Guide to the Human Genome
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Search of human proteins with 108796661

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|108796661 spindlin family, member 4 [Homo sapiens]
         (249 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|108796661 spindlin family, member 4 [Homo sapiens]                 518   e-147
gi|112293285 spindlin [Homo sapiens]                                  367   e-102
gi|115527078 spindlin family, member 3 [Homo sapiens]                 357   7e-99
gi|56682949 spindlin-like protein 2 [Homo sapiens]                    341   3e-94
gi|56682947 spindlin-like protein 2 [Homo sapiens]                    341   3e-94
gi|56682945 spindlin-like protein 2 [Homo sapiens]                    341   3e-94
gi|117606320 spindlin family, member 2 [Homo sapiens]                 340   9e-94
gi|6631095 minichromosome maintenance complex component 3 [Homo ...    31   1.2  
gi|111955326 MLX interacting protein [Homo sapiens]                    30   2.6  
gi|52485941 integrin, alpha 9 precursor [Homo sapiens]                 28   5.7  
gi|5454016 retinitis pigmentosa RP1 protein [Homo sapiens]             28   9.7  

>gi|108796661 spindlin family, member 4 [Homo sapiens]
          Length = 249

 Score =  518 bits (1333), Expect = e-147
 Identities = 249/249 (100%), Positives = 249/249 (100%)

Query: 1   MSPPTVPPMGVDGVSAYLMKKRHTHRKQRRKPTFLTRRNIVGCRIQHGWKEGNEPVEQWK 60
           MSPPTVPPMGVDGVSAYLMKKRHTHRKQRRKPTFLTRRNIVGCRIQHGWKEGNEPVEQWK
Sbjct: 1   MSPPTVPPMGVDGVSAYLMKKRHTHRKQRRKPTFLTRRNIVGCRIQHGWKEGNEPVEQWK 60

Query: 61  GTVLEQVSVKPTLYIIKYDGKDSVYGLELHRDKRVLALEILPERVPTPRIDSRLADSLIG 120
           GTVLEQVSVKPTLYIIKYDGKDSVYGLELHRDKRVLALEILPERVPTPRIDSRLADSLIG
Sbjct: 61  GTVLEQVSVKPTLYIIKYDGKDSVYGLELHRDKRVLALEILPERVPTPRIDSRLADSLIG 120

Query: 121 KAVEHVFEGEHGTKDEWKGMVLARAPVMDTWFYITYEKDPVLYMYTLLDDYKDGDLRIIP 180
           KAVEHVFEGEHGTKDEWKGMVLARAPVMDTWFYITYEKDPVLYMYTLLDDYKDGDLRIIP
Sbjct: 121 KAVEHVFEGEHGTKDEWKGMVLARAPVMDTWFYITYEKDPVLYMYTLLDDYKDGDLRIIP 180

Query: 181 DSNYYFPTAEQEPGEVVDSLVGKQVEHAKDDGSKRTGIFIHQVVAKPSVYFIKFDDDIHI 240
           DSNYYFPTAEQEPGEVVDSLVGKQVEHAKDDGSKRTGIFIHQVVAKPSVYFIKFDDDIHI
Sbjct: 181 DSNYYFPTAEQEPGEVVDSLVGKQVEHAKDDGSKRTGIFIHQVVAKPSVYFIKFDDDIHI 240

Query: 241 YVYGLVKTP 249
           YVYGLVKTP
Sbjct: 241 YVYGLVKTP 249


>gi|112293285 spindlin [Homo sapiens]
          Length = 262

 Score =  367 bits (941), Expect = e-102
 Identities = 184/245 (75%), Positives = 208/245 (84%), Gaps = 7/245 (2%)

Query: 10  GVDGVSAYLMKKRHTHRKQRR-----KPTFLTRRNIVGCRIQHGWKEGNEPVEQWKGTVL 64
           G  GVSA +MKKR +H+K R      KP    RRNIVGCRIQHGWKEGN PV QWKGTVL
Sbjct: 18  GHAGVSANMMKKRTSHKKHRSSVGPSKPVSQPRRNIVGCRIQHGWKEGNGPVTQWKGTVL 77

Query: 65  EQVSVKPTLYIIKYDGKDSVYGLELHRDKRVLALEILPERVPTPRI-DSRLADSLIGKAV 123
           +QV V P+LY+IKYDG D VYGLEL++D+RV ALE+LP+RV T RI D+ LAD++IGKAV
Sbjct: 78  DQVPVNPSLYLIKYDGFDCVYGLELNKDERVSALEVLPDRVATSRISDAHLADTMIGKAV 137

Query: 124 EHVFEGEHGTKDEWKGMVLARAPVMDTWFYITYEKDPVLYMYTLLDDYKDGDLRIIPDSN 183
           EH+FE E G+KDEW+GMVLARAPVM+TWFYITYEKDPVLYMY LLDDYK+GDLRI+PDSN
Sbjct: 138 EHMFETEDGSKDEWRGMVLARAPVMNTWFYITYEKDPVLYMYQLLDDYKEGDLRIMPDSN 197

Query: 184 YYFPTAEQEPGEVVDSLVGKQVEHAKDDGSKRTGIFIHQVVAKPSVYFIKFDDDIHIYVY 243
              P AE+EPGEVVDSLVGKQVE+AK+DGSKRTG+ IHQV AKPSVYFIKFDDD HIYVY
Sbjct: 198 -DSPPAEREPGEVVDSLVGKQVEYAKEDGSKRTGMVIHQVEAKPSVYFIKFDDDFHIYVY 256

Query: 244 GLVKT 248
            LVKT
Sbjct: 257 DLVKT 261


>gi|115527078 spindlin family, member 3 [Homo sapiens]
          Length = 258

 Score =  357 bits (915), Expect = 7e-99
 Identities = 172/240 (71%), Positives = 203/240 (84%), Gaps = 2/240 (0%)

Query: 10  GVDGVSAYLMKKRHTHRKQRRKPTFLTRRNIVGCRIQHGWKEGNEPVEQWKGTVLEQVSV 69
           G   VS  ++K++  H+K R +PT   R NIVGCRIQHGWK+G+EP+ QWKGTVL+QV V
Sbjct: 19  GHGSVSVTMIKRKAAHKKHRSRPTSQPRGNIVGCRIQHGWKDGDEPLTQWKGTVLDQVPV 78

Query: 70  KPTLYIIKYDGKDSVYGLELHRDKRVLALEILPERVPTPRI-DSRLADSLIGKAVEHVFE 128
            P+LY+IKYDG D VYGLELHRD+RV +LE+LP RV + RI D+ LA+ ++GKAVEH+FE
Sbjct: 79  NPSLYLIKYDGFDCVYGLELHRDERVSSLEVLPNRVASSRISDTHLAEIMVGKAVEHIFE 138

Query: 129 GEHGTKDEWKGMVLARAPVMDTWFYITYEKDPVLYMYTLLDDYKDGDLRIIPDSNYYFPT 188
            E G+K+EW+GMVLA+APVM+TWFYITYEKDPVLYMY LLDDYKDGDLRI+ DSN   P 
Sbjct: 139 TEEGSKNEWRGMVLAQAPVMNTWFYITYEKDPVLYMYQLLDDYKDGDLRILQDSN-DSPL 197

Query: 189 AEQEPGEVVDSLVGKQVEHAKDDGSKRTGIFIHQVVAKPSVYFIKFDDDIHIYVYGLVKT 248
           AE+EPGEV+DSLVGKQVE+AKDDGSKRTG+ IHQV AKPSVYFIKFDDD HIYVY LVKT
Sbjct: 198 AEREPGEVIDSLVGKQVEYAKDDGSKRTGMVIHQVEAKPSVYFIKFDDDFHIYVYDLVKT 257


>gi|56682949 spindlin-like protein 2 [Homo sapiens]
          Length = 258

 Score =  341 bits (875), Expect = 3e-94
 Identities = 162/234 (69%), Positives = 198/234 (84%), Gaps = 2/234 (0%)

Query: 15  SAYLMKKRHTHRKQRRKPTFLTRRNIVGCRIQHGWKEGNEPVEQWKGTVLEQVSVKPTLY 74
           SA + KK+ + +KQR +P+   RRNIVGCRI HGWKEG+EP+ QWKGTVL+QV + P+LY
Sbjct: 24  SANMTKKKVSQKKQRGRPSSQPRRNIVGCRISHGWKEGDEPITQWKGTVLDQVPINPSLY 83

Query: 75  IIKYDGKDSVYGLELHRDKRVLALEILPERVPTPRI-DSRLADSLIGKAVEHVFEGEHGT 133
           ++KYDG D VYGLELHRD+RVL+L+IL +RV +  I D+ LA+++IGKAVEH+FEGEHG+
Sbjct: 84  LVKYDGIDCVYGLELHRDERVLSLKILSDRVASSHISDANLANTIIGKAVEHMFEGEHGS 143

Query: 134 KDEWKGMVLARAPVMDTWFYITYEKDPVLYMYTLLDDYKDGDLRIIPDSNYYFPTAEQEP 193
           KDEW+GMVLA+AP+M  WFYITYEKDPVLYMY LLDDYK+GDLRI+P+S+   PT E+EP
Sbjct: 144 KDEWRGMVLAQAPIMKAWFYITYEKDPVLYMYQLLDDYKEGDLRIMPESSESPPT-EREP 202

Query: 194 GEVVDSLVGKQVEHAKDDGSKRTGIFIHQVVAKPSVYFIKFDDDIHIYVYGLVK 247
           G VVD L+GK VE+ K+DGSKR G+ IHQV AKPSVYFIKFDDD HIYVY LVK
Sbjct: 203 GGVVDGLIGKHVEYTKEDGSKRIGMVIHQVEAKPSVYFIKFDDDFHIYVYDLVK 256


>gi|56682947 spindlin-like protein 2 [Homo sapiens]
          Length = 258

 Score =  341 bits (875), Expect = 3e-94
 Identities = 162/234 (69%), Positives = 198/234 (84%), Gaps = 2/234 (0%)

Query: 15  SAYLMKKRHTHRKQRRKPTFLTRRNIVGCRIQHGWKEGNEPVEQWKGTVLEQVSVKPTLY 74
           SA + KK+ + +KQR +P+   RRNIVGCRI HGWKEG+EP+ QWKGTVL+QV + P+LY
Sbjct: 24  SANMTKKKVSQKKQRGRPSSQPRRNIVGCRISHGWKEGDEPITQWKGTVLDQVPINPSLY 83

Query: 75  IIKYDGKDSVYGLELHRDKRVLALEILPERVPTPRI-DSRLADSLIGKAVEHVFEGEHGT 133
           ++KYDG D VYGLELHRD+RVL+L+IL +RV +  I D+ LA+++IGKAVEH+FEGEHG+
Sbjct: 84  LVKYDGIDCVYGLELHRDERVLSLKILSDRVASSHISDANLANTIIGKAVEHMFEGEHGS 143

Query: 134 KDEWKGMVLARAPVMDTWFYITYEKDPVLYMYTLLDDYKDGDLRIIPDSNYYFPTAEQEP 193
           KDEW+GMVLA+AP+M  WFYITYEKDPVLYMY LLDDYK+GDLRI+P+S+   PT E+EP
Sbjct: 144 KDEWRGMVLAQAPIMKAWFYITYEKDPVLYMYQLLDDYKEGDLRIMPESSESPPT-EREP 202

Query: 194 GEVVDSLVGKQVEHAKDDGSKRTGIFIHQVVAKPSVYFIKFDDDIHIYVYGLVK 247
           G VVD L+GK VE+ K+DGSKR G+ IHQV AKPSVYFIKFDDD HIYVY LVK
Sbjct: 203 GGVVDGLIGKHVEYTKEDGSKRIGMVIHQVEAKPSVYFIKFDDDFHIYVYDLVK 256


>gi|56682945 spindlin-like protein 2 [Homo sapiens]
          Length = 258

 Score =  341 bits (875), Expect = 3e-94
 Identities = 162/234 (69%), Positives = 198/234 (84%), Gaps = 2/234 (0%)

Query: 15  SAYLMKKRHTHRKQRRKPTFLTRRNIVGCRIQHGWKEGNEPVEQWKGTVLEQVSVKPTLY 74
           SA + KK+ + +KQR +P+   RRNIVGCRI HGWKEG+EP+ QWKGTVL+QV + P+LY
Sbjct: 24  SANMTKKKVSQKKQRGRPSSQPRRNIVGCRISHGWKEGDEPITQWKGTVLDQVPINPSLY 83

Query: 75  IIKYDGKDSVYGLELHRDKRVLALEILPERVPTPRI-DSRLADSLIGKAVEHVFEGEHGT 133
           ++KYDG D VYGLELHRD+RVL+L+IL +RV +  I D+ LA+++IGKAVEH+FEGEHG+
Sbjct: 84  LVKYDGIDCVYGLELHRDERVLSLKILSDRVASSHISDANLANTIIGKAVEHMFEGEHGS 143

Query: 134 KDEWKGMVLARAPVMDTWFYITYEKDPVLYMYTLLDDYKDGDLRIIPDSNYYFPTAEQEP 193
           KDEW+GMVLA+AP+M  WFYITYEKDPVLYMY LLDDYK+GDLRI+P+S+   PT E+EP
Sbjct: 144 KDEWRGMVLAQAPIMKAWFYITYEKDPVLYMYQLLDDYKEGDLRIMPESSESPPT-EREP 202

Query: 194 GEVVDSLVGKQVEHAKDDGSKRTGIFIHQVVAKPSVYFIKFDDDIHIYVYGLVK 247
           G VVD L+GK VE+ K+DGSKR G+ IHQV AKPSVYFIKFDDD HIYVY LVK
Sbjct: 203 GGVVDGLIGKHVEYTKEDGSKRIGMVIHQVEAKPSVYFIKFDDDFHIYVYDLVK 256


>gi|117606320 spindlin family, member 2 [Homo sapiens]
          Length = 258

 Score =  340 bits (871), Expect = 9e-94
 Identities = 161/234 (68%), Positives = 197/234 (84%), Gaps = 2/234 (0%)

Query: 15  SAYLMKKRHTHRKQRRKPTFLTRRNIVGCRIQHGWKEGNEPVEQWKGTVLEQVSVKPTLY 74
           SA + KK+ + +KQR +P+   RRNIVGCRI HGWKEG+EP+ QWKGTVL+QV + P+LY
Sbjct: 24  SANMTKKKVSQKKQRGRPSSQPRRNIVGCRISHGWKEGDEPITQWKGTVLDQVPINPSLY 83

Query: 75  IIKYDGKDSVYGLELHRDKRVLALEILPERVPTPRI-DSRLADSLIGKAVEHVFEGEHGT 133
           ++KYDG D VYGLELHRD+RVL+L+IL +RV +  I D+ LA+++IGKAVEH+FEGEHG+
Sbjct: 84  LVKYDGIDCVYGLELHRDERVLSLKILSDRVASSHISDANLANTIIGKAVEHMFEGEHGS 143

Query: 134 KDEWKGMVLARAPVMDTWFYITYEKDPVLYMYTLLDDYKDGDLRIIPDSNYYFPTAEQEP 193
           KDEW+GMVLA+AP+M  WFYITYEKDPVLYMY LLDDYK+GDLRI+P+S+   PT E+EP
Sbjct: 144 KDEWRGMVLAQAPIMKAWFYITYEKDPVLYMYQLLDDYKEGDLRIMPESSESPPT-EREP 202

Query: 194 GEVVDSLVGKQVEHAKDDGSKRTGIFIHQVVAKPSVYFIKFDDDIHIYVYGLVK 247
           G VVD L+GK VE+ K+DGSKR G+ IHQV  KPSVYFIKFDDD HIYVY LVK
Sbjct: 203 GGVVDGLIGKHVEYTKEDGSKRIGMVIHQVETKPSVYFIKFDDDFHIYVYDLVK 256


>gi|6631095 minichromosome maintenance complex component 3 [Homo
           sapiens]
          Length = 808

 Score = 30.8 bits (68), Expect = 1.2
 Identities = 15/45 (33%), Positives = 28/45 (62%), Gaps = 4/45 (8%)

Query: 82  DSVYGLELHRDKRVLALEILPERVPT---PR-IDSRLADSLIGKA 122
           ++ YGL +++D + + ++ +PE+ P    PR +D  L D L+ KA
Sbjct: 185 ETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKA 229


>gi|111955326 MLX interacting protein [Homo sapiens]
          Length = 919

 Score = 29.6 bits (65), Expect = 2.6
 Identities = 17/65 (26%), Positives = 29/65 (44%), Gaps = 2/65 (3%)

Query: 120 GKAVEHVFEGEHGTKDEWKGMVLARAPVMDTWF--YITYEKDPVLYMYTLLDDYKDGDLR 177
           GK V   ++   G K +W+  +     +   W+  Y+   K+PV +  T LD   D D  
Sbjct: 139 GKLVSPKWKNFKGLKLQWRDKIRLNNAIWRAWYMQYLEKRKNPVCHFVTPLDGSVDVDEH 198

Query: 178 IIPDS 182
             P++
Sbjct: 199 RRPEA 203


>gi|52485941 integrin, alpha 9 precursor [Homo sapiens]
          Length = 1035

 Score = 28.5 bits (62), Expect = 5.7
 Identities = 22/79 (27%), Positives = 31/79 (39%), Gaps = 11/79 (13%)

Query: 135 DEWKGMVLARAPVMD--------TWFYITYEKDPVL---YMYTLLDDYKDGDLRIIPDSN 183
           DEW G+ LAR P  D         W  I YE D +L   + Y +  + +     +IP   
Sbjct: 122 DEWMGVSLARQPKADGRVLACAHRWKNIYYEADHILPHGFCYIIPSNLQAKGRTLIPCYE 181

Query: 184 YYFPTAEQEPGEVVDSLVG 202
            Y     +E G     + G
Sbjct: 182 EYKKKYGEEHGSCQAGIAG 200


>gi|5454016 retinitis pigmentosa RP1 protein [Homo sapiens]
          Length = 2156

 Score = 27.7 bits (60), Expect = 9.7
 Identities = 13/46 (28%), Positives = 23/46 (50%), Gaps = 6/46 (13%)

Query: 165  YTLLDDYKDGDLRIIPDSNYYF------PTAEQEPGEVVDSLVGKQ 204
            ++ LDD+++  LR   D N Y       P   +EPG + +S+   +
Sbjct: 1414 HSSLDDFENCSLRKFQDENAYTSFDMEEPRTSEEPGSITNSMTSSE 1459


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.140    0.428 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,462,870
Number of Sequences: 37866
Number of extensions: 473401
Number of successful extensions: 1044
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 982
Number of HSP's gapped (non-prelim): 11
length of query: 249
length of database: 18,247,518
effective HSP length: 100
effective length of query: 149
effective length of database: 14,460,918
effective search space: 2154676782
effective search space used: 2154676782
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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