Guide to the Human Genome
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Search of human proteins with 45643131

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45643131 oxidored-nitro domain-containing protein isoform 2
[Homo sapiens]
         (223 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45643131 oxidored-nitro domain-containing protein isoform 2 [...   455   e-128
gi|45643133 oxidored-nitro domain-containing protein isoform 1 [...   332   2e-91
gi|4503165 cullin 3 [Homo sapiens]                                     29   2.8  
gi|119829191 vacuolar protein sorting 33B (yeast homolog)) [Homo...    29   2.8  
gi|206597522 ArfGAP with SH3 domain, ankyrin repeat and PH domai...    29   3.7  
gi|4502249 ArfGAP with SH3 domain, ankyrin repeat and PH domain ...    29   3.7  
gi|62243658 PI-3-kinase-related kinase SMG-1 [Homo sapiens]            28   4.8  
gi|62955803 nucleoporin 188kDa [Homo sapiens]                          28   4.8  
gi|21362112 limb region 1 protein [Homo sapiens]                       28   6.3  

>gi|45643131 oxidored-nitro domain-containing protein isoform 2
           [Homo sapiens]
          Length = 223

 Score =  455 bits (1171), Expect = e-128
 Identities = 223/223 (100%), Positives = 223/223 (100%)

Query: 1   MSVRTLPLLFLNLGGEMLYILDQRLRAQNIPGDKARKVLNDIISTMFNRKFMEELFKPQE 60
           MSVRTLPLLFLNLGGEMLYILDQRLRAQNIPGDKARKVLNDIISTMFNRKFMEELFKPQE
Sbjct: 1   MSVRTLPLLFLNLGGEMLYILDQRLRAQNIPGDKARKVLNDIISTMFNRKFMEELFKPQE 60

Query: 61  LYSKKALRTVYERLAHASIMKLNQASMDKLYDLMTMAFKYQVLLCPRPKDVLLVTFNHLD 120
           LYSKKALRTVYERLAHASIMKLNQASMDKLYDLMTMAFKYQVLLCPRPKDVLLVTFNHLD
Sbjct: 61  LYSKKALRTVYERLAHASIMKLNQASMDKLYDLMTMAFKYQVLLCPRPKDVLLVTFNHLD 120

Query: 121 TIKGFIRDSPTILQQVDETLRQLTEIYGGLSAGEFQLIRQTLLIFFQDLHIRRECFWKHM 180
           TIKGFIRDSPTILQQVDETLRQLTEIYGGLSAGEFQLIRQTLLIFFQDLHIRRECFWKHM
Sbjct: 121 TIKGFIRDSPTILQQVDETLRQLTEIYGGLSAGEFQLIRQTLLIFFQDLHIRRECFWKHM 180

Query: 181 QETVHSAQCCLPGVGNYMEDRRRRLTFHYVYPFENFEFCTWAK 223
           QETVHSAQCCLPGVGNYMEDRRRRLTFHYVYPFENFEFCTWAK
Sbjct: 181 QETVHSAQCCLPGVGNYMEDRRRRLTFHYVYPFENFEFCTWAK 223


>gi|45643133 oxidored-nitro domain-containing protein isoform 1
           [Homo sapiens]
          Length = 389

 Score =  332 bits (851), Expect = 2e-91
 Identities = 174/188 (92%), Positives = 174/188 (92%), Gaps = 10/188 (5%)

Query: 1   MSVRTLPLLFLNLGGEMLYILDQRLRAQNIPGDKARK----------VLNDIISTMFNRK 50
           MSVRTLPLLFLNLGGEMLYILDQRLRAQNIPGDKARK          VLNDIISTMFNRK
Sbjct: 1   MSVRTLPLLFLNLGGEMLYILDQRLRAQNIPGDKARKDEWTEVDRKRVLNDIISTMFNRK 60

Query: 51  FMEELFKPQELYSKKALRTVYERLAHASIMKLNQASMDKLYDLMTMAFKYQVLLCPRPKD 110
           FMEELFKPQELYSKKALRTVYERLAHASIMKLNQASMDKLYDLMTMAFKYQVLLCPRPKD
Sbjct: 61  FMEELFKPQELYSKKALRTVYERLAHASIMKLNQASMDKLYDLMTMAFKYQVLLCPRPKD 120

Query: 111 VLLVTFNHLDTIKGFIRDSPTILQQVDETLRQLTEIYGGLSAGEFQLIRQTLLIFFQDLH 170
           VLLVTFNHLDTIKGFIRDSPTILQQVDETLRQLTEIYGGLSAGEFQLIRQTLLIFFQDLH
Sbjct: 121 VLLVTFNHLDTIKGFIRDSPTILQQVDETLRQLTEIYGGLSAGEFQLIRQTLLIFFQDLH 180

Query: 171 IRRECFWK 178
           IR   F K
Sbjct: 181 IRVSMFLK 188


>gi|4503165 cullin 3 [Homo sapiens]
          Length = 768

 Score = 29.3 bits (64), Expect = 2.8
 Identities = 31/163 (19%), Positives = 61/163 (37%), Gaps = 10/163 (6%)

Query: 22  DQRLRAQNIPGDKARKVLNDIISTMFNRKFMEELFKPQELYSKKALRTVYERLAHASIMK 81
           D ++R +  P     K +N I   + N          QE+  K      +E L   +   
Sbjct: 13  DTKMRIRAFPMTMDEKYVNSIWDLLKNAI--------QEIQRKNNSGLSFEELYRNAYTM 64

Query: 82  LNQASMDKLYDLMTMAFKYQVLLCPRPKDVLLVTFNHLDTIKGFIRDSPTILQQVDETLR 141
           +     +KLY  +       ++   R   +  +  N L T+     D  T +  + + L 
Sbjct: 65  VLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILM 124

Query: 142 QLTEIYGGLSAGEFQLIRQTLLIFFQDLHIRRECFWKHMQETV 184
            +  +Y  +     + +    LI F+D  +R  C   H+++T+
Sbjct: 125 YMDRVY--VQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTL 165


>gi|119829191 vacuolar protein sorting 33B (yeast homolog)) [Homo
           sapiens]
          Length = 617

 Score = 29.3 bits (64), Expect = 2.8
 Identities = 36/145 (24%), Positives = 63/145 (43%), Gaps = 21/145 (14%)

Query: 52  MEELFKPQELYSKKALRTVYERLAHASIMKLNQASMDKLYDLMTM-AFKYQVLLC----P 106
           +E+L   ++L+ +  L +  +R+A+ SI+K  Q  +DKLY +    A      LC    P
Sbjct: 30  LEQLPGKKDLFIEADLMSPLDRIANVSILK--QHEVDKLYKVENKPALSSNEQLCFLVRP 87

Query: 107 RPKDV-LLVTFNHLDTIKGFIRDSPTILQ----QVDETLRQLTEIYGGLSAGEF------ 155
           R K++  + +  + D + G  R    I         E + +   IYG +S  E+      
Sbjct: 88  RIKNMRYIASLVNADKLAGRTRKYKVIFSPQKFYACEMVLEEEGIYGDVSCDEWAFSLLP 147

Query: 156 ---QLIRQTLLIFFQDLHIRRECFW 177
               L+   L  FF+D  +  +  W
Sbjct: 148 LDVDLLSMELPEFFRDYFLEGDQRW 172


>gi|206597522 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
           isoform b [Homo sapiens]
          Length = 961

 Score = 28.9 bits (63), Expect = 3.7
 Identities = 20/68 (29%), Positives = 32/68 (47%)

Query: 79  IMKLNQASMDKLYDLMTMAFKYQVLLCPRPKDVLLVTFNHLDTIKGFIRDSPTILQQVDE 138
           ++K+N+  + K  DL+    KY    C   +D L    +   +I+    D  TI Q  DE
Sbjct: 202 LLKVNEIKIKKGVDLLQNLIKYFHAQCNFFQDGLKAVESLKPSIETLSTDLHTIKQAQDE 261

Query: 139 TLRQLTEI 146
             RQL ++
Sbjct: 262 ERRQLIQL 269


>gi|4502249 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
           isoform a [Homo sapiens]
          Length = 1006

 Score = 28.9 bits (63), Expect = 3.7
 Identities = 20/68 (29%), Positives = 32/68 (47%)

Query: 79  IMKLNQASMDKLYDLMTMAFKYQVLLCPRPKDVLLVTFNHLDTIKGFIRDSPTILQQVDE 138
           ++K+N+  + K  DL+    KY    C   +D L    +   +I+    D  TI Q  DE
Sbjct: 202 LLKVNEIKIKKGVDLLQNLIKYFHAQCNFFQDGLKAVESLKPSIETLSTDLHTIKQAQDE 261

Query: 139 TLRQLTEI 146
             RQL ++
Sbjct: 262 ERRQLIQL 269


>gi|62243658 PI-3-kinase-related kinase SMG-1 [Homo sapiens]
          Length = 3661

 Score = 28.5 bits (62), Expect = 4.8
 Identities = 27/93 (29%), Positives = 42/93 (45%), Gaps = 18/93 (19%)

Query: 65  KALRTVYERLAHASIMKLNQASMDKLYDLMTMAFKYQVLLCPRPKDVLLV--------TF 116
           KAL TV E+ A +S+M+L   S+  + + +        LLC   K +LLV        + 
Sbjct: 258 KALETVGEKKAFSSVMQLVMTSLQSILENVDT----PELLCKCVKCILLVARCYPHIFST 313

Query: 117 NHLDTIKGFI------RDSPTILQQVDETLRQL 143
           N  DT+   +         P++ QQV   L+ L
Sbjct: 314 NFRDTVDILVGWHIDHTQKPSLTQQVSGWLQSL 346


>gi|62955803 nucleoporin 188kDa [Homo sapiens]
          Length = 1749

 Score = 28.5 bits (62), Expect = 4.8
 Identities = 24/86 (27%), Positives = 37/86 (43%)

Query: 76   HASIMKLNQASMDKLYDLMTMAFKYQVLLCPRPKDVLLVTFNHLDTIKGFIRDSPTILQQ 135
            HA IM L  + + +   L  +     +LL P   + L +       +   +R     L  
Sbjct: 1117 HADIMHLTDSVVRRQLFLDVLDGTKALLLVPASVNCLRLGSMKCTLLLILLRQWKRELGS 1176

Query: 136  VDETLRQLTEIYGGLSAGEFQLIRQT 161
            VDE L  LTEI  G+   + QL+ +T
Sbjct: 1177 VDEILGPLTEILEGVLQADQQLMEKT 1202


>gi|21362112 limb region 1 protein [Homo sapiens]
          Length = 490

 Score = 28.1 bits (61), Expect = 6.3
 Identities = 20/73 (27%), Positives = 35/73 (47%), Gaps = 5/73 (6%)

Query: 77  ASIMKLNQASMDKLYDLMTMAFKYQVLLCPRPKDVLL-----VTFNHLDTIKGFIRDSPT 131
           ++++  + ASM+ LYDL      Y          +LL     V  + + T+ G +   PT
Sbjct: 169 SALIDNDAASMESLYDLWEFYLPYLYSCISLMGCLLLLLCTPVGLSRMFTVMGQLLVKPT 228

Query: 132 ILQQVDETLRQLT 144
           IL+ +DE +  +T
Sbjct: 229 ILEDLDEQIYIIT 241


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.141    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,745,217
Number of Sequences: 37866
Number of extensions: 298959
Number of successful extensions: 874
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 868
Number of HSP's gapped (non-prelim): 10
length of query: 223
length of database: 18,247,518
effective HSP length: 98
effective length of query: 125
effective length of database: 14,536,650
effective search space: 1817081250
effective search space used: 1817081250
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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