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Search of human proteins with 13236516
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13236516 Der1-like domain family, member 1 isoform a [Homo
sapiens]
(251 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13236516 Der1-like domain family, member 1 isoform a [Homo sa... 532 e-151
gi|197927278 Der1-like domain family, member 1 isoform b [Homo s... 480 e-136
gi|31455614 Der1-like domain family, member 2 [Homo sapiens] 145 2e-35
gi|209364542 derlin 3 isoform 1 [Homo sapiens] 144 7e-35
gi|50845411 derlin 3 isoform 2 [Homo sapiens] 144 7e-35
gi|50845409 derlin 3 isoform 3 [Homo sapiens] 144 7e-35
gi|4504059 gonadotropin-releasing hormone receptor isoform 1 [Ho... 32 0.52
gi|34577052 coagulation factor II (thrombin) receptor-like 1 pre... 30 2.6
gi|94818879 rhomboid domain containing 2 isoform b [Homo sapiens] 29 4.4
gi|94818790 rhomboid domain containing 2 isoform a [Homo sapiens] 29 4.4
gi|239753508 PREDICTED: hypothetical protein [Homo sapiens] 28 9.9
gi|239748157 PREDICTED: hypothetical protein [Homo sapiens] 28 9.9
gi|239742055 PREDICTED: hypothetical protein XP_002342401 [Homo ... 28 9.9
>gi|13236516 Der1-like domain family, member 1 isoform a [Homo
sapiens]
Length = 251
Score = 532 bits (1370), Expect = e-151
Identities = 251/251 (100%), Positives = 251/251 (100%)
Query: 1 MSDIGDWFRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITATF 60
MSDIGDWFRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITATF
Sbjct: 1 MSDIGDWFRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITATF 60
Query: 61 YFPVGPGTGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDMQL 120
YFPVGPGTGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDMQL
Sbjct: 61 YFPVGPGTGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDMQL 120
Query: 121 LMIPLIMSVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSVINELIGNLVG 180
LMIPLIMSVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSVINELIGNLVG
Sbjct: 121 LMIPLIMSVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSVINELIGNLVG 180
Query: 181 HLYFFLMFRYPMDLGGRNFLSTPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGGRH 240
HLYFFLMFRYPMDLGGRNFLSTPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGGRH
Sbjct: 181 HLYFFLMFRYPMDLGGRNFLSTPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGGRH 240
Query: 241 NWGQGFRLGDQ 251
NWGQGFRLGDQ
Sbjct: 241 NWGQGFRLGDQ 251
>gi|197927278 Der1-like domain family, member 1 isoform b [Homo
sapiens]
Length = 231
Score = 480 bits (1235), Expect = e-136
Identities = 231/251 (92%), Positives = 231/251 (92%), Gaps = 20/251 (7%)
Query: 1 MSDIGDWFRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITATF 60
MSDIGDWFRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITATF
Sbjct: 1 MSDIGDWFRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITATF 60
Query: 61 YFPVGPGTGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDMQL 120
YFPVGPGTGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDMQL
Sbjct: 61 YFPVGPGTGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDMQL 120
Query: 121 LMIPLIMSVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSVINELIGNLVG 180
LMIPLIMSVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGS
Sbjct: 121 LMIPLIMSVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGS----------- 169
Query: 181 HLYFFLMFRYPMDLGGRNFLSTPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGGRH 240
YPMDLGGRNFLSTPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGGRH
Sbjct: 170 ---------YPMDLGGRNFLSTPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGGRH 220
Query: 241 NWGQGFRLGDQ 251
NWGQGFRLGDQ
Sbjct: 221 NWGQGFRLGDQ 231
>gi|31455614 Der1-like domain family, member 2 [Homo sapiens]
Length = 239
Score = 145 bits (367), Expect = 2e-35
Identities = 90/254 (35%), Positives = 130/254 (51%), Gaps = 37/254 (14%)
Query: 8 FRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITATFYFPVGPG 67
+ IP ++R + A V +L LI+P L+ PE FQIWR IT +F GP
Sbjct: 10 YLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITNFLFF--GP- 66
Query: 68 TGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDMQLLMIPLIM 127
GF +L N+ FLY+Y LE G+F GR AD++FM LF + + GL + + L +
Sbjct: 67 VGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFLGQAFTI 126
Query: 128 SVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSVINELIGNLVGHLYFFLM 187
++YVW++ N + ++F+ F+A +LPWV++GF+ ++G S+I +L+G VGH+YFFL
Sbjct: 127 MLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGHIYFFLE 186
Query: 188 FRYPMDLGGRNFLSTPQFL------------YRWLPSRRGGVSGFGVPPASMRRAADQNG 235
+P GG L TP L Y LP R G GF
Sbjct: 187 DVFPNQPGGIRILKTPSILKAIFDTPDEDPNYNPLPEERPG--GFA-------------- 230
Query: 236 GGGRHNWGQGFRLG 249
WG+G RLG
Sbjct: 231 ------WGEGQRLG 238
>gi|209364542 derlin 3 isoform 1 [Homo sapiens]
Length = 239
Score = 144 bits (363), Expect = 7e-35
Identities = 73/199 (36%), Positives = 119/199 (59%), Gaps = 3/199 (1%)
Query: 8 FRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITATFYFPVGPG 67
F +PA+TR + AA V +L L+SP L+ P +FQ+WR +T +F GP
Sbjct: 10 FLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTNFLFF--GP- 66
Query: 68 TGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDMQLLMIPLIM 127
GF + N+ F+++Y LE G+F GR AD++FM LF + + + GL + L L+
Sbjct: 67 LGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFLGQALMA 126
Query: 128 SVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSVINELIGNLVGHLYFFLM 187
++YVW++ + + V+F+ F+A +LPW ++GF+ ++G S++ +L+G VGH+Y+FL
Sbjct: 127 MLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGHIYYFLE 186
Query: 188 FRYPMDLGGRNFLSTPQFL 206
+P GG+ L TP FL
Sbjct: 187 DVFPNQPGGKRLLQTPGFL 205
>gi|50845411 derlin 3 isoform 2 [Homo sapiens]
Length = 235
Score = 144 bits (363), Expect = 7e-35
Identities = 73/199 (36%), Positives = 119/199 (59%), Gaps = 3/199 (1%)
Query: 8 FRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITATFYFPVGPG 67
F +PA+TR + AA V +L L+SP L+ P +FQ+WR +T +F GP
Sbjct: 10 FLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTNFLFF--GP- 66
Query: 68 TGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDMQLLMIPLIM 127
GF + N+ F+++Y LE G+F GR AD++FM LF + + + GL + L L+
Sbjct: 67 LGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFLGQALMA 126
Query: 128 SVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSVINELIGNLVGHLYFFLM 187
++YVW++ + + V+F+ F+A +LPW ++GF+ ++G S++ +L+G VGH+Y+FL
Sbjct: 127 MLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGHIYYFLE 186
Query: 188 FRYPMDLGGRNFLSTPQFL 206
+P GG+ L TP FL
Sbjct: 187 DVFPNQPGGKRLLQTPGFL 205
>gi|50845409 derlin 3 isoform 3 [Homo sapiens]
Length = 205
Score = 144 bits (363), Expect = 7e-35
Identities = 73/199 (36%), Positives = 119/199 (59%), Gaps = 3/199 (1%)
Query: 8 FRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITATFYFPVGPG 67
F +PA+TR + AA V +L L+SP L+ P +FQ+WR +T +F GP
Sbjct: 10 FLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTNFLFF--GP- 66
Query: 68 TGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDMQLLMIPLIM 127
GF + N+ F+++Y LE G+F GR AD++FM LF + + + GL + L L+
Sbjct: 67 LGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFLGQALMA 126
Query: 128 SVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSVINELIGNLVGHLYFFLM 187
++YVW++ + + V+F+ F+A +LPW ++GF+ ++G S++ +L+G VGH+Y+FL
Sbjct: 127 MLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGHIYYFLE 186
Query: 188 FRYPMDLGGRNFLSTPQFL 206
+P GG+ L TP FL
Sbjct: 187 DVFPNQPGGKRLLQTPGFL 205
>gi|4504059 gonadotropin-releasing hormone receptor isoform 1 [Homo
sapiens]
Length = 328
Score = 32.0 bits (71), Expect = 0.52
Identities = 15/46 (32%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Query: 146 FGTRFKACYLPWVILGFNYIIGGSVINELIGNLVGHLYFFLMFRYP 191
F T F C+ P+ +LG Y ++N L + V H +F F P
Sbjct: 272 FATSFTVCWTPYYVLGIWYWFDPEMLNRL-SDPVNHFFFLFAFLNP 316
>gi|34577052 coagulation factor II (thrombin) receptor-like 1
precursor [Homo sapiens]
Length = 397
Score = 29.6 bits (65), Expect = 2.6
Identities = 17/61 (27%), Positives = 32/61 (52%), Gaps = 5/61 (8%)
Query: 128 SVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSVINELIGNLVGHLYFFLM 187
+V+Y+ D++ WF + + + I G N+I G ++ N LIG G++Y ++
Sbjct: 110 AVIYMANLALADLLSVIWFPLK-----IAYHIHGNNWIYGEALCNVLIGFFYGNMYCSIL 164
Query: 188 F 188
F
Sbjct: 165 F 165
>gi|94818879 rhomboid domain containing 2 isoform b [Homo sapiens]
Length = 223
Score = 28.9 bits (63), Expect = 4.4
Identities = 28/107 (26%), Positives = 54/107 (50%), Gaps = 7/107 (6%)
Query: 126 IMSVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYII-GGSVINELIGNLVGHLYF 184
++ V V +++ R ++ FG + +PW++LG +++I S ++ + G +G L +
Sbjct: 1 MLGVTTVRSRMRRALV----FGMVVPSVLVPWLLLGASWLIPQTSFLSNVCGLSIG-LAY 55
Query: 185 FLMFRYPMDLGGRNFLSTPQFLYRWLPSRRGGVSGFGVPPASMRRAA 231
L + Y +DL R L Q + + RR V + ++ RRAA
Sbjct: 56 GLTYCYSIDLSERVALKLDQ-TFPFSLMRRISVFKYVSGSSAERRAA 101
>gi|94818790 rhomboid domain containing 2 isoform a [Homo sapiens]
Length = 364
Score = 28.9 bits (63), Expect = 4.4
Identities = 28/107 (26%), Positives = 54/107 (50%), Gaps = 7/107 (6%)
Query: 126 IMSVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYII-GGSVINELIGNLVGHLYF 184
++ V V +++ R ++ FG + +PW++LG +++I S ++ + G +G L +
Sbjct: 142 MLGVTTVRSRMRRALV----FGMVVPSVLVPWLLLGASWLIPQTSFLSNVCGLSIG-LAY 196
Query: 185 FLMFRYPMDLGGRNFLSTPQFLYRWLPSRRGGVSGFGVPPASMRRAA 231
L + Y +DL R L Q + + RR V + ++ RRAA
Sbjct: 197 GLTYCYSIDLSERVALKLDQ-TFPFSLMRRISVFKYVSGSSAERRAA 242
>gi|239753508 PREDICTED: hypothetical protein [Homo sapiens]
Length = 123
Score = 27.7 bits (60), Expect = 9.9
Identities = 17/42 (40%), Positives = 18/42 (42%), Gaps = 11/42 (26%)
Query: 209 WLPSRRGGVSGFGVPPASMRRAAD---QNGGGGRHNWGQGFR 247
W P RGG +G RR A NGGGGR W R
Sbjct: 11 WRPGPRGGRAG--------RREAGGPGHNGGGGRARWAAAAR 44
>gi|239748157 PREDICTED: hypothetical protein [Homo sapiens]
Length = 128
Score = 27.7 bits (60), Expect = 9.9
Identities = 17/42 (40%), Positives = 18/42 (42%), Gaps = 11/42 (26%)
Query: 209 WLPSRRGGVSGFGVPPASMRRAAD---QNGGGGRHNWGQGFR 247
W P RGG +G RR A NGGGGR W R
Sbjct: 11 WRPGPRGGRAG--------RREAGGPGHNGGGGRARWAAAAR 44
>gi|239742055 PREDICTED: hypothetical protein XP_002342401 [Homo
sapiens]
Length = 128
Score = 27.7 bits (60), Expect = 9.9
Identities = 17/42 (40%), Positives = 18/42 (42%), Gaps = 11/42 (26%)
Query: 209 WLPSRRGGVSGFGVPPASMRRAAD---QNGGGGRHNWGQGFR 247
W P RGG +G RR A NGGGGR W R
Sbjct: 11 WRPGPRGGRAG--------RREAGGPGHNGGGGRARWAAAAR 44
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.331 0.149 0.510
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,881,797
Number of Sequences: 37866
Number of extensions: 457029
Number of successful extensions: 1064
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1053
Number of HSP's gapped (non-prelim): 13
length of query: 251
length of database: 18,247,518
effective HSP length: 100
effective length of query: 151
effective length of database: 14,460,918
effective search space: 2183598618
effective search space used: 2183598618
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.