG 362
F + L+ H + H Q +KC + F S + H H + + +
Sbjct: 56 FFMLSCLIRH-KRIHIRQNIYKCEERGKAFKSFSTLTKHKIIHTEDKPYKYKKCGN---- 110
Query: 363 SVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSL 422
A S+T + G TP + C C K FN
Sbjct: 111 --AFKFSSTFTKHKRIHTGETP------------------------FRCEECGKA-FNQS 143
Query: 423 AVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHC 482
+ L H K IH ++++ C+ C + N N H + +H + C
Sbjct: 144 SNLTDH-KRIHTG--EKTYKCEECGKAFKGSSNFNAH-KVIHTAE----------KPYKC 189
Query: 483 NYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCS 542
C + F ++L++H ++ H G + +C F S+L +H + H
Sbjct: 190 EDCGKTFNHFSALRKH-KIIHTGKKPYKRE--------ECGKAFSQSSTLRKH-EIIHTG 239
Query: 543 VGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAE 602
E P Y C C + + S L + K + K K+ ++
Sbjct: 240 ------EKP-----------YKCEECGKAFKWSSKLTVHKVVHTGEKPYKCEECGKAFSQ 282
Query: 603 QSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQ 662
S + + + K+ Y C +C F++ + H +H +
Sbjct: 283 FSTLKKHKIIHTGKKP-------------YKCEECGKAFNSSSTLMKHKIIHTGE--KPY 327
Query: 663 ACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHC 722
C +C + F L +H +H T Y CE C K F+ DL++H + Y C
Sbjct: 328 KCEECGKAFRQSSHLTRHKAIH--TGEKPYKCEECGKAFNHFSDLRRHKIIHTGKKPYKC 385
Query: 723 TLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHK 782
C + F +++ H + H+ EK Y+C C F+ + L VH K H G K K
Sbjct: 386 EECGKAFSQSSTLRNHQII-HTGEKP-YKCEECGKAFKWSSKLTVH-KVIHTGE--KPCK 440
Query: 783 CIFCGETFSTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENG 840
C CG+ F L+ H I T K Y C+ C KAF+ +L KH
Sbjct: 441 CEECGKAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKH-------------KI 487
Query: 841 TANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVL 900
G P ++ A Q +SH + E Y C+ CG A++
Sbjct: 488 IHTGKKPYKCEECGKAFRQ----------SSHLTRHKAIHTGEKPYKCEECGKAFSHFSA 537
Query: 901 LQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYM 960
L+ H++ +P +KC C + F + LR H H G K Y
Sbjct: 538 LRRHKIIHTGKKP----------------YKCEECGKAFSHFSALRRHKIIHTGE-KPYK 580
Query: 961 CPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGF 1020
C CG+ F LT HKV H+ C C + +H +H R L +
Sbjct: 581 CEECGKAFKWSSKLTVHKVIHTAEKPC-KCEECGKSFKHFSALRKHKVIHT--REKL--Y 635
Query: 1021 RCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFR--SKQD 1078
+C C++ S L H H +K YKC C K F+ SK
Sbjct: 636 KCEECVKAFNSFSALMKHKVIHTG----------------EKPYKCEECGKAFKWSSKLT 679
Query: 1079 LVKLDVNGLPYGLCAGCMARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESH 1138
+ K+ G C C A L + +C EC F + L H
Sbjct: 680 VHKVIHTGEKPCKCEEC--GKAFKHFSALRKHKVIHTGKKPYKCEECGKAFSQSSSLRKH 737
Query: 1139 MQVDHRDLTP----ETSGPRKGTQTSPVPR-----KKTYQCIKCQMTFENEREIQIHVAN 1189
++ H P E K V + +K +C +C F++ ++ H
Sbjct: 738 -EIIHSGEKPYKCEECGKAFKWLSKLTVHKVIHTAEKPCKCEECGKAFKHFSALRKHKII 796
Query: 1190 HMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIF 1249
H ++ ++C+ C + F+ + L+ H I H+ + +KC C F Q++ L +H
Sbjct: 797 HTGKKP--YKCEECGKAFNDSSTLMKHKIIHTGKK---PYKCAECGKAFKQSSHLTRHK- 850
Query: 1250 AVHGQEDKIYDCSQCPQKFFFQTELQNHTM 1279
A+H E K Y C +C + F + L+ H +
Sbjct: 851 AIHTGE-KPYKCEECGKDFNNSSTLKKHKL 879
Score = 145 bits (367), Expect = 2e-34
Identities = 152/663 (22%), Positives = 235/663 (35%), Gaps = 94/663 (14%)
Query: 636 QCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCE 695
QC+ F + K+ + C +C + F L++H +H Y CE
Sbjct: 22 QCNKHMKVFHKYSNRNKVR-HTKKKTFKCIKCSKSFFMLSCLIRHKRIHIRQNI--YKCE 78
Query: 696 SCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTAC 755
K F S L KH + Y C F + H + H+ E +RC C
Sbjct: 79 ERGKAFKSFSTLTKHKIIHTEDKPYKYKKCGNAFKFSSTFTKHKRI-HTGETP-FRCEEC 136
Query: 756 NWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHITTHS--KKYNCKFCS 813
F + ++L H K H G K +KC CG+ F H H+ K Y C+ C
Sbjct: 137 GKAFNQSSNLTDH-KRIHTGE--KTYKCEECGKAFKGSSNFNAHKVIHTAEKPYKCEDCG 193
Query: 814 KAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAPNSHE 873
K F+ L KH G P ++ A Q L+ E
Sbjct: 194 KTFNHFSALRKH-------------KIIHTGKKPYKREECGKAFSQSSTLRKHEI----- 235
Query: 874 ASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCN 933
+ E Y C+ CG A+ L H++ +P +KC
Sbjct: 236 -----IHTGEKPYKCEECGKAFKWSSKLTVHKVVHTGEKP----------------YKCE 274
Query: 934 VCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRIC 993
C + F + L++H H G K Y C CG+ F S TL +HK+ H+ C C
Sbjct: 275 ECGKAFSQFSTLKKHKIIHTGK-KPYKCEECGKAFNSSSTLMKHKIIHTGE-KPYKCEEC 332
Query: 994 KMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAAS 1053
+ H +H + ++C C + +L+ H H K
Sbjct: 333 GKAFRQSSHLTRHKAIHTGEK----PYKCEECGKAFNHFSDLRRHKIIHTGK-------- 380
Query: 1054 SPNGQGLQKLYKCALCLKEFRSKQDLVK---LDVNGLPYGLCAGC-MARSANGQVGGLAP 1109
K YKC C K F L + PY C C A + ++
Sbjct: 381 --------KPYKCEECGKAFSQSSTLRNHQIIHTGEKPY-KCEECGKAFKWSSKLTVHKV 431
Query: 1110 PEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGPRKGTQTSPV------- 1162
++PC +C EC F+ L H + R+ + K S +
Sbjct: 432 IHTGEKPC---KCEECGKAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKII 488
Query: 1163 -PRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHS 1221
KK Y+C +C F + H A H E+ ++C+ C + F + L H I H+
Sbjct: 489 HTGKKPYKCEECGKAFRQSSHLTRHKAIHTGEK--PYKCEECGKAFSHFSALRRHKIIHT 546
Query: 1222 FEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNHTMSQ 1281
+ +KC C F + L++H G +K Y C +C + F + ++L H +
Sbjct: 547 GK---KPYKCEECGKAFSHFSALRRHKIIHTG--EKPYKCEECGKAFKWSSKLTVHKVIH 601
Query: 1282 HAQ 1284
A+
Sbjct: 602 TAE 604
>gi|239751718 PREDICTED: similar to hCG1773661 [Homo sapiens]
Length = 1119
Score = 258 bits (659), Expect = 3e-68
Identities = 272/1162 (23%), Positives = 426/1162 (36%), Gaps = 211/1162 (18%)
Query: 137 PYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 196
PY + C +F S +H++IH+ + PF+C C + F + H ++HTG+K Y C
Sbjct: 102 PYKYKKCGNAFKFSSTFTKHKRIHTGETPFRCEECGKAFNQSSNLTDHKRIHTGEKTYKC 161
Query: 197 HECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEK 256
EC AF S + H H++ KP+KC C + F+ S+L+ H H K +
Sbjct: 162 EECGKAFKGSSNFNAHKVIHTAEKPYKCEDCGKTFNHFSALRKHKIIHTGKKPY------ 215
Query: 257 EAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQ 316
K+++ C FSQ+ L KH + + + +C C + F + L H
Sbjct: 216 --KREE-----CGKAFSQSSTLRKHEIIH----TGEKPYKCEECGKAFKWSSKLTVHKVV 264
Query: 317 AHANQKHKCPMCPEQFSSVEGVYCHLDSH--RQPDSSNHSVSPDPVLGSVASMSSATPDS 374
+ +KC C + FS + H H ++P A SS+T
Sbjct: 265 HTGEKPYKCEECGKAFSQFSTLKKHKIIHTGKKPYKCEEC--------GKAFNSSSTLMK 316
Query: 375 SASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHA 434
+ G P Y C C K F + L H K IH
Sbjct: 317 HKIIHTGEKP------------------------YKCEECGKA-FRQSSHLTRH-KAIHT 350
Query: 435 DKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINS 494
++ + C+ C + +L H + +H + C C + F+ ++
Sbjct: 351 G--EKPYKCEECGKAFNHFSDLRRH-KIIHTGK----------KPYKCEECGKAFSQSST 397
Query: 495 LQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEH---------IQQAHCSVG- 544
L+ H ++ H G + C +C F S LT H + C
Sbjct: 398 LRNH-QIIH--------TGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAF 448
Query: 545 ---SAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKA 601
SA + V+ + ++Y C C + SIL K I K K+
Sbjct: 449 KHFSALRKHKVIHTRE---KLYKCEECGKAFNNSSILAKHKIIHTGKKPYKCEECGKAFR 505
Query: 602 EQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRK 661
+ S ++ + + ++ Y C +C FS+F + + H +H +
Sbjct: 506 QSSHLTRHKAIHTGEK-------------PYKCEECGKAFSHFSALRRHKIIHTG--KKP 550
Query: 662 QACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYH 721
C +C + F +L +H +H T Y CE C K F L H +
Sbjct: 551 YKCEECGKAFSHFSALRRHKIIH--TGEKPYKCEECGKAFKWSSKLTVHKVIHTAEKPCK 608
Query: 722 CTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAH 781
C C + F +++ H + H+ E K+Y+C C F + L +KH + K +
Sbjct: 609 CEECGKSFKHFSALRKHKVI-HTRE-KLYKCEECVKAFNSFSAL---MKHKVIHTGEKPY 663
Query: 782 KCIFCGETFSTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFDAATEN 839
KC CG+ F +L H I T K C+ C KAF L KH
Sbjct: 664 KCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKH-------------K 710
Query: 840 GTANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEV 899
G P ++ A Q L+ E + + E Y C+ CG A+
Sbjct: 711 VIHTGKKPYKCEECGKAFSQSSSLRKHEI----------IHSGEKPYKCEECGKAFKWLS 760
Query: 900 LLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHY 959
L H++ +P KC C + F + LR+H H G K Y
Sbjct: 761 KLTVHKVIHTAEKP----------------CKCEECGKAFKHFSALRKHKIIHTG-KKPY 803
Query: 960 MCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTG 1019
C CG+ F TL +HK+ H+ K QS H H +
Sbjct: 804 KCEECGKAFNDSSTLMKHKIIHTGKKPYKCAECGKAFKQS-----SHLTRHKAIHTGEKP 858
Query: 1020 FRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDL 1079
++C C + ++ LK H H + +KLYKC C+K F + L
Sbjct: 859 YKCEECGKDFNNSSTLKKHKLIHTR----------------EKLYKCEECVKAFNNFSAL 902
Query: 1080 VK---LDVNGLPYGLCAGC-MARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDL 1135
+K + PY C C A + ++ ++PC +C EC F+ L
Sbjct: 903 MKHKIIHTGEKPY-KCEECGKAFKWSSKLTEHKVIHTGEKPC---KCEECDKAFKHFSAL 958
Query: 1136 ESHMQVDHRDLTPETSGPRKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEG 1195
H +V H KK YQC +C F N + H H E+
Sbjct: 959 RKH-KVIHTG-------------------KKPYQCDECGKAFNNSSTLTKHKIIHTGEK- 997
Query: 1196 INHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQE 1255
++C+ C + F + L H I HS E +KC C F Q++ L +H +H E
Sbjct: 998 -PYKCEECGKAFSQSSILTKHKIIHSVE---KPYKCEECGKAFNQSSHLTRH-KTIHTGE 1052
Query: 1256 DKIYDCSQCPQKFFFQTELQNH 1277
K Y C +C + F + L H
Sbjct: 1053 -KPYKCEECGKAFIQCSYLIRH 1073
Score = 255 bits (652), Expect = 2e-67
Identities = 269/1148 (23%), Positives = 430/1148 (37%), Gaps = 187/1148 (16%)
Query: 138 YPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCH 197
Y C+ K+F S L +H+ IH++ P+K C FK + +H ++HTG+ + C
Sbjct: 75 YKCEERGKAFKSFSTLTKHKIIHTEDKPYKYKKCGNAFKFSSTFTKHKRIHTGETPFRCE 134
Query: 198 ECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEKE 257
EC AF++S +L H + H+ K +KC C + F +S+ +H H K
Sbjct: 135 ECGKAFNQSSNLTDHKRIHTGEKTYKCEECGKAFKGSSNFNAHKVIHTAEKP-------- 186
Query: 258 AKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQA 317
+ C+ C TF+ L KH + + K + C + F +TL H
Sbjct: 187 -----YKCEDCGKTFNHFSALRKHKIIHTGKKPYKRE----ECGKAFSQSSTLRKHEIIH 237
Query: 318 HANQKHKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDSSAS 377
+ +KC C + F + H H + P
Sbjct: 238 TGEKPYKCEECGKAFKWSSKLTVHKVVH----------------------TGEKPYKCEE 275
Query: 378 VERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHADKP 437
+ + STLK + K+ G K Y C C K FNS + L H K IH
Sbjct: 276 CGKAFSQFSTLK----KHKIIHTG----KKPYKCEECGKA-FNSSSTLMKH-KIIHTG-- 323
Query: 438 QQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINSLQE 497
++ + C+ C + +L H + +H + C C + F + L+
Sbjct: 324 EKPYKCEECGKAFRQSSHLTRH-KAIHTGE----------KPYKCEECGKAFNHFSDLRR 372
Query: 498 HIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPTQ 557
H ++ H G + C +C F S+L H Q H E P
Sbjct: 373 H-KIIHTG--------KKPYKCEECGKAFSQSSTLRNH-QIIHTG------EKP------ 410
Query: 558 SFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKR 617
Y C C + + S L + K I K K+ S + + + R
Sbjct: 411 -----YKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKHKVIHT--R 463
Query: 618 QRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESL 677
++L Y C +C F+N H +H + C +C + F L
Sbjct: 464 EKL-----------YKCEECGKAFNNSSILAKHKIIHTGK--KPYKCEECGKAFRQSSHL 510
Query: 678 LQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQV 737
+H +H T Y CE C K FS L++H + Y C C + F +++
Sbjct: 511 TRHKAIH--TGEKPYKCEECGKAFSHFSALRRHKIIHTGKKPYKCEECGKAFSHFSALRR 568
Query: 738 HLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQ 797
H + H+ EK Y+C C F+ + L VH K H K KC CG++F L+
Sbjct: 569 HKII-HTGEKP-YKCEECGKAFKWSSKLTVH-KVIHTAE--KPCKCEECGKSFKHFSALR 623
Query: 798 CH--ITTHSKKYNCKFCSKAFHAIILLEKH---------LREKHCVFDAATENGTANGVP 846
H I T K Y C+ C KAF++ L KH + + C A + + V
Sbjct: 624 KHKVIHTREKLYKCEECVKAFNSFSALMKHKVIHTGEKPYKCEEC--GKAFKWSSKLTVH 681
Query: 847 PMATKKAEPADLQ--GMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNH 904
+ +P + G K+ A H+ + + Y C+ CG A++ L+ H
Sbjct: 682 KVIHTGEKPCKCEECGKAFKHFSALRKHKV----IHTGKKPYKCEECGKAFSQSSSLRKH 737
Query: 905 RLRDHNIRPGEDDGSRKKAEFI------KGSH------KCNVCSRTFFSENGLREHLQTH 952
+ +P + + K +++ K H KC C + F + LR+H H
Sbjct: 738 EIIHSGEKPYKCEECGKAFKWLSKLTVHKVIHTAEKPCKCEECGKAFKHFSALRKHKIIH 797
Query: 953 RGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPD 1012
G K Y C CG+ F TL +HK+ H+ K QS H H
Sbjct: 798 TGK-KPYKCEECGKAFNDSSTLMKHKIIHTGKKPYKCAECGKAFKQSS-----HLTRHKA 851
Query: 1013 LRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKE 1072
+ ++C C + ++ LK H H + +KLYKC C+K
Sbjct: 852 IHTGEKPYKCEECGKDFNNSSTLKKHKLIHTR----------------EKLYKCEECVKA 895
Query: 1073 FRSKQDLVK---LDVNGLPYGLCAGC-MARSANGQVGGLAPPEPADRPCAGLRCPECSVK 1128
F + L+K + PY C C A + ++ ++PC +C EC
Sbjct: 896 FNNFSALMKHKIIHTGEKPYK-CEECGKAFKWSSKLTEHKVIHTGEKPC---KCEECDKA 951
Query: 1129 FESAEDLESHMQVDHRDLTP---ETSGPRKGTQTSPVPRK------KTYQCIKCQMTFEN 1179
F+ L H +V H P + G ++ K K Y+C +C F
Sbjct: 952 FKHFSALRKH-KVIHTGKKPYQCDECGKAFNNSSTLTKHKIIHTGEKPYKCEECGKAFSQ 1010
Query: 1180 EREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFV 1239
+ H H +E+ ++C+ C + F+ + L H H+ E +KC C F+
Sbjct: 1011 SSILTKHKIIHSVEKP--YKCEECGKAFNQSSHLTRHKTIHTGEK---PYKCEECGKAFI 1065
Query: 1240 QANKLQQH 1247
Q + L +H
Sbjct: 1066 QCSYLIRH 1073
Score = 227 bits (579), Expect = 5e-59
Identities = 222/892 (24%), Positives = 327/892 (36%), Gaps = 159/892 (17%)
Query: 137 PYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 196
PY C+ C K+F + S+L RH+ IH+ + P+KC C + F H RH +HTG K Y C
Sbjct: 326 PYKCEECGKAFRQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSDLRRHKIIHTGKKPYKC 385
Query: 197 HECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNK-------- 248
EC AFS+S L+ H H+ KP+KC C + F +S L H H K
Sbjct: 386 EECGKAFSQSSTLRNHQIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECG 445
Query: 249 ---EHLAKSEKE----AKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCP 301
+H + K ++ + C+ C F+ + L KH + + K +C C
Sbjct: 446 KAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKIIH----TGKKPYKCEECG 501
Query: 302 EVFVDENTLLAHIHQAHANQKHKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVL 361
+ F + L H + +KC C + FS + H H
Sbjct: 502 KAFRQSSHLTRHKAIHTGEKPYKCEECGKAFSHFSALRRHKIIH---------------- 545
Query: 362 GSVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNS 421
T E S LR K + + Y C C K F
Sbjct: 546 ---------TGKKPYKCEECGKAFSHFSALRRHKIIHTGEKP-----YKCEECGKA-FKW 590
Query: 422 LAVLEIHLKTIH-ADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAF 480
+ L +H K IH A+KP + C+ C S L +H + +H +
Sbjct: 591 SSKLTVH-KVIHTAEKPCK---CEECGKSFKHFSALRKH-KVIHTRE----------KLY 635
Query: 481 HCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAH 540
C C + F ++L +H +V H G + C +C F S LT H + H
Sbjct: 636 KCEECVKAFNSFSALMKH-KVIHTG--------EKPYKCEECGKAFKWSSKLTVH-KVIH 685
Query: 541 CSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSK 600
K C C K KH K+ + KK
Sbjct: 686 TGEKPCK-----------------CEECG---------KAFKHFSALRKHKVIHTGKKPY 719
Query: 601 AEQSPVSSDVEVSSPKRQRLSASANSISNGE--YPCNQCDLKFSNFESFQTHLKLHLELL 658
+ + + SS ++ + I +GE Y C +C F H +H
Sbjct: 720 KCEECGKAFSQSSSLRKHEI------IHSGEKPYKCEECGKAFKWLSKLTVHKVIHTAEK 773
Query: 659 LRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFV 718
K C +C + F +L +H +H T Y CE C K F+ L KH +
Sbjct: 774 PCK--CEECGKAFKHFSALRKHKIIH--TGKKPYKCEECGKAFNDSSTLMKHKIIHTGKK 829
Query: 719 LYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPA 778
Y C C + F + H A+ H+ EK Y+C C DF + L+ KH +
Sbjct: 830 PYKCAECGKAFKQSSHLTRHKAI-HTGEKP-YKCEECGKDFNNSSTLK---KHKLIHTRE 884
Query: 779 KAHKCIFCGETFSTEVELQCH--ITTHSKKYNCKFCSKAF--------HAIILLEKHLRE 828
K +KC C + F+ L H I T K Y C+ C KAF H +I H E
Sbjct: 885 KLYKCEECVKAFNNFSALMKHKIIHTGEKPYKCEECGKAFKWSSKLTEHKVI----HTGE 940
Query: 829 KHCVF---DAATENGTANGVPPM--ATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASE 883
K C D A ++ +A + KK D G N H+ + E
Sbjct: 941 KPCKCEECDKAFKHFSALRKHKVIHTGKKPYQCDECGKAFNNSSTLTKHKI----IHTGE 996
Query: 884 PMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSEN 943
Y C+ CG A++ +L H++ +P +KC C + F +
Sbjct: 997 KPYKCEECGKAFSQSSILTKHKIIHSVEKP----------------YKCEECGKAFNQSS 1040
Query: 944 GLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKM 995
L H H G K Y C CG+ F L HK H++ T ++ K+
Sbjct: 1041 HLTRHKTIHTGE-KPYKCEECGKAFIQCSYLIRHKTIHTREKPTNVKKVPKL 1091
Score = 191 bits (484), Expect = 5e-48
Identities = 209/879 (23%), Positives = 322/879 (36%), Gaps = 158/879 (17%)
Query: 64 ESIYTCDHCQQDFESLADLTDHRAHRCPGDGDDDPQLSWVASSPSSKDVASPTQMIGDGC 123
E Y C+ C + F +DL R H+ G + + S Q+I G
Sbjct: 352 EKPYKCEECGKAFNHFSDL---RRHKIIHTGKKPYKCEECGKAFSQSSTLRNHQIIHTGE 408
Query: 124 DLGLGEEEGG---------------TG-LPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFK 167
EE G TG P C+ C K+F S L++H+ IH+ + +K
Sbjct: 409 KPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKHKVIHTREKLYK 468
Query: 168 CTYCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVC 227
C C + F + +H +HTG K Y C EC AF +S HL H H+ KP+KC C
Sbjct: 469 CEECGKAFNNSSILAKHKIIHTGKKPYKCEECGKAFRQSSHLTRHKAIHTGEKPYKCEEC 528
Query: 228 KRGFSSTSSLQSHMQAHKKNKEHLAKSEKEA---------------KKDDFMCDYCEDTF 272
+ FS S+L+ H H K + + +A + + C+ C F
Sbjct: 529 GKAFSHFSALRRHKIIHTGKKPYKCEECGKAFSHFSALRRHKIIHTGEKPYKCEECGKAF 588
Query: 273 SQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQAHANQK-HKCPMCPEQ 331
+ +L H + + + +C C + F + L H H +K +KC C +
Sbjct: 589 KWSSKLTVHKVIH----TAEKPCKCEECGKSFKHFSALRKH-KVIHTREKLYKCEECVKA 643
Query: 332 FSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSA--------TPDSSASVERGST 383
F+S + H H + G SS T + E
Sbjct: 644 FNSFSALMKHKVIH-----TGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGK 698
Query: 384 PDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTC 443
LR K + K Y C C K F+ + L H + IH+ ++ + C
Sbjct: 699 AFKHFSALRKHKVIHTG-----KKPYKCEECGKA-FSQSSSLRKH-EIIHSG--EKPYKC 749
Query: 444 QICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSH 503
+ C + L L H + +H C C + F ++L++H ++ H
Sbjct: 750 EECGKAFKWLSKLTVH-KVIHTAE----------KPCKCEECGKAFKHFSALRKH-KIIH 797
Query: 504 CGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVY 563
G + C +C F S+L +H K+ +P Y
Sbjct: 798 --------TGKKPYKCEECGKAFNDSSTLMKH-----------KIIHTGKKP-------Y 831
Query: 564 SCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSP-KRQRLSA 622
C C G K + H+ HK I H+ + + D SS K+ +L
Sbjct: 832 KCAEC------GKAFKQSSHL-TRHKAI---HTGEKPYKCEECGKDFNNSSTLKKHKLIH 881
Query: 623 SANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLT 682
+ + Y C +C F+NF + H +H + C +C + F L +H
Sbjct: 882 TREKL----YKCEECVKAFNNFSALMKHKIIHTG--EKPYKCEECGKAFKWSSKLTEHKV 935
Query: 683 VHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVK 742
+H T CE CDK F L+KH + Y C C + F++ ++ H +
Sbjct: 936 IH--TGEKPCKCEECDKAFKHFSALRKHKVIHTGKKPYQCDECGKAFNNSSTLTKHKII- 992
Query: 743 HSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHITT 802
H+ EK Y+C C F + + L KH + + K +KC CG+ F+ L H T
Sbjct: 993 HTGEKP-YKCEECGKAFSQSSIL---TKHKIIHSVEKPYKCEECGKAFNQSSHLTRHKTI 1048
Query: 803 HS--KKYNCKFCSKAFHAIILLEK----HLREKHCVFDAATENGTANGVPPMATKKAEPA 856
H+ K Y C+ C KAF L + H REK P KK
Sbjct: 1049 HTGEKPYKCEECGKAFIQCSYLIRHKTIHTREK-----------------PTNVKKVP-- 1089
Query: 857 DLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAY 895
LL NP H + + E Y C+ C A+
Sbjct: 1090 ----KLLSNP-----HTLLDKTIHTGEKPYKCEECAKAF 1119
Score = 180 bits (457), Expect = 7e-45
Identities = 235/1050 (22%), Positives = 379/1050 (36%), Gaps = 186/1050 (17%)
Query: 244 HKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEV 303
HK+ L + ++ F C+ F + K RH ++K +CI C +
Sbjct: 2 HKEGYNKLNQCRTATQRKIFQCNKHMKVFHKYSNRNK---VRH---TKKKTFKCIKCSKS 55
Query: 304 FVDENTLLAHIHQAHANQK-HKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLG 362
F + L+ H + H Q +KC + F S + H H + + +
Sbjct: 56 FFMLSCLIRH-KRIHIRQNIYKCEERGKAFKSFSTLTKHKIIHTEDKPYKYKKCGN---- 110
Query: 363 SVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSL 422
A S+T + G TP + C C K FN
Sbjct: 111 --AFKFSSTFTKHKRIHTGETP------------------------FRCEECGKA-FNQS 143
Query: 423 AVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHC 482
+ L H K IH ++++ C+ C + N N H + +H + C
Sbjct: 144 SNLTDH-KRIHTG--EKTYKCEECGKAFKGSSNFNAH-KVIHTAE----------KPYKC 189
Query: 483 NYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCS 542
C + F ++L++H ++ H G + +C F S+L +H + H
Sbjct: 190 EDCGKTFNHFSALRKH-KIIHTGKKPYKRE--------ECGKAFSQSSTLRKH-EIIHTG 239
Query: 543 VGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAE 602
E P Y C C + + S L + K + K K+ ++
Sbjct: 240 ------EKP-----------YKCEECGKAFKWSSKLTVHKVVHTGEKPYKCEECGKAFSQ 282
Query: 603 QSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQ 662
S + + + K+ Y C +C F++ + H +H +
Sbjct: 283 FSTLKKHKIIHTGKKP-------------YKCEECGKAFNSSSTLMKHKIIHTGE--KPY 327
Query: 663 ACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHC 722
C +C + F L +H +H T Y CE C K F+ DL++H + Y C
Sbjct: 328 KCEECGKAFRQSSHLTRHKAIH--TGEKPYKCEECGKAFNHFSDLRRHKIIHTGKKPYKC 385
Query: 723 TLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHK 782
C + F +++ H + H+ EK Y+C C F+ + L VH K H G K K
Sbjct: 386 EECGKAFSQSSTLRNHQII-HTGEKP-YKCEECGKAFKWSSKLTVH-KVIHTGE--KPCK 440
Query: 783 CIFCGETFSTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENG 840
C CG+ F L+ H I T K Y C+ C KAF+ +L KH
Sbjct: 441 CEECGKAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKH-------------KI 487
Query: 841 TANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVL 900
G P ++ A Q +SH + E Y C+ CG A++
Sbjct: 488 IHTGKKPYKCEECGKAFRQ----------SSHLTRHKAIHTGEKPYKCEECGKAFSHFSA 537
Query: 901 LQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYM 960
L+ H++ +P +KC C + F + LR H H G K Y
Sbjct: 538 LRRHKIIHTGKKP----------------YKCEECGKAFSHFSALRRHKIIHTGE-KPYK 580
Query: 961 CPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGF 1020
C CG+ F LT HKV H+ C C + +H +H R L +
Sbjct: 581 CEECGKAFKWSSKLTVHKVIHTAEKPC-KCEECGKSFKHFSALRKHKVIHT--REKL--Y 635
Query: 1021 RCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFR--SKQD 1078
+C C++ S L H H +K YKC C K F+ SK
Sbjct: 636 KCEECVKAFNSFSALMKHKVIHTG----------------EKPYKCEECGKAFKWSSKLT 679
Query: 1079 LVKLDVNGLPYGLCAGCMARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESH 1138
+ K+ G C C A L + +C EC F + L H
Sbjct: 680 VHKVIHTGEKPCKCEEC--GKAFKHFSALRKHKVIHTGKKPYKCEECGKAFSQSSSLRKH 737
Query: 1139 MQVDHRDLTP----ETSGPRKGTQTSPVPR-----KKTYQCIKCQMTFENEREIQIHVAN 1189
++ H P E K V + +K +C +C F++ ++ H
Sbjct: 738 -EIIHSGEKPYKCEECGKAFKWLSKLTVHKVIHTAEKPCKCEECGKAFKHFSALRKHKII 796
Query: 1190 HMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIF 1249
H ++ ++C+ C + F+ + L+ H I H+ + +KC C F Q++ L +H
Sbjct: 797 HTGKKP--YKCEECGKAFNDSSTLMKHKIIHTGKK---PYKCAECGKAFKQSSHLTRHK- 850
Query: 1250 AVHGQEDKIYDCSQCPQKFFFQTELQNHTM 1279
A+H E K Y C +C + F + L+ H +
Sbjct: 851 AIHTGE-KPYKCEECGKDFNNSSTLKKHKL 879
Score = 145 bits (367), Expect = 2e-34
Identities = 152/663 (22%), Positives = 235/663 (35%), Gaps = 94/663 (14%)
Query: 636 QCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCE 695
QC+ F + K+ + C +C + F L++H +H Y CE
Sbjct: 22 QCNKHMKVFHKYSNRNKVR-HTKKKTFKCIKCSKSFFMLSCLIRHKRIHIRQNI--YKCE 78
Query: 696 SCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTAC 755
K F S L KH + Y C F + H + H+ E +RC C
Sbjct: 79 ERGKAFKSFSTLTKHKIIHTEDKPYKYKKCGNAFKFSSTFTKHKRI-HTGETP-FRCEEC 136
Query: 756 NWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHITTHS--KKYNCKFCS 813
F + ++L H K H G K +KC CG+ F H H+ K Y C+ C
Sbjct: 137 GKAFNQSSNLTDH-KRIHTGE--KTYKCEECGKAFKGSSNFNAHKVIHTAEKPYKCEDCG 193
Query: 814 KAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAPNSHE 873
K F+ L KH G P ++ A Q L+ E
Sbjct: 194 KTFNHFSALRKH-------------KIIHTGKKPYKREECGKAFSQSSTLRKHEI----- 235
Query: 874 ASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCN 933
+ E Y C+ CG A+ L H++ +P +KC
Sbjct: 236 -----IHTGEKPYKCEECGKAFKWSSKLTVHKVVHTGEKP----------------YKCE 274
Query: 934 VCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRIC 993
C + F + L++H H G K Y C CG+ F S TL +HK+ H+ C C
Sbjct: 275 ECGKAFSQFSTLKKHKIIHTGK-KPYKCEECGKAFNSSSTLMKHKIIHTGE-KPYKCEEC 332
Query: 994 KMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAAS 1053
+ H +H + ++C C + +L+ H H K
Sbjct: 333 GKAFRQSSHLTRHKAIHTGEK----PYKCEECGKAFNHFSDLRRHKIIHTGK-------- 380
Query: 1054 SPNGQGLQKLYKCALCLKEFRSKQDLVK---LDVNGLPYGLCAGC-MARSANGQVGGLAP 1109
K YKC C K F L + PY C C A + ++
Sbjct: 381 --------KPYKCEECGKAFSQSSTLRNHQIIHTGEKPY-KCEECGKAFKWSSKLTVHKV 431
Query: 1110 PEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGPRKGTQTSPV------- 1162
++PC +C EC F+ L H + R+ + K S +
Sbjct: 432 IHTGEKPC---KCEECGKAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKII 488
Query: 1163 -PRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHS 1221
KK Y+C +C F + H A H E+ ++C+ C + F + L H I H+
Sbjct: 489 HTGKKPYKCEECGKAFRQSSHLTRHKAIHTGEK--PYKCEECGKAFSHFSALRRHKIIHT 546
Query: 1222 FEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNHTMSQ 1281
+ +KC C F + L++H G +K Y C +C + F + ++L H +
Sbjct: 547 GK---KPYKCEECGKAFSHFSALRRHKIIHTG--EKPYKCEECGKAFKWSSKLTVHKVIH 601
Query: 1282 HAQ 1284
A+
Sbjct: 602 TAE 604
>gi|239746221 PREDICTED: hypothetical protein XP_002343677 [Homo
sapiens]
Length = 1119
Score = 258 bits (659), Expect = 3e-68
Identities = 272/1162 (23%), Positives = 426/1162 (36%), Gaps = 211/1162 (18%)
Query: 137 PYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 196
PY + C +F S +H++IH+ + PF+C C + F + H ++HTG+K Y C
Sbjct: 102 PYKYKKCGNAFKFSSTFTKHKRIHTGETPFRCEECGKAFNQSSNLTDHKRIHTGEKTYKC 161
Query: 197 HECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEK 256
EC AF S + H H++ KP+KC C + F+ S+L+ H H K +
Sbjct: 162 EECGKAFKGSSNFNAHKVIHTAEKPYKCEDCGKTFNHFSALRKHKIIHTGKKPY------ 215
Query: 257 EAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQ 316
K+++ C FSQ+ L KH + + + +C C + F + L H
Sbjct: 216 --KREE-----CGKAFSQSSTLRKHEIIH----TGEKPYKCEECGKAFKWSSKLTVHKVV 264
Query: 317 AHANQKHKCPMCPEQFSSVEGVYCHLDSH--RQPDSSNHSVSPDPVLGSVASMSSATPDS 374
+ +KC C + FS + H H ++P A SS+T
Sbjct: 265 HTGEKPYKCEECGKAFSQFSTLKKHKIIHTGKKPYKCEEC--------GKAFNSSSTLMK 316
Query: 375 SASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHA 434
+ G P Y C C K F + L H K IH
Sbjct: 317 HKIIHTGEKP------------------------YKCEECGKA-FRQSSHLTRH-KAIHT 350
Query: 435 DKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINS 494
++ + C+ C + +L H + +H + C C + F+ ++
Sbjct: 351 G--EKPYKCEECGKAFNHFSDLRRH-KIIHTGK----------KPYKCEECGKAFSQSST 397
Query: 495 LQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEH---------IQQAHCSVG- 544
L+ H ++ H G + C +C F S LT H + C
Sbjct: 398 LRNH-QIIH--------TGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAF 448
Query: 545 ---SAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKA 601
SA + V+ + ++Y C C + SIL K I K K+
Sbjct: 449 KHFSALRKHKVIHTRE---KLYKCEECGKAFNNSSILAKHKIIHTGKKPYKCEECGKAFR 505
Query: 602 EQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRK 661
+ S ++ + + ++ Y C +C FS+F + + H +H +
Sbjct: 506 QSSHLTRHKAIHTGEK-------------PYKCEECGKAFSHFSALRRHKIIHTG--KKP 550
Query: 662 QACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYH 721
C +C + F +L +H +H T Y CE C K F L H +
Sbjct: 551 YKCEECGKAFSHFSALRRHKIIH--TGEKPYKCEECGKAFKWSSKLTVHKVIHTAEKPCK 608
Query: 722 CTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAH 781
C C + F +++ H + H+ E K+Y+C C F + L +KH + K +
Sbjct: 609 CEECGKSFKHFSALRKHKVI-HTRE-KLYKCEECVKAFNSFSAL---MKHKVIHTGEKPY 663
Query: 782 KCIFCGETFSTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFDAATEN 839
KC CG+ F +L H I T K C+ C KAF L KH
Sbjct: 664 KCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKH-------------K 710
Query: 840 GTANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEV 899
G P ++ A Q L+ E + + E Y C+ CG A+
Sbjct: 711 VIHTGKKPYKCEECGKAFSQSSSLRKHEI----------IHSGEKPYKCEECGKAFKWLS 760
Query: 900 LLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHY 959
L H++ +P KC C + F + LR+H H G K Y
Sbjct: 761 KLTVHKVIHTAEKP----------------CKCEECGKAFKHFSALRKHKIIHTG-KKPY 803
Query: 960 MCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTG 1019
C CG+ F TL +HK+ H+ K QS H H +
Sbjct: 804 KCEECGKAFNDSSTLMKHKIIHTGKKPYKCAECGKAFKQS-----SHLTRHKAIHTGEKP 858
Query: 1020 FRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDL 1079
++C C + ++ LK H H + +KLYKC C+K F + L
Sbjct: 859 YKCEECGKDFNNSSTLKKHKLIHTR----------------EKLYKCEECVKAFNNFSAL 902
Query: 1080 VK---LDVNGLPYGLCAGC-MARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDL 1135
+K + PY C C A + ++ ++PC +C EC F+ L
Sbjct: 903 MKHKIIHTGEKPY-KCEECGKAFKWSSKLTEHKVIHTGEKPC---KCEECDKAFKHFSAL 958
Query: 1136 ESHMQVDHRDLTPETSGPRKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEG 1195
H +V H KK YQC +C F N + H H E+
Sbjct: 959 RKH-KVIHTG-------------------KKPYQCDECGKAFNNSSTLTKHKIIHTGEK- 997
Query: 1196 INHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQE 1255
++C+ C + F + L H I HS E +KC C F Q++ L +H +H E
Sbjct: 998 -PYKCEECGKAFSQSSILTKHKIIHSVE---KPYKCEECGKAFNQSSHLTRH-KTIHTGE 1052
Query: 1256 DKIYDCSQCPQKFFFQTELQNH 1277
K Y C +C + F + L H
Sbjct: 1053 -KPYKCEECGKAFIQCSYLIRH 1073
Score = 255 bits (652), Expect = 2e-67
Identities = 269/1148 (23%), Positives = 430/1148 (37%), Gaps = 187/1148 (16%)
Query: 138 YPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCH 197
Y C+ K+F S L +H+ IH++ P+K C FK + +H ++HTG+ + C
Sbjct: 75 YKCEERGKAFKSFSTLTKHKIIHTEDKPYKYKKCGNAFKFSSTFTKHKRIHTGETPFRCE 134
Query: 198 ECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEKE 257
EC AF++S +L H + H+ K +KC C + F +S+ +H H K
Sbjct: 135 ECGKAFNQSSNLTDHKRIHTGEKTYKCEECGKAFKGSSNFNAHKVIHTAEKP-------- 186
Query: 258 AKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQA 317
+ C+ C TF+ L KH + + K + C + F +TL H
Sbjct: 187 -----YKCEDCGKTFNHFSALRKHKIIHTGKKPYKRE----ECGKAFSQSSTLRKHEIIH 237
Query: 318 HANQKHKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDSSAS 377
+ +KC C + F + H H + P
Sbjct: 238 TGEKPYKCEECGKAFKWSSKLTVHKVVH----------------------TGEKPYKCEE 275
Query: 378 VERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHADKP 437
+ + STLK + K+ G K Y C C K FNS + L H K IH
Sbjct: 276 CGKAFSQFSTLK----KHKIIHTG----KKPYKCEECGKA-FNSSSTLMKH-KIIHTG-- 323
Query: 438 QQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINSLQE 497
++ + C+ C + +L H + +H + C C + F + L+
Sbjct: 324 EKPYKCEECGKAFRQSSHLTRH-KAIHTGE----------KPYKCEECGKAFNHFSDLRR 372
Query: 498 HIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPTQ 557
H ++ H G + C +C F S+L H Q H E P
Sbjct: 373 H-KIIHTG--------KKPYKCEECGKAFSQSSTLRNH-QIIHTG------EKP------ 410
Query: 558 SFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKR 617
Y C C + + S L + K I K K+ S + + + R
Sbjct: 411 -----YKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKHKVIHT--R 463
Query: 618 QRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESL 677
++L Y C +C F+N H +H + C +C + F L
Sbjct: 464 EKL-----------YKCEECGKAFNNSSILAKHKIIHTGK--KPYKCEECGKAFRQSSHL 510
Query: 678 LQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQV 737
+H +H T Y CE C K FS L++H + Y C C + F +++
Sbjct: 511 TRHKAIH--TGEKPYKCEECGKAFSHFSALRRHKIIHTGKKPYKCEECGKAFSHFSALRR 568
Query: 738 HLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQ 797
H + H+ EK Y+C C F+ + L VH K H K KC CG++F L+
Sbjct: 569 HKII-HTGEKP-YKCEECGKAFKWSSKLTVH-KVIHTAE--KPCKCEECGKSFKHFSALR 623
Query: 798 CH--ITTHSKKYNCKFCSKAFHAIILLEKH---------LREKHCVFDAATENGTANGVP 846
H I T K Y C+ C KAF++ L KH + + C A + + V
Sbjct: 624 KHKVIHTREKLYKCEECVKAFNSFSALMKHKVIHTGEKPYKCEEC--GKAFKWSSKLTVH 681
Query: 847 PMATKKAEPADLQ--GMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNH 904
+ +P + G K+ A H+ + + Y C+ CG A++ L+ H
Sbjct: 682 KVIHTGEKPCKCEECGKAFKHFSALRKHKV----IHTGKKPYKCEECGKAFSQSSSLRKH 737
Query: 905 RLRDHNIRPGEDDGSRKKAEFI------KGSH------KCNVCSRTFFSENGLREHLQTH 952
+ +P + + K +++ K H KC C + F + LR+H H
Sbjct: 738 EIIHSGEKPYKCEECGKAFKWLSKLTVHKVIHTAEKPCKCEECGKAFKHFSALRKHKIIH 797
Query: 953 RGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPD 1012
G K Y C CG+ F TL +HK+ H+ K QS H H
Sbjct: 798 TGK-KPYKCEECGKAFNDSSTLMKHKIIHTGKKPYKCAECGKAFKQSS-----HLTRHKA 851
Query: 1013 LRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKE 1072
+ ++C C + ++ LK H H + +KLYKC C+K
Sbjct: 852 IHTGEKPYKCEECGKDFNNSSTLKKHKLIHTR----------------EKLYKCEECVKA 895
Query: 1073 FRSKQDLVK---LDVNGLPYGLCAGC-MARSANGQVGGLAPPEPADRPCAGLRCPECSVK 1128
F + L+K + PY C C A + ++ ++PC +C EC
Sbjct: 896 FNNFSALMKHKIIHTGEKPYK-CEECGKAFKWSSKLTEHKVIHTGEKPC---KCEECDKA 951
Query: 1129 FESAEDLESHMQVDHRDLTP---ETSGPRKGTQTSPVPRK------KTYQCIKCQMTFEN 1179
F+ L H +V H P + G ++ K K Y+C +C F
Sbjct: 952 FKHFSALRKH-KVIHTGKKPYQCDECGKAFNNSSTLTKHKIIHTGEKPYKCEECGKAFSQ 1010
Query: 1180 EREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFV 1239
+ H H +E+ ++C+ C + F+ + L H H+ E +KC C F+
Sbjct: 1011 SSILTKHKIIHSVEKP--YKCEECGKAFNQSSHLTRHKTIHTGEK---PYKCEECGKAFI 1065
Query: 1240 QANKLQQH 1247
Q + L +H
Sbjct: 1066 QCSYLIRH 1073
Score = 227 bits (579), Expect = 5e-59
Identities = 222/892 (24%), Positives = 327/892 (36%), Gaps = 159/892 (17%)
Query: 137 PYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 196
PY C+ C K+F + S+L RH+ IH+ + P+KC C + F H RH +HTG K Y C
Sbjct: 326 PYKCEECGKAFRQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSDLRRHKIIHTGKKPYKC 385
Query: 197 HECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNK-------- 248
EC AFS+S L+ H H+ KP+KC C + F +S L H H K
Sbjct: 386 EECGKAFSQSSTLRNHQIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECG 445
Query: 249 ---EHLAKSEKE----AKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCP 301
+H + K ++ + C+ C F+ + L KH + + K +C C
Sbjct: 446 KAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKIIH----TGKKPYKCEECG 501
Query: 302 EVFVDENTLLAHIHQAHANQKHKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVL 361
+ F + L H + +KC C + FS + H H
Sbjct: 502 KAFRQSSHLTRHKAIHTGEKPYKCEECGKAFSHFSALRRHKIIH---------------- 545
Query: 362 GSVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNS 421
T E S LR K + + Y C C K F
Sbjct: 546 ---------TGKKPYKCEECGKAFSHFSALRRHKIIHTGEKP-----YKCEECGKA-FKW 590
Query: 422 LAVLEIHLKTIH-ADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAF 480
+ L +H K IH A+KP + C+ C S L +H + +H +
Sbjct: 591 SSKLTVH-KVIHTAEKPCK---CEECGKSFKHFSALRKH-KVIHTRE----------KLY 635
Query: 481 HCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAH 540
C C + F ++L +H +V H G + C +C F S LT H + H
Sbjct: 636 KCEECVKAFNSFSALMKH-KVIHTG--------EKPYKCEECGKAFKWSSKLTVH-KVIH 685
Query: 541 CSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSK 600
K C C K KH K+ + KK
Sbjct: 686 TGEKPCK-----------------CEECG---------KAFKHFSALRKHKVIHTGKKPY 719
Query: 601 AEQSPVSSDVEVSSPKRQRLSASANSISNGE--YPCNQCDLKFSNFESFQTHLKLHLELL 658
+ + + SS ++ + I +GE Y C +C F H +H
Sbjct: 720 KCEECGKAFSQSSSLRKHEI------IHSGEKPYKCEECGKAFKWLSKLTVHKVIHTAEK 773
Query: 659 LRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFV 718
K C +C + F +L +H +H T Y CE C K F+ L KH +
Sbjct: 774 PCK--CEECGKAFKHFSALRKHKIIH--TGKKPYKCEECGKAFNDSSTLMKHKIIHTGKK 829
Query: 719 LYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPA 778
Y C C + F + H A+ H+ EK Y+C C DF + L+ KH +
Sbjct: 830 PYKCAECGKAFKQSSHLTRHKAI-HTGEKP-YKCEECGKDFNNSSTLK---KHKLIHTRE 884
Query: 779 KAHKCIFCGETFSTEVELQCH--ITTHSKKYNCKFCSKAF--------HAIILLEKHLRE 828
K +KC C + F+ L H I T K Y C+ C KAF H +I H E
Sbjct: 885 KLYKCEECVKAFNNFSALMKHKIIHTGEKPYKCEECGKAFKWSSKLTEHKVI----HTGE 940
Query: 829 KHCVF---DAATENGTANGVPPM--ATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASE 883
K C D A ++ +A + KK D G N H+ + E
Sbjct: 941 KPCKCEECDKAFKHFSALRKHKVIHTGKKPYQCDECGKAFNNSSTLTKHKI----IHTGE 996
Query: 884 PMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSEN 943
Y C+ CG A++ +L H++ +P +KC C + F +
Sbjct: 997 KPYKCEECGKAFSQSSILTKHKIIHSVEKP----------------YKCEECGKAFNQSS 1040
Query: 944 GLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKM 995
L H H G K Y C CG+ F L HK H++ T ++ K+
Sbjct: 1041 HLTRHKTIHTGE-KPYKCEECGKAFIQCSYLIRHKTIHTREKPTNVKKVPKL 1091
Score = 191 bits (484), Expect = 5e-48
Identities = 209/879 (23%), Positives = 322/879 (36%), Gaps = 158/879 (17%)
Query: 64 ESIYTCDHCQQDFESLADLTDHRAHRCPGDGDDDPQLSWVASSPSSKDVASPTQMIGDGC 123
E Y C+ C + F +DL R H+ G + + S Q+I G
Sbjct: 352 EKPYKCEECGKAFNHFSDL---RRHKIIHTGKKPYKCEECGKAFSQSSTLRNHQIIHTGE 408
Query: 124 DLGLGEEEGG---------------TG-LPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFK 167
EE G TG P C+ C K+F S L++H+ IH+ + +K
Sbjct: 409 KPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKHKVIHTREKLYK 468
Query: 168 CTYCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVC 227
C C + F + +H +HTG K Y C EC AF +S HL H H+ KP+KC C
Sbjct: 469 CEECGKAFNNSSILAKHKIIHTGKKPYKCEECGKAFRQSSHLTRHKAIHTGEKPYKCEEC 528
Query: 228 KRGFSSTSSLQSHMQAHKKNKEHLAKSEKEA---------------KKDDFMCDYCEDTF 272
+ FS S+L+ H H K + + +A + + C+ C F
Sbjct: 529 GKAFSHFSALRRHKIIHTGKKPYKCEECGKAFSHFSALRRHKIIHTGEKPYKCEECGKAF 588
Query: 273 SQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQAHANQK-HKCPMCPEQ 331
+ +L H + + + +C C + F + L H H +K +KC C +
Sbjct: 589 KWSSKLTVHKVIH----TAEKPCKCEECGKSFKHFSALRKH-KVIHTREKLYKCEECVKA 643
Query: 332 FSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSA--------TPDSSASVERGST 383
F+S + H H + G SS T + E
Sbjct: 644 FNSFSALMKHKVIH-----TGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGK 698
Query: 384 PDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTC 443
LR K + K Y C C K F+ + L H + IH+ ++ + C
Sbjct: 699 AFKHFSALRKHKVIHTG-----KKPYKCEECGKA-FSQSSSLRKH-EIIHSG--EKPYKC 749
Query: 444 QICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSH 503
+ C + L L H + +H C C + F ++L++H ++ H
Sbjct: 750 EECGKAFKWLSKLTVH-KVIHTAE----------KPCKCEECGKAFKHFSALRKH-KIIH 797
Query: 504 CGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVY 563
G + C +C F S+L +H K+ +P Y
Sbjct: 798 --------TGKKPYKCEECGKAFNDSSTLMKH-----------KIIHTGKKP-------Y 831
Query: 564 SCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSP-KRQRLSA 622
C C G K + H+ HK I H+ + + D SS K+ +L
Sbjct: 832 KCAEC------GKAFKQSSHL-TRHKAI---HTGEKPYKCEECGKDFNNSSTLKKHKLIH 881
Query: 623 SANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLT 682
+ + Y C +C F+NF + H +H + C +C + F L +H
Sbjct: 882 TREKL----YKCEECVKAFNNFSALMKHKIIHTG--EKPYKCEECGKAFKWSSKLTEHKV 935
Query: 683 VHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVK 742
+H T CE CDK F L+KH + Y C C + F++ ++ H +
Sbjct: 936 IH--TGEKPCKCEECDKAFKHFSALRKHKVIHTGKKPYQCDECGKAFNNSSTLTKHKII- 992
Query: 743 HSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHITT 802
H+ EK Y+C C F + + L KH + + K +KC CG+ F+ L H T
Sbjct: 993 HTGEKP-YKCEECGKAFSQSSIL---TKHKIIHSVEKPYKCEECGKAFNQSSHLTRHKTI 1048
Query: 803 HS--KKYNCKFCSKAFHAIILLEK----HLREKHCVFDAATENGTANGVPPMATKKAEPA 856
H+ K Y C+ C KAF L + H REK P KK
Sbjct: 1049 HTGEKPYKCEECGKAFIQCSYLIRHKTIHTREK-----------------PTNVKKVP-- 1089
Query: 857 DLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAY 895
LL NP H + + E Y C+ C A+
Sbjct: 1090 ----KLLSNP-----HTLLDKTIHTGEKPYKCEECAKAF 1119
Score = 180 bits (457), Expect = 7e-45
Identities = 235/1050 (22%), Positives = 379/1050 (36%), Gaps = 186/1050 (17%)
Query: 244 HKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEV 303
HK+ L + ++ F C+ F + K RH ++K +CI C +
Sbjct: 2 HKEGYNKLNQCRTATQRKIFQCNKHMKVFHKYSNRNK---VRH---TKKKTFKCIKCSKS 55
Query: 304 FVDENTLLAHIHQAHANQK-HKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLG 362
F + L+ H + H Q +KC + F S + H H + + +
Sbjct: 56 FFMLSCLIRH-KRIHIRQNIYKCEERGKAFKSFSTLTKHKIIHTEDKPYKYKKCGN---- 110
Query: 363 SVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSL 422
A S+T + G TP + C C K FN
Sbjct: 111 --AFKFSSTFTKHKRIHTGETP------------------------FRCEECGKA-FNQS 143
Query: 423 AVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHC 482
+ L H K IH ++++ C+ C + N N H + +H + C
Sbjct: 144 SNLTDH-KRIHTG--EKTYKCEECGKAFKGSSNFNAH-KVIHTAE----------KPYKC 189
Query: 483 NYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCS 542
C + F ++L++H ++ H G + +C F S+L +H + H
Sbjct: 190 EDCGKTFNHFSALRKH-KIIHTGKKPYKRE--------ECGKAFSQSSTLRKH-EIIHTG 239
Query: 543 VGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAE 602
E P Y C C + + S L + K + K K+ ++
Sbjct: 240 ------EKP-----------YKCEECGKAFKWSSKLTVHKVVHTGEKPYKCEECGKAFSQ 282
Query: 603 QSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQ 662
S + + + K+ Y C +C F++ + H +H +
Sbjct: 283 FSTLKKHKIIHTGKKP-------------YKCEECGKAFNSSSTLMKHKIIHTGE--KPY 327
Query: 663 ACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHC 722
C +C + F L +H +H T Y CE C K F+ DL++H + Y C
Sbjct: 328 KCEECGKAFRQSSHLTRHKAIH--TGEKPYKCEECGKAFNHFSDLRRHKIIHTGKKPYKC 385
Query: 723 TLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHK 782
C + F +++ H + H+ EK Y+C C F+ + L VH K H G K K
Sbjct: 386 EECGKAFSQSSTLRNHQII-HTGEKP-YKCEECGKAFKWSSKLTVH-KVIHTGE--KPCK 440
Query: 783 CIFCGETFSTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENG 840
C CG+ F L+ H I T K Y C+ C KAF+ +L KH
Sbjct: 441 CEECGKAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKH-------------KI 487
Query: 841 TANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVL 900
G P ++ A Q +SH + E Y C+ CG A++
Sbjct: 488 IHTGKKPYKCEECGKAFRQ----------SSHLTRHKAIHTGEKPYKCEECGKAFSHFSA 537
Query: 901 LQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYM 960
L+ H++ +P +KC C + F + LR H H G K Y
Sbjct: 538 LRRHKIIHTGKKP----------------YKCEECGKAFSHFSALRRHKIIHTGE-KPYK 580
Query: 961 CPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGF 1020
C CG+ F LT HKV H+ C C + +H +H R L +
Sbjct: 581 CEECGKAFKWSSKLTVHKVIHTAEKPC-KCEECGKSFKHFSALRKHKVIHT--REKL--Y 635
Query: 1021 RCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFR--SKQD 1078
+C C++ S L H H +K YKC C K F+ SK
Sbjct: 636 KCEECVKAFNSFSALMKHKVIHTG----------------EKPYKCEECGKAFKWSSKLT 679
Query: 1079 LVKLDVNGLPYGLCAGCMARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESH 1138
+ K+ G C C A L + +C EC F + L H
Sbjct: 680 VHKVIHTGEKPCKCEEC--GKAFKHFSALRKHKVIHTGKKPYKCEECGKAFSQSSSLRKH 737
Query: 1139 MQVDHRDLTP----ETSGPRKGTQTSPVPR-----KKTYQCIKCQMTFENEREIQIHVAN 1189
++ H P E K V + +K +C +C F++ ++ H
Sbjct: 738 -EIIHSGEKPYKCEECGKAFKWLSKLTVHKVIHTAEKPCKCEECGKAFKHFSALRKHKII 796
Query: 1190 HMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIF 1249
H ++ ++C+ C + F+ + L+ H I H+ + +KC C F Q++ L +H
Sbjct: 797 HTGKKP--YKCEECGKAFNDSSTLMKHKIIHTGKK---PYKCAECGKAFKQSSHLTRHK- 850
Query: 1250 AVHGQEDKIYDCSQCPQKFFFQTELQNHTM 1279
A+H E K Y C +C + F + L+ H +
Sbjct: 851 AIHTGE-KPYKCEECGKDFNNSSTLKKHKL 879
Score = 145 bits (367), Expect = 2e-34
Identities = 152/663 (22%), Positives = 235/663 (35%), Gaps = 94/663 (14%)
Query: 636 QCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCE 695
QC+ F + K+ + C +C + F L++H +H Y CE
Sbjct: 22 QCNKHMKVFHKYSNRNKVR-HTKKKTFKCIKCSKSFFMLSCLIRHKRIHIRQNI--YKCE 78
Query: 696 SCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTAC 755
K F S L KH + Y C F + H + H+ E +RC C
Sbjct: 79 ERGKAFKSFSTLTKHKIIHTEDKPYKYKKCGNAFKFSSTFTKHKRI-HTGETP-FRCEEC 136
Query: 756 NWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHITTHS--KKYNCKFCS 813
F + ++L H K H G K +KC CG+ F H H+ K Y C+ C
Sbjct: 137 GKAFNQSSNLTDH-KRIHTGE--KTYKCEECGKAFKGSSNFNAHKVIHTAEKPYKCEDCG 193
Query: 814 KAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAPNSHE 873
K F+ L KH G P ++ A Q L+ E
Sbjct: 194 KTFNHFSALRKH-------------KIIHTGKKPYKREECGKAFSQSSTLRKHEI----- 235
Query: 874 ASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCN 933
+ E Y C+ CG A+ L H++ +P +KC
Sbjct: 236 -----IHTGEKPYKCEECGKAFKWSSKLTVHKVVHTGEKP----------------YKCE 274
Query: 934 VCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRIC 993
C + F + L++H H G K Y C CG+ F S TL +HK+ H+ C C
Sbjct: 275 ECGKAFSQFSTLKKHKIIHTGK-KPYKCEECGKAFNSSSTLMKHKIIHTGE-KPYKCEEC 332
Query: 994 KMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAAS 1053
+ H +H + ++C C + +L+ H H K
Sbjct: 333 GKAFRQSSHLTRHKAIHTGEK----PYKCEECGKAFNHFSDLRRHKIIHTGK-------- 380
Query: 1054 SPNGQGLQKLYKCALCLKEFRSKQDLVK---LDVNGLPYGLCAGC-MARSANGQVGGLAP 1109
K YKC C K F L + PY C C A + ++
Sbjct: 381 --------KPYKCEECGKAFSQSSTLRNHQIIHTGEKPY-KCEECGKAFKWSSKLTVHKV 431
Query: 1110 PEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGPRKGTQTSPV------- 1162
++PC +C EC F+ L H + R+ + K S +
Sbjct: 432 IHTGEKPC---KCEECGKAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKII 488
Query: 1163 -PRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHS 1221
KK Y+C +C F + H A H E+ ++C+ C + F + L H I H+
Sbjct: 489 HTGKKPYKCEECGKAFRQSSHLTRHKAIHTGEK--PYKCEECGKAFSHFSALRRHKIIHT 546
Query: 1222 FEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNHTMSQ 1281
+ +KC C F + L++H G +K Y C +C + F + ++L H +
Sbjct: 547 GK---KPYKCEECGKAFSHFSALRRHKIIHTG--EKPYKCEECGKAFKWSSKLTVHKVIH 601
Query: 1282 HAQ 1284
A+
Sbjct: 602 TAE 604
>gi|118600985 zinc finger protein 91 [Homo sapiens]
Length = 1191
Score = 257 bits (657), Expect = 4e-68
Identities = 266/1152 (23%), Positives = 409/1152 (35%), Gaps = 233/1152 (20%)
Query: 69 CDHCQQDFESLADLTDHRA-------HRCPGDGDDDPQLSWVASSPSSKDVASPTQMIGD 121
C C++ F + LT+H+ ++C G QLS + + K + + ++
Sbjct: 212 CKECEKTFHWSSTLTNHKEIHTEDKPYKCEECGKAFKQLSTLTTH---KIICAKEKI--- 265
Query: 122 GCDLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSR 181
Y C+ C K+F+ S L RH++IH+ + P+KC C + F H +
Sbjct: 266 ----------------YKCEECGKAFLWSSTLTRHKRIHTGEKPYKCEECGKAFSHSSTL 309
Query: 182 DRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHM 241
+H ++HTG+K Y C EC AFSRS L H + H+ KP+KC C + FS++S+L +H
Sbjct: 310 AKHKRIHTGEKPYKCEECGKAFSRSSTLAKHKRIHTGEKPYKCKECGKAFSNSSTLANHK 369
Query: 242 QAHKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCP 301
H + K + C C+ F + L KH + + K C C
Sbjct: 370 ITHTEEKP-------------YKCKECDKAFKRLSTLTKHKIIHAGEKLYK----CEECG 412
Query: 302 EVFVDENTLLAHIHQAHANQKHKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVL 361
+ F + L H + +KC C + F+ + H H +
Sbjct: 413 KAFNRSSNLTIHKFIHTGEKPYKCEECGKAFNWSSSLTKHKRFHTREKPFKCKEC----- 467
Query: 362 GSVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNS 421
A + S+T + G P Y C C K F
Sbjct: 468 -GKAFIWSSTLTRHKRIHTGEKP------------------------YKCEECGKA-FRQ 501
Query: 422 LAVLEIHLKTIHA-DKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAF 480
+ L H K IH +KP + C TL N+H K+ + P +
Sbjct: 502 SSTLTKH-KIIHTGEKPYKFEECGKAFRQSLTL---NKH--KIIHSREKP---------Y 546
Query: 481 HCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAH 540
C C + F ++L H ++ H G + C +C F SSL+ H + H
Sbjct: 547 KCKECGKAFKQFSTLTTH-KIIHAG--------KKLYKCEECGKAFNHSSSLSTH-KIIH 596
Query: 541 CSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSK 600
S Y C C + ++ S L+ K I K K+
Sbjct: 597 TGEKS-----------------YKCEECGKAFLWSSTLRRHKRIHTGEKPYKCEECGKAF 639
Query: 601 AEQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLR 660
+ S ++ + + ++ Y C +C FSN + H H E +
Sbjct: 640 SHSSALAKHKRIHTGEKP-------------YKCKECGKAFSNSSTLANHKITHTEE--K 684
Query: 661 KQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLY 720
C +C + F +L +H +H Y CE C K F+ +L H Y
Sbjct: 685 PYKCKECDKTFKRLSTLTKHKIIH--AGEKLYKCEECGKAFNRSSNLTIHKFIHTGEKPY 742
Query: 721 HCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKA 780
C C + F+ S+ H + H+ EK ++C C F + L H K H G K
Sbjct: 743 KCEECGKAFNWSSSLTKHKRI-HTREKP-FKCKECGKAFIWSSTLTRH-KRIHTGE--KP 797
Query: 781 HKCIFCGETFSTEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKH--LREKHCVFDAA 836
+KC CG+ FS L H T H+ K Y CK C KAF L KH + ++
Sbjct: 798 YKCEECGKAFSRSSTLTKHKTIHTGEKPYKCKECGKAFKHSSALAKHKIIHAGEKLYKCE 857
Query: 837 TENGTANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDD------------VDASEP 884
N + T K ++ E P+ E + + E
Sbjct: 858 ECGKAFNQSSNLTTHK---------IIHTKEKPSKSEECDKAFIWSSTLTEHKRIHTREK 908
Query: 885 MYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENG 944
Y C+ CG A++ L H+ +P +KC C + F +
Sbjct: 909 TYKCEECGKAFSQPSHLTTHKRMHTGEKP----------------YKCEECGKAFSQSST 952
Query: 945 LREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFI 1004
L H H G K Y C CG+ F TLTEHK+ H+ C C
Sbjct: 953 LTTHKIIHTGE-KPYKCEECGKAFRKSSTLTEHKIIHTGE-KPYKCEECGKAFSQSSTLT 1010
Query: 1005 EHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLY 1064
H +MH + ++C C + + +L H H +K Y
Sbjct: 1011 RHTRMHTGEK----PYKCEECGKAFNRSSKLTTHKIIHTG----------------EKPY 1050
Query: 1065 KCALCLKEFRSKQDL---VKLDVNGLPYGLCAGC-MARSANGQVGGLAPPEPADRPCAGL 1120
KC C K F S L ++ PY C C A S + + ++P
Sbjct: 1051 KCEECGKAFISSSTLNGHKRIHTREKPY-KCEECGKAFSQSSTLTRHKRLHTGEKP---Y 1106
Query: 1121 RCPECSVKFESAEDLESHMQVDHRDLTPETSGPRKGTQTSPVPRKKTYQCIKCQMTFENE 1180
+C EC F+ + L H ++ H +K Y+C KC F
Sbjct: 1107 KCGECGKAFKESSALTKH-KIIHTG-------------------EKPYKCEKCGKAFNQS 1146
Query: 1181 REIQIHVANHMI 1192
+ H H I
Sbjct: 1147 SILTNHKKIHTI 1158
Score = 239 bits (611), Expect = 9e-63
Identities = 266/1160 (22%), Positives = 424/1160 (36%), Gaps = 209/1160 (18%)
Query: 138 YPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCH 197
+ C+ C KSF + +H+ ++ + KC C + F + H ++HT DK Y C
Sbjct: 182 FKCKKCVKSFCIRLHKTQHKCVYITEKSCKCKECEKTFHWSSTLTNHKEIHTEDKPYKCE 241
Query: 198 ECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEKE 257
EC AF + L H + K +KC C + F +S+L H + H K
Sbjct: 242 ECGKAFKQLSTLTTHKIICAKEKIYKCEECGKAFLWSSTLTRHKRIHTGEKP-------- 293
Query: 258 AKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQA 317
+ C+ C FS + L KH + EK +C C + F +TL H
Sbjct: 294 -----YKCEECGKAFSHSSTLAKH---KRIHTGEKP-YKCEECGKAFSRSSTLAKHKRIH 344
Query: 318 HANQKHKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDSSAS 377
+ +KC C + FS+ + H +H + P
Sbjct: 345 TGEKPYKCKECGKAFSNSSTLANHKITHTEEK----------------------PYKCKE 382
Query: 378 VERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHADKP 437
++ STL + K+ G+ +Y C C K FN + L IH K IH
Sbjct: 383 CDKAFKRLSTLT----KHKIIHAGEK----LYKCEECGKA-FNRSSNLTIH-KFIHTG-- 430
Query: 438 QQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINSLQE 497
++ + C+ C + +L +H ++ H F C C + F ++L
Sbjct: 431 EKPYKCEECGKAFNWSSSLTKH-KRFHTRE----------KPFKCKECGKAFIWSSTLTR 479
Query: 498 HIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPTQ 557
H R+ G + C +C F S+LT+H ++ +
Sbjct: 480 HKRIH---------TGEKPYKCEECGKAFRQSSTLTKH---------------KIIHTGE 515
Query: 558 SFMEVYSCPYCTNSPIFGSILKLTKH--IKENHKNIPLAHSKKSKAEQSPVSSDVEVSSP 615
+ C F L L KH I K K+ + S +++ + +
Sbjct: 516 KPYKFEEC-----GKAFRQSLTLNKHKIIHSREKPYKCKECGKAFKQFSTLTTHKIIHAG 570
Query: 616 KRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQE 675
K+ Y C +C F++ S TH +H + C +C + F
Sbjct: 571 KKL-------------YKCEECGKAFNHSSSLSTHKIIHTGE--KSYKCEECGKAFLWSS 615
Query: 676 SLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSI 735
+L +H +H T Y CE C K FS L KH Y C C + F + ++
Sbjct: 616 TLRRHKRIH--TGEKPYKCEECGKAFSHSSALAKHKRIHTGEKPYKCKECGKAFSNSSTL 673
Query: 736 QVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVE 795
H + H+ EK Y+C C+ F++ + L H K H G K +KC CG+ F+
Sbjct: 674 ANH-KITHTEEKP-YKCKECDKTFKRLSTLTKH-KIIHAGE--KLYKCEECGKAFNRSSN 728
Query: 796 LQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKA 853
L H I T K Y C+ C KAF+ L KH R P K+
Sbjct: 729 LTIHKFIHTGEKPYKCEECGKAFNWSSSLTKHKR-------------IHTREKPFKCKEC 775
Query: 854 EPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRP 913
A + L + + E Y C+ CG A++ L H+ I
Sbjct: 776 GKAFIWSSTLTRHKR----------IHTGEKPYKCEECGKAFSRSSTLTKHK----TIHT 821
Query: 914 GEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLT 973
GE +KC C + F + L +H H G K Y C CG+ F
Sbjct: 822 GEKP------------YKCKECGKAFKHSSALAKHKIIHAGE-KLYKCEECGKAFNQSSN 868
Query: 974 LTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTL 1033
LT HK+ H+K + + C EH ++H + ++C C + +
Sbjct: 869 LTTHKIIHTKEKPSKS-EECDKAFIWSSTLTEHKRIHTREKT----YKCEECGKAFSQPS 923
Query: 1034 ELKIHGTFHMQKL---------AGSSAASSPNGQGL---QKLYKCALCLKEFRSKQDLVK 1081
L H H + A S +++ + + +K YKC C K FR L +
Sbjct: 924 HLTTHKRMHTGEKPYKCEECGKAFSQSSTLTTHKIIHTGEKPYKCEECGKAFRKSSTLTE 983
Query: 1082 ---LDVNGLPYGLCAGC-MARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLES 1137
+ PY C C A S + + ++P +C EC F + L +
Sbjct: 984 HKIIHTGEKPYK-CEECGKAFSQSSTLTRHTRMHTGEKP---YKCEECGKAFNRSSKLTT 1039
Query: 1138 HMQVDHRDLTPETSGPRKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEGIN 1197
H ++ H +K Y+C +C F + + H H E+
Sbjct: 1040 H-KIIHTG-------------------EKPYKCEECGKAFISSSTLNGHKRIHTREKP-- 1077
Query: 1198 HECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDK 1257
++C+ C + F + L H H+ E +KC C F +++ L +H G+ K
Sbjct: 1078 YKCEECGKAFSQSSTLTRHKRLHTGEK---PYKCGECGKAFKESSALTKHKIIHTGE--K 1132
Query: 1258 IYDCSQCPQKFFFQTELQNH 1277
Y C +C + F + L NH
Sbjct: 1133 PYKCEKCGKAFNQSSILTNH 1152
Score = 228 bits (581), Expect = 3e-59
Identities = 254/1138 (22%), Positives = 398/1138 (34%), Gaps = 195/1138 (17%)
Query: 166 FKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCT 225
F+C ++F + +RH HTG K + C +C +F H H + + K KC
Sbjct: 154 FQCGKYLKVFYKFLNSNRHTIRHTGKKCFKCKKCVKSFCIRLHKTQHKCVYITEKSCKCK 213
Query: 226 VCKRGFSSTSSLQSHMQAHKKNK----EHLAKSEKE-----------AKKDDFMCDYCED 270
C++ F +S+L +H + H ++K E K+ K+ AK+ + C+ C
Sbjct: 214 ECEKTFHWSSTLTNHKEIHTEDKPYKCEECGKAFKQLSTLTTHKIICAKEKIYKCEECGK 273
Query: 271 TFSQTEELEKHVLTRHPQL-SEKADLQCIHCPEVFVDENTLLAHIHQAHANQKHKCPMCP 329
F L LTRH ++ + + +C C + F +TL H + +KC C
Sbjct: 274 AF-----LWSSTLTRHKRIHTGEKPYKCEECGKAFSHSSTLAKHKRIHTGEKPYKCEECG 328
Query: 330 EQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDSSASVERGSTPDSTLK 389
+ FS + H H S + + + D K
Sbjct: 329 KAFSRSSTLAKHKRIHTGEKPYKCKECGKAFSNSSTLANHKITHTEEKPYKCKECDKAFK 388
Query: 390 PLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQICLDS 449
L K + G + +Y C C K FN + L IH K IH ++ + C+ C +
Sbjct: 389 RLSTLTKHKIIHAG--EKLYKCEECGKA-FNRSSNLTIH-KFIHTG--EKPYKCEECGKA 442
Query: 450 MPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNAN 509
+L +H ++ H F C C + F ++L H R+
Sbjct: 443 FNWSSSLTKH-KRFHTRE----------KPFKCKECGKAFIWSSTLTRHKRI-------- 483
Query: 510 PSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPTQSFM--------- 560
G + C +C F S+LT+H + H K E QS
Sbjct: 484 -HTGEKPYKCEECGKAFRQSSTLTKH-KIIHTGEKPYKFEECGKAFRQSLTLNKHKIIHS 541
Query: 561 --EVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQ 618
+ Y C C + S L K I K K+ S +S+ + + ++
Sbjct: 542 REKPYKCKECGKAFKQFSTLTTHKIIHAGKKLYKCEECGKAFNHSSSLSTHKIIHTGEKS 601
Query: 619 RLSASANS-------------ISNGE--YPCNQCDLKFSNFESFQTHLKLHLELLLRKQA 663
I GE Y C +C FS+ + H ++H +
Sbjct: 602 YKCEECGKAFLWSSTLRRHKRIHTGEKPYKCEECGKAFSHSSALAKHKRIHTG--EKPYK 659
Query: 664 CPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCT 723
C +C + F + +L H H T Y C+ CDK F + L KH + LY C
Sbjct: 660 CKECGKAFSNSSTLANHKITH--TEEKPYKCKECDKTFKRLSTLTKHKIIHAGEKLYKCE 717
Query: 724 LCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKC 783
C + F+ ++ +H + H+ EK Y+C C F + L KH + K KC
Sbjct: 718 ECGKAFNRSSNLTIHKFI-HTGEKP-YKCEECGKAFNWSSSL---TKHKRIHTREKPFKC 772
Query: 784 IFCGETFSTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENGT 841
CG+ F L H I T K Y C+ C KAF L KH
Sbjct: 773 KECGKAFIWSSTLTRHKRIHTGEKPYKCEECGKAFSRSSTLTKH-------------KTI 819
Query: 842 ANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLL 901
G P K+ G K+ A H+ + A E +Y C+ CG A+ L
Sbjct: 820 HTGEKPYKCKEC------GKAFKHSSALAKHKI----IHAGEKLYKCEECGKAFNQSSNL 869
Query: 902 QNHRLRDHNIRPGEDD------------GSRKKAEFIKGSHKCNVCSRTFFSENGLREHL 949
H++ +P + + K+ + ++KC C + F + L H
Sbjct: 870 TTHKIIHTKEKPSKSEECDKAFIWSSTLTEHKRIHTREKTYKCEECGKAFSQPSHLTTHK 929
Query: 950 QTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQM 1009
+ H G K Y C CG+ F TLT HK+ H+ C C + EH +
Sbjct: 930 RMHTG-EKPYKCEECGKAFSQSSTLTTHKIIHTGE-KPYKCEECGKAFRKSSTLTEHKII 987
Query: 1010 HPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALC 1069
H + ++C C + + + L H H +K YKC C
Sbjct: 988 HTGEK----PYKCEECGKAFSQSSTLTRHTRMHTG----------------EKPYKCEEC 1027
Query: 1070 LKEFRSKQDLVKLDVNGLPYGLCAGCMARSANGQVGGLAPPEPADRPCAGLRCPECSVKF 1129
K F L + ++P +C EC F
Sbjct: 1028 GKAFNRSSKLTTHKI-------------------------IHTGEKP---YKCEECGKAF 1059
Query: 1130 ESAEDLESHMQVDHRDLTPETSGPRKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVAN 1189
S+ L H ++ R+K Y+C +C F + H
Sbjct: 1060 ISSSTLNGHKRIH--------------------TREKPYKCEECGKAFSQSSTLTRHKRL 1099
Query: 1190 HMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQH 1247
H E+ ++C C + F + L H I H+ E +KC C F Q++ L H
Sbjct: 1100 HTGEK--PYKCGECGKAFKESSALTKHKIIHTGE---KPYKCEKCGKAFNQSSILTNH 1152
Score = 211 bits (537), Expect = 4e-54
Identities = 211/889 (23%), Positives = 331/889 (37%), Gaps = 170/889 (19%)
Query: 64 ESIYTCDHCQQDFESLADLTDHR-------AHRCPGDGDDDPQLSWVASSPSSKDVASPT 116
E +Y C+ C + F ++LT H+ ++C G +W +S K +
Sbjct: 403 EKLYKCEECGKAFNRSSNLTIHKFIHTGEKPYKCEECGK---AFNWSSSLTKHKRFHTRE 459
Query: 117 QMIGDGCDLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFK 176
+ P+ C+ C K+FI S L RH++IH+ + P+KC C + F+
Sbjct: 460 K-------------------PFKCKECGKAFIWSSTLTRHKRIHTGEKPYKCEECGKAFR 500
Query: 177 HKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSS 236
+ +H +HTG+K Y EC AF +S L H HS KP+KC C + F S+
Sbjct: 501 QSSTLTKHKIIHTGEKPYKFEECGKAFRQSLTLNKHKIIHSREKPYKCKECGKAFKQFST 560
Query: 237 LQSHMQAHKKNKEHLAKSEKEAK-----------------KDDFMCDYCEDTFSQTEELE 279
L +H H K L K E+ K + + C+ C F + L
Sbjct: 561 LTTHKIIHAGKK--LYKCEECGKAFNHSSSLSTHKIIHTGEKSYKCEECGKAFLWSSTLR 618
Query: 280 KHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQAHANQKHKCPMCPEQFSSVEGVY 339
+H + EK +C C + F + L H + +KC C + FS+ +
Sbjct: 619 RH---KRIHTGEKP-YKCEECGKAFSHSSALAKHKRIHTGEKPYKCKECGKAFSNSSTL- 673
Query: 340 CHLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRD 399
+NH ++ + + D T K L K +
Sbjct: 674 -----------ANHKIT----------------HTEEKPYKCKECDKTFKRLSTLTKHKI 706
Query: 400 DGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEH 459
G + +Y C C K FN + L IH K IH ++ + C+ C + +L +H
Sbjct: 707 IHAG--EKLYKCEECGKA-FNRSSNLTIH-KFIHTG--EKPYKCEECGKAFNWSSSLTKH 760
Query: 460 VRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFC 519
+++H F C C + F ++L H R+ G + C
Sbjct: 761 -KRIHTRE----------KPFKCKECGKAFIWSSTLTRHKRI---------HTGEKPYKC 800
Query: 520 NQCSMGFLTESSLTEH---------IQQAHCSV----GSAKLESPVVQPTQSFMEVYSCP 566
+C F S+LT+H + C SA + ++ + ++Y C
Sbjct: 801 EECGKAFSRSSTLTKHKTIHTGEKPYKCKECGKAFKHSSALAKHKIIHAGE---KLYKCE 857
Query: 567 YCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANS 626
C + F LT H I K SK+E+ + + + +R+ +
Sbjct: 858 ECGKA--FNQSSNLTTH------KIIHTKEKPSKSEECDKAFIWSSTLTEHKRIHTREKT 909
Query: 627 ISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYM 686
Y C +C FS TH ++H + C +C + F +L H +H
Sbjct: 910 -----YKCEECGKAFSQPSHLTTHKRMHTG--EKPYKCEECGKAFSQSSTLTTHKIIH-- 960
Query: 687 TTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNE 746
T Y CE C K F L +H + Y C C + F ++ H + H+ E
Sbjct: 961 TGEKPYKCEECGKAFRKSSTLTEHKIIHTGEKPYKCEECGKAFSQSSTLTRHTRM-HTGE 1019
Query: 747 KKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCH--ITTHS 804
K Y+C C F + + L H K H G K +KC CG+ F + L H I T
Sbjct: 1020 KP-YKCEECGKAFNRSSKLTTH-KIIHTGE--KPYKCEECGKAFISSSTLNGHKRIHTRE 1075
Query: 805 KKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLK 864
K Y C+ C KAF L +H R G P + G K
Sbjct: 1076 KPYKCEECGKAFSQSSTLTRHKR-------------LHTGEKPYKCGEC------GKAFK 1116
Query: 865 NPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRP 913
A H+ + E Y C+ CG A+ +L NH+ + H I P
Sbjct: 1117 ESSALTKHKI----IHTGEKPYKCEKCGKAFNQSSILTNHK-KIHTITP 1160
Score = 181 bits (459), Expect = 4e-45
Identities = 214/896 (23%), Positives = 323/896 (36%), Gaps = 146/896 (16%)
Query: 409 YSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHA 468
Y C C K F L+ L H K I A ++ + C+ C + L H +++H
Sbjct: 238 YKCEECGKA-FKQLSTLTTH-KIICAK--EKIYKCEECGKAFLWSSTLTRH-KRIHTGE- 291
Query: 469 YPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLT 528
+ C C + F+ ++L +H R+ G + C +C F
Sbjct: 292 ---------KPYKCEECGKAFSHSSTLAKHKRIH---------TGEKPYKCEECGKAFSR 333
Query: 529 ESSLTEHIQQAHCS--------VGSAKLESPVV---QPTQSFMEVYSCPYCTNSPIFGSI 577
S+L +H ++ H G A S + + T + + Y C C + F +
Sbjct: 334 SSTLAKH-KRIHTGEKPYKCKECGKAFSNSSTLANHKITHTEEKPYKCKECDKA--FKRL 390
Query: 578 LKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSISNGE--YPCN 635
LTKH I A K K E+ + + R I GE Y C
Sbjct: 391 STLTKH------KIIHAGEKLYKCEECGKAFN-------RSSNLTIHKFIHTGEKPYKCE 437
Query: 636 QCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCE 695
+C F+ S H + H K C +C + F +L +H +H T Y CE
Sbjct: 438 ECGKAFNWSSSLTKHKRFHTREKPFK--CKECGKAFIWSSTLTRHKRIH--TGEKPYKCE 493
Query: 696 SCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTAC 755
C K F L KH + Y C + F +++ H + HS EK Y+C C
Sbjct: 494 ECGKAFRQSSTLTKHKIIHTGEKPYKFEECGKAFRQSLTLNKHKII-HSREKP-YKCKEC 551
Query: 756 NWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCH--ITTHSKKYNCKFCS 813
F++ + L H K H G K +KC CG+ F+ L H I T K Y C+ C
Sbjct: 552 GKAFKQFSTLTTH-KIIHAGK--KLYKCEECGKAFNHSSSLSTHKIIHTGEKSYKCEECG 608
Query: 814 KAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAPNSHE 873
KAF L +H R G P ++ G + A H+
Sbjct: 609 KAFLWSSTLRRHKR-------------IHTGEKPYKCEEC------GKAFSHSSALAKHK 649
Query: 874 ASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCN 933
+ E Y C CG A++ L NH++ +P +KC
Sbjct: 650 R----IHTGEKPYKCKECGKAFSNSSTLANHKITHTEEKP----------------YKCK 689
Query: 934 VCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRIC 993
C +TF + L +H H G K Y C CG+ F LT HK H+ C C
Sbjct: 690 ECDKTFKRLSTLTKHKIIHAGE-KLYKCEECGKAFNRSSNLTIHKFIHTGEKPY-KCEEC 747
Query: 994 KMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAAS 1053
+H ++H + F+C C + + L H H
Sbjct: 748 GKAFNWSSSLTKHKRIHTREKP----FKCKECGKAFIWSSTLTRHKRIHTG--------- 794
Query: 1054 SPNGQGLQKLYKCALCLKEFRSKQDLVK---LDVNGLPYGLCAGCMARSANGQVGGLAPP 1110
+K YKC C K F L K + PY C C A LA
Sbjct: 795 -------EKPYKCEECGKAFSRSSTLTKHKTIHTGEKPYK-CKEC--GKAFKHSSALAKH 844
Query: 1111 EPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGPRKGTQTSPV-------- 1162
+ +C EC F + +L +H + ++ ++ K S
Sbjct: 845 KIIHAGEKLYKCEECGKAFNQSSNLTTHKIIHTKEKPSKSEECDKAFIWSSTLTEHKRIH 904
Query: 1163 PRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSF 1222
R+KTY+C +C F + H H E+ ++C+ C + F + L H I H+
Sbjct: 905 TREKTYKCEECGKAFSQPSHLTTHKRMHTGEK--PYKCEECGKAFSQSSTLTTHKIIHTG 962
Query: 1223 EGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNHT 1278
E +KC C F +++ L +H G +K Y C +C + F + L HT
Sbjct: 963 E---KPYKCEECGKAFRKSSTLTEHKIIHTG--EKPYKCEECGKAFSQSSTLTRHT 1013
Score = 119 bits (299), Expect = 1e-26
Identities = 159/708 (22%), Positives = 240/708 (33%), Gaps = 144/708 (20%)
Query: 580 LTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDL 639
L K+ K H+N+ L KS E +V +L+ + + + C +
Sbjct: 109 LRKYEKCGHENLQLRKGCKSVDE-------CKVHKEGYNKLNQCLTTAQSKVFQCGKYLK 161
Query: 640 KFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDK 699
F F + H H K C +C + F + QH V+ S C+ C+K
Sbjct: 162 VFYKFLNSNRHTIRHTGKKCFK--CKKCVKSFCIRLHKTQHKCVYITEKSCK--CKECEK 217
Query: 700 QFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDF 759
F L H ++HT E K Y+C C F
Sbjct: 218 TFHWSSTLTNHK-EIHT-----------------------------EDKPYKCEECGKAF 247
Query: 760 RKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCH--ITTHSKKYNCKFCSKAFH 817
++ + L H + K +KC CG+ F L H I T K Y C+ C KAF
Sbjct: 248 KQLSTLTTH---KIICAKEKIYKCEECGKAFLWSSTLTRHKRIHTGEKPYKCEECGKAFS 304
Query: 818 AIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASED 877
L KH R G P ++ A + L A
Sbjct: 305 HSSTLAKHKR-------------IHTGEKPYKCEECGKAFSRSSTL----------AKHK 341
Query: 878 DVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSR 937
+ E Y C CG A++ L NH++ +P +KC C +
Sbjct: 342 RIHTGEKPYKCKECGKAFSNSSTLANHKITHTEEKP----------------YKCKECDK 385
Query: 938 TFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPL 997
F + L +H H G K Y C CG+ F LT HK H+ C C
Sbjct: 386 AFKRLSTLTKHKIIHAGE-KLYKCEECGKAFNRSSNLTIHKFIHTGEKPY-KCEECGKAF 443
Query: 998 QSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNG 1057
+H + H + F+C C + + L H H
Sbjct: 444 NWSSSLTKHKRFHTREKP----FKCKECGKAFIWSSTLTRHKRIHTG------------- 486
Query: 1058 QGLQKLYKCALCLKEFRSKQDLVK---LDVNGLPYGL--CAGCMARSANGQVGGLAPPEP 1112
+K YKC C K FR L K + PY C +S +
Sbjct: 487 ---EKPYKCEECGKAFRQSSTLTKHKIIHTGEKPYKFEECGKAFRQSLTLNKHKII--HS 541
Query: 1113 ADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGPRKGTQTSPVPRKKTYQCIK 1172
++P +C EC F+ L +H ++ H KK Y+C +
Sbjct: 542 REKP---YKCKECGKAFKQFSTLTTH-KIIHAG-------------------KKLYKCEE 578
Query: 1173 CQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCP 1232
C F + + H H E+ +++C+ C + F + L H H+ E +KC
Sbjct: 579 CGKAFNHSSSLSTHKIIHTGEK--SYKCEECGKAFLWSSTLRRHKRIHTGEK---PYKCE 633
Query: 1233 VCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNHTMS 1280
C F ++ L +H +H E K Y C +C + F + L NH ++
Sbjct: 634 ECGKAFSHSSALAKHK-RIHTGE-KPYKCKECGKAFSNSSTLANHKIT 679
>gi|6005976 zinc finger protein 208 [Homo sapiens]
Length = 1167
Score = 244 bits (623), Expect = 4e-64
Identities = 264/1128 (23%), Positives = 411/1128 (36%), Gaps = 229/1128 (20%)
Query: 137 PYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 196
PY C+ C K+F + S L +H+ IH+ + +KC C + F +H +HTG+K C
Sbjct: 228 PYRCKECGKAFSKFSILTKHKVIHTGEKSYKCEECGKAFNQSAILTKHKIIHTGEKPNKC 287
Query: 197 HECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEK 256
EC AFS+ L H H+ KP+KC C + FS S+L +H H
Sbjct: 288 EECGKAFSKVSTLTTHKAIHAGEKPYKCKECGKAFSKVSTLITHKAIH------------ 335
Query: 257 EAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQ 316
A + + C C FS+ L KH + + + +C C + + +TL H +
Sbjct: 336 -AGEKPYKCKECGKAFSKFSILTKHKVIH----TGEKPYKCEECGKAYKWPSTLSYH-KK 389
Query: 317 AHANQK-HKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDSS 375
H +K +KC C + FS ++ L H + + G + SS +
Sbjct: 390 IHTGEKPYKCEECGKGFS----MFSILTKHEVIHTGEKPYKCEE-CGKAFNWSSNLMEHK 444
Query: 376 ASVERGSTPDSTLKPLRGQKKMRDDGQG--WTKVV------------YSCPYCSKRDFNS 421
+ G TP K + G+G W+ + Y C C K FN
Sbjct: 445 -KIHTGETP----------YKCEECGKGFSWSSTLSYHKKIHTVEKPYKCEECGKA-FNQ 492
Query: 422 LAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFH 481
A+L H + +KP + C+ C + + L H + +H +
Sbjct: 493 SAILIKHKRIHTGEKP---YKCEECGKTFSKVSTLTTH-KAIHAGE----------KPYK 538
Query: 482 CNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHC 541
C C + F +++L H + H G + C +C F S LT+H + H
Sbjct: 539 CKECGKTFIKVSTLTTH-KAIHA--------GEKPYKCKECGKAFSKFSILTKH-KVIHT 588
Query: 542 SVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKA 601
E P Y C C + + S L K I K KS +
Sbjct: 589 G------EKP-----------YKCEECGKAFNWSSNLMEHKRIHTGEKPYKCEECGKSFS 631
Query: 602 EQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRK 661
S ++ + + ++ Y C +C + + H K+H + +
Sbjct: 632 TFSVLTKHKVIHTGEK-------------PYKCEECGKAYKWSSTLSYHKKIH--TVEKP 676
Query: 662 QACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYH 721
C +C + F+ L++H +H T Y CE C K FS V L H Y
Sbjct: 677 YKCEECGKAFNRSAILIKHKRIH--TDEKPYKCEECGKTFSKVSTLTTHKAIHAGEKPYK 734
Query: 722 CTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAH 781
C C + F SK SI V H+ EK Y+C C ++ + L H K H G K +
Sbjct: 735 CKECGKAF-SKFSILTKHKVIHTGEKP-YKCEECGKAYKWPSTLSYH-KKIHTGE--KPY 789
Query: 782 KCIFCGETFSTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFDAATEN 839
KC CG+ FS L H I T K Y C+ C KAF + + KH ++ H
Sbjct: 790 KCEECGKGFSMFSILTKHEVIHTGEKPYKCEECGKAFSWLSVFSKH-KKTH--------- 839
Query: 840 GTANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEV 899
A +K + G H+ + E Y C+ CG A+
Sbjct: 840 ---------AGEKFYKCEACGKAYNTFSILTKHKV----IHTGEKPYKCEECGKAFNWSS 886
Query: 900 LLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHY 959
L H+ I GE +KC C + F + L EH TH G K Y
Sbjct: 887 NLMEHK----KIHTGET------------PYKCEECDKAFSWPSSLTEHKATHAG-EKPY 929
Query: 960 MCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTG 1019
C CG+ F LTEHK TH+ + C C +EH ++H +
Sbjct: 930 KCEECGKAFSWPSRLTEHKATHAGE-EPYKCEECGKAFNWSSNLMEHKRIHTGEK----P 984
Query: 1020 FRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDL 1079
++C C ++ ++ L H H +K YKC C K ++ L
Sbjct: 985 YKCEECGKSFSTFSILTKHKVIHTG----------------EKPYKCEECGKAYKWSSTL 1028
Query: 1080 VKLDVNGLPYGLCAGCMARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHM 1139
S + ++ + P +C EC F L H
Sbjct: 1029 -------------------SYHKKIHTVEKP---------YKCEECGKGFVMFSILAKH- 1059
Query: 1140 QVDHRDLTPETSGPRKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHE 1199
+V H +K Y+C +C ++ ++ H H E+ ++
Sbjct: 1060 KVIHTG-------------------EKLYKCEECGKAYKWPSTLRYHKKIHTGEK--PYK 1098
Query: 1200 CKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQH 1247
C+ C + F + + L H + H+ E +KC C F + +H
Sbjct: 1099 CEECGKAFSTFSILTKHKVIHTGE---KPYKCEECGKAFSWLSVFSKH 1143
Score = 239 bits (610), Expect = 1e-62
Identities = 265/1143 (23%), Positives = 418/1143 (36%), Gaps = 235/1143 (20%)
Query: 140 CQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCHEC 199
C+ +SF LS+L +H++I++ + +KC + F + + HTG+K Y C EC
Sbjct: 175 CKEYVRSFCMLSHLSQHKRIYTRENSYKCEEGGKAFNWSSTLTYYKSAHTGEKPYRCKEC 234
Query: 200 EAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEKEAK 259
AFS+ L H H+ K +KC C + F+ ++ L H H K +
Sbjct: 235 GKAFSKFSILTKHKVIHTGEKSYKCEECGKAFNQSAILTKHKIIHTGEKPN--------- 285
Query: 260 KDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQAHA 319
C+ C FS+ L H + K C C + F +TL+ H HA
Sbjct: 286 ----KCEECGKAFSKVSTLTTHKAIHAGEKPYK----CKECGKAFSKVSTLITH-KAIHA 336
Query: 320 NQK-HKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDSSASV 378
+K +KC C + FS + H H + +
Sbjct: 337 GEKPYKCKECGKAFSKFSILTKHKVIH------------------TGEKPYKCEECGKAY 378
Query: 379 ERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHADKPQ 438
+ ST K G+K Y C C K F+ ++L H +KP
Sbjct: 379 KWPSTLSYHKKIHTGEKP------------YKCEECGK-GFSMFSILTKHEVIHTGEKP- 424
Query: 439 QSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINSLQEH 498
+ C+ C + NL EH +K+H + + C C + F+ ++L H
Sbjct: 425 --YKCEECGKAFNWSSNLMEH-KKIHTGE----------TPYKCEECGKGFSWSSTLSYH 471
Query: 499 IRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPTQS 558
++ + C +C F + L +H ++ H E P
Sbjct: 472 KKIHTV---------EKPYKCEECGKAFNQSAILIKH-KRIHTG------EKP------- 508
Query: 559 FMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQ 618
Y C C + F + LT H K H A K K ++ + ++VS+
Sbjct: 509 ----YKCEECGKT--FSKVSTLTTH-KAIH-----AGEKPYKCKECG-KTFIKVSTLTTH 555
Query: 619 RLSASANSISNGE--YPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQES 676
+ +I GE Y C +C FS F H +H + C +C + F+ +
Sbjct: 556 K------AIHAGEKPYKCKECGKAFSKFSILTKHKVIHTGE--KPYKCEECGKAFNWSSN 607
Query: 677 LLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQ 736
L++H +H T Y CE C K FS+ L KH + Y C C + + ++
Sbjct: 608 LMEHKRIH--TGEKPYKCEECGKSFSTFSVLTKHKVIHTGEKPYKCEECGKAYKWSSTLS 665
Query: 737 VHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVEL 796
H + H+ EK Y+C C F + A L +KH + K +KC CG+TFS L
Sbjct: 666 YHKKI-HTVEKP-YKCEECGKAFNRSAIL---IKHKRIHTDEKPYKCEECGKTFSKVSTL 720
Query: 797 QCHITTHS--KKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAE 854
H H+ K Y CK C KAF +L KH G P ++
Sbjct: 721 TTHKAIHAGEKPYKCKECGKAFSKFSILTKH-------------KVIHTGEKPYKCEEC- 766
Query: 855 PADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPG 914
G K P + H+ + E Y C+ CG ++M +L H + I G
Sbjct: 767 -----GKAYKWPSTLSYHKK----IHTGEKPYKCEECGKGFSMFSILTKHEV----IHTG 813
Query: 915 EDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTL 974
E +KC C + F + +H +TH G K Y C CG+ + + L
Sbjct: 814 EKP------------YKCEECGKAFSWLSVFSKHKKTHAGE-KFYKCEACGKAYNTFSIL 860
Query: 975 TEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLE 1034
T+HKV H+ C C +EH ++H T ++C C + +
Sbjct: 861 TKHKVIHTGEKPY-KCEECGKAFNWSSNLMEHKKIH----TGETPYKCEECDKAFSWPSS 915
Query: 1035 LKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLVKLDVNGLPYGLCAG 1094
L H H AG +K YKC C K F L +
Sbjct: 916 LTEHKATH----AG------------EKPYKCEECGKAFSWPSRLTEHKATH-------- 951
Query: 1095 CMARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGPR 1154
A EP +C EC F + +L H ++ +
Sbjct: 952 -------------AGEEP-------YKCEECGKAFNWSSNLMEHKRIHTGE--------- 982
Query: 1155 KGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLL 1214
K Y+C +C +F + H H E+ ++C+ C + + + L
Sbjct: 983 -----------KPYKCEECGKSFSTFSILTKHKVIHTGEKP--YKCEECGKAYKWSSTLS 1029
Query: 1215 CHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTEL 1274
H H+ E +KC C FV + L +H G+ K+Y C +C + + + + L
Sbjct: 1030 YHKKIHTVEK---PYKCEECGKGFVMFSILAKHKVIHTGE--KLYKCEECGKAYKWPSTL 1084
Query: 1275 QNH 1277
+ H
Sbjct: 1085 RYH 1087
Score = 235 bits (600), Expect = 2e-61
Identities = 270/1155 (23%), Positives = 416/1155 (36%), Gaps = 217/1155 (18%)
Query: 147 FIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRS 206
F + S RH+ H+ K +C R F +H +++T + Y C E AF+ S
Sbjct: 154 FHKCSNSNRHKIRHTGKKHLQCKEYVRSFCMLSHLSQHKRIYTRENSYKCEEGGKAFNWS 213
Query: 207 DHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEKEAKKDDFMCD 266
L + H+ KP++C C + FS S L H H K + C+
Sbjct: 214 STLTYYKSAHTGEKPYRCKECGKAFSKFSILTKHKVIHTGEK-------------SYKCE 260
Query: 267 YCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQAHANQK-HKC 325
C F+Q+ L KH + + K C C + F +TL H HA +K +KC
Sbjct: 261 ECGKAFNQSAILTKHKIIHTGEKPNK----CEECGKAFSKVSTLTTH-KAIHAGEKPYKC 315
Query: 326 PMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDSSASVERGSTPD 385
C + FS V + H H + G S S + G P
Sbjct: 316 KECGKAFSKVSTLITHKAIH-----AGEKPYKCKECGKAFSKFSILTKHKV-IHTGEKP- 368
Query: 386 STLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQI 445
Y C C K + + L H K +KP + C+
Sbjct: 369 -----------------------YKCEECGKA-YKWPSTLSYHKKIHTGEKP---YKCEE 401
Query: 446 CLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCG 505
C L +H V+ G + C C + F ++L EH ++
Sbjct: 402 CGKGFSMFSILTKH----------EVIHTGE-KPYKCEECGKAFNWSSNLMEHKKI---- 446
Query: 506 PNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEV--- 562
G + C +C GF S+L+ H ++ H K E QS + +
Sbjct: 447 -----HTGETPYKCEECGKGFSWSSTLSYH-KKIHTVEKPYKCEECGKAFNQSAILIKHK 500
Query: 563 --------YSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSS 614
Y C C + F + LT H K H A K K ++ + ++VS+
Sbjct: 501 RIHTGEKPYKCEECGKT--FSKVSTLTTH-KAIH-----AGEKPYKCKECG-KTFIKVST 551
Query: 615 PKRQRLSASANSISNGE--YPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFD 672
+ +I GE Y C +C FS F H +H + C +C + F+
Sbjct: 552 ------LTTHKAIHAGEKPYKCKECGKAFSKFSILTKHKVIHTG--EKPYKCEECGKAFN 603
Query: 673 SQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSK 732
+L++H +H T Y CE C K FS+ L KH + Y C C + +
Sbjct: 604 WSSNLMEHKRIH--TGEKPYKCEECGKSFSTFSVLTKHKVIHTGEKPYKCEECGKAYKWS 661
Query: 733 VSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFST 792
++ H + H+ EK Y+C C F + A L +KH + K +KC CG+TFS
Sbjct: 662 STLSYHKKI-HTVEKP-YKCEECGKAFNRSAIL---IKHKRIHTDEKPYKCEECGKTFSK 716
Query: 793 EVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMAT 850
L H H+ K Y CK C KAF +L KH G P
Sbjct: 717 VSTLTTHKAIHAGEKPYKCKECGKAFSKFSILTKH-------------KVIHTGEKPYKC 763
Query: 851 KKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHN 910
++ G K P + H+ + E Y C+ CG ++M +L H +
Sbjct: 764 EEC------GKAYKWPSTLSYHK----KIHTGEKPYKCEECGKGFSMFSILTKHEV---- 809
Query: 911 IRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPS 970
I GE +KC C + F + +H +TH G K Y C CG+ + +
Sbjct: 810 IHTGEK------------PYKCEECGKAFSWLSVFSKHKKTHAG-EKFYKCEACGKAYNT 856
Query: 971 LLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVT 1030
LT+HKV H+ C C +EH ++H T ++C C + +
Sbjct: 857 FSILTKHKVIHTGE-KPYKCEECGKAFNWSSNLMEHKKIH----TGETPYKCEECDKAFS 911
Query: 1031 STLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLVKLDVNGLPYG 1090
L H H AG +K YKC C K F L +
Sbjct: 912 WPSSLTEHKATH----AG------------EKPYKCEECGKAFSWPSRLTEHKATH---- 951
Query: 1091 LCAGCMARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPET 1150
A EP +C EC F + +L H ++ + +
Sbjct: 952 -----------------AGEEP-------YKCEECGKAFNWSSNLMEHKRIHTGEKPYKC 987
Query: 1151 SGPRKGTQTSPVPRK--------KTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKL 1202
K T + K K Y+C +C ++ + H H +E+ ++C+
Sbjct: 988 EECGKSFSTFSILTKHKVIHTGEKPYKCEECGKAYKWSSTLSYHKKIHTVEK--PYKCEE 1045
Query: 1203 CNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCS 1262
C + F + L H + H+ E + +KC C + + L+ H +H E K Y C
Sbjct: 1046 CGKGFVMFSILAKHKVIHTGEKL---YKCEECGKAYKWPSTLRYH-KKIHTGE-KPYKCE 1100
Query: 1263 QCPQKFFFQTELQNH 1277
+C + F + L H
Sbjct: 1101 ECGKAFSTFSILTKH 1115
Score = 229 bits (584), Expect = 1e-59
Identities = 234/973 (24%), Positives = 357/973 (36%), Gaps = 173/973 (17%)
Query: 64 ESIYTCDHCQQDFESLADLTDHRA-------HRCPGDGDDDPQLSWVASSPSSKDVASPT 116
E Y C C + F + LT H+ ++C G W ++ K + +
Sbjct: 338 EKPYKCKECGKAFSKFSILTKHKVIHTGEKPYKCEECGK---AYKWPSTLSYHKKIHT-- 392
Query: 117 QMIGDGCDLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFK 176
GE+ PY C+ C K F S L +HE IH+ + P+KC C + F
Sbjct: 393 -----------GEK------PYKCEECGKGFSMFSILTKHEVIHTGEKPYKCEECGKAFN 435
Query: 177 HKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSS 236
+ H K+HTG+ Y C EC FS S L H K H+ KP+KC C + F+ ++
Sbjct: 436 WSSNLMEHKKIHTGETPYKCEECGKGFSWSSTLSYHKKIHTVEKPYKCEECGKAFNQSAI 495
Query: 237 LQSHMQAHKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQ 296
L H + H K + C+ C TFS+ L H + + +
Sbjct: 496 LIKHKRIHTGEK-------------PYKCEECGKTFSKVSTLTTHKAIH----AGEKPYK 538
Query: 297 CIHCPEVFVDENTLLAHIHQAHANQK-HKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSV 355
C C + F+ +TL H HA +K +KC C + FS + L H+ +
Sbjct: 539 CKECGKTFIKVSTLTTH-KAIHAGEKPYKCKECGKAFSK----FSILTKHKVIHTGEKPY 593
Query: 356 SPDPVLGSVASMSS--------ATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKV 407
+ G + SS T + E ST L K + +
Sbjct: 594 KCEE-CGKAFNWSSNLMEHKRIHTGEKPYKCEECGKSFSTFSVLTKHKVIHTG-----EK 647
Query: 408 VYSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNH 467
Y C C K + + L H K +KP + C+ C + L +H +++H +
Sbjct: 648 PYKCEECGKA-YKWSSTLSYHKKIHTVEKP---YKCEECGKAFNRSAILIKH-KRIHTDE 702
Query: 468 AYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFL 527
+ C C + F+ +++L H + H G + C +C F
Sbjct: 703 ----------KPYKCEECGKTFSKVSTLTTH-KAIHA--------GEKPYKCKECGKAFS 743
Query: 528 TESSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKEN 587
S LT+H + H E P Y C C + + S L K I
Sbjct: 744 KFSILTKH-KVIHTG------EKP-----------YKCEECGKAYKWPSTLSYHKKIHTG 785
Query: 588 HKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESF 647
K K + S ++ + + ++ Y C +C FS F
Sbjct: 786 EKPYKCEECGKGFSMFSILTKHEVIHTGEK-------------PYKCEECGKAFSWLSVF 832
Query: 648 QTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDL 707
H K H K C C + +++ L +H +H T Y CE C K F+ +L
Sbjct: 833 SKHKKTHAGEKFYK--CEACGKAYNTFSILTKHKVIH--TGEKPYKCEECGKAFNWSSNL 888
Query: 708 QKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQV 767
+H Y C C + F S+ H A H+ EK Y+C C F + L
Sbjct: 889 MEHKKIHTGETPYKCEECDKAFSWPSSLTEHKAT-HAGEKP-YKCEECGKAFSWPSRLTE 946
Query: 768 HVKHSHLGNPAKAHKCIFCGETFSTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKH 825
H K +H G + +KC CG+ F+ L H I T K Y C+ C K+F +L KH
Sbjct: 947 H-KATHAGE--EPYKCEECGKAFNWSSNLMEHKRIHTGEKPYKCEECGKSFSTFSILTKH 1003
Query: 826 LREKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPM 885
G P ++ G K + H+ + E
Sbjct: 1004 -------------KVIHTGEKPYKCEEC------GKAYKWSSTLSYHK----KIHTVEKP 1040
Query: 886 YGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGL 945
Y C+ CG + M +L H++ I GE +KC C + + + L
Sbjct: 1041 YKCEECGKGFVMFSILAKHKV----IHTGEK------------LYKCEECGKAYKWPSTL 1084
Query: 946 REHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIE 1005
R H + H G K Y C CG+ F + LT+HKV H+ C C F +
Sbjct: 1085 RYHKKIHTG-EKPYKCEECGKAFSTFSILTKHKVIHTGE-KPYKCEECGKAFSWLSVFSK 1142
Query: 1006 HCQMHPDLRNSLT 1018
H ++H + N T
Sbjct: 1143 HKKIHTGVPNPPT 1155
Score = 223 bits (569), Expect = 7e-58
Identities = 242/1014 (23%), Positives = 365/1014 (35%), Gaps = 191/1014 (18%)
Query: 64 ESIYTCDHCQQDFESLADLTDHRAHRCPGDGDDDPQLSWVASSPSSKDVASPTQMIGDGC 123
E Y C+ C + F A LT H+ + P SK T
Sbjct: 254 EKSYKCEECGKAFNQSAILTKHKIIHT----GEKPNKCEECGKAFSKVSTLTTHKA---- 305
Query: 124 DLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDR 183
+ GE+ PY C+ C K+F ++S L H+ IH+ + P+KC C + F +
Sbjct: 306 -IHAGEK------PYKCKECGKAFSKVSTLITHKAIHAGEKPYKCKECGKAFSKFSILTK 358
Query: 184 HIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQA 243
H +HTG+K Y C EC A+ L H K H+ KP+KC C +GFS S L H
Sbjct: 359 HKVIHTGEKPYKCEECGKAYKWPSTLSYHKKIHTGEKPYKCEECGKGFSMFSILTKHEVI 418
Query: 244 HKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEV 303
H K + C+ C F+ + L +H + + +C C +
Sbjct: 419 HTGEK-------------PYKCEECGKAFNWSSNLMEHKKIH----TGETPYKCEECGKG 461
Query: 304 FVDENTLLAHIHQAHANQKHKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGS 363
F +TL H + +KC C + F+ L H++ + + +
Sbjct: 462 FSWSSTLSYHKKIHTVEKPYKCEECGKAFNQ----SAILIKHKRIHTGEKPYKCEECGKT 517
Query: 364 VASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLA 423
+ +S+ T + ++ G P Y C C K F ++
Sbjct: 518 FSKVSTLT--THKAIHAGEKP------------------------YKCKECGK-TFIKVS 550
Query: 424 VLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCN 483
L H K IHA ++ + C+ C + L +H + +H + C
Sbjct: 551 TLTTH-KAIHAG--EKPYKCKECGKAFSKFSILTKH-KVIHTGE----------KPYKCE 596
Query: 484 YCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSV 543
C + F ++L EH R+ G + C +C F T S LT+H + H
Sbjct: 597 ECGKAFNWSSNLMEHKRI---------HTGEKPYKCEECGKSFSTFSVLTKH-KVIHTG- 645
Query: 544 GSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQ 603
E P Y C C + + S L HK I K K E+
Sbjct: 646 -----EKP-----------YKCEECGKAYKWSSTLSY-------HKKIHTV-EKPYKCEE 681
Query: 604 SPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQA 663
+ + K +R+ Y C +C FS + TH +H +
Sbjct: 682 CGKAFNRSAILIKHKRIHTDEK-----PYKCEECGKTFSKVSTLTTHKAIHAG--EKPYK 734
Query: 664 CPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVL-YHC 722
C +C + F L +H +H T Y CE C K + L H +HT Y C
Sbjct: 735 CKECGKAFSKFSILTKHKVIH--TGEKPYKCEECGKAYKWPSTLSYH-KKIHTGEKPYKC 791
Query: 723 TLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHK 782
C + F S SI V H+ EK Y+C C F + L V KH K +K
Sbjct: 792 EECGKGF-SMFSILTKHEVIHTGEKP-YKCEECGKAF---SWLSVFSKHKKTHAGEKFYK 846
Query: 783 CIFCGETFSTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENG 840
C CG+ ++T L H I T K Y C+ C KAF+ L +H +
Sbjct: 847 CEACGKAYNTFSILTKHKVIHTGEKPYKCEECGKAFNWSSNLMEHKK------------- 893
Query: 841 TANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVL 900
G P ++ + A P + H+A+ A E Y C+ CG A++
Sbjct: 894 IHTGETPYKCEECDKA------FSWPSSLTEHKATH----AGEKPYKCEECGKAFSWPSR 943
Query: 901 LQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYM 960
L H+ P +KC C + F + L EH + H G K Y
Sbjct: 944 LTEHKATHAGEEP----------------YKCEECGKAFNWSSNLMEHKRIHTG-EKPYK 986
Query: 961 CPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGF 1020
C CG+ F + LT+HKV H+ C C + H ++H + +
Sbjct: 987 CEECGKSFSTFSILTKHKVIHTGE-KPYKCEECGKAYKWSSTLSYHKKIHTVEK----PY 1041
Query: 1021 RCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFR 1074
+C C + L H H +KLYKC C K ++
Sbjct: 1042 KCEECGKGFVMFSILAKHKVIHTG----------------EKLYKCEECGKAYK 1079
Score = 157 bits (398), Expect = 5e-38
Identities = 210/957 (21%), Positives = 331/957 (34%), Gaps = 190/957 (19%)
Query: 402 QGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHT------CQICLDSMPTLYN 455
+G+ K+ S + F + K ++++ + HT C+ + S L +
Sbjct: 128 EGYNKLNQSLTTTQSKVFQRGKYANVFHKCSNSNRHKIRHTGKKHLQCKEYVRSFCMLSH 187
Query: 456 LNEHVRKLHKNHAYPVMQFGNI-----------------SAFHCNYCPEMFADINSLQEH 498
L++H R + ++Y + G + C C + F+ + L +H
Sbjct: 188 LSQHKRIYTRENSYKCEEGGKAFNWSSTLTYYKSAHTGEKPYRCKECGKAFSKFSILTKH 247
Query: 499 IRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPTQS 558
+V H G ++ C +C F + LT+H K+ +P +
Sbjct: 248 -KVIHTG--------EKSYKCEECGKAFNQSAILTKH-----------KIIHTGEKPNK- 286
Query: 559 FMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQ 618
C C + F + LT H K H K+ S VS+ +
Sbjct: 287 ------CEECGKA--FSKVSTLTTH-KAIHAGEKPYKCKECGKAFSKVSTLI-------- 329
Query: 619 RLSASANSISNGE--YPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQES 676
+ +I GE Y C +C FS F H +H + C +C + + +
Sbjct: 330 ----THKAIHAGEKPYKCKECGKAFSKFSILTKHKVIHTGE--KPYKCEECGKAYKWPST 383
Query: 677 LLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQ 736
L H +H T Y CE C K FS L KH + Y C C + F+ ++
Sbjct: 384 LSYHKKIH--TGEKPYKCEECGKGFSMFSILTKHEVIHTGEKPYKCEECGKAFNWSSNLM 441
Query: 737 VHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVEL 796
H + H+ E Y+C C F + L H K + K +KC CG+ F+ L
Sbjct: 442 EHKKI-HTGETP-YKCEECGKGFSWSSTLSYHKK---IHTVEKPYKCEECGKAFNQSAIL 496
Query: 797 QCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAE 854
H I T K Y C+ C K F + L H G P K+
Sbjct: 497 IKHKRIHTGEKPYKCEECGKTFSKVSTLTTH-------------KAIHAGEKPYKCKECG 543
Query: 855 PADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPG 914
++ L +H+A + A E Y C CG A++ +L H++ I G
Sbjct: 544 KTFIKVSTL------TTHKA----IHAGEKPYKCKECGKAFSKFSILTKHKV----IHTG 589
Query: 915 EDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTL 974
E +KC C + F + L EH + H G K Y C CG+ F + L
Sbjct: 590 EKP------------YKCEECGKAFNWSSNLMEHKRIHTGE-KPYKCEECGKSFSTFSVL 636
Query: 975 TEHKVTHS-----------------------KSLDT----GTCRICKMPLQSEEEFIEHC 1007
T+HKV H+ K + T C C I+H
Sbjct: 637 TKHKVIHTGEKPYKCEECGKAYKWSSTLSYHKKIHTVEKPYKCEECGKAFNRSAILIKHK 696
Query: 1008 QMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPN-GQGLQKL--- 1063
++H D + ++C C +T + L H H AG G+ K
Sbjct: 697 RIHTDEK----PYKCEECGKTFSKVSTLTTHKAIH----AGEKPYKCKECGKAFSKFSIL 748
Query: 1064 ------------YKCALCLKEFRSKQDL---VKLDVNGLPYGLCAGCMARSANGQVGGLA 1108
YKC C K ++ L K+ PY C C + + L
Sbjct: 749 TKHKVIHTGEKPYKCEECGKAYKWPSTLSYHKKIHTGEKPY-KCEECGKGFSMFSI--LT 805
Query: 1109 PPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGPRKGTQTSPVPRK--- 1165
E +C EC F H + + + K T + K
Sbjct: 806 KHEVIHTGEKPYKCEECGKAFSWLSVFSKHKKTHAGEKFYKCEACGKAYNTFSILTKHKV 865
Query: 1166 -----KTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEH 1220
K Y+C +C F + H H E ++C+ C++ F P+ L H H
Sbjct: 866 IHTGEKPYKCEECGKAFNWSSNLMEHKKIHTGE--TPYKCEECDKAFSWPSSLTEHKATH 923
Query: 1221 SFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNH 1277
+ E +KC C F ++L +H G+E Y C +C + F + + L H
Sbjct: 924 AGE---KPYKCEECGKAFSWPSRLTEHKATHAGEEP--YKCEECGKAFNWSSNLMEH 975
Score = 125 bits (314), Expect = 3e-28
Identities = 126/593 (21%), Positives = 206/593 (34%), Gaps = 147/593 (24%)
Query: 63 DESIYTCDHCQQDFESLADLTDHRAHRCPGDGDDDPQLSWVASSPSSKDVASPTQMIGDG 122
DE Y C+ C + F ++ LT H+A
Sbjct: 701 DEKPYKCEECGKTFSKVSTLTTHKA----------------------------------- 725
Query: 123 CDLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRD 182
+ GE+ PY C+ C K+F + S L +H+ IH+ + P+KC C + +K +
Sbjct: 726 --IHAGEK------PYKCKECGKAFSKFSILTKHKVIHTGEKPYKCEECGKAYKWPSTLS 777
Query: 183 RHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQ 242
H K+HTG+K Y C EC FS L H H+ KP+KC C + FS S H +
Sbjct: 778 YHKKIHTGEKPYKCEECGKGFSMFSILTKHEVIHTGEKPYKCEECGKAFSWLSVFSKHKK 837
Query: 243 AHKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQL-SEKADLQCIHCP 301
H K + ++ C +TFS +LT+H + + + +C C
Sbjct: 838 THAGEKFYKCEA----------CGKAYNTFS--------ILTKHKVIHTGEKPYKCEECG 879
Query: 302 EVFVDENTLLAHIHQAHANQKHKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVL 361
+ F + L+ H +KC C + FS + H +H +
Sbjct: 880 KAFNWSSNLMEHKKIHTGETPYKCEECDKAFSWPSSLTEHKATH-----AGEKPYKCEEC 934
Query: 362 GSVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNS 421
G S S + A+ G P Y C C K FN
Sbjct: 935 GKAFSWPSRLTEHKAT-HAGEEP------------------------YKCEECGKA-FNW 968
Query: 422 LAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFH 481
+ L H + +KP + C+ C S T L +H + +H +
Sbjct: 969 SSNLMEHKRIHTGEKP---YKCEECGKSFSTFSILTKH-KVIHTGE----------KPYK 1014
Query: 482 CNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHC 541
C C + + ++L H ++ + C +C GF+ S L +H
Sbjct: 1015 CEECGKAYKWSSTLSYHKKIHTV---------EKPYKCEECGKGFVMFSILAKH------ 1059
Query: 542 SVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKA 601
+ + ++Y C C + + S L+ K I K K+ +
Sbjct: 1060 ------------KVIHTGEKLYKCEECGKAYKWPSTLRYHKKIHTGEKPYKCEECGKAFS 1107
Query: 602 EQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLH 654
S ++ + + ++ Y C +C FS F H K+H
Sbjct: 1108 TFSILTKHKVIHTGEK-------------PYKCEECGKAFSWLSVFSKHKKIH 1147
Score = 96.7 bits (239), Expect = 1e-19
Identities = 71/270 (26%), Positives = 116/270 (42%), Gaps = 37/270 (13%)
Query: 1 MHKKRVEEGEAS------DFSLAWDSSVT---AAGGLEGEPECDQKTSRALEDRNSVTSQ 51
M K++ GE D + +W SS+T A E +C++ +A + +T
Sbjct: 889 MEHKKIHTGETPYKCEECDKAFSWPSSLTEHKATHAGEKPYKCEE-CGKAFSWPSRLTEH 947
Query: 52 EERNEDDEDMEDESIYTCDHCQQDFESLADLTDH-RAHRCPGDGDDDPQLSWVASSPSSK 110
+ + +E Y C+ C + F ++L +H R H G+ + S S+
Sbjct: 948 KATHAGEEP------YKCEECGKAFNWSSNLMEHKRIHT----GEKPYKCEECGKSFSTF 997
Query: 111 DVASPTQMIGDG-----CD-----------LGLGEEEGGTGLPYPCQFCDKSFIRLSYLK 154
+ + ++I G C+ L ++ PY C+ C K F+ S L
Sbjct: 998 SILTKHKVIHTGEKPYKCEECGKAYKWSSTLSYHKKIHTVEKPYKCEECGKGFVMFSILA 1057
Query: 155 RHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLK 214
+H+ IH+ + +KC C + +K + H K+HTG+K Y C EC AFS L H
Sbjct: 1058 KHKVIHTGEKLYKCEECGKAYKWPSTLRYHKKIHTGEKPYKCEECGKAFSTFSILTKHKV 1117
Query: 215 THSSSKPFKCTVCKRGFSSTSSLQSHMQAH 244
H+ KP+KC C + FS S H + H
Sbjct: 1118 IHTGEKPYKCEECGKAFSWLSVFSKHKKIH 1147
Score = 67.0 bits (162), Expect = 1e-10
Identities = 52/188 (27%), Positives = 79/188 (42%), Gaps = 30/188 (15%)
Query: 64 ESIYTCDHCQQDFESLADLTDHRA-------HRCPGDGDDDPQLSWVASSPSSKDVASPT 116
E Y C+ C + F + + LT H+ ++C G S ++ V P
Sbjct: 982 EKPYKCEECGKSFSTFSILTKHKVIHTGEKPYKCEECGKAYKWSSTLSYHKKIHTVEKPY 1041
Query: 117 QMIGDGCDLGL-------GEEEGGTGLP-YPCQFCDKSFIRLSYLKRHEQIHSDKLPFKC 168
+ + C G + TG Y C+ C K++ S L+ H++IH+ + P+KC
Sbjct: 1042 KC--EECGKGFVMFSILAKHKVIHTGEKLYKCEECGKAYKWPSTLRYHKKIHTGEKPYKC 1099
Query: 169 TYCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAFS----RSDHLKIHL---------KT 215
C + F +H +HTG+K Y C EC AFS S H KIH K
Sbjct: 1100 EECGKAFSTFSILTKHKVIHTGEKPYKCEECGKAFSWLSVFSKHKKIHTGVPNPPTHKKI 1159
Query: 216 HSSSKPFK 223
H+ K +K
Sbjct: 1160 HAGEKLYK 1167
>gi|210031219 zinc finger protein 845 [Homo sapiens]
Length = 970
Score = 231 bits (589), Expect = 3e-60
Identities = 214/866 (24%), Positives = 316/866 (36%), Gaps = 163/866 (18%)
Query: 138 YPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCH 197
Y C C K F + YL H + H+ K P+KC C + F + + H +LHTG+K Y C
Sbjct: 243 YKCDVCGKVFNQKRYLACHRRCHTGKKPYKCNDCGKTFSQELTLTCHHRLHTGEKHYKCS 302
Query: 198 ECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEKE 257
EC FSR+ L IH H+ K +KC C + FS TS L H + H K
Sbjct: 303 ECGKTFSRNSALVIHKAIHTGEKSYKCNECGKTFSQTSYLVYHRRLHTGEK--------- 353
Query: 258 AKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQA 317
+ C+ C+ FS LE+H R EK +C C F +++L H
Sbjct: 354 ----PYKCEECDKAFSFKSNLERH---RKIHTGEK-PYKCNECSRTFSRKSSLTRHRRLH 405
Query: 318 HANQKHKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDSSAS 377
+ +KC C + FS + + H H T +
Sbjct: 406 TGEKPYKCNDCGKTFSQMSSLVYHRRLH-------------------------TGEKPYK 440
Query: 378 VERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHADKP 437
E S L +++ + Y C C K F+ + L H + +KP
Sbjct: 441 CEECDEAFSFKSNLERHRRIHTG-----EKPYKCNDCGK-TFSQTSSLVYHRRLHTGEKP 494
Query: 438 QQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINSLQE 497
+ C+ C ++ NL H R +H + CN C + F+ +SL
Sbjct: 495 ---YKCEECDEAFSFKSNLERH-RIIHTGE----------KLYKCNECGKTFSRKSSLTR 540
Query: 498 HIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPTQ 557
H R+ G + CN+C F +S+L H QA +G
Sbjct: 541 HCRL---------HTGEKPYQCNECGKAFRGQSALIYH--QAIHGIG------------- 576
Query: 558 SFMEVYSCPYCTNSPIFGSILKLTKHIKEN----------------HKNIPLAHSKKSKA 601
++Y C C +F + + H + + H++ H +
Sbjct: 577 ---KLYKCNDC--HQVFSNATTIANHWRIHNEERSYKCNRCGKFFRHRSYLAVHWRTHSG 631
Query: 602 EQSPVSSDVEVSSPKRQRLSASANSISNGE--YPCNQCDLKFSNFESFQTHLKLHLELLL 659
E+ + + + + L I GE Y CN+C FS H +LH
Sbjct: 632 EKPYKCEECDEAFSFKSNLQRH-RRIHTGEKPYRCNECGKTFSRKSYLTCHRRLHTG--E 688
Query: 660 RKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVL 719
+ C +C + F +L+ H +H T Y C C K FS L H L +HT
Sbjct: 689 KPYKCNECGKTFGRNSALIIHKAIH--TGEKPYKCNECGKAFSQKSSLTCH-LRLHTGEK 745
Query: 720 -YHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPA 778
Y C C +VF K S++ H + H+ EK Y+C C+ F +++ L +H+ +
Sbjct: 746 PYKCEECDKVFSRKSSLEKHRRI-HTGEKP-YKCKVCDKAFGRDSHL---AQHTRIHTGE 800
Query: 779 KAHKCIFCGETFSTEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHLREKHCVFDAA 836
K +KC CG+ F L H HS K Y C C K F LE H
Sbjct: 801 KPYKCNECGKNFRHNSALVIHKAIHSGEKPYKCNECGKTFRHNSALEIH----------- 849
Query: 837 TENGTANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYT 896
G P + G + + H + E Y C+ CG +
Sbjct: 850 --KAIHTGEKPYKCSEC------GKVFNRKANLSRHHR----LHTGEKPYKCNKCGKVFN 897
Query: 897 MEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPA 956
+ L H H I GE +KCN C +TF + L H H G
Sbjct: 898 QQAHLACH----HRIHTGEK------------PYKCNECGKTFRHNSVLVIHKTIHTG-E 940
Query: 957 KHYMCPICGERFPSLLTLTEHKVTHS 982
K Y C CG+ F L H H+
Sbjct: 941 KPYKCNECGKVFNRKAKLARHHRIHT 966
Score = 224 bits (570), Expect = 5e-58
Identities = 209/826 (25%), Positives = 306/826 (37%), Gaps = 166/826 (20%)
Query: 138 YPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCH 197
Y C C K+F R S L H+ IH+ + +KC C + F H +LHTG+K Y C
Sbjct: 299 YKCSECGKTFSRNSALVIHKAIHTGEKSYKCNECGKTFSQTSYLVYHRRLHTGEKPYKCE 358
Query: 198 ECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEKE 257
EC+ AFS +L+ H K H+ KP+KC C R FS SSL H + H K
Sbjct: 359 ECDKAFSFKSNLERHRKIHTGEKPYKCNECSRTFSRKSSLTRHRRLHTGEKP-------- 410
Query: 258 AKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQA 317
+ C+ C TFSQ L H R EK +C C E F ++ L H +
Sbjct: 411 -----YKCNDCGKTFSQMSSLVYH---RRLHTGEKP-YKCEECDEAFSFKSNLERH-RRI 460
Query: 318 HANQK-HKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDSSA 376
H +K +KC C + FS + H H + P
Sbjct: 461 HTGEKPYKCNDCGKTFSQTSSLVYHRRLH----------------------TGEKPYKCE 498
Query: 377 SVERGSTPDSTLKPLR----GQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTI 432
+ + S L+ R G+K +Y C C K F+ + L H +
Sbjct: 499 ECDEAFSFKSNLERHRIIHTGEK------------LYKCNECGKT-FSRKSSLTRHCRLH 545
Query: 433 HADKPQQSHTCQICLDSMPTL-YNLNEH-VRKLHKNHAYPVMQFGNISAFHCNYCPEMFA 490
+KP Q + C L Y+ H + KL+K CN C ++F+
Sbjct: 546 TGEKPYQCNECGKAFRGQSALIYHQAIHGIGKLYK----------------CNDCHQVFS 589
Query: 491 DINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLES 550
+ ++ H R+ + ++ CN+C F S L H +
Sbjct: 590 NATTIANHWRIHN---------EERSYKCNRCGKFFRHRSYLAVHWR------------- 627
Query: 551 PVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDV 610
T S + Y C C + F S L+ + I K K+ + +S ++
Sbjct: 628 -----THSGEKPYKCEECDEAFSFKSNLQRHRRIHTGEKPYRCNECGKTFSRKSYLTCHR 682
Query: 611 EVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKED 670
+ + ++ Y CN+C F + H +H + C +C +
Sbjct: 683 RLHTGEKP-------------YKCNECGKTFGRNSALIIHKAIHTGE--KPYKCNECGKA 727
Query: 671 FDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFD 730
F + SL HL +H T Y CE CDK FS L+KH Y C +C + F
Sbjct: 728 FSQKSSLTCHLRLH--TGEKPYKCEECDKVFSRKSSLEKHRRIHTGEKPYKCKVCDKAFG 785
Query: 731 SKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETF 790
+ H + H+ EK Y+C C +FR + L +H K H G K +KC CG+TF
Sbjct: 786 RDSHLAQHTRI-HTGEKP-YKCNECGKNFRHNSALVIH-KAIHSGE--KPYKCNECGKTF 840
Query: 791 STEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPM 848
L+ H H+ K Y C C K F+ L +H R G P
Sbjct: 841 RHNSALEIHKAIHTGEKPYKCSECGKVFNRKANLSRHHR-------------LHTGEKPY 887
Query: 849 ATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRD 908
K Q +H A + E Y C+ CG + +L H+
Sbjct: 888 KCNKCGKVFNQ----------QAHLACHHRIHTGEKPYKCNECGKTFRHNSVLVIHK--- 934
Query: 909 HNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRG 954
I GE +KCN C + F + L H + H G
Sbjct: 935 -TIHTGEKP------------YKCNECGKVFNRKAKLARHHRIHTG 967
Score = 221 bits (564), Expect = 3e-57
Identities = 206/784 (26%), Positives = 304/784 (38%), Gaps = 136/784 (17%)
Query: 64 ESIYTCDHCQQDFESLADLTDHRA-------HRCPGDGDDDPQLSWVASSPSSKDVASPT 116
E Y C C + F + L H+A ++C G Q S++
Sbjct: 296 EKHYKCSECGKTFSRNSALVIHKAIHTGEKSYKCNECGKTFSQTSYLVYHRR-------- 347
Query: 117 QMIGDGCDLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFK 176
L GE+ PY C+ CDK+F S L+RH +IH+ + P+KC CSR F
Sbjct: 348 --------LHTGEK------PYKCEECDKAFSFKSNLERHRKIHTGEKPYKCNECSRTFS 393
Query: 177 HKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSS 236
K S RH +LHTG+K Y C++C FS+ L H + H+ KP+KC C FS S+
Sbjct: 394 RKSSLTRHRRLHTGEKPYKCNDCGKTFSQMSSLVYHRRLHTGEKPYKCEECDEAFSFKSN 453
Query: 237 LQSHMQAHKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQ 296
L+ H + H K + C+ C TFSQT L H R EK +
Sbjct: 454 LERHRRIHTGEKP-------------YKCNDCGKTFSQTSSLVYH---RRLHTGEKP-YK 496
Query: 297 CIHCPEVFVDENTLLAHIHQAHANQK-HKCPMCPEQFSSVEGV--YCHLDSHRQPDSSNH 353
C C E F ++ L H H +K +KC C + FS + +C L + +P N
Sbjct: 497 CEECDEAFSFKSNLERH-RIIHTGEKLYKCNECGKTFSRKSSLTRHCRLHTGEKPYQCNE 555
Query: 354 SVSPDPVLGSVASMSSATPDSSASVERGSTPD--------STLKPLRGQKKMRDDGQGWT 405
G SA A G S + ++ ++ +
Sbjct: 556 C-------GKAFRGQSALIYHQAIHGIGKLYKCNDCHQVFSNATTIANHWRIHNEERS-- 606
Query: 406 KVVYSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHK 465
Y C C K F + L +H +T +KP + C+ C ++ NL H R++H
Sbjct: 607 ---YKCNRCGKF-FRHRSYLAVHWRTHSGEKP---YKCEECDEAFSFKSNLQRH-RRIHT 658
Query: 466 NHAYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMG 525
+ CN C + F+ + L H R+ G + CN+C
Sbjct: 659 GE----------KPYRCNECGKTFSRKSYLTCHRRLH---------TGEKPYKCNECGKT 699
Query: 526 FLTESSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIK 585
F S+L H + H E P Y C C + F LT H++
Sbjct: 700 FGRNSALIIH-KAIHTG------EKP-----------YKCNECGKA--FSQKSSLTCHLR 739
Query: 586 ENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFE 645
+ K K E+ + S K +R+ Y C CD F
Sbjct: 740 LH------TGEKPYKCEECDKVFSRKSSLEKHRRIHTGEKP-----YKCKVCDKAFGRDS 788
Query: 646 SFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVD 705
H ++H + C +C ++F +L+ H +H + Y C C K F
Sbjct: 789 HLAQHTRIHTGE--KPYKCNECGKNFRHNSALVIHKAIH--SGEKPYKCNECGKTFRHNS 844
Query: 706 DLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADL 765
L+ H Y C+ C +VF+ K ++ H + H+ EK Y+C C F ++A L
Sbjct: 845 ALEIHKAIHTGEKPYKCSECGKVFNRKANLSRHHRL-HTGEKP-YKCNKCGKVFNQQAHL 902
Query: 766 QVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHITTHS--KKYNCKFCSKAFHAIILLE 823
H + H G K +KC CG+TF L H T H+ K Y C C K F+ L
Sbjct: 903 ACHHR-IHTGE--KPYKCNECGKTFRHNSVLVIHKTIHTGEKPYKCNECGKVFNRKAKLA 959
Query: 824 KHLR 827
+H R
Sbjct: 960 RHHR 963
Score = 171 bits (432), Expect = 5e-42
Identities = 200/827 (24%), Positives = 308/827 (37%), Gaps = 137/827 (16%)
Query: 480 FHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLT------ 533
+ C+ C ++F L H R G + CN C F E +LT
Sbjct: 243 YKCDVCGKVFNQKRYLACHRRCH---------TGKKPYKCNDCGKTFSQELTLTCHHRLH 293
Query: 534 ---EHIQQAHCSVGSAKLESPVVQPT-QSFMEVYSCPYCTNSPIFGSILKLTKHIKENHK 589
+H + + C ++ + V+ + + Y C C G T ++ H+
Sbjct: 294 TGEKHYKCSECGKTFSRNSALVIHKAIHTGEKSYKCNEC------GKTFSQTSYLVY-HR 346
Query: 590 NIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSISNGE--YPCNQCDLKFSNFESF 647
+ K K E+ + + S+ +R R I GE Y CN+C FS S
Sbjct: 347 RLHTGE-KPYKCEECDKAFSFK-SNLERHR------KIHTGEKPYKCNECSRTFSRKSSL 398
Query: 648 QTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDL 707
H +LH + C C + F SL+ H +H T Y CE CD+ FS +L
Sbjct: 399 TRHRRLHTGE--KPYKCNDCGKTFSQMSSLVYHRRLH--TGEKPYKCEECDEAFSFKSNL 454
Query: 708 QKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQV 767
++H Y C C + F S+ H + H+ EK Y+C C+ F +++L+
Sbjct: 455 ERHRRIHTGEKPYKCNDCGKTFSQTSSLVYHRRL-HTGEKP-YKCEECDEAFSFKSNLER 512
Query: 768 HVKHSHLGNPAKAHKCIFCGETFSTEVEL--QCHITTHSKKYNCKFCSKAFHAIILLEKH 825
H + H G K +KC CG+TFS + L C + T K Y C C KAF L H
Sbjct: 513 H-RIIHTGE--KLYKCNECGKTFSRKSSLTRHCRLHTGEKPYQCNECGKAFRGQSALIYH 569
Query: 826 -----------LREKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAPNSHEA 874
+ H VF AT AN +++ + G ++ S+ A
Sbjct: 570 QAIHGIGKLYKCNDCHQVFSNATT--IANHWRIHNEERSYKCNRCGKFFRH----RSYLA 623
Query: 875 SEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNV 934
+ E Y C+ C A++ + LQ HR I GE ++CN
Sbjct: 624 VHWRTHSGEKPYKCEECDEAFSFKSNLQRHR----RIHTGEKP------------YRCNE 667
Query: 935 CSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICK 994
C +TF ++ L H + H G K Y C CG+ F L HK H+ C C
Sbjct: 668 CGKTFSRKSYLTCHRRLHTGE-KPYKCNECGKTFGRNSALIIHKAIHTGEKPY-KCNECG 725
Query: 995 MPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASS 1054
+ H ++H + ++C C + + L+ H H
Sbjct: 726 KAFSQKSSLTCHLRLHTGEKP----YKCEECDKVFSRKSSLEKHRRIHTG---------- 771
Query: 1055 PNGQGLQKLYKCALCLKEFRSKQDLV---KLDVNGLPYGLCAGCMARSANGQVGGLAPP- 1110
+K YKC +C K F L ++ PY C C + +
Sbjct: 772 ------EKPYKCKVCDKAFGRDSHLAQHTRIHTGEKPYK-CNECGKNFRHNSALVIHKAI 824
Query: 1111 EPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGPRKGTQTSPVPRKKTYQC 1170
++P +C EC F LE H K T +K Y+C
Sbjct: 825 HSGEKP---YKCNECGKTFRHNSALEIH----------------KAIHTG----EKPYKC 861
Query: 1171 IKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFK 1230
+C F + + H H E+ ++C C ++F+ A L CH H+ E +K
Sbjct: 862 SECGKVFNRKANLSRHHRLHTGEKP--YKCNKCGKVFNQQAHLACHHRIHTGE---KPYK 916
Query: 1231 CPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNH 1277
C C F + L H +H E K Y C++C + F + +L H
Sbjct: 917 CNECGKTFRHNSVLVIH-KTIHTGE-KPYKCNECGKVFNRKAKLARH 961
Score = 164 bits (414), Expect = 7e-40
Identities = 161/653 (24%), Positives = 237/653 (36%), Gaps = 135/653 (20%)
Query: 632 YPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTH 691
Y CN C FS + H +LH + C +C + F +L+ H +H T
Sbjct: 271 YKCNDCGKTFSQELTLTCHHRLHTGE--KHYKCSECGKTFSRNSALVIHKAIH--TGEKS 326
Query: 692 YVCESCDKQFSSVDDLQKHLLDMHTFVL-YHCTLCQEVFDSKVSIQVHLAVKHSNEKKMY 750
Y C C K FS L H +HT Y C C + F K +++ H + H+ EK Y
Sbjct: 327 YKCNECGKTFSQTSYLVYHRR-LHTGEKPYKCEECDKAFSFKSNLERHRKI-HTGEKP-Y 383
Query: 751 RCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHITTHS--KKYN 808
+C C+ F +++ L +H L K +KC CG+TFS L H H+ K Y
Sbjct: 384 KCNECSRTFSRKSSL---TRHRRLHTGEKPYKCNDCGKTFSQMSSLVYHRRLHTGEKPYK 440
Query: 809 CKFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEA 868
C+ C +AF LE+H R G P G +
Sbjct: 441 CEECDEAFSFKSNLERHRR-------------IHTGEKPYKCNDC------GKTFSQTSS 481
Query: 869 PNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKG 928
H + E Y C+ C A++ + L+ HR+ I GE
Sbjct: 482 LVYHRR----LHTGEKPYKCEECDEAFSFKSNLERHRI----IHTGEK------------ 521
Query: 929 SHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTG 988
+KCN C +TF ++ L H + H G K Y C CG+ F L H+ H
Sbjct: 522 LYKCNECGKTFSRKSSLTRHCRLHTGE-KPYQCNECGKAFRGQSALIYHQAIHGIG-KLY 579
Query: 989 TCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAG 1048
C C + H ++H + R+ ++C C + L +H H
Sbjct: 580 KCNDCHQVFSNATTIANHWRIHNEERS----YKCNRCGKFFRHRSYLAVHWRTHSG---- 631
Query: 1049 SSAASSPNGQGLQKLYKCALCLKEFRSKQDLVK---LDVNGLPYGLCAGCMARSANGQVG 1105
+K YKC C + F K +L + + PY
Sbjct: 632 ------------EKPYKCEECDEAFSFKSNLQRHRRIHTGEKPY---------------- 663
Query: 1106 GLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGPRKGTQTSPVPRK 1165
RC EC F L H ++ +
Sbjct: 664 ---------------RCNECGKTFSRKSYLTCHRRLHTGE-------------------- 688
Query: 1166 KTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGM 1225
K Y+C +C TF + IH A H E+ ++C C + F + L CHL H+ E
Sbjct: 689 KPYKCNECGKTFGRNSALIIHKAIHTGEKP--YKCNECGKAFSQKSSLTCHLRLHTGE-- 744
Query: 1226 GGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNHT 1278
+KC C VF + + L++H +H E K Y C C + F + L HT
Sbjct: 745 -KPYKCEECDKVFSRKSSLEKH-RRIHTGE-KPYKCKVCDKAFGRDSHLAQHT 794
Score = 126 bits (316), Expect = 2e-28
Identities = 128/532 (24%), Positives = 190/532 (35%), Gaps = 121/532 (22%)
Query: 748 KMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHITTHS--K 805
K Y+C C F ++ L H + H G K +KC CG+TFS E+ L CH H+ K
Sbjct: 241 KQYKCDVCGKVFNQKRYLACH-RRCHTGK--KPYKCNDCGKTFSQELTLTCHHRLHTGEK 297
Query: 806 KYNCKFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKN 865
Y C C K F R V A G +K+ + G
Sbjct: 298 HYKCSECGKTFS---------RNSALVIHKAIHTG----------EKSYKCNECGKTFSQ 338
Query: 866 PEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEF 925
S+ + E Y C+ C A++ + L+ HR I GE
Sbjct: 339 ----TSYLVYHRRLHTGEKPYKCEECDKAFSFKSNLERHR----KIHTGEKP-------- 382
Query: 926 IKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSL 985
+KCN CSRTF ++ L H + H G K Y C CG+ F + +L H+ H+
Sbjct: 383 ----YKCNECSRTFSRKSSLTRHRRLHTGE-KPYKCNDCGKTFSQMSSLVYHRRLHTGEK 437
Query: 986 DTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQK 1045
C C + H ++H + ++C C +T + T L H H
Sbjct: 438 PY-KCEECDEAFSFKSNLERHRRIHTGEKP----YKCNDCGKTFSQTSSLVYHRRLHTG- 491
Query: 1046 LAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLVKLDVNGLPYGLCAGCMARSANGQVG 1105
+K YKC C + F K +L + + L
Sbjct: 492 ---------------EKPYKCEECDEAFSFKSNLERHRIIHTGEKL-------------- 522
Query: 1106 GLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGPRKGTQTSPVPRK 1165
+C EC F L H ++ +
Sbjct: 523 --------------YKCNECGKTFSRKSSLTRHCRLHTGE-------------------- 548
Query: 1166 KTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGM 1225
K YQC +C F + + H A H I G ++C C+Q+F + + H H+ E
Sbjct: 549 KPYQCNECGKAFRGQSALIYHQAIHGI--GKLYKCNDCHQVFSNATTIANHWRIHNEER- 605
Query: 1226 GGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNH 1277
++KC C F + L H + H E K Y C +C + F F++ LQ H
Sbjct: 606 --SYKCNRCGKFFRHRSYLAVH-WRTHSGE-KPYKCEECDEAFSFKSNLQRH 653
Score = 122 bits (307), Expect = 2e-27
Identities = 143/567 (25%), Positives = 222/567 (39%), Gaps = 77/567 (13%)
Query: 747 KKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHITTHS-- 804
+K ++C F + L+ H + HLG AK +KC CG+ F+ + L CH H+
Sbjct: 212 EKSFQCNESGKAFNYSSVLRKH-QIIHLG--AKQYKCDVCGKVFNQKRYLACHRRCHTGK 268
Query: 805 KKYNCKFCSKAFHAIILLEKHLR----EKH--CVFDAATENGTANGVPPMATKKAEPADL 858
K Y C C K F + L H R EKH C T + + V A E +
Sbjct: 269 KPYKCNDCGKTFSQELTLTCHHRLHTGEKHYKCSECGKTFSRNSALVIHKAIHTGEKSYK 328
Query: 859 QGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDG 918
K + S+ + E Y C+ C A++ + L+ HR I GE
Sbjct: 329 CNECGKT-FSQTSYLVYHRRLHTGEKPYKCEECDKAFSFKSNLERHR----KIHTGEK-- 381
Query: 919 SRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHK 978
+KCN CSRTF ++ L H + H G K Y C CG+ F + +L H+
Sbjct: 382 ----------PYKCNECSRTFSRKSSLTRHRRLHTG-EKPYKCNDCGKTFSQMSSLVYHR 430
Query: 979 VTHSKSLDTGTCRICKMPLQSEE-----EFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTL 1033
H TG + P + EE F + + H + ++C C +T + T
Sbjct: 431 RLH-----TG-----EKPYKCEECDEAFSFKSNLERHRRIHTGEKPYKCNDCGKTFSQTS 480
Query: 1034 ELKIHGTFHMQKL--------AGSSAASSPNGQGL----QKLYKCALCLKEFRSKQDLV- 1080
L H H + S S+ + +KLYKC C K F K L
Sbjct: 481 SLVYHRRLHTGEKPYKCEECDEAFSFKSNLERHRIIHTGEKLYKCNECGKTFSRKSSLTR 540
Query: 1081 --KLDVNGLPYGLCAGCMARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESH 1138
+L PY C C ++ GQ L + +C +C F +A + +H
Sbjct: 541 HCRLHTGEKPY-QCNEC-GKAFRGQ-SALIYHQAIHGIGKLYKCNDCHQVFSNATTIANH 597
Query: 1139 MQVDHRDLTPETSGPRK--------GTQTSPVPRKKTYQCIKCQMTFENEREIQIHVANH 1190
++ + + + + + K +K Y+C +C F + +Q H H
Sbjct: 598 WRIHNEERSYKCNRCGKFFRHRSYLAVHWRTHSGEKPYKCEECDEAFSFKSNLQRHRRIH 657
Query: 1191 MIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFA 1250
E+ + C C + F + L CH H+ E +KC C F + + L H A
Sbjct: 658 TGEK--PYRCNECGKTFSRKSYLTCHRRLHTGE---KPYKCNECGKTFGRNSALIIH-KA 711
Query: 1251 VHGQEDKIYDCSQCPQKFFFQTELQNH 1277
+H E K Y C++C + F ++ L H
Sbjct: 712 IHTGE-KPYKCNECGKAFSQKSSLTCH 737
Score = 112 bits (280), Expect = 2e-24
Identities = 73/260 (28%), Positives = 109/260 (41%), Gaps = 33/260 (12%)
Query: 64 ESIYTCDHCQQDFESLADLTDHRAHRCPGDGDDDPQLSWVASSPSSKDVASPTQMIGDGC 123
E Y C+ C + F + L HR + P V +D +
Sbjct: 744 EKPYKCEECDKVFSRKSSLEKHRRIHT----GEKPYKCKVCDKAFGRD-----SHLAQHT 794
Query: 124 DLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDR 183
+ GE+ PY C C K+F S L H+ IHS + P+KC C + F+H + +
Sbjct: 795 RIHTGEK------PYKCNECGKNFRHNSALVIHKAIHSGEKPYKCNECGKTFRHNSALEI 848
Query: 184 HIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQA 243
H +HTG+K Y C EC F+R +L H + H+ KP+KC C + F+ + L H +
Sbjct: 849 HKAIHTGEKPYKCSECGKVFNRKANLSRHHRLHTGEKPYKCNKCGKVFNQQAHLACHHRI 908
Query: 244 HKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEV 303
H K + C+ C TF L H T H + + +C C +V
Sbjct: 909 HTGEK-------------PYKCNECGKTFRHNSVLVIH-KTIH---TGEKPYKCNECGKV 951
Query: 304 FVDENTLLAHIHQAHANQKH 323
F + LA H+ H +KH
Sbjct: 952 F-NRKAKLARHHRIHTGKKH 970
>gi|122937213 zinc finger protein 99 [Homo sapiens]
Length = 1036
Score = 221 bits (562), Expect = 5e-57
Identities = 222/924 (24%), Positives = 342/924 (37%), Gaps = 162/924 (17%)
Query: 137 PYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 196
PY C+ C K+F + S+L RH+ IH+ + P+KC C + F H + +H +HTG K Y C
Sbjct: 193 PYKCEECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSALRKHQIIHTGKKPYKC 252
Query: 197 HECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEK 256
EC AFS+S L+ H H+ KP+K C + FS+ S+L+ H H K
Sbjct: 253 EECGKAFSQSSTLRKHEIIHTEEKPYKYEECGKAFSNLSALRKHEIIHTGQKP------- 305
Query: 257 EAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQ 316
+ C+ C F + +L H + + + +C C + F + L H
Sbjct: 306 ------YKCEECGKAFKWSSKLTVHKVIH----TAEKPCKCEECGKAFKRFSALRKHKII 355
Query: 317 AHANQKHKCPMCPEQFSSVEGVYCHLDSHR-------QPDSSNHSVSPDPVLGSVASMSS 369
Q +KC C + FS+ + H H + S + V M
Sbjct: 356 HTGKQPYKCEECSKAFSNFSALRKHEIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHME- 414
Query: 370 ATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHL 429
+ E LR K + K Y C C K FN+ + L H
Sbjct: 415 ---EKPCKCEECGKAFKHFSALRKHKIIHTG-----KKPYKCEECGKA-FNNSSTLMKH- 464
Query: 430 KTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMF 489
K IH K + + C+ C + +L H + +H + C C + F
Sbjct: 465 KIIHTGK--KPYKCEECGKAFKQSSHLTRH-KAIHTGE----------KPYKCEECGKAF 511
Query: 490 ADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEH---------IQQAH 540
++L++H ++ H G + C +C F S+L +H +
Sbjct: 512 NHFSALRKH-QIIHTG--------KKPYKCEECGKAFSQSSTLRKHEIIHTGEKPYKCEE 562
Query: 541 CSVG---SAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSK 597
C S+ L V T+ + Y C C + F L KH + H+
Sbjct: 563 CGKAFKWSSHLTRHKVIHTEE--KPYKCEECGKA--FNHFSALRKH--------KIIHTG 610
Query: 598 KSKAEQSPVSSDVEVSSPKRQRLSASANSISNGE--YPCNQCDLKFSNFESFQTHLKLHL 655
K + SS R+ I GE Y C +C F H +H
Sbjct: 611 KKPYKCEECGKAFSQSSTLRKH-----EIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHT 665
Query: 656 ELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKH----- 710
K C +C + F +L +H +H T Y CE C K F++ L+KH
Sbjct: 666 AEKPCK--CEECGKAFKHFSALRKHKIIH--TGKKPYKCEECGKAFNNSSTLRKHEIIHT 721
Query: 711 ----------LLDMHTFVL-----YHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTAC 755
L H + Y C C + F++ +++ H + KK Y+C C
Sbjct: 722 GEKSYKCEECALRKHEIIHTGKKPYKCEECGKAFNNSSTLRKHKIIYTG--KKPYKCEEC 779
Query: 756 NWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCH--ITTHSKKYNCKFCS 813
F++ + L H K H G K +KC CG+ F+ L+ H I T K Y C+ C
Sbjct: 780 GKAFKQSSHLTRH-KAVHTGE--KPYKCGECGKAFNNSSTLKKHKLIHTREKSYKCEECG 836
Query: 814 KAFHAIILLEKH---------LREKHCVFDAATENGTA--------NGVPPMATKKAEPA 856
KAF L KH + + C A N + G P ++
Sbjct: 837 KAFSNFSALRKHKIIHTGEKPYKCEECECGKAFNNSSTLMKHKIIHTGEKPYKCEECGKG 896
Query: 857 D------LQGMLLKNPEAP------------NSHEASEDDVDASEPMYGCDICGAAYTME 898
++ ++ E P +SH + E Y C+ G A++
Sbjct: 897 FNNFSTLMKHKIIHTGEKPYKCEECGKAFKQSSHLTKHKSIHTGEKPYKCEERGKAFSHF 956
Query: 899 VLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKH 958
L HR+ +P K E + +KC C + F + L +H H G K
Sbjct: 957 SRLTKHRIIHTGKKP-------YKCEECEKPYKCEECGKAFNQSSHLTQHKTIHTG-GKT 1008
Query: 959 YMCPICGERFPSLLTLTEHKVTHS 982
Y C CG+ F L LT+HK+ H+
Sbjct: 1009 YKCEECGKAFNHLSALTKHKIIHT 1032
Score = 174 bits (440), Expect = 6e-43
Identities = 249/1132 (21%), Positives = 380/1132 (33%), Gaps = 267/1132 (23%)
Query: 171 CSRLFKHKRSRDRHIKLH-----TGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCT 225
C + + K + + KL+ T K + C++ F + + + H+ KP+KC
Sbjct: 138 CESVNEGKMHEEAYNKLNQCWTTTQGKIFQCNKYVKVFHKYSNSNRYKIIHTGKKPYKCE 197
Query: 226 VCKRGFSSTSSLQSHMQAHKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTR 285
C + F +S L H H K + C+ C F+ L KH
Sbjct: 198 ECGKAFKQSSHLTRHKAIHTGEKP-------------YKCEECGKAFNHFSALRKH---- 240
Query: 286 HPQLSEKADLQCIHCPEVFVDENTLLAHIHQAHANQKHKCPMCPEQFSSVEGVYCHLDSH 345
Q IH + +KC C + FS + H H
Sbjct: 241 ----------QIIHT------------------GKKPYKCEECGKAFSQSSTLRKHEIIH 272
Query: 346 RQPDSSNHSVSPDPVLGSVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWT 405
T + E S L LR + ++ GQ
Sbjct: 273 -------------------------TEEKPYKYEECGKAFSNLSALR-KHEIIHTGQK-- 304
Query: 406 KVVYSCPYCSKRDFNSLAVLEIHLKTIH-ADKPQQSHTCQICLDSMPTLYNLNEHVRKLH 464
Y C C K F + L +H K IH A+KP + C+ C + L +H
Sbjct: 305 --PYKCEECGKA-FKWSSKLTVH-KVIHTAEKPCK---CEECGKAFKRFSALRKH----- 352
Query: 465 KNHAYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSM 524
++ G + C C + F++ ++L++H + H G + C +C
Sbjct: 353 -----KIIHTGK-QPYKCEECSKAFSNFSALRKH-EIIHTG--------EKPYKCEECGK 397
Query: 525 GFLTESSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHI 584
F S LT H + H K C C + S L+ K I
Sbjct: 398 AFKWSSKLTVH-KVIHMEEKPCK-----------------CEECGKAFKHFSALRKHKII 439
Query: 585 KENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNF 644
K K+ S + + + K+ Y C +C F
Sbjct: 440 HTGKKPYKCEECGKAFNNSSTLMKHKIIHTGKKP-------------YKCEECGKAFKQS 486
Query: 645 ESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSV 704
H +H + C +C + F+ +L +H +H T Y CE C K FS
Sbjct: 487 SHLTRHKAIHTGE--KPYKCEECGKAFNHFSALRKHQIIH--TGKKPYKCEECGKAFSQS 542
Query: 705 DDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEAD 764
L+KH + Y C C + F + H + E+K Y+C C F +
Sbjct: 543 STLRKHEIIHTGEKPYKCEECGKAFKWSSHLTRHKVIH--TEEKPYKCEECGKAFNHFSA 600
Query: 765 LQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCH--ITTHSKKYNCKFCSKAF------ 816
L+ H K H G K +KC CG+ FS L+ H I T K Y C+ C KAF
Sbjct: 601 LRKH-KIIHTGK--KPYKCEECGKAFSQSSTLRKHEIIHTGEKPYKCEECGKAFKWSSKL 657
Query: 817 --HAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAPNSHEA 874
H +I H EK C K E G K+ A H+
Sbjct: 658 TVHKVI----HTAEKPC--------------------KCEEC---GKAFKHFSALRKHKI 690
Query: 875 SEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNV 934
+ + Y C+ CG A+ L+ H + I GE S+KC
Sbjct: 691 ----IHTGKKPYKCEECGKAFNNSSTLRKHEI----IHTGEK------------SYKCEE 730
Query: 935 CSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICK 994
C+ LR+H H G K Y C CG+ F + TL +HK+ ++ C C
Sbjct: 731 CA--------LRKHEIIHTGK-KPYKCEECGKAFNNSSTLRKHKIIYTGKKPY-KCEECG 780
Query: 995 MPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASS 1054
+ H +H + ++C C + ++ LK H H +
Sbjct: 781 KAFKQSSHLTRHKAVHTGEKP----YKCGECGKAFNNSSTLKKHKLIHTR---------- 826
Query: 1055 PNGQGLQKLYKCALCLKEFRSKQDLVK---LDVNGLPYGLCAGCMARSANGQVGGLAPPE 1111
+K YKC C K F + L K + PY C C A L +
Sbjct: 827 ------EKSYKCEECGKAFSNFSALRKHKIIHTGEKPYK-CEECECGKAFNNSSTLMKHK 879
Query: 1112 PADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGPRKGTQTSPVPRKKTYQCI 1171
+C EC F + L H ++ H +K Y+C
Sbjct: 880 IIHTGEKPYKCEECGKGFNNFSTLMKH-KIIHTG-------------------EKPYKCE 919
Query: 1172 KCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHS------FEGM 1225
+C F+ + H + H E+ ++C+ + F ++L H I H+ E
Sbjct: 920 ECGKAFKQSSHLTKHKSIHTGEKP--YKCEERGKAFSHFSRLTKHRIIHTGKKPYKCEEC 977
Query: 1226 GGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNH 1277
+KC C F Q++ L QH G K Y C +C + F + L H
Sbjct: 978 EKPYKCEECGKAFNQSSHLTQHKTIHTG--GKTYKCEECGKAFNHLSALTKH 1027
Score = 162 bits (409), Expect = 3e-39
Identities = 179/753 (23%), Positives = 282/753 (37%), Gaps = 141/753 (18%)
Query: 575 GSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSISNGE--Y 632
G I + K++K HK K + P + + K+ +I GE Y
Sbjct: 163 GKIFQCNKYVKVFHKYSNSNRYKIIHTGKKPYKCEECGKAFKQSSHLTRHKAIHTGEKPY 222
Query: 633 PCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHY 692
C +C F++F + + H +H + C +C + F +L +H +H T Y
Sbjct: 223 KCEECGKAFNHFSALRKHQIIHTGK--KPYKCEECGKAFSQSSTLRKHEIIH--TEEKPY 278
Query: 693 VCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRC 752
E C K FS++ L+KH + Y C C + F + VH + H+ EK +C
Sbjct: 279 KYEECGKAFSNLSALRKHEIIHTGQKPYKCEECGKAFKWSSKLTVHKVI-HTAEKPC-KC 336
Query: 753 TACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCH--ITTHSKKYNCK 810
C F++ + L+ H K H G + +KC C + FS L+ H I T K Y C+
Sbjct: 337 EECGKAFKRFSALRKH-KIIHTGK--QPYKCEECSKAFSNFSALRKHEIIHTGEKPYKCE 393
Query: 811 FCSKAF--------HAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQGML 862
C KAF H +I H+ EK C K E G
Sbjct: 394 ECGKAFKWSSKLTVHKVI----HMEEKPC--------------------KCEEC---GKA 426
Query: 863 LKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKK 922
K+ A H+ + + Y C+ CG A+ L H++ +P + + K
Sbjct: 427 FKHFSALRKHKI----IHTGKKPYKCEECGKAFNNSSTLMKHKIIHTGKKPYKCEECGKA 482
Query: 923 AEFIKGSH--------------KCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERF 968
F + SH KC C + F + LR+H H G K Y C CG+ F
Sbjct: 483 --FKQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSALRKHQIIHTGK-KPYKCEECGKAF 539
Query: 969 PSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQT 1028
TL +H++ H+ C C + H +H + + ++C C +
Sbjct: 540 SQSSTLRKHEIIHTGEKPY-KCEECGKAFKWSSHLTRHKVIHTEEKP----YKCEECGKA 594
Query: 1029 VTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLVKLDV---N 1085
L+ H H K K YKC C K F L K ++
Sbjct: 595 FNHFSALRKHKIIHTGK----------------KPYKCEECGKAFSQSSTLRKHEIIHTG 638
Query: 1086 GLPYGLCAGC-MARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHR 1144
PY C C A + ++ A++PC +C EC F+ L H ++ H
Sbjct: 639 EKPYK-CEECGKAFKWSSKLTVHKVIHTAEKPC---KCEECGKAFKHFSALRKH-KIIHT 693
Query: 1145 DLTPETSGPRKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEGIN------- 1197
KK Y+C +C F N ++ H H E+
Sbjct: 694 G-------------------KKPYKCEECGKAFNNSSTLRKHEIIHTGEKSYKCEECALR 734
Query: 1198 -----------HECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQ 1246
++C+ C + F++ + L H I ++ + +KC C F Q++ L +
Sbjct: 735 KHEIIHTGKKPYKCEECGKAFNNSSTLRKHKIIYTGKK---PYKCEECGKAFKQSSHLTR 791
Query: 1247 HIFAVHGQEDKIYDCSQCPQKFFFQTELQNHTM 1279
H AVH E K Y C +C + F + L+ H +
Sbjct: 792 HK-AVHTGE-KPYKCGECGKAFNNSSTLKKHKL 822
Score = 123 bits (309), Expect = 1e-27
Identities = 147/636 (23%), Positives = 229/636 (36%), Gaps = 102/636 (16%)
Query: 654 HLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLD 713
H L LRK C E +E+ + T + C K F + ++ +
Sbjct: 129 HKNLRLRKD-CESVNEGKMHEEAYNKLNQCWTTTQGKIFQCNKYVKVFHKYSNSNRYKII 187
Query: 714 MHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSH 773
Y C C + F + H A+ H+ EK Y+C C F + L+ KH
Sbjct: 188 HTGKKPYKCEECGKAFKQSSHLTRHKAI-HTGEKP-YKCEECGKAFNHFSALR---KHQI 242
Query: 774 LGNPAKAHKCIFCGETFSTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHC 831
+ K +KC CG+ FS L+ H I T K Y + C KAF + L KH
Sbjct: 243 IHTGKKPYKCEECGKAFSQSSTLRKHEIIHTEEKPYKYEECGKAFSNLSALRKH------ 296
Query: 832 VFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDIC 891
G P ++ G K H+ + +E C+ C
Sbjct: 297 -------EIIHTGQKPYKCEEC------GKAFKWSSKLTVHKV----IHTAEKPCKCEEC 339
Query: 892 GAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQT 951
G A+ L+ H++ I G K +KC CS+ F + + LR+H
Sbjct: 340 GKAFKRFSALRKHKI----IHTG------------KQPYKCEECSKAFSNFSALRKHEII 383
Query: 952 HRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHP 1011
H G K Y C CG+ F LT HKV H + C C + +H +H
Sbjct: 384 HTGE-KPYKCEECGKAFKWSSKLTVHKVIHMEEKPC-KCEECGKAFKHFSALRKHKIIHT 441
Query: 1012 DLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLK 1071
+ ++C C + ++ L H H K K YKC C K
Sbjct: 442 GKKP----YKCEECGKAFNNSSTLMKHKIIHTGK----------------KPYKCEECGK 481
Query: 1072 EFRSKQDLVK---LDVNGLPYGLCAGCMARSANGQVGGLAPPEPADRPCAGLRCPECSVK 1128
F+ L + + PY C C A L + +C EC
Sbjct: 482 AFKQSSHLTRHKAIHTGEKPYK-CEEC--GKAFNHFSALRKHQIIHTGKKPYKCEECGKA 538
Query: 1129 FESAEDLESHMQVDHRDLTPETSGPRKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVA 1188
F + L H ++ H +K Y+C +C F+ + H
Sbjct: 539 FSQSSTLRKH-EIIHTG-------------------EKPYKCEECGKAFKWSSHLTRHKV 578
Query: 1189 NHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHI 1248
H E+ ++C+ C + F+ + L H I H+ + +KC C F Q++ L++H
Sbjct: 579 IHTEEKP--YKCEECGKAFNHFSALRKHKIIHTGKK---PYKCEECGKAFSQSSTLRKHE 633
Query: 1249 FAVHGQEDKIYDCSQCPQKFFFQTELQNHTMSQHAQ 1284
G+ K Y C +C + F + ++L H + A+
Sbjct: 634 IIHTGE--KPYKCEECGKAFKWSSKLTVHKVIHTAE 667
Score = 92.4 bits (228), Expect = 2e-18
Identities = 62/244 (25%), Positives = 92/244 (37%), Gaps = 41/244 (16%)
Query: 64 ESIYTCDHCQQDFESLADLTDHR-------AHRCPGDGDDDPQLSWVASSPSSKDVASPT 116
E Y C C + F + + L H+ +++C G S + P
Sbjct: 799 EKPYKCGECGKAFNNSSTLKKHKLIHTREKSYKCEECGKAFSNFSALRKHKIIHTGEKPY 858
Query: 117 QMIGDGCDLGLGEEEGGTGL----------PYPCQFCDKSFIRLSYLKRHEQIHSDKLPF 166
+ + C+ G T + PY C+ C K F S L +H+ IH+ + P+
Sbjct: 859 KC--EECECGKAFNNSSTLMKHKIIHTGEKPYKCEECGKGFNNFSTLMKHKIIHTGEKPY 916
Query: 167 KCTYCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTV 226
KC C + FK +H +HTG+K Y C E AFS L H H+ KP+KC
Sbjct: 917 KCEECGKAFKQSSHLTKHKSIHTGEKPYKCEERGKAFSHFSRLTKHRIIHTGKKPYKCEE 976
Query: 227 ---------CKRGFSSTSSLQSHMQAHKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEE 277
C + F+ +S L H H K + C+ C F+
Sbjct: 977 CEKPYKCEECGKAFNQSSHLTQHKTIHTGGK-------------TYKCEECGKAFNHLSA 1023
Query: 278 LEKH 281
L KH
Sbjct: 1024 LTKH 1027
Score = 89.4 bits (220), Expect = 2e-17
Identities = 42/121 (34%), Positives = 62/121 (51%), Gaps = 9/121 (7%)
Query: 137 PYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTG------ 190
PY C+ C K+F + S+L +H+ IH+ + P+KC + F H +H +HTG
Sbjct: 915 PYKCEECGKAFKQSSHLTKHKSIHTGEKPYKCEERGKAFSHFSRLTKHRIIHTGKKPYKC 974
Query: 191 ---DKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKN 247
+K Y C EC AF++S HL H H+ K +KC C + F+ S+L H H
Sbjct: 975 EECEKPYKCEECGKAFNQSSHLTQHKTIHTGGKTYKCEECGKAFNHLSALTKHKIIHTGE 1034
Query: 248 K 248
K
Sbjct: 1035 K 1035
Score = 65.5 bits (158), Expect = 3e-10
Identities = 46/174 (26%), Positives = 67/174 (38%), Gaps = 38/174 (21%)
Query: 64 ESIYTCDHCQQDFESLADLTDHRA-------HRCPGDGDDDPQLSWVASSPSSKDVASPT 116
E Y C+ C + F + + L H+ ++C G Q S + S
Sbjct: 885 EKPYKCEECGKGFNNFSTLMKHKIIHTGEKPYKCEECGKAFKQSSHLTKHKS-------- 936
Query: 117 QMIGDGCDLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFK 176
+ GE+ PY C+ K+F S L +H IH+ K P+KC C + +K
Sbjct: 937 --------IHTGEK------PYKCEERGKAFSHFSRLTKHRIIHTGKKPYKCEECEKPYK 982
Query: 177 ---------HKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKP 221
+H +HTG K Y C EC AF+ L H H+ KP
Sbjct: 983 CEECGKAFNQSSHLTQHKTIHTGGKTYKCEECGKAFNHLSALTKHKIIHTGEKP 1036
>gi|119120877 zinc finger protein 721 [Homo sapiens]
Length = 923
Score = 216 bits (549), Expect = 1e-55
Identities = 230/968 (23%), Positives = 347/968 (35%), Gaps = 188/968 (19%)
Query: 55 NEDDEDMEDESIYTCDHCQQDFESLADLTDHRA-------HRCPGDGDDDPQLSWVASSP 107
N+D E + C+ C + F+ +DLT H+ + C G D W
Sbjct: 97 NKDKTRHTGEKHFKCNECGKSFQKFSDLTQHKGIHAGEKPYTCEERGKD---FGWYTDLN 153
Query: 108 SSKDVASPTQMIGDGCDLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFK 167
K + + GE+ PY C+ C K+F R + L H++IH+ + +
Sbjct: 154 QHKKIHT-------------GEK------PYKCEECGKAFNRSTNLTAHKRIHNREKAYT 194
Query: 168 CTYCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVC 227
R F + + + K+HTGDK Y C EC AF S HL H K H+ KP+KC C
Sbjct: 195 GEDRDRAFGWSTNLNEYKKIHTGDKPYKCKECGKAFMHSSHLNKHEKIHTGEKPYKCKEC 254
Query: 228 KRGFSSTSSLQSHMQAHKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHP 287
+ SS+SS H + H K F C C F+ + L KH R
Sbjct: 255 GKVISSSSSFAKHKRIHTGEKP-------------FKCLECGKAFNISTTLTKH---RRI 298
Query: 288 QLSEKADLQCIHCPEVFVDENTLLAHIHQAHANQK-HKCPMCPEQFSSVEGVYCHLDSHR 346
EK C C + F L H + H +K + C C + F +Y H H
Sbjct: 299 HTGEKP-YTCEVCGKAFRQSANLYVH-RRIHTGEKPYTCGECGKTFRQSANLYVHRRIH- 355
Query: 347 QPDSSNHSVSPDPVLGSVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTK 406
D + R + + K G+K
Sbjct: 356 -----------------TGEKPYKCEDCGKAFGRYTALNQHKKIHTGEKP---------- 388
Query: 407 VVYSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHK- 465
Y C C K FNS L H + +KP +TC+ + NLNE+ +K+H
Sbjct: 389 --YKCEECGKA-FNSSTNLTAHKRIHTREKP---YTCEDRGRAFGLSTNLNEY-KKIHTG 441
Query: 466 NHAYPVMQFGN--ISAFH---------------CNYCPEMFADINSLQEHIRVSHCGPNA 508
+ Y + G I + H C C ++ +S +H R+
Sbjct: 442 DKPYKCKECGKAFIHSLHLNKHEKIHTGKKPYKCKQCGKVITSSSSFAKHKRIH------ 495
Query: 509 NPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVYSCPYC 568
G F C +C F + ++LT+H ++ H E P Y+C C
Sbjct: 496 ---TGEKPFECLECGKAFTSSTTLTKH-RRIHTG------EKP-----------YTCEVC 534
Query: 569 TNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSIS 628
+ +IL + + I K K+ + + + + + ++
Sbjct: 535 GKAFRQSAILYVHRRIHTGEKPYTCEECGKTFRQSANLYVHRRIHTGEKP---------- 584
Query: 629 NGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTT 688
Y C +C F + H K+H L K C +C +DF L Q ++ T
Sbjct: 585 ---YKCEECGKAFGRYTDLNQHKKIHTGEKLYK--CEECGKDFVWYTDLNQQKKIY--TG 637
Query: 689 STHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKK 748
Y CE C K F+ DL +H + Y C C + F +++ H + H+ EK
Sbjct: 638 EKPYKCEECGKAFAPSTDLNQHTKILTGEQSYKCEECGKAFGWSIALNQHKKI-HTGEKP 696
Query: 749 MYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETF--STEVELQCHITTHSKK 806
Y+C C F + +L H + K +KC G +F ST + I T K
Sbjct: 697 -YKCEECGKAFSRSRNL---TTHRRVHTREKPYKCEDRGRSFGWSTNLNEYKKIHTGDKL 752
Query: 807 YNCKFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNP 866
Y CK C K F L +H + G P K+ G ++ +
Sbjct: 753 YKCKECGKVFKQSSHLNRHEK-------------IHTGKKPYKCKEC------GKVITS- 792
Query: 867 EAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRP--GEDDGSRKKAE 924
+S A + E + C CG A+T L HR +P E+ G +
Sbjct: 793 ---SSSFAKHKRIHTGEKPFKCLECGKAFTSSTTLTKHRRIHTGEKPYTCEECGKAFRQS 849
Query: 925 FIKGSHK----------CNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTL 974
I H+ C C +TF L H + H G K Y C CG+ F L
Sbjct: 850 AILYVHRRIHTGEKPYTCGECGKTFRQSANLYAHKKIHTG-EKPYTCGDCGKTFRQSANL 908
Query: 975 TEHKVTHS 982
HK H+
Sbjct: 909 YAHKKIHT 916
Score = 154 bits (388), Expect = 7e-37
Identities = 196/831 (23%), Positives = 296/831 (35%), Gaps = 164/831 (19%)
Query: 513 GNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVYSCPYCTNSP 572
G F CN+C F S LT+H G E P Y+C
Sbjct: 105 GEKHFKCNECGKSFQKFSDLTQH-------KGIHAGEKP-----------YTCE--ERGK 144
Query: 573 IFGSILKLTKHIKENHKNIPL----------------AHSKKSKAEQSPVSSDVEVSSPK 616
FG L +H K + P AH + E++ D + +
Sbjct: 145 DFGWYTDLNQHKKIHTGEKPYKCEECGKAFNRSTNLTAHKRIHNREKAYTGEDRDRAFGW 204
Query: 617 RQRLSASANSISNGE--YPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQ 674
L+ I G+ Y C +C F + H K+H + C +C + S
Sbjct: 205 STNLN-EYKKIHTGDKPYKCKECGKAFMHSSHLNKHEKIHTGE--KPYKCKECGKVISSS 261
Query: 675 ESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVS 734
S +H +H T + C C K F+ L KH Y C +C + F +
Sbjct: 262 SSFAKHKRIH--TGEKPFKCLECGKAFNISTTLTKHRRIHTGEKPYTCEVCGKAFRQSAN 319
Query: 735 IQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEV 794
+ VH + H+ EK Y C C FR+ A+L VH + H G K +KC CG+ F
Sbjct: 320 LYVHRRI-HTGEKP-YTCGECGKTFRQSANLYVH-RRIHTGE--KPYKCEDCGKAFGRYT 374
Query: 795 ELQCH--ITTHSKKYNCKFCSKAFHAIILLEKH----LREKHCVFDAATENGTANGVPPM 848
L H I T K Y C+ C KAF++ L H REK + + G A G+
Sbjct: 375 ALNQHKKIHTGEKPYKCEECGKAFNSSTNLTAHKRIHTREKPYTCE---DRGRAFGL--- 428
Query: 849 ATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRD 908
+ N +E + + + Y C CG A+ + L H
Sbjct: 429 -------------------STNLNEYKK--IHTGDKPYKCKECGKAFIHSLHLNKH---- 463
Query: 909 HNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERF 968
+K K +KC C + S + +H + H G K + C CG+ F
Sbjct: 464 ------------EKIHTGKKPYKCKQCGKVITSSSSFAKHKRIHTGE-KPFECLECGKAF 510
Query: 969 PSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQT 1028
S TLT+H+ H+ TC +C + H ++H + + C C +T
Sbjct: 511 TSSTTLTKHRRIHTGEKPY-TCEVCGKAFRQSAILYVHRRIHTGEKP----YTCEECGKT 565
Query: 1029 VTSTLELKIHGTFHM-QKLAGSSAASSPNGQGL-----------QKLYKCALCLKEFRSK 1076
+ L +H H +K G+ +KLYKC C K+F
Sbjct: 566 FRQSANLYVHRRIHTGEKPYKCEECGKAFGRYTDLNQHKKIHTGEKLYKCEECGKDFVWY 625
Query: 1077 QDL---VKLDVNGLPYGL--CAGCMARSAN-------------------GQVGGLAPP-- 1110
DL K+ PY C A S + G+ G +
Sbjct: 626 TDLNQQKKIYTGEKPYKCEECGKAFAPSTDLNQHTKILTGEQSYKCEECGKAFGWSIALN 685
Query: 1111 -----EPADRPCAGLRCPECSVKFESAEDLESHMQVDHRD--LTPETSGPRKGTQTSPVP 1163
++P +C EC F + +L +H +V R+ E G G T+
Sbjct: 686 QHKKIHTGEKP---YKCEECGKAFSRSRNLTTHRRVHTREKPYKCEDRGRSFGWSTNLNE 742
Query: 1164 RKKT------YQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHL 1217
KK Y+C +C F+ + H H ++ ++CK C ++ S + H
Sbjct: 743 YKKIHTGDKLYKCKECGKVFKQSSHLNRHEKIHTGKKP--YKCKECGKVITSSSSFAKHK 800
Query: 1218 IEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKF 1268
H+ E FKC C F + L +H +H E K Y C +C + F
Sbjct: 801 RIHTGE---KPFKCLECGKAFTSSTTLTKH-RRIHTGE-KPYTCEECGKAF 846
Score = 132 bits (331), Expect = 3e-30
Identities = 156/659 (23%), Positives = 224/659 (33%), Gaps = 119/659 (18%)
Query: 632 YPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTH 691
+ CN+C F F H +H + C + +DF L QH +H T
Sbjct: 109 FKCNECGKSFQKFSDLTQHKGIHAGE--KPYTCEERGKDFGWYTDLNQHKKIH--TGEKP 164
Query: 692 YVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYR 751
Y CE C K F+ +L H + Y F ++ + + H+ +K Y+
Sbjct: 165 YKCEECGKAFNRSTNLTAHKRIHNREKAYTGEDRDRAFGWSTNLNEYKKI-HTGDKP-YK 222
Query: 752 CTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCH--ITTHSKKYNC 809
C C F + L H K H G K +KC CG+ S+ H I T K + C
Sbjct: 223 CKECGKAFMHSSHLNKHEK-IHTGE--KPYKCKECGKVISSSSSFAKHKRIHTGEKPFKC 279
Query: 810 KFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAP 869
C KAF+ L KH R +K ++ G +
Sbjct: 280 LECGKAFNISTTLTKHRRIH-------------------TGEKPYTCEVCGKAFRQSANL 320
Query: 870 NSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGS 929
H + E Y C CG + L HR I GE
Sbjct: 321 YVHRR----IHTGEKPYTCGECGKTFRQSANLYVHR----RIHTGEKP------------ 360
Query: 930 HKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGT 989
+KC C + F L +H + H G K Y C CG+ F S LT HK H++ T
Sbjct: 361 YKCEDCGKAFGRYTALNQHKKIHTGE-KPYKCEECGKAFNSSTNLTAHKRIHTRE-KPYT 418
Query: 990 CRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGS 1049
C E+ ++H + ++C C + +L L H H K
Sbjct: 419 CEDRGRAFGLSTNLNEYKKIHTGDK----PYKCKECGKAFIHSLHLNKHEKIHTGK---- 470
Query: 1050 SAASSPNGQGLQKLYKCALCLKEFRSKQDLVKLDVNGLPYGLCAGCMARSANGQVGGLAP 1109
K YKC C K S K R G
Sbjct: 471 ------------KPYKCKQCGKVITSSSSFAK--------------HKRIHTG------- 497
Query: 1110 PEPADRPCAGLRCPECSVKFESAEDLESHMQV--DHRDLTPETSGPRKGTQTSPV----- 1162
++P C EC F S+ L H ++ + T E G K + S +
Sbjct: 498 ----EKP---FECLECGKAFTSSTTLTKHRRIHTGEKPYTCEVCG--KAFRQSAILYVHR 548
Query: 1163 ---PRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIE 1219
+K Y C +C TF + +H H E+ ++C+ C + F L H
Sbjct: 549 RIHTGEKPYTCEECGKTFRQSANLYVHRRIHTGEK--PYKCEECGKAFGRYTDLNQHKKI 606
Query: 1220 HSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNHT 1278
H+ E + +KC C FV L Q G +K Y C +C + F T+L HT
Sbjct: 607 HTGEKL---YKCEECGKDFVWYTDLNQQKKIYTG--EKPYKCEECGKAFAPSTDLNQHT 660
Score = 131 bits (329), Expect = 5e-30
Identities = 198/912 (21%), Positives = 301/912 (33%), Gaps = 203/912 (22%)
Query: 409 YSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHA 468
+ C C K F + L H K IHA ++ +TC+ +LN+H +K+H
Sbjct: 109 FKCNECGK-SFQKFSDLTQH-KGIHAG--EKPYTCEERGKDFGWYTDLNQH-KKIHTGE- 162
Query: 469 YPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSH-------------CGPNANPSD--- 512
+ C C + F +L H R+ + G + N ++
Sbjct: 163 ---------KPYKCEECGKAFNRSTNLTAHKRIHNREKAYTGEDRDRAFGWSTNLNEYKK 213
Query: 513 ---GNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVYSCPYCT 569
G+ + C +C F+ S L +H ++ H E P Y C C
Sbjct: 214 IHTGDKPYKCKECGKAFMHSSHLNKH-EKIHTG------EKP-----------YKCKEC- 254
Query: 570 NSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSISN 629
+ S KH K H K K + + ++ + K +R+
Sbjct: 255 -GKVISSSSSFAKH-KRIHTG-----EKPFKCLECGKAFNISTTLTKHRRIHTGEKP--- 304
Query: 630 GEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTS 689
Y C C F + H ++H + C +C + F +L H +H T
Sbjct: 305 --YTCEVCGKAFRQSANLYVHRRIHTGE--KPYTCGECGKTFRQSANLYVHRRIH--TGE 358
Query: 690 THYVCESCDKQFSSVDDLQKHLLDMHTFVL-YHCTLCQEVFDSKVSIQVHLAVKHSNEKK 748
Y CE C K F L +H +HT Y C C + F+S ++ H + H+ EK
Sbjct: 359 KPYKCEDCGKAFGRYTALNQHK-KIHTGEKPYKCEECGKAFNSSTNLTAHKRI-HTREKP 416
Query: 749 MYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCH--ITTHSKK 806
Y C F +L + K H G+ K +KC CG+ F + L H I T K
Sbjct: 417 -YTCEDRGRAFGLSTNLNEY-KKIHTGD--KPYKCKECGKAFIHSLHLNKHEKIHTGKKP 472
Query: 807 YNCKFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNP 866
Y CK C K + KH R G P + A L
Sbjct: 473 YKCKQCGKVITSSSSFAKHKR-------------IHTGEKPFECLECGKAFTSSTTLTKH 519
Query: 867 EAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFI 926
+ E Y C++CG A+ +L HR I GE
Sbjct: 520 RR----------IHTGEKPYTCEVCGKAFRQSAILYVHR----RIHTGEKP--------- 556
Query: 927 KGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHS---- 982
+ C C +TF L H + H G K Y C CG+ F L +HK H+
Sbjct: 557 ---YTCEECGKTFRQSANLYVHRRIHTGE-KPYKCEECGKAFGRYTDLNQHKKIHTGEKL 612
Query: 983 -------------------KSLDTGT----CRICKMPLQSEEEFIEHCQM---------- 1009
K + TG C C + +H ++
Sbjct: 613 YKCEECGKDFVWYTDLNQQKKIYTGEKPYKCEECGKAFAPSTDLNQHTKILTGEQSYKCE 672
Query: 1010 --------------HPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLA------GS 1049
H + ++C C + + + L H H ++ G
Sbjct: 673 ECGKAFGWSIALNQHKKIHTGEKPYKCEECGKAFSRSRNLTTHRRVHTREKPYKCEDRGR 732
Query: 1050 SAASSPNGQGLQK------LYKCALCLKEFRSKQDL---VKLDVNGLPYGLCAGC-MARS 1099
S S N +K LYKC C K F+ L K+ PY C C +
Sbjct: 733 SFGWSTNLNEYKKIHTGDKLYKCKECGKVFKQSSHLNRHEKIHTGKKPYK-CKECGKVIT 791
Query: 1100 ANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVD--HRDLTPETSGPRKGT 1157
++ ++P +C EC F S+ L H ++ + T E G K
Sbjct: 792 SSSSFAKHKRIHTGEKP---FKCLECGKAFTSSTTLTKHRRIHTGEKPYTCEECG--KAF 846
Query: 1158 QTSPV--------PRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDS 1209
+ S + +K Y C +C TF + H H E+ + C C + F
Sbjct: 847 RQSAILYVHRRIHTGEKPYTCGECGKTFRQSANLYAHKKIHTGEK--PYTCGDCGKTFRQ 904
Query: 1210 PAKLLCHLIEHS 1221
A L H H+
Sbjct: 905 SANLYAHKKIHT 916
Score = 87.8 bits (216), Expect = 6e-17
Identities = 37/112 (33%), Positives = 61/112 (54%)
Query: 137 PYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 196
P+ C C K+F + L +H +IH+ + P+ C C + F+ H ++HTG+K Y C
Sbjct: 808 PFKCLECGKAFTSSTTLTKHRRIHTGEKPYTCEECGKAFRQSAILYVHRRIHTGEKPYTC 867
Query: 197 HECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNK 248
EC F +S +L H K H+ KP+ C C + F +++L +H + H +K
Sbjct: 868 GECGKTFRQSANLYAHKKIHTGEKPYTCGDCGKTFRQSANLYAHKKIHTGDK 919
Score = 65.9 bits (159), Expect = 2e-10
Identities = 82/368 (22%), Positives = 122/368 (33%), Gaps = 63/368 (17%)
Query: 931 KCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTC 990
+CN + F + H G KH+ C CG+ F LT+HK H+
Sbjct: 82 QCNARVKVFSKFANSNKDKTRHTGE-KHFKCNECGKSFQKFSDLTQHKGIHAG------- 133
Query: 991 RICKMPLQSEEE-----FIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQK 1045
+ P EE + H + ++C C + + L H H ++
Sbjct: 134 ---EKPYTCEERGKDFGWYTDLNQHKKIHTGEKPYKCEECGKAFNRSTNLTAHKRIHNRE 190
Query: 1046 LA------GSSAASSPNGQGLQKL------YKCALCLKEFRSKQDL---VKLDVNGLPYG 1090
A + S N +K+ YKC C K F L K+ PY
Sbjct: 191 KAYTGEDRDRAFGWSTNLNEYKKIHTGDKPYKCKECGKAFMHSSHLNKHEKIHTGEKPY- 249
Query: 1091 LCAGC-MARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPE 1149
C C S++ ++P +C EC F + L H ++
Sbjct: 250 KCKECGKVISSSSSFAKHKRIHTGEKP---FKCLECGKAFNISTTLTKHRRIH------- 299
Query: 1150 TSGPRKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDS 1209
+K Y C C F + +H H E+ + C C + F
Sbjct: 300 -------------TGEKPYTCEVCGKAFRQSANLYVHRRIHTGEK--PYTCGECGKTFRQ 344
Query: 1210 PAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFF 1269
A L H H+ E +KC C F + L QH +H E K Y C +C + F
Sbjct: 345 SANLYVHRRIHTGE---KPYKCEDCGKAFGRYTALNQH-KKIHTGE-KPYKCEECGKAFN 399
Query: 1270 FQTELQNH 1277
T L H
Sbjct: 400 SSTNLTAH 407
>gi|154800445 zinc finger protein 62 homolog [Homo sapiens]
Length = 840
Score = 210 bits (535), Expect = 6e-54
Identities = 205/847 (24%), Positives = 314/847 (37%), Gaps = 154/847 (18%)
Query: 138 YPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCH 197
Y C C +F S L+ H++IH+ + P+KC C + + S H H+G+K C
Sbjct: 109 YECDDCGGTFRSSSSLRVHKRIHTGEKPYKCEECGKAYMSYSSLINHKSTHSGEKNCKCD 168
Query: 198 ECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEKE 257
EC +F+ S L H + H+ KP++C C + F ++S L+ H + H K
Sbjct: 169 ECGKSFNYSSVLDQHKRIHTGEKPYECGECGKAFRNSSGLRVHKRIHTGEKP-------- 220
Query: 258 AKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQA 317
+ CD C TFS + L H + EK +C C + F+ TLL H
Sbjct: 221 -----YECDICGKTFSNSSGLRVH---KRIHTGEKP-YECDECGKAFITCRTLLNHKSIH 271
Query: 318 HANQKHKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDSSAS 377
++ +KC C + F+ + H H D
Sbjct: 272 FGDKPYKCDECEKSFNYSSLLIQHKVIH-------------------TGEKPYECDECGK 312
Query: 378 VERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHADKP 437
R S+ K + +K Y C C K F+ + L +H K+IH K
Sbjct: 313 AFRNSSGLIVHKRIHTGEKP-----------YKCDVCGKA-FSYSSGLAVH-KSIHPGK- 358
Query: 438 QQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINSLQE 497
++H C+ C S L +H R +H + C+ C + F + L+
Sbjct: 359 -KAHECKECGKSFSYNSLLLQH-RTIHTGER----------PYVCDVCGKTFRNNAGLKV 406
Query: 498 HIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPTQ 557
H R+ G + C+ C +++ SSL H G E P
Sbjct: 407 HRRLH---------TGEKPYKCDVCGKAYISRSSLKNH-------KGIHLGEKP------ 444
Query: 558 SFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKR 617
Y C YC S + S L+ K I K K+ S + + + +R
Sbjct: 445 -----YKCSYCEKSFNYSSALEQHKRIHTREKPFGCDECGKAFRNNSGLKVHKRIHTGER 499
Query: 618 QRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESL 677
Y C +C + + S H +H K C +C++ F + +L
Sbjct: 500 P-------------YKCEECGKAYISLSSLINHKSVHPGEKPFK--CDECEKAFITYRTL 544
Query: 678 LQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQV 737
H VH Y C+ C+K F+ L +H Y C C++VF + S++V
Sbjct: 545 TNHKKVHL--GEKPYKCDVCEKSFNYTSLLSQHRRVHTREKPYECDRCEKVFRNNSSLKV 602
Query: 738 HLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQ 797
H + H+ E+ Y C C + + L H K +H G H C CG+ F + L
Sbjct: 603 HKRI-HTGERP-YECDVCGKAYISHSSLINH-KSTHPGKTP--HTCDECGKAFFSSRTLI 657
Query: 798 CHITTH--SKKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEP 855
H H K + C C K+F LL +H R +K
Sbjct: 658 SHKRVHLGEKPFKCVECGKSFSYSSLLSQHKRIH-------------------TGEKPYV 698
Query: 856 ADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGE 915
D G +N H+ + E Y CD CG AY L NH+ ++ G
Sbjct: 699 CDRCGKAFRNSSGLTVHKR----IHTGEKPYECDECGKAYISHSSLINHK----SVHQG- 749
Query: 916 DDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLT 975
K + C C ++F + L +H + H G K Y C CG+ F LT
Sbjct: 750 -----------KQPYNCE-CGKSFNYRSVLDQHKRIHTGK-KPYRCNECGKAFNIRSNLT 796
Query: 976 EHKVTHS 982
+HK TH+
Sbjct: 797 KHKRTHT 803
Score = 206 bits (525), Expect = 9e-53
Identities = 194/790 (24%), Positives = 309/790 (39%), Gaps = 121/790 (15%)
Query: 64 ESIYTCDHCQQDFESLADLTDHRAHRCPGDGDDDPQLSWVASSPSSKDVASPTQMIGDGC 123
+ ++ CD C + F+ + L H+ + S SS V
Sbjct: 78 KKLHKCDECGKSFKYNSRLVQHKIMHTGEKRYECDDCGGTFRSSSSLRVHKR-------- 129
Query: 124 DLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDR 183
+ GE+ PY C+ C K+++ S L H+ HS + KC C + F + D+
Sbjct: 130 -IHTGEK------PYKCEECGKAYMSYSSLINHKSTHSGEKNCKCDECGKSFNYSSVLDQ 182
Query: 184 HIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQA 243
H ++HTG+K Y C EC AF S L++H + H+ KP++C +C + FS++S L+ H +
Sbjct: 183 HKRIHTGEKPYECGECGKAFRNSSGLRVHKRIHTGEKPYECDICGKTFSNSSGLRVHKRI 242
Query: 244 HKKNKEH---------------LAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQ 288
H K + L + CD CE +F+ + L +H +
Sbjct: 243 HTGEKPYECDECGKAFITCRTLLNHKSIHFGDKPYKCDECEKSFNYSSLLIQHKVIH--- 299
Query: 289 LSEKADLQCIHCPEVFVDENTLLAHIHQAHANQKHKCPMCPEQFSSVEGVYCHLDSHRQP 348
+ + +C C + F + + L+ H + +KC +C + FS G+ H H P
Sbjct: 300 -TGEKPYECDECGKAFRNSSGLIVHKRIHTGEKPYKCDVCGKAFSYSSGLAVHKSIH--P 356
Query: 349 DSSNHSVSPDPVLGSVASMSSATPDSSASVERGSTP------DSTLKPLRGQKKMRDDGQ 402
H G S +S ++ G P T + G K R
Sbjct: 357 GKKAHECKE---CGKSFSYNSLLL-QHRTIHTGERPYVCDVCGKTFRNNAGLKVHRRLHT 412
Query: 403 GWTKVVYSCPYCSKRDFNSLAVLEIHLKTIH-ADKPQQSHTCQICLDSMPTLYNLNEHVR 461
G + Y C C K + S + L+ H K IH +KP + C C S L +H +
Sbjct: 413 G--EKPYKCDVCGKA-YISRSSLKNH-KGIHLGEKP---YKCSYCEKSFNYSSALEQH-K 464
Query: 462 KLHKNHAYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQ 521
++H F C+ C + F + + L+ H R+ G + C +
Sbjct: 465 RIHTRE----------KPFGCDECGKAFRNNSGLKVHKRI---------HTGERPYKCEE 505
Query: 522 CSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLT 581
C +++ SSL H K P +P + C C + I T
Sbjct: 506 CGKAYISLSSLINH-----------KSVHPGEKP-------FKCDECEKAFI-------T 540
Query: 582 KHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSISNGE--YPCNQCDL 639
NHK + L + P DV S L + + E Y C++C+
Sbjct: 541 YRTLTNHKKVHLG--------EKPYKCDVCEKSFNYTSLLSQHRRVHTREKPYECDRCEK 592
Query: 640 KFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDK 699
F N S + H ++H R C C + + S SL+ H + H T + C+ C K
Sbjct: 593 VFRNNSSLKVHKRIHTG--ERPYECDVCGKAYISHSSLINHKSTH--PGKTPHTCDECGK 648
Query: 700 QFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDF 759
F S L H + C C + F + H + H+ EK Y C C F
Sbjct: 649 AFFSSRTLISHKRVHLGEKPFKCVECGKSFSYSSLLSQHKRI-HTGEKP-YVCDRCGKAF 706
Query: 760 RKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHITTHSKK--YNCKFCSKAFH 817
R + L VH K H G K ++C CG+ + + L H + H K YNC+ C K+F+
Sbjct: 707 RNSSGLTVH-KRIHTGE--KPYECDECGKAYISHSSLINHKSVHQGKQPYNCE-CGKSFN 762
Query: 818 AIILLEKHLR 827
+L++H R
Sbjct: 763 YRSVLDQHKR 772
Score = 170 bits (431), Expect = 7e-42
Identities = 207/856 (24%), Positives = 309/856 (36%), Gaps = 150/856 (17%)
Query: 449 SMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNA 508
S P+L V+KLHK C+ C + F + L +H ++ H G
Sbjct: 66 SYPSLQQKTNAVKKLHK----------------CDECGKSFKYNSRLVQH-KIMHTG--- 105
Query: 509 NPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVYSCPYC 568
+ C+ C F + SSL H ++ H E P Y C C
Sbjct: 106 -----EKRYECDDCGGTFRSSSSLRVH-KRIHTG------EKP-----------YKCEEC 142
Query: 569 TNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSIS 628
+ + S L NHK+ HS + + SS Q I
Sbjct: 143 GKAYMSYSSLI-------NHKS---THSGEKNCKCDECGKSFNYSSVLDQH-----KRIH 187
Query: 629 NGE--YPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYM 686
GE Y C +C F N + H ++H + C C + F + L H +H
Sbjct: 188 TGEKPYECGECGKAFRNSSGLRVHKRIHTGE--KPYECDICGKTFSNSSGLRVHKRIH-- 243
Query: 687 TTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNE 746
T Y C+ C K F + L H Y C C++ F+ S+ + V H+ E
Sbjct: 244 TGEKPYECDECGKAFITCRTLLNHKSIHFGDKPYKCDECEKSFNYS-SLLIQHKVIHTGE 302
Query: 747 KKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHITTH--S 804
K Y C C FR + L VH K H G K +KC CG+ FS L H + H
Sbjct: 303 KP-YECDECGKAFRNSSGLIVH-KRIHTGE--KPYKCDVCGKAFSYSSGLAVHKSIHPGK 358
Query: 805 KKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLK 864
K + CK C K+F LL +H R H G P D+ G +
Sbjct: 359 KAHECKECGKSFSYNSLLLQH-RTIH------------TGERPYV------CDVCGKTFR 399
Query: 865 NPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAE 924
N H + E Y CD+CG AY L+NH+ +P + K
Sbjct: 400 NNAGLKVHRR----LHTGEKPYKCDVCGKAYISRSSLKNHKGIHLGEKPYKCSYCEKSFN 455
Query: 925 FIKG--SHK----------CNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLL 972
+ HK C+ C + F + +GL+ H + H G + Y C CG+ + SL
Sbjct: 456 YSSALEQHKRIHTREKPFGCDECGKAFRNNSGLKVHKRIHTGE-RPYKCEECGKAYISLS 514
Query: 973 TLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTST 1032
+L HK H C C+ + H ++H + ++C VC ++ T
Sbjct: 515 SLINHKSVHPGEKPF-KCDECEKAFITYRTLTNHKKVHLGEKP----YKCDVCEKSFNYT 569
Query: 1033 LELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLV---KLDVNGLPY 1089
L H H + +K Y+C C K FR+ L ++ PY
Sbjct: 570 SLLSQHRRVHTR----------------EKPYECDRCEKVFRNNSSLKVHKRIHTGERPY 613
Query: 1090 GLCAGCMARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPE 1149
A ++ + P P C EC F S+ L SH +V + +
Sbjct: 614 ECDVCGKAYISHSSLINHKSTHPGKTPHT---CDECGKAFFSSRTLISHKRVHLGEKPFK 670
Query: 1150 TSGPRKGTQTSPV--------PRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECK 1201
K S + +K Y C +C F N + +H H E+ +EC
Sbjct: 671 CVECGKSFSYSSLLSQHKRIHTGEKPYVCDRCGKAFRNSSGLTVHKRIHTGEK--PYECD 728
Query: 1202 LCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDC 1261
C + + S + L+ H H + + C C F + L QH G+ K Y C
Sbjct: 729 ECGKAYISHSSLINHKSVHQGK---QPYNCE-CGKSFNYRSVLDQHKRIHTGK--KPYRC 782
Query: 1262 SQCPQKFFFQTELQNH 1277
++C + F ++ L H
Sbjct: 783 NECGKAFNIRSNLTKH 798
Score = 162 bits (409), Expect = 3e-39
Identities = 167/757 (22%), Positives = 269/757 (35%), Gaps = 118/757 (15%)
Query: 16 LAWDSSVTAAGGLEGEPECDQKTSRALEDRNSVTSQEERNEDDEDMEDESIYTCDHCQQD 75
+++ S + GE C + +SV Q +R E Y C C +
Sbjct: 147 MSYSSLINHKSTHSGEKNCKCDECGKSFNYSSVLDQHKRIHTGEKP-----YECGECGKA 201
Query: 76 FESLADLTDH-RAHRCPGDGDDDPQLSWVASSPSSKDVASPTQMIGDGCDLGLGEEEGGT 134
F + + L H R H P D+ T G + G
Sbjct: 202 FRNSSGLRVHKRIH--------------TGEKPYECDICGKTFSNSSGLRVHKRIHTGEK 247
Query: 135 GLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKY 194
PY C C K+FI L H+ IH P+KC C + F + +H +HTG+K Y
Sbjct: 248 --PYECDECGKAFITCRTLLNHKSIHFGDKPYKCDECEKSFNYSSLLIQHKVIHTGEKPY 305
Query: 195 HCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKS 254
C EC AF S L +H + H+ KP+KC VC + FS +S L H H K H K
Sbjct: 306 ECDECGKAFRNSSGLIVHKRIHTGEKPYKCDVCGKAFSYSSGLAVHKSIHPGKKAHECKE 365
Query: 255 ---------------EKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIH 299
+ ++CD C TF L+ H R EK +C
Sbjct: 366 CGKSFSYNSLLLQHRTIHTGERPYVCDVCGKTFRNNAGLKVH---RRLHTGEK-PYKCDV 421
Query: 300 CPEVFVDENTLLAHIHQAHANQKHKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDP 359
C + ++ ++L H + +KC C + F+ L+ H++ + D
Sbjct: 422 CGKAYISRSSLKNHKGIHLGEKPYKCSYCEKSFNYSSA----LEQHKRIHTREKPFGCDE 477
Query: 360 VLGSVASMSSA-------TPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCP 412
+ + S T + E +L L K + + + C
Sbjct: 478 CGKAFRNNSGLKVHKRIHTGERPYKCEECGKAYISLSSLINHKSVHPG-----EKPFKCD 532
Query: 413 YCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVM 472
C K F + L H K +KP + C +C S L++H R++H
Sbjct: 533 ECEKA-FITYRTLTNHKKVHLGEKP---YKCDVCEKSFNYTSLLSQH-RRVHTRE----- 582
Query: 473 QFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSL 532
+ C+ C ++F + +SL+ H R+ G + C+ C +++ SSL
Sbjct: 583 -----KPYECDRCEKVFRNNSSLKVHKRI---------HTGERPYECDVCGKAYISHSSL 628
Query: 533 TEHIQQAHCSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIP 592
H K P P ++C C + L K + K
Sbjct: 629 INH-----------KSTHPGKTP-------HTCDECGKAFFSSRTLISHKRVHLGEKPFK 670
Query: 593 LAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLK 652
KS + S +S + + ++ Y C++C F N H +
Sbjct: 671 CVECGKSFSYSSLLSQHKRIHTGEK-------------PYVCDRCGKAFRNSSGLTVHKR 717
Query: 653 LHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLL 712
+H + C +C + + S SL+ H +VH Y CE C K F+ L +H
Sbjct: 718 IHTG--EKPYECDECGKAYISHSSLINHKSVH--QGKQPYNCE-CGKSFNYRSVLDQHKR 772
Query: 713 DMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKM 749
Y C C + F+ + ++ H H+ E+ +
Sbjct: 773 IHTGKKPYRCNECGKAFNIRSNLTKHKRT-HTGEESL 808
Score = 146 bits (369), Expect = 1e-34
Identities = 211/973 (21%), Positives = 323/973 (33%), Gaps = 262/973 (26%)
Query: 253 KSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLA 312
+ + A K CD C +F L +H + + + +C C F ++L
Sbjct: 71 QQKTNAVKKLHKCDECGKSFKYNSRLVQHKIMH----TGEKRYECDDCGGTFRSSSSLRV 126
Query: 313 HIHQAHANQKHKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSATP 372
H + +KC C + + S Y L +H+ S HS
Sbjct: 127 HKRIHTGEKPYKCEECGKAYMS----YSSLINHK----STHS------------------ 160
Query: 373 DSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTI 432
G+K + C C K FN +VL+ H +
Sbjct: 161 --------------------GEKNCK------------CDECGK-SFNYSSVLDQHKRIH 187
Query: 433 HADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADI 492
+KP + C C + L H +++H + C+ C + F++
Sbjct: 188 TGEKPYE---CGECGKAFRNSSGLRVH-KRIHTGE----------KPYECDICGKTFSNS 233
Query: 493 NSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPV 552
+ L+ H R+ G + C++C F+T +L H + H + P
Sbjct: 234 SGLRVHKRIH---------TGEKPYECDECGKAFITCRTLLNH-KSIHFG------DKP- 276
Query: 553 VQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEV 612
Y C C S + S+L K I K P + KA ++ SS + V
Sbjct: 277 ----------YKCDECEKSFNYSSLLIQHKVIHTGEK--PYECDECGKAFRN--SSGLIV 322
Query: 613 SSPKRQRLSASANSISNGE--YPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKED 670
I GE Y C+ C FS H +H + C +C +
Sbjct: 323 HK-----------RIHTGEKPYKCDVCGKAFSYSSGLAVHKSIHPGK--KAHECKECGKS 369
Query: 671 FDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVL-YHCTLCQEVF 729
F LLQH T+H T YVC+ C K F + L+ H +HT Y C +C + +
Sbjct: 370 FSYNSLLLQHRTIH--TGERPYVCDVCGKTFRNNAGLKVHRR-LHTGEKPYKCDVCGKAY 426
Query: 730 DSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGET 789
S+ S++ H + H EK Y+C+ C F + L+ +H + K C CG+
Sbjct: 427 ISRSSLKNHKGI-HLGEKP-YKCSYCEKSFNYSSALE---QHKRIHTREKPFGCDECGKA 481
Query: 790 FSTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPP 847
F L+ H I T + Y C+ C KA+ ++ L H G P
Sbjct: 482 FRNNSGLKVHKRIHTGERPYKCEECGKAYISLSSLINH-------------KSVHPGEKP 528
Query: 848 MATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLR 907
+ E A + L N + V E Y CD+C ++ LL HR
Sbjct: 529 FKCDECEKAFITYRTLTNHKK----------VHLGEKPYKCDVCEKSFNYTSLLSQHRRV 578
Query: 908 DHNIRPGEDDGSRK------------KAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGP 955
+P E D K + + ++C+VC + + S + L H TH G
Sbjct: 579 HTREKPYECDRCEKVFRNNSSLKVHKRIHTGERPYECDVCGKAYISHSSLINHKSTHPGK 638
Query: 956 AKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRN 1015
H C CG+ F S TL HK H + + P
Sbjct: 639 TPH-TCDECGKAFFSSRTLISHKRVH----------LGEKP------------------- 668
Query: 1016 SLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRS 1075
F+CV C ++ + + L H H +K Y C C K FR+
Sbjct: 669 ----FKCVECGKSFSYSSLLSQHKRIHTG----------------EKPYVCDRCGKAFRN 708
Query: 1076 KQDLV---KLDVNGLPYGLCAGCMARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESA 1132
L ++ PY C EC + S
Sbjct: 709 SSGLTVHKRIHTGEKPY-------------------------------ECDECGKAYISH 737
Query: 1133 EDLESHMQVDHRDLTPETSGPRKGTQTSPV--------PRKKTYQCIKCQMTFENEREIQ 1184
L +H V H+ P K V KK Y+C +C F +
Sbjct: 738 SSLINHKSV-HQGKQPYNCECGKSFNYRSVLDQHKRIHTGKKPYRCNECGKAFNIRSNLT 796
Query: 1185 IHVANHMIEEGIN 1197
H H EE +N
Sbjct: 797 KHKRTHTGEESLN 809
Score = 92.0 bits (227), Expect = 3e-18
Identities = 105/458 (22%), Positives = 171/458 (37%), Gaps = 88/458 (19%)
Query: 859 QGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDG 918
QG ++N S+ + + +A + ++ CD CG ++ L H++ + GE
Sbjct: 55 QGKRVENING-TSYPSLQQKTNAVKKLHKCDECGKSFKYNSRLVQHKI----MHTGEK-- 107
Query: 919 SRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHK 978
++C+ C TF S + LR H + H G K Y C CG+ + S +L HK
Sbjct: 108 ----------RYECDDCGGTFRSSSSLRVHKRIHTG-EKPYKCEECGKAYMSYSSLINHK 156
Query: 979 VTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPD------------LRNSL--------- 1017
THS + C C +H ++H RNS
Sbjct: 157 STHSGEKNC-KCDECGKSFNYSSVLDQHKRIHTGEKPYECGECGKAFRNSSGLRVHKRIH 215
Query: 1018 TG---FRCVVCMQTVTSTLELKIHGTFHMQK---------LAGSSAASSPNGQGL---QK 1062
TG + C +C +T +++ L++H H + A + + N + + K
Sbjct: 216 TGEKPYECDICGKTFSNSSGLRVHKRIHTGEKPYECDECGKAFITCRTLLNHKSIHFGDK 275
Query: 1063 LYKCALCLKEFRSKQDLVK---LDVNGLPYGLCAGCMARSANGQVGGLAPPEPADRPCAG 1119
YKC C K F L++ + PY C C N GL +
Sbjct: 276 PYKCDECEKSFNYSSLLIQHKVIHTGEKPYE-CDECGKAFRNS--SGLIVHKRIHTGEKP 332
Query: 1120 LRCPECSVKFESAEDLESHMQVDHRDLTPETSGPRKGTQTSPVPRKKTYQCIKCQMTFEN 1179
+C C F + L H + P KK ++C +C +F
Sbjct: 333 YKCDVCGKAFSYSSGLAVHKSIH--------------------PGKKAHECKECGKSFSY 372
Query: 1180 EREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFV 1239
+ H H E + C +C + F + A L H H+ E +KC VC ++
Sbjct: 373 NSLLLQHRTIHTGER--PYVCDVCGKTFRNNAGLKVHRRLHTGE---KPYKCDVCGKAYI 427
Query: 1240 QANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNH 1277
+ L+ H +H E K Y CS C + F + + L+ H
Sbjct: 428 SRSSLKNH-KGIHLGE-KPYKCSYCEKSFNYSSALEQH 463
>gi|211057416 zinc finger protein 841 [Homo sapiens]
Length = 924
Score = 207 bits (527), Expect = 5e-53
Identities = 186/711 (26%), Positives = 285/711 (40%), Gaps = 119/711 (16%)
Query: 134 TGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKK 193
T PY C K+F R S L H+ +H+ P++C C R+F+ H + HTGDK
Sbjct: 285 TEKPYRCNESGKAFHRGSLLTVHQIVHTRGKPYQCDVCGRIFRQNSDLVNHRRSHTGDKP 344
Query: 194 YHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAH--------- 244
Y C+EC +FS+S HL +H + H+ KP+KC C + FS +SSL +H H
Sbjct: 345 YICNECGKSFSKSSHLAVHQRIHTGEKPYKCNRCGKCFSQSSSLATHQTVHTGDKPYKCN 404
Query: 245 ------KKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCI 298
K+N A A K + CD C F Q +L +H + + + +C
Sbjct: 405 ECGKTFKRNSSLTAHHIIHAGKKPYTCDVCGKVFYQNSQLVRHQIIH----TGETPYKCN 460
Query: 299 HCPEVFVDENTLLAHIHQAHANQK-HKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSP 357
C +VF + L H + H +K +KC C + FS + HL H++ +
Sbjct: 461 ECGKVFFQRSRLAGH-RRIHTGEKPYKCNECGKVFSQ----HSHLAVHQRVHTGEKPYKC 515
Query: 358 DPVLGSVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKR 417
+ + + GS + G+K Y C C K
Sbjct: 516 N--------------ECGKAFNWGSLLTVHQRIHTGEKP------------YKCNVCGK- 548
Query: 418 DFNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNI 477
FN L +H++ +KP + C + T Y+ +++H
Sbjct: 549 VFNYGGYLSVHMRCHTGEKPLHCNKCGMVF----TYYSCLARHQRMHTGE---------- 594
Query: 478 SAFHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQ 537
+ CN C ++F D +L H R SH G F CN+C F S L H +
Sbjct: 595 KPYKCNVCGKVFIDSGNLSIH-RRSH--------TGEKPFQCNECGKVFSYYSCLARH-R 644
Query: 538 QAHCSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSK 597
+ H E P Y C C + + LTKH+ + P ++
Sbjct: 645 KIHTG------EKP-----------YKCNDCGKA--YTQRSSLTKHLVIHTGENPYHCNE 685
Query: 598 KSKAEQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLEL 657
+A + S K R N + C++C FS+ S H + H
Sbjct: 686 FGEA---------FIQSSKLARY--HRNPTGEKPHKCSECGRTFSHKTSLVYHQRRHTGE 734
Query: 658 LLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTF 717
+ K C +C + F+S +L +H +H T Y C C K F L +H +HT
Sbjct: 735 MPYK--CIECGKVFNSTTTLARHRRIH--TGEKPYKCNECGKVFRYRSGLARH-WSIHTG 789
Query: 718 VL-YHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGN 776
Y C C + F + SI ++ + H+ EK Y+C C F + ++L H + +H G
Sbjct: 790 EKPYKCNECGKAFRVR-SILLNHQMMHTGEKP-YKCNECGKAFIERSNLVYH-QRNHTGE 846
Query: 777 PAKAHKCIFCGETFSTEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKH 825
K +KC+ CG+ F L H HS K Y C C K++ + L KH
Sbjct: 847 --KPYKCMECGKAFGRRSCLTKHQRIHSSEKPYKCNECGKSYISRSGLTKH 895
Score = 140 bits (353), Expect = 8e-33
Identities = 186/777 (23%), Positives = 279/777 (35%), Gaps = 153/777 (19%)
Query: 520 NQCSMGFLTESSLTEHIQQAHCSVGSAKL-ESPVVQPTQSFMEVYSCPYCTNSP----IF 574
N+C F SSL H Q H + + ES S + V+ + P +
Sbjct: 264 NECGKAFRVSSSLINH-QMIHTTEKPYRCNESGKAFHRGSLLTVHQIVHTRGKPYQCDVC 322
Query: 575 GSILKLTKHIKENHKNIPLAHSKKSKAEQSP-VSSDVEVSSPKRQRLSASANSISNGE-- 631
G I + +N L + ++S P + ++ S K L+ I GE
Sbjct: 323 GRIFR---------QNSDLVNHRRSHTGDKPYICNECGKSFSKSSHLAVHQR-IHTGEKP 372
Query: 632 YPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTH 691
Y CN+C FS S TH +H + C +C + F SL H +H
Sbjct: 373 YKCNRCGKCFSQSSSLATHQTVHTG--DKPYKCNECGKTFKRNSSLTAHHIIH--AGKKP 428
Query: 692 YVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYR 751
Y C+ C K F L +H + Y C C +VF + + H + H+ EK Y+
Sbjct: 429 YTCDVCGKVFYQNSQLVRHQIIHTGETPYKCNECGKVFFQRSRLAGHRRI-HTGEKP-YK 486
Query: 752 CTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCH--ITTHSKKYNC 809
C C F + + L VH + H G K +KC CG+ F+ L H I T K Y C
Sbjct: 487 CNECGKVFSQHSHLAVH-QRVHTGE--KPYKCNECGKAFNWGSLLTVHQRIHTGEKPYKC 543
Query: 810 KFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAP 869
C K F+ L H+R G P+ K GM+
Sbjct: 544 NVCGKVFNYGGYLSVHMR-------------CHTGEKPLHCNKC------GMVFTYYSCL 584
Query: 870 NSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGS 929
H+ + E Y C++CG + L HR R H GE
Sbjct: 585 ARHQR----MHTGEKPYKCNVCGKVFIDSGNLSIHR-RSHT---GEK------------P 624
Query: 930 HKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGT 989
+CN C + F + L H + H G K Y C CG+ + +LT+H V H+ +
Sbjct: 625 FQCNECGKVFSYYSCLARHRKIHTG-EKPYKCNDCGKAYTQRSSLTKHLVIHTGE-NPYH 682
Query: 990 CRICKMPLQSEEEFIEHCQMHPDLRNSLTG---FRCVVCMQTVTSTLELKIHGTFHMQKL 1046
C + E FI+ ++ RN TG +C C +T + L H H ++
Sbjct: 683 CN------EFGEAFIQSSKLARYHRNP-TGEKPHKCSECGRTFSHKTSLVYHQRRHTGEM 735
Query: 1047 AGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLVKLDVNGLPYGLCAGCMARSANGQVGG 1106
YKC C K F S L AR G
Sbjct: 736 P----------------YKCIECGKVFNSTTTL-----------------ARHRRIHTG- 761
Query: 1107 LAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGPRKGTQTSPVPRKK 1166
++P +C EC F L H + +K
Sbjct: 762 -------EKP---YKCNECGKVFRYRSGLARHWSIH--------------------TGEK 791
Query: 1167 TYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGMG 1226
Y+C +C F + H H E+ ++C C + F + L+ H H+ E
Sbjct: 792 PYKCNECGKAFRVRSILLNHQMMHTGEK--PYKCNECGKAFIERSNLVYHQRNHTGE--- 846
Query: 1227 GTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNHTMSQHA 1283
+KC C F + + L +H +H E K Y C++C + + ++ L H + +HA
Sbjct: 847 KPYKCMECGKAFGRRSCLTKH-QRIHSSE-KPYKCNECGKSYISRSGLTKHQI-KHA 900
Score = 139 bits (351), Expect = 1e-32
Identities = 191/821 (23%), Positives = 281/821 (34%), Gaps = 197/821 (23%)
Query: 186 KLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHK 245
K H +K Y +EC AF S L H H++ KP++C + F S L H H
Sbjct: 253 KTHIREKPYIGNECGKAFRVSSSLINHQMIHTTEKPYRCNESGKAFHRGSLLTVHQIVHT 312
Query: 246 KNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFV 305
+ K + CD C F Q +L H R +K + C C + F
Sbjct: 313 RGKP-------------YQCDVCGRIFRQNSDLVNH---RRSHTGDKPYI-CNECGKSFS 355
Query: 306 DENTLLAHIHQAHANQK-HKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSV 364
+ L H + H +K +KC C + FS
Sbjct: 356 KSSHLAVH-QRIHTGEKPYKCNRCGKCFSQ------------------------------ 384
Query: 365 ASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAV 424
S S AT + V G P Y C C K + ++
Sbjct: 385 -SSSLATHQT---VHTGDKP------------------------YKCNECGKTFKRNSSL 416
Query: 425 LEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNY 484
H+ IHA K + +TC +C Y ++ VR + ++ G + + CN
Sbjct: 417 TAHHI--IHAGK--KPYTCDVC---GKVFYQNSQLVR-------HQIIHTGE-TPYKCNE 461
Query: 485 CPEMFADINSLQEHIRV-------------------SHCGPNANPSDGNNAFFCNQCSMG 525
C ++F + L H R+ SH + G + CN+C
Sbjct: 462 CGKVFFQRSRLAGHRRIHTGEKPYKCNECGKVFSQHSHLAVHQRVHTGEKPYKCNECGKA 521
Query: 526 FLTESSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIK 585
F S LT H Q+ H E P Y C C +G L + H++
Sbjct: 522 FNWGSLLTVH-QRIHTG------EKP-----------YKCNVCGKVFNYGGYLSV--HMR 561
Query: 586 ENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFE 645
+ PL H K + S + QR+ Y CN C F +
Sbjct: 562 CHTGEKPL-HCNKCGMVFTYYS-----CLARHQRMHTGEK-----PYKCNVCGKVFIDSG 610
Query: 646 SFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVD 705
+ H + H + C +C + F L +H +H T Y C C K ++
Sbjct: 611 NLSIHRRSHTG--EKPFQCNECGKVFSYYSCLARHRKIH--TGEKPYKCNDCGKAYTQRS 666
Query: 706 DLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNE--KKMYRCTACNWDFRKEA 763
L KHL+ YHC E F LA H N +K ++C+ C F +
Sbjct: 667 SLTKHLVIHTGENPYHCNEFGEAFIQSSK----LARYHRNPTGEKPHKCSECGRTFSHKT 722
Query: 764 DLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCH--ITTHSKKYNCKFCSKAFHAIIL 821
L H + H G +KCI CG+ F++ L H I T K Y C C K F
Sbjct: 723 SLVYH-QRRHTGE--MPYKCIECGKVFNSTTTLARHRRIHTGEKPYKCNECGKVFRYRSG 779
Query: 822 LEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDA 881
L +H G P + A +L N + +
Sbjct: 780 LARHW-------------SIHTGEKPYKCNECGKAFRVRSILLNHQM----------MHT 816
Query: 882 SEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFS 941
E Y C+ CG A+ L H+ R+H GE +KC C + F
Sbjct: 817 GEKPYKCNECGKAFIERSNLVYHQ-RNHT---GEK------------PYKCMECGKAFGR 860
Query: 942 ENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHS 982
+ L +H + H K Y C CG+ + S LT+H++ H+
Sbjct: 861 RSCLTKHQRIH-SSEKPYKCNECGKSYISRSGLTKHQIKHA 900
Score = 107 bits (268), Expect = 6e-23
Identities = 73/290 (25%), Positives = 123/290 (42%), Gaps = 48/290 (16%)
Query: 64 ESIYTCDHCQQDFESLADLTDH-------RAHRCPGDGDDDPQLSWVASSPSSKDVASPT 116
E Y C+ C + + + LT H + C G+ +++ SS ++ +PT
Sbjct: 650 EKPYKCNDCGKAYTQRSSLTKHLVIHTGENPYHCNEFGE-----AFIQSSKLARYHRNPT 704
Query: 117 QMIGDGCDLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFK 176
GE+ P+ C C ++F + L H++ H+ ++P+KC C ++F
Sbjct: 705 -----------GEK------PHKCSECGRTFSHKTSLVYHQRRHTGEMPYKCIECGKVFN 747
Query: 177 HKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSS 236
+ RH ++HTG+K Y C+EC F L H H+ KP+KC C + F S
Sbjct: 748 STTTLARHRRIHTGEKPYKCNECGKVFRYRSGLARHWSIHTGEKPYKCNECGKAFRVRSI 807
Query: 237 LQSHMQAHKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQ 296
L +H H K + C+ C F + L H + EK +
Sbjct: 808 LLNHQMMHTGEKP-------------YKCNECGKAFIERSNLVYH---QRNHTGEKP-YK 850
Query: 297 CIHCPEVFVDENTLLAHIHQAHANQK-HKCPMCPEQFSSVEGVYCHLDSH 345
C+ C + F + L H + H+++K +KC C + + S G+ H H
Sbjct: 851 CMECGKAFGRRSCLTKH-QRIHSSEKPYKCNECGKSYISRSGLTKHQIKH 899
Score = 49.7 bits (117), Expect = 2e-05
Identities = 20/55 (36%), Positives = 31/55 (56%)
Query: 137 PYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGD 191
PY C C K+F R S L +H++IHS + P+KC C + + + +H H G+
Sbjct: 848 PYKCMECGKAFGRRSCLTKHQRIHSSEKPYKCNECGKSYISRSGLTKHQIKHAGE 902
>gi|157167158 zinc finger protein 808 [Homo sapiens]
Length = 903
Score = 204 bits (518), Expect = 6e-52
Identities = 173/701 (24%), Positives = 274/701 (39%), Gaps = 123/701 (17%)
Query: 137 PYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 196
PY C+ C KSF S L H ++H+ P+KC C ++F+ + H +HTG+K Y C
Sbjct: 286 PYKCKECGKSFSYKSSLTCHHRLHTGVKPYKCNECGKVFRQNSALVIHKAIHTGEKPYKC 345
Query: 197 HECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEK 256
+EC AF++ HL H + H+ KP+KC +C++ F+ S L +H + H K +
Sbjct: 346 NECGKAFNQQSHLSRHQRLHTGVKPYKCKICEKAFACHSYLANHTRIHSGEKTYKCNECG 405
Query: 257 EA---------------KKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCP 301
+A + + C+ C+ FSQ LE+H + EK +C C
Sbjct: 406 KAFNHQSSLARHHILHTGEKPYKCEECDKVFSQKSTLERH---KRIHTGEK-PYKCKVCD 461
Query: 302 EVFVDENTLLAHIHQAHANQK-HKCPMCPEQFSSVEGVYCH--LDSHRQPDSSNHSVSPD 358
F N+ LA + H +K +KC C + FS + CH L S +P N
Sbjct: 462 TAFTC-NSQLARHRRIHTGEKTYKCNECRKTFSRRSSLLCHRRLHSGEKPYKCNQC---- 516
Query: 359 PVLGSVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRD 418
+ R S L +++ + Y C C+K
Sbjct: 517 ---------------GNTFRHRAS--------LVYHRRLHT-----LEKSYKCTVCNK-V 547
Query: 419 FNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNIS 478
F +VL +H + A KP + C C + +L+ H R+LH
Sbjct: 548 FMRNSVLAVHTRIHTAKKP---YKCNECGKAFNQQSHLSRH-RRLHTGE----------K 593
Query: 479 AFHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQ 538
+ C C ++F ++L+ H R+ G + C C F S L H +
Sbjct: 594 PYKCEACDKVFGQKSALESHKRI---------HTGEKPYRCQVCDTAFTWNSQLARHTR- 643
Query: 539 AHCSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKK 598
+ + Y C C + + S L + + K+ K
Sbjct: 644 -----------------IHTGEKTYKCNECGKTFSYKSSLVWHRRLHGGEKSYKCKVCDK 686
Query: 599 SKAEQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELL 658
+ +S V+ + S + Y CN+C FSN S H ++H
Sbjct: 687 AFVCRSYVAKHTRIHSGMK-------------PYKCNECSKTFSNRSSLVCHRRIHSG-- 731
Query: 659 LRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHT-F 717
+ C +C + F + +LL H +H + Y C C F L H +HT
Sbjct: 732 EKPYKCSECSKTFSQKATLLCHRRLH--SGEKPYKCNDCGNTFRHWSSLVYH-RRLHTGE 788
Query: 718 VLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNP 777
Y CT+C + F + H+ + H+ EK Y+C C F +++ L +H +
Sbjct: 789 KSYKCTVCDKAFVRNSYLARHIRI-HTAEKP-YKCNECGKAFNEQSHLS---RHHRIHTG 843
Query: 778 AKAHKCIFCGETFSTEVELQCH--ITTHSKKYNCKFCSKAF 816
K +KC C + FS + L+ H I T K Y C C KAF
Sbjct: 844 EKPYKCEACDKVFSRKSHLKRHRIIHTGEKPYKCNECGKAF 884
Score = 190 bits (483), Expect = 7e-48
Identities = 156/634 (24%), Positives = 240/634 (37%), Gaps = 112/634 (17%)
Query: 137 PYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 196
PY C+ C+K+F SYL H +IHS + +KC C + F H+ S RH LHTG+K Y C
Sbjct: 370 PYKCKICEKAFACHSYLANHTRIHSGEKTYKCNECGKAFNHQSSLARHHILHTGEKPYKC 429
Query: 197 HECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEK 256
EC+ FS+ L+ H + H+ KP+KC VC F+ S L H + H K
Sbjct: 430 EECDKVFSQKSTLERHKRIHTGEKPYKCKVCDTAFTCNSQLARHRRIHTGEK-------- 481
Query: 257 EAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQ 316
+ C+ C TFS+ L H R EK +C C F +L+ H
Sbjct: 482 -----TYKCNECRKTFSRRSSLLCH---RRLHSGEK-PYKCNQCGNTFRHRASLVYHRRL 532
Query: 317 AHANQKHKCPMCPEQF--SSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDS 374
+ +KC +C + F +SV V+ + + ++P N G + S
Sbjct: 533 HTLEKSYKCTVCNKVFMRNSVLAVHTRIHTAKKPYKCNE-------CGKAFNQQSHL-SR 584
Query: 375 SASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHA 434
+ G P Y C C K F + LE H +
Sbjct: 585 HRRLHTGEKP------------------------YKCEACDK-VFGQKSALESHKRIHTG 619
Query: 435 DKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINS 494
+KP + CQ+C + L H R +H + CN C + F+ +S
Sbjct: 620 EKP---YRCQVCDTAFTWNSQLARHTR-IHTGE----------KTYKCNECGKTFSYKSS 665
Query: 495 LQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQ 554
L H R+ G ++ C C F+ S + +H +
Sbjct: 666 LVWHRRL---------HGGEKSYKCKVCDKAFVCRSYVAKHTR----------------- 699
Query: 555 PTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSS 614
S M+ Y C C+ + S L + I K + K+ ++++ + + S
Sbjct: 700 -IHSGMKPYKCNECSKTFSNRSSLVCHRRIHSGEKPYKCSECSKTFSQKATLLCHRRLHS 758
Query: 615 PKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQ 674
++ Y CN C F ++ S H +LH + C C + F
Sbjct: 759 GEK-------------PYKCNDCGNTFRHWSSLVYHRRLHTG--EKSYKCTVCDKAFVRN 803
Query: 675 ESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVS 734
L +H+ +H T Y C C K F+ L +H Y C C +VF K
Sbjct: 804 SYLARHIRIH--TAEKPYKCNECGKAFNEQSHLSRHHRIHTGEKPYKCEACDKVFSRKSH 861
Query: 735 IQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVH 768
++ H + H+ EK Y+C C F + L H
Sbjct: 862 LKRHRII-HTGEKP-YKCNECGKAFSDRSTLIHH 893
Score = 187 bits (476), Expect = 4e-47
Identities = 193/788 (24%), Positives = 286/788 (36%), Gaps = 144/788 (18%)
Query: 138 YPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCH 197
+PC K+F S L++H+ H +KC C +LF HK+ H + HTG+K Y C
Sbjct: 231 FPCNESGKAFNCSSLLRKHQIPHLGDKQYKCDVCGKLFNHKQYLACHRRCHTGEKPYKCK 290
Query: 198 ECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNK--------- 248
EC +FS L H + H+ KP+KC C + F S+L H H K
Sbjct: 291 ECGKSFSYKSSLTCHHRLHTGVKPYKCNECGKVFRQNSALVIHKAIHTGEKPYKCNECGK 350
Query: 249 -----EHLAKSEK-EAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPE 302
HL++ ++ + C CE F+ L H S + +C C +
Sbjct: 351 AFNQQSHLSRHQRLHTGVKPYKCKICEKAFACHSYLANHTRIH----SGEKTYKCNECGK 406
Query: 303 VFVDENTLLAHIHQAHANQK-HKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVL 361
F +++L H H H +K +KC C + FS + H H P
Sbjct: 407 AFNHQSSLARH-HILHTGEKPYKCEECDKVFSQKSTLERHKRIH---------TGEKPYK 456
Query: 362 GSVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNS 421
V + A R T + T Y C C ++ F+
Sbjct: 457 CKVCDTAFTCNSQLARHRRIHTGEKT---------------------YKCNEC-RKTFSR 494
Query: 422 LAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFH 481
+ L H + +KP + C C ++ +L H R+LH ++
Sbjct: 495 RSSLLCHRRLHSGEKP---YKCNQCGNTFRHRASLVYH-RRLHTLE----------KSYK 540
Query: 482 CNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHC 541
C C ++F + L H R+ + CN+C F +S L+ H ++ H
Sbjct: 541 CTVCNKVFMRNSVLAVHTRI---------HTAKKPYKCNECGKAFNQQSHLSRH-RRLHT 590
Query: 542 SVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKA 601
E P Y C C +FG K E+HK I
Sbjct: 591 G------EKP-----------YKCEAC--DKVFGQ-----KSALESHKRI--------HT 618
Query: 602 EQSPVSSDVEVSSPKRQRLSASANSISNGE--YPCNQCDLKFSNFESFQTHLKLHLELLL 659
+ P V ++ A I GE Y CN+C FS S H +LH
Sbjct: 619 GEKPYRCQVCDTAFTWNSQLARHTRIHTGEKTYKCNECGKTFSYKSSLVWHRRLHGG--E 676
Query: 660 RKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVL 719
+ C C + F + + +H +H + Y C C K FS+ L H
Sbjct: 677 KSYKCKVCDKAFVCRSYVAKHTRIH--SGMKPYKCNECSKTFSNRSSLVCHRRIHSGEKP 734
Query: 720 YHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAK 779
Y C+ C + F K ++ H + HS EK Y+C C FR + L V H L K
Sbjct: 735 YKCSECSKTFSQKATLLCHRRL-HSGEKP-YKCNDCGNTFRHWSSL---VYHRRLHTGEK 789
Query: 780 AHKCIFCGETFSTEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHLREKHCVFDAAT 837
++KC C + F L HI H+ K Y C C KAF+ + HL H +
Sbjct: 790 SYKCTVCDKAFVRNSYLARHIRIHTAEKPYKCNECGKAFNE----QSHLSRHHRIH---- 841
Query: 838 ENGTANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTM 897
G P K E D + SH + E Y C+ CG A++
Sbjct: 842 -----TGEKPY---KCEACD-------KVFSRKSHLKRHRIIHTGEKPYKCNECGKAFSD 886
Query: 898 EVLLQNHR 905
L +H+
Sbjct: 887 RSTLIHHQ 894
Score = 169 bits (428), Expect = 2e-41
Identities = 182/800 (22%), Positives = 282/800 (35%), Gaps = 167/800 (20%)
Query: 480 FHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQA 539
+ C+ C ++F L H R G + C +C F +SSLT H +
Sbjct: 259 YKCDVCGKLFNHKQYLACHRRCH---------TGEKPYKCKECGKSFSYKSSLTCH-HRL 308
Query: 540 HCSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKS 599
H V + Y C C S L + K I K K+
Sbjct: 309 HTGV-----------------KPYKCNECGKVFRQNSALVIHKAIHTGEKPYKCNECGKA 351
Query: 600 KAEQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLL 659
+QS +S + QRL Y C C+ F+ H ++H
Sbjct: 352 FNQQSHLS--------RHQRLHTGVKP-----YKCKICEKAFACHSYLANHTRIHSGEKT 398
Query: 660 RKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVL 719
K C +C + F+ Q SL +H +H T Y CE CDK FS L++H
Sbjct: 399 YK--CNECGKAFNHQSSLARHHILH--TGEKPYKCEECDKVFSQKSTLERHKRIHTGEKP 454
Query: 720 YHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAK 779
Y C +C F + H + H+ EK Y+C C F + + L H + H G K
Sbjct: 455 YKCKVCDTAFTCNSQLARHRRI-HTGEKT-YKCNECRKTFSRRSSLLCH-RRLHSGE--K 509
Query: 780 AHKCIFCGETFSTEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHLREKHCVFDAAT 837
+KC CG TF L H H+ K Y C C+K F +L H R
Sbjct: 510 PYKCNQCGNTFRHRASLVYHRRLHTLEKSYKCTVCNKVFMRNSVLAVHTRIH-------- 561
Query: 838 ENGTANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTM 897
KK + G SH + + E Y C+ C +
Sbjct: 562 -----------TAKKPYKCNECGKAFNQ----QSHLSRHRRLHTGEKPYKCEACDKVFGQ 606
Query: 898 EVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAK 957
+ L++H+ I GE ++C VC F + L H + H G K
Sbjct: 607 KSALESHK----RIHTGEKP------------YRCQVCDTAFTWNSQLARHTRIHTGE-K 649
Query: 958 HYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSL 1017
Y C CG+ F +L H+ H + C++C +H ++H ++
Sbjct: 650 TYKCNECGKTFSYKSSLVWHRRLHGGE-KSYKCKVCDKAFVCRSYVAKHTRIHSGMKP-- 706
Query: 1018 TGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQ 1077
++C C +T ++ L H H +K YKC+ C K F K
Sbjct: 707 --YKCNECSKTFSNRSSLVCHRRIHSG----------------EKPYKCSECSKTFSQKA 748
Query: 1078 DLVKLDVNGLPYGLCAGCMARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLES 1137
L+ C R +G+ +P +C +C F L
Sbjct: 749 TLL--------------CHRRLHSGE-----------KP---YKCNDCGNTFRHWSSLVY 780
Query: 1138 HMQVDHRDLTPETSGPRKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEGIN 1197
H ++ + K+Y+C C F + H+ H E+
Sbjct: 781 HRRLHTGE--------------------KSYKCTVCDKAFVRNSYLARHIRIHTAEKP-- 818
Query: 1198 HECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDK 1257
++C C + F+ + L H H+ E +KC C VF + + L++H G+ K
Sbjct: 819 YKCNECGKAFNEQSHLSRHHRIHTGEK---PYKCEACDKVFSRKSHLKRHRIIHTGE--K 873
Query: 1258 IYDCSQCPQKFFFQTELQNH 1277
Y C++C + F ++ L +H
Sbjct: 874 PYKCNECGKAFSDRSTLIHH 893
Score = 166 bits (420), Expect = 1e-40
Identities = 191/817 (23%), Positives = 280/817 (34%), Gaps = 183/817 (22%)
Query: 409 YSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHA 468
Y C C K FN L H + +KP + C+ C S +L H H+ H
Sbjct: 259 YKCDVCGKL-FNHKQYLACHRRCHTGEKP---YKCKECGKSFSYKSSLTCH----HRLHT 310
Query: 469 YPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLT 528
+ + CN C ++F ++L H + G + CN+C F
Sbjct: 311 -------GVKPYKCNECGKVFRQNSALVIHKAIH---------TGEKPYKCNECGKAFNQ 354
Query: 529 ESSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENH 588
+S L+ H Q+ H V + Y C C + S L NH
Sbjct: 355 QSHLSRH-QRLHTGV-----------------KPYKCKICEKAFACHSYL-------ANH 389
Query: 589 KNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQ 648
I HS + Y CN+C F++ S
Sbjct: 390 TRI---HSGEK-------------------------------TYKCNECGKAFNHQSSLA 415
Query: 649 THLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQ 708
H LH + C +C + F + +L +H +H T Y C+ CD F+ L
Sbjct: 416 RHHILHTG--EKPYKCEECDKVFSQKSTLERHKRIH--TGEKPYKCKVCDTAFTCNSQLA 471
Query: 709 KHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVH 768
+H Y C C++ F + S+ H + HS EK Y+C C FR A L
Sbjct: 472 RHRRIHTGEKTYKCNECRKTFSRRSSLLCHRRL-HSGEKP-YKCNQCGNTFRHRASL--- 526
Query: 769 VKHSHLGNPAKAHKCIFCGETFSTEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHL 826
V H L K++KC C + F L H H+ K Y C C KAF+ L +H
Sbjct: 527 VYHRRLHTLEKSYKCTVCNKVFMRNSVLAVHTRIHTAKKPYKCNECGKAFNQQSHLSRHR 586
Query: 827 REKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMY 886
R G P K E D + A SH+ + E Y
Sbjct: 587 R-------------LHTGEKPY---KCEACD---KVFGQKSALESHKR----IHTGEKPY 623
Query: 887 GCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLR 946
C +C A+T L H I GE ++KCN C +TF ++ L
Sbjct: 624 RCQVCDTAFTWNSQLARHT----RIHTGEK------------TYKCNECGKTFSYKSSLV 667
Query: 947 EHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEH 1006
H + H G K Y C +C + F + +H HS + C C + + H
Sbjct: 668 WHRRLH-GGEKSYKCKVCDKAFVCRSYVAKHTRIHS-GMKPYKCNECSKTFSNRSSLVCH 725
Query: 1007 CQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKC 1066
++H + ++C C +T + L H H +K YKC
Sbjct: 726 RRIH----SGEKPYKCSECSKTFSQKATLLCHRRLHSG----------------EKPYKC 765
Query: 1067 ALCLKEFRSKQDLV---KLDVNGLPYGLCAGCMARSANGQVGGLAPPEPADRPCAGLRCP 1123
C FR LV +L Y A N + A++P +C
Sbjct: 766 NDCGNTFRHWSSLVYHRRLHTGEKSYKCTVCDKAFVRNSYLARHIRIHTAEKP---YKCN 822
Query: 1124 ECSVKFESAEDLESHMQVDHRDLTPETSGPRKGTQTSPVPRKKTYQCIKCQMTFENEREI 1183
EC F +SH+ HR T E K Y+C C F + +
Sbjct: 823 ECGKAFNE----QSHLSRHHRIHTGE----------------KPYKCEACDKVFSRKSHL 862
Query: 1184 QIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEH 1220
+ H H E+ ++C C + F + L+ H H
Sbjct: 863 KRHRIIHTGEK--PYKCNECGKAFSDRSTLIHHQAIH 897
Score = 166 bits (419), Expect = 2e-40
Identities = 180/734 (24%), Positives = 266/734 (36%), Gaps = 138/734 (18%)
Query: 583 HIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFS 642
HI N+ N PL S P++Q + S +PCN+ F+
Sbjct: 203 HISNNYGNNPLNSSLL----------------PQKQEVHMREKS-----FPCNESGKAFN 241
Query: 643 NFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFS 702
+ H HL ++ C C + F+ ++ L H H T Y C+ C K FS
Sbjct: 242 CSSLLRKHQIPHLGD--KQYKCDVCGKLFNHKQYLACHRRCH--TGEKPYKCKECGKSFS 297
Query: 703 SVDDLQKHLLDMHTFVL-YHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRK 761
L H +HT V Y C C +VF ++ +H A+ H+ EK Y+C C F +
Sbjct: 298 YKSSLTCHHR-LHTGVKPYKCNECGKVFRQNSALVIHKAI-HTGEKP-YKCNECGKAFNQ 354
Query: 762 EADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHITTHS--KKYNCKFCSKAFHAI 819
++ L +H L K +KC C + F+ L H HS K Y C C KAF+
Sbjct: 355 QSHLS---RHQRLHTGVKPYKCKICEKAFACHSYLANHTRIHSGEKTYKCNECGKAFNHQ 411
Query: 820 ILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDV 879
L +H H + G P ++ + Q L+ + +
Sbjct: 412 SSLARH----HILH---------TGEKPYKCEECDKVFSQKSTLERHKR----------I 448
Query: 880 DASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTF 939
E Y C +C A+T L HR I GE ++KCN C +TF
Sbjct: 449 HTGEKPYKCKVCDTAFTCNSQLARHR----RIHTGEK------------TYKCNECRKTF 492
Query: 940 FSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQS 999
+ L H + H G K Y C CG F +L H+ H+ + C +C
Sbjct: 493 SRRSSLLCHRRLHSGE-KPYKCNQCGNTFRHRASLVYHRRLHTLE-KSYKCTVCNKVFMR 550
Query: 1000 EEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQG 1059
H ++H + ++C C + L H H
Sbjct: 551 NSVLAVHTRIH----TAKKPYKCNECGKAFNQQSHLSRHRRLHTG--------------- 591
Query: 1060 LQKLYKCALCLKEFRSKQDLV---KLDVNGLPYGLCAGCMARSANGQVGGLAPPEPADRP 1116
+K YKC C K F K L ++ PY A + N Q+ ++
Sbjct: 592 -EKPYKCEACDKVFGQKSALESHKRIHTGEKPYRCQVCDTAFTWNSQLARHTRIHTGEKT 650
Query: 1117 CAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGPRKGTQTSPVPRKKT--------Y 1168
+C EC F L H ++ + + + K K T Y
Sbjct: 651 ---YKCNECGKTFSYKSSLVWHRRLHGGEKSYKCKVCDKAFVCRSYVAKHTRIHSGMKPY 707
Query: 1169 QCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFE----- 1223
+C +C TF N + H H E+ ++C C++ F A LLCH HS E
Sbjct: 708 KCNECSKTFSNRSSLVCHRRIHSGEKP--YKCSECSKTFSQKATLLCHRRLHSGEKPYKC 765
Query: 1224 -GMGGTF-------------------KCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQ 1263
G TF KC VC FV+ + L +HI +H E K Y C++
Sbjct: 766 NDCGNTFRHWSSLVYHRRLHTGEKSYKCTVCDKAFVRNSYLARHI-RIHTAE-KPYKCNE 823
Query: 1264 CPQKFFFQTELQNH 1277
C + F Q+ L H
Sbjct: 824 CGKAFNEQSHLSRH 837
Score = 135 bits (339), Expect = 3e-31
Identities = 142/607 (23%), Positives = 212/607 (34%), Gaps = 131/607 (21%)
Query: 677 LLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQ 736
L Q VH S + C K F+ L+KH + Y C +C ++F+ K +
Sbjct: 218 LPQKQEVHMREKS--FPCNESGKAFNCSSLLRKHQIPHLGDKQYKCDVCGKLFNHKQYLA 275
Query: 737 VHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVEL 796
H H+ EK Y+C C F ++ L H + L K +KC CG+ F L
Sbjct: 276 CHRRC-HTGEKP-YKCKECGKSFSYKSSLTCHHR---LHTGVKPYKCNECGKVFRQNSAL 330
Query: 797 QCHITTHS--KKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAE 854
H H+ K Y C C KAF+ L +H R GV P K E
Sbjct: 331 VIHKAIHTGEKPYKCNECGKAFNQQSHLSRHQR-------------LHTGVKPYKCKICE 377
Query: 855 PADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPG 914
A A +S+ A+ + + E Y C+ CG A+ + L H H + G
Sbjct: 378 KAF----------ACHSYLANHTRIHSGEKTYKCNECGKAFNHQSSLARH----HILHTG 423
Query: 915 EDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTL 974
E +KC C + F ++ L H + H G K Y C +C F L
Sbjct: 424 EKP------------YKCEECDKVFSQKSTLERHKRIHTGE-KPYKCKVCDTAFTCNSQL 470
Query: 975 TEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLE 1034
H+ H+ T C C+ + H ++H + ++C C T
Sbjct: 471 ARHRRIHTGE-KTYKCNECRKTFSRRSSLLCHRRLHSGEKP----YKCNQCGNTFRHRAS 525
Query: 1035 LKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLV---KLDVNGLPYGL 1091
L H H L+K YKC +C K F L ++ PY
Sbjct: 526 LVYHRRLHT----------------LEKSYKCTVCNKVFMRNSVLAVHTRIHTAKKPY-- 567
Query: 1092 CAGCMARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETS 1151
+C EC F L H ++ +
Sbjct: 568 -----------------------------KCNECGKAFNQQSHLSRHRRLHTGE------ 592
Query: 1152 GPRKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPA 1211
K Y+C C F + ++ H H E+ + C++C+ F +
Sbjct: 593 --------------KPYKCEACDKVFGQKSALESHKRIHTGEKP--YRCQVCDTAFTWNS 636
Query: 1212 KLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQ 1271
+L H H+ E T+KC C F + L H +HG E K Y C C + F +
Sbjct: 637 QLARHTRIHTGEK---TYKCNECGKTFSYKSSLVWHR-RLHGGE-KSYKCKVCDKAFVCR 691
Query: 1272 TELQNHT 1278
+ + HT
Sbjct: 692 SYVAKHT 698
Score = 117 bits (293), Expect = 7e-26
Identities = 66/223 (29%), Positives = 103/223 (46%), Gaps = 19/223 (8%)
Query: 138 YPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCH 197
Y C+ CDK+F+ SY+ +H +IHS P+KC CS+ F ++ S H ++H+G+K Y C
Sbjct: 679 YKCKVCDKAFVCRSYVAKHTRIHSGMKPYKCNECSKTFSNRSSLVCHRRIHSGEKPYKCS 738
Query: 198 ECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEH------- 250
EC FS+ L H + HS KP+KC C F SSL H + H K +
Sbjct: 739 ECSKTFSQKATLLCHRRLHSGEKPYKCNDCGNTFRHWSSLVYHRRLHTGEKSYKCTVCDK 798
Query: 251 -------LAKSEK-EAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPE 302
LA+ + + + C+ C F++ L +H H + + +C C +
Sbjct: 799 AFVRNSYLARHIRIHTAEKPYKCNECGKAFNEQSHLSRH----HRIHTGEKPYKCEACDK 854
Query: 303 VFVDENTLLAHIHQAHANQKHKCPMCPEQFSSVEGVYCHLDSH 345
VF ++ L H + +KC C + FS + H H
Sbjct: 855 VFSRKSHLKRHRIIHTGEKPYKCNECGKAFSDRSTLIHHQAIH 897
Score = 78.2 bits (191), Expect = 5e-14
Identities = 35/84 (41%), Positives = 46/84 (54%)
Query: 137 PYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 196
PY C C K+F S+L RH +IH+ + P+KC C ++F K RH +HTG+K Y C
Sbjct: 818 PYKCNECGKAFNEQSHLSRHHRIHTGEKPYKCEACDKVFSRKSHLKRHRIIHTGEKPYKC 877
Query: 197 HECEAAFSRSDHLKIHLKTHSSSK 220
+EC AFS L H H K
Sbjct: 878 NECGKAFSDRSTLIHHQAIHGIGK 901
>gi|25014093 zinc finger protein 585B [Homo sapiens]
Length = 769
Score = 195 bits (495), Expect = 3e-49
Identities = 174/682 (25%), Positives = 250/682 (36%), Gaps = 143/682 (20%)
Query: 138 YPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCH 197
Y C C K F S L HE+IH+ + +CT C + F K + H K+HTG++ Y C
Sbjct: 214 YECSECGKGFPYNSDLSIHEKIHTGERHHECTDCGKAFTQKSTLKIHQKIHTGERSYICI 273
Query: 198 ECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEKE 257
EC AF + L H + HS KP++C C + F S S LQ H + H + K
Sbjct: 274 ECGQAFIQKTQLIAHRRIHSGEKPYECNNCGKSFISKSQLQVHQRVHTRVK--------- 324
Query: 258 AKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQA 317
++C FS L H Q EK+ + C C + F + L+ H +
Sbjct: 325 ----PYICTEYGKVFSNNSNLITH---EKIQSREKSSI-CTECGKAFTYRSELIIH-QRI 375
Query: 318 HANQK-HKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDSSA 376
H +K ++C C F+ + H H S + +A + A +
Sbjct: 376 HTGEKPYECSDCGRAFTQKSALTVHQRIH------TGEKSYICMKCGLAFIRKAHLITHQ 429
Query: 377 SVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHADK 436
+ G P Y C +C K F S + L +H + +K
Sbjct: 430 IIHTGEKP------------------------YKCGHCGKL-FTSKSQLHVHKRIHTGEK 464
Query: 437 PQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINSLQ 496
P + C C + NL H +K H ++ C+ C + F + L
Sbjct: 465 P---YVCNKCGKAFTNRSNLITH-QKTHTGE----------KSYICSKCGKAFTQRSDLI 510
Query: 497 EHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPT 556
H R+ G + CN C F +S+L H Q
Sbjct: 511 THQRI---------HTGEKPYECNTCGKAFTQKSNLNIH------------------QKI 543
Query: 557 QSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPK 616
+ Y C C + N K+I + H K E+
Sbjct: 544 HTGERQYECHECGKA--------------FNQKSILIVHQKIHTGEK------------- 576
Query: 617 RQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQES 676
Y C +C F +F TH ++H + C C + F S+
Sbjct: 577 --------------PYVCTECGRAFIRKSNFITHQRIHTG--EKPYECSDCGKSFTSKSQ 620
Query: 677 LLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQ 736
LL H VH T YVC C K FS +L KH Y C+ C + F K +
Sbjct: 621 LLVHQPVH--TGEKPYVCAECGKAFSGRSNLSKHQKTHTGEKPYICSECGKTFRQKSELI 678
Query: 737 VHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVEL 796
H + H+ EK Y C+ C F K++ LQVH + H G K + C CG+ FS L
Sbjct: 679 THHRI-HTGEKP-YECSDCGKSFTKKSQLQVH-QRIHTGE--KPYVCAECGKAFSNRSNL 733
Query: 797 QCHITTHS--KKYNCKFCSKAF 816
H TTH+ K Y C C K F
Sbjct: 734 NKHQTTHTGDKPYKCGICGKGF 755
Score = 152 bits (383), Expect = 3e-36
Identities = 166/668 (24%), Positives = 253/668 (37%), Gaps = 111/668 (16%)
Query: 632 YPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTH 691
Y C +C F F TH K H+ + C +C + F SL +H +H T
Sbjct: 158 YVCIECGRAFVQKPEFITHQKTHMRE--KPPKCNECGKSFFQVSSLFRHHRIH--TGEKL 213
Query: 692 YVCESCDKQFSSVDDLQKHLLDMHTFVLYH-CTLCQEVFDSKVSIQVHLAVKHSNEKKMY 750
Y C C K F DL H +HT +H CT C + F K ++++H + H+ E+ Y
Sbjct: 214 YECSECGKGFPYNSDLSIHE-KIHTGERHHECTDCGKAFTQKSTLKIHQKI-HTGERS-Y 270
Query: 751 RCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHITTHS--KKYN 808
C C F ++ L + H + + K ++C CG++F ++ +LQ H H+ K Y
Sbjct: 271 ICIECGQAFIQKTQL---IAHRRIHSGEKPYECNNCGKSFISKSQLQVHQRVHTRVKPYI 327
Query: 809 CKFCSKAFHA---IILLEK-HLREKHCVFDAATENGTANGVPP---------MATKKAEP 855
C K F +I EK REK + TE G A K E
Sbjct: 328 CTEYGKVFSNNSNLITHEKIQSREKSSI---CTECGKAFTYRSELIIHQRIHTGEKPYEC 384
Query: 856 ADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGE 915
+D G A H+ + E Y C CG A+ + L H++ I GE
Sbjct: 385 SDC-GRAFTQKSALTVHQR----IHTGEKSYICMKCGLAFIRKAHLITHQI----IHTGE 435
Query: 916 DDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLT 975
+KC C + F S++ L H + H G K Y+C CG+ F + L
Sbjct: 436 KP------------YKCGHCGKLFTSKSQLHVHKRIHTGE-KPYVCNKCGKAFTNRSNLI 482
Query: 976 EHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLEL 1035
H+ TH+ + C C + I H ++H + + C C + T L
Sbjct: 483 THQKTHTGE-KSYICSKCGKAFTQRSDLITHQRIHTGEKP----YECNTCGKAFTQKSNL 537
Query: 1036 KIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLV---KLDVNGLPYGLC 1092
IH H ++ Y+C C K F K L+ K+ PY +C
Sbjct: 538 NIHQKIHTG----------------ERQYECHECGKAFNQKSILIVHQKIHTGEKPY-VC 580
Query: 1093 AGC---MARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPE 1149
C R +N ++P C +C F S L H V +
Sbjct: 581 TECGRAFIRKSNFITHQRI--HTGEKP---YECSDCGKSFTSKSQLLVHQPVHTGE---- 631
Query: 1150 TSGPRKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDS 1209
K Y C +C F + H H E+ + C C + F
Sbjct: 632 ----------------KPYVCAECGKAFSGRSNLSKHQKTHTGEKP--YICSECGKTFRQ 673
Query: 1210 PAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFF 1269
++L+ H H+ E ++C C F + ++LQ H +H E K Y C++C + F
Sbjct: 674 KSELITHHRIHTGEK---PYECSDCGKSFTKKSQLQVHQ-RIHTGE-KPYVCAECGKAFS 728
Query: 1270 FQTELQNH 1277
++ L H
Sbjct: 729 NRSNLNKH 736
Score = 144 bits (362), Expect = 7e-34
Identities = 169/775 (21%), Positives = 268/775 (34%), Gaps = 202/775 (26%)
Query: 482 CNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHC 541
CN C + F ++SL H R+ G + C++C GF S L+ H
Sbjct: 188 CNECGKSFFQVSSLFRHHRIH---------TGEKLYECSECGKGFPYNSDLSIH------ 232
Query: 542 SVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKA 601
+ + + C C + S LK+ H K
Sbjct: 233 ------------EKIHTGERHHECTDCGKAFTQKSTLKI--------------HQKIHTG 266
Query: 602 EQSPVSSDVEVSSPKRQRLSASANSISNGE--YPCNQCDLKFSNFESFQTHLKLHLELLL 659
E+S + + + ++ +L A I +GE Y CN C F + Q H ++H +
Sbjct: 267 ERSYICIECGQAFIQKTQLIAHRR-IHSGEKPYECNNCGKSFISKSQLQVHQRVHTRV-- 323
Query: 660 RKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVL 719
+ C + + F + +L+ H + S+ +C C K F+ +L H
Sbjct: 324 KPYICTEYGKVFSNNSNLITHEKIQSREKSS--ICTECGKAFTYRSELIIHQRIHTGEKP 381
Query: 720 YHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAK 779
Y C+ C F K ++ VH + H+ EK Y C C F ++A L + H + K
Sbjct: 382 YECSDCGRAFTQKSALTVHQRI-HTGEKS-YICMKCGLAFIRKAHL---ITHQIIHTGEK 436
Query: 780 AHKCIFCGETFSTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFDAAT 837
+KC CG+ F+++ +L H I T K Y C C KAF
Sbjct: 437 PYKCGHCGKLFTSKSQLHVHKRIHTGEKPYVCNKCGKAF--------------------- 475
Query: 838 ENGTANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTM 897
S+ + E Y C CG A+T
Sbjct: 476 ------------------------------TNRSNLITHQKTHTGEKSYICSKCGKAFTQ 505
Query: 898 EVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAK 957
L H+ I GE ++CN C + F ++ L H + H G +
Sbjct: 506 RSDLITHQ----RIHTGEKP------------YECNTCGKAFTQKSNLNIHQKIHTG-ER 548
Query: 958 HYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSL 1017
Y C CG+ F L H+ H+ C C + FI H ++H +
Sbjct: 549 QYECHECGKAFNQKSILIVHQKIHTGE-KPYVCTECGRAFIRKSNFITHQRIHTGEK--- 604
Query: 1018 TGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQ 1077
+ C C ++ TS +L +H H +K Y CA C K F +
Sbjct: 605 -PYECSDCGKSFTSKSQLLVHQPVHTG----------------EKPYVCAECGKAFSGRS 647
Query: 1078 DLVKLDVNGLPYGLCAGCMARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLES 1137
+L K ++P C EC F +L +
Sbjct: 648 NLSKHQ-------------------------KTHTGEKPYI---CSECGKTFRQKSELIT 679
Query: 1138 HMQVDHRDLTPETSGPRKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEGIN 1197
H HR T E K Y+C C +F + ++Q+H H E+
Sbjct: 680 H----HRIHTGE----------------KPYECSDCGKSFTKKSQLQVHQRIHTGEK--P 717
Query: 1198 HECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVH 1252
+ C C + F + + L H H+ + +KC +C FV Q+ +F+VH
Sbjct: 718 YVCAECGKAFSNRSNLNKHQTTHTGD---KPYKCGICGKGFV-----QKSVFSVH 764
Score = 140 bits (353), Expect = 8e-33
Identities = 178/824 (21%), Positives = 287/824 (34%), Gaps = 177/824 (21%)
Query: 173 RLFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFS 232
++ +K + + K+++G+K Y C E +F+ K+HLK + K +
Sbjct: 109 KIIGYKPASSQDQKIYSGEKSYECAEFGKSFTWKSQFKVHLKVPTGEKLY---------- 158
Query: 233 STSSLQSHMQAHKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEK 292
+C C F Q E H T + K
Sbjct: 159 -------------------------------VCIECGRAFVQKPEFITHQKTHMREKPPK 187
Query: 293 ADLQCIHCPEVFVDENTLLAHIHQAHANQK-HKCPMCPEQFSSVEGVYCHLDSHRQPDSS 351
C C + F ++L H H+ H +K ++C C + F + H H
Sbjct: 188 ----CNECGKSFFQVSSLFRH-HRIHTGEKLYECSECGKGFPYNSDLSIHEKIHT---GE 239
Query: 352 NHSVSPDPVLGSVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSC 411
H D + T STLK +K+ + Y C
Sbjct: 240 RHHECTD-------------------CGKAFTQKSTLKI---HQKIHTGERS-----YIC 272
Query: 412 PYCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPV 471
C + F L H + +KP + C C S + L H R + Y
Sbjct: 273 IECGQA-FIQKTQLIAHRRIHSGEKPYE---CNNCGKSFISKSQLQVHQRVHTRVKPYIC 328
Query: 472 MQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGP----------NANPSDGNNAFFCNQ 521
++G + + + N I S ++ + CG + G + C+
Sbjct: 329 TEYGKVFSNNSNLITH--EKIQSREKSSICTECGKAFTYRSELIIHQRIHTGEKPYECSD 386
Query: 522 CSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLT 581
C F +S+LT H Q+ H S Y C C + I + L
Sbjct: 387 CGRAFTQKSALTVH-QRIHTGEKS-----------------YICMKCGLAFIRKAHLITH 428
Query: 582 KHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKF 641
+ I K H K +S + + + ++ Y CN+C F
Sbjct: 429 QIIHTGEKPYKCGHCGKLFTSKSQLHVHKRIHTGEKP-------------YVCNKCGKAF 475
Query: 642 SNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQF 701
+N + TH K H + C +C + F + L+ H +H T Y C +C K F
Sbjct: 476 TNRSNLITHQKTHTGE--KSYICSKCGKAFTQRSDLITHQRIH--TGEKPYECNTCGKAF 531
Query: 702 SSVDDLQKHLLDMHTFVL-YHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFR 760
+ +L H +HT Y C C + F+ K + VH + H+ EK Y CT C F
Sbjct: 532 TQKSNLNIHQ-KIHTGERQYECHECGKAFNQKSILIVHQKI-HTGEKP-YVCTECGRAFI 588
Query: 761 KEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHITTHS--KKYNCKFCSKAFHA 818
++++ + H + K ++C CG++F+++ +L H H+ K Y C C KAF
Sbjct: 589 RKSNF---ITHQRIHTGEKPYECSDCGKSFTSKSQLLVHQPVHTGEKPYVCAECGKAFSG 645
Query: 819 IILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDD 878
L KH + T G P + Q S +
Sbjct: 646 RSNLSKHQK-------------THTGEKPYICSECGKTFRQ----------KSELITHHR 682
Query: 879 VDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRT 938
+ E Y C CG ++T + LQ H+ I GE + C C +
Sbjct: 683 IHTGEKPYECSDCGKSFTKKSQLQVHQ----RIHTGEKP------------YVCAECGKA 726
Query: 939 FFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHS 982
F + + L +H TH G K Y C ICG+ F + H+ +H+
Sbjct: 727 FSNRSNLNKHQTTHTGD-KPYKCGICGKGFVQKSVFSVHQSSHA 769
Score = 135 bits (339), Expect = 3e-31
Identities = 147/674 (21%), Positives = 244/674 (36%), Gaps = 142/674 (21%)
Query: 64 ESIYTCDHCQQDFESLADLTDH-------RAHRCPGDGDDDPQLSWVASSPS-------- 108
E +Y C C + F +DL+ H R H C G Q S +
Sbjct: 211 EKLYECSECGKGFPYNSDLSIHEKIHTGERHHECTDCGKAFTQKSTLKIHQKIHTGERSY 270
Query: 109 -----SKDVASPTQMIGDGCDLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDK 163
+ TQ+I + GE+ PY C C KSFI S L+ H+++H+
Sbjct: 271 ICIECGQAFIQKTQLIAHR-RIHSGEK------PYECNNCGKSFISKSQLQVHQRVHTRV 323
Query: 164 LPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFK 223
P+ CT ++F + + H K+ + +K C EC AF+ L IH + H+ KP++
Sbjct: 324 KPYICTEYGKVFSNNSNLITHEKIQSREKSSICTECGKAFTYRSELIIHQRIHTGEKPYE 383
Query: 224 CTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVL 283
C+ C R F+ S+L H + H K ++C C F + + H++
Sbjct: 384 CSDCGRAFTQKSALTVHQRIHTGEK-------------SYICMKCGLAFIR----KAHLI 426
Query: 284 TRHPQLSEKADLQCIHCPEVFVDENTLLAHIH-QAHANQK-HKCPMCPEQFSSVEGVYCH 341
T + + +C HC ++F ++ L H+H + H +K + C C + F++ + H
Sbjct: 427 THQIIHTGEKPYKCGHCGKLFTSKSQL--HVHKRIHTGEKPYVCNKCGKAFTNRSNLITH 484
Query: 342 LDSHRQPDSSNHSVSPDPVLGSVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDG 401
+H S + S + + +R T + KP
Sbjct: 485 QKTHTGEKS---------YICSKCGKAFTQRSDLITHQRIHTGE---KP----------- 521
Query: 402 QGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVR 461
Y C C K F + L IH K ++ + H C + L H +
Sbjct: 522 -------YECNTCGKA-FTQKSNLNIHQKIHTGERQYECHECGKAFNQKSILI---VH-Q 569
Query: 462 KLHKNHAYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQ 521
K+H + C C F ++ H R+ G + C+
Sbjct: 570 KIHTGE----------KPYVCTECGRAFIRKSNFITHQRI---------HTGEKPYECSD 610
Query: 522 CSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLT 581
C F ++S L H QP + + Y C C + F L+
Sbjct: 611 CGKSFTSKSQLLVH------------------QPVHTGEKPYVCAECGKA--FSGRSNLS 650
Query: 582 KHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKF 641
KH K + P S+ K + K + ++ Y C+ C F
Sbjct: 651 KHQKTHTGEKPYICSECGKTFRQ-----------KSELITHHRIHTGEKPYECSDCGKSF 699
Query: 642 SNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQF 701
+ Q H ++H + C +C + F ++ +L +H T H T Y C C K F
Sbjct: 700 TKKSQLQVHQRIHTG--EKPYVCAECGKAFSNRSNLNKHQTTH--TGDKPYKCGICGKGF 755
Query: 702 SSVDDLQKHLLDMH 715
+QK + +H
Sbjct: 756 -----VQKSVFSVH 764
Score = 128 bits (322), Expect = 3e-29
Identities = 153/630 (24%), Positives = 240/630 (38%), Gaps = 101/630 (16%)
Query: 408 VYSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNH 467
+Y C C K F + L IH K IH ++ H C C + L H +K+H
Sbjct: 213 LYECSECGK-GFPYNSDLSIHEK-IHTG--ERHHECTDCGKAFTQKSTLKIH-QKIHTGE 267
Query: 468 AYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFL 527
++ C C + F L H R+ G + CN C F+
Sbjct: 268 R----------SYICIECGQAFIQKTQLIAHRRIH---------SGEKPYECNNCGKSFI 308
Query: 528 TESSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVYSCPY-CTNSPIFGSILKLTKHIKE 586
++S L H Q+ H V PY CT +G +
Sbjct: 309 SKSQLQVH-QRVHTRVK---------------------PYICTE---YGKVFS------- 336
Query: 587 NHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSISNGE--YPCNQCDLKFSNF 644
N+ N+ + H K E+S + ++ + R L I GE Y C+ C F+
Sbjct: 337 NNSNL-ITHEKIQSREKSSICTECGKAFTYRSELIIHQR-IHTGEKPYECSDCGRAFTQK 394
Query: 645 ESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSV 704
+ H ++H + C +C F + L+ H +H T Y C C K F+S
Sbjct: 395 SALTVHQRIHTGE--KSYICMKCGLAFIRKAHLITHQIIH--TGEKPYKCGHCGKLFTSK 450
Query: 705 DDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEAD 764
L H Y C C + F ++ ++ H H+ EK Y C+ C F + +D
Sbjct: 451 SQLHVHKRIHTGEKPYVCNKCGKAFTNRSNLITHQKT-HTGEKS-YICSKCGKAFTQRSD 508
Query: 765 LQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCH--ITTHSKKYNCKFCSKAFH--AII 820
L + H + K ++C CG+ F+ + L H I T ++Y C C KAF+ +I+
Sbjct: 509 L---ITHQRIHTGEKPYECNTCGKAFTQKSNLNIHQKIHTGERQYECHECGKAFNQKSIL 565
Query: 821 LLEK--HLREKHCVFDAATENGTA-----NGVPPMATKKAE-PADLQGMLLKNPEAPNSH 872
++ + H EK V TE G A N + E P + S
Sbjct: 566 IVHQKIHTGEKPYV---CTECGRAFIRKSNFITHQRIHTGEKPYECSDC--GKSFTSKSQ 620
Query: 873 EASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPG--EDDGS--RKKAEFI-- 926
V E Y C CG A++ L H+ +P + G R+K+E I
Sbjct: 621 LLVHQPVHTGEKPYVCAECGKAFSGRSNLSKHQKTHTGEKPYICSECGKTFRQKSELITH 680
Query: 927 ------KGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVT 980
+ ++C+ C ++F ++ L+ H + H G K Y+C CG+ F + L +H+ T
Sbjct: 681 HRIHTGEKPYECSDCGKSFTKKSQLQVHQRIHTGE-KPYVCAECGKAFSNRSNLNKHQTT 739
Query: 981 HSKSLDTGTCRICKMPLQSEEEFIEHCQMH 1010
H+ C IC + F H H
Sbjct: 740 HTGD-KPYKCGICGKGFVQKSVFSVHQSSH 768
Score = 115 bits (289), Expect = 2e-25
Identities = 81/331 (24%), Positives = 141/331 (42%), Gaps = 42/331 (12%)
Query: 31 EPECDQKTSRALEDRNSVTSQEERNEDDEDMEDESIYTCDHCQQDFESLADLTDH-RAHR 89
+P K +A +R+++ + ++ + ++ Y C C + F +DL H R H
Sbjct: 464 KPYVCNKCGKAFTNRSNLITHQKTHTGEKS------YICSKCGKAFTQRSDLITHQRIHT 517
Query: 90 CPGDGDDDPQLSWVASSPSSKDVASPTQMIGDGCDLGLGEEEGGTGLPYPCQFCDKSFIR 149
G+ + + + + K + Q I G E + Y C C K+F +
Sbjct: 518 ----GEKPYECNTCGKAFTQKSNLNIHQKIHTG------ERQ------YECHECGKAFNQ 561
Query: 150 LSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHL 209
S L H++IH+ + P+ CT C R F K + H ++HTG+K Y C +C +F+ L
Sbjct: 562 KSILIVHQKIHTGEKPYVCTECGRAFIRKSNFITHQRIHTGEKPYECSDCGKSFTSKSQL 621
Query: 210 KIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLA---------KSEK---- 256
+H H+ KP+ C C + FS S+L H + H K ++ KSE
Sbjct: 622 LVHQPVHTGEKPYVCAECGKAFSGRSNLSKHQKTHTGEKPYICSECGKTFRQKSELITHH 681
Query: 257 --EAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHI 314
+ + C C +F++ +L+ H + EK + C C + F + + L H
Sbjct: 682 RIHTGEKPYECSDCGKSFTKKSQLQVH---QRIHTGEKPYV-CAECGKAFSNRSNLNKHQ 737
Query: 315 HQAHANQKHKCPMCPEQFSSVEGVYCHLDSH 345
++ +KC +C + F H SH
Sbjct: 738 TTHTGDKPYKCGICGKGFVQKSVFSVHQSSH 768
Score = 114 bits (285), Expect = 6e-25
Identities = 91/406 (22%), Positives = 163/406 (40%), Gaps = 76/406 (18%)
Query: 137 PYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 196
PY C C K F S L H++IH+ + P+ C C + F ++ + H K HTG+K Y C
Sbjct: 437 PYKCGHCGKLFTSKSQLHVHKRIHTGEKPYVCNKCGKAFTNRSNLITHQKTHTGEKSYIC 496
Query: 197 HECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEK 256
+C AF++ L H + H+ KP++C C + F+ S+L H + H ++
Sbjct: 497 SKCGKAFTQRSDLITHQRIHTGEKPYECNTCGKAFTQKSNLNIHQKIHTGERQ------- 549
Query: 257 EAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQL-SEKADLQCIHCPEVFVDENTLLAHIH 315
+ C C F+Q K +L H ++ + + C C F+ ++ + H
Sbjct: 550 ------YECHECGKAFNQ-----KSILIVHQKIHTGEKPYVCTECGRAFIRKSNFITH-Q 597
Query: 316 QAHANQK-HKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDS 374
+ H +K ++C C + F+S + H H P + + + + +
Sbjct: 598 RIHTGEKPYECSDCGKSFTSKSQLLVHQPVH---------TGEKPYVCAECGKAFSGRSN 648
Query: 375 SASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHA 434
+ ++ T + KP Y C C K F + L H +
Sbjct: 649 LSKHQKTHTGE---KP------------------YICSECGK-TFRQKSELITHHRIHTG 686
Query: 435 DKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINS 494
+KP + C C S L H +++H + C C + F++ ++
Sbjct: 687 EKP---YECSDCGKSFTKKSQLQVH-QRIHTGE----------KPYVCAECGKAFSNRSN 732
Query: 495 LQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAH 540
L +H + +H G+ + C C GF+ +S + H Q +H
Sbjct: 733 LNKH-QTTH--------TGDKPYKCGICGKGFVQKSVFSVH-QSSH 768
Score = 104 bits (260), Expect = 5e-22
Identities = 55/183 (30%), Positives = 82/183 (44%), Gaps = 18/183 (9%)
Query: 137 PYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 196
PY C C KSF S L H+ +H+ + P+ C C + F + + +H K HTG+K Y C
Sbjct: 605 PYECSDCGKSFTSKSQLLVHQPVHTGEKPYVCAECGKAFSGRSNLSKHQKTHTGEKPYIC 664
Query: 197 HECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEK 256
EC F + L H + H+ KP++C+ C + F+ S LQ H + H K
Sbjct: 665 SECGKTFRQKSELITHHRIHTGEKPYECSDCGKSFTKKSQLQVHQRIHTGEK-------- 716
Query: 257 EAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQ 316
++C C FS L KH T + +C C + FV ++ H
Sbjct: 717 -----PYVCAECGKAFSNRSNLNKHQTTH----TGDKPYKCGICGKGFVQKSVFSVH-QS 766
Query: 317 AHA 319
+HA
Sbjct: 767 SHA 769
Score = 87.4 bits (215), Expect = 8e-17
Identities = 98/410 (23%), Positives = 151/410 (36%), Gaps = 59/410 (14%)
Query: 879 VDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRT 938
V E +Y C CG A+ + H+ +P KCN C ++
Sbjct: 151 VPTGEKLYVCIECGRAFVQKPEFITHQKTHMREKPP----------------KCNECGKS 194
Query: 939 FFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQ 998
FF + L H + H G K Y C CG+ FP L+ H+ H+ C C
Sbjct: 195 FFQVSSLFRHHRIHTG-EKLYECSECGKGFPYNSDLSIHEKIHTGERH-HECTDCGKAFT 252
Query: 999 SEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQ 1058
+ H ++H R+ + C+ C Q +L H H
Sbjct: 253 QKSTLKIHQKIHTGERS----YICIECGQAFIQKTQLIAHRRIHSG-------------- 294
Query: 1059 GLQKLYKCALCLKEFRSKQDL---VKLDVNGLPYGLCAGCMARSANGQVGGLAPPEPADR 1115
+K Y+C C K F SK L ++ PY +C +N L E
Sbjct: 295 --EKPYECNNCGKSFISKSQLQVHQRVHTRVKPY-ICTEYGKVFSNN--SNLITHEKIQS 349
Query: 1116 PCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSG-PRKGTQTSPV-------PRKKT 1167
C EC F +L H ++ + E S R TQ S + +K+
Sbjct: 350 REKSSICTECGKAFTYRSELIIHQRIHTGEKPYECSDCGRAFTQKSALTVHQRIHTGEKS 409
Query: 1168 YQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGMGG 1227
Y C+KC + F + + H H E+ ++C C ++F S ++L H H+ E
Sbjct: 410 YICMKCGLAFIRKAHLITHQIIHTGEK--PYKCGHCGKLFTSKSQLHVHKRIHTGE---K 464
Query: 1228 TFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNH 1277
+ C C F + L H G +K Y CS+C + F +++L H
Sbjct: 465 PYVCNKCGKAFTNRSNLITHQKTHTG--EKSYICSKCGKAFTQRSDLITH 512
>gi|40217792 zinc finger protein 585A [Homo sapiens]
Length = 714
Score = 194 bits (494), Expect = 3e-49
Identities = 172/682 (25%), Positives = 253/682 (37%), Gaps = 143/682 (20%)
Query: 138 YPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCH 197
Y C C K F S L HE+IH+ + +CT C + F K + H K+HTG++ Y C
Sbjct: 159 YECSQCGKGFSYNSDLSIHEKIHTGERHHECTDCGKAFTQKSTLKMHQKIHTGERSYICI 218
Query: 198 ECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEKE 257
EC AF + HL H + H+ KP++C+ C + F S S LQ H + H + K
Sbjct: 219 ECGQAFIQKTHLIAHRRIHTGEKPYECSNCGKSFISKSQLQVHQRVHTRVK--------- 269
Query: 258 AKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQA 317
++C FS L H + Q EK+ + C C + F + L+ H +
Sbjct: 270 ----PYICTEYGKVFSNNSNLVTH---KKVQSREKSSI-CTECGKAFTYRSELIIH-QRI 320
Query: 318 HANQK-HKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDSSA 376
H +K ++C C + F+ + H H S + +A + A +
Sbjct: 321 HTGEKPYECSDCGKAFTQKSALTVHQRIH------TGEKSYICMKCGLAFIQKAHLIAHQ 374
Query: 377 SVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHADK 436
+ G P + C +C K F S + L +H + +K
Sbjct: 375 IIHTGEKP------------------------HKCGHCGKL-FTSKSQLHVHKRIHTGEK 409
Query: 437 PQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINSLQ 496
P + C C + NL H +K H ++ C+ C + F + L
Sbjct: 410 P---YMCNKCGKAFTNRSNLITH-QKTHTGE----------KSYICSKCGKAFTQRSDLI 455
Query: 497 EHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPT 556
H R+ G + CN C F +S L H Q
Sbjct: 456 THQRI---------HTGEKPYECNTCGKAFTQKSHLNIH------------------QKI 488
Query: 557 QSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPK 616
+ Y C C + N K+I + H K E+ V
Sbjct: 489 HTGERQYECHECGKA--------------FNQKSILIVHQKIHTGEKPYV---------- 524
Query: 617 RQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQES 676
C +C F +F TH ++H + C C + F S+
Sbjct: 525 -----------------CTECGRAFIRKSNFITHQRIHTG--EKPYECSDCGKSFTSKSQ 565
Query: 677 LLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQ 736
LL H VH T YVC C K FS +L KH Y C+ C + F K +
Sbjct: 566 LLVHQPVH--TGEKPYVCAECGKAFSGRSNLSKHQKTHTGEKPYICSECGKTFRQKSELI 623
Query: 737 VHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVEL 796
H + H+ EK Y C+ C F K++ LQVH + H G K + C CG+ F+ L
Sbjct: 624 THHRI-HTGEKP-YECSDCGKSFTKKSQLQVH-QRIHTGE--KPYVCAECGKAFTDRSNL 678
Query: 797 QCHITTHS--KKYNCKFCSKAF 816
H TTH+ K Y C C K F
Sbjct: 679 NKHQTTHTGDKPYKCGICGKGF 700
Score = 164 bits (414), Expect = 7e-40
Identities = 184/815 (22%), Positives = 291/815 (35%), Gaps = 155/815 (19%)
Query: 171 CSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRG 230
C ++ +K+ + K++ G+K Y C + E F++ LK+HLK + K + C C +
Sbjct: 52 CRKILSYKQVSSQPQKMYPGEKAYECAKFEKIFTQKSQLKVHLKVLAGEKLYVCIECGKA 111
Query: 231 FSSTSSLQSHMQAHKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLS 290
F H + H + K F C+ C +F Q L +H +
Sbjct: 112 FVQKPEFIIHQKTHMREKP-------------FKCNECGKSFFQVSSLFRH---QRIHTG 155
Query: 291 EKADLQCIHCPEVFVDENTLLAHIHQAHANQKHKCPMCPEQFSSVEGVYCHLDSHRQPDS 350
EK +C C + F + L H + H+C C + F+ + H H S
Sbjct: 156 EKL-YECSQCGKGFSYNSDLSIHEKIHTGERHHECTDCGKAFTQKSTLKMHQKIHTGERS 214
Query: 351 SNHSVSPDPVLGSVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYS 410
+ A + + + G P Y
Sbjct: 215 YIC------IECGQAFIQKTHLIAHRRIHTGEKP------------------------YE 244
Query: 411 CPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYP 470
C C K F S + L++H + KP IC + N + V HK
Sbjct: 245 CSNCGK-SFISKSQLQVHQRVHTRVKPY------ICTEYGKVFSNNSNLVT--HKK---- 291
Query: 471 VMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTES 530
+Q S+ C C + F + L H R+ G + C+ C F +S
Sbjct: 292 -VQSREKSSI-CTECGKAFTYRSELIIHQRIH---------TGEKPYECSDCGKAFTQKS 340
Query: 531 SLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKN 590
+LT H Q+ H S Y C C + I + L + I K
Sbjct: 341 ALTVH-QRIHTGEKS-----------------YICMKCGLAFIQKAHLIAHQIIHTGEKP 382
Query: 591 IPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTH 650
H K +S + + + ++ Y CN+C F+N + TH
Sbjct: 383 HKCGHCGKLFTSKSQLHVHKRIHTGEKP-------------YMCNKCGKAFTNRSNLITH 429
Query: 651 LKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKH 710
K H + C +C + F + L+ H +H T Y C +C K F+ L H
Sbjct: 430 QKTHTGE--KSYICSKCGKAFTQRSDLITHQRIH--TGEKPYECNTCGKAFTQKSHLNIH 485
Query: 711 LLDMHTFVL-YHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHV 769
+HT Y C C + F+ K + VH + H+ EK Y CT C F ++++ +
Sbjct: 486 Q-KIHTGERQYECHECGKAFNQKSILIVHQKI-HTGEKP-YVCTECGRAFIRKSNF---I 539
Query: 770 KHSHLGNPAKAHKCIFCGETFSTEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHLR 827
H + K ++C CG++F+++ +L H H+ K Y C C KAF L KH +
Sbjct: 540 THQRIHTGEKPYECSDCGKSFTSKSQLLVHQPVHTGEKPYVCAECGKAFSGRSNLSKHQK 599
Query: 828 EKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYG 887
T G P + Q S + + E Y
Sbjct: 600 -------------THTGEKPYICSECGKTFRQ----------KSELITHHRIHTGEKPYE 636
Query: 888 CDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLRE 947
C CG ++T + LQ H+ I GE + C C + F + L +
Sbjct: 637 CSDCGKSFTKKSQLQVHQ----RIHTGEKP------------YVCAECGKAFTDRSNLNK 680
Query: 948 HLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHS 982
H TH G K Y C ICG+ F + H+ +H+
Sbjct: 681 HQTTHTGD-KPYKCGICGKGFVQKSVFSVHQSSHA 714
Score = 156 bits (394), Expect = 1e-37
Identities = 168/693 (24%), Positives = 267/693 (38%), Gaps = 103/693 (14%)
Query: 618 QRLSASANSISNGE--YPCNQCDLKFSNFESFQTHLKLHLELLLRKQ--ACPQCKEDFDS 673
+++S+ + GE Y C KF + ++ LK+HL++L ++ C +C + F
Sbjct: 59 KQVSSQPQKMYPGEKAYEC----AKFEKIFTQKSQLKVHLKVLAGEKLYVCIECGKAFVQ 114
Query: 674 QESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKV 733
+ + H H + C C K F V L +H LY C+ C + F
Sbjct: 115 KPEFIIHQKTHMREKP--FKCNECGKSFFQVSSLFRHQRIHTGEKLYECSQCGKGFSYNS 172
Query: 734 SIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTE 793
+ +H + H+ E+ + CT C F +++ L++H K H G +++ CI CG+ F +
Sbjct: 173 DLSIHEKI-HTGERH-HECTDCGKAFTQKSTLKMHQK-IHTGE--RSYICIECGQAFIQK 227
Query: 794 VELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFD-AATENGT--ANGVPPM 848
L H I T K Y C C K+F + L+ H R V TE G +N +
Sbjct: 228 THLIAHRRIHTGEKPYECSNCGKSFISKSQLQVHQRVHTRVKPYICTEYGKVFSNNSNLV 287
Query: 849 ATKKAEPADLQGMLLKNPEA--PNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRL 906
KK + + + + +A S + E Y C CG A+T + L H+
Sbjct: 288 THKKVQSREKSSICTECGKAFTYRSELIIHQRIHTGEKPYECSDCGKAFTQKSALTVHQ- 346
Query: 907 RDHNIRPGEDD--------GSRKKAEFI--------KGSHKCNVCSRTFFSENGLREHLQ 950
I GE +KA I + HKC C + F S++ L H +
Sbjct: 347 ---RIHTGEKSYICMKCGLAFIQKAHLIAHQIIHTGEKPHKCGHCGKLFTSKSQLHVHKR 403
Query: 951 THRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMH 1010
H G K YMC CG+ F + L H+ TH+ + C C + I H ++H
Sbjct: 404 IHTGE-KPYMCNKCGKAFTNRSNLITHQKTHTGE-KSYICSKCGKAFTQRSDLITHQRIH 461
Query: 1011 PDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCL 1070
+ + C C + T L IH H ++ Y+C C
Sbjct: 462 TGEKP----YECNTCGKAFTQKSHLNIHQKIHTG----------------ERQYECHECG 501
Query: 1071 KEFRSKQDLV---KLDVNGLPYGLCAGC---MARSANGQVGGLAPPEPADRPCAGLRCPE 1124
K F K L+ K+ PY +C C R +N ++P C +
Sbjct: 502 KAFNQKSILIVHQKIHTGEKPY-VCTECGRAFIRKSNFITHQRI--HTGEKP---YECSD 555
Query: 1125 CSVKFESAEDLESHMQVDHRDLTPETSGPRKGTQTSPVPRKKTYQCIKCQMTFENEREIQ 1184
C F S L H V + K Y C +C F +
Sbjct: 556 CGKSFTSKSQLLVHQPVHTGE--------------------KPYVCAECGKAFSGRSNLS 595
Query: 1185 IHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKL 1244
H H E+ + C C + F ++L+ H H+ E ++C C F + ++L
Sbjct: 596 KHQKTHTGEKP--YICSECGKTFRQKSELITHHRIHTGEK---PYECSDCGKSFTKKSQL 650
Query: 1245 QQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNH 1277
Q H +H E K Y C++C + F ++ L H
Sbjct: 651 QVHQ-RIHTGE-KPYVCAECGKAFTDRSNLNKH 681
Score = 146 bits (369), Expect = 1e-34
Identities = 163/707 (23%), Positives = 261/707 (36%), Gaps = 142/707 (20%)
Query: 414 CSKRD--FNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHV--RKLHKNHAY 469
C+K + F + L++HLK + +K +C++ E + +K H
Sbjct: 77 CAKFEKIFTQKSQLKVHLKVLAGEK------LYVCIECGKAFVQKPEFIIHQKTHMRE-- 128
Query: 470 PVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTE 529
F CN C + F ++SL H R+ G + C+QC GF
Sbjct: 129 --------KPFKCNECGKSFFQVSSLFRHQRIH---------TGEKLYECSQCGKGFSYN 171
Query: 530 SSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHK 589
S L+ H + + + C C + S LK+
Sbjct: 172 SDLSIH------------------EKIHTGERHHECTDCGKAFTQKSTLKM--------- 204
Query: 590 NIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSISNGE--YPCNQCDLKFSNFESF 647
H K E+S + + + ++ L A I GE Y C+ C F +
Sbjct: 205 -----HQKIHTGERSYICIECGQAFIQKTHLIAHRR-IHTGEKPYECSNCGKSFISKSQL 258
Query: 648 QTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDL 707
Q H ++H + + C + + F + +L+ H V S+ +C C K F+ +L
Sbjct: 259 QVHQRVHTRV--KPYICTEYGKVFSNNSNLVTHKKVQSREKSS--ICTECGKAFTYRSEL 314
Query: 708 QKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQV 767
H Y C+ C + F K ++ VH + H+ EK Y C C F ++A L
Sbjct: 315 IIHQRIHTGEKPYECSDCGKAFTQKSALTVHQRI-HTGEKS-YICMKCGLAFIQKAHL-- 370
Query: 768 HVKHSHLGNPAKAHKCIFCGETFSTEVELQCH--ITTHSKKYNCKFCSKAF----HAIIL 821
+ H + K HKC CG+ F+++ +L H I T K Y C C KAF + I
Sbjct: 371 -IAHQIIHTGEKPHKCGHCGKLFTSKSQLHVHKRIHTGEKPYMCNKCGKAFTNRSNLITH 429
Query: 822 LEKHLREKHCV-----------FDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAPN 870
+ H EK + D T G P A Q
Sbjct: 430 QKTHTGEKSYICSKCGKAFTQRSDLITHQRIHTGEKPYECNTCGKAFTQ----------K 479
Query: 871 SHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDD--------GSRKK 922
SH + E Y C CG A+ + +L H+ I GE +K
Sbjct: 480 SHLNIHQKIHTGERQYECHECGKAFNQKSILIVHQ----KIHTGEKPYVCTECGRAFIRK 535
Query: 923 AEFI--------KGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTL 974
+ FI + ++C+ C ++F S++ L H H G K Y+C CG+ F L
Sbjct: 536 SNFITHQRIHTGEKPYECSDCGKSFTSKSQLLVHQPVHTG-EKPYVCAECGKAFSGRSNL 594
Query: 975 TEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLE 1034
++H+ TH+ C C + + E I H ++H + + C C ++ T +
Sbjct: 595 SKHQKTHTGE-KPYICSECGKTFRQKSELITHHRIHTGEK----PYECSDCGKSFTKKSQ 649
Query: 1035 LKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLVK 1081
L++H H +K Y CA C K F + +L K
Sbjct: 650 LQVHQRIHTG----------------EKPYVCAECGKAFTDRSNLNK 680
Score = 134 bits (337), Expect = 6e-31
Identities = 148/669 (22%), Positives = 237/669 (35%), Gaps = 132/669 (19%)
Query: 64 ESIYTCDHCQQDFESLADLTDH-------RAHRCPGDGDDDPQLSWVASSPSSKDVASPT 116
E +Y C C + F +DL+ H R H C G Q S + K
Sbjct: 156 EKLYECSQCGKGFSYNSDLSIHEKIHTGERHHECTDCGKAFTQKSTLKMH--QKIHTGER 213
Query: 117 QMIGDGCDLG-------LGEEEGGTG-LPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKC 168
I C + TG PY C C KSFI S L+ H+++H+ P+ C
Sbjct: 214 SYICIECGQAFIQKTHLIAHRRIHTGEKPYECSNCGKSFISKSQLQVHQRVHTRVKPYIC 273
Query: 169 TYCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCK 228
T ++F + + H K+ + +K C EC AF+ L IH + H+ KP++C+ C
Sbjct: 274 TEYGKVFSNNSNLVTHKKVQSREKSSICTECGKAFTYRSELIIHQRIHTGEKPYECSDCG 333
Query: 229 RGFSSTSSLQSHMQAHKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQ 288
+ F+ S+L H + H K ++C C F Q L H + +
Sbjct: 334 KAFTQKSALTVHQRIHTGEK-------------SYICMKCGLAFIQKAHLIAHQIIHTGE 380
Query: 289 LSEKADLQCIHCPEVFVDENTLLAHIH-QAHANQK-HKCPMCPEQFSSVEGVYCHLDSHR 346
K C HC ++F ++ L H+H + H +K + C C + F++ + H +H
Sbjct: 381 KPHK----CGHCGKLFTSKSQL--HVHKRIHTGEKPYMCNKCGKAFTNRSNLITHQKTHT 434
Query: 347 QPDSSNHSVSPDPVLGSVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTK 406
S + S + + +R T + KP
Sbjct: 435 GEKS---------YICSKCGKAFTQRSDLITHQRIHTGE---KP---------------- 466
Query: 407 VVYSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKN 466
Y C C K F + L IH K ++ + H C + L H +K+H
Sbjct: 467 --YECNTCGKA-FTQKSHLNIHQKIHTGERQYECHECGKAFNQKSILI---VH-QKIHTG 519
Query: 467 HAYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGF 526
+ C C F ++ H R+ G + C+ C F
Sbjct: 520 E----------KPYVCTECGRAFIRKSNFITHQRI---------HTGEKPYECSDCGKSF 560
Query: 527 LTESSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKE 586
++S L H QP + + Y C C + F L+KH K
Sbjct: 561 TSKSQLLVH------------------QPVHTGEKPYVCAECGKA--FSGRSNLSKHQKT 600
Query: 587 NHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFES 646
+ P S+ K + K + ++ Y C+ C F+
Sbjct: 601 HTGEKPYICSECGKTFRQ-----------KSELITHHRIHTGEKPYECSDCGKSFTKKSQ 649
Query: 647 FQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDD 706
Q H ++H + C +C + F + +L +H T H T Y C C K F
Sbjct: 650 LQVHQRIHTG--EKPYVCAECGKAFTDRSNLNKHQTTH--TGDKPYKCGICGKGF----- 700
Query: 707 LQKHLLDMH 715
+QK + +H
Sbjct: 701 VQKSVFSVH 709
Score = 126 bits (316), Expect = 2e-28
Identities = 151/630 (23%), Positives = 240/630 (38%), Gaps = 101/630 (16%)
Query: 408 VYSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNH 467
+Y C C K F+ + L IH K IH ++ H C C + L H +K+H
Sbjct: 158 LYECSQCGK-GFSYNSDLSIHEK-IHTG--ERHHECTDCGKAFTQKSTLKMH-QKIHTGE 212
Query: 468 AYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFL 527
++ C C + F L H R+ G + C+ C F+
Sbjct: 213 R----------SYICIECGQAFIQKTHLIAHRRIH---------TGEKPYECSNCGKSFI 253
Query: 528 TESSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVYSCPY-CTNSPIFGSILKLTKHIKE 586
++S L H Q+ H V PY CT +G +
Sbjct: 254 SKSQLQVH-QRVHTRVK---------------------PYICTE---YGKVFS------- 281
Query: 587 NHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSISNGE--YPCNQCDLKFSNF 644
N+ N+ + H K E+S + ++ + R L I GE Y C+ C F+
Sbjct: 282 NNSNL-VTHKKVQSREKSSICTECGKAFTYRSELIIHQR-IHTGEKPYECSDCGKAFTQK 339
Query: 645 ESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSV 704
+ H ++H + C +C F + L+ H +H T + C C K F+S
Sbjct: 340 SALTVHQRIHTGE--KSYICMKCGLAFIQKAHLIAHQIIH--TGEKPHKCGHCGKLFTSK 395
Query: 705 DDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEAD 764
L H Y C C + F ++ ++ H H+ EK Y C+ C F + +D
Sbjct: 396 SQLHVHKRIHTGEKPYMCNKCGKAFTNRSNLITHQKT-HTGEKS-YICSKCGKAFTQRSD 453
Query: 765 LQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCH--ITTHSKKYNCKFCSKAFH--AII 820
L + H + K ++C CG+ F+ + L H I T ++Y C C KAF+ +I+
Sbjct: 454 L---ITHQRIHTGEKPYECNTCGKAFTQKSHLNIHQKIHTGERQYECHECGKAFNQKSIL 510
Query: 821 LLEK--HLREKHCVFDAATENGTA-----NGVPPMATKKAE-PADLQGMLLKNPEAPNSH 872
++ + H EK V TE G A N + E P + S
Sbjct: 511 IVHQKIHTGEKPYV---CTECGRAFIRKSNFITHQRIHTGEKPYECSDC--GKSFTSKSQ 565
Query: 873 EASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPG--EDDGS--RKKAEFI-- 926
V E Y C CG A++ L H+ +P + G R+K+E I
Sbjct: 566 LLVHQPVHTGEKPYVCAECGKAFSGRSNLSKHQKTHTGEKPYICSECGKTFRQKSELITH 625
Query: 927 ------KGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVT 980
+ ++C+ C ++F ++ L+ H + H G K Y+C CG+ F L +H+ T
Sbjct: 626 HRIHTGEKPYECSDCGKSFTKKSQLQVHQRIHTGE-KPYVCAECGKAFTDRSNLNKHQTT 684
Query: 981 HSKSLDTGTCRICKMPLQSEEEFIEHCQMH 1010
H+ C IC + F H H
Sbjct: 685 HTGD-KPYKCGICGKGFVQKSVFSVHQSSH 713
Score = 118 bits (296), Expect = 3e-26
Identities = 82/331 (24%), Positives = 141/331 (42%), Gaps = 42/331 (12%)
Query: 31 EPECDQKTSRALEDRNSVTSQEERNEDDEDMEDESIYTCDHCQQDFESLADLTDH-RAHR 89
+P K +A +R+++ + ++ + ++ Y C C + F +DL H R H
Sbjct: 409 KPYMCNKCGKAFTNRSNLITHQKTHTGEKS------YICSKCGKAFTQRSDLITHQRIHT 462
Query: 90 CPGDGDDDPQLSWVASSPSSKDVASPTQMIGDGCDLGLGEEEGGTGLPYPCQFCDKSFIR 149
G+ + + + + K + Q I G E + Y C C K+F +
Sbjct: 463 ----GEKPYECNTCGKAFTQKSHLNIHQKIHTG------ERQ------YECHECGKAFNQ 506
Query: 150 LSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHL 209
S L H++IH+ + P+ CT C R F K + H ++HTG+K Y C +C +F+ L
Sbjct: 507 KSILIVHQKIHTGEKPYVCTECGRAFIRKSNFITHQRIHTGEKPYECSDCGKSFTSKSQL 566
Query: 210 KIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLA---------KSEK---- 256
+H H+ KP+ C C + FS S+L H + H K ++ KSE
Sbjct: 567 LVHQPVHTGEKPYVCAECGKAFSGRSNLSKHQKTHTGEKPYICSECGKTFRQKSELITHH 626
Query: 257 --EAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHI 314
+ + C C +F++ +L+ H + EK + C C + F D + L H
Sbjct: 627 RIHTGEKPYECSDCGKSFTKKSQLQVH---QRIHTGEKPYV-CAECGKAFTDRSNLNKHQ 682
Query: 315 HQAHANQKHKCPMCPEQFSSVEGVYCHLDSH 345
++ +KC +C + F H SH
Sbjct: 683 TTHTGDKPYKCGICGKGFVQKSVFSVHQSSH 713
Score = 103 bits (257), Expect = 1e-21
Identities = 54/183 (29%), Positives = 82/183 (44%), Gaps = 18/183 (9%)
Query: 137 PYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 196
PY C C KSF S L H+ +H+ + P+ C C + F + + +H K HTG+K Y C
Sbjct: 550 PYECSDCGKSFTSKSQLLVHQPVHTGEKPYVCAECGKAFSGRSNLSKHQKTHTGEKPYIC 609
Query: 197 HECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEK 256
EC F + L H + H+ KP++C+ C + F+ S LQ H + H K
Sbjct: 610 SECGKTFRQKSELITHHRIHTGEKPYECSDCGKSFTKKSQLQVHQRIHTGEK-------- 661
Query: 257 EAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQ 316
++C C F+ L KH T + +C C + FV ++ H
Sbjct: 662 -----PYVCAECGKAFTDRSNLNKHQTTH----TGDKPYKCGICGKGFVQKSVFSVH-QS 711
Query: 317 AHA 319
+HA
Sbjct: 712 SHA 714
>gi|22749331 zinc finger protein 585A [Homo sapiens]
Length = 714
Score = 194 bits (494), Expect = 3e-49
Identities = 172/682 (25%), Positives = 253/682 (37%), Gaps = 143/682 (20%)
Query: 138 YPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCH 197
Y C C K F S L HE+IH+ + +CT C + F K + H K+HTG++ Y C
Sbjct: 159 YECSQCGKGFSYNSDLSIHEKIHTGERHHECTDCGKAFTQKSTLKMHQKIHTGERSYICI 218
Query: 198 ECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEKE 257
EC AF + HL H + H+ KP++C+ C + F S S LQ H + H + K
Sbjct: 219 ECGQAFIQKTHLIAHRRIHTGEKPYECSNCGKSFISKSQLQVHQRVHTRVK--------- 269
Query: 258 AKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQA 317
++C FS L H + Q EK+ + C C + F + L+ H +
Sbjct: 270 ----PYICTEYGKVFSNNSNLVTH---KKVQSREKSSI-CTECGKAFTYRSELIIH-QRI 320
Query: 318 HANQK-HKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDSSA 376
H +K ++C C + F+ + H H S + +A + A +
Sbjct: 321 HTGEKPYECSDCGKAFTQKSALTVHQRIH------TGEKSYICMKCGLAFIQKAHLIAHQ 374
Query: 377 SVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHADK 436
+ G P + C +C K F S + L +H + +K
Sbjct: 375 IIHTGEKP------------------------HKCGHCGKL-FTSKSQLHVHKRIHTGEK 409
Query: 437 PQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINSLQ 496
P + C C + NL H +K H ++ C+ C + F + L
Sbjct: 410 P---YMCNKCGKAFTNRSNLITH-QKTHTGE----------KSYICSKCGKAFTQRSDLI 455
Query: 497 EHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPT 556
H R+ G + CN C F +S L H Q
Sbjct: 456 THQRI---------HTGEKPYECNTCGKAFTQKSHLNIH------------------QKI 488
Query: 557 QSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPK 616
+ Y C C + N K+I + H K E+ V
Sbjct: 489 HTGERQYECHECGKA--------------FNQKSILIVHQKIHTGEKPYV---------- 524
Query: 617 RQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQES 676
C +C F +F TH ++H + C C + F S+
Sbjct: 525 -----------------CTECGRAFIRKSNFITHQRIHTG--EKPYECSDCGKSFTSKSQ 565
Query: 677 LLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQ 736
LL H VH T YVC C K FS +L KH Y C+ C + F K +
Sbjct: 566 LLVHQPVH--TGEKPYVCAECGKAFSGRSNLSKHQKTHTGEKPYICSECGKTFRQKSELI 623
Query: 737 VHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVEL 796
H + H+ EK Y C+ C F K++ LQVH + H G K + C CG+ F+ L
Sbjct: 624 THHRI-HTGEKP-YECSDCGKSFTKKSQLQVH-QRIHTGE--KPYVCAECGKAFTDRSNL 678
Query: 797 QCHITTHS--KKYNCKFCSKAF 816
H TTH+ K Y C C K F
Sbjct: 679 NKHQTTHTGDKPYKCGICGKGF 700
Score = 164 bits (414), Expect = 7e-40
Identities = 184/815 (22%), Positives = 291/815 (35%), Gaps = 155/815 (19%)
Query: 171 CSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRG 230
C ++ +K+ + K++ G+K Y C + E F++ LK+HLK + K + C C +
Sbjct: 52 CRKILSYKQVSSQPQKMYPGEKAYECAKFEKIFTQKSQLKVHLKVLAGEKLYVCIECGKA 111
Query: 231 FSSTSSLQSHMQAHKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLS 290
F H + H + K F C+ C +F Q L +H +
Sbjct: 112 FVQKPEFIIHQKTHMREKP-------------FKCNECGKSFFQVSSLFRH---QRIHTG 155
Query: 291 EKADLQCIHCPEVFVDENTLLAHIHQAHANQKHKCPMCPEQFSSVEGVYCHLDSHRQPDS 350
EK +C C + F + L H + H+C C + F+ + H H S
Sbjct: 156 EKL-YECSQCGKGFSYNSDLSIHEKIHTGERHHECTDCGKAFTQKSTLKMHQKIHTGERS 214
Query: 351 SNHSVSPDPVLGSVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYS 410
+ A + + + G P Y
Sbjct: 215 YIC------IECGQAFIQKTHLIAHRRIHTGEKP------------------------YE 244
Query: 411 CPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYP 470
C C K F S + L++H + KP IC + N + V HK
Sbjct: 245 CSNCGK-SFISKSQLQVHQRVHTRVKPY------ICTEYGKVFSNNSNLVT--HKK---- 291
Query: 471 VMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTES 530
+Q S+ C C + F + L H R+ G + C+ C F +S
Sbjct: 292 -VQSREKSSI-CTECGKAFTYRSELIIHQRIH---------TGEKPYECSDCGKAFTQKS 340
Query: 531 SLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKN 590
+LT H Q+ H S Y C C + I + L + I K
Sbjct: 341 ALTVH-QRIHTGEKS-----------------YICMKCGLAFIQKAHLIAHQIIHTGEKP 382
Query: 591 IPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTH 650
H K +S + + + ++ Y CN+C F+N + TH
Sbjct: 383 HKCGHCGKLFTSKSQLHVHKRIHTGEKP-------------YMCNKCGKAFTNRSNLITH 429
Query: 651 LKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKH 710
K H + C +C + F + L+ H +H T Y C +C K F+ L H
Sbjct: 430 QKTHTGE--KSYICSKCGKAFTQRSDLITHQRIH--TGEKPYECNTCGKAFTQKSHLNIH 485
Query: 711 LLDMHTFVL-YHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHV 769
+HT Y C C + F+ K + VH + H+ EK Y CT C F ++++ +
Sbjct: 486 Q-KIHTGERQYECHECGKAFNQKSILIVHQKI-HTGEKP-YVCTECGRAFIRKSNF---I 539
Query: 770 KHSHLGNPAKAHKCIFCGETFSTEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHLR 827
H + K ++C CG++F+++ +L H H+ K Y C C KAF L KH +
Sbjct: 540 THQRIHTGEKPYECSDCGKSFTSKSQLLVHQPVHTGEKPYVCAECGKAFSGRSNLSKHQK 599
Query: 828 EKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYG 887
T G P + Q S + + E Y
Sbjct: 600 -------------THTGEKPYICSECGKTFRQ----------KSELITHHRIHTGEKPYE 636
Query: 888 CDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLRE 947
C CG ++T + LQ H+ I GE + C C + F + L +
Sbjct: 637 CSDCGKSFTKKSQLQVHQ----RIHTGEKP------------YVCAECGKAFTDRSNLNK 680
Query: 948 HLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHS 982
H TH G K Y C ICG+ F + H+ +H+
Sbjct: 681 HQTTHTGD-KPYKCGICGKGFVQKSVFSVHQSSHA 714
Score = 156 bits (394), Expect = 1e-37
Identities = 168/693 (24%), Positives = 267/693 (38%), Gaps = 103/693 (14%)
Query: 618 QRLSASANSISNGE--YPCNQCDLKFSNFESFQTHLKLHLELLLRKQ--ACPQCKEDFDS 673
+++S+ + GE Y C KF + ++ LK+HL++L ++ C +C + F
Sbjct: 59 KQVSSQPQKMYPGEKAYEC----AKFEKIFTQKSQLKVHLKVLAGEKLYVCIECGKAFVQ 114
Query: 674 QESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKV 733
+ + H H + C C K F V L +H LY C+ C + F
Sbjct: 115 KPEFIIHQKTHMREKP--FKCNECGKSFFQVSSLFRHQRIHTGEKLYECSQCGKGFSYNS 172
Query: 734 SIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTE 793
+ +H + H+ E+ + CT C F +++ L++H K H G +++ CI CG+ F +
Sbjct: 173 DLSIHEKI-HTGERH-HECTDCGKAFTQKSTLKMHQK-IHTGE--RSYICIECGQAFIQK 227
Query: 794 VELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFD-AATENGT--ANGVPPM 848
L H I T K Y C C K+F + L+ H R V TE G +N +
Sbjct: 228 THLIAHRRIHTGEKPYECSNCGKSFISKSQLQVHQRVHTRVKPYICTEYGKVFSNNSNLV 287
Query: 849 ATKKAEPADLQGMLLKNPEA--PNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRL 906
KK + + + + +A S + E Y C CG A+T + L H+
Sbjct: 288 THKKVQSREKSSICTECGKAFTYRSELIIHQRIHTGEKPYECSDCGKAFTQKSALTVHQ- 346
Query: 907 RDHNIRPGEDD--------GSRKKAEFI--------KGSHKCNVCSRTFFSENGLREHLQ 950
I GE +KA I + HKC C + F S++ L H +
Sbjct: 347 ---RIHTGEKSYICMKCGLAFIQKAHLIAHQIIHTGEKPHKCGHCGKLFTSKSQLHVHKR 403
Query: 951 THRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMH 1010
H G K YMC CG+ F + L H+ TH+ + C C + I H ++H
Sbjct: 404 IHTGE-KPYMCNKCGKAFTNRSNLITHQKTHTGE-KSYICSKCGKAFTQRSDLITHQRIH 461
Query: 1011 PDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCL 1070
+ + C C + T L IH H ++ Y+C C
Sbjct: 462 TGEKP----YECNTCGKAFTQKSHLNIHQKIHTG----------------ERQYECHECG 501
Query: 1071 KEFRSKQDLV---KLDVNGLPYGLCAGC---MARSANGQVGGLAPPEPADRPCAGLRCPE 1124
K F K L+ K+ PY +C C R +N ++P C +
Sbjct: 502 KAFNQKSILIVHQKIHTGEKPY-VCTECGRAFIRKSNFITHQRI--HTGEKP---YECSD 555
Query: 1125 CSVKFESAEDLESHMQVDHRDLTPETSGPRKGTQTSPVPRKKTYQCIKCQMTFENEREIQ 1184
C F S L H V + K Y C +C F +
Sbjct: 556 CGKSFTSKSQLLVHQPVHTGE--------------------KPYVCAECGKAFSGRSNLS 595
Query: 1185 IHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKL 1244
H H E+ + C C + F ++L+ H H+ E ++C C F + ++L
Sbjct: 596 KHQKTHTGEKP--YICSECGKTFRQKSELITHHRIHTGEK---PYECSDCGKSFTKKSQL 650
Query: 1245 QQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNH 1277
Q H +H E K Y C++C + F ++ L H
Sbjct: 651 QVHQ-RIHTGE-KPYVCAECGKAFTDRSNLNKH 681
Score = 146 bits (369), Expect = 1e-34
Identities = 163/707 (23%), Positives = 261/707 (36%), Gaps = 142/707 (20%)
Query: 414 CSKRD--FNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHV--RKLHKNHAY 469
C+K + F + L++HLK + +K +C++ E + +K H
Sbjct: 77 CAKFEKIFTQKSQLKVHLKVLAGEK------LYVCIECGKAFVQKPEFIIHQKTHMRE-- 128
Query: 470 PVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTE 529
F CN C + F ++SL H R+ G + C+QC GF
Sbjct: 129 --------KPFKCNECGKSFFQVSSLFRHQRIH---------TGEKLYECSQCGKGFSYN 171
Query: 530 SSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHK 589
S L+ H + + + C C + S LK+
Sbjct: 172 SDLSIH------------------EKIHTGERHHECTDCGKAFTQKSTLKM--------- 204
Query: 590 NIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSISNGE--YPCNQCDLKFSNFESF 647
H K E+S + + + ++ L A I GE Y C+ C F +
Sbjct: 205 -----HQKIHTGERSYICIECGQAFIQKTHLIAHRR-IHTGEKPYECSNCGKSFISKSQL 258
Query: 648 QTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDL 707
Q H ++H + + C + + F + +L+ H V S+ +C C K F+ +L
Sbjct: 259 QVHQRVHTRV--KPYICTEYGKVFSNNSNLVTHKKVQSREKSS--ICTECGKAFTYRSEL 314
Query: 708 QKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQV 767
H Y C+ C + F K ++ VH + H+ EK Y C C F ++A L
Sbjct: 315 IIHQRIHTGEKPYECSDCGKAFTQKSALTVHQRI-HTGEKS-YICMKCGLAFIQKAHL-- 370
Query: 768 HVKHSHLGNPAKAHKCIFCGETFSTEVELQCH--ITTHSKKYNCKFCSKAF----HAIIL 821
+ H + K HKC CG+ F+++ +L H I T K Y C C KAF + I
Sbjct: 371 -IAHQIIHTGEKPHKCGHCGKLFTSKSQLHVHKRIHTGEKPYMCNKCGKAFTNRSNLITH 429
Query: 822 LEKHLREKHCV-----------FDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAPN 870
+ H EK + D T G P A Q
Sbjct: 430 QKTHTGEKSYICSKCGKAFTQRSDLITHQRIHTGEKPYECNTCGKAFTQ----------K 479
Query: 871 SHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDD--------GSRKK 922
SH + E Y C CG A+ + +L H+ I GE +K
Sbjct: 480 SHLNIHQKIHTGERQYECHECGKAFNQKSILIVHQ----KIHTGEKPYVCTECGRAFIRK 535
Query: 923 AEFI--------KGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTL 974
+ FI + ++C+ C ++F S++ L H H G K Y+C CG+ F L
Sbjct: 536 SNFITHQRIHTGEKPYECSDCGKSFTSKSQLLVHQPVHTG-EKPYVCAECGKAFSGRSNL 594
Query: 975 TEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLE 1034
++H+ TH+ C C + + E I H ++H + + C C ++ T +
Sbjct: 595 SKHQKTHTGE-KPYICSECGKTFRQKSELITHHRIHTGEK----PYECSDCGKSFTKKSQ 649
Query: 1035 LKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLVK 1081
L++H H +K Y CA C K F + +L K
Sbjct: 650 LQVHQRIHTG----------------EKPYVCAECGKAFTDRSNLNK 680
Score = 134 bits (337), Expect = 6e-31
Identities = 148/669 (22%), Positives = 237/669 (35%), Gaps = 132/669 (19%)
Query: 64 ESIYTCDHCQQDFESLADLTDH-------RAHRCPGDGDDDPQLSWVASSPSSKDVASPT 116
E +Y C C + F +DL+ H R H C G Q S + K
Sbjct: 156 EKLYECSQCGKGFSYNSDLSIHEKIHTGERHHECTDCGKAFTQKSTLKMH--QKIHTGER 213
Query: 117 QMIGDGCDLG-------LGEEEGGTG-LPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKC 168
I C + TG PY C C KSFI S L+ H+++H+ P+ C
Sbjct: 214 SYICIECGQAFIQKTHLIAHRRIHTGEKPYECSNCGKSFISKSQLQVHQRVHTRVKPYIC 273
Query: 169 TYCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCK 228
T ++F + + H K+ + +K C EC AF+ L IH + H+ KP++C+ C
Sbjct: 274 TEYGKVFSNNSNLVTHKKVQSREKSSICTECGKAFTYRSELIIHQRIHTGEKPYECSDCG 333
Query: 229 RGFSSTSSLQSHMQAHKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQ 288
+ F+ S+L H + H K ++C C F Q L H + +
Sbjct: 334 KAFTQKSALTVHQRIHTGEK-------------SYICMKCGLAFIQKAHLIAHQIIHTGE 380
Query: 289 LSEKADLQCIHCPEVFVDENTLLAHIH-QAHANQK-HKCPMCPEQFSSVEGVYCHLDSHR 346
K C HC ++F ++ L H+H + H +K + C C + F++ + H +H
Sbjct: 381 KPHK----CGHCGKLFTSKSQL--HVHKRIHTGEKPYMCNKCGKAFTNRSNLITHQKTHT 434
Query: 347 QPDSSNHSVSPDPVLGSVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTK 406
S + S + + +R T + KP
Sbjct: 435 GEKS---------YICSKCGKAFTQRSDLITHQRIHTGE---KP---------------- 466
Query: 407 VVYSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKN 466
Y C C K F + L IH K ++ + H C + L H +K+H
Sbjct: 467 --YECNTCGKA-FTQKSHLNIHQKIHTGERQYECHECGKAFNQKSILI---VH-QKIHTG 519
Query: 467 HAYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGF 526
+ C C F ++ H R+ G + C+ C F
Sbjct: 520 E----------KPYVCTECGRAFIRKSNFITHQRI---------HTGEKPYECSDCGKSF 560
Query: 527 LTESSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKE 586
++S L H QP + + Y C C + F L+KH K
Sbjct: 561 TSKSQLLVH------------------QPVHTGEKPYVCAECGKA--FSGRSNLSKHQKT 600
Query: 587 NHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFES 646
+ P S+ K + K + ++ Y C+ C F+
Sbjct: 601 HTGEKPYICSECGKTFRQ-----------KSELITHHRIHTGEKPYECSDCGKSFTKKSQ 649
Query: 647 FQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDD 706
Q H ++H + C +C + F + +L +H T H T Y C C K F
Sbjct: 650 LQVHQRIHTG--EKPYVCAECGKAFTDRSNLNKHQTTH--TGDKPYKCGICGKGF----- 700
Query: 707 LQKHLLDMH 715
+QK + +H
Sbjct: 701 VQKSVFSVH 709
Score = 126 bits (316), Expect = 2e-28
Identities = 151/630 (23%), Positives = 240/630 (38%), Gaps = 101/630 (16%)
Query: 408 VYSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNH 467
+Y C C K F+ + L IH K IH ++ H C C + L H +K+H
Sbjct: 158 LYECSQCGK-GFSYNSDLSIHEK-IHTG--ERHHECTDCGKAFTQKSTLKMH-QKIHTGE 212
Query: 468 AYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFL 527
++ C C + F L H R+ G + C+ C F+
Sbjct: 213 R----------SYICIECGQAFIQKTHLIAHRRIH---------TGEKPYECSNCGKSFI 253
Query: 528 TESSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVYSCPY-CTNSPIFGSILKLTKHIKE 586
++S L H Q+ H V PY CT +G +
Sbjct: 254 SKSQLQVH-QRVHTRVK---------------------PYICTE---YGKVFS------- 281
Query: 587 NHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSISNGE--YPCNQCDLKFSNF 644
N+ N+ + H K E+S + ++ + R L I GE Y C+ C F+
Sbjct: 282 NNSNL-VTHKKVQSREKSSICTECGKAFTYRSELIIHQR-IHTGEKPYECSDCGKAFTQK 339
Query: 645 ESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSV 704
+ H ++H + C +C F + L+ H +H T + C C K F+S
Sbjct: 340 SALTVHQRIHTGE--KSYICMKCGLAFIQKAHLIAHQIIH--TGEKPHKCGHCGKLFTSK 395
Query: 705 DDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEAD 764
L H Y C C + F ++ ++ H H+ EK Y C+ C F + +D
Sbjct: 396 SQLHVHKRIHTGEKPYMCNKCGKAFTNRSNLITHQKT-HTGEKS-YICSKCGKAFTQRSD 453
Query: 765 LQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCH--ITTHSKKYNCKFCSKAFH--AII 820
L + H + K ++C CG+ F+ + L H I T ++Y C C KAF+ +I+
Sbjct: 454 L---ITHQRIHTGEKPYECNTCGKAFTQKSHLNIHQKIHTGERQYECHECGKAFNQKSIL 510
Query: 821 LLEK--HLREKHCVFDAATENGTA-----NGVPPMATKKAE-PADLQGMLLKNPEAPNSH 872
++ + H EK V TE G A N + E P + S
Sbjct: 511 IVHQKIHTGEKPYV---CTECGRAFIRKSNFITHQRIHTGEKPYECSDC--GKSFTSKSQ 565
Query: 873 EASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPG--EDDGS--RKKAEFI-- 926
V E Y C CG A++ L H+ +P + G R+K+E I
Sbjct: 566 LLVHQPVHTGEKPYVCAECGKAFSGRSNLSKHQKTHTGEKPYICSECGKTFRQKSELITH 625
Query: 927 ------KGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVT 980
+ ++C+ C ++F ++ L+ H + H G K Y+C CG+ F L +H+ T
Sbjct: 626 HRIHTGEKPYECSDCGKSFTKKSQLQVHQRIHTGE-KPYVCAECGKAFTDRSNLNKHQTT 684
Query: 981 HSKSLDTGTCRICKMPLQSEEEFIEHCQMH 1010
H+ C IC + F H H
Sbjct: 685 HTGD-KPYKCGICGKGFVQKSVFSVHQSSH 713
Score = 118 bits (296), Expect = 3e-26
Identities = 82/331 (24%), Positives = 141/331 (42%), Gaps = 42/331 (12%)
Query: 31 EPECDQKTSRALEDRNSVTSQEERNEDDEDMEDESIYTCDHCQQDFESLADLTDH-RAHR 89
+P K +A +R+++ + ++ + ++ Y C C + F +DL H R H
Sbjct: 409 KPYMCNKCGKAFTNRSNLITHQKTHTGEKS------YICSKCGKAFTQRSDLITHQRIHT 462
Query: 90 CPGDGDDDPQLSWVASSPSSKDVASPTQMIGDGCDLGLGEEEGGTGLPYPCQFCDKSFIR 149
G+ + + + + K + Q I G E + Y C C K+F +
Sbjct: 463 ----GEKPYECNTCGKAFTQKSHLNIHQKIHTG------ERQ------YECHECGKAFNQ 506
Query: 150 LSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHL 209
S L H++IH+ + P+ CT C R F K + H ++HTG+K Y C +C +F+ L
Sbjct: 507 KSILIVHQKIHTGEKPYVCTECGRAFIRKSNFITHQRIHTGEKPYECSDCGKSFTSKSQL 566
Query: 210 KIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLA---------KSEK---- 256
+H H+ KP+ C C + FS S+L H + H K ++ KSE
Sbjct: 567 LVHQPVHTGEKPYVCAECGKAFSGRSNLSKHQKTHTGEKPYICSECGKTFRQKSELITHH 626
Query: 257 --EAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHI 314
+ + C C +F++ +L+ H + EK + C C + F D + L H
Sbjct: 627 RIHTGEKPYECSDCGKSFTKKSQLQVH---QRIHTGEKPYV-CAECGKAFTDRSNLNKHQ 682
Query: 315 HQAHANQKHKCPMCPEQFSSVEGVYCHLDSH 345
++ +KC +C + F H SH
Sbjct: 683 TTHTGDKPYKCGICGKGFVQKSVFSVHQSSH 713
Score = 103 bits (257), Expect = 1e-21
Identities = 54/183 (29%), Positives = 82/183 (44%), Gaps = 18/183 (9%)
Query: 137 PYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 196
PY C C KSF S L H+ +H+ + P+ C C + F + + +H K HTG+K Y C
Sbjct: 550 PYECSDCGKSFTSKSQLLVHQPVHTGEKPYVCAECGKAFSGRSNLSKHQKTHTGEKPYIC 609
Query: 197 HECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEK 256
EC F + L H + H+ KP++C+ C + F+ S LQ H + H K
Sbjct: 610 SECGKTFRQKSELITHHRIHTGEKPYECSDCGKSFTKKSQLQVHQRIHTGEK-------- 661
Query: 257 EAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQ 316
++C C F+ L KH T + +C C + FV ++ H
Sbjct: 662 -----PYVCAECGKAFTDRSNLNKHQTTH----TGDKPYKCGICGKGFVQKSVFSVH-QS 711
Query: 317 AHA 319
+HA
Sbjct: 712 SHA 714
>gi|156627573 zinc finger protein 836 [Homo sapiens]
Length = 936
Score = 193 bits (491), Expect = 8e-49
Identities = 205/866 (23%), Positives = 327/866 (37%), Gaps = 164/866 (18%)
Query: 144 DKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAF 203
+ F++LS + E+ H + P+ C C + F+ S H +HT +K Y C+EC AF
Sbjct: 196 ENEFLQLSLPTQLEKTHIREKPYMCKGCGKAFRVSSSLINHQMVHTTEKPYKCNECGKAF 255
Query: 204 SRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEKEAKKDDF 263
R L IH H+ KP++C VC + F S L +H ++H K +
Sbjct: 256 HRGSLLTIHQIVHTRGKPYQCGVCGKIFRQNSDLVNHRRSHTGEKP-------------Y 302
Query: 264 MCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQAHANQKH 323
C+ C +FSQ+ L H + EK +C C + F + L H + +
Sbjct: 303 KCNECGKSFSQSYNLAIH---QRIHTGEKP-YKCNECGKTFKQGSCLTTHQIIHTGEKPY 358
Query: 324 KCPMCPEQFSSVEGVYCHLDSH--RQPDSSNHSVSPDPVLGSVASMSSATPDSSASVERG 381
+C +C + F + H H +P N + G S SS + +V G
Sbjct: 359 QCDICGKVFRQNSNLVNHQRIHTGEKPYKCN-------ICGKSFSQSSNLA-THQTVHSG 410
Query: 382 STPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSH 441
+ P Y C C K F + L H +KP +
Sbjct: 411 NKP------------------------YKCDECGKT-FKRSSSLTTHQIIHTGEKP---Y 442
Query: 442 TCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINSLQEHIRV 501
TC +C +++ + + ++H + CN C ++F+ + L H R+
Sbjct: 443 TCDVC----DKVFSQRSQLARHQRSHT-------GEKPYKCNECGKVFSQTSHLVGHRRI 491
Query: 502 SHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPTQSFME 561
G + C++C F S LT H ++ + +
Sbjct: 492 H---------TGEKPYKCDKCGKAFKQGSLLTRH---------------KIIHTRE---K 524
Query: 562 VYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLS 621
Y C C +F L +H++ + P + K + +S KR
Sbjct: 525 RYQCGEC--GKVFSENSCLVRHLRIHTGEQPYKCNVCGKV----FNYSGNLSIHKR---- 574
Query: 622 ASANSISNGEYP--CNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQ 679
I GE P CN+C F N+ HL++H + C C + F+ +L
Sbjct: 575 -----IHTGEKPFQCNECGTVFRNYSCLARHLRIHTGQ--KPYKCNVCGKVFNDSGNLSN 627
Query: 680 HLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVL-YHCTLCQEVFDSKVSIQVH 738
H +H T + C C K FS L +H +HT Y C C + + + S+ H
Sbjct: 628 HKRIH--TGEKPFQCNECGKVFSYYSCLARHR-KIHTGEKPYKCNDCGKAYTQRSSLTKH 684
Query: 739 LAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPA--KAHKCIFCGETFSTEVEL 796
L + H+ EK Y C F + + L + + NP K HKC CG TFS L
Sbjct: 685 LII-HTGEKP-YNCNEFGGAFIQSSKLARYHR-----NPTGEKPHKCSHCGRTFSHITGL 737
Query: 797 QCHITTHSKK--YNCKFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAE 854
H H+ + Y C C + F++ L +H R G P +
Sbjct: 738 TYHQRRHTGEMPYKCIECGQVFNSTSNLARHRR-------------IHTGEKPYKCNEC- 783
Query: 855 PADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRP- 913
G + ++ H + + E Y C+ CG A+ + +L NH+ +P
Sbjct: 784 -----GKVFRHQSTLARHRS----IHTGEKPYVCNECGKAFRVRSILVNHQKMHTGDKPY 834
Query: 914 -----GEDDGSRKKAEFIKGSH------KCNVCSRTFFSENGLREHLQTHRGPAKHYMCP 962
G+ R K + + +H KC C + F + L +H H G K Y C
Sbjct: 835 KCNECGKAFIERSKLVYHQRNHTGEKPYKCIECGKAFGRFSCLNKHQMIHSGE-KPYKCN 893
Query: 963 ICGERFPSLLTLTEHKVTH-SKSLDT 987
CG+ F S LT+H+ H ++SL T
Sbjct: 894 ECGKSFISRSGLTKHQTKHTAESLKT 919
Score = 193 bits (490), Expect = 1e-48
Identities = 192/740 (25%), Positives = 288/740 (38%), Gaps = 112/740 (15%)
Query: 134 TGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKK 193
T PY C C K+F R S L H+ +H+ P++C C ++F+ H + HTG+K
Sbjct: 242 TEKPYKCNECGKAFHRGSLLTIHQIVHTRGKPYQCGVCGKIFRQNSDLVNHRRSHTGEKP 301
Query: 194 YHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAH--------- 244
Y C+EC +FS+S +L IH + H+ KP+KC C + F S L +H H
Sbjct: 302 YKCNECGKSFSQSYNLAIHQRIHTGEKPYKCNECGKTFKQGSCLTTHQIIHTGEKPYQCD 361
Query: 245 ------KKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCI 298
++N + + + C+ C +FSQ+ L H S +C
Sbjct: 362 ICGKVFRQNSNLVNHQRIHTGEKPYKCNICGKSFSQSSNLATHQTVH----SGNKPYKCD 417
Query: 299 HCPEVFVDENTLLAHIHQAHANQKHKCPMCPEQFSSVEGVYCHLDSH--RQPDSSNHSVS 356
C + F ++L H + + C +C + FS + H SH +P N
Sbjct: 418 ECGKTFKRSSSLTTHQIIHTGEKPYTCDVCDKVFSQRSQLARHQRSHTGEKPYKCNE--- 474
Query: 357 PDPVLGSVASMSSATPDSSASVERGSTP---DSTLKPLR-GQKKMRDDGQGWTKVVYSCP 412
G V S +S + G P D K + G R + Y C
Sbjct: 475 ----CGKVFSQTSHLV-GHRRIHTGEKPYKCDKCGKAFKQGSLLTRHKIIHTREKRYQCG 529
Query: 413 YCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVM 472
C K F+ + L HL+ IH +Q + C +C NL+ H +++H
Sbjct: 530 ECGK-VFSENSCLVRHLR-IHTG--EQPYKCNVCGKVFNYSGNLSIH-KRIHTGE----- 579
Query: 473 QFGNISAFHCNYCPEMFADINSLQEHIRV---------SHCGPNANPS----------DG 513
F CN C +F + + L H+R+ + CG N S G
Sbjct: 580 -----KPFQCNECGTVFRNYSCLARHLRIHTGQKPYKCNVCGKVFNDSGNLSNHKRIHTG 634
Query: 514 NNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPI 573
F CN+C F S L H ++ H E P Y C C +
Sbjct: 635 EKPFQCNECGKVFSYYSCLARH-RKIHTG------EKP-----------YKCNDCGKA-- 674
Query: 574 FGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSISNGEYP 633
+ LTKH+ + H+ + K + S K R N +
Sbjct: 675 YTQRSSLTKHL--------IIHTGE-KPYNCNEFGGAFIQSSKLARY--HRNPTGEKPHK 723
Query: 634 CNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYV 693
C+ C FS+ H + H + K C +C + F+S +L +H +H T Y
Sbjct: 724 CSHCGRTFSHITGLTYHQRRHTGEMPYK--CIECGQVFNSTSNLARHRRIH--TGEKPYK 779
Query: 694 CESCDKQFSSVDDLQKHLLDMHTFVL-YHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRC 752
C C K F L +H +HT Y C C + F + SI V+ H+ +K Y+C
Sbjct: 780 CNECGKVFRHQSTLARH-RSIHTGEKPYVCNECGKAFRVR-SILVNHQKMHTGDKP-YKC 836
Query: 753 TACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHITTHS--KKYNCK 810
C F + + L H + +H G K +KCI CG+ F L H HS K Y C
Sbjct: 837 NECGKAFIERSKLVYH-QRNHTGE--KPYKCIECGKAFGRFSCLNKHQMIHSGEKPYKCN 893
Query: 811 FCSKAFHAIILLEKHLREKH 830
C K+F + L KH + KH
Sbjct: 894 ECGKSFISRSGLTKH-QTKH 912
Score = 189 bits (479), Expect = 2e-47
Identities = 177/755 (23%), Positives = 277/755 (36%), Gaps = 182/755 (24%)
Query: 64 ESIYTCDHCQQDFESLADLTDHRAHRCPGDGDDDPQLSWVASSPSSKDVASPTQMIGDGC 123
E Y C+ C + F+ + LT H Q+ P D+ ++
Sbjct: 327 EKPYKCNECGKTFKQGSCLTTH-------------QIIHTGEKPYQCDICG--KVFRQNS 371
Query: 124 DLGLGEEEGGTG-LPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRD 182
+L + + TG PY C C KSF + S L H+ +HS P+KC C + FK S
Sbjct: 372 NL-VNHQRIHTGEKPYKCNICGKSFSQSSNLATHQTVHSGNKPYKCDECGKTFKRSSSLT 430
Query: 183 RHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQ 242
H +HTG+K Y C C+ FS+ L H ++H+ KP+KC C + FS TS L H +
Sbjct: 431 THQIIHTGEKPYTCDVCDKVFSQRSQLARHQRSHTGEKPYKCNECGKVFSQTSHLVGHRR 490
Query: 243 AHKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPE 302
H K + CD C F Q L +H + + + QC C +
Sbjct: 491 IHTGEK-------------PYKCDKCGKAFKQGSLLTRHKIIH----TREKRYQCGECGK 533
Query: 303 VFVDENTLLAHIHQAHANQKHKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLG 362
VF + + L+ H+ Q +KC +C + F+ + H H
Sbjct: 534 VFSENSCLVRHLRIHTGEQPYKCNVCGKVFNYSGNLSIHKRIH----------------- 576
Query: 363 SVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSL 422
G+K + + G YSC
Sbjct: 577 -----------------------------TGEKPFQCNECGTVFRNYSC----------- 596
Query: 423 AVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHC 482
L HL+ KP + C +C NL+ H +++H F C
Sbjct: 597 --LARHLRIHTGQKP---YKCNVCGKVFNDSGNLSNH-KRIHTGE----------KPFQC 640
Query: 483 NYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHI------ 536
N C ++F+ + L H ++ G + CN C + SSLT+H+
Sbjct: 641 NECGKVFSYYSCLARHRKI---------HTGEKPYKCNDCGKAYTQRSSLTKHLIIHTGE 691
Query: 537 QQAHCS------VGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKN 590
+ +C+ + S+KL PT + + C +C + F I LT H + +
Sbjct: 692 KPYNCNEFGGAFIQSSKLARYHRNPTGE--KPHKCSHCGRT--FSHITGLTYHQRRHTGE 747
Query: 591 IPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTH 650
+P Y C +C F++ + H
Sbjct: 748 MP---------------------------------------YKCIECGQVFNSTSNLARH 768
Query: 651 LKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKH 710
++H + C +C + F Q +L +H ++H T YVC C K F L H
Sbjct: 769 RRIHTG--EKPYKCNECGKVFRHQSTLARHRSIH--TGEKPYVCNECGKAFRVRSILVNH 824
Query: 711 LLDMHT-FVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHV 769
MHT Y C C + F + + H H+ EK Y+C C F + + L
Sbjct: 825 -QKMHTGDKPYKCNECGKAFIERSKLVYHQR-NHTGEKP-YKCIECGKAFGRFSCLN--- 878
Query: 770 KHSHLGNPAKAHKCIFCGETFSTEVELQCHITTHS 804
KH + + K +KC CG++F + L H T H+
Sbjct: 879 KHQMIHSGEKPYKCNECGKSFISRSGLTKHQTKHT 913
Score = 182 bits (462), Expect = 2e-45
Identities = 192/823 (23%), Positives = 309/823 (37%), Gaps = 134/823 (16%)
Query: 137 PYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 196
PY C+ C K+F S L H+ +H+ + P+KC C + F H +HT K Y C
Sbjct: 217 PYMCKGCGKAFRVSSSLINHQMVHTTEKPYKCNECGKAFHRGSLLTIHQIVHTRGKPYQC 276
Query: 197 HECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEK 256
C F ++ L H ++H+ KP+KC C + FS + +L H + H K
Sbjct: 277 GVCGKIFRQNSDLVNHRRSHTGEKPYKCNECGKSFSQSYNLAIHQRIHTGEK-------- 328
Query: 257 EAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQ 316
+ C+ C TF Q L H + + + QC C +VF + L+ H +
Sbjct: 329 -----PYKCNECGKTFKQGSCLTTHQIIH----TGEKPYQCDICGKVFRQNSNLVNH-QR 378
Query: 317 AHANQK-HKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDSS 375
H +K +KC +C + FS +L +H+ S N D + SS T
Sbjct: 379 IHTGEKPYKCNICGKSFSQSS----NLATHQTVHSGNKPYKCDECGKTFKRSSSLTTHQI 434
Query: 376 ASV-ERGSTPDSTLKPLRGQKKMRDDGQGWT-KVVYSCPYCSKRDFNSLAVLEIHLKTIH 433
E+ T D K + ++ + T + Y C C K F+ + L H +
Sbjct: 435 IHTGEKPYTCDVCDKVFSQRSQLARHQRSHTGEKPYKCNECGK-VFSQTSHLVGHRRIHT 493
Query: 434 ADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADIN 493
+KP + C C + L H + +H + C C ++F++ +
Sbjct: 494 GEKP---YKCDKCGKAFKQGSLLTRH-KIIHTRE----------KRYQCGECGKVFSENS 539
Query: 494 SLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVV 553
L H+R+ G + CN C F +L+ H ++ H E P
Sbjct: 540 CLVRHLRI---------HTGEQPYKCNVCGKVFNYSGNLSIH-KRIHTG------EKP-- 581
Query: 554 QPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVS 613
+ C C +F + L +H++ + P + K + +S
Sbjct: 582 ---------FQCNEC--GTVFRNYSCLARHLRIHTGQKPYKCNVCGKV----FNDSGNLS 626
Query: 614 SPKRQRLSASANSISNGEYP--CNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDF 671
+ KR I GE P CN+C FS + H K+H + C C + +
Sbjct: 627 NHKR---------IHTGEKPFQCNECGKVFSYYSCLARHRKIHTG--EKPYKCNDCGKAY 675
Query: 672 DSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDS 731
+ SL +HL +H T Y C F L ++ + + C+ C F
Sbjct: 676 TQRSSLTKHLIIH--TGEKPYNCNEFGGAFIQSSKLARYHRNPTGEKPHKCSHCGRTFSH 733
Query: 732 KVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFS 791
+ H +H+ E Y+C C F ++L +H + K +KC CG+ F
Sbjct: 734 ITGLTYHQR-RHTGEMP-YKCIECGQVFNSTSNL---ARHRRIHTGEKPYKCNECGKVFR 788
Query: 792 TEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMA 849
+ L H + H+ K Y C C KAF +L H ++ H G P
Sbjct: 789 HQSTLARHRSIHTGEKPYVCNECGKAFRVRSILVNH-QKMH------------TGDKPYK 835
Query: 850 TKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDH 909
+ A ++ L H+ + E Y C CG A+ L H++
Sbjct: 836 CNECGKAFIERSKLV------YHQRNH----TGEKPYKCIECGKAFGRFSCLNKHQM--- 882
Query: 910 NIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTH 952
I GE +KCN C ++F S +GL +H H
Sbjct: 883 -IHSGEK------------PYKCNECGKSFISRSGLTKHQTKH 912
Score = 144 bits (364), Expect = 4e-34
Identities = 185/807 (22%), Positives = 275/807 (34%), Gaps = 148/807 (18%)
Query: 517 FFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGS 576
+ C C F SSL H Q H + E P Y C C + GS
Sbjct: 218 YMCKGCGKAFRVSSSLINH-QMVHTT------EKP-----------YKCNECGKAFHRGS 259
Query: 577 ILKLTKHIKENHK-------------NIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSAS 623
+L + + + K N L + ++S + P + S + A
Sbjct: 260 LLTIHQIVHTRGKPYQCGVCGKIFRQNSDLVNHRRSHTGEKPYKCNECGKSFSQSYNLAI 319
Query: 624 ANSISNGE--YPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHL 681
I GE Y CN+C F TH +H + C C + F +L+ H
Sbjct: 320 HQRIHTGEKPYKCNECGKTFKQGSCLTTHQIIHTGE--KPYQCDICGKVFRQNSNLVNHQ 377
Query: 682 TVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAV 741
+H T Y C C K FS +L H Y C C + F S+ H +
Sbjct: 378 RIH--TGEKPYKCNICGKSFSQSSNLATHQTVHSGNKPYKCDECGKTFKRSSSLTTHQII 435
Query: 742 KHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCH-- 799
H+ EK Y C C+ F + + L H + SH G K +KC CG+ FS L H
Sbjct: 436 -HTGEKP-YTCDVCDKVFSQRSQLARH-QRSHTGE--KPYKCNECGKVFSQTSHLVGHRR 490
Query: 800 ITTHSKKYNCKFCSKAFHAIILLEKH----LREKHCVFDAATENGTANGVPPMATKKAEP 855
I T K Y C C KAF LL +H REK + G V
Sbjct: 491 IHTGEKPYKCDKCGKAFKQGSLLTRHKIIHTREKRY------QCGECGKV---------- 534
Query: 856 ADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGE 915
+ NS + E Y C++CG + L H+ I GE
Sbjct: 535 -----------FSENSCLVRHLRIHTGEQPYKCNVCGKVFNYSGNLSIHK----RIHTGE 579
Query: 916 DDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLT 975
+CN C F + + L HL+ H G K Y C +CG+ F L+
Sbjct: 580 KP------------FQCNECGTVFRNYSCLARHLRIHTGQ-KPYKCNVCGKVFNDSGNLS 626
Query: 976 EHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLEL 1035
HK H+ C C H ++H + ++C C + T L
Sbjct: 627 NHKRIHTGEKPF-QCNECGKVFSYYSCLARHRKIHTGEKP----YKCNDCGKAYTQRSSL 681
Query: 1036 KIHGTFHM-------QKLAGSSAASS--------PNGQGLQKLYKCALCLKEFRSKQDLV 1080
H H + G+ SS P G+ K +KC+ C + F L
Sbjct: 682 TKHLIIHTGEKPYNCNEFGGAFIQSSKLARYHRNPTGE---KPHKCSHCGRTFSHITGLT 738
Query: 1081 ---KLDVNGLPYGLCAGCMARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLES 1137
+ +PY ++ + ++P +C EC F L
Sbjct: 739 YHQRRHTGEMPYKCIECGQVFNSTSNLARHRRIHTGEKP---YKCNECGKVFRHQSTLAR 795
Query: 1138 HMQVDHRDLTPETSGPRKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEGIN 1197
H + + K Y C +C F + H H ++
Sbjct: 796 HRSIHTGE--------------------KPYVCNECGKAFRVRSILVNHQKMHTGDKP-- 833
Query: 1198 HECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDK 1257
++C C + F +KL+ H H+ E +KC C F + + L +H G+ K
Sbjct: 834 YKCNECGKAFIERSKLVYHQRNHTGEK---PYKCIECGKAFGRFSCLNKHQMIHSGE--K 888
Query: 1258 IYDCSQCPQKFFFQTELQNHTMSQHAQ 1284
Y C++C + F ++ L H A+
Sbjct: 889 PYKCNECGKSFISRSGLTKHQTKHTAE 915
Score = 135 bits (340), Expect = 3e-31
Identities = 120/529 (22%), Positives = 200/529 (37%), Gaps = 78/529 (14%)
Query: 64 ESIYTCDHCQQDFESLADLTDH-------RAHRCPGDGDDDPQLSWVASSPSSKDVASPT 116
E YTCD C + F + L H + ++C G Q S + P
Sbjct: 439 EKPYTCDVCDKVFSQRSQLARHQRSHTGEKPYKCNECGKVFSQTSHLVGHRRIHTGEKPY 498
Query: 117 QMIGDGCDLGLGEEEGGT----------GLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPF 166
+ D C G ++G Y C C K F S L RH +IH+ + P+
Sbjct: 499 KC--DKC--GKAFKQGSLLTRHKIIHTREKRYQCGECGKVFSENSCLVRHLRIHTGEQPY 554
Query: 167 KCTYCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTV 226
KC C ++F + + H ++HTG+K + C+EC F L HL+ H+ KP+KC V
Sbjct: 555 KCNVCGKVFNYSGNLSIHKRIHTGEKPFQCNECGTVFRNYSCLARHLRIHTGQKPYKCNV 614
Query: 227 CKRGFSSTSSLQSHMQAHKKNKEH--------------LAKSEK-EAKKDDFMCDYCEDT 271
C + F+ + +L +H + H K LA+ K + + C+ C
Sbjct: 615 CGKVFNDSGNLSNHKRIHTGEKPFQCNECGKVFSYYSCLARHRKIHTGEKPYKCNDCGKA 674
Query: 272 FSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQAHANQKHKCPMCPEQ 331
++Q L KH++ + + C F+ + L + + HKC C
Sbjct: 675 YTQRSSLTKHLIIH----TGEKPYNCNEFGGAFIQSSKLARYHRNPTGEKPHKCSHCGRT 730
Query: 332 FSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDSSASVERGSTP---DSTL 388
FS + G+ H H + + V S ++++ + G P +
Sbjct: 731 FSHITGLTYHQRRHTG-EMPYKCIECGQVFNSTSNLAR-----HRRIHTGEKPYKCNECG 784
Query: 389 KPLRGQKKMRDDGQGWT-KVVYSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTC-QIC 446
K R Q + T + Y C C K F ++L H K DKP + + C +
Sbjct: 785 KVFRHQSTLARHRSIHTGEKPYVCNECGKA-FRVRSILVNHQKMHTGDKPYKCNECGKAF 843
Query: 447 LDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGP 506
++ +Y+ H + + C C + F + L +H +
Sbjct: 844 IERSKLVYHQRNHTGE---------------KPYKCIECGKAFGRFSCLNKHQMIH---- 884
Query: 507 NANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQP 555
G + CN+C F++ S LT+H Q + S K + V +P
Sbjct: 885 -----SGEKPYKCNECGKSFISRSGLTKH--QTKHTAESLKTKFNVEKP 926
Score = 94.0 bits (232), Expect = 8e-19
Identities = 99/446 (22%), Positives = 157/446 (35%), Gaps = 83/446 (18%)
Query: 883 EPMYGCDICGAAYTMEVLLQNHR-----------------------LRDHNI-------- 911
E Y C CG A+ + L NH+ L H I
Sbjct: 215 EKPYMCKGCGKAFRVSSSLINHQMVHTTEKPYKCNECGKAFHRGSLLTIHQIVHTRGKPY 274
Query: 912 ---------RPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCP 962
R D + +++ + +KCN C ++F L H + H G K Y C
Sbjct: 275 QCGVCGKIFRQNSDLVNHRRSHTGEKPYKCNECGKSFSQSYNLAIHQRIHTG-EKPYKCN 333
Query: 963 ICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRC 1022
CG+ F LT H++ H+ C IC + + H ++H + ++C
Sbjct: 334 ECGKTFKQGSCLTTHQIIHTGE-KPYQCDICGKVFRQNSNLVNHQRIHTGEK----PYKC 388
Query: 1023 VVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLVK- 1081
+C ++ + + L H T H K YKC C K F+ L
Sbjct: 389 NICGKSFSQSSNLATHQTVHSG----------------NKPYKCDECGKTFKRSSSLTTH 432
Query: 1082 --LDVNGLPYGLCAGCMARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHM 1139
+ PY S Q+ ++P +C EC F L H
Sbjct: 433 QIIHTGEKPYTCDVCDKVFSQRSQLARHQRSHTGEKP---YKCNECGKVFSQTSHLVGHR 489
Query: 1140 QVDHRDLTPETSGPRKGTQTSPV--------PRKKTYQCIKCQMTFENEREIQIHVANHM 1191
++ + + K + + R+K YQC +C F + H+ H
Sbjct: 490 RIHTGEKPYKCDKCGKAFKQGSLLTRHKIIHTREKRYQCGECGKVFSENSCLVRHLRIHT 549
Query: 1192 IEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAV 1251
E+ ++C +C ++F+ L H H+ E F+C C TVF + L +H+
Sbjct: 550 GEQ--PYKCNVCGKVFNYSGNLSIHKRIHTGE---KPFQCNECGTVFRNYSCLARHLRIH 604
Query: 1252 HGQEDKIYDCSQCPQKFFFQTELQNH 1277
GQ K Y C+ C + F L NH
Sbjct: 605 TGQ--KPYKCNVCGKVFNDSGNLSNH 628
>gi|209954795 zinc finger protein 761 [Homo sapiens]
Length = 746
Score = 189 bits (479), Expect = 2e-47
Identities = 171/670 (25%), Positives = 257/670 (38%), Gaps = 146/670 (21%)
Query: 138 YPCQFCDKSFIRLSYLKRHEQIH-SDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 196
+ C K+F S L++H+ IH +DK +KC C +LF KR+ H + HTG+ Y C
Sbjct: 215 FQCNESGKAFNYSSLLRKHQIIHLADK--YKCDVCGKLFNQKRNLACHRRCHTGENPYKC 272
Query: 197 HECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEK 256
+EC FS++ L H + H+ KP+KC C + F S L+ H H + K
Sbjct: 273 NECGKTFSQTSSLTCHRRLHTGEKPYKCEECDKAFHFKSILERHRIIHTEEK-------- 324
Query: 257 EAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQL-SEKADLQCIHCPEVFVDENTLLAHIH 315
+ C+ C TF Q K +LTRH +L + + +C C + F +++L H H
Sbjct: 325 -----PYKCNECGKTFRQ-----KSILTRHHRLHTGEKPYKCNECGKTFSHKSSLTCH-H 373
Query: 316 QAHANQK-HKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDS 374
+ H +K +KC C + FS + CH H T +
Sbjct: 374 RLHTGEKPYKCNECGKTFSHKSSLTCHRRLH-------------------------TGEK 408
Query: 375 SASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHA 434
E S +K+ + Y C C K F+ + L H +
Sbjct: 409 PYKCEECDKAYSFRSNFEIHRKIHTEDN-----AYKCNECGK-TFSRTSSLTCHRRRHTG 462
Query: 435 DKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINS 494
++P + C+ C + NL H R++H + CN C + F+ +
Sbjct: 463 EQP---YKCEECDKAFRFKSNLERH-RRIHTGE----------KPYKCNECGKTFSRKSY 508
Query: 495 LQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQ 554
L H R+ G A+ CN+C F +SSLT H ++ H E P
Sbjct: 509 LTCHHRL---------HTGEKAYKCNECGKTFSWKSSLTCH-RRLHSG------EKP--- 549
Query: 555 PTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSS 614
Y C C + F L L +H
Sbjct: 550 --------YKCKECGKT--FNQQLTLKRH------------------------------- 568
Query: 615 PKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQ 674
+RL + N Y C D +S + + H K+H E C +C + F
Sbjct: 569 ---RRLHSGEN-----PYKCEDSDKAYSFKSNLEIHQKIHTE--ENPYKCNECGKTFSRT 618
Query: 675 ESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVS 734
SL H +H T Y CE CDK F +L+ H Y C C + F K
Sbjct: 619 SSLTCHRRLH--TGEKPYKCEECDKAFRVKSNLEGHRRIHTGEKPYKCNECGKTFSRKSY 676
Query: 735 IQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEV 794
H + H+ EK Y+C C +F +++ L + H L K +KC CG+TFS +
Sbjct: 677 FICHHRL-HTGEKP-YKCNECGKNFSQKSSL---ICHHRLHTGEKPYKCNECGKTFSQKS 731
Query: 795 ELQCHITTHS 804
L CH H+
Sbjct: 732 NLTCHRRLHT 741
Score = 145 bits (365), Expect = 3e-34
Identities = 146/606 (24%), Positives = 230/606 (37%), Gaps = 125/606 (20%)
Query: 67 YTCDHCQQDFESLADLTDHRAHRCPGDGDDDPQLSWVASSPSSKDVASPTQMIGDGCDLG 126
Y CD C + F +L HR RC G++ + + + S T + L
Sbjct: 242 YKCDVCGKLFNQKRNLACHR--RCH-TGENPYKCNECGKT------FSQTSSLTCHRRLH 292
Query: 127 LGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIK 186
GE+ PY C+ CDK+F S L+RH IH+++ P+KC C + F+ K RH +
Sbjct: 293 TGEK------PYKCEECDKAFHFKSILERHRIIHTEEKPYKCNECGKTFRQKSILTRHHR 346
Query: 187 LHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKK 246
LHTG+K Y C+EC FS L H + H+ KP+KC C + FS SSL H + H
Sbjct: 347 LHTGEKPYKCNECGKTFSHKSSLTCHHRLHTGEKPYKCNECGKTFSHKSSLTCHRRLHTG 406
Query: 247 NKEHLAKSEKEA---------------KKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSE 291
K + + +A + + + C+ C TFS+T L H RH +
Sbjct: 407 EKPYKCEECDKAYSFRSNFEIHRKIHTEDNAYKCNECGKTFSRTSSLTCH-RRRH---TG 462
Query: 292 KADLQCIHCPEVFVDENTLLAHIHQAHANQK-HKCPMCPEQFSSVEGVYCHLDSHRQPDS 350
+ +C C + F ++ L H + H +K +KC C + FS + CH H
Sbjct: 463 EQPYKCEECDKAFRFKSNLERH-RRIHTGEKPYKCNECGKTFSRKSYLTCHHRLH----- 516
Query: 351 SNHSVSPDPVLGSVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYS 410
+ G S S+ + G P Y
Sbjct: 517 TGEKAYKCNECGKTFSWKSSL-TCHRRLHSGEKP------------------------YK 551
Query: 411 CPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYP 470
C C K FN L+ H + + P + C+ + NL H +K+H
Sbjct: 552 CKECGK-TFNQQLTLKRHRRLHSGENP---YKCEDSDKAYSFKSNLEIH-QKIHTEE--- 603
Query: 471 VMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTES 530
+ + CN C + F+ +SL H R+ G + C +C F +S
Sbjct: 604 -------NPYKCNECGKTFSRTSSLTCHRRL---------HTGEKPYKCEECDKAFRVKS 647
Query: 531 SLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKN 590
+L H ++ H E P Y C C + + K+
Sbjct: 648 NLEGH-RRIHTG------EKP-----------YKCNECGKT--------------FSRKS 675
Query: 591 IPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSISNGE--YPCNQCDLKFSNFESFQ 648
+ H + E+ ++ + ++ L + + GE Y CN+C FS +
Sbjct: 676 YFICHHRLHTGEKPYKCNECGKNFSQKSSLICH-HRLHTGEKPYKCNECGKTFSQKSNLT 734
Query: 649 THLKLH 654
H +LH
Sbjct: 735 CHRRLH 740
Score = 143 bits (360), Expect = 1e-33
Identities = 156/631 (24%), Positives = 221/631 (35%), Gaps = 124/631 (19%)
Query: 632 YPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTH 691
+ CN+ F+ + H +HL K C C + F+ + +L H H T
Sbjct: 215 FQCNESGKAFNYSSLLRKHQIIHLA---DKYKCDVCGKLFNQKRNLACHRRCH--TGENP 269
Query: 692 YVCESCDKQFSSVDDLQKHLLDMHTFVL-YHCTLCQEVFDSKVSIQVHLAVKHSNEKKMY 750
Y C C K FS L H +HT Y C C + F K ++ H + E+K Y
Sbjct: 270 YKCNECGKTFSQTSSLTCHRR-LHTGEKPYKCEECDKAFHFKSILERHRIIH--TEEKPY 326
Query: 751 RCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHITTHS--KKYN 808
+C C FR+++ L +H L K +KC CG+TFS + L CH H+ K Y
Sbjct: 327 KCNECGKTFRQKSIL---TRHHRLHTGEKPYKCNECGKTFSHKSSLTCHHRLHTGEKPYK 383
Query: 809 CKFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEA 868
C C K F L H R G P K E D N E
Sbjct: 384 CNECGKTFSHKSSLTCHRR-------------LHTGEKPY---KCEECDKAYSFRSNFEI 427
Query: 869 PNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKG 928
+ + Y C+ CG ++ L HR R +P
Sbjct: 428 HRK-------IHTEDNAYKCNECGKTFSRTSSLTCHRRRHTGEQP--------------- 465
Query: 929 SHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTG 988
+KC C + F ++ L H + H G K Y C CG+ F LT H H+
Sbjct: 466 -YKCEECDKAFRFKSNLERHRRIHTGE-KPYKCNECGKTFSRKSYLTCHHRLHTGE-KAY 522
Query: 989 TCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHM----Q 1044
C C + H ++H + ++C C +T L LK H H
Sbjct: 523 KCNECGKTFSWKSSLTCHRRLHSGEKP----YKCKECGKTFNQQLTLKRHRRLHSGENPY 578
Query: 1045 KLAGSSAASS--PNGQGLQKL------YKCALCLKEFRSKQDLVKLDVNGLPYGLCAGCM 1096
K S A S N + QK+ YKC C K F L C
Sbjct: 579 KCEDSDKAYSFKSNLEIHQKIHTEENPYKCNECGKTFSRTSSLT--------------CH 624
Query: 1097 ARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGPRKG 1156
R G+ +P +C EC F +LE H ++ +
Sbjct: 625 RRLHTGE-----------KP---YKCEECDKAFRVKSNLEGHRRIHTGE----------- 659
Query: 1157 TQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCH 1216
K Y+C +C TF + H H E+ ++C C + F + L+CH
Sbjct: 660 ---------KPYKCNECGKTFSRKSYFICHHRLHTGEKP--YKCNECGKNFSQKSSLICH 708
Query: 1217 LIEHSFEGMGGTFKCPVCFTVFVQANKLQQH 1247
H+ E +KC C F Q + L H
Sbjct: 709 HRLHTGE---KPYKCNECGKTFSQKSNLTCH 736
Score = 141 bits (355), Expect = 5e-33
Identities = 145/592 (24%), Positives = 217/592 (36%), Gaps = 122/592 (20%)
Query: 480 FHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQA 539
+ C+ C ++F +L H R G N + CN+C F SSLT H ++
Sbjct: 242 YKCDVCGKLFNQKRNLACHRRCH---------TGENPYKCNECGKTFSQTSSLTCH-RRL 291
Query: 540 HCSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKS 599
H E P Y C C + F SIL E H+ I
Sbjct: 292 HTG------EKP-----------YKCEECDKAFHFKSIL-------ERHRII-------- 319
Query: 600 KAEQSPVSSDVEVSSPKRQRLSASANSISNGE--YPCNQCDLKFSNFESFQTHLKLHLEL 657
E+ P + + +++ + + + GE Y CN+C FS+ S H +LH
Sbjct: 320 HTEEKPYKCNECGKTFRQKSILTRHHRLHTGEKPYKCNECGKTFSHKSSLTCHHRLHTGE 379
Query: 658 LLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTF 717
+ C +C + F + SL H +H T Y CE CDK +S + + H
Sbjct: 380 --KPYKCNECGKTFSHKSSLTCHRRLH--TGEKPYKCEECDKAYSFRSNFEIHRKIHTED 435
Query: 718 VLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVK------- 770
Y C C + F S+ H +H+ E+ Y+C C+ FR +++L+ H +
Sbjct: 436 NAYKCNECGKTFSRTSSLTCHRR-RHTGEQP-YKCEECDKAFRFKSNLERHRRIHTGEKP 493
Query: 771 ------------------HSHLGNPAKAHKCIFCGETFSTEVELQCHITTHS--KKYNCK 810
H L KA+KC CG+TFS + L CH HS K Y CK
Sbjct: 494 YKCNECGKTFSRKSYLTCHHRLHTGEKAYKCNECGKTFSWKSSLTCHRRLHSGEKPYKCK 553
Query: 811 FCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAPN 870
C K F+ + L++H R +G P K E +D N E
Sbjct: 554 ECGKTFNQQLTLKRHRR-------------LHSGENPY---KCEDSDKAYSFKSNLEI-- 595
Query: 871 SHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSH 930
+ E Y C+ CG ++ L HR + GE +
Sbjct: 596 -----HQKIHTEENPYKCNECGKTFSRTSSLTCHR----RLHTGEK------------PY 634
Query: 931 KCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTC 990
KC C + F ++ L H + H G K Y C CG+ F H H+ C
Sbjct: 635 KCEECDKAFRVKSNLEGHRRIHTG-EKPYKCNECGKTFSRKSYFICHHRLHTGE-KPYKC 692
Query: 991 RICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFH 1042
C + I H ++H + ++C C +T + L H H
Sbjct: 693 NECGKNFSQKSSLICHHRLHTGEK----PYKCNECGKTFSQKSNLTCHRRLH 740
Score = 128 bits (321), Expect = 4e-29
Identities = 80/290 (27%), Positives = 131/290 (45%), Gaps = 48/290 (16%)
Query: 64 ESIYTCDHCQQDFESLADLTDH-------RAHRCPGDGDDDPQLSWVASSPSSKDVASPT 116
E Y C+ C + F + LT H +A++C G SW +S + + S
Sbjct: 491 EKPYKCNECGKTFSRKSYLTCHHRLHTGEKAYKCNECGKT---FSWKSSLTCHRRLHS-- 545
Query: 117 QMIGDGCDLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFK 176
GE+ PY C+ C K+F + LKRH ++HS + P+KC + +
Sbjct: 546 -----------GEK------PYKCKECGKTFNQQLTLKRHRRLHSGENPYKCEDSDKAYS 588
Query: 177 HKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSS 236
K + + H K+HT + Y C+EC FSR+ L H + H+ KP+KC C + F S+
Sbjct: 589 FKSNLEIHQKIHTEENPYKCNECGKTFSRTSSLTCHRRLHTGEKPYKCEECDKAFRVKSN 648
Query: 237 LQSHMQAHKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQ 296
L+ H + H K + C+ C TFS+ + + + H + + +
Sbjct: 649 LEGHRRIHTGEKP-------------YKCNECGKTFSR----KSYFICHHRLHTGEKPYK 691
Query: 297 CIHCPEVFVDENTLLAHIHQAHANQK-HKCPMCPEQFSSVEGVYCHLDSH 345
C C + F +++L+ H H+ H +K +KC C + FS + CH H
Sbjct: 692 CNECGKNFSQKSSLICH-HRLHTGEKPYKCNECGKTFSQKSNLTCHRRLH 740
Score = 119 bits (299), Expect = 1e-26
Identities = 126/525 (24%), Positives = 197/525 (37%), Gaps = 112/525 (21%)
Query: 33 ECDQKTS-RALEDRNSVTSQEER----NEDDEDMEDESI-------------YTCDHCQQ 74
ECD+ +++ +R+ + EE+ NE + +SI Y C+ C +
Sbjct: 302 ECDKAFHFKSILERHRIIHTEEKPYKCNECGKTFRQKSILTRHHRLHTGEKPYKCNECGK 361
Query: 75 DFESLADLT-DHRAHRCPGDGDDDPQLSWVASSPSSKDVASPTQMIGDGCDLGLGEEEGG 133
F + LT HR H G+ + + + S K + + L GE+
Sbjct: 362 TFSHKSSLTCHHRLHT----GEKPYKCNECGKTFSHKSSLTCHRR------LHTGEK--- 408
Query: 134 TGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKK 193
PY C+ CDK++ S + H +IH++ +KC C + F S H + HTG++
Sbjct: 409 ---PYKCEECDKAYSFRSNFEIHRKIHTEDNAYKCNECGKTFSRTSSLTCHRRRHTGEQP 465
Query: 194 YHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAK 253
Y C EC+ AF +L+ H + H+ KP+KC C + FS S L H + H K
Sbjct: 466 YKCEECDKAFRFKSNLERHRRIHTGEKPYKCNECGKTFSRKSYLTCHHRLHTGEKA---- 521
Query: 254 SEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQL-SEKADLQCIHCPEVFVDENTLLA 312
+ C+ C TFS K LT H +L S + +C C + F + TL
Sbjct: 522 ---------YKCNECGKTFSW-----KSSLTCHRRLHSGEKPYKCKECGKTFNQQLTLKR 567
Query: 313 HIHQAHANQKHKCPMCPEQFSSVEGVYCHLDSHRQ--PDSSNHSVSPDPVLGSVASMSSA 370
H +KC + +S + H H + P N G S +S+
Sbjct: 568 HRRLHSGENPYKCEDSDKAYSFKSNLEIHQKIHTEENPYKCNE-------CGKTFSRTSS 620
Query: 371 TPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLK 430
+ G P Y C C K F + LE H +
Sbjct: 621 L-TCHRRLHTGEKP------------------------YKCEECDKA-FRVKSNLEGHRR 654
Query: 431 TIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFA 490
+KP + + C Y + H +LH + CN C + F+
Sbjct: 655 IHTGEKPYKCNECGKTFSRKS--YFICHH--RLHTGE----------KPYKCNECGKNFS 700
Query: 491 DINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEH 535
+SL H R+ G + CN+C F +S+LT H
Sbjct: 701 QKSSLICHHRL---------HTGEKPYKCNECGKTFSQKSNLTCH 736
Score = 119 bits (298), Expect = 2e-26
Identities = 151/663 (22%), Positives = 236/663 (35%), Gaps = 140/663 (21%)
Query: 296 QCIHCPEVFVDENTLLAHIHQAHANQKHKCPMCPEQFSSVEGVYCHLDSH--RQPDSSNH 353
QC + F + ++LL H K+KC +C + F+ + CH H P N
Sbjct: 216 QCNESGKAF-NYSSLLRKHQIIHLADKYKCDVCGKLFNQKRNLACHRRCHTGENPYKCNE 274
Query: 354 SVSPDPVLGSVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPY 413
G S +S+ + G P Y C
Sbjct: 275 C-------GKTFSQTSSLT-CHRRLHTGEKP------------------------YKCEE 302
Query: 414 CSKRDFNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQ 473
C K F+ ++LE H + IH + ++ + C C + L H R LH
Sbjct: 303 CDKA-FHFKSILERH-RIIHTE--EKPYKCNECGKTFRQKSILTRHHR-LHTGE------ 351
Query: 474 FGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLT 533
+ CN C + F+ +SL H R+ G + CN+C F +SSLT
Sbjct: 352 ----KPYKCNECGKTFSHKSSLTCHHRLH---------TGEKPYKCNECGKTFSHKSSLT 398
Query: 534 EHIQQAHCSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPL 593
H ++ H E P Y C C + F S ++ + I
Sbjct: 399 CH-RRLHTG------EKP-----------YKCEECDKAYSFRSNFEIHRKIHTEDNAYKC 440
Query: 594 AHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKL 653
K+ + S ++ R+R + Y C +CD F + + H ++
Sbjct: 441 NECGKTFSRTSSLTCH-------RRRHTGEQ------PYKCEECDKAFRFKSNLERHRRI 487
Query: 654 HLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLD 713
H + C +C + F + L H +H T Y C C K FS L H
Sbjct: 488 HTGE--KPYKCNECGKTFSRKSYLTCHHRLH--TGEKAYKCNECGKTFSWKSSLTCHRRL 543
Query: 714 MHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSH 773
Y C C + F+ +++++ H + HS E Y+C + + +++L++H K
Sbjct: 544 HSGEKPYKCKECGKTFNQQLTLKRHRRL-HSGENP-YKCEDSDKAYSFKSNLEIHQKIHT 601
Query: 774 LGNPAKAHKCIFCGETFSTEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHLREKHC 831
NP +KC CG+TFS L CH H+ K Y C+ C KAF LE H R
Sbjct: 602 EENP---YKCNECGKTFSRTSSLTCHRRLHTGEKPYKCEECDKAFRVKSNLEGHRR---- 654
Query: 832 VFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDIC 891
G P + + S+ + E Y C+ C
Sbjct: 655 ---------IHTGEKPYKCNECGKTFSR----------KSYFICHHRLHTGEKPYKCNEC 695
Query: 892 GAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQT 951
G ++ + L H H + GE +KCN C +TF ++ L H +
Sbjct: 696 GKNFSQKSSLICH----HRLHTGEKP------------YKCNECGKTFSQKSNLTCHRRL 739
Query: 952 HRG 954
H G
Sbjct: 740 HTG 742
Score = 113 bits (283), Expect = 1e-24
Identities = 128/549 (23%), Positives = 196/549 (35%), Gaps = 140/549 (25%)
Query: 737 VHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLG-NPAKAHKCIFCGETFSTEVE 795
+HLA K Y+C C F ++ +L H + H G NP +KC CG+TFS
Sbjct: 236 IHLADK-------YKCDVCGKLFNQKRNLACH-RRCHTGENP---YKCNECGKTFSQTSS 284
Query: 796 LQCHITTHS--KKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKA 853
L CH H+ K Y C+ C KAFH K + E+H +
Sbjct: 285 LTCHRRLHTGEKPYKCEECDKAFHF-----KSILERHRI--------------------- 318
Query: 854 EPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRP 913
+ E Y C+ CG + + +L H H +
Sbjct: 319 -------------------------IHTEEKPYKCNECGKTFRQKSILTRH----HRLHT 349
Query: 914 GEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLT 973
GE +KCN C +TF ++ L H + H G K Y C CG+ F +
Sbjct: 350 GEKP------------YKCNECGKTFSHKSSLTCHHRLHTGE-KPYKCNECGKTFSHKSS 396
Query: 974 LTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTL 1033
LT H+ H+ C C F H ++H + ++C C +T + T
Sbjct: 397 LTCHRRLHTGEKPY-KCEECDKAYSFRSNFEIHRKIHTEDN----AYKCNECGKTFSRTS 451
Query: 1034 ELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLVK---LDVNGLPYG 1090
L H H ++ YKC C K FR K +L + + PY
Sbjct: 452 SLTCHRRRHTG----------------EQPYKCEECDKAFRFKSNLERHRRIHTGEKPYK 495
Query: 1091 L--CAGCMARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTP 1148
C +R + L +C EC F L H ++
Sbjct: 496 CNECGKTFSRKSY-----LTCHHRLHTGEKAYKCNECGKTFSWKSSLTCHRRLH------ 544
Query: 1149 ETSGPRKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFD 1208
SG +K Y+C +C TF + ++ H H E ++C+ ++ +
Sbjct: 545 --SG------------EKPYKCKECGKTFNQQLTLKRHRRLHSGENP--YKCEDSDKAYS 588
Query: 1209 SPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKF 1268
+ L H H+ E +KC C F + + L H G+ K Y C +C + F
Sbjct: 589 FKSNLEIHQKIHTEEN---PYKCNECGKTFSRTSSLTCHRRLHTGE--KPYKCEECDKAF 643
Query: 1269 FFQTELQNH 1277
++ L+ H
Sbjct: 644 RVKSNLEGH 652
Score = 106 bits (265), Expect = 1e-22
Identities = 57/186 (30%), Positives = 88/186 (47%), Gaps = 18/186 (9%)
Query: 137 PYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 196
PY C+ DK++ S L+ H++IH+++ P+KC C + F S H +LHTG+K Y C
Sbjct: 577 PYKCEDSDKAYSFKSNLEIHQKIHTEENPYKCNECGKTFSRTSSLTCHRRLHTGEKPYKC 636
Query: 197 HECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEK 256
EC+ AF +L+ H + H+ KP+KC C + FS S H + H K
Sbjct: 637 EECDKAFRVKSNLEGHRRIHTGEKPYKCNECGKTFSRKSYFICHHRLHTGEK-------- 688
Query: 257 EAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQ 316
+ C+ C FSQ L H H + + +C C + F ++ L H +
Sbjct: 689 -----PYKCNECGKNFSQKSSLICH----HRLHTGEKPYKCNECGKTFSQKSNLTCH-RR 738
Query: 317 AHANQK 322
H +K
Sbjct: 739 LHTGEK 744
Score = 101 bits (251), Expect = 5e-21
Identities = 45/113 (39%), Positives = 64/113 (56%)
Query: 137 PYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 196
PY C+ CDK+F S L+ H +IH+ + P+KC C + F K H +LHTG+K Y C
Sbjct: 633 PYKCEECDKAFRVKSNLEGHRRIHTGEKPYKCNECGKTFSRKSYFICHHRLHTGEKPYKC 692
Query: 197 HECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKE 249
+EC FS+ L H + H+ KP+KC C + FS S+L H + H K+
Sbjct: 693 NECGKNFSQKSSLICHHRLHTGEKPYKCNECGKTFSQKSNLTCHRRLHTGEKQ 745
Score = 68.6 bits (166), Expect = 4e-11
Identities = 76/352 (21%), Positives = 121/352 (34%), Gaps = 84/352 (23%)
Query: 929 SHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTG 988
S +CN + F + LR+H H A Y C +CG+ F L H+ H+ +
Sbjct: 214 SFQCNESGKAFNYSSLLRKHQIIHL--ADKYKCDVCGKLFNQKRNLACHRRCHTGE-NPY 270
Query: 989 TCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAG 1048
C C H ++H + ++C C + L+ H H +
Sbjct: 271 KCNECGKTFSQTSSLTCHRRLHTGEKP----YKCEECDKAFHFKSILERHRIIHTE---- 322
Query: 1049 SSAASSPNGQGLQKLYKCALCLKEFRSKQDLVK---LDVNGLPYGLCAGCMARSANGQVG 1105
+K YKC C K FR K L + L PY
Sbjct: 323 ------------EKPYKCNECGKTFRQKSILTRHHRLHTGEKPY---------------- 354
Query: 1106 GLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGPRKGTQTSPVPRK 1165
+C EC F L H HR T E
Sbjct: 355 ---------------KCNECGKTFSHKSSLTCH----HRLHTGE---------------- 379
Query: 1166 KTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGM 1225
K Y+C +C TF ++ + H H E+ ++C+ C++ + + H H+ +
Sbjct: 380 KPYKCNECGKTFSHKSSLTCHRRLHTGEKP--YKCEECDKAYSFRSNFEIHRKIHTEDN- 436
Query: 1226 GGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNH 1277
+KC C F + + L H G++ Y C +C + F F++ L+ H
Sbjct: 437 --AYKCNECGKTFSRTSSLTCHRRRHTGEQP--YKCEECDKAFRFKSNLERH 484
Score = 54.3 bits (129), Expect = 7e-07
Identities = 31/114 (27%), Positives = 55/114 (48%), Gaps = 8/114 (7%)
Query: 1164 RKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFE 1223
R+K++QC + F ++ H H+ ++ ++C +C ++F+ L CH H+ E
Sbjct: 211 REKSFQCNESGKAFNYSSLLRKHQIIHLADK---YKCDVCGKLFNQKRNLACHRRCHTGE 267
Query: 1224 GMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNH 1277
+KC C F Q + L H G+ K Y C +C + F F++ L+ H
Sbjct: 268 N---PYKCNECGKTFSQTSSLTCHRRLHTGE--KPYKCEECDKAFHFKSILERH 316
>gi|23308729 zinc finger protein 268 [Homo sapiens]
Length = 947
Score = 187 bits (476), Expect = 4e-47
Identities = 203/867 (23%), Positives = 317/867 (36%), Gaps = 184/867 (21%)
Query: 100 LSWVASSPSSKDVASPTQMIGDGCDLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQI 159
+ + S S K V +Q++ + +GE+ P+ C C+K+F SYL H+Q
Sbjct: 246 IKYCESIESGKTVNKKSQLMCQ--QMYMGEK------PFGCSCCEKAFSSKSYLLVHQQT 297
Query: 160 HSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSS 219
H+++ P+ C C + F K H ++HTG+K + C EC FS L IH + H+
Sbjct: 298 HAEEKPYGCNECGKDFSSKSYLIVHQRIHTGEKLHECSECRKTFSFHSQLVIHQRIHTGE 357
Query: 220 KPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELE 279
P++C C + FS L SH + H K ++C+ C F +L
Sbjct: 358 NPYECCECGKVFSRKDQLVSHQKTHSGQK-------------PYVCNECGKAFGLKSQL- 403
Query: 280 KHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQAHANQKHKCPMCPEQFSSVEGVY 339
++ EK +C C + F ++ L+ H + + C C + F+ +
Sbjct: 404 --IIHERIHTGEK-PYECNECQKAFNTKSNLMVHQRTHTGEKPYVCSDCGKAFTFKSQLI 460
Query: 340 CHLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRD 399
H H V P G + + S V + S + +KP
Sbjct: 461 VHQGIHT-------GVKP---YGCIQCGKGFSLKSQLIVHQRS--HTGMKP--------- 499
Query: 400 DGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEH 459
Y C C K F S + L IH +T +K H C C + L H
Sbjct: 500 ---------YVCNECGKA-FRSKSYLIIHTRTHTGEK---LHECNNCGKAFSFKSQLIIH 546
Query: 460 VRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFC 519
+++H + + C+ C + F+ L H R +H G + C
Sbjct: 547 -QRIHTGE----------NPYECHECGKAFSRKYQLISHQR-THA--------GEKPYEC 586
Query: 520 NQCSMGFLTESSLTEHIQQAH-------CS----VGSAKLESPVVQPTQSFMEVYSCPYC 568
C F +S L H Q+ H CS + K V Q T + + YSC C
Sbjct: 587 TDCGKAFGLKSQLIIH-QRTHTGEKPFECSECQKAFNTKSNLIVHQRTHTGEKPYSCNEC 645
Query: 569 TNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSIS 628
+ F S L + K + K P S+ +K S K Q + +
Sbjct: 646 GKAFTFKSQLIVHKGVHTGVK--PYGCSQCAK-----------TFSLKSQLIVHQRSHTG 692
Query: 629 NGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTT 688
Y C++C F + H++ H + C +C + F L+ H +H T
Sbjct: 693 VKPYGCSECGKAFRSKSYLIIHMRTHTG--EKPHECRECGKSFSFNSQLIVHQRIH--TG 748
Query: 689 STHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKK 748
Y C C K F+ D L H Y C+ C + F SK + +H+ HS EK
Sbjct: 749 ENPYECSECGKAFNRKDQLISHQRTHAGEKPYGCSECGKAFSSKSYLIIHMRT-HSGEKP 807
Query: 749 MYRCTACNWDFRKEADLQVHVKHSHLG-NPAKAHKCIFCGETFSTEVELQCH--ITTHSK 805
Y C C F ++ L VH + +H G NP +KC C ++FS ++ L H + T K
Sbjct: 808 -YECNECGKAFIWKSLLIVH-ERTHAGVNP---YKCSQCEKSFSGKLRLLVHQRMHTREK 862
Query: 806 KYNCKFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKN 865
Y C C KAF +R + T +G
Sbjct: 863 PYECSECGKAF---------IRNSQLIVHQRTHSG------------------------- 888
Query: 866 PEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEF 925
E YGC+ CG ++ + +L H+ +P
Sbjct: 889 -----------------EKPYGCNECGKTFSQKSILSAHQRTHTGEKP------------ 919
Query: 926 IKGSHKCNVCSRTFFSENGLREHLQTH 952
KC C + F ++ L H +TH
Sbjct: 920 ----CKCTECGKAFCWKSQLIMHQRTH 942
Score = 168 bits (425), Expect = 3e-41
Identities = 184/779 (23%), Positives = 287/779 (36%), Gaps = 172/779 (22%)
Query: 64 ESIYTCDHCQQDFESLADLTDH-RAHRCPGDGDDDPQLSWVASSPSSKDVASPTQMIGDG 122
E ++ C C++ F + L H R H G++ + S KD Q G
Sbjct: 329 EKLHECSECRKTFSFHSQLVIHQRIHT----GENPYECCECGKVFSRKDQLVSHQKTHSG 384
Query: 123 CDLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRD 182
PY C C K+F S L HE+IH+ + P++C C + F K +
Sbjct: 385 QK------------PYVCNECGKAFGLKSQLIIHERIHTGEKPYECNECQKAFNTKSNLM 432
Query: 183 RHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQ 242
H + HTG+K Y C +C AF+ L +H H+ KP+ C C +GFS S L H +
Sbjct: 433 VHQRTHTGEKPYVCSDCGKAFTFKSQLIVHQGIHTGVKPYGCIQCGKGFSLKSQLIVHQR 492
Query: 243 AHKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPE 302
+H K ++C+ C F L H T EK +C +C +
Sbjct: 493 SHTGMK-------------PYVCNECGKAFRSKSYLIIHTRT---HTGEKLH-ECNNCGK 535
Query: 303 VFVDENTLLAHIHQAHANQKHKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLG 362
F ++ L+ H ++C C + FS + H +H P
Sbjct: 536 AFSFKSQLIIHQRIHTGENPYECHECGKAFSRKYQLISHQRTH---------AGEKPYEC 586
Query: 363 SVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSL 422
+ + +R T + KP + C C K FN+
Sbjct: 587 TDCGKAFGLKSQLIIHQRTHTGE---KP------------------FECSECQKA-FNTK 624
Query: 423 AVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHC 482
+ L +H +T +KP + C L +HK V +G C
Sbjct: 625 SNLIVHQRTHTGEKPYSCNECGKAFTFKSQLI--------VHKGVHTGVKPYG------C 670
Query: 483 NYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCS 542
+ C + F+ + L H R SH G + C++C F ++S L H++
Sbjct: 671 SQCAKTFSLKSQLIVHQR-SHTGV--------KPYGCSECGKAFRSKSYLIIHMR----- 716
Query: 543 VGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAE 602
T + + + C C S F S L + H
Sbjct: 717 -------------THTGEKPHECRECGKSFSFNSQL--------------IVH------- 742
Query: 603 QSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQ 662
QR+ N Y C++C F+ + +H + H +
Sbjct: 743 ---------------QRIHTGEN-----PYECSECGKAFNRKDQLISHQRTHAG--EKPY 780
Query: 663 ACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFV---- 718
C +C + F S+ L+ H+ H + Y C C K F + K LL +H
Sbjct: 781 GCSECGKAFSSKSYLIIHMRTH--SGEKPYECNECGKAF-----IWKSLLIVHERTHAGV 833
Query: 719 -LYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNP 777
Y C+ C++ F K+ + VH + H+ EK Y C+ C F + + L VH + +H G
Sbjct: 834 NPYKCSQCEKSFSGKLRLLVHQRM-HTREKP-YECSECGKAFIRNSQLIVH-QRTHSGE- 889
Query: 778 AKAHKCIFCGETFSTEVELQCHITTHS--KKYNCKFCSKAF----HAIILLEKHLREKH 830
K + C CG+TFS + L H TH+ K C C KAF I+ H+ +KH
Sbjct: 890 -KPYGCNECGKTFSQKSILSAHQRTHTGEKPCKCTECGKAFCWKSQLIMHQRTHVDDKH 947
Score = 150 bits (378), Expect = 1e-35
Identities = 162/664 (24%), Positives = 250/664 (37%), Gaps = 103/664 (15%)
Query: 632 YPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTH 691
Y CN+C FS+ H ++H L + C +C++ F L+ H +H T
Sbjct: 304 YGCNECGKDFSSKSYLIVHQRIHTGEKLHE--CSECRKTFSFHSQLVIHQRIH--TGENP 359
Query: 692 YVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYR 751
Y C C K FS D L H Y C C + F K + +H + H+ EK Y
Sbjct: 360 YECCECGKVFSRKDQLVSHQKTHSGQKPYVCNECGKAFGLKSQLIIHERI-HTGEKP-YE 417
Query: 752 CTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHITTHS--KKYNC 809
C C F +++L VH + +H G K + C CG+ F+ + +L H H+ K Y C
Sbjct: 418 CNECQKAFNTKSNLMVH-QRTHTGE--KPYVCSDCGKAFTFKSQLIVHQGIHTGVKPYGC 474
Query: 810 KFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAP 869
C K F L H R G+ P + A
Sbjct: 475 IQCGKGFSLKSQLIVHQRSH-------------TGMKPYVCNECGKAFRS---------- 511
Query: 870 NSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGS 929
S+ E ++ C+ CG A++ + L H+ I GE+
Sbjct: 512 KSYLIIHTRTHTGEKLHECNNCGKAFSFKSQLIIHQ----RIHTGENP------------ 555
Query: 930 HKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGT 989
++C+ C + F + L H +TH G K Y C CG+ F L H+ TH+
Sbjct: 556 YECHECGKAFSRKYQLISHQRTHAGE-KPYECTDCGKAFGLKSQLIIHQRTHTGEKPF-E 613
Query: 990 CRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQ-KLAG 1048
C C+ ++ I H + H + + C C + T +L +H H K G
Sbjct: 614 CSECQKAFNTKSNLIVHQRTHTGEKP----YSCNECGKAFTFKSQLIVHKGVHTGVKPYG 669
Query: 1049 SSAASSPNGQGLQ-----------KLYKCALCLKEFRSKQDLV---KLDVNGLPYGLCAG 1094
S + Q K Y C+ C K FRSK L+ + P+ C
Sbjct: 670 CSQCAKTFSLKSQLIVHQRSHTGVKPYGCSECGKAFRSKSYLIIHMRTHTGEKPHE-CRE 728
Query: 1095 C-MARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGP 1153
C + S N Q+ + P C EC F + L SH + +
Sbjct: 729 CGKSFSFNSQLIVHQRIHTGENP---YECSECGKAFNRKDQLISHQRTHAGE-------- 777
Query: 1154 RKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKL 1213
K Y C +C F ++ + IH+ H E+ +EC C + F + L
Sbjct: 778 ------------KPYGCSECGKAFSSKSYLIIHMRTHSGEKP--YECNECGKAFIWKSLL 823
Query: 1214 LCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTE 1273
+ H E + G+ +KC C F + KL+ + +K Y+CS+C + F ++
Sbjct: 824 IVH--ERTHAGVN-PYKCSQCEKSF--SGKLRLLVHQRMHTREKPYECSECGKAFIRNSQ 878
Query: 1274 LQNH 1277
L H
Sbjct: 879 LIVH 882
Score = 144 bits (363), Expect = 5e-34
Identities = 179/786 (22%), Positives = 286/786 (36%), Gaps = 146/786 (18%)
Query: 578 LKLTKHIKENHKNIPLAHSKK---SKAEQSPVS----SDVEVSSPKRQRLSASANSISNG 630
+ T N+ N H K SK EQ+ + +E ++ + G
Sbjct: 213 IDFTSDYARNNPNGFQVHGKSFFHSKHEQTVIGIKYCESIESGKTVNKKSQLMCQQMYMG 272
Query: 631 EYP--CNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVH---- 684
E P C+ C+ FS+ H + H E + C +C +DF S+ L+ H +H
Sbjct: 273 EKPFGCSCCEKAFSSKSYLLVHQQTHAE--EKPYGCNECGKDFSSKSYLIVHQRIHTGEK 330
Query: 685 -------YMTTSTH---------------YVCESCDKQFSSVDDLQKHLLDMHTFVLYHC 722
T S H Y C C K FS D L H Y C
Sbjct: 331 LHECSECRKTFSFHSQLVIHQRIHTGENPYECCECGKVFSRKDQLVSHQKTHSGQKPYVC 390
Query: 723 TLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVH-------------- 768
C + F K + +H + H+ EK Y C C F +++L VH
Sbjct: 391 NECGKAFGLKSQLIIHERI-HTGEKP-YECNECQKAFNTKSNLMVHQRTHTGEKPYVCSD 448
Query: 769 -----------VKHSHLGNPAKAHKCIFCGETFSTEVELQCHITTHS--KKYNCKFCSKA 815
+ H + K + CI CG+ FS + +L H +H+ K Y C C KA
Sbjct: 449 CGKAFTFKSQLIVHQGIHTGVKPYGCIQCGKGFSLKSQLIVHQRSHTGMKPYVCNECGKA 508
Query: 816 FHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAPNSHEAS 875
F + L H R T G +K + G H+
Sbjct: 509 FRSKSYLIIHTR---------THTG----------EKLHECNNCGKAFSFKSQLIIHQR- 548
Query: 876 EDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRP------GEDDGSRKKAEFIKGS 929
+ E Y C CG A++ + L +H+ +P G+ G + + + +
Sbjct: 549 ---IHTGENPYECHECGKAFSRKYQLISHQRTHAGEKPYECTDCGKAFGLKSQLIIHQRT 605
Query: 930 H------KCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSK 983
H +C+ C + F +++ L H +TH G K Y C CG+ F L HK H+
Sbjct: 606 HTGEKPFECSECQKAFNTKSNLIVHQRTHTG-EKPYSCNECGKAFTFKSQLIVHKGVHTG 664
Query: 984 SLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHM 1043
G C C + + I H + H ++ + C C + S L IH H
Sbjct: 665 VKPYG-CSQCAKTFSLKSQLIVHQRSHTGVK----PYGCSECGKAFRSKSYLIIHMRTHT 719
Query: 1044 QKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLV---KLDVNGLPYGLCAGC-MARS 1099
+K ++C C K F L+ ++ PY C+ C A +
Sbjct: 720 G----------------EKPHECRECGKSFSFNSQLIVHQRIHTGENPYE-CSECGKAFN 762
Query: 1100 ANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGPRKG--T 1157
Q+ ++P C EC F S L HM+ + E + K
Sbjct: 763 RKDQLISHQRTHAGEKPYG---CSECGKAFSSKSYLIIHMRTHSGEKPYECNECGKAFIW 819
Query: 1158 QTSPVPRKKT------YQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPA 1211
++ + ++T Y+C +C+ +F + + +H H E+ +EC C + F +
Sbjct: 820 KSLLIVHERTHAGVNPYKCSQCEKSFSGKLRLLVHQRMHTREK--PYECSECGKAFIRNS 877
Query: 1212 KLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQ 1271
+L+ H HS E G C C F Q + L H G +K C++C + F ++
Sbjct: 878 QLIVHQRTHSGEKPYG---CNECGKTFSQKSILSAHQRTHTG--EKPCKCTECGKAFCWK 932
Query: 1272 TELQNH 1277
++L H
Sbjct: 933 SQLIMH 938
Score = 136 bits (343), Expect = 1e-31
Identities = 175/766 (22%), Positives = 267/766 (34%), Gaps = 135/766 (17%)
Query: 409 YSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHA 468
+ C C K F+S + L +H +T +KP + C S L +++ + K H
Sbjct: 276 FGCSCCEKA-FSSKSYLLVHQQTHAEEKPYGCNECGKDFSSKSYLI-VHQRIHTGEKLH- 332
Query: 469 YPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLT 528
C+ C + F+ + L H R+ G N + C +C F
Sbjct: 333 ------------ECSECRKTFSFHSQLVIHQRIH---------TGENPYECCECGKVFSR 371
Query: 529 ESSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENH 588
+ L H Q T S + Y C C + FG +L H + +
Sbjct: 372 KDQLVSH------------------QKTHSGQKPYVCNECGKA--FGLKSQLIIHERIHT 411
Query: 589 KNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQ 648
P ++ KA + K + Y C+ C F+
Sbjct: 412 GEKPYECNECQKAFNT-----------KSNLMVHQRTHTGEKPYVCSDCGKAFTFKSQLI 460
Query: 649 THLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQ 708
H +H + + C QC + F + L+ H H T YVC C K F S L
Sbjct: 461 VHQGIHTGV--KPYGCIQCGKGFSLKSQLIVHQRSH--TGMKPYVCNECGKAFRSKSYLI 516
Query: 709 KHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVH 768
H L+ C C + F K + +H + H+ E Y C C F ++ L H
Sbjct: 517 IHTRTHTGEKLHECNNCGKAFSFKSQLIIHQRI-HTGENP-YECHECGKAFSRKYQLISH 574
Query: 769 VKHSHLGNPAKAHKCIFCGETFSTEVELQCHITTHS--KKYNCKFCSKAFHA----IILL 822
+ +H G K ++C CG+ F + +L H TH+ K + C C KAF+ I+
Sbjct: 575 -QRTHAGE--KPYECTDCGKAFGLKSQLIIHQRTHTGEKPFECSECQKAFNTKSNLIVHQ 631
Query: 823 EKHLREK-----HC------VFDAATENGTANGVPPMATKK-AEPADLQGMLLKNPEAPN 870
H EK C G GV P + A+ L+ L+
Sbjct: 632 RTHTGEKPYSCNECGKAFTFKSQLIVHKGVHTGVKPYGCSQCAKTFSLKSQLI------- 684
Query: 871 SHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFI---- 926
H+ S V YGC CG A+ + L H +P E K F
Sbjct: 685 VHQRSHTGVKP----YGCSECGKAFRSKSYLIIHMRTHTGEKPHECRECGKSFSFNSQLI 740
Query: 927 --------KGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHK 978
+ ++C+ C + F ++ L H +TH G K Y C CG+ F S L H
Sbjct: 741 VHQRIHTGENPYECSECGKAFNRKDQLISHQRTHAG-EKPYGCSECGKAFSSKSYLIIHM 799
Query: 979 VTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIH 1038
THS C C + I H + H + ++C C ++ + L L +H
Sbjct: 800 RTHSGE-KPYECNECGKAFIWKSLLIVHERTHA----GVNPYKCSQCEKSFSGKLRLLVH 854
Query: 1039 GTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLV---KLDVNGLPYGLCAGC 1095
H + +K Y+C+ C K F L+ + PYG C C
Sbjct: 855 QRMHTR----------------EKPYECSECGKAFIRNSQLIVHQRTHSGEKPYG-CNEC 897
Query: 1096 -MARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQ 1140
S + ++PC +C EC F L H +
Sbjct: 898 GKTFSQKSILSAHQRTHTGEKPC---KCTECGKAFCWKSQLIMHQR 940
Score = 109 bits (272), Expect = 2e-23
Identities = 132/566 (23%), Positives = 194/566 (34%), Gaps = 157/566 (27%)
Query: 720 YHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAK 779
+ C+ C++ F SK + VH H+ EK Y C C DF ++ L VH + H G K
Sbjct: 276 FGCSCCEKAFSSKSYLLVHQQT-HAEEKP-YGCNECGKDFSSKSYLIVH-QRIHTGE--K 330
Query: 780 AHKCIFCGETFSTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFDAAT 837
H+C C +TFS +L H I T Y C C K F L H +
Sbjct: 331 LHECSECRKTFSFHSQLVIHQRIHTGENPYECCECGKVFSRKDQLVSHQK---------- 380
Query: 838 ENGTANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTM 897
T +G P Y C+ CG A+ +
Sbjct: 381 ---THSGQKP--------------------------------------YVCNECGKAFGL 399
Query: 898 EVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAK 957
+ L H I GE ++CN C + F +++ L H +TH G K
Sbjct: 400 KSQLIIHE----RIHTGEKP------------YECNECQKAFNTKSNLMVHQRTHTGE-K 442
Query: 958 HYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSL 1017
Y+C CG+ F L H+ H+ G C C + + I H + H ++
Sbjct: 443 PYVCSDCGKAFTFKSQLIVHQGIHTGVKPYG-CIQCGKGFSLKSQLIVHQRSHTGMKP-- 499
Query: 1018 TGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQ 1077
+ C C + S L IH H +KL++C C K F K
Sbjct: 500 --YVCNECGKAFRSKSYLIIHTRTHTG----------------EKLHECNNCGKAFSFKS 541
Query: 1078 DLV---KLDVNGLPYGLCAGCMARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAED 1134
L+ ++ PY C EC F
Sbjct: 542 QLIIHQRIHTGENPY-------------------------------ECHECGKAFSRKYQ 570
Query: 1135 LESHMQVDHRDLTPETSGPRKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEE 1194
L SH + + K Y+C C F + ++ IH H E+
Sbjct: 571 LISHQRTHAGE--------------------KPYECTDCGKAFGLKSQLIIHQRTHTGEK 610
Query: 1195 GINHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQ 1254
EC C + F++ + L+ H H+ E + C C F ++L H G
Sbjct: 611 PF--ECSECQKAFNTKSNLIVHQRTHTGEK---PYSCNECGKAFTFKSQLIVHKGVHTGV 665
Query: 1255 EDKIYDCSQCPQKFFFQTELQNHTMS 1280
K Y CSQC + F +++L H S
Sbjct: 666 --KPYGCSQCAKTFSLKSQLIVHQRS 689
>gi|172072608 zinc finger protein 624 [Homo sapiens]
Length = 865
Score = 187 bits (474), Expect = 7e-47
Identities = 168/709 (23%), Positives = 265/709 (37%), Gaps = 119/709 (16%)
Query: 124 DLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDR 183
+L LG++ PY C C+K+F S L +H++ H+ + P++C C + F +
Sbjct: 262 ELTLGKKSNNKEKPYKCSTCEKAFHYRSLLIQHQRTHTKEKPYECNECGKTFSQPSYLSQ 321
Query: 184 HIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQA 243
H K+HTG+K Y C+EC AF S L +H + H+ KP++C VC + FS + L H +
Sbjct: 322 HKKIHTGEKPYKCNECGKAFIASSSLMVHQRIHTKEKPYQCNVCGKSFSQCARLNQHQRI 381
Query: 244 HKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEV 303
K + C C FS +L +H T + + K C C +
Sbjct: 382 QTGEK-------------PYKCSECGKAFSDKSKLARHQETHNGEKPYK----CDDCGKA 424
Query: 304 FVDENTLLAHIHQAHANQK-HKCPMCPEQF--SSVEGVYCHLDSHRQPDSSNHSVSPDPV 360
F +++ L H + H +K ++C C + F +++ V+ + + +P N
Sbjct: 425 FRNKSYLSVH-QKTHTEEKPYQCNECGKSFKNTTIFNVHQRIHTGEKPFRCNEC------ 477
Query: 361 LGSVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFN 420
A S+++ G P Y C C K FN
Sbjct: 478 --GKAYRSNSSLIVHIRTHTGEKP------------------------YECNECGKA-FN 510
Query: 421 SLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAF 480
+A H + +KP + C C + L H H+ H +
Sbjct: 511 RIANFTEHQRIHTGEKP---YKCNECGKAFINYSCLTVH----HRMHT-------GEKPY 556
Query: 481 HCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAH 540
C C + F +SL H R+ + CN+C F +S LT H Q+ H
Sbjct: 557 KCTECGKAFMRSSSLIIHQRI---------HTEEKPYLCNECGESFRIKSHLTVH-QRIH 606
Query: 541 CSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSK 600
E P Y C C + F ++ L +H K + P K
Sbjct: 607 TG------EKP-----------YKCTDCERA--FTKMVNLKEHQKIHTGVKPYKCYDCGK 647
Query: 601 AEQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLR 660
+ ++ K + Y CN+C+ F+N H + H +
Sbjct: 648 SFRT-----------KSYLIVHQRTHTGEKPYKCNECEKAFTNTSQLTVHQRRHTG--EK 694
Query: 661 KQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLY 720
C +C + F S H H T + C C K FS + + +H Y
Sbjct: 695 PYKCNECGKVFTSNSGFNTHQRTH--TGEKPFKCNDCGKAFSQMVHVTEHQKIHSGEKPY 752
Query: 721 HCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKA 780
C +C + F + VH H+ EK Y C C + L +H + H G +
Sbjct: 753 KCDVCGKAFRRGSYLTVHWRT-HTGEKP-YTCKECGKGCITLSQLTLH-QRIHTGE--RP 807
Query: 781 HKCIFCGETFSTEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHLR 827
+KC CG+ F T + H+ H+ K Y C C KAF + L H R
Sbjct: 808 YKCEECGKAFRTNSDFTVHLRMHTGEKPYKCNECGKAFRSSSSLTVHQR 856
Score = 182 bits (462), Expect = 2e-45
Identities = 162/690 (23%), Positives = 261/690 (37%), Gaps = 151/690 (21%)
Query: 145 KSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAFS 204
K+ + S L ++ ++ + P+KC+ C + F ++ +H + HT +K Y C+EC FS
Sbjct: 255 KAIRQTSELTLGKKSNNKEKPYKCSTCEKAFHYRSLLIQHQRTHTKEKPYECNECGKTFS 314
Query: 205 RSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEKEAKKDDFM 264
+ +L H K H+ KP+KC C + F ++SSL H + H K K +
Sbjct: 315 QPSYLSQHKKIHTGEKPYKCNECGKAFIASSSLMVHQRIHTKEK-------------PYQ 361
Query: 265 CDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQAHANQKHK 324
C+ C +FSQ L +H + Q EK +C C + F D++ L H + + +K
Sbjct: 362 CNVCGKSFSQCARLNQH---QRIQTGEK-PYKCSECGKAFSDKSKLARHQETHNGEKPYK 417
Query: 325 CPMCPEQFSSVEGVYCHLDSH--RQPDSSNHSVSPDPVLGSVASMSSATPDSSASVERGS 382
C C + F + + H +H +P N + S + +
Sbjct: 418 CDDCGKAFRNKSYLSVHQKTHTEEKPYQCN--------------------ECGKSFKNTT 457
Query: 383 TPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHT 442
+ + G+K R C C K + S + L +H++T +KP +
Sbjct: 458 IFNVHQRIHTGEKPFR------------CNECGKA-YRSNSSLIVHIRTHTGEKP---YE 501
Query: 443 CQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVS 502
C C + + N EH +++H + CN C + F + + L H R+
Sbjct: 502 CNECGKAFNRIANFTEH-QRIHTGE----------KPYKCNECGKAFINYSCLTVHHRM- 549
Query: 503 HCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEV 562
G + C +C F+ SSL H Q+ H E P
Sbjct: 550 --------HTGEKPYKCTECGKAFMRSSSLIIH-QRIHTE------EKP----------- 583
Query: 563 YSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSA 622
Y C C G ++ H+ + +
Sbjct: 584 YLCNEC------GESFRIKSHLTVHQR--------------------------------- 604
Query: 623 SANSISNGE--YPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQH 680
I GE Y C C+ F+ + + H K+H ++ C C + F ++ L+ H
Sbjct: 605 ----IHTGEKPYKCTDCERAFTKMVNLKEHQKIHTG--VKPYKCYDCGKSFRTKSYLIVH 658
Query: 681 LTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLA 740
H T Y C C+K F++ L H Y C C +VF S H
Sbjct: 659 QRTH--TGEKPYKCNECEKAFTNTSQLTVHQRRHTGEKPYKCNECGKVFTSNSGFNTHQR 716
Query: 741 VKHSNEKKMYRCTACNWDFRKEADLQVHV-KHSHLGNPAKAHKCIFCGETFSTEVELQCH 799
H+ EK ++C C F + VHV +H + + K +KC CG+ F L H
Sbjct: 717 T-HTGEKP-FKCNDCGKAFSQ----MVHVTEHQKIHSGEKPYKCDVCGKAFRRGSYLTVH 770
Query: 800 ITTHS--KKYNCKFCSKAFHAIILLEKHLR 827
TH+ K Y CK C K + L H R
Sbjct: 771 WRTHTGEKPYTCKECGKGCITLSQLTLHQR 800
Score = 159 bits (402), Expect = 2e-38
Identities = 159/639 (24%), Positives = 243/639 (38%), Gaps = 111/639 (17%)
Query: 409 YSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHA 468
Y C C K F + + L +H + +KP Q C +C S LN+H R
Sbjct: 332 YKCNECGKA-FIASSSLMVHQRIHTKEKPYQ---CNVCGKSFSQCARLNQHQR------- 380
Query: 469 YPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLT 528
+Q G + C+ C + F+D + L H +G + C+ C F
Sbjct: 381 ---IQTGE-KPYKCSECGKAFSDKSKLARH---------QETHNGEKPYKCDDCGKAFRN 427
Query: 529 ESSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENH 588
+S L+ H Q T + + Y C C S +I + + I
Sbjct: 428 KSYLSVH------------------QKTHTEEKPYQCNECGKSFKNTTIFNVHQRIHTGE 469
Query: 589 KNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQ 648
K P ++ KA +S S V + + ++ Y CN+C F+ +F
Sbjct: 470 K--PFRCNECGKAYRSNSSLIVHIRTHTGEK-----------PYECNECGKAFNRIANFT 516
Query: 649 THLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQ 708
H ++H + C +C + F + L H +H T Y C C K F L
Sbjct: 517 EHQRIHTGE--KPYKCNECGKAFINYSCLTVHHRMH--TGEKPYKCTECGKAFMRSSSLI 572
Query: 709 KHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVH 768
H Y C C E F K + VH + H+ EK Y+CT C F K +L+ H
Sbjct: 573 IHQRIHTEEKPYLCNECGESFRIKSHLTVHQRI-HTGEKP-YKCTDCERAFTKMVNLKEH 630
Query: 769 VKHSHLGNPAKAHKCIFCGETFSTEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHL 826
K H G K +KC CG++F T+ L H TH+ K Y C C KAF L H
Sbjct: 631 QK-IHTG--VKPYKCYDCGKSFRTKSYLIVHQRTHTGEKPYKCNECEKAFTNTSQLTVHQ 687
Query: 827 REKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMY 886
R G P + G + + N+H+ + E +
Sbjct: 688 RRH-------------TGEKPYKCNEC------GKVFTSNSGFNTHQRTH----TGEKPF 724
Query: 887 GCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLR 946
C+ CG A++ V + H+ I GE +KC+VC + F + L
Sbjct: 725 KCNDCGKAFSQMVHVTEHQ----KIHSGEK------------PYKCDVCGKAFRRGSYLT 768
Query: 947 EHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEH 1006
H +TH G K Y C CG+ +L LT H+ H+ C C ++ +F H
Sbjct: 769 VHWRTHTG-EKPYTCKECGKGCITLSQLTLHQRIHTGERPY-KCEECGKAFRTNSDFTVH 826
Query: 1007 CQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQK 1045
+MH + ++C C + S+ L +H H ++
Sbjct: 827 LRMHTGEK----PYKCNECGKAFRSSSSLTVHQRIHQRE 861
Score = 150 bits (380), Expect = 6e-36
Identities = 137/626 (21%), Positives = 222/626 (35%), Gaps = 121/626 (19%)
Query: 64 ESIYTCDHCQQDFESLADLTDHRAHRCPGDGDDDPQLSWVASSPSSKDVASPTQMIGDGC 123
E Y C+ C + F A L H+ + + + + D
Sbjct: 357 EKPYQCNVCGKSFSQCARLNQHQR---------------IQTGEKPYKCSECGKAFSDKS 401
Query: 124 DLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDR 183
L +E PY C C K+F SYL H++ H+++ P++C C + FK+ +
Sbjct: 402 KLARHQETHNGEKPYKCDDCGKAFRNKSYLSVHQKTHTEEKPYQCNECGKSFKNTTIFNV 461
Query: 184 HIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQA 243
H ++HTG+K + C+EC A+ + L +H++TH+ KP++C C + F+ ++ H +
Sbjct: 462 HQRIHTGEKPFRCNECGKAYRSNSSLIVHIRTHTGEKPYECNECGKAFNRIANFTEHQRI 521
Query: 244 HKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEV 303
H K + C+ C F L H H + + +C C +
Sbjct: 522 HTGEK-------------PYKCNECGKAFINYSCLTVH----HRMHTGEKPYKCTECGKA 564
Query: 304 FVDENTLLAHIHQAHANQK-HKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLG 362
F+ ++L+ H + H +K + C C E F + HL H++ +
Sbjct: 565 FMRSSSLIIH-QRIHTEEKPYLCNECGESFR----IKSHLTVHQRIHTGE---------- 609
Query: 363 SVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSL 422
P ER T LK +K+ + Y C C K F +
Sbjct: 610 --------KPYKCTDCERAFTKMVNLKE---HQKIHTGVK-----PYKCYDCGK-SFRTK 652
Query: 423 AVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHC 482
+ L +H +T +KP + C C + L H R+ H + C
Sbjct: 653 SYLIVHQRTHTGEKP---YKCNECEKAFTNTSQLTVHQRR-HTGE----------KPYKC 698
Query: 483 NYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCS 542
N C ++F + H R G F CN C F +TEH Q+ H
Sbjct: 699 NECGKVFTSNSGFNTHQRT---------HTGEKPFKCNDCGKAFSQMVHVTEH-QKIHSG 748
Query: 543 VGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAE 602
E P Y C C + GS L + K K
Sbjct: 749 ------EKP-----------YKCDVCGKAFRRGSYLTVHWRTHTGEKPYTCKECGKGCIT 791
Query: 603 QSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQ 662
S ++ + + +R Y C +C F F HL++H +
Sbjct: 792 LSQLTLHQRIHTGER-------------PYKCEECGKAFRTNSDFTVHLRMHTG--EKPY 836
Query: 663 ACPQCKEDFDSQESLLQHLTVHYMTT 688
C +C + F S SL H +H T
Sbjct: 837 KCNECGKAFRSSSSLTVHQRIHQRET 862
Score = 138 bits (348), Expect = 3e-32
Identities = 154/689 (22%), Positives = 241/689 (34%), Gaps = 98/689 (14%)
Query: 606 VSSDVEVSSPKRQRLSASANSISNGE---YPCNQCDLKFSNFESFQTHLKLHLELLLRKQ 662
+ +++ S RQ + SN + Y C+ C+ F H + H + +
Sbjct: 247 ICKEMKGSKAIRQTSELTLGKKSNNKEKPYKCSTCEKAFHYRSLLIQHQRTHTKE--KPY 304
Query: 663 ACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHC 722
C +C + F L QH +H T Y C C K F + L H Y C
Sbjct: 305 ECNECGKTFSQPSYLSQHKKIH--TGEKPYKCNECGKAFIASSSLMVHQRIHTKEKPYQC 362
Query: 723 TLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHK 782
+C + F + H ++ +K Y+C+ C F ++ L +H N K +K
Sbjct: 363 NVCGKSFSQCARLNQHQRIQTG--EKPYKCSECGKAFSDKSKL---ARHQETHNGEKPYK 417
Query: 783 CIFCGETFSTEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENG 840
C CG+ F + L H TH+ K Y C C K+F + H R
Sbjct: 418 CDDCGKAFRNKSYLSVHQKTHTEEKPYQCNECGKSFKNTTIFNVHQR------------- 464
Query: 841 TANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVL 900
G P + A NS E Y C+ CG A+
Sbjct: 465 IHTGEKPFRCNECGKA----------YRSNSSLIVHIRTHTGEKPYECNECGKAFNRIAN 514
Query: 901 LQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYM 960
H+ I GE +KCN C + F + + L H + H G K Y
Sbjct: 515 FTEHQ----RIHTGEK------------PYKCNECGKAFINYSCLTVHHRMHTG-EKPYK 557
Query: 961 CPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGF 1020
C CG+ F +L H+ H++ C C + + H +H + +
Sbjct: 558 CTECGKAFMRSSSLIIHQRIHTEE-KPYLCNECGESFRIK----SHLTVHQRIHTGEKPY 612
Query: 1021 RCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLV 1080
+C C + T + LK H H K YKC C K FR+K L+
Sbjct: 613 KCTDCERAFTKMVNLKEHQKIHTG----------------VKPYKCYDCGKSFRTKSYLI 656
Query: 1081 ---KLDVNGLPYGLCAGCMARSAN-GQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLE 1136
+ PY C C N Q+ ++P +C EC F S
Sbjct: 657 VHQRTHTGEKPY-KCNECEKAFTNTSQLTVHQRRHTGEKP---YKCNECGKVFTSNSGFN 712
Query: 1137 SHMQVDHRDLTPETSGPRKG-------TQTSPV-PRKKTYQCIKCQMTFENEREIQIHVA 1188
+H + + + + K T+ + +K Y+C C F + +H
Sbjct: 713 THQRTHTGEKPFKCNDCGKAFSQMVHVTEHQKIHSGEKPYKCDVCGKAFRRGSYLTVHWR 772
Query: 1189 NHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHI 1248
H E+ + CK C + + ++L H H+ E +KC C F + H+
Sbjct: 773 THTGEK--PYTCKECGKGCITLSQLTLHQRIHTGE---RPYKCEECGKAFRTNSDFTVHL 827
Query: 1249 FAVHGQEDKIYDCSQCPQKFFFQTELQNH 1277
G +K Y C++C + F + L H
Sbjct: 828 RMHTG--EKPYKCNECGKAFRSSSSLTVH 854
Score = 138 bits (347), Expect = 4e-32
Identities = 149/629 (23%), Positives = 231/629 (36%), Gaps = 101/629 (16%)
Query: 645 ESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSV 704
E+F +L L + L K C + K +++ L Y C +C+K F
Sbjct: 229 ENFTENLNLITDTHLGKIICKEMKGSKAIRQTSELTLGKKSNNKEKPYKCSTCEKAFHYR 288
Query: 705 DDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEAD 764
L +H Y C C + F + H + H+ EK Y+C C F +
Sbjct: 289 SLLIQHQRTHTKEKPYECNECGKTFSQPSYLSQHKKI-HTGEKP-YKCNECGKAFIASSS 346
Query: 765 LQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCH--ITTHSKKYNCKFCSKAFHAIILL 822
L VH + + K ++C CG++FS L H I T K Y C C KAF L
Sbjct: 347 LMVHQR---IHTKEKPYQCNVCGKSFSQCARLNQHQRIQTGEKPYKCSECGKAFSDKSKL 403
Query: 823 EKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDAS 882
+H T NG +K D G +N + H+ + +
Sbjct: 404 ARHQE---------THNG----------EKPYKCDDCGKAFRNKSYLSVHQKTHTE---- 440
Query: 883 EPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSE 942
E Y C+ CG ++ + H+ I GE +CN C + + S
Sbjct: 441 EKPYQCNECGKSFKNTTIFNVHQ----RIHTGEKP------------FRCNECGKAYRSN 484
Query: 943 NGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEE 1002
+ L H++TH G K Y C CG+ F + TEH+ H+ C C +
Sbjct: 485 SSLIVHIRTHTGE-KPYECNECGKAFNRIANFTEHQRIHTGEKPY-KCNECGKAFINYSC 542
Query: 1003 FIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQK 1062
H +MH + ++C C + + L IH H + +K
Sbjct: 543 LTVHHRMHTGEKP----YKCTECGKAFMRSSSLIIHQRIHTE----------------EK 582
Query: 1063 LYKCALCLKEFRSKQDLV---KLDVNGLPYGLCAGCMARSANGQVGGLAPPEPADRPCAG 1119
Y C C + FR K L ++ PY C C A ++ L +
Sbjct: 583 PYLCNECGESFRIKSHLTVHQRIHTGEKPYK-CTDC--ERAFTKMVNLKEHQKIHTGVKP 639
Query: 1120 LRCPECSVKFESAEDLESHMQVDHRDLTPETSGPRKGTQTSPVPRKKTYQCIKCQMTFEN 1179
+C +C F + +S++ V R T E K Y+C +C+ F N
Sbjct: 640 YKCYDCGKSFRT----KSYLIVHQRTHTGE----------------KPYKCNECEKAFTN 679
Query: 1180 EREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFV 1239
++ +H H E+ ++C C ++F S + H H+ E FKC C F
Sbjct: 680 TSQLTVHQRRHTGEK--PYKCNECGKVFTSNSGFNTHQRTHTGE---KPFKCNDCGKAFS 734
Query: 1240 QANKLQQHIFAVHGQEDKIYDCSQCPQKF 1268
Q + +H +H E K Y C C + F
Sbjct: 735 QMVHVTEH-QKIHSGE-KPYKCDVCGKAF 761
Score = 132 bits (333), Expect = 2e-30
Identities = 157/677 (23%), Positives = 238/677 (35%), Gaps = 107/677 (15%)
Query: 563 YSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSA 622
Y C C + + S+L +H + + K P ++ K P +S K+
Sbjct: 276 YKCSTCEKAFHYRSLL--IQHQRTHTKEKPYECNECGKTFSQPSY----LSQHKK----- 324
Query: 623 SANSISNGE--YPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQH 680
I GE Y CN+C F S H ++H + + C C + F L QH
Sbjct: 325 ----IHTGEKPYKCNECGKAFIASSSLMVHQRIHTKE--KPYQCNVCGKSFSQCARLNQH 378
Query: 681 LTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLA 740
+ T Y C C K FS L +H + Y C C + F +K + VH
Sbjct: 379 QRIQ--TGEKPYKCSECGKAFSDKSKLARHQETHNGEKPYKCDDCGKAFRNKSYLSVHQ- 435
Query: 741 VKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHI 800
K E+K Y+C C F+ VH + H G K +C CG+ + + L HI
Sbjct: 436 -KTHTEEKPYQCNECGKSFKNTTIFNVH-QRIHTGE--KPFRCNECGKAYRSNSSLIVHI 491
Query: 801 TTHS--KKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADL 858
TH+ K Y C C KAF+ I +H R G P +
Sbjct: 492 RTHTGEKPYECNECGKAFNRIANFTEHQR-------------IHTGEKPYKCNEC----- 533
Query: 859 QGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDG 918
G N H + E Y C CG A+ L H+ +P
Sbjct: 534 -GKAFINYSCLTVHHR----MHTGEKPYKCTECGKAFMRSSSLIIHQRIHTEEKP----- 583
Query: 919 SRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHK 978
+ CN C +F ++ L H + H G K Y C C F ++ L EH+
Sbjct: 584 -----------YLCNECGESFRIKSHLTVHQRIHTGE-KPYKCTDCERAFTKMVNLKEHQ 631
Query: 979 VTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIH 1038
H+ + C C +++ I H + H + ++C C + T+T +L +H
Sbjct: 632 KIHT-GVKPYKCYDCGKSFRTKSYLIVHQRTHTGEKP----YKCNECEKAFTNTSQLTVH 686
Query: 1039 GTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDL---VKLDVNGLPYGLCAGC 1095
H +K YKC C K F S + P+ C C
Sbjct: 687 QRRHTG----------------EKPYKCNECGKVFTSNSGFNTHQRTHTGEKPFK-CNDC 729
Query: 1096 MARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPET----- 1150
A Q+ + + +C C F L H + H P T
Sbjct: 730 --GKAFSQMVHVTEHQKIHSGEKPYKCDVCGKAFRRGSYLTVHWRT-HTGEKPYTCKECG 786
Query: 1151 SGPRKGTQTSPVPR----KKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQM 1206
G +Q + R ++ Y+C +C F + +H+ H E+ ++C C +
Sbjct: 787 KGCITLSQLTLHQRIHTGERPYKCEECGKAFRTNSDFTVHLRMHTGEK--PYKCNECGKA 844
Query: 1207 FDSPAKLLCHLIEHSFE 1223
F S + L H H E
Sbjct: 845 FRSSSSLTVHQRIHQRE 861
Score = 94.7 bits (234), Expect = 5e-19
Identities = 55/214 (25%), Positives = 93/214 (43%), Gaps = 43/214 (20%)
Query: 64 ESIYTCDHCQQDFESLADLTDHRAHRCPGDGDDDPQLSWVASSPSSKDVASPTQMIGDGC 123
E Y C+ C++ F + + LT H+ + V +S S + T
Sbjct: 665 EKPYKCNECEKAFTNTSQLTVHQRRHTGEKPYKCNECGKVFTSNSGFNTHQRTHT----- 719
Query: 124 DLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFK------- 176
GE+ P+ C C K+F ++ ++ H++IHS + P+KC C + F+
Sbjct: 720 ----GEK------PFKCNDCGKAFSQMVHVTEHQKIHSGEKPYKCDVCGKAFRRGSYLTV 769
Query: 177 HKRSRDR---------------------HIKLHTGDKKYHCHECEAAFSRSDHLKIHLKT 215
H R+ H ++HTG++ Y C EC AF + +HL+
Sbjct: 770 HWRTHTGEKPYTCKECGKGCITLSQLTLHQRIHTGERPYKCEECGKAFRTNSDFTVHLRM 829
Query: 216 HSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKE 249
H+ KP+KC C + F S+SSL H + H++ +
Sbjct: 830 HTGEKPYKCNECGKAFRSSSSLTVHQRIHQRETQ 863
Score = 53.1 bits (126), Expect = 2e-06
Identities = 33/121 (27%), Positives = 58/121 (47%), Gaps = 7/121 (5%)
Query: 1164 RKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFE 1223
++K Y+C +C TF + H H E+ ++C C + F + + L+ H H+ E
Sbjct: 300 KEKPYECNECGKTFSQPSYLSQHKKIHTGEKP--YKCNECGKAFIASSSLMVHQRIHTKE 357
Query: 1224 GMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNHTMSQHA 1283
++C VC F Q +L QH G+ K Y CS+C + F +++L H + +
Sbjct: 358 K---PYQCNVCGKSFSQCARLNQHQRIQTGE--KPYKCSECGKAFSDKSKLARHQETHNG 412
Query: 1284 Q 1284
+
Sbjct: 413 E 413
>gi|156547246 zinc finger protein 160 [Homo sapiens]
Length = 818
Score = 186 bits (473), Expect = 9e-47
Identities = 174/677 (25%), Positives = 249/677 (36%), Gaps = 125/677 (18%)
Query: 135 GLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKY 194
G PY C C K+F + S L H +IHS + P+KC+ C + F + + H +HTG+K Y
Sbjct: 254 GKPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIHTGEKPY 313
Query: 195 HCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKS 254
CHEC F + +L H + H+ KP+KC C + F S+L +H H K
Sbjct: 314 KCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFRGHSNLTTHQLIHTGEK------ 367
Query: 255 EKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHI 314
F C+ C F+Q L H + + +C C + F ++L H
Sbjct: 368 -------PFKCNECGKLFTQNSHLISHWRIH----TGEKPYKCNECGKAFSVRSSLAIH- 415
Query: 315 HQAHANQK-HKCPMCPE--QFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSAT 371
H +K +KC C + +++S G + + + +P N G SM S
Sbjct: 416 QTIHTGEKPYKCNECGKVFRYNSYLGRHRRVHTGEKPYKCNE-------CGKAFSMHSNL 468
Query: 372 PDSSASVERGSTP---DSTLKPLRGQKKMRDDGQGWT-KVVYSCPYCSKRDFNSLAVLEI 427
+ G+ P + K ++ + + T + Y C C K F+ + L
Sbjct: 469 ATHQV-IHTGTKPFKCNECSKVFTQNSQLANHRRIHTGEKPYKCNECGKA-FSVRSSLTT 526
Query: 428 HLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPE 487
H +KP + C C S +L H R +H + CN C +
Sbjct: 527 HQAIHSGEKP---YKCIECGKSFTQKSHLRSH-RGIHSGE----------KPYKCNECGK 572
Query: 488 MFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAK 547
+FA + L H RV G + CN C F SSLT H Q H
Sbjct: 573 VFAQTSQLARHWRV---------HTGEKPYKCNDCGRAFSDRSSLTFH-QAIHTG----- 617
Query: 548 LESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVS 607
E P Y C C K+ +H N LA ++ + P
Sbjct: 618 -EKP-----------YKCHECG---------KVFRH------NSYLATHRRIHTGEKP-- 648
Query: 608 SDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQC 667
Y CN+C FS + TH +H + C QC
Sbjct: 649 ------------------------YKCNECGKAFSMHSNLTTHKVIHTG--EKPYKCNQC 682
Query: 668 KEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQE 727
+ F L H H T Y C C K FS L H Y C C +
Sbjct: 683 GKVFTQNSHLANHQRTH--TGEKPYRCNECGKAFSVRSSLTTHQAIHTGKKPYKCNECGK 740
Query: 728 VFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCG 787
VF + H + H+ EK YRCT C FR + L H+ H G K +KC CG
Sbjct: 741 VFTQNAHLANHRRI-HTGEKP-YRCTECGKAFRVRSSLTTHMA-IHTGE--KRYKCNECG 795
Query: 788 ETFSTEVELQCHITTHS 804
+ F L H H+
Sbjct: 796 KVFRQSSNLASHHRMHT 812
Score = 144 bits (363), Expect = 5e-34
Identities = 154/664 (23%), Positives = 235/664 (35%), Gaps = 131/664 (19%)
Query: 632 YPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTH 691
Y CN+C F+ + +H ++H + C +C + F + +L H +H T
Sbjct: 257 YKCNECGKAFTQNSNLTSHRRIHSGE--KPYKCSECGKTFTVRSNLTIHQVIH--TGEKP 312
Query: 692 YVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYR 751
Y C C K F L H Y C C + F ++ H + H+ EK ++
Sbjct: 313 YKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFRGHSNLTTHQLI-HTGEKP-FK 370
Query: 752 CTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHITTHS--KKYNC 809
C C F + + L + H + K +KC CG+ FS L H T H+ K Y C
Sbjct: 371 CNECGKLFTQNSHL---ISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTGEKPYKC 427
Query: 810 KFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAP 869
C K F L +H R
Sbjct: 428 NECGKVFRYNSYLGRHRR------------------------------------------ 445
Query: 870 NSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGS 929
V E Y C+ CG A++M L H++ +P
Sbjct: 446 ---------VHTGEKPYKCNECGKAFSMHSNLATHQVIHTGTKP---------------- 480
Query: 930 HKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGT 989
KCN CS+ F + L H + H G K Y C CG+ F +LT H+ HS
Sbjct: 481 FKCNECSKVFTQNSQLANHRRIHTG-EKPYKCNECGKAFSVRSSLTTHQAIHSGEKPYKC 539
Query: 990 CRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQK---- 1045
K Q H + H + + ++C C + T +L H H +
Sbjct: 540 IECGKSFTQK-----SHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARHWRVHTGEKPYK 594
Query: 1046 -----LAGSSAASSPNGQGL---QKLYKCALCLKEFRSKQDLV---KLDVNGLPYGLCAG 1094
A S +S Q + +K YKC C K FR L ++ PY C
Sbjct: 595 CNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPY-KCNE 653
Query: 1095 C-MARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGP 1153
C A S + + ++P +C +C F L +H +
Sbjct: 654 CGKAFSMHSNLTTHKVIHTGEKP---YKCNQCGKVFTQNSHLANHQR------------- 697
Query: 1154 RKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKL 1213
T T +K Y+C +C F + H A H ++ ++C C ++F A L
Sbjct: 698 ---THTG----EKPYRCNECGKAFSVRSSLTTHQAIHTGKK--PYKCNECGKVFTQNAHL 748
Query: 1214 LCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTE 1273
H H+ E ++C C F + L H+ A+H E K Y C++C + F +
Sbjct: 749 ANHRRIHTGE---KPYRCTECGKAFRVRSSLTTHM-AIHTGE-KRYKCNECGKVFRQSSN 803
Query: 1274 LQNH 1277
L +H
Sbjct: 804 LASH 807
Score = 140 bits (354), Expect = 6e-33
Identities = 154/627 (24%), Positives = 231/627 (36%), Gaps = 106/627 (16%)
Query: 480 FHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQA 539
+ CN C + F ++L H R+ G + C++C F S+LT H Q
Sbjct: 257 YKCNECGKAFTQNSNLTSHRRIH---------SGEKPYKCSECGKTFTVRSNLTIH-QVI 306
Query: 540 HCSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKS 599
H E P Y C C S L + I K K+
Sbjct: 307 HTG------EKP-----------YKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKA 349
Query: 600 KAEQSPVSSDVEVSSPKR--------QRLSASANSISN-----GE--YPCNQCDLKFSNF 644
S +++ + + ++ + + +++ IS+ GE Y CN+C FS
Sbjct: 350 FRGHSNLTTHQLIHTGEKPFKCNECGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVR 409
Query: 645 ESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSV 704
S H +H + C +C + F L +H VH T Y C C K FS
Sbjct: 410 SSLAIHQTIHTGE--KPYKCNECGKVFRYNSYLGRHRRVH--TGEKPYKCNECGKAFSMH 465
Query: 705 DDLQKHLLDMHTFVL-YHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEA 763
+L H + +HT + C C +VF + H + H+ EK Y+C C F +
Sbjct: 466 SNLATHQV-IHTGTKPFKCNECSKVFTQNSQLANHRRI-HTGEKP-YKCNECGKAFSVRS 522
Query: 764 DLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHITTHS--KKYNCKFCSKAFHAIIL 821
L H + H G K +KCI CG++F+ + L+ H HS K Y C C K F
Sbjct: 523 SLTTH-QAIHSGE--KPYKCIECGKSFTQKSHLRSHRGIHSGEKPYKCNECGKVFAQTSQ 579
Query: 822 LEKHLR----EK-----HCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAPNSH 872
L +H R EK C + + +K G + ++ NS+
Sbjct: 580 LARHWRVHTGEKPYKCNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRH----NSY 635
Query: 873 EASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKC 932
A+ + E Y C+ CG A++M L H++ I GE +KC
Sbjct: 636 LATHRRIHTGEKPYKCNECGKAFSMHSNLTTHKV----IHTGEK------------PYKC 679
Query: 933 NVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRI 992
N C + F + L H +TH G K Y C CG+ F +LT H+ H+ C
Sbjct: 680 NQCGKVFTQNSHLANHQRTHTG-EKPYRCNECGKAFSVRSSLTTHQAIHT-GKKPYKCNE 737
Query: 993 CKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAA 1052
C H ++H + +RC C + L H H
Sbjct: 738 CGKVFTQNAHLANHRRIHTGEK----PYRCTECGKAFRVRSSLTTHMAIHTG-------- 785
Query: 1053 SSPNGQGLQKLYKCALCLKEFRSKQDL 1079
+K YKC C K FR +L
Sbjct: 786 --------EKRYKCNECGKVFRQSSNL 804
Score = 125 bits (315), Expect = 2e-28
Identities = 84/305 (27%), Positives = 127/305 (41%), Gaps = 50/305 (16%)
Query: 64 ESIYTCDHCQQDFESLADLTDHRA-------HRCPGDGDDDPQLSWVASSPSSKDVASPT 116
E Y C+ C + F + LT H+A ++C G Q S + S
Sbjct: 506 EKPYKCNECGKAFSVRSSLTTHQAIHSGEKPYKCIECGKSFTQKSHLRSHRG-------- 557
Query: 117 QMIGDGCDLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFK 176
+ GE+ PY C C K F + S L RH ++H+ + P+KC C R F
Sbjct: 558 --------IHSGEK------PYKCNECGKVFAQTSQLARHWRVHTGEKPYKCNDCGRAFS 603
Query: 177 HKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSS 236
+ S H +HTG+K Y CHEC F + +L H + H+ KP+KC C + FS S+
Sbjct: 604 DRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFSMHSN 663
Query: 237 LQSHMQAHKKNK--------------EHLAKSEK-EAKKDDFMCDYCEDTFSQTEELEKH 281
L +H H K HLA ++ + + C+ C FS L H
Sbjct: 664 LTTHKVIHTGEKPYKCNQCGKVFTQNSHLANHQRTHTGEKPYRCNECGKAFSVRSSLTTH 723
Query: 282 VLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQAHANQK-HKCPMCPEQFSSVEGVYC 340
+ K +C C +VF +N LA+ + H +K ++C C + F +
Sbjct: 724 QAIH----TGKKPYKCNECGKVFT-QNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTT 778
Query: 341 HLDSH 345
H+ H
Sbjct: 779 HMAIH 783
Score = 105 bits (262), Expect = 3e-22
Identities = 134/548 (24%), Positives = 187/548 (34%), Gaps = 128/548 (23%)
Query: 779 KAHKCIFCGETFSTEVELQCHITTHS--KKYNCKFCSKAF--------HAIILL-EKHLR 827
K +KC CG+ F+ L H HS K Y C C K F H +I EK +
Sbjct: 255 KPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIHTGEKPYK 314
Query: 828 EKHC--VFD----AATENGTANGVPPMATKKAEPADLQG-------MLLKNPEAP----- 869
C VF AT G P + A +G L+ E P
Sbjct: 315 CHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKA-FRGHSNLTTHQLIHTGEKPFKCNE 373
Query: 870 -------NSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKK 922
NSH S + E Y C+ CG A+++ L H+ I GE
Sbjct: 374 CGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQ----TIHTGEK------ 423
Query: 923 AEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHS 982
+KCN C + F + L H + H G K Y C CG+ F L H+V H
Sbjct: 424 ------PYKCNECGKVFRYNSYLGRHRRVHTG-EKPYKCNECGKAFSMHSNLATHQVIH- 475
Query: 983 KSLDTGT----CRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIH 1038
TGT C C + H ++H + ++C C + + L H
Sbjct: 476 ----TGTKPFKCNECSKVFTQNSQLANHRRIHTGEK----PYKCNECGKAFSVRSSLTTH 527
Query: 1039 GTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLVKLDVNGLPYGLCAGCMAR 1098
H +K YKC C K F K L R
Sbjct: 528 QAIHSG----------------EKPYKCIECGKSFTQKSHL------------------R 553
Query: 1099 SANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGP--RKG 1156
S G G P +C EC F L H +V H P R
Sbjct: 554 SHRGIHSGEKP----------YKCNECGKVFAQTSQLARHWRV-HTGEKPYKCNDCGRAF 602
Query: 1157 TQTSPV-------PRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDS 1209
+ S + +K Y+C +C F + + H H E+ ++C C + F
Sbjct: 603 SDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEK--PYKCNECGKAFSM 660
Query: 1210 PAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFF 1269
+ L H + H+ E +KC C VF Q + L H G +K Y C++C + F
Sbjct: 661 HSNLTTHKVIHTGE---KPYKCNQCGKVFTQNSHLANHQRTHTG--EKPYRCNECGKAFS 715
Query: 1270 FQTELQNH 1277
++ L H
Sbjct: 716 VRSSLTTH 723
Score = 96.7 bits (239), Expect = 1e-19
Identities = 57/194 (29%), Positives = 85/194 (43%), Gaps = 29/194 (14%)
Query: 64 ESIYTCDHCQQDFESLADLTDHRA-------HRCPGDGDDDPQLSWVASSPSSKDVASPT 116
E Y C+ C + F ++LT H+ ++C G Q S +A+ +
Sbjct: 646 EKPYKCNECGKAFSMHSNLTTHKVIHTGEKPYKCNQCGKVFTQNSHLANHQRTHT----- 700
Query: 117 QMIGDGCDLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFK 176
GE+ PY C C K+F S L H+ IH+ K P+KC C ++F
Sbjct: 701 -----------GEK------PYRCNECGKAFSVRSSLTTHQAIHTGKKPYKCNECGKVFT 743
Query: 177 HKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSS 236
H ++HTG+K Y C EC AF L H+ H+ K +KC C + F +S+
Sbjct: 744 QNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTTHMAIHTGEKRYKCNECGKVFRQSSN 803
Query: 237 LQSHMQAHKKNKEH 250
L SH + H K +
Sbjct: 804 LASHHRMHTGEKPY 817
Score = 89.7 bits (221), Expect = 2e-17
Identities = 101/403 (25%), Positives = 149/403 (36%), Gaps = 44/403 (10%)
Query: 901 LQNHRLRD-HNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHY 959
+Q HR + H + R+KA +KCN C + F + L H + H G K Y
Sbjct: 227 VQTHRSKKYHELNHFSLLTQRRKANSCGKPYKCNECGKAFTQNSNLTSHRRIHSG-EKPY 285
Query: 960 MCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTG 1019
C CG+ F LT H+V H+ C C + H ++H +
Sbjct: 286 KCSECGKTFTVRSNLTIHQVIHTGE-KPYKCHECGKVFRHNSYLATHRRIHTGEK----P 340
Query: 1020 FRCVVCMQTVTSTLELKIHGTFHMQK------------LAGSSAASSPNGQGLQKLYKCA 1067
++C C + L H H + S S +K YKC
Sbjct: 341 YKCNECGKAFRGHSNLTTHQLIHTGEKPFKCNECGKLFTQNSHLISHWRIHTGEKPYKCN 400
Query: 1068 LCLKEFRSKQDLV---KLDVNGLPYGLCAGC-MARSANGQVGGLAPPEPADRPCAGLRCP 1123
C K F + L + PY C C N +G ++P +C
Sbjct: 401 ECGKAFSVRSSLAIHQTIHTGEKPY-KCNECGKVFRYNSYLGRHRRVHTGEKP---YKCN 456
Query: 1124 ECSVKFESAEDLESHMQVDHRDLTPETSG--PRKGTQTSPVPR-------KKTYQCIKCQ 1174
EC F +L +H QV H P + TQ S + +K Y+C +C
Sbjct: 457 ECGKAFSMHSNLATH-QVIHTGTKPFKCNECSKVFTQNSQLANHRRIHTGEKPYKCNECG 515
Query: 1175 MTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVC 1234
F + H A H E+ ++C C + F + L H HS E +KC C
Sbjct: 516 KAFSVRSSLTTHQAIHSGEK--PYKCIECGKSFTQKSHLRSHRGIHSGE---KPYKCNEC 570
Query: 1235 FTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNH 1277
VF Q ++L +H + VH E K Y C+ C + F ++ L H
Sbjct: 571 GKVFAQTSQLARH-WRVHTGE-KPYKCNDCGRAFSDRSSLTFH 611
Score = 43.5 bits (101), Expect = 0.001
Identities = 31/114 (27%), Positives = 49/114 (42%), Gaps = 7/114 (6%)
Query: 1166 KTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGM 1225
K Y+C +C F + H H E+ ++C C + F + L H + H+ E
Sbjct: 255 KPYKCNECGKAFTQNSNLTSHRRIHSGEKP--YKCSECGKTFTVRSNLTIHQVIHTGEK- 311
Query: 1226 GGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNHTM 1279
+KC C VF + L H +H E K Y C++C + F + L H +
Sbjct: 312 --PYKCHECGKVFRHNSYLATHR-RIHTGE-KPYKCNECGKAFRGHSNLTTHQL 361
>gi|38788302 zinc finger protein 160 [Homo sapiens]
Length = 818
Score = 186 bits (473), Expect = 9e-47
Identities = 174/677 (25%), Positives = 249/677 (36%), Gaps = 125/677 (18%)
Query: 135 GLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKY 194
G PY C C K+F + S L H +IHS + P+KC+ C + F + + H +HTG+K Y
Sbjct: 254 GKPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIHTGEKPY 313
Query: 195 HCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKS 254
CHEC F + +L H + H+ KP+KC C + F S+L +H H K
Sbjct: 314 KCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFRGHSNLTTHQLIHTGEK------ 367
Query: 255 EKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHI 314
F C+ C F+Q L H + + +C C + F ++L H
Sbjct: 368 -------PFKCNECGKLFTQNSHLISHWRIH----TGEKPYKCNECGKAFSVRSSLAIH- 415
Query: 315 HQAHANQK-HKCPMCPE--QFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSAT 371
H +K +KC C + +++S G + + + +P N G SM S
Sbjct: 416 QTIHTGEKPYKCNECGKVFRYNSYLGRHRRVHTGEKPYKCNE-------CGKAFSMHSNL 468
Query: 372 PDSSASVERGSTP---DSTLKPLRGQKKMRDDGQGWT-KVVYSCPYCSKRDFNSLAVLEI 427
+ G+ P + K ++ + + T + Y C C K F+ + L
Sbjct: 469 ATHQV-IHTGTKPFKCNECSKVFTQNSQLANHRRIHTGEKPYKCNECGKA-FSVRSSLTT 526
Query: 428 HLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPE 487
H +KP + C C S +L H R +H + CN C +
Sbjct: 527 HQAIHSGEKP---YKCIECGKSFTQKSHLRSH-RGIHSGE----------KPYKCNECGK 572
Query: 488 MFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAK 547
+FA + L H RV G + CN C F SSLT H Q H
Sbjct: 573 VFAQTSQLARHWRV---------HTGEKPYKCNDCGRAFSDRSSLTFH-QAIHTG----- 617
Query: 548 LESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVS 607
E P Y C C K+ +H N LA ++ + P
Sbjct: 618 -EKP-----------YKCHECG---------KVFRH------NSYLATHRRIHTGEKP-- 648
Query: 608 SDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQC 667
Y CN+C FS + TH +H + C QC
Sbjct: 649 ------------------------YKCNECGKAFSMHSNLTTHKVIHTG--EKPYKCNQC 682
Query: 668 KEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQE 727
+ F L H H T Y C C K FS L H Y C C +
Sbjct: 683 GKVFTQNSHLANHQRTH--TGEKPYRCNECGKAFSVRSSLTTHQAIHTGKKPYKCNECGK 740
Query: 728 VFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCG 787
VF + H + H+ EK YRCT C FR + L H+ H G K +KC CG
Sbjct: 741 VFTQNAHLANHRRI-HTGEKP-YRCTECGKAFRVRSSLTTHMA-IHTGE--KRYKCNECG 795
Query: 788 ETFSTEVELQCHITTHS 804
+ F L H H+
Sbjct: 796 KVFRQSSNLASHHRMHT 812
Score = 144 bits (363), Expect = 5e-34
Identities = 154/664 (23%), Positives = 235/664 (35%), Gaps = 131/664 (19%)
Query: 632 YPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTH 691
Y CN+C F+ + +H ++H + C +C + F + +L H +H T
Sbjct: 257 YKCNECGKAFTQNSNLTSHRRIHSGE--KPYKCSECGKTFTVRSNLTIHQVIH--TGEKP 312
Query: 692 YVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYR 751
Y C C K F L H Y C C + F ++ H + H+ EK ++
Sbjct: 313 YKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFRGHSNLTTHQLI-HTGEKP-FK 370
Query: 752 CTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHITTHS--KKYNC 809
C C F + + L + H + K +KC CG+ FS L H T H+ K Y C
Sbjct: 371 CNECGKLFTQNSHL---ISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTGEKPYKC 427
Query: 810 KFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAP 869
C K F L +H R
Sbjct: 428 NECGKVFRYNSYLGRHRR------------------------------------------ 445
Query: 870 NSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGS 929
V E Y C+ CG A++M L H++ +P
Sbjct: 446 ---------VHTGEKPYKCNECGKAFSMHSNLATHQVIHTGTKP---------------- 480
Query: 930 HKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGT 989
KCN CS+ F + L H + H G K Y C CG+ F +LT H+ HS
Sbjct: 481 FKCNECSKVFTQNSQLANHRRIHTG-EKPYKCNECGKAFSVRSSLTTHQAIHSGEKPYKC 539
Query: 990 CRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQK---- 1045
K Q H + H + + ++C C + T +L H H +
Sbjct: 540 IECGKSFTQK-----SHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARHWRVHTGEKPYK 594
Query: 1046 -----LAGSSAASSPNGQGL---QKLYKCALCLKEFRSKQDLV---KLDVNGLPYGLCAG 1094
A S +S Q + +K YKC C K FR L ++ PY C
Sbjct: 595 CNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPY-KCNE 653
Query: 1095 C-MARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGP 1153
C A S + + ++P +C +C F L +H +
Sbjct: 654 CGKAFSMHSNLTTHKVIHTGEKP---YKCNQCGKVFTQNSHLANHQR------------- 697
Query: 1154 RKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKL 1213
T T +K Y+C +C F + H A H ++ ++C C ++F A L
Sbjct: 698 ---THTG----EKPYRCNECGKAFSVRSSLTTHQAIHTGKK--PYKCNECGKVFTQNAHL 748
Query: 1214 LCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTE 1273
H H+ E ++C C F + L H+ A+H E K Y C++C + F +
Sbjct: 749 ANHRRIHTGE---KPYRCTECGKAFRVRSSLTTHM-AIHTGE-KRYKCNECGKVFRQSSN 803
Query: 1274 LQNH 1277
L +H
Sbjct: 804 LASH 807
Score = 140 bits (354), Expect = 6e-33
Identities = 154/627 (24%), Positives = 231/627 (36%), Gaps = 106/627 (16%)
Query: 480 FHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQA 539
+ CN C + F ++L H R+ G + C++C F S+LT H Q
Sbjct: 257 YKCNECGKAFTQNSNLTSHRRIH---------SGEKPYKCSECGKTFTVRSNLTIH-QVI 306
Query: 540 HCSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKS 599
H E P Y C C S L + I K K+
Sbjct: 307 HTG------EKP-----------YKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKA 349
Query: 600 KAEQSPVSSDVEVSSPKR--------QRLSASANSISN-----GE--YPCNQCDLKFSNF 644
S +++ + + ++ + + +++ IS+ GE Y CN+C FS
Sbjct: 350 FRGHSNLTTHQLIHTGEKPFKCNECGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVR 409
Query: 645 ESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSV 704
S H +H + C +C + F L +H VH T Y C C K FS
Sbjct: 410 SSLAIHQTIHTGE--KPYKCNECGKVFRYNSYLGRHRRVH--TGEKPYKCNECGKAFSMH 465
Query: 705 DDLQKHLLDMHTFVL-YHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEA 763
+L H + +HT + C C +VF + H + H+ EK Y+C C F +
Sbjct: 466 SNLATHQV-IHTGTKPFKCNECSKVFTQNSQLANHRRI-HTGEKP-YKCNECGKAFSVRS 522
Query: 764 DLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHITTHS--KKYNCKFCSKAFHAIIL 821
L H + H G K +KCI CG++F+ + L+ H HS K Y C C K F
Sbjct: 523 SLTTH-QAIHSGE--KPYKCIECGKSFTQKSHLRSHRGIHSGEKPYKCNECGKVFAQTSQ 579
Query: 822 LEKHLR----EK-----HCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAPNSH 872
L +H R EK C + + +K G + ++ NS+
Sbjct: 580 LARHWRVHTGEKPYKCNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRH----NSY 635
Query: 873 EASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKC 932
A+ + E Y C+ CG A++M L H++ I GE +KC
Sbjct: 636 LATHRRIHTGEKPYKCNECGKAFSMHSNLTTHKV----IHTGEK------------PYKC 679
Query: 933 NVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRI 992
N C + F + L H +TH G K Y C CG+ F +LT H+ H+ C
Sbjct: 680 NQCGKVFTQNSHLANHQRTHTG-EKPYRCNECGKAFSVRSSLTTHQAIHT-GKKPYKCNE 737
Query: 993 CKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAA 1052
C H ++H + +RC C + L H H
Sbjct: 738 CGKVFTQNAHLANHRRIHTGEK----PYRCTECGKAFRVRSSLTTHMAIHTG-------- 785
Query: 1053 SSPNGQGLQKLYKCALCLKEFRSKQDL 1079
+K YKC C K FR +L
Sbjct: 786 --------EKRYKCNECGKVFRQSSNL 804
Score = 125 bits (315), Expect = 2e-28
Identities = 84/305 (27%), Positives = 127/305 (41%), Gaps = 50/305 (16%)
Query: 64 ESIYTCDHCQQDFESLADLTDHRA-------HRCPGDGDDDPQLSWVASSPSSKDVASPT 116
E Y C+ C + F + LT H+A ++C G Q S + S
Sbjct: 506 EKPYKCNECGKAFSVRSSLTTHQAIHSGEKPYKCIECGKSFTQKSHLRSHRG-------- 557
Query: 117 QMIGDGCDLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFK 176
+ GE+ PY C C K F + S L RH ++H+ + P+KC C R F
Sbjct: 558 --------IHSGEK------PYKCNECGKVFAQTSQLARHWRVHTGEKPYKCNDCGRAFS 603
Query: 177 HKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSS 236
+ S H +HTG+K Y CHEC F + +L H + H+ KP+KC C + FS S+
Sbjct: 604 DRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFSMHSN 663
Query: 237 LQSHMQAHKKNK--------------EHLAKSEK-EAKKDDFMCDYCEDTFSQTEELEKH 281
L +H H K HLA ++ + + C+ C FS L H
Sbjct: 664 LTTHKVIHTGEKPYKCNQCGKVFTQNSHLANHQRTHTGEKPYRCNECGKAFSVRSSLTTH 723
Query: 282 VLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQAHANQK-HKCPMCPEQFSSVEGVYC 340
+ K +C C +VF +N LA+ + H +K ++C C + F +
Sbjct: 724 QAIH----TGKKPYKCNECGKVFT-QNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTT 778
Query: 341 HLDSH 345
H+ H
Sbjct: 779 HMAIH 783
Score = 105 bits (262), Expect = 3e-22
Identities = 134/548 (24%), Positives = 187/548 (34%), Gaps = 128/548 (23%)
Query: 779 KAHKCIFCGETFSTEVELQCHITTHS--KKYNCKFCSKAF--------HAIILL-EKHLR 827
K +KC CG+ F+ L H HS K Y C C K F H +I EK +
Sbjct: 255 KPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIHTGEKPYK 314
Query: 828 EKHC--VFD----AATENGTANGVPPMATKKAEPADLQG-------MLLKNPEAP----- 869
C VF AT G P + A +G L+ E P
Sbjct: 315 CHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKA-FRGHSNLTTHQLIHTGEKPFKCNE 373
Query: 870 -------NSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKK 922
NSH S + E Y C+ CG A+++ L H+ I GE
Sbjct: 374 CGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQ----TIHTGEK------ 423
Query: 923 AEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHS 982
+KCN C + F + L H + H G K Y C CG+ F L H+V H
Sbjct: 424 ------PYKCNECGKVFRYNSYLGRHRRVHTG-EKPYKCNECGKAFSMHSNLATHQVIH- 475
Query: 983 KSLDTGT----CRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIH 1038
TGT C C + H ++H + ++C C + + L H
Sbjct: 476 ----TGTKPFKCNECSKVFTQNSQLANHRRIHTGEK----PYKCNECGKAFSVRSSLTTH 527
Query: 1039 GTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLVKLDVNGLPYGLCAGCMAR 1098
H +K YKC C K F K L R
Sbjct: 528 QAIHSG----------------EKPYKCIECGKSFTQKSHL------------------R 553
Query: 1099 SANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGP--RKG 1156
S G G P +C EC F L H +V H P R
Sbjct: 554 SHRGIHSGEKP----------YKCNECGKVFAQTSQLARHWRV-HTGEKPYKCNDCGRAF 602
Query: 1157 TQTSPV-------PRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDS 1209
+ S + +K Y+C +C F + + H H E+ ++C C + F
Sbjct: 603 SDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEK--PYKCNECGKAFSM 660
Query: 1210 PAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFF 1269
+ L H + H+ E +KC C VF Q + L H G +K Y C++C + F
Sbjct: 661 HSNLTTHKVIHTGE---KPYKCNQCGKVFTQNSHLANHQRTHTG--EKPYRCNECGKAFS 715
Query: 1270 FQTELQNH 1277
++ L H
Sbjct: 716 VRSSLTTH 723
Score = 96.7 bits (239), Expect = 1e-19
Identities = 57/194 (29%), Positives = 85/194 (43%), Gaps = 29/194 (14%)
Query: 64 ESIYTCDHCQQDFESLADLTDHRA-------HRCPGDGDDDPQLSWVASSPSSKDVASPT 116
E Y C+ C + F ++LT H+ ++C G Q S +A+ +
Sbjct: 646 EKPYKCNECGKAFSMHSNLTTHKVIHTGEKPYKCNQCGKVFTQNSHLANHQRTHT----- 700
Query: 117 QMIGDGCDLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFK 176
GE+ PY C C K+F S L H+ IH+ K P+KC C ++F
Sbjct: 701 -----------GEK------PYRCNECGKAFSVRSSLTTHQAIHTGKKPYKCNECGKVFT 743
Query: 177 HKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSS 236
H ++HTG+K Y C EC AF L H+ H+ K +KC C + F +S+
Sbjct: 744 QNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTTHMAIHTGEKRYKCNECGKVFRQSSN 803
Query: 237 LQSHMQAHKKNKEH 250
L SH + H K +
Sbjct: 804 LASHHRMHTGEKPY 817
Score = 89.7 bits (221), Expect = 2e-17
Identities = 101/403 (25%), Positives = 149/403 (36%), Gaps = 44/403 (10%)
Query: 901 LQNHRLRD-HNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHY 959
+Q HR + H + R+KA +KCN C + F + L H + H G K Y
Sbjct: 227 VQTHRSKKYHELNHFSLLTQRRKANSCGKPYKCNECGKAFTQNSNLTSHRRIHSG-EKPY 285
Query: 960 MCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTG 1019
C CG+ F LT H+V H+ C C + H ++H +
Sbjct: 286 KCSECGKTFTVRSNLTIHQVIHTGE-KPYKCHECGKVFRHNSYLATHRRIHTGEK----P 340
Query: 1020 FRCVVCMQTVTSTLELKIHGTFHMQK------------LAGSSAASSPNGQGLQKLYKCA 1067
++C C + L H H + S S +K YKC
Sbjct: 341 YKCNECGKAFRGHSNLTTHQLIHTGEKPFKCNECGKLFTQNSHLISHWRIHTGEKPYKCN 400
Query: 1068 LCLKEFRSKQDLV---KLDVNGLPYGLCAGC-MARSANGQVGGLAPPEPADRPCAGLRCP 1123
C K F + L + PY C C N +G ++P +C
Sbjct: 401 ECGKAFSVRSSLAIHQTIHTGEKPY-KCNECGKVFRYNSYLGRHRRVHTGEKP---YKCN 456
Query: 1124 ECSVKFESAEDLESHMQVDHRDLTPETSG--PRKGTQTSPVPR-------KKTYQCIKCQ 1174
EC F +L +H QV H P + TQ S + +K Y+C +C
Sbjct: 457 ECGKAFSMHSNLATH-QVIHTGTKPFKCNECSKVFTQNSQLANHRRIHTGEKPYKCNECG 515
Query: 1175 MTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVC 1234
F + H A H E+ ++C C + F + L H HS E +KC C
Sbjct: 516 KAFSVRSSLTTHQAIHSGEK--PYKCIECGKSFTQKSHLRSHRGIHSGE---KPYKCNEC 570
Query: 1235 FTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNH 1277
VF Q ++L +H + VH E K Y C+ C + F ++ L H
Sbjct: 571 GKVFAQTSQLARH-WRVHTGE-KPYKCNDCGRAFSDRSSLTFH 611
Score = 43.5 bits (101), Expect = 0.001
Identities = 31/114 (27%), Positives = 49/114 (42%), Gaps = 7/114 (6%)
Query: 1166 KTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGM 1225
K Y+C +C F + H H E+ ++C C + F + L H + H+ E
Sbjct: 255 KPYKCNECGKAFTQNSNLTSHRRIHSGEKP--YKCSECGKTFTVRSNLTIHQVIHTGEK- 311
Query: 1226 GGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNHTM 1279
+KC C VF + L H +H E K Y C++C + F + L H +
Sbjct: 312 --PYKCHECGKVFRHNSYLATHR-RIHTGE-KPYKCNECGKAFRGHSNLTTHQL 361
>gi|38788288 zinc finger protein 160 [Homo sapiens]
Length = 818
Score = 186 bits (473), Expect = 9e-47
Identities = 174/677 (25%), Positives = 249/677 (36%), Gaps = 125/677 (18%)
Query: 135 GLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKY 194
G PY C C K+F + S L H +IHS + P+KC+ C + F + + H +HTG+K Y
Sbjct: 254 GKPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIHTGEKPY 313
Query: 195 HCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKS 254
CHEC F + +L H + H+ KP+KC C + F S+L +H H K
Sbjct: 314 KCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFRGHSNLTTHQLIHTGEK------ 367
Query: 255 EKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHI 314
F C+ C F+Q L H + + +C C + F ++L H
Sbjct: 368 -------PFKCNECGKLFTQNSHLISHWRIH----TGEKPYKCNECGKAFSVRSSLAIH- 415
Query: 315 HQAHANQK-HKCPMCPE--QFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSAT 371
H +K +KC C + +++S G + + + +P N G SM S
Sbjct: 416 QTIHTGEKPYKCNECGKVFRYNSYLGRHRRVHTGEKPYKCNE-------CGKAFSMHSNL 468
Query: 372 PDSSASVERGSTP---DSTLKPLRGQKKMRDDGQGWT-KVVYSCPYCSKRDFNSLAVLEI 427
+ G+ P + K ++ + + T + Y C C K F+ + L
Sbjct: 469 ATHQV-IHTGTKPFKCNECSKVFTQNSQLANHRRIHTGEKPYKCNECGKA-FSVRSSLTT 526
Query: 428 HLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPE 487
H +KP + C C S +L H R +H + CN C +
Sbjct: 527 HQAIHSGEKP---YKCIECGKSFTQKSHLRSH-RGIHSGE----------KPYKCNECGK 572
Query: 488 MFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAK 547
+FA + L H RV G + CN C F SSLT H Q H
Sbjct: 573 VFAQTSQLARHWRV---------HTGEKPYKCNDCGRAFSDRSSLTFH-QAIHTG----- 617
Query: 548 LESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVS 607
E P Y C C K+ +H N LA ++ + P
Sbjct: 618 -EKP-----------YKCHECG---------KVFRH------NSYLATHRRIHTGEKP-- 648
Query: 608 SDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQC 667
Y CN+C FS + TH +H + C QC
Sbjct: 649 ------------------------YKCNECGKAFSMHSNLTTHKVIHTG--EKPYKCNQC 682
Query: 668 KEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQE 727
+ F L H H T Y C C K FS L H Y C C +
Sbjct: 683 GKVFTQNSHLANHQRTH--TGEKPYRCNECGKAFSVRSSLTTHQAIHTGKKPYKCNECGK 740
Query: 728 VFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCG 787
VF + H + H+ EK YRCT C FR + L H+ H G K +KC CG
Sbjct: 741 VFTQNAHLANHRRI-HTGEKP-YRCTECGKAFRVRSSLTTHMA-IHTGE--KRYKCNECG 795
Query: 788 ETFSTEVELQCHITTHS 804
+ F L H H+
Sbjct: 796 KVFRQSSNLASHHRMHT 812
Score = 144 bits (363), Expect = 5e-34
Identities = 154/664 (23%), Positives = 235/664 (35%), Gaps = 131/664 (19%)
Query: 632 YPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTH 691
Y CN+C F+ + +H ++H + C +C + F + +L H +H T
Sbjct: 257 YKCNECGKAFTQNSNLTSHRRIHSGE--KPYKCSECGKTFTVRSNLTIHQVIH--TGEKP 312
Query: 692 YVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYR 751
Y C C K F L H Y C C + F ++ H + H+ EK ++
Sbjct: 313 YKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFRGHSNLTTHQLI-HTGEKP-FK 370
Query: 752 CTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHITTHS--KKYNC 809
C C F + + L + H + K +KC CG+ FS L H T H+ K Y C
Sbjct: 371 CNECGKLFTQNSHL---ISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTGEKPYKC 427
Query: 810 KFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAP 869
C K F L +H R
Sbjct: 428 NECGKVFRYNSYLGRHRR------------------------------------------ 445
Query: 870 NSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGS 929
V E Y C+ CG A++M L H++ +P
Sbjct: 446 ---------VHTGEKPYKCNECGKAFSMHSNLATHQVIHTGTKP---------------- 480
Query: 930 HKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGT 989
KCN CS+ F + L H + H G K Y C CG+ F +LT H+ HS
Sbjct: 481 FKCNECSKVFTQNSQLANHRRIHTG-EKPYKCNECGKAFSVRSSLTTHQAIHSGEKPYKC 539
Query: 990 CRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQK---- 1045
K Q H + H + + ++C C + T +L H H +
Sbjct: 540 IECGKSFTQK-----SHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARHWRVHTGEKPYK 594
Query: 1046 -----LAGSSAASSPNGQGL---QKLYKCALCLKEFRSKQDLV---KLDVNGLPYGLCAG 1094
A S +S Q + +K YKC C K FR L ++ PY C
Sbjct: 595 CNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPY-KCNE 653
Query: 1095 C-MARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGP 1153
C A S + + ++P +C +C F L +H +
Sbjct: 654 CGKAFSMHSNLTTHKVIHTGEKP---YKCNQCGKVFTQNSHLANHQR------------- 697
Query: 1154 RKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKL 1213
T T +K Y+C +C F + H A H ++ ++C C ++F A L
Sbjct: 698 ---THTG----EKPYRCNECGKAFSVRSSLTTHQAIHTGKK--PYKCNECGKVFTQNAHL 748
Query: 1214 LCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTE 1273
H H+ E ++C C F + L H+ A+H E K Y C++C + F +
Sbjct: 749 ANHRRIHTGE---KPYRCTECGKAFRVRSSLTTHM-AIHTGE-KRYKCNECGKVFRQSSN 803
Query: 1274 LQNH 1277
L +H
Sbjct: 804 LASH 807
Score = 140 bits (354), Expect = 6e-33
Identities = 154/627 (24%), Positives = 231/627 (36%), Gaps = 106/627 (16%)
Query: 480 FHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQA 539
+ CN C + F ++L H R+ G + C++C F S+LT H Q
Sbjct: 257 YKCNECGKAFTQNSNLTSHRRIH---------SGEKPYKCSECGKTFTVRSNLTIH-QVI 306
Query: 540 HCSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKS 599
H E P Y C C S L + I K K+
Sbjct: 307 HTG------EKP-----------YKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKA 349
Query: 600 KAEQSPVSSDVEVSSPKR--------QRLSASANSISN-----GE--YPCNQCDLKFSNF 644
S +++ + + ++ + + +++ IS+ GE Y CN+C FS
Sbjct: 350 FRGHSNLTTHQLIHTGEKPFKCNECGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVR 409
Query: 645 ESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSV 704
S H +H + C +C + F L +H VH T Y C C K FS
Sbjct: 410 SSLAIHQTIHTGE--KPYKCNECGKVFRYNSYLGRHRRVH--TGEKPYKCNECGKAFSMH 465
Query: 705 DDLQKHLLDMHTFVL-YHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEA 763
+L H + +HT + C C +VF + H + H+ EK Y+C C F +
Sbjct: 466 SNLATHQV-IHTGTKPFKCNECSKVFTQNSQLANHRRI-HTGEKP-YKCNECGKAFSVRS 522
Query: 764 DLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHITTHS--KKYNCKFCSKAFHAIIL 821
L H + H G K +KCI CG++F+ + L+ H HS K Y C C K F
Sbjct: 523 SLTTH-QAIHSGE--KPYKCIECGKSFTQKSHLRSHRGIHSGEKPYKCNECGKVFAQTSQ 579
Query: 822 LEKHLR----EK-----HCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAPNSH 872
L +H R EK C + + +K G + ++ NS+
Sbjct: 580 LARHWRVHTGEKPYKCNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRH----NSY 635
Query: 873 EASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKC 932
A+ + E Y C+ CG A++M L H++ I GE +KC
Sbjct: 636 LATHRRIHTGEKPYKCNECGKAFSMHSNLTTHKV----IHTGEK------------PYKC 679
Query: 933 NVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRI 992
N C + F + L H +TH G K Y C CG+ F +LT H+ H+ C
Sbjct: 680 NQCGKVFTQNSHLANHQRTHTG-EKPYRCNECGKAFSVRSSLTTHQAIHT-GKKPYKCNE 737
Query: 993 CKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAA 1052
C H ++H + +RC C + L H H
Sbjct: 738 CGKVFTQNAHLANHRRIHTGEK----PYRCTECGKAFRVRSSLTTHMAIHTG-------- 785
Query: 1053 SSPNGQGLQKLYKCALCLKEFRSKQDL 1079
+K YKC C K FR +L
Sbjct: 786 --------EKRYKCNECGKVFRQSSNL 804
Score = 125 bits (315), Expect = 2e-28
Identities = 84/305 (27%), Positives = 127/305 (41%), Gaps = 50/305 (16%)
Query: 64 ESIYTCDHCQQDFESLADLTDHRA-------HRCPGDGDDDPQLSWVASSPSSKDVASPT 116
E Y C+ C + F + LT H+A ++C G Q S + S
Sbjct: 506 EKPYKCNECGKAFSVRSSLTTHQAIHSGEKPYKCIECGKSFTQKSHLRSHRG-------- 557
Query: 117 QMIGDGCDLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFK 176
+ GE+ PY C C K F + S L RH ++H+ + P+KC C R F
Sbjct: 558 --------IHSGEK------PYKCNECGKVFAQTSQLARHWRVHTGEKPYKCNDCGRAFS 603
Query: 177 HKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSS 236
+ S H +HTG+K Y CHEC F + +L H + H+ KP+KC C + FS S+
Sbjct: 604 DRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFSMHSN 663
Query: 237 LQSHMQAHKKNK--------------EHLAKSEK-EAKKDDFMCDYCEDTFSQTEELEKH 281
L +H H K HLA ++ + + C+ C FS L H
Sbjct: 664 LTTHKVIHTGEKPYKCNQCGKVFTQNSHLANHQRTHTGEKPYRCNECGKAFSVRSSLTTH 723
Query: 282 VLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQAHANQK-HKCPMCPEQFSSVEGVYC 340
+ K +C C +VF +N LA+ + H +K ++C C + F +
Sbjct: 724 QAIH----TGKKPYKCNECGKVFT-QNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTT 778
Query: 341 HLDSH 345
H+ H
Sbjct: 779 HMAIH 783
Score = 105 bits (262), Expect = 3e-22
Identities = 134/548 (24%), Positives = 187/548 (34%), Gaps = 128/548 (23%)
Query: 779 KAHKCIFCGETFSTEVELQCHITTHS--KKYNCKFCSKAF--------HAIILL-EKHLR 827
K +KC CG+ F+ L H HS K Y C C K F H +I EK +
Sbjct: 255 KPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIHTGEKPYK 314
Query: 828 EKHC--VFD----AATENGTANGVPPMATKKAEPADLQG-------MLLKNPEAP----- 869
C VF AT G P + A +G L+ E P
Sbjct: 315 CHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKA-FRGHSNLTTHQLIHTGEKPFKCNE 373
Query: 870 -------NSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKK 922
NSH S + E Y C+ CG A+++ L H+ I GE
Sbjct: 374 CGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQ----TIHTGEK------ 423
Query: 923 AEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHS 982
+KCN C + F + L H + H G K Y C CG+ F L H+V H
Sbjct: 424 ------PYKCNECGKVFRYNSYLGRHRRVHTG-EKPYKCNECGKAFSMHSNLATHQVIH- 475
Query: 983 KSLDTGT----CRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIH 1038
TGT C C + H ++H + ++C C + + L H
Sbjct: 476 ----TGTKPFKCNECSKVFTQNSQLANHRRIHTGEK----PYKCNECGKAFSVRSSLTTH 527
Query: 1039 GTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLVKLDVNGLPYGLCAGCMAR 1098
H +K YKC C K F K L R
Sbjct: 528 QAIHSG----------------EKPYKCIECGKSFTQKSHL------------------R 553
Query: 1099 SANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGP--RKG 1156
S G G P +C EC F L H +V H P R
Sbjct: 554 SHRGIHSGEKP----------YKCNECGKVFAQTSQLARHWRV-HTGEKPYKCNDCGRAF 602
Query: 1157 TQTSPV-------PRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDS 1209
+ S + +K Y+C +C F + + H H E+ ++C C + F
Sbjct: 603 SDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEK--PYKCNECGKAFSM 660
Query: 1210 PAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFF 1269
+ L H + H+ E +KC C VF Q + L H G +K Y C++C + F
Sbjct: 661 HSNLTTHKVIHTGE---KPYKCNQCGKVFTQNSHLANHQRTHTG--EKPYRCNECGKAFS 715
Query: 1270 FQTELQNH 1277
++ L H
Sbjct: 716 VRSSLTTH 723
Score = 96.7 bits (239), Expect = 1e-19
Identities = 57/194 (29%), Positives = 85/194 (43%), Gaps = 29/194 (14%)
Query: 64 ESIYTCDHCQQDFESLADLTDHRA-------HRCPGDGDDDPQLSWVASSPSSKDVASPT 116
E Y C+ C + F ++LT H+ ++C G Q S +A+ +
Sbjct: 646 EKPYKCNECGKAFSMHSNLTTHKVIHTGEKPYKCNQCGKVFTQNSHLANHQRTHT----- 700
Query: 117 QMIGDGCDLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFK 176
GE+ PY C C K+F S L H+ IH+ K P+KC C ++F
Sbjct: 701 -----------GEK------PYRCNECGKAFSVRSSLTTHQAIHTGKKPYKCNECGKVFT 743
Query: 177 HKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSS 236
H ++HTG+K Y C EC AF L H+ H+ K +KC C + F +S+
Sbjct: 744 QNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTTHMAIHTGEKRYKCNECGKVFRQSSN 803
Query: 237 LQSHMQAHKKNKEH 250
L SH + H K +
Sbjct: 804 LASHHRMHTGEKPY 817
Score = 89.7 bits (221), Expect = 2e-17
Identities = 101/403 (25%), Positives = 149/403 (36%), Gaps = 44/403 (10%)
Query: 901 LQNHRLRD-HNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHY 959
+Q HR + H + R+KA +KCN C + F + L H + H G K Y
Sbjct: 227 VQTHRSKKYHELNHFSLLTQRRKANSCGKPYKCNECGKAFTQNSNLTSHRRIHSG-EKPY 285
Query: 960 MCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTG 1019
C CG+ F LT H+V H+ C C + H ++H +
Sbjct: 286 KCSECGKTFTVRSNLTIHQVIHTGE-KPYKCHECGKVFRHNSYLATHRRIHTGEK----P 340
Query: 1020 FRCVVCMQTVTSTLELKIHGTFHMQK------------LAGSSAASSPNGQGLQKLYKCA 1067
++C C + L H H + S S +K YKC
Sbjct: 341 YKCNECGKAFRGHSNLTTHQLIHTGEKPFKCNECGKLFTQNSHLISHWRIHTGEKPYKCN 400
Query: 1068 LCLKEFRSKQDLV---KLDVNGLPYGLCAGC-MARSANGQVGGLAPPEPADRPCAGLRCP 1123
C K F + L + PY C C N +G ++P +C
Sbjct: 401 ECGKAFSVRSSLAIHQTIHTGEKPY-KCNECGKVFRYNSYLGRHRRVHTGEKP---YKCN 456
Query: 1124 ECSVKFESAEDLESHMQVDHRDLTPETSG--PRKGTQTSPVPR-------KKTYQCIKCQ 1174
EC F +L +H QV H P + TQ S + +K Y+C +C
Sbjct: 457 ECGKAFSMHSNLATH-QVIHTGTKPFKCNECSKVFTQNSQLANHRRIHTGEKPYKCNECG 515
Query: 1175 MTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVC 1234
F + H A H E+ ++C C + F + L H HS E +KC C
Sbjct: 516 KAFSVRSSLTTHQAIHSGEK--PYKCIECGKSFTQKSHLRSHRGIHSGE---KPYKCNEC 570
Query: 1235 FTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNH 1277
VF Q ++L +H + VH E K Y C+ C + F ++ L H
Sbjct: 571 GKVFAQTSQLARH-WRVHTGE-KPYKCNDCGRAFSDRSSLTFH 611
Score = 43.5 bits (101), Expect = 0.001
Identities = 31/114 (27%), Positives = 49/114 (42%), Gaps = 7/114 (6%)
Query: 1166 KTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGM 1225
K Y+C +C F + H H E+ ++C C + F + L H + H+ E
Sbjct: 255 KPYKCNECGKAFTQNSNLTSHRRIHSGEKP--YKCSECGKTFTVRSNLTIHQVIHTGEK- 311
Query: 1226 GGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNHTM 1279
+KC C VF + L H +H E K Y C++C + F + L H +
Sbjct: 312 --PYKCHECGKVFRHNSYLATHR-RIHTGE-KPYKCNECGKAFRGHSNLTTHQL 361
>gi|49574543 zinc finger protein 616 [Homo sapiens]
Length = 781
Score = 186 bits (472), Expect = 1e-46
Identities = 171/698 (24%), Positives = 258/698 (36%), Gaps = 149/698 (21%)
Query: 134 TGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKK 193
T PY C C K+F R S L H+ +H+ ++C C ++F+ RH + HTG K
Sbjct: 209 TEKPYKCNECGKAFHRASLLTVHKVVHTRGKSYQCDVCGKIFRKNSYFVRHQRSHTGQKP 268
Query: 194 YHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAK 253
Y C+EC +FS+S HL +H + H+ KP+KC +C + FS L+ H H +
Sbjct: 269 YICNECGKSFSKSSHLAVHQRIHTGEKPYKCNLCGKSFSQRVHLRLHQTVHTGER----- 323
Query: 254 SEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAH 313
F C+ C TF ++ L H + + K +C C + F + L+ H
Sbjct: 324 --------PFKCNECGKTFKRSSNLTVHQVIH----AGKKPYKCDVCGKAFRHRSNLVCH 371
Query: 314 IHQAHANQKHKCPMCPEQFSSVEGVYCHLDSH--RQPDSSNHSVSPDPVLGSVASMSSAT 371
+++KC C + FS + H H +P N G V S S
Sbjct: 372 RRIHSGEKQYKCNECGKVFSKRSSLAVHRRIHTVEKPCKCNE-------CGKVFSKRS-- 422
Query: 372 PDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKT 431
S A +R T GQK Y C C K ++ + L +H +
Sbjct: 423 --SLAVHQRIHT---------GQK------------TYKCNKCGK-VYSKHSHLAVHWR- 457
Query: 432 IHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFAD 491
IH ++++ C C L H +++H + CN C ++F+
Sbjct: 458 IHTG--EKAYKCNECGKVFSIHSRLAAH-QRIHTGE----------KPYKCNECGKVFSQ 504
Query: 492 INSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESP 551
+ L H R+ G + C +C F S+ H ++ H E P
Sbjct: 505 HSRLAVHRRI---------HTGEKPYKCKECGKVFSDRSAFARH-RRIHTG------EKP 548
Query: 552 VVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVE 611
Y C C +F +LT H
Sbjct: 549 -----------YKCKEC--GKVFSQCSRLTVH---------------------------- 567
Query: 612 VSSPKRQRLSASANSISNGE--YPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKE 669
I +GE Y CN+C +S + H ++H + C +C +
Sbjct: 568 -------------RRIHSGEKPYKCNECGKVYSQYSHLVGHRRVHTG--EKPYKCHECGK 612
Query: 670 DFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVF 729
F+ +L +H +H T Y C C FS L+ H Y C C + F
Sbjct: 613 AFNQGSTLNRHQRIH--TGEKPYKCNQCGNSFSQRVHLRLHQTVHTGDRPYKCNECGKTF 670
Query: 730 DSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGET 789
++ H + H+ KK Y+C C FR + L V H + K +KCI CG+
Sbjct: 671 KRSSNLTAHQII-HAG-KKPYKCDECGKVFRHSSHL---VSHQRIHTGEKRYKCIECGKA 725
Query: 790 FSTEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKH 825
F L H HS K Y C C K+F L KH
Sbjct: 726 FGRLFSLSKHQRIHSGKKPYKCNECGKSFICRSGLTKH 763
Score = 164 bits (415), Expect = 5e-40
Identities = 181/772 (23%), Positives = 271/772 (35%), Gaps = 186/772 (24%)
Query: 188 HTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKN 247
H +K Y C+EC AF S L H + H++ KP+KC C + F S L H H +
Sbjct: 179 HIREKTYVCNECGKAFKASSSLINHQRIHTTEKPYKCNECGKAFHRASLLTVHKVVHTRG 238
Query: 248 KEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDE 307
K + CD C F + +H + +K + C C + F
Sbjct: 239 KS-------------YQCDVCGKIFRKNSYFVRH---QRSHTGQKPYI-CNECGKSFSKS 281
Query: 308 NTLLAHIHQAHANQK-HKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVAS 366
+ L H + H +K +KC +C + FS HL H+
Sbjct: 282 SHLAVH-QRIHTGEKPYKCNLCGKSFSQ----RVHLRLHQ-------------------- 316
Query: 367 MSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLE 426
+V G P + C C K F + L
Sbjct: 317 ----------TVHTGERP------------------------FKCNECGKT-FKRSSNLT 341
Query: 427 IHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCP 486
+H + IHA K + + C +C + NL H R++H + CN C
Sbjct: 342 VH-QVIHAGK--KPYKCDVCGKAFRHRSNLVCH-RRIHSGE----------KQYKCNECG 387
Query: 487 EMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSA 546
++F+ +SL H R+ CN+C F SSL H Q+ H
Sbjct: 388 KVFSKRSSLAVHRRIHTVEKPCK---------CNECGKVFSKRSSLAVH-QRIHTG---- 433
Query: 547 KLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPV 606
+ Y C C G + H+ H + E++
Sbjct: 434 -------------QKTYKCNKC------GKVYSKHSHLA--------VHWRIHTGEKAYK 466
Query: 607 SSDVEVSSPKRQRLSASANSISNGE--YPCNQCDLKFSNFESFQTHLKLHLELLLRKQAC 664
++ RL+A I GE Y CN+C FS H ++H + C
Sbjct: 467 CNECGKVFSIHSRLAAHQR-IHTGEKPYKCNECGKVFSQHSRLAVHRRIHTGE--KPYKC 523
Query: 665 PQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTL 724
+C + F + + +H +H T Y C+ C K FS L H Y C
Sbjct: 524 KECGKVFSDRSAFARHRRIH--TGEKPYKCKECGKVFSQCSRLTVHRRIHSGEKPYKCNE 581
Query: 725 CQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCI 784
C +V+ + H V H+ EK Y+C C F + + L +H + K +KC
Sbjct: 582 CGKVYSQYSHLVGHRRV-HTGEKP-YKCHECGKAFNQGSTLN---RHQRIHTGEKPYKCN 636
Query: 785 FCGETFSTEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENGTA 842
CG +FS V L+ H T H+ + Y C C K F + N TA
Sbjct: 637 QCGNSFSQRVHLRLHQTVHTGDRPYKCNECGKTFKR------------------SSNLTA 678
Query: 843 NGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQ 902
+ + A KK D G + ++ +SH S + E Y C CG A+ L
Sbjct: 679 HQIIH-AGKKPYKCDECGKVFRH----SSHLVSHQRIHTGEKRYKCIECGKAFGRLFSLS 733
Query: 903 NHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRG 954
H+ I G K +KCN C ++F +GL +H H G
Sbjct: 734 KHQ----RIHSG------------KKPYKCNECGKSFICRSGLTKHRIRHTG 769
Score = 155 bits (393), Expect = 2e-37
Identities = 143/611 (23%), Positives = 226/611 (36%), Gaps = 109/611 (17%)
Query: 137 PYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 196
PY C C KSF + S+L H++IH+ + P+KC C + F + H +HTG++ + C
Sbjct: 268 PYICNECGKSFSKSSHLAVHQRIHTGEKPYKCNLCGKSFSQRVHLRLHQTVHTGERPFKC 327
Query: 197 HECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEK 256
+EC F RS +L +H H+ KP+KC VC + F S+L H + H K+
Sbjct: 328 NECGKTFKRSSNLTVHQVIHAGKKPYKCDVCGKAFRHRSNLVCHRRIHSGEKQ------- 380
Query: 257 EAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQ 316
+ C+ C FS+ L H R EK +C C +VF ++L H +
Sbjct: 381 ------YKCNECGKVFSKRSSLAVH---RRIHTVEK-PCKCNECGKVFSKRSSLAVH-QR 429
Query: 317 AHANQK-HKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDSS 375
H QK +KC C + +S + HL H + + + + G V S+ S +
Sbjct: 430 IHTGQKTYKCNKCGKVYSK----HSHLAVHWRIHTGEKAYKCNE-CGKVFSIHSRLA-AH 483
Query: 376 ASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHAD 435
+ G P Y C C K F+ + L +H + +
Sbjct: 484 QRIHTGEKP------------------------YKCNECGK-VFSQHSRLAVHRRIHTGE 518
Query: 436 KPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINSL 495
KP + C+ C H R++H + C C ++F+ + L
Sbjct: 519 KP---YKCKECGKVFSDRSAFARH-RRIHTGE----------KPYKCKECGKVFSQCSRL 564
Query: 496 QEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQP 555
H R+ G + CN+C + S L H ++ H E P
Sbjct: 565 TVHRRI---------HSGEKPYKCNECGKVYSQYSHLVGH-RRVHTG------EKP---- 604
Query: 556 TQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSP 615
Y C C + GS L + I K S +++ + V +
Sbjct: 605 -------YKCHECGKAFNQGSTLNRHQRIHTGEKPYKCNQCGNSFSQRVHLRLHQTVHTG 657
Query: 616 KRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQE 675
R Y CN+C F + H +H + C +C + F
Sbjct: 658 DR-------------PYKCNECGKTFKRSSNLTAHQIIHAG--KKPYKCDECGKVFRHSS 702
Query: 676 SLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSI 735
L+ H +H T Y C C K F + L KH Y C C + F + +
Sbjct: 703 HLVSHQRIH--TGEKRYKCIECGKAFGRLFSLSKHQRIHSGKKPYKCNECGKSFICRSGL 760
Query: 736 QVHLAVKHSNE 746
H ++H+ E
Sbjct: 761 TKH-RIRHTGE 770
Score = 149 bits (375), Expect = 2e-35
Identities = 153/656 (23%), Positives = 234/656 (35%), Gaps = 115/656 (17%)
Query: 632 YPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTH 691
Y CN+C F H +H + C C + F ++H H T
Sbjct: 213 YKCNECGKAFHRASLLTVHKVVHTRG--KSYQCDVCGKIFRKNSYFVRHQRSH--TGQKP 268
Query: 692 YVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYR 751
Y+C C K FS L H Y C LC + F +V +++H V H+ E+ ++
Sbjct: 269 YICNECGKSFSKSSHLAVHQRIHTGEKPYKCNLCGKSFSQRVHLRLHQTV-HTGERP-FK 326
Query: 752 CTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHITTHS--KKYNC 809
C C F++ ++L VH + H G K +KC CG+ F L CH HS K+Y C
Sbjct: 327 CNECGKTFKRSSNLTVH-QVIHAGK--KPYKCDVCGKAFRHRSNLVCHRRIHSGEKQYKC 383
Query: 810 KFCSKAFHAIILLEKHLR----EKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKN 865
C K F L H R EK C N + +K+
Sbjct: 384 NECGKVFSKRSSLAVHRRIHTVEKPC---------KCNECGKVFSKR------------- 421
Query: 866 PEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEF 925
S A + + Y C+ CG Y+ L H I GE
Sbjct: 422 -----SSLAVHQRIHTGQKTYKCNKCGKVYSKHSHLAVH----WRIHTGEK--------- 463
Query: 926 IKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSL 985
++KCN C + F + L H + H G K Y C CG+ F L H+ H+
Sbjct: 464 ---AYKCNECGKVFSIHSRLAAHQRIHTGE-KPYKCNECGKVFSQHSRLAVHRRIHTGEK 519
Query: 986 DTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQK 1045
C+ C F H ++H + ++C C + + L +H H
Sbjct: 520 PY-KCKECGKVFSDRSAFARHRRIHTGEKP----YKCKECGKVFSQCSRLTVHRRIHSG- 573
Query: 1046 LAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLV---KLDVNGLPYGLCAGC-MARSAN 1101
+K YKC C K + LV ++ PY C C A +
Sbjct: 574 ---------------EKPYKCNECGKVYSQYSHLVGHRRVHTGEKPYK-CHECGKAFNQG 617
Query: 1102 GQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGPRKGTQTSP 1161
+ ++P +C +C F L H V D
Sbjct: 618 STLNRHQRIHTGEKP---YKCNQCGNSFSQRVHLRLHQTVHTGD---------------- 658
Query: 1162 VPRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHS 1221
+ Y+C +C TF+ + H H ++ ++C C ++F + L+ H H+
Sbjct: 659 ----RPYKCNECGKTFKRSSNLTAHQIIHAGKKP--YKCDECGKVFRHSSHLVSHQRIHT 712
Query: 1222 FEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNH 1277
E +KC C F + L +H G+ K Y C++C + F ++ L H
Sbjct: 713 GEKR---YKCIECGKAFGRLFSLSKHQRIHSGK--KPYKCNECGKSFICRSGLTKH 763
Score = 143 bits (360), Expect = 1e-33
Identities = 165/718 (22%), Positives = 260/718 (36%), Gaps = 116/718 (16%)
Query: 587 NHKNIPLAHS-----KKSKAEQSPVSS---DVEVSSPKRQRLSASANSISNGE-YPCNQC 637
N K +P+ H K+ + Q V + + +++S RL+ + G Y CN+
Sbjct: 107 NDKEVPVPHENNLTGKRDQHSQGDVENNHIENQLTSNFESRLAELQKVQTEGRLYECNET 166
Query: 638 DLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESC 697
+ +N H++ + C +C + F + SL+ H +H TT Y C C
Sbjct: 167 EKTGNNGCLVSPHIRE------KTYVCNECGKAFKASSSLINHQRIH--TTEKPYKCNEC 218
Query: 698 DKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNW 757
K F L H + Y C +C ++F K S V H+ +K Y C C
Sbjct: 219 GKAFHRASLLTVHKVVHTRGKSYQCDVCGKIF-RKNSYFVRHQRSHTGQKP-YICNECGK 276
Query: 758 DFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHITTHS--KKYNCKFCSKA 815
F K + L VH + H G K +KC CG++FS V L+ H T H+ + + C C K
Sbjct: 277 SFSKSSHLAVH-QRIHTGE--KPYKCNLCGKSFSQRVHLRLHQTVHTGERPFKCNECGKT 333
Query: 816 FHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAPNSHEAS 875
F + N T + V A KK D+ G ++ S+
Sbjct: 334 F------------------KRSSNLTVHQV-IHAGKKPYKCDVCGKAFRH----RSNLVC 370
Query: 876 EDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVC 935
+ + E Y C+ CG ++ L HR + ++ KCN C
Sbjct: 371 HRRIHSGEKQYKCNECGKVFSKRSSLAVHR----------------RIHTVEKPCKCNEC 414
Query: 936 SRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKM 995
+ F + L H + H G K Y C CG+ + L H H+ C C
Sbjct: 415 GKVFSKRSSLAVHQRIHTG-QKTYKCNKCGKVYSKHSHLAVHWRIHTGE-KAYKCNECGK 472
Query: 996 PLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQ------KLAG- 1048
H ++H + ++C C + + L +H H K G
Sbjct: 473 VFSIHSRLAAHQRIHTGEK----PYKCNECGKVFSQHSRLAVHRRIHTGEKPYKCKECGK 528
Query: 1049 -----SSAASSPNGQGLQKLYKCALCLKEFRSKQDLV---KLDVNGLPYGLCAGC-MARS 1099
S+ A +K YKC C K F L ++ PY C C S
Sbjct: 529 VFSDRSAFARHRRIHTGEKPYKCKECGKVFSQCSRLTVHRRIHSGEKPY-KCNECGKVYS 587
Query: 1100 ANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGPRKGTQT 1159
+ G ++P +C EC F L H ++
Sbjct: 588 QYSHLVGHRRVHTGEKP---YKCHECGKAFNQGSTLNRHQRIH----------------- 627
Query: 1160 SPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIE 1219
+K Y+C +C +F +++H H + ++C C + F + L H I
Sbjct: 628 ---TGEKPYKCNQCGNSFSQRVHLRLHQTVHTGDR--PYKCNECGKTFKRSSNLTAHQII 682
Query: 1220 HSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNH 1277
H+ + +KC C VF ++ L H +H E K Y C +C + F L H
Sbjct: 683 HAGK---KPYKCDECGKVFRHSSHLVSH-QRIHTGE-KRYKCIECGKAFGRLFSLSKH 735
Score = 137 bits (346), Expect = 5e-32
Identities = 172/754 (22%), Positives = 255/754 (33%), Gaps = 148/754 (19%)
Query: 490 ADINSLQEHIRVSHCGPNANPSDGNNA-----------FFCNQCSMGFLTESSLTEHIQQ 538
A++ +Q R+ C N GNN + CN+C F SSL H Q+
Sbjct: 149 AELQKVQTEGRLYEC--NETEKTGNNGCLVSPHIREKTYVCNECGKAFKASSSLINH-QR 205
Query: 539 AHCSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKK 598
H + E P Y C C + S+L + K + H+ +
Sbjct: 206 IHTT------EKP-----------YKCNECGKAFHRASLLTVHK----------VVHT-R 237
Query: 599 SKAEQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELL 658
K+ Q V + + R S Y CN+C FS H ++H
Sbjct: 238 GKSYQCDVCGKIFRKNSYFVRHQRS--HTGQKPYICNECGKSFSKSSHLAVHQRIHTG-- 293
Query: 659 LRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFV 718
+ C C + F + L H TVH T + C C K F +L H +
Sbjct: 294 EKPYKCNLCGKSFSQRVHLRLHQTVH--TGERPFKCNECGKTFKRSSNLTVHQVIHAGKK 351
Query: 719 LYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPA 778
Y C +C + F + ++ H + HS EK+ Y+C C F K + L VH + + P
Sbjct: 352 PYKCDVCGKAFRHRSNLVCHRRI-HSGEKQ-YKCNECGKVFSKRSSLAVHRRIHTVEKPC 409
Query: 779 KAHKCIFCGETFSTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFDAA 836
KC CG+ FS L H I T K Y C C K + KH H
Sbjct: 410 ---KCNECGKVFSKRSSLAVHQRIHTGQKTYKCNKCGKVY------SKH---SHLAVHWR 457
Query: 837 TENGTANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYT 896
G +KA + G + + +S A+ + E Y C+ CG ++
Sbjct: 458 IHTG----------EKAYKCNECGKVF----SIHSRLAAHQRIHTGEKPYKCNECGKVFS 503
Query: 897 MEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPA 956
L HR I GE +KC C + F + H + H G
Sbjct: 504 QHSRLAVHR----RIHTGEK------------PYKCKECGKVFSDRSAFARHRRIHTG-E 546
Query: 957 KHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNS 1016
K Y C CG+ F LT H+ HS C C + H ++H +
Sbjct: 547 KPYKCKECGKVFSQCSRLTVHRRIHSGE-KPYKCNECGKVYSQYSHLVGHRRVHTGEK-- 603
Query: 1017 LTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSK 1076
++C C + L H H +K YKC C F +
Sbjct: 604 --PYKCHECGKAFNQGSTLNRHQRIHTG----------------EKPYKCNQCGNSFSQR 645
Query: 1077 QDL---VKLDVNGLPY--GLCAGCMARSANGQVGGLAPPEPADRPCAGLRCPECSVKFES 1131
L + PY C RS+N L + +C EC F
Sbjct: 646 VHLRLHQTVHTGDRPYKCNECGKTFKRSSN-----LTAHQIIHAGKKPYKCDECGKVFRH 700
Query: 1132 AEDLESHMQVDHRDLTPETSGPRKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHM 1191
+ L SH ++ +K Y+CI+C F + H H
Sbjct: 701 SSHLVSHQRIH--------------------TGEKRYKCIECGKAFGRLFSLSKHQRIHS 740
Query: 1192 IEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGM 1225
++ ++C C + F + L H I H+ E +
Sbjct: 741 GKK--PYKCNECGKSFICRSGLTKHRIRHTGESL 772
Score = 133 bits (334), Expect = 1e-30
Identities = 150/633 (23%), Positives = 229/633 (36%), Gaps = 121/633 (19%)
Query: 405 TKVVYSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLH 464
T+ Y C C K F+ ++L +H K +H +S+ C +C ++ N + +
Sbjct: 209 TEKPYKCNECGKA-FHRASLLTVH-KVVHTRG--KSYQCDVC----GKIFRKNSYFVRHQ 260
Query: 465 KNHAYPVMQFGNISAFHCNYCPEMFADINSLQEHIRV---------SHCGPNANPS---- 511
++H + CN C + F+ + L H R+ + CG + +
Sbjct: 261 RSHT-------GQKPYICNECGKSFSKSSHLAVHQRIHTGEKPYKCNLCGKSFSQRVHLR 313
Query: 512 ------DGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVYSC 565
G F CN+C F S+LT H Q + + Y C
Sbjct: 314 LHQTVHTGERPFKCNECGKTFKRSSNLTVH------------------QVIHAGKKPYKC 355
Query: 566 PYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASAN 625
C + H++ + H + E+ ++ KR L+
Sbjct: 356 DVCGKA--------------FRHRSNLVCHRRIHSGEKQYKCNECGKVFSKRSSLAVHRR 401
Query: 626 SISNGEYPC--NQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTV 683
I E PC N+C FS S H ++H K C +C + + L H +
Sbjct: 402 -IHTVEKPCKCNECGKVFSKRSSLAVHQRIHTGQKTYK--CNKCGKVYSKHSHLAVHWRI 458
Query: 684 HYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKH 743
H T Y C C K FS L H Y C C +VF + VH + H
Sbjct: 459 H--TGEKAYKCNECGKVFSIHSRLAAHQRIHTGEKPYKCNECGKVFSQHSRLAVHRRI-H 515
Query: 744 SNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHITTH 803
+ EK Y+C C F +D +H + K +KC CG+ FS L H H
Sbjct: 516 TGEKP-YKCKECGKVF---SDRSAFARHRRIHTGEKPYKCKECGKVFSQCSRLTVHRRIH 571
Query: 804 S--KKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQGM 861
S K Y C C K + L H R G P + A QG
Sbjct: 572 SGEKPYKCNECGKVYSQYSHLVGHRR-------------VHTGEKPYKCHECGKAFNQGS 618
Query: 862 LLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRP---GEDDG 918
L N H+ + E Y C+ CG +++ V L+ H+ RP E
Sbjct: 619 TL------NRHQR----IHTGEKPYKCNQCGNSFSQRVHLRLHQTVHTGDRPYKCNECGK 668
Query: 919 SRKKAEFI---------KGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFP 969
+ K++ + K +KC+ C + F + L H + H G K Y C CG+ F
Sbjct: 669 TFKRSSNLTAHQIIHAGKKPYKCDECGKVFRHSSHLVSHQRIHTGE-KRYKCIECGKAFG 727
Query: 970 SLLTLTEHKVTHS-----KSLDTGTCRICKMPL 997
L +L++H+ HS K + G IC+ L
Sbjct: 728 RLFSLSKHQRIHSGKKPYKCNECGKSFICRSGL 760
Score = 117 bits (294), Expect = 5e-26
Identities = 112/483 (23%), Positives = 178/483 (36%), Gaps = 86/483 (17%)
Query: 67 YTCDHCQQDFESLADLTDHRA-------HRCPGDGDDDPQLSWVASSPSSKDVASPTQ-- 117
Y CD C + F ++L HR ++C G + S +A V P +
Sbjct: 353 YKCDVCGKAFRHRSNLVCHRRIHSGEKQYKCNECGKVFSKRSSLAVHRRIHTVEKPCKCN 412
Query: 118 ----MIGDGCDLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSR 173
+ L + + Y C C K + + S+L H +IH+ + +KC C +
Sbjct: 413 ECGKVFSKRSSLAVHQRIHTGQKTYKCNKCGKVYSKHSHLAVHWRIHTGEKAYKCNECGK 472
Query: 174 LFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSS 233
+F H ++HTG+K Y C+EC FS+ L +H + H+ KP+KC C + FS
Sbjct: 473 VFSIHSRLAAHQRIHTGEKPYKCNECGKVFSQHSRLAVHRRIHTGEKPYKCKECGKVFSD 532
Query: 234 TSSLQSHMQAHKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKA 293
S+ H + H K + C C FSQ L H R EK
Sbjct: 533 RSAFARHRRIHTGEK-------------PYKCKECGKVFSQCSRLTVH---RRIHSGEK- 575
Query: 294 DLQCIHCPEVFVDENTLLAHIHQAHANQK-HKCPMCPEQFSSVEGVYCHLDSHRQPDSSN 352
+C C +V+ + L+ H + H +K +KC C + F+ + H H
Sbjct: 576 PYKCNECGKVYSQYSHLVGH-RRVHTGEKPYKCHECGKAFNQGSTLNRHQRIH------- 627
Query: 353 HSVSPDPVLGSVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCP 412
T + + S LR + + + Y C
Sbjct: 628 ------------------TGEKPYKCNQCGNSFSQRVHLRLHQTVHTGDR-----PYKCN 664
Query: 413 YCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVM 472
C K F + L H + IHA K + + C C +L H +++H
Sbjct: 665 ECGK-TFKRSSNLTAH-QIIHAGK--KPYKCDECGKVFRHSSHLVSH-QRIHTGE----- 714
Query: 473 QFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSL 532
+ C C + F + SL +H R+ G + CN+C F+ S L
Sbjct: 715 -----KRYKCIECGKAFGRLFSLSKHQRI---------HSGKKPYKCNECGKSFICRSGL 760
Query: 533 TEH 535
T+H
Sbjct: 761 TKH 763
Score = 63.2 bits (152), Expect = 2e-09
Identities = 41/154 (26%), Positives = 62/154 (40%), Gaps = 15/154 (9%)
Query: 64 ESIYTCDHCQQDFESLADLTDHRAHRCPGDGDDDPQLSWVASSPSSKDVASPTQMIGDGC 123
E Y C+ C F L R H+ GD + + + + Q+I G
Sbjct: 630 EKPYKCNQCGNSFSQRVHL---RLHQTVHTGDRPYKCNECGKTFKRSSNLTAHQIIHAGK 686
Query: 124 DLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDR 183
PY C C K F S+L H++IH+ + +KC C + F S +
Sbjct: 687 K------------PYKCDECGKVFRHSSHLVSHQRIHTGEKRYKCIECGKAFGRLFSLSK 734
Query: 184 HIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHS 217
H ++H+G K Y C+EC +F L H H+
Sbjct: 735 HQRIHSGKKPYKCNECGKSFICRSGLTKHRIRHT 768
>gi|194018469 zinc finger protein 546 [Homo sapiens]
Length = 836
Score = 180 bits (457), Expect = 7e-45
Identities = 173/701 (24%), Positives = 260/701 (37%), Gaps = 129/701 (18%)
Query: 137 PYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 196
PY C C K+F R+ L+ H IH+ + P++C C + F+ H ++H+G K Y C
Sbjct: 244 PYKCMECGKAFCRVGDLRVHHTIHAGERPYECKECGKAFRLHYHLTEHQRIHSGVKPYEC 303
Query: 197 HECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEK 256
EC AFSR L++H H+ +P++C C + F L H + H +
Sbjct: 304 KECGKAFSRVRDLRVHQTIHAGERPYECKECGKAFRLHYQLTEHQRIHTGER-------- 355
Query: 257 EAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQ 316
+ C C TF +++H+ + +C C + F + L+ H +
Sbjct: 356 -----PYECKVCGKTF----RVQRHISQHQKIHTGVKPYKCNECGKAFSHGSYLVQH-QK 405
Query: 317 AHANQK-HKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDSS 375
H +K ++C C + FS + L HR+
Sbjct: 406 IHTGEKPYECKECGKSFS----FHAELARHRR---------------------------- 433
Query: 376 ASVERGSTPDSTL---KPLRGQKKMRDDGQGWT-KVVYSCPYCSKRDFNSLAVLEIHLKT 431
+ G P K R Q ++ + T + Y C C K F L +HL+T
Sbjct: 434 --IHTGEKPYECRECGKAFRLQTELTRHHRTHTGEKPYECKECGKA-FICGYQLTLHLRT 490
Query: 432 IHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFAD 491
+ P + C+ C + + Y+L +H R +H + CN C + F
Sbjct: 491 HTGEIP---YECKECGKTFSSRYHLTQHYR-IHTGE----------KPYICNECGKAFRL 536
Query: 492 INSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESP 551
L H R+ C + C +C F+ + H Q+ H S +
Sbjct: 537 QGELTRHHRIHTC---------EKPYECKECGKAFIHSNQFISH-QRIHTSEST------ 580
Query: 552 VVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVE 611
Y C C IF LT+H K + P ++ KA E
Sbjct: 581 -----------YICKEC--GKIFSRRYNLTQHFKIHTGEKPYICNECGKA----FRFQTE 623
Query: 612 VSSPKRQRLSASANSISNGE--YPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKE 669
++ R I GE Y C +C F H ++H + C +C +
Sbjct: 624 LTQHHR---------IHTGEKPYKCTECGKAFIRSTHLTQHHRIHTG--EKPYECTECGK 672
Query: 670 DFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVL-YHCTLCQEV 728
F L QH H T Y+C C F L H +HT L Y C C +
Sbjct: 673 TFSRHYHLTQHHRGH--TGEKPYICNECGNAFICSYRLTLH-QRIHTGELPYECKECGKT 729
Query: 729 FDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGE 788
F + + H + H+ EK Y C C FR +A+L +H + K +KC CG+
Sbjct: 730 FSRRYHLTQHFRL-HTGEKP-YSCKECGNAFRLQAEL---TRHHIVHTGEKPYKCKECGK 784
Query: 789 TFSTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLR 827
FS EL H I T K Y CK C KAF L H R
Sbjct: 785 AFSVNSELTRHHRIHTGEKPYQCKECGKAFIRSDQLTLHQR 825
Score = 149 bits (375), Expect = 2e-35
Identities = 166/654 (25%), Positives = 238/654 (36%), Gaps = 111/654 (16%)
Query: 646 SFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVD 705
S H K+H + C +C++ F Q L+QHL +H T Y C C K F V
Sbjct: 203 SHPLHPKIHARE--KSYECKECRKAFRQQSYLIQHLRIH--TGERPYKCMECGKAFCRVG 258
Query: 706 DLQKHLLDMHTFVL----YHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRK 761
DL+ H HT Y C C + F + H + HS K Y C C F +
Sbjct: 259 DLRVH----HTIHAGERPYECKECGKAFRLHYHLTEHQRI-HSGVKP-YECKECGKAFSR 312
Query: 762 EADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCH--ITTHSKKYNCKFCSKAFHAI 819
DL+VH + H G + ++C CG+ F +L H I T + Y CK C K F
Sbjct: 313 VRDLRVH-QTIHAGE--RPYECKECGKAFRLHYQLTEHQRIHTGERPYECKVCGKTFR-- 367
Query: 820 ILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDV 879
+++H+ + + GV P + A G S+ +
Sbjct: 368 --VQRHISQHQKIH---------TGVKPYKCNECGKAFSHG----------SYLVQHQKI 406
Query: 880 DASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTF 939
E Y C CG +++ L HR I GE ++C C + F
Sbjct: 407 HTGEKPYECKECGKSFSFHAELARHR----RIHTGEKP------------YECRECGKAF 450
Query: 940 FSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQS 999
+ L H +TH G K Y C CG+ F LT H TH+ + C+ C S
Sbjct: 451 RLQTELTRHHRTHTGE-KPYECKECGKAFICGYQLTLHLRTHTGEIPY-ECKECGKTFSS 508
Query: 1000 EEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQ------KLAGSSAAS 1053
+H ++H + + C C + EL H H K G +
Sbjct: 509 RYHLTQHYRIHTGEKPYI----CNECGKAFRLQGELTRHHRIHTCEKPYECKECGKAFIH 564
Query: 1054 SPNGQGLQKL------YKCALCLKEFRSKQDLV---KLDVNGLPYGLCAGC-MARSANGQ 1103
S Q++ Y C C K F + +L K+ PY +C C A +
Sbjct: 565 SNQFISHQRIHTSESTYICKECGKIFSRRYNLTQHFKIHTGEKPY-ICNECGKAFRFQTE 623
Query: 1104 VGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGPRKGTQTSPVP 1163
+ ++P +C EC F + L H HR T E
Sbjct: 624 LTQHHRIHTGEKP---YKCTECGKAFIRSTHLTQH----HRIHTGE-------------- 662
Query: 1164 RKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFE 1223
K Y+C +C TF + H H E+ + C C F +L H H+ E
Sbjct: 663 --KPYECTECGKTFSRHYHLTQHHRGHTGEKP--YICNECGNAFICSYRLTLHQRIHTGE 718
Query: 1224 GMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNH 1277
++C C F + L QH F +H E K Y C +C F Q EL H
Sbjct: 719 L---PYECKECGKTFSRRYHLTQH-FRLHTGE-KPYSCKECGNAFRLQAELTRH 767
Score = 129 bits (324), Expect = 2e-29
Identities = 173/769 (22%), Positives = 258/769 (33%), Gaps = 153/769 (19%)
Query: 432 IHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFAD 491
IHA ++S+ C+ C + L +H+R +H + C C + F
Sbjct: 210 IHAR--EKSYECKECRKAFRQQSYLIQHLR-IHTGER----------PYKCMECGKAFCR 256
Query: 492 INSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESP 551
+ L+ H + G + C +C F LTEH Q+ H V
Sbjct: 257 VGDLRVHHTIHA---------GERPYECKECGKAFRLHYHLTEH-QRIHSGV-------- 298
Query: 552 VVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVE 611
+ Y C C + F + L H + P + KA + +
Sbjct: 299 ---------KPYECKECGKA--FSRVRDLRVHQTIHAGERPYECKECGKAFR------LH 341
Query: 612 VSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDF 671
+ QR+ Y C C F H K+H + + C +C + F
Sbjct: 342 YQLTEHQRIHTGERP-----YECKVCGKTFRVQRHISQHQKIHTGV--KPYKCNECGKAF 394
Query: 672 DSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDS 731
L+QH +H T Y C+ C K FS +L +H Y C C + F
Sbjct: 395 SHGSYLVQHQKIH--TGEKPYECKECGKSFSFHAELARHRRIHTGEKPYECRECGKAFRL 452
Query: 732 KVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFS 791
+ + H H+ EK Y C C F L +H++ +H G ++C CG+TFS
Sbjct: 453 QTELTRHHRT-HTGEKP-YECKECGKAFICGYQLTLHLR-THTGEIP--YECKECGKTFS 507
Query: 792 TEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMA 849
+ L H H+ K Y C C KAF L +H R C P
Sbjct: 508 SRYHLTQHYRIHTGEKPYICNECGKAFRLQGELTRHHRIHTCE-------------KPYE 554
Query: 850 TKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDH 909
K+ A + ++ S + SE Y C CG ++ L H
Sbjct: 555 CKECGKAFIH----------SNQFISHQRIHTSESTYICKECGKIFSRRYNLTQH----F 600
Query: 910 NIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFP 969
I GE + CN C + F + L +H + H G K Y C CG+ F
Sbjct: 601 KIHTGEKP------------YICNECGKAFRFQTELTQHHRIHTGE-KPYKCTECGKAFI 647
Query: 970 SLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTV 1029
LT+H H+ C C +H + H + + C C
Sbjct: 648 RSTHLTQHHRIHTGEKPY-ECTECGKTFSRHYHLTQHHRGHTGEKPYI----CNECGNAF 702
Query: 1030 TSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLV---KLDVNG 1086
+ L +H H +L Y+C C K F + L +L
Sbjct: 703 ICSYRLTLHQRIHTGELP----------------YECKECGKTFSRRYHLTQHFRLHTGE 746
Query: 1087 LPYGLCAGC-MARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRD 1145
PY C C A ++ ++P +C EC F +L H HR
Sbjct: 747 KPYS-CKECGNAFRLQAELTRHHIVHTGEKP---YKCKECGKAFSVNSELTRH----HRI 798
Query: 1146 LTPETSGPRKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEE 1194
T E K YQC +C F ++ +H NH+ EE
Sbjct: 799 HTGE----------------KPYQCKECGKAFIRSDQLTLHQRNHISEE 831
Score = 126 bits (316), Expect = 2e-28
Identities = 118/520 (22%), Positives = 187/520 (35%), Gaps = 104/520 (20%)
Query: 137 PYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 196
PY C+ C KSF + L RH +IH+ + P++C C + F+ + RH + HTG+K Y C
Sbjct: 412 PYECKECGKSFSFHAELARHRRIHTGEKPYECRECGKAFRLQTELTRHHRTHTGEKPYEC 471
Query: 197 HECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEK 256
EC AF L +HL+TH+ P++C C + FSS L H + H K
Sbjct: 472 KECGKAFICGYQLTLHLRTHTGEIPYECKECGKTFSSRYHLTQHYRIHTGEK-------- 523
Query: 257 EAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQ 316
++C+ C F EL +H H + + +C C + F+ N ++H
Sbjct: 524 -----PYICNECGKAFRLQGELTRH----HRIHTCEKPYECKECGKAFIHSNQFISHQRI 574
Query: 317 AHANQKHKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDSSA 376
+ + C C + FS + H H
Sbjct: 575 HTSESTYICKECGKIFSRRYNLTQHFKIH------------------------------- 603
Query: 377 SVERGSTPDSTLKPLRGQKKMRDDGQGWT-KVVYSCPYCSKRDFNSLAVLEIHLKTIHAD 435
+ E+ + K R Q ++ + T + Y C C K S + + H IH
Sbjct: 604 TGEKPYICNECGKAFRFQTELTQHHRIHTGEKPYKCTECGKAFIRSTHLTQHH--RIHTG 661
Query: 436 KPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINSL 495
++ + C C + Y+L +H H+ H + CN C F L
Sbjct: 662 --EKPYECTECGKTFSRHYHLTQH----HRGHT-------GEKPYICNECGNAFICSYRL 708
Query: 496 QEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQP 555
H R+ G + C +C F LT+H + H E P
Sbjct: 709 TLHQRI---------HTGELPYECKECGKTFSRRYHLTQHF-RLHTG------EKP---- 748
Query: 556 TQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSP 615
YSC C N+ F +LT+H +I K K ++ + V
Sbjct: 749 -------YSCKECGNA--FRLQAELTRH------HIVHTGEKPYKCKECGKAFSVNSELT 793
Query: 616 KRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHL 655
+ R+ Y C +C F + H + H+
Sbjct: 794 RHHRIHTGEK-----PYQCKECGKAFIRSDQLTLHQRNHI 828
Score = 113 bits (282), Expect = 1e-24
Identities = 109/482 (22%), Positives = 175/482 (36%), Gaps = 93/482 (19%)
Query: 64 ESIYTCDHCQQDFESLADLTDHRAHRCPGDGDDDPQLSWVASSPSSKDVASPTQMIGDGC 123
E Y C C + F +LT H HR + P + G
Sbjct: 438 EKPYECRECGKAFRLQTELTRH--HR-----------THTGEKPYECKECGKAFICGYQL 484
Query: 124 DLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDR 183
L L G +PY C+ C K+F +L +H +IH+ + P+ C C + F+ + R
Sbjct: 485 TLHLRTHTGE--IPYECKECGKTFSSRYHLTQHYRIHTGEKPYICNECGKAFRLQGELTR 542
Query: 184 HIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQA 243
H ++HT +K Y C EC AF S+ H + H+S + C C + FS +L H +
Sbjct: 543 HHRIHTCEKPYECKECGKAFIHSNQFISHQRIHTSESTYICKECGKIFSRRYNLTQHFKI 602
Query: 244 HKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEV 303
H K ++C+ C F EL +H H + + +C C +
Sbjct: 603 HTGEK-------------PYICNECGKAFRFQTELTQH----HRIHTGEKPYKCTECGKA 645
Query: 304 FVDENTLLAHIHQAHANQK-HKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLG 362
F+ L H H+ H +K ++C C + FS + HL H + H+ +
Sbjct: 646 FIRSTHLTQH-HRIHTGEKPYECTECGKTFSR----HYHLTQHHR----GHTGEKPYICN 696
Query: 363 SV--ASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFN 420
A + S + G P Y C C K F+
Sbjct: 697 ECGNAFICSYRLTLHQRIHTGELP------------------------YECKECGK-TFS 731
Query: 421 SLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAF 480
L H + +KP ++C+ C ++ + L + + H H +
Sbjct: 732 RRYHLTQHFRLHTGEKP---YSCKECGNA----FRLQAELTRHHIVHT-------GEKPY 777
Query: 481 HCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAH 540
C C + F+ + L H R+ G + C +C F+ LT H Q+ H
Sbjct: 778 KCKECGKAFSVNSELTRHHRI---------HTGEKPYQCKECGKAFIRSDQLTLH-QRNH 827
Query: 541 CS 542
S
Sbjct: 828 IS 829
Score = 78.6 bits (192), Expect = 4e-14
Identities = 33/84 (39%), Positives = 47/84 (55%)
Query: 137 PYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 196
PY C+ C +F + L RH +H+ + P+KC C + F RH ++HTG+K Y C
Sbjct: 748 PYSCKECGNAFRLQAELTRHHIVHTGEKPYKCKECGKAFSVNSELTRHHRIHTGEKPYQC 807
Query: 197 HECEAAFSRSDHLKIHLKTHSSSK 220
EC AF RSD L +H + H S +
Sbjct: 808 KECGKAFIRSDQLTLHQRNHISEE 831
Score = 43.9 bits (102), Expect = 0.001
Identities = 32/121 (26%), Positives = 53/121 (43%), Gaps = 19/121 (15%)
Query: 1171 IKCQMTFENEREIQIHVANHM-IEEGINH-------------ECKLCNQMFDSPAKLLCH 1216
++C+ FE + Q+ + M I++ I+H ECK C + F + L+ H
Sbjct: 176 LQCKHEFERQERHQMGCVSQMLIQKQISHPLHPKIHAREKSYECKECRKAFRQQSYLIQH 235
Query: 1217 LIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQN 1276
L H+ E +KC C F + L+ H +H E + Y+C +C + F L
Sbjct: 236 LRIHTGE---RPYKCMECGKAFCRVGDLRVH-HTIHAGE-RPYECKECGKAFRLHYHLTE 290
Query: 1277 H 1277
H
Sbjct: 291 H 291
>gi|22095393 zinc finger protein 420 [Homo sapiens]
Length = 688
Score = 179 bits (453), Expect = 2e-44
Identities = 160/686 (23%), Positives = 249/686 (36%), Gaps = 143/686 (20%)
Query: 134 TGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKK 193
T PY C+ C K+F R S+L +H+ IH+ + P++C C + F H +LHTG+K
Sbjct: 135 TEKPYKCKECGKAFRRASHLTQHQSIHTGEKPYECKQCGKAFSRDSQLSLHQRLHTGEKP 194
Query: 194 YHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAK 253
Y C EC AF++S L +H + H+ KP+KC C + F +S L H + H K
Sbjct: 195 YACKECGKAFTQSSQLILHHRIHTGEKPYKCEECGKAFIRSSQLTRHQKVHTGEK----- 249
Query: 254 SEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADL-QCIHCPEVFVDENTLLA 312
+ C C F+Q + LT H +L L +C C +VF + L+
Sbjct: 250 --------PYECKECGKAFTQNSQ-----LTLHQRLHTGEKLYECKECRKVFTQLSQLIL 296
Query: 313 HIHQAHANQKHKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSATP 372
H + ++C C + F + GS S
Sbjct: 297 HKRIHTGEKPYECKECGKAF---------------------------ICGSQLSQHQ--- 326
Query: 373 DSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTI 432
+ G P Y C C R F ++L H +
Sbjct: 327 ----KIHNGEKP------------------------YECKECG-RAFIRGSLLMQHQRIH 357
Query: 433 HADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADI 492
+KP + C+ C + L +H +++H N + C C +MF+
Sbjct: 358 TGEKP---YKCEECGKAFIRGSQLTQH-QRIHTNE----------KPYECKECGKMFSHG 403
Query: 493 NSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPV 552
+ L +H R+ G + C +C F S LT H Q+ H E P
Sbjct: 404 SQLTQHQRI---------HTGEKPYQCKECGKAFNRGSLLTRH-QRIHTG------EKP- 446
Query: 553 VQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEV 612
Y C C + GS L + I K KS S ++ +
Sbjct: 447 ----------YECKECGKTFSRGSELTQHERIHTGEKPYECKECGKSFIRGSQLTQHQRI 496
Query: 613 SSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFD 672
+ ++ Y C +C + F+ H +LH + C +C + F
Sbjct: 497 HTGEK-------------PYECKECRMAFTQSSHLSQHQRLHTG--EKPYVCNECGKAFA 541
Query: 673 SQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSK 732
L+QH +H T Y C+ C K F L +H Y C C + F
Sbjct: 542 RGLLLIQHQRIH--TGEKPYQCKECGKAFIRGSQLTQHQRIHTGEKPYECKECGKAFSHG 599
Query: 733 VSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFST 792
+ +H + H+ EK Y C C F + + L +H + K ++C CG+ F+
Sbjct: 600 SQLTLHQRI-HTGEKP-YECRECRKAFTQSSHLS---RHQRIHTGEKPYQCKECGKAFTR 654
Query: 793 EVELQCHITTH--SKKYNCKFCSKAF 816
+L H H K + K C F
Sbjct: 655 GSQLTQHQRIHISEKSFEYKECGIDF 680
Score = 139 bits (349), Expect = 2e-32
Identities = 152/621 (24%), Positives = 226/621 (36%), Gaps = 107/621 (17%)
Query: 664 CPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVL-YHC 722
C +C + F L QH ++H T Y C+ C K FS L H +HT Y C
Sbjct: 141 CKECGKAFRRASHLTQHQSIH--TGEKPYECKQCGKAFSRDSQLSLHQR-LHTGEKPYAC 197
Query: 723 TLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHK 782
C + F + +H + H+ EK Y+C C F + + L H K H G K ++
Sbjct: 198 KECGKAFTQSSQLILHHRI-HTGEKP-YKCEECGKAFIRSSQLTRHQK-VHTGE--KPYE 252
Query: 783 CIFCGETFSTEVELQCHITTHS--KKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENG 840
C CG+ F+ +L H H+ K Y CK C K F + L H R
Sbjct: 253 CKECGKAFTQNSQLTLHQRLHTGEKLYECKECRKVFTQLSQLILHKR------------- 299
Query: 841 TANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVL 900
G P K+ A + G L + + E Y C CG A+ L
Sbjct: 300 IHTGEKPYECKECGKAFICGSQL----------SQHQKIHNGEKPYECKECGRAFIRGSL 349
Query: 901 LQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYM 960
L H+ I GE +KC C + F + L +H + H K Y
Sbjct: 350 LMQHQ----RIHTGEKP------------YKCEECGKAFIRGSQLTQHQRIHTNE-KPYE 392
Query: 961 CPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGF 1020
C CG+ F LT+H+ H+ C+ C H ++H + +
Sbjct: 393 CKECGKMFSHGSQLTQHQRIHTGEKPY-QCKECGKAFNRGSLLTRHQRIHTGEKP----Y 447
Query: 1021 RCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLV 1080
C C +T + EL H H +K Y+C C K F L
Sbjct: 448 ECKECGKTFSRGSELTQHERIHTG----------------EKPYECKECGKSFIRGSQLT 491
Query: 1081 ---KLDVNGLPYGLCAGC-MARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLE 1136
++ PY C C MA + + + ++P C EC F L
Sbjct: 492 QHQRIHTGEKPYE-CKECRMAFTQSSHLSQHQRLHTGEKPYV---CNECGKAFARGLLLI 547
Query: 1137 SHMQVDHRDLTPETSGPRKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEGI 1196
H ++ + K YQC +C F ++ H H E+
Sbjct: 548 QHQRIHTGE--------------------KPYQCKECGKAFIRGSQLTQHQRIHTGEKP- 586
Query: 1197 NHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQED 1256
+ECK C + F ++L H H+ E ++C C F Q++ L +H +H E
Sbjct: 587 -YECKECGKAFSHGSQLTLHQRIHTGE---KPYECRECRKAFTQSSHLSRH-QRIHTGE- 640
Query: 1257 KIYDCSQCPQKFFFQTELQNH 1277
K Y C +C + F ++L H
Sbjct: 641 KPYQCKECGKAFTRGSQLTQH 661
Score = 134 bits (337), Expect = 6e-31
Identities = 147/593 (24%), Positives = 217/593 (36%), Gaps = 93/593 (15%)
Query: 626 SISNGE--YPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTV 683
SI GE Y C QC FS H +LH + AC +C + F L+ H +
Sbjct: 159 SIHTGEKPYECKQCGKAFSRDSQLSLHQRLHTGE--KPYACKECGKAFTQSSQLILHHRI 216
Query: 684 HYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVL-YHCTLCQEVFDSKVSIQVHLAVK 742
H T Y CE C K F L +H +HT Y C C + F + +H +
Sbjct: 217 H--TGEKPYKCEECGKAFIRSSQLTRHQ-KVHTGEKPYECKECGKAFTQNSQLTLHQRL- 272
Query: 743 HSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHITT 802
H+ EK +Y C C F + + L +H K H G K ++C CG+ F +L H
Sbjct: 273 HTGEK-LYECKECRKVFTQLSQLILH-KRIHTGE--KPYECKECGKAFICGSQLSQHQKI 328
Query: 803 HS--KKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQG 860
H+ K Y CK C +AF LL +H R G P ++ A ++G
Sbjct: 329 HNGEKPYECKECGRAFIRGSLLMQHQR-------------IHTGEKPYKCEECGKAFIRG 375
Query: 861 MLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSR 920
L + + +E Y C CG ++ L H+ I GE
Sbjct: 376 SQLTQHQR----------IHTNEKPYECKECGKMFSHGSQLTQHQ----RIHTGEKP--- 418
Query: 921 KKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVT 980
++C C + F + L H + H G K Y C CG+ F LT+H+
Sbjct: 419 ---------YQCKECGKAFNRGSLLTRHQRIHTGE-KPYECKECGKTFSRGSELTQHERI 468
Query: 981 HSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGT 1040
H+ C+ C + +H ++H + + C C T + L H
Sbjct: 469 HTGEKPY-ECKECGKSFIRGSQLTQHQRIHTGEKP----YECKECRMAFTQSSHLSQHQR 523
Query: 1041 FHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLV---KLDVNGLPYGLCAGCMA 1097
H +K Y C C K F L+ ++ PY C C
Sbjct: 524 LHTG----------------EKPYVCNECGKAFARGLLLIQHQRIHTGEKPYQ-CKECGK 566
Query: 1098 RSANG-QVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGPRKG 1156
G Q+ ++P C EC F L H ++ + E RK
Sbjct: 567 AFIRGSQLTQHQRIHTGEKP---YECKECGKAFSHGSQLTLHQRIHTGEKPYECRECRKA 623
Query: 1157 -TQTSPVPR-------KKTYQCIKCQMTFENEREIQIHVANHMIEEGINH-EC 1200
TQ+S + R +K YQC +C F ++ H H+ E+ + EC
Sbjct: 624 FTQSSHLSRHQRIHTGEKPYQCKECGKAFTRGSQLTQHQRIHISEKSFEYKEC 676
Score = 130 bits (326), Expect = 1e-29
Identities = 162/734 (22%), Positives = 263/734 (35%), Gaps = 126/734 (17%)
Query: 349 DSSNHSVSPDPVLGSVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVV 408
DS+ + D +L + +++ S S + + S +T + Q +M D +
Sbjct: 24 DSAQRDLYRDVMLENYSNLVSLDLPSRCASKDLSPEKNTYETELSQWEMSDRLEN----- 78
Query: 409 YSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQ--ICLDSMPTLYNLNEHVRKLHKN 466
C + NS LE K + Q+ + Q I D M +++N + ++ + +
Sbjct: 79 -----CDLEESNSRDYLEAKGKMEKQQENQKEYFRQGMIIYDKM-SIFNQHTYLSQHSRC 132
Query: 467 HAYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGF 526
H+ + C C + F R SH + + G + C QC F
Sbjct: 133 HSTE-------KPYKCKECGKAFR---------RASHLTQHQSIHTGEKPYECKQCGKAF 176
Query: 527 LTESSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKE 586
+S L+ H Q+ H E P Y+C C + S L L I
Sbjct: 177 SRDSQLSLH-QRLHTG------EKP-----------YACKECGKAFTQSSQLILHHRIHT 218
Query: 587 NHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFES 646
K K+ S ++ +V + ++ Y C +C F+
Sbjct: 219 GEKPYKCEECGKAFIRSSQLTRHQKVHTGEKP-------------YECKECGKAFTQNSQ 265
Query: 647 FQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDD 706
H +LH L + C +C++ F L+ H +H T Y C+ C K F
Sbjct: 266 LTLHQRLHTGEKLYE--CKECRKVFTQLSQLILHKRIH--TGEKPYECKECGKAFICGSQ 321
Query: 707 LQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQ 766
L +H + Y C C F + H + H+ EK Y+C C F + + L
Sbjct: 322 LSQHQKIHNGEKPYECKECGRAFIRGSLLMQHQRI-HTGEKP-YKCEECGKAFIRGSQL- 378
Query: 767 VHVKHSHLGNPAKAHKCIFCGETFSTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEK 824
+H + K ++C CG+ FS +L H I T K Y CK C KAF+ LL +
Sbjct: 379 --TQHQRIHTNEKPYECKECGKMFSHGSQLTQHQRIHTGEKPYQCKECGKAFNRGSLLTR 436
Query: 825 HLRE---------KHC--VFDAATE----NGTANGVPPMATKKAEPADLQGMLLKNPE-- 867
H R K C F +E G P K+ + ++G L +
Sbjct: 437 HQRIHTGEKPYECKECGKTFSRGSELTQHERIHTGEKPYECKECGKSFIRGSQLTQHQRI 496
Query: 868 ----------------APNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNI 911
+SH + + E Y C+ CG A+ +LL H+ I
Sbjct: 497 HTGEKPYECKECRMAFTQSSHLSQHQRLHTGEKPYVCNECGKAFARGLLLIQHQ----RI 552
Query: 912 RPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSL 971
GE ++C C + F + L +H + H G K Y C CG+ F
Sbjct: 553 HTGEK------------PYQCKECGKAFIRGSQLTQHQRIHTG-EKPYECKECGKAFSHG 599
Query: 972 LTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTS 1031
LT H+ H+ CR C+ H ++H + ++C C + T
Sbjct: 600 SQLTLHQRIHTGE-KPYECRECRKAFTQSSHLSRHQRIHTGEK----PYQCKECGKAFTR 654
Query: 1032 TLELKIHGTFHMQK 1045
+L H H+ +
Sbjct: 655 GSQLTQHQRIHISE 668
Score = 121 bits (303), Expect = 5e-27
Identities = 149/624 (23%), Positives = 215/624 (34%), Gaps = 116/624 (18%)
Query: 405 TKVVYSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLH 464
T+ Y C C K F + L H +KP + C+ C + L+ H R LH
Sbjct: 135 TEKPYKCKECGKA-FRRASHLTQHQSIHTGEKPYE---CKQCGKAFSRDSQLSLHQR-LH 189
Query: 465 KNHAYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSM 524
+ C C + F + L H R+ G + C +C
Sbjct: 190 TGE----------KPYACKECGKAFTQSSQLILHHRIH---------TGEKPYKCEECGK 230
Query: 525 GFLTESSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHI 584
F+ S LT H Q+ H E P Y C C + S L L + +
Sbjct: 231 AFIRSSQLTRH-QKVHTG------EKP-----------YECKECGKAFTQNSQLTLHQRL 272
Query: 585 KENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNF 644
K +K + S + + + ++ Y C +C F
Sbjct: 273 HTGEKLYECKECRKVFTQLSQLILHKRIHTGEKP-------------YECKECGKAFICG 319
Query: 645 ESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSV 704
H K+H + C +C F L+QH +H T Y CE C K F
Sbjct: 320 SQLSQHQKIHNGE--KPYECKECGRAFIRGSLLMQHQRIH--TGEKPYKCEECGKAFIRG 375
Query: 705 DDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEAD 764
L +H Y C C ++F + H + H+ EK Y+C C F + +
Sbjct: 376 SQLTQHQRIHTNEKPYECKECGKMFSHGSQLTQHQRI-HTGEKP-YQCKECGKAFNRGSL 433
Query: 765 LQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCH--ITTHSKKYNCKFCSKAFHAIILL 822
L +H + K ++C CG+TFS EL H I T K Y CK C K+F L
Sbjct: 434 L---TRHQRIHTGEKPYECKECGKTFSRGSELTQHERIHTGEKPYECKECGKSFIRGSQL 490
Query: 823 EKHLRE---------KHCVFDAATENGTAN-------GVPPMATKKAEPADLQGMLLKNP 866
+H R K C A T++ + G P + A +G+LL
Sbjct: 491 TQHQRIHTGEKPYECKECRM-AFTQSSHLSQHQRLHTGEKPYVCNECGKAFARGLLL--- 546
Query: 867 EAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKA--E 924
+ E Y C CG A+ L H+ I GE K+
Sbjct: 547 -------IQHQRIHTGEKPYQCKECGKAFIRGSQLTQHQ----RIHTGEKPYECKECGKA 595
Query: 925 FIKGS--------------HKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPS 970
F GS ++C C + F + L H + H G K Y C CG+ F
Sbjct: 596 FSHGSQLTLHQRIHTGEKPYECRECRKAFTQSSHLSRHQRIHTGE-KPYQCKECGKAFTR 654
Query: 971 LLTLTEHKVTH--SKSLDTGTCRI 992
LT+H+ H KS + C I
Sbjct: 655 GSQLTQHQRIHISEKSFEYKECGI 678
Score = 112 bits (279), Expect = 3e-24
Identities = 77/287 (26%), Positives = 122/287 (42%), Gaps = 40/287 (13%)
Query: 63 DESIYTCDHCQQDFESLADLTDH-RAHRCPGDGDDDPQLSWVASSPSSKDVASPTQMIGD 121
+E Y C C + F + LT H R H G+ Q + + + + Q I
Sbjct: 387 NEKPYECKECGKMFSHGSQLTQHQRIH----TGEKPYQCKECGKAFNRGSLLTRHQRIHT 442
Query: 122 GCDLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSR 181
G PY C+ C K+F R S L +HE+IH+ + P++C C + F
Sbjct: 443 G------------EKPYECKECGKTFSRGSELTQHERIHTGEKPYECKECGKSFIRGSQL 490
Query: 182 DRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHM 241
+H ++HTG+K Y C EC AF++S HL H + H+ KP+ C C + F+ L H
Sbjct: 491 TQHQRIHTGEKPYECKECRMAFTQSSHLSQHQRLHTGEKPYVCNECGKAFARGLLLIQHQ 550
Query: 242 QAHKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCP 301
+ H K + C C F + +L +H + EK +C C
Sbjct: 551 RIHTGEK-------------PYQCKECGKAFIRGSQLTQH---QRIHTGEK-PYECKECG 593
Query: 302 EVFVDENTLLAHIHQAHANQK-HKCPMCPEQFSSVEGVYCHLDSHRQ 347
+ F + L H + H +K ++C C + F+ HL H++
Sbjct: 594 KAFSHGSQLTLH-QRIHTGEKPYECRECRKAFTQSS----HLSRHQR 635
Score = 111 bits (277), Expect = 5e-24
Identities = 143/647 (22%), Positives = 223/647 (34%), Gaps = 126/647 (19%)
Query: 637 CDLKFSNFESF-QTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCE 695
CDL+ SN + + K+ + +K+ Q +D QH + S H C
Sbjct: 79 CDLEESNSRDYLEAKGKMEKQQENQKEYFRQGMIIYDKMSIFNQHTYL-----SQHSRCH 133
Query: 696 SCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTAC 755
S +K Y C C + F + H ++ H+ EK Y C C
Sbjct: 134 STEKP-------------------YKCKECGKAFRRASHLTQHQSI-HTGEKP-YECKQC 172
Query: 756 NWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCH--ITTHSKKYNCKFCS 813
F +++ L +H + H G K + C CG+ F+ +L H I T K Y C+ C
Sbjct: 173 GKAFSRDSQLSLH-QRLHTGE--KPYACKECGKAFTQSSQLILHHRIHTGEKPYKCEECG 229
Query: 814 KAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAPNSHE 873
KAF L +H + G P K+ A Q NS
Sbjct: 230 KAFIRSSQLTRHQK-------------VHTGEKPYECKECGKAFTQ----------NSQL 266
Query: 874 ASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCN 933
+ E +Y C C +T L H+ I GE ++C
Sbjct: 267 TLHQRLHTGEKLYECKECRKVFTQLSQLILHK----RIHTGEKP------------YECK 310
Query: 934 VCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRIC 993
C + F + L +H + H G K Y C CG F L +H+ H+ C C
Sbjct: 311 ECGKAFICGSQLSQHQKIHNGE-KPYECKECGRAFIRGSLLMQHQRIHTGEKPY-KCEEC 368
Query: 994 KMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAAS 1053
+ +H ++H + + + C C + + +L H H
Sbjct: 369 GKAFIRGSQLTQHQRIHTNEKP----YECKECGKMFSHGSQLTQHQRIHTG--------- 415
Query: 1054 SPNGQGLQKLYKCALCLKEFRSKQDLVK---LDVNGLPYGLCAGCMARSANGQVGGLAPP 1110
+K Y+C C K F L + + PY C C + G L
Sbjct: 416 -------EKPYQCKECGKAFNRGSLLTRHQRIHTGEKPYE-CKECGKTFSRGSE--LTQH 465
Query: 1111 EPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGPRKGTQTSPVPRKKTYQC 1170
E C EC F L H ++ + K Y+C
Sbjct: 466 ERIHTGEKPYECKECGKSFIRGSQLTQHQRIHTGE--------------------KPYEC 505
Query: 1171 IKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFK 1230
+C+M F + H H E+ + C C + F L+ H H+ E ++
Sbjct: 506 KECRMAFTQSSHLSQHQRLHTGEK--PYVCNECGKAFARGLLLIQHQRIHTGE---KPYQ 560
Query: 1231 CPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNH 1277
C C F++ ++L QH +H E K Y+C +C + F ++L H
Sbjct: 561 CKECGKAFIRGSQLTQH-QRIHTGE-KPYECKECGKAFSHGSQLTLH 605
Score = 105 bits (263), Expect = 2e-22
Identities = 73/265 (27%), Positives = 115/265 (43%), Gaps = 38/265 (14%)
Query: 30 GEPECDQKTSRALEDRNSVTSQEERNEDDEDMEDESIYTCDHCQQDFESLADLTDH-RAH 88
GE + K R S +Q ER E Y C C + F + LT H R H
Sbjct: 443 GEKPYECKECGKTFSRGSELTQHERIHTGEKP-----YECKECGKSFIRGSQLTQHQRIH 497
Query: 89 RCPGDGDDDPQLSWVASSPSSKDVASPTQMIGDGCDLGLGEEEGGTGLPYPCQFCDKSFI 148
G+ + + +A + SS + L GE+ PY C C K+F
Sbjct: 498 T--GEKPYECKECRMAFTQSSH--------LSQHQRLHTGEK------PYVCNECGKAFA 541
Query: 149 RLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRSDH 208
R L +H++IH+ + P++C C + F +H ++HTG+K Y C EC AFS
Sbjct: 542 RGLLLIQHQRIHTGEKPYQCKECGKAFIRGSQLTQHQRIHTGEKPYECKECGKAFSHGSQ 601
Query: 209 LKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEKEAKKDDFMCDYC 268
L +H + H+ KP++C C++ F+ +S L H + H K + C C
Sbjct: 602 LTLHQRIHTGEKPYECRECRKAFTQSSHLSRHQRIHTGEK-------------PYQCKEC 648
Query: 269 EDTFSQTEELEKHVLTRHPQLSEKA 293
F++ +L +H + +SEK+
Sbjct: 649 GKAFTRGSQLTQH---QRIHISEKS 670
Score = 84.0 bits (206), Expect = 9e-16
Identities = 38/101 (37%), Positives = 54/101 (53%)
Query: 137 PYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 196
PY C+ C K+F S L H++IH+ + P++C C + F RH ++HTG+K Y C
Sbjct: 586 PYECKECGKAFSHGSQLTLHQRIHTGEKPYECRECRKAFTQSSHLSRHQRIHTGEKPYQC 645
Query: 197 HECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSL 237
EC AF+R L H + H S K F+ C FS S +
Sbjct: 646 KECGKAFTRGSQLTQHQRIHISEKSFEYKECGIDFSHGSQV 686
>gi|55769537 zinc finger protein 658 [Homo sapiens]
Length = 1059
Score = 176 bits (446), Expect = 1e-43
Identities = 168/717 (23%), Positives = 270/717 (37%), Gaps = 123/717 (17%)
Query: 143 CDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAA 202
C KSF R ++L +H++ HS + ++ C++ F +H + G K Y C+EC A
Sbjct: 389 CRKSFYRKAHLIQHQRPHSGEKTYQYEECAKSFCSSSHPIQHPGTYVGFKLYECNECGKA 448
Query: 203 FSRSDHLKIHLKTHSSSKPFKCTVCKRGFSST----SSLQSHMQ----------AHKKNK 248
F ++ +L HL+ H+ KP C R + S + M+ +H K
Sbjct: 449 FCQNSNLSKHLRIHTKEKPCDNNGCGRSYKSPLIGHQKTDAEMELCGGSEYGKTSHLKGH 508
Query: 249 EHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDEN 308
+ + EK + C C TFS+T L H + EK +C+ C + F +
Sbjct: 509 QRILMGEK-----PYECIECGKTFSKTSHLRAH---QRIHTGEK-PYECVECEKTFSHKT 559
Query: 309 TLLAHIHQAHANQK-HKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASM 367
L H + H +K ++C C + F+ + H H
Sbjct: 560 HLSVH-QRVHTGEKPYECNDCGKSFTYNSALRAHQRIH---------------------- 596
Query: 368 SSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEI 427
+ P + E+ +S LR ++ + Y C C R F ++VL+
Sbjct: 597 TGEKPYECSDCEKTFAHNSA---LRAHHRIHTG-----EKPYECNECG-RSFAHISVLKA 647
Query: 428 HLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPE 487
H + +KP + + C + N +R + H + C+ C +
Sbjct: 648 HQRIHTGEKPYECNEC-------GRSFTYNSALRAHQRIHT-------GRKPYECSDCEK 693
Query: 488 MFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAK 547
FA ++L+ H R+ G + CN+C F S+L H
Sbjct: 694 TFAHNSALKIHQRI---------HTGEKPYECNECEKTFAHNSALRAH------------ 732
Query: 548 LESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVS 607
Q + ++Y C C + + L + I K + K+ +++S +S
Sbjct: 733 ------QNIHTGEKLYECSECGKTFFQKTRLSTHRRIHTGEKPYECSKCGKTFSQKSYLS 786
Query: 608 SDVEVSSPKR-------------QRLSASANSISNGE--YPCNQCDLKFSNFESFQTHLK 652
+ + ++ + I GE Y CNQC FS H +
Sbjct: 787 GHERIHTGEKPYECNVCGKTFVYKAALIVHQRIHTGEKPYECNQCGKTFSQRTHLCAHQR 846
Query: 653 LHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLL 712
+H + C +C + F +L H +H T Y C C K FS L+ HL
Sbjct: 847 IHTG--EKPYECNECGKTFADNSALRAHHRIH--TGEKPYECNDCGKTFSKTSHLRAHLR 902
Query: 713 DMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHS 772
Y C+ C + F K + H V H+ EK Y C C F + L+VH +
Sbjct: 903 TRSGEKPYECSECGKTFSEKSYVSAHQRV-HTGEKP-YECNVCGKPFAHNSTLRVH-QRI 959
Query: 773 HLGNPAKAHKCIFCGETFSTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLR 827
H G K+++C CG+TFS + L H I T K Y C C KAF L H R
Sbjct: 960 HTGE--KSYECNDCGKTFSQKSHLSAHQRIHTGEKPYECNECGKAFAQNSTLRVHQR 1014
Score = 173 bits (438), Expect = 1e-42
Identities = 161/693 (23%), Positives = 255/693 (36%), Gaps = 153/693 (22%)
Query: 64 ESIYTCDHCQQDFESLADLTDHRAHRCPGDGDDDPQLSWVASSPSSKDVASPTQMIGDGC 123
E Y C C + F + L RAH+ G+ + + S K S Q + G
Sbjct: 515 EKPYECIECGKTFSKTSHL---RAHQRIHTGEKPYECVECEKTFSHKTHLSVHQRVHTG- 570
Query: 124 DLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDR 183
PY C C KSF S L+ H++IH+ + P++C+ C + F H +
Sbjct: 571 -----------EKPYECNDCGKSFTYNSALRAHQRIHTGEKPYECSDCEKTFAHNSALRA 619
Query: 184 HIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQA 243
H ++HTG+K Y C+EC +F+ LK H + H+ KP++C C R F+ S+L++H +
Sbjct: 620 HHRIHTGEKPYECNECGRSFAHISVLKAHQRIHTGEKPYECNECGRSFTYNSALRAHQRI 679
Query: 244 HKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEV 303
H K + C CE TF+ L+ H + EK +C C +
Sbjct: 680 HTGRK-------------PYECSDCEKTFAHNSALKIH---QRIHTGEK-PYECNECEKT 722
Query: 304 FVDENTLLAHIHQAHANQKHKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGS 363
F + L AH + + ++C C + F + H H P S
Sbjct: 723 FAHNSALRAHQNIHTGEKLYECSECGKTFFQKTRLSTHRRIH---------TGEKPYECS 773
Query: 364 VASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLA 423
+ + + ER T + KP Y C C K F A
Sbjct: 774 KCGKTFSQKSYLSGHERIHTGE---KP------------------YECNVCGK-TFVYKA 811
Query: 424 VLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCN 483
L +H + +KP + C C + +L H +++H + CN
Sbjct: 812 ALIVHQRIHTGEKP---YECNQCGKTFSQRTHLCAH-QRIHTGE----------KPYECN 857
Query: 484 YCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSV 543
C + FAD ++L+ H R+ G + CN C F S L H++
Sbjct: 858 ECGKTFADNSALRAHHRI---------HTGEKPYECNDCGKTFSKTSHLRAHLR------ 902
Query: 544 GSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQ 603
T+S + Y C C K+ +E+
Sbjct: 903 ------------TRSGEKPYECSEC----------------------------GKTFSEK 922
Query: 604 SPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQA 663
S VS+ V + ++ Y CN C F++ + + H ++H +
Sbjct: 923 SYVSAHQRVHTGEK-------------PYECNVCGKPFAHNSTLRVHQRIHTG--EKSYE 967
Query: 664 CPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCT 723
C C + F + L H +H T Y C C K F+ L+ H Y C
Sbjct: 968 CNDCGKTFSQKSHLSAHQRIH--TGEKPYECNECGKAFAQNSTLRVHQRIHTGEKPYECD 1025
Query: 724 LCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACN 756
C + F K +++VH H+ EK + ACN
Sbjct: 1026 ECGKTFVRKAALRVHHTRMHTREKTL----ACN 1054
Score = 172 bits (435), Expect = 2e-42
Identities = 200/881 (22%), Positives = 322/881 (36%), Gaps = 148/881 (16%)
Query: 156 HEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKT 215
+ ++H ++C F K + + TG + ++CE FS+S +H KT
Sbjct: 287 YNKVHMAMTHYECNERGINFSRKSPLTQSQRTITGWSAFESNKCEENFSQSSAHIVHQKT 346
Query: 216 HSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQT 275
+ K + C +H + H ++K +L S++ K C +F +
Sbjct: 347 QAGDKFGEHNECTDALYQKLDFTAHQRIHTEDKFYL--SDEHGK--------CRKSFYRK 396
Query: 276 EELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQAHANQKHKCPMCPEQFSSV 335
L +H + P EK Q C + F + + H + ++C C + F
Sbjct: 397 AHLIQH---QRPHSGEKT-YQYEECAKSFCSSSHPIQHPGTYVGFKLYECNECGKAFCQN 452
Query: 336 EGVYCHLDSH-RQPDSSNHSVS---PDPVLGSVASMSSATPDSSASVERGSTPDSTLKP- 390
+ HL H ++ N+ P++G + A + E G T S LK
Sbjct: 453 SNLSKHLRIHTKEKPCDNNGCGRSYKSPLIGH--QKTDAEMELCGGSEYGKT--SHLKGH 508
Query: 391 ---LRGQKKMR--DDGQGWTKV--------------VYSCPYCSKRDFNSLAVLEIHLKT 431
L G+K + G+ ++K Y C C K F+ L +H +
Sbjct: 509 QRILMGEKPYECIECGKTFSKTSHLRAHQRIHTGEKPYECVECEK-TFSHKTHLSVHQRV 567
Query: 432 IHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFAD 491
+KP + C C S L H +++H + C+ C + FA
Sbjct: 568 HTGEKP---YECNDCGKSFTYNSALRAH-QRIHTGE----------KPYECSDCEKTFAH 613
Query: 492 INSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESP 551
++L+ H R+ G + CN+C F S L H Q+ H E P
Sbjct: 614 NSALRAHHRI---------HTGEKPYECNECGRSFAHISVLKAH-QRIHTG------EKP 657
Query: 552 VVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVE 611
Y C C S + S L+ + I K + +K+ A S +
Sbjct: 658 -----------YECNECGRSFTYNSALRAHQRIHTGRKPYECSDCEKTFAHNSALKIHQR 706
Query: 612 VSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDF 671
+ + ++ Y CN+C+ F++ + + H +H L + C +C + F
Sbjct: 707 IHTGEK-------------PYECNECEKTFAHNSALRAHQNIHTGEKLYE--CSECGKTF 751
Query: 672 DSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDS 731
+ L H +H T Y C C K FS L H Y C +C + F
Sbjct: 752 FQKTRLSTHRRIH--TGEKPYECSKCGKTFSQKSYLSGHERIHTGEKPYECNVCGKTFVY 809
Query: 732 KVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFS 791
K ++ VH + H+ EK Y C C F + L H + H G K ++C CG+TF+
Sbjct: 810 KAALIVHQRI-HTGEKP-YECNQCGKTFSQRTHLCAH-QRIHTGE--KPYECNECGKTFA 864
Query: 792 TEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMA 849
L+ H I T K Y C C K F L HLR T +G P
Sbjct: 865 DNSALRAHHRIHTGEKPYECNDCGKTFSKTSHLRAHLR-------------TRSGEKPYE 911
Query: 850 TKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDH 909
+ G ++H+ V E Y C++CG + L+ H+
Sbjct: 912 CSEC------GKTFSEKSYVSAHQR----VHTGEKPYECNVCGKPFAHNSTLRVHQ---- 957
Query: 910 NIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFP 969
I GE S++CN C +TF ++ L H + H G K Y C CG+ F
Sbjct: 958 RIHTGEK------------SYECNDCGKTFSQKSHLSAHQRIHTG-EKPYECNECGKAFA 1004
Query: 970 SLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMH 1010
TL H+ H+ K ++ + H +MH
Sbjct: 1005 QNSTLRVHQRIHTGEKPYECDECGKTFVRKAALRVHHTRMH 1045
Score = 169 bits (428), Expect = 2e-41
Identities = 186/797 (23%), Positives = 288/797 (36%), Gaps = 155/797 (19%)
Query: 32 PECDQKTSRALEDRNSVTSQEERNEDDEDMEDESIYTCDHCQQDFESLADLTDH-RAHRC 90
P +KT + E S S + +Y C+ C + F ++L+ H R H
Sbjct: 405 PHSGEKTYQYEECAKSFCSSSHPIQHPGTYVGFKLYECNECGKAFCQNSNLSKHLRIHTK 464
Query: 91 PGDGDDDPQLSWVASSPSSKDVASPTQMIGDGCDLGLGEEEGGTGLPYPCQFCDKSFIRL 150
D++ S K Q +L G E G T
Sbjct: 465 EKPCDNN------GCGRSYKSPLIGHQKTDAEMELCGGSEYGKT---------------- 502
Query: 151 SYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLK 210
S+LK H++I + P++C C + F H ++HTG+K Y C ECE FS HL
Sbjct: 503 SHLKGHQRILMGEKPYECIECGKTFSKTSHLRAHQRIHTGEKPYECVECEKTFSHKTHLS 562
Query: 211 IHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEKEAKKDDFMCDYCED 270
+H + H+ KP++C C + F+ S+L++H + H K + C CE
Sbjct: 563 VHQRVHTGEKPYECNDCGKSFTYNSALRAHQRIHTGEK-------------PYECSDCEK 609
Query: 271 TFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQAHANQK-HKCPMCP 329
TF+ L H H + + +C C F + L AH + H +K ++C C
Sbjct: 610 TFAHNSALRAH----HRIHTGEKPYECNECGRSFAHISVLKAH-QRIHTGEKPYECNECG 664
Query: 330 EQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDSSASVERGSTPDSTLK 389
F+ + H H + P + E+ +S LK
Sbjct: 665 RSFTYNSALRAHQRIH----------------------TGRKPYECSDCEKTFAHNSALK 702
Query: 390 PLR----GQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQI 445
+ G+K Y C C K F + L H + IH ++ + C
Sbjct: 703 IHQRIHTGEKP------------YECNECEK-TFAHNSALRAH-QNIHTG--EKLYECSE 746
Query: 446 CLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCG 505
C + L+ H R++H + C+ C + F+ + L H R+
Sbjct: 747 CGKTFFQKTRLSTH-RRIHTGE----------KPYECSKCGKTFSQKSYLSGHERI---- 791
Query: 506 PNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVYSC 565
G + CN C F+ +++L H Q+ H E P Y C
Sbjct: 792 -----HTGEKPYECNVCGKTFVYKAALIVH-QRIHTG------EKP-----------YEC 828
Query: 566 PYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASAN 625
C G H+ AH + E+ ++ + L A +
Sbjct: 829 NQC------GKTFSQRTHL--------CAHQRIHTGEKPYECNECGKTFADNSALRAH-H 873
Query: 626 SISNGE--YPCNQCDLKFSNFESFQTHLKLHLELLL--RKQACPQCKEDFDSQESLLQHL 681
I GE Y CN C FS +HL+ HL + C +C + F + + H
Sbjct: 874 RIHTGEKPYECNDCGKTFSK----TSHLRAHLRTRSGEKPYECSECGKTFSEKSYVSAHQ 929
Query: 682 TVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAV 741
VH T Y C C K F+ L+ H Y C C + F K + H +
Sbjct: 930 RVH--TGEKPYECNVCGKPFAHNSTLRVHQRIHTGEKSYECNDCGKTFSQKSHLSAHQRI 987
Query: 742 KHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHIT 801
H+ EK Y C C F + + L+VH + H G K ++C CG+TF + L+ H T
Sbjct: 988 -HTGEKP-YECNECGKAFAQNSTLRVH-QRIHTGE--KPYECDECGKTFVRKAALRVHHT 1042
Query: 802 ---THSKKYNCKFCSKA 815
T K C K+
Sbjct: 1043 RMHTREKTLACNGFGKS 1059
Score = 154 bits (388), Expect = 7e-37
Identities = 174/787 (22%), Positives = 278/787 (35%), Gaps = 150/787 (19%)
Query: 521 QCSMGFLTESSLTEH---------IQQAHCSVGSAKLESPVVQP-TQSFMEVYSCPYCTN 570
+C F ++ L +H Q C+ P+ P T ++Y C C
Sbjct: 388 KCRKSFYRKAHLIQHQRPHSGEKTYQYEECAKSFCSSSHPIQHPGTYVGFKLYECNECGK 447
Query: 571 SPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPV----SSDVEVSSPKRQRLSASAN- 625
+ F L+KH++ + K P ++ ++ +SP+ +D E+ +++
Sbjct: 448 A--FCQNSNLSKHLRIHTKEKPCDNNGCGRSYKSPLIGHQKTDAEMELCGGSEYGKTSHL 505
Query: 626 ----SISNGE--YPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQ 679
I GE Y C +C FS + H ++H + C +C++ F + L
Sbjct: 506 KGHQRILMGEKPYECIECGKTFSKTSHLRAHQRIHTGE--KPYECVECEKTFSHKTHLSV 563
Query: 680 HLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHL 739
H VH T Y C C K F+ L+ H Y C+ C++ F +++ H
Sbjct: 564 HQRVH--TGEKPYECNDCGKSFTYNSALRAHQRIHTGEKPYECSDCEKTFAHNSALRAHH 621
Query: 740 AVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCH 799
+ H+ EK Y C C F A + V H + K ++C CG +F+ L+ H
Sbjct: 622 RI-HTGEKP-YECNECGRSF---AHISVLKAHQRIHTGEKPYECNECGRSFTYNSALRAH 676
Query: 800 ITTHS--KKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPAD 857
H+ K Y C C K F L+ H R G P + E
Sbjct: 677 QRIHTGRKPYECSDCEKTFAHNSALKIHQR-------------IHTGEKPYECNECEKTF 723
Query: 858 LQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDD 917
A NS + ++ E +Y C CG + + L HR I GE
Sbjct: 724 ----------AHNSALRAHQNIHTGEKLYECSECGKTFFQKTRLSTHR----RIHTGEKP 769
Query: 918 GSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEH 977
++C+ C +TF ++ L H + H G K Y C +CG+ F L H
Sbjct: 770 ------------YECSKCGKTFSQKSYLSGHERIHTGE-KPYECNVCGKTFVYKAALIVH 816
Query: 978 KVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKI 1037
+ H+ C C H ++H + + C C +T L+
Sbjct: 817 QRIHTGEKPY-ECNQCGKTFSQRTHLCAHQRIHTGEKP----YECNECGKTFADNSALRA 871
Query: 1038 HGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLVKLDVNGLPYGLCAGCMA 1097
H H +K Y+C C K F L A
Sbjct: 872 HHRIHTG----------------EKPYECNDCGKTFSKTSHLR------------AHLRT 903
Query: 1098 RSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGPRKGT 1157
RS G P E C EC F + +H +V +
Sbjct: 904 RS------GEKPYE----------CSECGKTFSEKSYVSAHQRVHTGE------------ 935
Query: 1158 QTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHL 1217
K Y+C C F + +++H H E+ ++EC C + F + L H
Sbjct: 936 --------KPYECNVCGKPFAHNSTLRVHQRIHTGEK--SYECNDCGKTFSQKSHLSAHQ 985
Query: 1218 IEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNH 1277
H+ E ++C C F Q + L+ H +H E K Y+C +C + F + L+ H
Sbjct: 986 RIHTGEK---PYECNECGKAFAQNSTLRVHQ-RIHTGE-KPYECDECGKTFVRKAALRVH 1040
Query: 1278 TMSQHAQ 1284
H +
Sbjct: 1041 HTRMHTR 1047
Score = 114 bits (285), Expect = 6e-25
Identities = 145/665 (21%), Positives = 219/665 (32%), Gaps = 170/665 (25%)
Query: 635 NQCDLKFSNFESFQTHLKLHLE-LLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYV 693
N+C F H ++H E +C++ F + L+QH H + Y
Sbjct: 356 NECTDALYQKLDFTAHQRIHTEDKFYLSDEHGKCRKSFYRKAHLIQHQRPHSGEKTYQY- 414
Query: 694 CESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCT 753
E C K F S +H F LY C C + F ++ HL + H+ EK
Sbjct: 415 -EECAKSFCSSSHPIQHPGTYVGFKLYECNECGKAFCQNSNLSKHLRI-HTKEKPCDN-N 471
Query: 754 ACNWDFRK--------EADLQV----------HVK-HSHLGNPAKAHKCIFCGETFSTEV 794
C ++ +A++++ H+K H + K ++CI CG+TFS
Sbjct: 472 GCGRSYKSPLIGHQKTDAEMELCGGSEYGKTSHLKGHQRILMGEKPYECIECGKTFSKTS 531
Query: 795 ELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKK 852
L+ H I T K Y C C K F
Sbjct: 532 HLRAHQRIHTGEKPYECVECEKTF------------------------------------ 555
Query: 853 AEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIR 912
+ +H + V E Y C+ CG ++T L+ H+ I
Sbjct: 556 ---------------SHKTHLSVHQRVHTGEKPYECNDCGKSFTYNSALRAHQ----RIH 596
Query: 913 PGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLL 972
GE ++C+ C +TF + LR H + H G K Y C CG F +
Sbjct: 597 TGEKP------------YECSDCEKTFAHNSALRAHHRIHTGE-KPYECNECGRSFAHIS 643
Query: 973 TLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTST 1032
L H+ H+ C C H ++H + + C C +T
Sbjct: 644 VLKAHQRIHTGEKPY-ECNECGRSFTYNSALRAHQRIHTGRKP----YECSDCEKTFAHN 698
Query: 1033 LELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLVKLDVNGLPYGLC 1092
LKIH H +K Y+C C K F L
Sbjct: 699 SALKIHQRIHTG----------------EKPYECNECEKTFAHNSAL------------- 729
Query: 1093 AGCMARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSG 1152
N G C EC F L +H ++ +
Sbjct: 730 ----RAHQNIHTGEKL-----------YECSECGKTFFQKTRLSTHRRIHTGE------- 767
Query: 1153 PRKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAK 1212
K Y+C KC TF + + H H E+ +EC +C + F A
Sbjct: 768 -------------KPYECSKCGKTFSQKSYLSGHERIHTGEK--PYECNVCGKTFVYKAA 812
Query: 1213 LLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQT 1272
L+ H H+ E ++C C F Q L H +H E K Y+C++C + F +
Sbjct: 813 LIVHQRIHTGE---KPYECNQCGKTFSQRTHLCAH-QRIHTGE-KPYECNECGKTFADNS 867
Query: 1273 ELQNH 1277
L+ H
Sbjct: 868 ALRAH 872
>gi|150378520 zinc finger protein 594 [Homo sapiens]
Length = 807
Score = 174 bits (441), Expect = 5e-43
Identities = 179/765 (23%), Positives = 297/765 (38%), Gaps = 124/765 (16%)
Query: 119 IGDGCDLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHK 178
IG GC+ G G + + ++F + S L H++IH+ ++C C + F
Sbjct: 81 IGHGCNEGEKILSAGES-SHRYEVSGQNFKQKSGLTEHQKIHNINKTYECKECEKTFNRS 139
Query: 179 RSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQ 238
+ H ++HTG+K Y C+EC ++S +L IH + H+ KP+ C C + F+ +S+L
Sbjct: 140 SNLIIHQRIHTGNKPYVCNECGKDSNQSSNLIIHQRIHTGKKPYICHECGKDFNQSSNLV 199
Query: 239 SHMQAHKKNKEHLAKSEKEAKKDD---------------FMCDYCEDTFSQTEELEKHVL 283
H Q H + K +A K ++C+ C FSQ+ +L H
Sbjct: 200 RHKQIHSGGNPYECKECGKAFKGSSNLVLHQRIHSRGKPYLCNKCGKAFSQSTDLIIH-- 257
Query: 284 TRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQAHANQKH-KCPMCPEQFSSVEGVYCHL 342
H + + +C C ++F + L+ H + H +K KC C + F + HL
Sbjct: 258 --HRIHTGEKPYECYDCGQMFSQSSHLVPH-QRIHTGEKPLKCNECEKAFRQ----HSHL 310
Query: 343 DSHRQPDSSNHSVS----PDPVLGSVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMR 398
H++ S G A + + +E S + LR ++++
Sbjct: 311 TEHQRLHSGEKPYECHRCGKTFSGRTAFLKHQRLHAGEKIEECEKTFSKDEELREEQRIH 370
Query: 399 DDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNE 458
+ + Y C C R+F + L H T +KP + C +N +
Sbjct: 371 QE-----EKAYWCNQCG-RNFQGTSDLIRHQVTHTGEKPYECKEC-------GKTFNQSS 417
Query: 459 HVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFF 518
+ + H+ H+ C+ C + F + L H RV G +
Sbjct: 418 DLLRHHRIHS-------GEKPCVCSKCGKSFRGSSDLIRHHRV---------HTGEKPYE 461
Query: 519 CNQCSMGFLTESSLTEHIQQAH--------CSVGSA-KLESPVVQPTQ--SFMEVYSCPY 567
C++C F S L H Q+ H G A + S ++Q + S + Y C
Sbjct: 462 CSECGKAFSQRSHLVTH-QKIHTGEKPYQCTECGKAFRRRSLLIQHRRIHSGEKPYECKE 520
Query: 568 CTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSI 627
C I+ T +K H+++ H+ + + S D E+ ++ A A
Sbjct: 521 CGKLFIW-----RTAFLK--HQSL---HTGEKLECEKTFSQDEELRGEQKIHQEAKA--- 567
Query: 628 SNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMT 687
Y CNQC F H H + C +C + F+ LL+H +H +
Sbjct: 568 ----YWCNQCGRAFQGSSDLIRHQVTHTR--EKPYECKECGKTFNQSSDLLRHHRIH--S 619
Query: 688 TSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEK 747
YVC C K F DL KH Y C+ C + F + + H + H+ EK
Sbjct: 620 GEKPYVCNKCGKSFRGSSDLIKHHRIHTGEKPYECSECGKAFSQRSHLATHQKI-HTGEK 678
Query: 748 KMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCG-------------------- 787
Y+C+ C FR+ + L ++H L + K ++C CG
Sbjct: 679 P-YQCSECGNAFRRRSLL---IQHRRLHSGEKPYECKECGKLFMWHTAFLKHQRLHAGEK 734
Query: 788 -----ETFSTEVELQCHITTHSKK--YNCKFCSKAFHAIILLEKH 825
+TFS + EL+ TH +K Y C CS+ F L +H
Sbjct: 735 LEECEKTFSKDEELRKEQRTHQEKKVYWCNQCSRTFQGSSDLIRH 779
Score = 159 bits (401), Expect = 2e-38
Identities = 179/778 (23%), Positives = 277/778 (35%), Gaps = 158/778 (20%)
Query: 67 YTCDHCQQDFESLADL-------TDHRAHRCPGDGDDDPQLSWVASSPSSKDVASPTQMI 119
Y C C++ F ++L T ++ + C G D Q S + P
Sbjct: 127 YECKECEKTFNRSSNLIIHQRIHTGNKPYVCNECGKDSNQSSNLIIHQRIHTGKKPYICH 186
Query: 120 GDGCDLGLG------EEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSR 173
G D ++ G PY C+ C K+F S L H++IHS P+ C C +
Sbjct: 187 ECGKDFNQSSNLVRHKQIHSGGNPYECKECGKAFKGSSNLVLHQRIHSRGKPYLCNKCGK 246
Query: 174 LFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSS 233
F H ++HTG+K Y C++C FS+S HL H + H+ KP KC C++ F
Sbjct: 247 AFSQSTDLIIHHRIHTGEKPYECYDCGQMFSQSSHLVPHQRIHTGEKPLKCNECEKAFRQ 306
Query: 234 TSSLQSHMQAHKKNKEH------------LAKSEKEAKKDDFMCDYCEDTFSQTEELEKH 281
S L H + H K + A + + + CE TFS+ EEL +
Sbjct: 307 HSHLTEHQRLHSGEKPYECHRCGKTFSGRTAFLKHQRLHAGEKIEECEKTFSKDEELREE 366
Query: 282 VLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQAHANQKHKCPMCPEQFSSVEGVYCH 341
+ EKA C C F + L+ H + ++C C + F+ + H
Sbjct: 367 ---QRIHQEEKA-YWCNQCGRNFQGTSDLIRHQVTHTGEKPYECKECGKTFNQSSDLLRH 422
Query: 342 --LDSHRQPDSSNHSVSPDPVLGSVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRD 399
+ S +P V S + S+ + R + KP
Sbjct: 423 HRIHSGEKP--------------CVCSKCGKSFRGSSDLIRHHRVHTGEKP--------- 459
Query: 400 DGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEH 459
Y C C K F+ + L H K +KP Q C C + L +H
Sbjct: 460 ---------YECSECGKA-FSQRSHLVTHQKIHTGEKPYQ---CTECGKAFRRRSLLIQH 506
Query: 460 VRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNANPS-------- 511
R++H + C C ++F + +H + H G
Sbjct: 507 -RRIHSGE----------KPYECKECGKLFIWRTAFLKH-QSLHTGEKLECEKTFSQDEE 554
Query: 512 --------DGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVY 563
A++CNQC F S L H Q T + + Y
Sbjct: 555 LRGEQKIHQEAKAYWCNQCGRAFQGSSDLIRH------------------QVTHTREKPY 596
Query: 564 SCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSAS 623
C C + F L +H + + P +K K+ + SSD+
Sbjct: 597 ECKECGKT--FNQSSDLLRHHRIHSGEKPYVCNKCGKSFRG--SSDL-----------IK 641
Query: 624 ANSISNGE--YPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHL 681
+ I GE Y C++C FS TH K+H + C +C F + L+QH
Sbjct: 642 HHRIHTGEKPYECSECGKAFSQRSHLATHQKIHTG--EKPYQCSECGNAFRRRSLLIQHR 699
Query: 682 TVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTL--------CQEVFDSKV 733
+H + Y C+ C K F HT L H L C++ F
Sbjct: 700 RLH--SGEKPYECKECGKLFM-----------WHTAFLKHQRLHAGEKLEECEKTFSKDE 746
Query: 734 SIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFS 791
++ + EKK+Y C C+ F+ +DL ++H K ++C CG+T S
Sbjct: 747 ELRKE--QRTHQEKKVYWCNQCSRTFQGSSDL---IRHQVTHTREKPYECKECGKTQS 799
Score = 148 bits (373), Expect = 4e-35
Identities = 208/913 (22%), Positives = 315/913 (34%), Gaps = 206/913 (22%)
Query: 145 KSFIRLSYLKRHEQIHSDKLPFKCTY-C---------SRLFKHKRS-------------- 180
KS + +S K+ + S+KL + T C RL KH S
Sbjct: 5 KSKMEISEEKKSARAASEKLQRQITQECELVETSNSEDRLLKHWVSPLKDAMRHLPSQES 64
Query: 181 --RDRHI---KLHTGDKKYHCHECEAA----------------FSRSDHLKIHLKTHSSS 219
R+ HI K G+ + C+E E F + L H K H+ +
Sbjct: 65 GIREMHIIPQKAIVGEIGHGCNEGEKILSAGESSHRYEVSGQNFKQKSGLTEHQKIHNIN 124
Query: 220 KPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHL----AKSEKEAK-----------KDDFM 264
K ++C C++ F+ +S+L H + H NK ++ K ++ K ++
Sbjct: 125 KTYECKECEKTFNRSSNLIIHQRIHTGNKPYVCNECGKDSNQSSNLIIHQRIHTGKKPYI 184
Query: 265 CDYCEDTFSQTEELEKHVLTRHPQLSEKAD-LQCIHCPEVFVDENTLLAHIHQAHANQKH 323
C C F+Q+ L RH Q+ + +C C + F + L+ H + +
Sbjct: 185 CHECGKDFNQSSN-----LVRHKQIHSGGNPYECKECGKAFKGSSNLVLHQRIHSRGKPY 239
Query: 324 KCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDSSASVERGST 383
C C + FS + H HR D G + S SS +R T
Sbjct: 240 LCNKCGKAFSQSTDLIIH---HRIHTGEKPYECYD--CGQMFSQSS----HLVPHQRIHT 290
Query: 384 PDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTC 443
+ LK C C K F + L H + +KP + H C
Sbjct: 291 GEKPLK---------------------CNECEKA-FRQHSHLTEHQRLHSGEKPYECHRC 328
Query: 444 QICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSH 503
+H ++LH C + F+ L+E R+
Sbjct: 329 GKTFSGRTAFL---KH-QRLHAGE-------------KIEECEKTFSKDEELREEQRI-- 369
Query: 504 CGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVY 563
A++CNQC F S L H Q T + + Y
Sbjct: 370 -------HQEEKAYWCNQCGRNFQGTSDLIRH------------------QVTHTGEKPY 404
Query: 564 SCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSAS 623
C C + F L +H + + P SK K+ + SSD+
Sbjct: 405 ECKECGKT--FNQSSDLLRHHRIHSGEKPCVCSKCGKSFRG--SSDL-----------IR 449
Query: 624 ANSISNGE--YPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHL 681
+ + GE Y C++C FS TH K+H + C +C + F + L+QH
Sbjct: 450 HHRVHTGEKPYECSECGKAFSQRSHLVTHQKIHTG--EKPYQCTECGKAFRRRSLLIQHR 507
Query: 682 TVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAV 741
+H + Y C+ C K F KH +HT C++ F ++
Sbjct: 508 RIH--SGEKPYECKECGKLFIWRTAFLKH-QSLHTGEKLE---CEKTFSQDEELRGE--Q 559
Query: 742 KHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHIT 801
K E K Y C C F+ +DL ++H K ++C CG+TF+ +L H
Sbjct: 560 KIHQEAKAYWCNQCGRAFQGSSDL---IRHQVTHTREKPYECKECGKTFNQSSDLLRHHR 616
Query: 802 THS--KKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQ 859
HS K Y C C K+F L KH R G P + A Q
Sbjct: 617 IHSGEKPYVCNKCGKSFRGSSDLIKHHR-------------IHTGEKPYECSECGKAFSQ 663
Query: 860 GMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGS 919
SH A+ + E Y C CG A+ LL HR +P E
Sbjct: 664 ----------RSHLATHQKIHTGEKPYQCSECGNAFRRRSLLIQHRRLHSGEKPYECKEC 713
Query: 920 RK---------KAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPS 970
K K + + K C +TF + LR+ +TH+ K Y C C F
Sbjct: 714 GKLFMWHTAFLKHQRLHAGEKLEECEKTFSKDEELRKEQRTHQ-EKKVYWCNQCSRTFQG 772
Query: 971 LLTLTEHKVTHSK 983
L H+VTH++
Sbjct: 773 SSDLIRHQVTHTR 785
Score = 139 bits (351), Expect = 1e-32
Identities = 163/693 (23%), Positives = 263/693 (37%), Gaps = 75/693 (10%)
Query: 629 NGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTT 688
N Y C +C+ F+ + H ++H + C +C +D + +L+ H +H T
Sbjct: 124 NKTYECKECEKTFNRSSNLIIHQRIHTGN--KPYVCNECGKDSNQSSNLIIHQRIH--TG 179
Query: 689 STHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKK 748
Y+C C K F+ +L +H Y C C + F ++ +H + HS K
Sbjct: 180 KKPYICHECGKDFNQSSNLVRHKQIHSGGNPYECKECGKAFKGSSNLVLHQRI-HSRGKP 238
Query: 749 MYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCH--ITTHSKK 806
Y C C F + DL +H + H G K ++C CG+ FS L H I T K
Sbjct: 239 -YLCNKCGKAFSQSTDLIIHHR-IHTGE--KPYECYDCGQMFSQSSHLVPHQRIHTGEKP 294
Query: 807 YNCKFCSKAF--HAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLK 864
C C KAF H+ + + L ++ T +G + A + +
Sbjct: 295 LKCNECEKAFRQHSHLTEHQRLHSGEKPYECHRCGKTFSGRTAFLKHQRLHAGEKIEECE 354
Query: 865 NPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRK--- 921
+ + E + E Y C+ CG + L H++ +P E K
Sbjct: 355 KTFSKDEELREEQRIHQEEKAYWCNQCGRNFQGTSDLIRHQVTHTGEKPYECKECGKTFN 414
Query: 922 KAEFIKGSHK---------CNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLL 972
++ + H+ C+ C ++F + L H + H G K Y C CG+ F
Sbjct: 415 QSSDLLRHHRIHSGEKPCVCSKCGKSFRGSSDLIRHHRVHTGE-KPYECSECGKAFSQ-- 471
Query: 973 TLTEHKVTHSKSLDTGT----CRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQT 1028
H VTH K + TG C C + I+H ++H + + C C +
Sbjct: 472 --RSHLVTHQK-IHTGEKPYQCTECGKAFRRRSLLIQHRRIHSGEKP----YECKECGKL 524
Query: 1029 VTSTLELKIHGTFHM-QKLAGSSAASSPNG-QGLQKL------YKCALCLKEFRSKQDLV 1080
H + H +KL S +G QK+ Y C C + F+ DL+
Sbjct: 525 FIWRTAFLKHQSLHTGEKLECEKTFSQDEELRGEQKIHQEAKAYWCNQCGRAFQGSSDLI 584
Query: 1081 KLDVNGL---PYGLCAGCMARSANGQVGGLAPPE--PADRPCAGLRCPECSVKFESAEDL 1135
+ V PY C C ++ N L ++P C +C F + DL
Sbjct: 585 RHQVTHTREKPYE-CKEC-GKTFNQSSDLLRHHRIHSGEKPYV---CNKCGKSFRGSSDL 639
Query: 1136 ESHMQVDHRDLTPETSGPRKG--------TQTSPVPRKKTYQCIKCQMTFENEREIQIHV 1187
H ++ + E S K T +K YQC +C F + H
Sbjct: 640 IKHHRIHTGEKPYECSECGKAFSQRSHLATHQKIHTGEKPYQCSECGNAFRRRSLLIQHR 699
Query: 1188 ANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQH 1247
H E+ +ECK C ++F L H H+ E + +C F+ + K Q+
Sbjct: 700 RLHSGEKP--YECKECGKLFMWHTAFLKHQRLHAGEKLE---ECEKTFSKDEELRKEQR- 753
Query: 1248 IFAVHGQEDKIYDCSQCPQKFFFQTELQNHTMS 1280
H QE K+Y C+QC + F ++L H ++
Sbjct: 754 ---TH-QEKKVYWCNQCSRTFQGSSDLIRHQVT 782
Score = 132 bits (332), Expect = 2e-30
Identities = 182/808 (22%), Positives = 278/808 (34%), Gaps = 147/808 (18%)
Query: 438 QQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINSLQE 497
+ SH ++ + L EH +K+H + + C C + F ++L
Sbjct: 96 ESSHRYEVSGQNFKQKSGLTEH-QKIHNIN----------KTYECKECEKTFNRSSNLII 144
Query: 498 HIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPTQ 557
H R+ GN + CN+C S+L H Q+ H
Sbjct: 145 HQRIH---------TGNKPYVCNECGKDSNQSSNLIIH-QRIHTG--------------- 179
Query: 558 SFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKR 617
+ Y C C F L +H + + P + KA + SS++ +
Sbjct: 180 --KKPYICHECGKD--FNQSSNLVRHKQIHSGGNPYECKECGKAFKG--SSNLVL----H 229
Query: 618 QRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESL 677
QR+ + Y CN+C FS H ++H + C C + F L
Sbjct: 230 QRIHSRGKP-----YLCNKCGKAFSQSTDLIIHHRIHTGE--KPYECYDCGQMFSQSSHL 282
Query: 678 LQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQV 737
+ H +H T C C+K F L +H Y C C + F + +
Sbjct: 283 VPHQRIH--TGEKPLKCNECEKAFRQHSHLTEHQRLHSGEKPYECHRCGKTFSGRTAFLK 340
Query: 738 HLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQ 797
H + H+ EK C F K+ +L+ + + KA+ C CG F +L
Sbjct: 341 HQRL-HAGEK----IEECEKTFSKDEELR---EEQRIHQEEKAYWCNQCGRNFQGTSDLI 392
Query: 798 CHITTHS--KKYNCKFCSKAFHAIILLEKHLR----EKHCVF-----------DAATENG 840
H TH+ K Y CK C K F+ L +H R EK CV D +
Sbjct: 393 RHQVTHTGEKPYECKECGKTFNQSSDLLRHHRIHSGEKPCVCSKCGKSFRGSSDLIRHHR 452
Query: 841 TANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVL 900
G P + A Q SH + + E Y C CG A+ L
Sbjct: 453 VHTGEKPYECSECGKAFSQ----------RSHLVTHQKIHTGEKPYQCTECGKAFRRRSL 502
Query: 901 LQNHRLRDHNIRPGEDDGSRK---------KAEFIKGSHKCNVCSRTFFSENGLREHLQT 951
L HR +P E K K + + K C +TF + LR +
Sbjct: 503 LIQHRRIHSGEKPYECKECGKLFIWRTAFLKHQSLHTGEKLE-CEKTFSQDEELRGEQKI 561
Query: 952 HRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHP 1011
H+ AK Y C CG F L H+VTH++ C+ C + + H ++H
Sbjct: 562 HQ-EAKAYWCNQCGRAFQGSSDLIRHQVTHTRE-KPYECKECGKTFNQSSDLLRHHRIH- 618
Query: 1012 DLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLK 1071
+ + C C ++ + +L H H +K Y+C+ C K
Sbjct: 619 ---SGEKPYVCNKCGKSFRGSSDLIKHHRIHTG----------------EKPYECSECGK 659
Query: 1072 EFRSKQDLV---KLDVNGLPYGLCAGC----MARSANGQVGGLAPPEPADRPCAGLRCPE 1124
F + L K+ PY C+ C RS Q L ++P C E
Sbjct: 660 AFSQRSHLATHQKIHTGEKPY-QCSECGNAFRRRSLLIQHRRL---HSGEKP---YECKE 712
Query: 1125 CSVKFESAEDLESHMQVDHRDLTPETSGP-------RKGTQTSPVPRKKTYQCIKCQMTF 1177
C F H ++ + E RK +T KK Y C +C TF
Sbjct: 713 CGKLFMWHTAFLKHQRLHAGEKLEECEKTFSKDEELRKEQRTH--QEKKVYWCNQCSRTF 770
Query: 1178 ENEREIQIHVANHMIEEGINHECKLCNQ 1205
+ ++ H H E+ +ECK C +
Sbjct: 771 QGSSDLIRHQVTHTREK--PYECKECGK 796
Score = 129 bits (323), Expect = 2e-29
Identities = 124/523 (23%), Positives = 183/523 (34%), Gaps = 125/523 (23%)
Query: 43 EDRNSVTSQEERNEDDEDMEDESIYTCDHCQQDFESLADLTDHRAHRCPGDGDDDPQLSW 102
E + + EE E+ ++E Y C+ C ++F+ +DL H+
Sbjct: 352 ECEKTFSKDEELREEQRIHQEEKAYWCNQCGRNFQGTSDLIRHQVTH------------- 398
Query: 103 VASSPSSKDVASPTQMIGDGCDLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSD 162
GE+ PY C+ C K+F + S L RH +IHS
Sbjct: 399 ------------------------TGEK------PYECKECGKTFNQSSDLLRHHRIHSG 428
Query: 163 KLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPF 222
+ P C+ C + F+ RH ++HTG+K Y C EC AFS+ HL H K H+ KP+
Sbjct: 429 EKPCVCSKCGKSFRGSSDLIRHHRVHTGEKPYECSECGKAFSQRSHLVTHQKIHTGEKPY 488
Query: 223 KCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKS-----------EKEAKKDDFMCDYCEDT 271
+CT C + F S L H + H K + K K CE T
Sbjct: 489 QCTECGKAFRRRSLLIQHRRIHSGEKPYECKECGKLFIWRTAFLKHQSLHTGEKLECEKT 548
Query: 272 FSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQAHANQK-HKCPMCPE 330
FSQ EEL E C C F + L+ H H +K ++C C +
Sbjct: 549 FSQDEELRGEQKIH----QEAKAYWCNQCGRAFQGSSDLIRH-QVTHTREKPYECKECGK 603
Query: 331 QFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDSSASVERGSTPDSTLKP 390
F+ + H H S E+ + K
Sbjct: 604 TFNQSSDLLRHHRIH-------------------------------SGEKPYVCNKCGKS 632
Query: 391 LRGQKKMRDDGQGWT-KVVYSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQICLDS 449
RG + + T + Y C C K F+ + L H K +KP Q C C ++
Sbjct: 633 FRGSSDLIKHHRIHTGEKPYECSECGKA-FSQRSHLATHQKIHTGEKPYQ---CSECGNA 688
Query: 450 MPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNAN 509
L +H R+LH + C C ++F + +H R+ H G
Sbjct: 689 FRRRSLLIQH-RRLHSGE----------KPYECKECGKLFMWHTAFLKHQRL-HAGEKLE 736
Query: 510 PSD-----------------GNNAFFCNQCSMGFLTESSLTEH 535
+ ++CNQCS F S L H
Sbjct: 737 ECEKTFSKDEELRKEQRTHQEKKVYWCNQCSRTFQGSSDLIRH 779
Score = 91.7 bits (226), Expect = 4e-18
Identities = 56/190 (29%), Positives = 84/190 (44%), Gaps = 18/190 (9%)
Query: 64 ESIYTCDHCQQDFESLADLTDHRAHRCPGDGDDDPQLSWVASSPSSKDVASPTQMIGDGC 123
E Y C+ C + F +DL H HR G+ + S + S + + Q I G
Sbjct: 621 EKPYVCNKCGKSFRGSSDLIKH--HRI-HTGEKPYECSECGKAFSQRSHLATHQKIHTG- 676
Query: 124 DLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDR 183
PY C C +F R S L +H ++HS + P++C C +LF + +
Sbjct: 677 -----------EKPYQCSECGNAFRRRSLLIQHRRLHSGEKPYECKECGKLFMWHTAFLK 725
Query: 184 HIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQA 243
H +LH G+K ECE FS+ + L+ +TH K + C C R F +S L H
Sbjct: 726 HQRLHAGEK---LEECEKTFSKDEELRKEQRTHQEKKVYWCNQCSRTFQGSSDLIRHQVT 782
Query: 244 HKKNKEHLAK 253
H + K + K
Sbjct: 783 HTREKPYECK 792
Score = 78.6 bits (192), Expect = 4e-14
Identities = 81/365 (22%), Positives = 137/365 (37%), Gaps = 40/365 (10%)
Query: 921 KKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVT 980
+K I +++C C +TF + L H + H G K Y+C CG+ L H+
Sbjct: 118 QKIHNINKTYECKECEKTFNRSSNLIIHQRIHTG-NKPYVCNECGKDSNQSSNLIIHQRI 176
Query: 981 HSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGT 1040
H+ C C + H Q+H + + C C + + L +H
Sbjct: 177 HT-GKKPYICHECGKDFNQSSNLVRHKQIH----SGGNPYECKECGKAFKGSSNLVLHQR 231
Query: 1041 FHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLV---KLDVNGLPYGLCAGCMA 1097
H + K Y C C K F DL+ ++ PY C C
Sbjct: 232 IHSR----------------GKPYLCNKCGKAFSQSTDLIIHHRIHTGEKPYE-CYDC-- 272
Query: 1098 RSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPE--TSGPRK 1155
Q L P + L+C EC F L H ++ + E G
Sbjct: 273 GQMFSQSSHLVPHQRIHTGEKPLKCNECEKAFRQHSHLTEHQRLHSGEKPYECHRCGKTF 332
Query: 1156 GTQTSPVPRKKTY---QCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAK 1212
+T+ + ++ + + +C+ TF + E++ H E+ + C C + F +
Sbjct: 333 SGRTAFLKHQRLHAGEKIEECEKTFSKDEELREEQRIHQEEKA--YWCNQCGRNFQGTSD 390
Query: 1213 LLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQT 1272
L+ H + H+ E ++C C F Q++ L +H +H E K CS+C + F +
Sbjct: 391 LIRHQVTHTGE---KPYECKECGKTFNQSSDLLRH-HRIHSGE-KPCVCSKCGKSFRGSS 445
Query: 1273 ELQNH 1277
+L H
Sbjct: 446 DLIRH 450
Score = 65.1 bits (157), Expect = 4e-10
Identities = 79/357 (22%), Positives = 127/357 (35%), Gaps = 58/357 (16%)
Query: 927 KGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLD 986
+ SH+ V + F ++GL EH + H K Y C C + F L H+ H+ +
Sbjct: 96 ESSHRYEVSGQNFKQKSGLTEHQKIHN-INKTYECKECEKTFNRSSNLIIHQRIHTGNKP 154
Query: 987 TGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKL 1046
C C I H ++H + + C C + + L H H
Sbjct: 155 Y-VCNECGKDSNQSSNLIIHQRIHTGKKPYI----CHECGKDFNQSSNLVRHKQIH---- 205
Query: 1047 AGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLV---KLDVNGLPYGLCAGCMARSANGQ 1103
+ +P Y+C C K F+ +LV ++ G PY LC C A Q
Sbjct: 206 ----SGGNP--------YECKECGKAFKGSSNLVLHQRIHSRGKPY-LCNKC--GKAFSQ 250
Query: 1104 VGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGPRKGTQTSPVP 1163
L C +C F + L H ++ +
Sbjct: 251 STDLIIHHRIHTGEKPYECYDCGQMFSQSSHLVPHQRIHTGE------------------ 292
Query: 1164 RKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFE 1223
K +C +C+ F + H H E+ +EC C + F L H H+ E
Sbjct: 293 --KPLKCNECEKAFRQHSHLTEHQRLHSGEKP--YECHRCGKTFSGRTAFLKHQRLHAGE 348
Query: 1224 GMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNHTMS 1280
K C F + +L++ +H QE+K Y C+QC + F ++L H ++
Sbjct: 349 ------KIEECEKTFSKDEELREEQ-RIH-QEEKAYWCNQCGRNFQGTSDLIRHQVT 397
>gi|68303809 zinc finger protein 43 [Homo sapiens]
Length = 809
Score = 169 bits (429), Expect = 1e-41
Identities = 156/702 (22%), Positives = 274/702 (39%), Gaps = 91/702 (12%)
Query: 143 CDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAA 202
C K+F + S RH+ H++K FKC C + F +H +HT C +C A
Sbjct: 151 CVKAFHKFSNSNRHKISHTEKKLFKCKECGKSFCMLPHLAQHKIIHTRVNFCKCEKCGKA 210
Query: 203 FSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKK-------------NKE 249
F+ + H + ++ KP+ C C + F+ +S L +H + + + NK
Sbjct: 211 FNCPSIITKHKRINTGEKPYTCEECGKVFNWSSRLTTHKKNYTRYKLYKCEECGKAFNKS 270
Query: 250 HLAKSEKEAKKDD--FMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDE 307
+ + K + + + C C F+Q+ L +H HP EK +C C + F
Sbjct: 271 SILTTHKIIRTGEKFYKCKECAKAFNQSSNLTEHKKI-HP--GEK-PYKCEECGKAFNWP 326
Query: 308 NTLLAHIHQAHANQKHKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASM 367
+TL H + + C C + F+ + +L +H++ ++ + +
Sbjct: 327 STLTKHKRIHTGEKPYTCEECGKAFNQ----FSNLTTHKRIHTAEKFYKCTECGEAFSRS 382
Query: 368 SSATPDSSASVERGSTP-DSTLKPLRGQKKMRDDGQGWT-KVVYSCPYCSKRDFNSLAVL 425
S+ T E+ + K + K+ + T + Y C C K FN + L
Sbjct: 383 SNLTKHKKIHTEKKPYKCEECGKAFKWSSKLTEHKLTHTGEKPYKCEECGKA-FNWPSTL 441
Query: 426 EIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYC 485
H + +KP + C++C + NL H +++H + C C
Sbjct: 442 TKHNRIHTGEKP---YKCEVCGKAFNQFSNLTTH-KRIHTAE----------KPYKCEEC 487
Query: 486 PEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGS 545
+ F+ ++L +H ++ + C +C F S LTEH
Sbjct: 488 GKAFSRSSNLTKHKKI---------HIEKKPYKCEECGKAFKWSSKLTEH---------- 528
Query: 546 AKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSP 605
+ T + + Y C C + SIL K I K K+ + S
Sbjct: 529 --------KITHTGEKPYKCEECGKAFNHFSILTKHKRIHTGEKPYKCEECGKAFTQSSN 580
Query: 606 VSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACP 665
+++ ++ + ++ Y C +C F+ + TH K+H + C
Sbjct: 581 LTTHKKIHTGEK-------------FYKCEECGKAFTQSSNLTTHKKIHTG--GKPYKCE 625
Query: 666 QCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLC 725
+C + F+ +L +H +H T Y CE C K F L KH + Y C C
Sbjct: 626 ECGKAFNQFSTLTKHKIIH--TEEKPYKCEECGKAFKWSSTLTKHKIIHTGEKPYKCEEC 683
Query: 726 QEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIF 785
+ F ++ H + H+ EK Y+C C F + ++L ++H + + +KC
Sbjct: 684 GKAFKLSSTLSTHKII-HTGEKP-YKCEKCGKAFNRSSNL---IEHKKIHTGEQPYKCEE 738
Query: 786 CGETFSTEVELQCHITTHSKK--YNCKFCSKAFHAIILLEKH 825
CG+ F+ L H H+K+ Y CK C KAF+ L H
Sbjct: 739 CGKAFNYSSHLNTHKRIHTKEQPYKCKECGKAFNQYSNLTTH 780
Score = 166 bits (420), Expect = 1e-40
Identities = 141/615 (22%), Positives = 242/615 (39%), Gaps = 117/615 (19%)
Query: 138 YPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCH 197
Y C+ C K+F + S L H++IH + P+KC C + F + +H ++HTG+K Y C
Sbjct: 286 YKCKECAKAFNQSSNLTEHKKIHPGEKPYKCEECGKAFNWPSTLTKHKRIHTGEKPYTCE 345
Query: 198 ECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEKE 257
EC AF++ +L H + H++ K +KCT C FS +S+L H + H
Sbjct: 346 ECGKAFNQFSNLTTHKRIHTAEKFYKCTECGEAFSRSSNLTKHKKIH------------- 392
Query: 258 AKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQA 317
+K + C+ C F + +L +H LT + + +C C + F +TL H ++
Sbjct: 393 TEKKPYKCEECGKAFKWSSKLTEHKLTH----TGEKPYKCEECGKAFNWPSTLTKH-NRI 447
Query: 318 HANQK-HKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDSSA 376
H +K +KC +C + F+ + +L +H++ ++ + + + S+ T
Sbjct: 448 HTGEKPYKCEVCGKAFNQ----FSNLTTHKRIHTAEKPYKCEECGKAFSRSSNLTKHKKI 503
Query: 377 SVERGSTP-DSTLKPLRGQKKMRDDGQGWT-KVVYSCPYCSKRDFNSLAVLEIHLKTIHA 434
+E+ + K + K+ + T + Y C C K FN ++L H +
Sbjct: 504 HIEKKPYKCEECGKAFKWSSKLTEHKITHTGEKPYKCEECGKA-FNHFSILTKHKRIHTG 562
Query: 435 DKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINS 494
+KP + C+ C + NL H +K+H + + C C + F ++
Sbjct: 563 EKP---YKCEECGKAFTQSSNLTTH-KKIHTGEKF----------YKCEECGKAFTQSSN 608
Query: 495 LQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQ 554
L H ++ G + C +C F S+LT+H K+ +
Sbjct: 609 LTTHKKI---------HTGGKPYKCEECGKAFNQFSTLTKH-----------KIIHTEEK 648
Query: 555 PTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSS 614
P Y C C + + S LTKH
Sbjct: 649 P-------YKCEECGKAFKWSS--TLTKH------------------------------- 668
Query: 615 PKRQRLSASANSISNGE--YPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFD 672
I GE Y C +C F + TH +H + C +C + F+
Sbjct: 669 ----------KIIHTGEKPYKCEECGKAFKLSSTLSTHKIIHTG--EKPYKCEKCGKAFN 716
Query: 673 SQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSK 732
+L++H +H T Y CE C K F+ L H Y C C + F+
Sbjct: 717 RSSNLIEHKKIH--TGEQPYKCEECGKAFNYSSHLNTHKRIHTKEQPYKCKECGKAFNQY 774
Query: 733 VSIQVHLAVKHSNEK 747
++ H + H+ EK
Sbjct: 775 SNLTTHNKI-HTGEK 788
Score = 166 bits (419), Expect = 2e-40
Identities = 168/743 (22%), Positives = 272/743 (36%), Gaps = 128/743 (17%)
Query: 63 DESIYTCDHCQQDFESLADLTDHRAHRCPGDGDDDPQLSWVASSPSSKDVASPTQMIGDG 122
++ ++ C C + F L L H+ ++++ K P+ +I
Sbjct: 170 EKKLFKCKECGKSFCMLPHLAQHKIIHT--------RVNFCKCEKCGKAFNCPS-IITKH 220
Query: 123 CDLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRD 182
+ GE+ PY C+ C K F S L H++ ++ +KC C + F
Sbjct: 221 KRINTGEK------PYTCEECGKVFNWSSRLTTHKKNYTRYKLYKCEECGKAFNKSSILT 274
Query: 183 RHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQ 242
H + TG+K Y C EC AF++S +L H K H KP+KC C + F+ S+L H +
Sbjct: 275 THKIIRTGEKFYKCKECAKAFNQSSNLTEHKKIHPGEKPYKCEECGKAFNWPSTLTKHKR 334
Query: 243 AHKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPE 302
H K + C+ C F+Q L H + +EK +C C E
Sbjct: 335 IHTGEKP-------------YTCEECGKAFNQFSNLTTH---KRIHTAEKF-YKCTECGE 377
Query: 303 VFVDENTLLAHIHQAHANQK-HKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVL 361
F + L H + H +K +KC C + F + H +H P
Sbjct: 378 AFSRSSNLTKH-KKIHTEKKPYKCEECGKAFKWSSKLTEHKLTH---------TGEKPYK 427
Query: 362 GSVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNS 421
+ P + R T + KP Y C C K FN
Sbjct: 428 CEECGKAFNWPSTLTKHNRIHTGE---KP------------------YKCEVCGKA-FNQ 465
Query: 422 LAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFH 481
+ L H + A+KP + C+ C + NL +H +K+H +
Sbjct: 466 FSNLTTHKRIHTAEKP---YKCEECGKAFSRSSNLTKH-KKIHIEK----------KPYK 511
Query: 482 CNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHC 541
C C + F + L EH +++H G + C +C F S LT+H ++ H
Sbjct: 512 CEECGKAFKWSSKLTEH-KITHTG--------EKPYKCEECGKAFNHFSILTKH-KRIHT 561
Query: 542 SVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKA 601
E P Y C C + S L K I K K+
Sbjct: 562 G------EKP-----------YKCEECGKAFTQSSNLTTHKKIHTGEKFYKCEECGKAFT 604
Query: 602 EQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRK 661
+ S +++ ++ + + Y C +C F+ F + H +H E +
Sbjct: 605 QSSNLTTHKKIHTGGKP-------------YKCEECGKAFNQFSTLTKHKIIHTEE--KP 649
Query: 662 QACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYH 721
C +C + F +L +H +H T Y CE C K F L H + Y
Sbjct: 650 YKCEECGKAFKWSSTLTKHKIIH--TGEKPYKCEECGKAFKLSSTLSTHKIIHTGEKPYK 707
Query: 722 CTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAH 781
C C + F+ ++ H + H+ E+ Y+C C F + L H + + + +
Sbjct: 708 CEKCGKAFNRSSNLIEHKKI-HTGEQP-YKCEECGKAFNYSSHLNTHKR---IHTKEQPY 762
Query: 782 KCIFCGETFSTEVELQCHITTHS 804
KC CG+ F+ L H H+
Sbjct: 763 KCKECGKAFNQYSNLTTHNKIHT 785
Score = 160 bits (404), Expect = 1e-38
Identities = 172/741 (23%), Positives = 273/741 (36%), Gaps = 119/741 (16%)
Query: 583 HIKENHKNI-----------------PLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASAN 625
H+K++HK++ P SK ++ V + + S+ R ++S +
Sbjct: 113 HLKKDHKSVDECKVHRGGYNGFNQCLPATQSKIFLFDKC-VKAFHKFSNSNRHKISHTEK 171
Query: 626 SISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHY 685
+ + C +C F H +H + K C +C + F+ + +H ++
Sbjct: 172 KL----FKCKECGKSFCMLPHLAQHKIIHTRVNFCK--CEKCGKAFNCPSIITKHKRIN- 224
Query: 686 MTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSN 745
T Y CE C K F+ L H + + LY C C + F+ + H ++
Sbjct: 225 -TGEKPYTCEECGKVFNWSSRLTTHKKNYTRYKLYKCEECGKAFNKSSILTTHKIIR--T 281
Query: 746 EKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCH--ITTH 803
+K Y+C C F + ++L H K H G K +KC CG+ F+ L H I T
Sbjct: 282 GEKFYKCKECAKAFNQSSNLTEH-KKIHPGE--KPYKCEECGKAFNWPSTLTKHKRIHTG 338
Query: 804 SKKYNCKFCSKAFHAIILLEKHLR----EKHCVFDAATENGTANGVPPMAT--------K 851
K Y C+ C KAF+ L H R EK F TE G A T K
Sbjct: 339 EKPYTCEECGKAFNQFSNLTTHKRIHTAEK---FYKCTECGEAFSRSSNLTKHKKIHTEK 395
Query: 852 KAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNI 911
K + G K H+ + E Y C+ CG A+ L H
Sbjct: 396 KPYKCEECGKAFKWSSKLTEHKLTH----TGEKPYKCEECGKAFNWPSTLTKHNRIHTGE 451
Query: 912 RPGEDD------------GSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHY 959
+P + + + K+ + +KC C + F + L +H + H K Y
Sbjct: 452 KPYKCEVCGKAFNQFSNLTTHKRIHTAEKPYKCEECGKAFSRSSNLTKHKKIHI-EKKPY 510
Query: 960 MCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTG 1019
C CG+ F LTEHK+TH+ C C +H ++H +
Sbjct: 511 KCEECGKAFKWSSKLTEHKITHTGE-KPYKCEECGKAFNHFSILTKHKRIHTGEK----P 565
Query: 1020 FRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDL 1079
++C C + T + L H H +K YKC C K F +L
Sbjct: 566 YKCEECGKAFTQSSNLTTHKKIHTG----------------EKFYKCEECGKAFTQSSNL 609
Query: 1080 V---KLDVNGLPYGLCAGCMARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLE 1136
K+ G PY C C A Q L + +C EC F+ + L
Sbjct: 610 TTHKKIHTGGKPY-KCEEC--GKAFNQFSTLTKHKIIHTEEKPYKCEECGKAFKWSSTLT 666
Query: 1137 SHMQVDHRDLTPETSGPRKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEGI 1196
H ++ H +K Y+C +C F+ + H H E+
Sbjct: 667 KH-KIIHTG-------------------EKPYKCEECGKAFKLSSTLSTHKIIHTGEK-- 704
Query: 1197 NHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQED 1256
++C+ C + F+ + L+ H H+ E +KC C F ++ L H +H +E
Sbjct: 705 PYKCEKCGKAFNRSSNLIEHKKIHTGE---QPYKCEECGKAFNYSSHLNTH-KRIHTKEQ 760
Query: 1257 KIYDCSQCPQKFFFQTELQNH 1277
Y C +C + F + L H
Sbjct: 761 P-YKCKECGKAFNQYSNLTTH 780
Score = 149 bits (375), Expect = 2e-35
Identities = 177/797 (22%), Positives = 275/797 (34%), Gaps = 155/797 (19%)
Query: 189 TGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNK 248
T K + +C AF + + H +H+ K FKC C + F L H H +
Sbjct: 141 TQSKIFLFDKCVKAFHKFSNSNRHKISHTEKKLFKCKECGKSFCMLPHLAQHKIIH--TR 198
Query: 249 EHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSE-KADLQCIHCPEVFVDE 307
+ K EK K F C ++T+H +++ + C C +VF
Sbjct: 199 VNFCKCEKCGKA--FNCP--------------SIITKHKRINTGEKPYTCEECGKVFNWS 242
Query: 308 NTLLAHIHQAHANQKHKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASM 367
+ L H + +KC C + F+ + H +
Sbjct: 243 SRLTTHKKNYTRYKLYKCEECGKAFNKSSILTTH-----------KIIRTGEKFYKCKEC 291
Query: 368 SSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEI 427
+ A SS E + P G+K Y C C K FN + L
Sbjct: 292 AKAFNQSSNLTEH-----KKIHP--GEKP------------YKCEECGKA-FNWPSTLTK 331
Query: 428 HLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPE 487
H + +KP +TC+ C + NL H +++H + + C C E
Sbjct: 332 HKRIHTGEKP---YTCEECGKAFNQFSNLTTH-KRIHTAEKF----------YKCTECGE 377
Query: 488 MFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAK 547
F+ ++L +H ++ + C +C F S LTEH
Sbjct: 378 AFSRSSNLTKHKKIH---------TEKKPYKCEECGKAFKWSSKLTEH------------ 416
Query: 548 LESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVS 607
+ T + + Y C C + + S L I K K+ + S ++
Sbjct: 417 ------KLTHTGEKPYKCEECGKAFNWPSTLTKHNRIHTGEKPYKCEVCGKAFNQFSNLT 470
Query: 608 SDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQC 667
+ + + ++ Y C +C FS + H K+H+E + C +C
Sbjct: 471 THKRIHTAEKP-------------YKCEECGKAFSRSSNLTKHKKIHIEK--KPYKCEEC 515
Query: 668 KEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQE 727
+ F L +H H T Y CE C K F+ L KH Y C C +
Sbjct: 516 GKAFKWSSKLTEHKITH--TGEKPYKCEECGKAFNHFSILTKHKRIHTGEKPYKCEECGK 573
Query: 728 VFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCG 787
F ++ H + H+ EK Y+C C F + ++L H K H G K +KC CG
Sbjct: 574 AFTQSSNLTTHKKI-HTGEK-FYKCEECGKAFTQSSNLTTH-KKIHTGG--KPYKCEECG 628
Query: 788 ETFSTEVELQCH--ITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENGTANGV 845
+ F+ L H I T K Y C+ C KAF L KH G
Sbjct: 629 KAFNQFSTLTKHKIIHTEEKPYKCEECGKAFKWSSTLTKH-------------KIIHTGE 675
Query: 846 PPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHR 905
P ++ G K ++H+ + E Y C+ CG A+ L H+
Sbjct: 676 KPYKCEEC------GKAFKLSSTLSTHKI----IHTGEKPYKCEKCGKAFNRSSNLIEHK 725
Query: 906 LRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICG 965
I GE +KC C + F + L H + H + Y C CG
Sbjct: 726 ----KIHTGEQP------------YKCEECGKAFNYSSHLNTHKRIHT-KEQPYKCKECG 768
Query: 966 ERFPSLLTLTEHKVTHS 982
+ F LT H H+
Sbjct: 769 KAFNQYSNLTTHNKIHT 785
Score = 110 bits (276), Expect = 7e-24
Identities = 70/280 (25%), Positives = 120/280 (42%), Gaps = 40/280 (14%)
Query: 64 ESIYTCDHCQQDFESLADLTDHRAHRCPGDGDDDPQLSWVASSPSSKDVASPTQMIGDGC 123
E Y C+ C + F ++LT H+ G+ + + + + + I G
Sbjct: 563 EKPYKCEECGKAFTQSSNLTTHKKIHT---GEKFYKCEECGKAFTQSSNLTTHKKIHTG- 618
Query: 124 DLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDR 183
G PY C+ C K+F + S L +H+ IH+++ P+KC C + FK + +
Sbjct: 619 -----------GKPYKCEECGKAFNQFSTLTKHKIIHTEEKPYKCEECGKAFKWSSTLTK 667
Query: 184 HIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQA 243
H +HTG+K Y C EC AF S L H H+ KP+KC C + F+ +S+L H +
Sbjct: 668 HKIIHTGEKPYKCEECGKAFKLSSTLSTHKIIHTGEKPYKCEKCGKAFNRSSNLIEHKKI 727
Query: 244 HKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEV 303
H + + C+ C F+ + L H +++ +C C +
Sbjct: 728 H-------------TGEQPYKCEECGKAFNYSSHLNTHKRIH----TKEQPYKCKECGKA 770
Query: 304 FVDENTLLAHIHQAHANQKHKCP-------MCPEQFSSVE 336
F + L H ++ H +K P P+ FS+++
Sbjct: 771 FNQYSNLTTH-NKIHTGEKLYKPEDVTVILTTPQTFSNIK 809
Score = 77.4 bits (189), Expect = 8e-14
Identities = 105/505 (20%), Positives = 166/505 (32%), Gaps = 129/505 (25%)
Query: 782 KCIFCGETFSTEVELQCHITTHSKK--YNCKFCSKAFHAIILLEKH-LREKHCVFDAATE 838
KC+ FS H +H++K + CK C K+F + L +H + F +
Sbjct: 150 KCVKAFHKFSNSNR---HKISHTEKKLFKCKECGKSFCMLPHLAQHKIIHTRVNFCKCEK 206
Query: 839 NGTANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTME 898
G A P + TK ++ E Y C+ CG +
Sbjct: 207 CGKAFNCPSIITKHKR------------------------INTGEKPYTCEECGKVFNWS 242
Query: 899 VLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKH 958
L H+ + +R K +KC C + F + L H G K
Sbjct: 243 SRLTTHK----------KNYTRYKL------YKCEECGKAFNKSSILTTHKIIRTGE-KF 285
Query: 959 YMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLT 1018
Y C C + F LTEHK H C C +H ++H +
Sbjct: 286 YKCKECAKAFNQSSNLTEHKKIHPGEKPY-KCEECGKAFNWPSTLTKHKRIHTGEKP--- 341
Query: 1019 GFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQD 1078
+ C C + L H H +K YKC C + F +
Sbjct: 342 -YTCEECGKAFNQFSNLTTHKRIHTA----------------EKFYKCTECGEAFSRSSN 384
Query: 1079 LVK---LDVNGLPYGLCAGCMARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDL 1135
L K + PY +C EC F+ + L
Sbjct: 385 LTKHKKIHTEKKPY-------------------------------KCEECGKAFKWSSKL 413
Query: 1136 ESHMQVDHRDLTPETSGPRKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEG 1195
H K T T +K Y+C +C F + H H E+
Sbjct: 414 TEH----------------KLTHTG----EKPYKCEECGKAFNWPSTLTKHNRIHTGEKP 453
Query: 1196 INHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQE 1255
++C++C + F+ + L H H+ E +KC C F +++ L +H +H E
Sbjct: 454 --YKCEVCGKAFNQFSNLTTHKRIHTAEK---PYKCEECGKAFSRSSNLTKHK-KIH-IE 506
Query: 1256 DKIYDCSQCPQKFFFQTELQNHTMS 1280
K Y C +C + F + ++L H ++
Sbjct: 507 KKPYKCEECGKAFKWSSKLTEHKIT 531
>gi|54792150 zinc finger protein 473 [Homo sapiens]
Length = 871
Score = 165 bits (417), Expect = 3e-40
Identities = 191/811 (23%), Positives = 300/811 (36%), Gaps = 151/811 (18%)
Query: 39 SRALEDRNSVTSQEERNEDDEDMEDESIYTCDHCQQDFESLADLTDHRAHRCPGDGDDDP 98
+++ E R S + ++ D E E Y C C + F LT H
Sbjct: 181 AKSKEYRGEFFSYSDHSQQDSVQEGEKPYQCSECGKSFSGSYRLTQH------------- 227
Query: 99 QLSWVASSPSSKDVASPTQMIGDGCDLGLGEEEGGTGLP--------YPCQFCDKSFIRL 150
W+ + PT + C+ G + P Y C +F +
Sbjct: 228 ---WITHTRE-----KPT--VHQECEQGFDRNASLSVYPKTHTGYKFYVCNEYGTTFSQS 277
Query: 151 SYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLK 210
+YL H++ H+ + P K H H K HT K Y+C+EC AF+R HL
Sbjct: 278 TYL-WHQKTHTGEKPCKSQDSDHPPSHDTQPGEHQKTHTDSKSYNCNECGKAFTRIFHLT 336
Query: 211 IHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEKEAKKDDFMCDYCED 270
H K H + K ++C+ C+ +T +L+ H+ H+K H AK+ E C C
Sbjct: 337 RHQKIH-TRKRYECSKCQ----ATFNLRKHLIQHQKT--HAAKTTSE-------CQECGK 382
Query: 271 TFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQAHANQK-HKCPMCP 329
F + L +H + + +C + F +TL H + H+ +K +KC C
Sbjct: 383 IFRHSSLLIEHQALH----AGEEPYKCNERGKSFRHNSTLKIH-QRVHSGEKPYKCSECG 437
Query: 330 EQFSSVEGVYCHLDSHR------QPDSSNHSV----SPDPVLGSVASMSSATPDSSASVE 379
+ F + HL+ HR +P V P ++ A ++ P S A +
Sbjct: 438 KAFHR----HTHLNEHRRIHTGYRPHKCQECVRSFSRPSHLMRHQAIHTAEKPYSCAECK 493
Query: 380 RGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHADKPQQ 439
+ ++ L +KM K Y C C +R F + L+ H +++HA + Q
Sbjct: 494 ETFSDNNRLVQ---HQKMHT-----VKTPYECQECGER-FICGSTLKCH-ESVHAREKQG 543
Query: 440 SHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINSLQEHI 499
LD P E K F CN C + F+ L +H
Sbjct: 544 FFVSGKILDQNP------EQKEK----------------CFKCNKCEKTFSCSKYLTQHE 581
Query: 500 RVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPTQSF 559
R+ + G F C+QC F + L H Q S
Sbjct: 582 RIH--------TRGVKPFECDQCGKAFGQSTRLIHH------------------QRIHSR 615
Query: 560 MEVYSCPYCTNSPIFGSILKLTK-HIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQ 618
+ +Y + S++KL H KE H K S +S K Q
Sbjct: 616 VRLYKWGEQGKAISSASLIKLQSFHTKE--------HPFKCNECGKTFSHSAHLS--KHQ 665
Query: 619 RLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLL 678
+ A N + C++CD F+ H + H + C +C + F L
Sbjct: 666 LIHAGEN-----PFKCSKCDRVFTQRNYLVQHERTHAR--KKPLVCNECGKTFRQSSCLS 718
Query: 679 QHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVH 738
+H +H + YVC+ C K F +L +H Y C C + F + +H
Sbjct: 719 KHQRIH--SGEKPYVCDYCGKAFGLSAELVRHQRIHTGEKPYVCQECGKAFTQSSCLSIH 776
Query: 739 LAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQC 798
V H+ EK YRC C F ++A+L +H + K + C CG+ F L
Sbjct: 777 RRV-HTGEKP-YRCGECGKAFAQKANL---TQHQRIHTGEKPYSCNVCGKAFVLSAHLNQ 831
Query: 799 HITTHSKK--YNCKFCSKAFHAIILLEKHLR 827
H+ H+++ Y C+ C KAF L +H R
Sbjct: 832 HLRVHTQETLYQCQRCQKAFRCHSSLSRHQR 862
Score = 131 bits (329), Expect = 5e-30
Identities = 173/749 (23%), Positives = 260/749 (34%), Gaps = 117/749 (15%)
Query: 563 YSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSA 622
Y C C S F +LT+H + + P H + + S V + +
Sbjct: 209 YQCSECGKS--FSGSYRLTQHWITHTREKPTVHQECEQGFDRNASLSVYPKTHTGYKF-- 264
Query: 623 SANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLT 682
Y CN+ FS ++ H K H K D+Q +H
Sbjct: 265 ---------YVCNEYGTTFSQ-STYLWHQKTHTGEKPCKSQDSDHPPSHDTQPG--EHQK 312
Query: 683 VHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVK 742
H T S Y C C K F+ + L +H +HT Y C+ CQ F+ + + H K
Sbjct: 313 TH--TDSKSYNCNECGKAFTRIFHLTRHQ-KIHTRKRYECSKCQATFNLRKHLIQHQ--K 367
Query: 743 HSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHITT 802
K C C FR + L ++H L + +KC G++F L+ H
Sbjct: 368 THAAKTTSECQECGKIFRHSSLL---IEHQALHAGEEPYKCNERGKSFRHNSTLKIHQRV 424
Query: 803 HS--KKYNCKFCSKAFHAIILLEKH------LREKHCVFDAATENGTANGVPPMATKKAE 854
HS K Y C C KAFH L +H R C + + ++ + A AE
Sbjct: 425 HSGEKPYKCSECGKAFHRHTHLNEHRRIHTGYRPHKCQECVRSFSRPSHLMRHQAIHTAE 484
Query: 855 PADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPG 914
K + N+ + + Y C CG + L+ H + G
Sbjct: 485 KP-YSCAECKETFSDNNRLVQHQKMHTVKTPYECQECGERFICGSTLKCHESVHAREKQG 543
Query: 915 EDDGSR---KKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSL 971
+ + E + KCN C +TF L +H + H K + C CG+ F
Sbjct: 544 FFVSGKILDQNPEQKEKCFKCNKCEKTFSCSKYLTQHERIHTRGVKPFECDQCGKAFGQS 603
Query: 972 LTLTEHKVTHSKSLDTGTCRICKMPLQ----SEEEFIE----HCQMHPDLRNSLTGFRCV 1023
L H+ HS+ R+ K Q S I+ H + HP F+C
Sbjct: 604 TRLIHHQRIHSR------VRLYKWGEQGKAISSASLIKLQSFHTKEHP--------FKCN 649
Query: 1024 VCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLVKLD 1083
C +T + + L H H A +P +KC+ C + F + LV+ +
Sbjct: 650 ECGKTFSHSAHLSKHQLIH--------AGENP--------FKCSKCDRVFTQRNYLVQHE 693
Query: 1084 VNGLPYGLCAGCMARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVD- 1142
A +P L C EC F + L H ++
Sbjct: 694 RTH---------------------ARKKP-------LVCNECGKTFRQSSCLSKHQRIHS 725
Query: 1143 -HRDLTPETSGPRKGTQTSPVPRK------KTYQCIKCQMTFENEREIQIHVANHMIEEG 1195
+ + G G V + K Y C +C F + IH H E+
Sbjct: 726 GEKPYVCDYCGKAFGLSAELVRHQRIHTGEKPYVCQECGKAFTQSSCLSIHRRVHTGEKP 785
Query: 1196 INHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQE 1255
+ C C + F A L H H+ E + C VC FV + L QH+ VH QE
Sbjct: 786 --YRCGECGKAFAQKANLTQHQRIHTGEK---PYSCNVCGKAFVLSAHLNQHL-RVHTQE 839
Query: 1256 DKIYDCSQCPQKFFFQTELQNHTMSQHAQ 1284
+Y C +C + F + L H + Q
Sbjct: 840 -TLYQCQRCQKAFRCHSSLSRHQRVHNKQ 867
Score = 109 bits (273), Expect = 1e-23
Identities = 176/842 (20%), Positives = 268/842 (31%), Gaps = 220/842 (26%)
Query: 249 EHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDEN 308
+H + + + + C C +FS + L +H +T H + +C E D N
Sbjct: 195 DHSQQDSVQEGEKPYQCSECGKSFSGSYRLTQHWIT-HTREKPTVHQEC----EQGFDRN 249
Query: 309 TLLAHIHQAHANQK-HKCPMCPEQFSSVEGVYCHLDSH--RQPDSSNHSVSPDPVLGSVA 365
L+ + H K + C FS ++ H +H +P S S P
Sbjct: 250 ASLSVYPKTHTGYKFYVCNEYGTTFSQSTYLW-HQKTHTGEKPCKSQDSDHP-------- 300
Query: 366 SMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVL 425
P +P QK D Y+C C K F + L
Sbjct: 301 ------------------PSHDTQPGEHQKTHTDSKS------YNCNECGKA-FTRIFHL 335
Query: 426 EIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYC 485
H K IH K + CQ +NL +H+ + K HA C C
Sbjct: 336 TRHQK-IHTRKRYECSKCQ-------ATFNLRKHLIQHQKTHAAKTTS-------ECQEC 380
Query: 486 PEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGS 545
++F + L EH + H G + CN+ F S+L H Q+ H
Sbjct: 381 GKIFRHSSLLIEH-QALHAG--------EEPYKCNERGKSFRHNSTLKIH-QRVHSG--- 427
Query: 546 AKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSP 605
E P Y C C G H+ E H+ I +
Sbjct: 428 ---EKP-----------YKCSEC------GKAFHRHTHLNE-HRRIHTGYRP-------- 458
Query: 606 VSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACP 665
+ C +C FS H +H + +C
Sbjct: 459 --------------------------HKCQECVRSFSRPSHLMRHQAIHTAE--KPYSCA 490
Query: 666 QCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKH--------------- 710
+CKE F L+QH +H T T Y C+ C ++F L+ H
Sbjct: 491 ECKETFSDNNRLVQHQKMH--TVKTPYECQECGERFICGSTLKCHESVHAREKQGFFVSG 548
Query: 711 -LLDMHTFV---LYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQ 766
+LD + + C C++ F + H + H+ K + C C F + L
Sbjct: 549 KILDQNPEQKEKCFKCNKCEKTFSCSKYLTQHERI-HTRGVKPFECDQCGKAFGQSTRLI 607
Query: 767 VHVK-HSHL-----GNPAKA------------------HKCIFCGETFSTEVELQCHITT 802
H + HS + G KA KC CG+TFS L H
Sbjct: 608 HHQRIHSRVRLYKWGEQGKAISSASLIKLQSFHTKEHPFKCNECGKTFSHSAHLSKHQLI 667
Query: 803 HSKK--YNCKFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQG 860
H+ + + C C + F L +H R A KK + G
Sbjct: 668 HAGENPFKCSKCDRVFTQRNYLVQHERTH-------------------ARKKPLVCNECG 708
Query: 861 MLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSR 920
+ + H+ + + E Y CD CG A+ + L H+ I GE
Sbjct: 709 KTFRQSSCLSKHQR----IHSGEKPYVCDYCGKAFGLSAELVRHQ----RIHTGEK---- 756
Query: 921 KKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVT 980
+ C C + F + L H + H G K Y C CG+ F LT+H+
Sbjct: 757 --------PYVCQECGKAFTQSSCLSIHRRVHTG-EKPYRCGECGKAFAQKANLTQHQRI 807
Query: 981 HSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGT 1040
H+ +C +C +H ++H T ++C C + L H
Sbjct: 808 HTGE-KPYSCNVCGKAFVLSAHLNQHLRVH----TQETLYQCQRCQKAFRCHSSLSRHQR 862
Query: 1041 FH 1042
H
Sbjct: 863 VH 864
Score = 109 bits (272), Expect = 2e-23
Identities = 55/187 (29%), Positives = 91/187 (48%), Gaps = 18/187 (9%)
Query: 137 PYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 196
P C C K+F + S L +H++IHS + P+ C YC + F RH ++HTG+K Y C
Sbjct: 701 PLVCNECGKTFRQSSCLSKHQRIHSGEKPYVCDYCGKAFGLSAELVRHQRIHTGEKPYVC 760
Query: 197 HECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEK 256
EC AF++S L IH + H+ KP++C C + F+ ++L H + H K
Sbjct: 761 QECGKAFTQSSCLSIHRRVHTGEKPYRCGECGKAFAQKANLTQHQRIHTGEK-------- 812
Query: 257 EAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQ 316
+ C+ C F + L +H+ +++ QC C + F ++L H +
Sbjct: 813 -----PYSCNVCGKAFVLSAHLNQHLRVH----TQETLYQCQRCQKAFRCHSSLSRH-QR 862
Query: 317 AHANQKH 323
H Q++
Sbjct: 863 VHNKQQY 869
Score = 102 bits (255), Expect = 2e-21
Identities = 57/212 (26%), Positives = 92/212 (43%), Gaps = 19/212 (8%)
Query: 137 PYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHC 196
P+ C CD+ F + +YL +HE+ H+ K P C C + F+ +H ++H+G+K Y C
Sbjct: 673 PFKCSKCDRVFTQRNYLVQHERTHARKKPLVCNECGKTFRQSSCLSKHQRIHSGEKPYVC 732
Query: 197 HECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEK 256
C AF S L H + H+ KP+ C C + F+ +S L H + H K
Sbjct: 733 DYCGKAFGLSAELVRHQRIHTGEKPYVCQECGKAFTQSSCLSIHRRVHTGEK-------- 784
Query: 257 EAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQL-SEKADLQCIHCPEVFVDENTLLAHIH 315
+ C C F+Q K LT+H ++ + + C C + FV L H+
Sbjct: 785 -----PYRCGECGKAFAQ-----KANLTQHQRIHTGEKPYSCNVCGKAFVLSAHLNQHLR 834
Query: 316 QAHANQKHKCPMCPEQFSSVEGVYCHLDSHRQ 347
++C C + F + H H +
Sbjct: 835 VHTQETLYQCQRCQKAFRCHSSLSRHQRVHNK 866
Score = 75.1 bits (183), Expect = 4e-13
Identities = 102/465 (21%), Positives = 155/465 (33%), Gaps = 107/465 (23%)
Query: 871 SHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGE----DDGSRKKAEF- 925
S + +D V E Y C CG +++ L H + +P + G + A
Sbjct: 194 SDHSQQDSVQEGEKPYQCSECGKSFSGSYRLTQHWITHTREKPTVHQECEQGFDRNASLS 253
Query: 926 ----IKGSHKCNVCSR--TFFSENGLREHLQTHRG------------------PAKH--- 958
+K VC+ T FS++ H +TH G P +H
Sbjct: 254 VYPKTHTGYKFYVCNEYGTTFSQSTYLWHQKTHTGEKPCKSQDSDHPPSHDTQPGEHQKT 313
Query: 959 ------YMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPD 1012
Y C CG+ F + LT H+ H++ C C+ + I+H + H
Sbjct: 314 HTDSKSYNCNECGKAFTRIFHLTRHQKIHTRK--RYECSKCQATFNLRKHLIQHQKTHA- 370
Query: 1013 LRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKE 1072
+ T C C + + L H H A P YKC K
Sbjct: 371 ---AKTTSECQECGKIFRHSSLLIEHQALH--------AGEEP--------YKCNERGKS 411
Query: 1073 FRSKQDL---VKLDVNGLPYGLCAGC-MARSANGQVGGLAPPEPADRPCAGLRCPECSVK 1128
FR L ++ PY C+ C A + + RP +C EC
Sbjct: 412 FRHNSTLKIHQRVHSGEKPY-KCSECGKAFHRHTHLNEHRRIHTGYRP---HKCQECVRS 467
Query: 1129 FESAEDLESHMQVDHRDLTPETSGPRKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVA 1188
F L H + +K Y C +C+ TF + + H
Sbjct: 468 FSRPSHLMRHQAIH--------------------TAEKPYSCAECKETFSDNNRLVQHQK 507
Query: 1189 NHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGMG----------------GTFKCP 1232
H ++ +EC+ C + F + L CH H+ E G FKC
Sbjct: 508 MHTVK--TPYECQECGERFICGSTLKCHESVHAREKQGFFVSGKILDQNPEQKEKCFKCN 565
Query: 1233 VCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNH 1277
C F + L QH +H + K ++C QC + F T L +H
Sbjct: 566 KCEKTFSCSKYLTQH-ERIHTRGVKPFECDQCGKAFGQSTRLIHH 609
Score = 62.0 bits (149), Expect = 4e-09
Identities = 90/399 (22%), Positives = 141/399 (35%), Gaps = 46/399 (11%)
Query: 911 IRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPS 970
+ GED +E K FFS + + G K Y C CG+ F
Sbjct: 162 VSTGEDSMVHNVSEKTLTPAKSKEYRGEFFSYSDHSQQDSVQEGE-KPYQCSECGKSFSG 220
Query: 971 LLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQ--- 1027
LT+H +TH++ T + C+ + + H TG++ VC +
Sbjct: 221 SYRLTQHWITHTREKPT-VHQECEQGFDRNASLSVYPKTH-------TGYKFYVCNEYGT 272
Query: 1028 TVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQ-----------KLYKCALCLKEFRSK 1076
T + + L T +K S + P Q K Y C C K F
Sbjct: 273 TFSQSTYLWHQKTHTGEKPCKSQDSDHPPSHDTQPGEHQKTHTDSKSYNCNECGKAFTRI 332
Query: 1077 QDLVK-LDVNGLPYGLCAGCMARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDL 1135
L + ++ C+ C A + L + C EC F + L
Sbjct: 333 FHLTRHQKIHTRKRYECSKCQATFNLRK--HLIQHQKTHAAKTTSECQECGKIFRHSSLL 390
Query: 1136 ESHMQVDHRDLTPETSGPR----KGTQTSPVPRK-----KTYQCIKCQMTFENEREIQIH 1186
H Q H P R + T + ++ K Y+C +C F + H
Sbjct: 391 IEH-QALHAGEEPYKCNERGKSFRHNSTLKIHQRVHSGEKPYKCSECGKAFHRHTHLNEH 449
Query: 1187 VANHMIEEGIN-HECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQ 1245
I G H+C+ C + F P+ L+ H H+ E + C C F N+L
Sbjct: 450 ---RRIHTGYRPHKCQECVRSFSRPSHLMRHQAIHTAE---KPYSCAECKETFSDNNRLV 503
Query: 1246 QHIFAVHGQEDKIYDCSQCPQKFFFQTELQNHTMSQHAQ 1284
QH +H + Y+C +C ++F + L+ H S HA+
Sbjct: 504 QH-QKMHTVKTP-YECQECGERFICGSTLKCHE-SVHAR 539
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.131 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 56,105,401
Number of Sequences: 37866
Number of extensions: 2911665
Number of successful extensions: 107285
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1055
Number of HSP's successfully gapped in prelim test: 92
Number of HSP's that attempted gapping in prelim test: 10264
Number of HSP's gapped (non-prelim): 22500
length of query: 1284
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1170
effective length of database: 13,930,794
effective search space: 16299028980
effective search space used: 16299028980
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.