Guide to the Human Genome
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Search of human proteins with 4557289

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4557289 alanine-glyoxylate aminotransferase [Homo sapiens]
         (392 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4557289 alanine-glyoxylate aminotransferase [Homo sapiens]         795   0.0  
gi|31982936 sphingosine-1-phosphate lyase 1 [Homo sapiens]             35   0.12 
gi|126131102 fibrocystin isoform 1 [Homo sapiens]                      34   0.20 
gi|197383062 glutamate decarboxylase-like 1 [Homo sapiens]             34   0.26 
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]             33   0.58 
gi|32307132 NFS1 nitrogen fixation 1 [Homo sapiens]                    33   0.58 
gi|4505255 musashi 1 [Homo sapiens]                                    32   0.76 
gi|21314671 transient receptor potential cation channel, subfami...    30   4.9  
gi|19923812 oxysterol-binding protein-like protein 10 [Homo sapi...    30   4.9  
gi|194294551 cysteine sulfinic acid decarboxylase [Homo sapiens]       30   4.9  
gi|94400919 WD repeat domain 90 [Homo sapiens]                         30   4.9  
gi|4503599 excision repair cross-complementing 1 isofrom 2 [Homo...    29   8.4  
gi|42544169 excision repair cross-complementing 1 isoform 1 [Hom...    29   8.4  

>gi|4557289 alanine-glyoxylate aminotransferase [Homo sapiens]
          Length = 392

 Score =  795 bits (2053), Expect = 0.0
 Identities = 392/392 (100%), Positives = 392/392 (100%)

Query: 1   MASHKLLVTPPKALLKPLSIPNQLLLGPGPSNLPPRIMAAGGLQMIGSMSKDMYQIMDEI 60
           MASHKLLVTPPKALLKPLSIPNQLLLGPGPSNLPPRIMAAGGLQMIGSMSKDMYQIMDEI
Sbjct: 1   MASHKLLVTPPKALLKPLSIPNQLLLGPGPSNLPPRIMAAGGLQMIGSMSKDMYQIMDEI 60

Query: 61  KEGIQYVFQTRNPLTLVISGSGHCALEAALVNVLEPGDSFLVGANGIWGQRAVDIGERIG 120
           KEGIQYVFQTRNPLTLVISGSGHCALEAALVNVLEPGDSFLVGANGIWGQRAVDIGERIG
Sbjct: 61  KEGIQYVFQTRNPLTLVISGSGHCALEAALVNVLEPGDSFLVGANGIWGQRAVDIGERIG 120

Query: 121 ARVHPMTKDPGGHYTLQEVEEGLAQHKPVLLFLTHGESSTGVLQPLDGFGELCHRYKCLL 180
           ARVHPMTKDPGGHYTLQEVEEGLAQHKPVLLFLTHGESSTGVLQPLDGFGELCHRYKCLL
Sbjct: 121 ARVHPMTKDPGGHYTLQEVEEGLAQHKPVLLFLTHGESSTGVLQPLDGFGELCHRYKCLL 180

Query: 181 LVDSVASLGGTPLYMDRQGIDILYSGSQKALNAPPGTSLISFSDKAKKKMYSRKTKPFSF 240
           LVDSVASLGGTPLYMDRQGIDILYSGSQKALNAPPGTSLISFSDKAKKKMYSRKTKPFSF
Sbjct: 181 LVDSVASLGGTPLYMDRQGIDILYSGSQKALNAPPGTSLISFSDKAKKKMYSRKTKPFSF 240

Query: 241 YLDIKWLANFWGCDDQPRMYHHTIPVISLYSLRESLALIAEQGLENSWRQHREAAAYLHG 300
           YLDIKWLANFWGCDDQPRMYHHTIPVISLYSLRESLALIAEQGLENSWRQHREAAAYLHG
Sbjct: 241 YLDIKWLANFWGCDDQPRMYHHTIPVISLYSLRESLALIAEQGLENSWRQHREAAAYLHG 300

Query: 301 RLQALGLQLFVKDPALRLPTVTTVAVPAGYDWRDIVSYVIDHFDIEIMGGLGPSTGKVLR 360
           RLQALGLQLFVKDPALRLPTVTTVAVPAGYDWRDIVSYVIDHFDIEIMGGLGPSTGKVLR
Sbjct: 301 RLQALGLQLFVKDPALRLPTVTTVAVPAGYDWRDIVSYVIDHFDIEIMGGLGPSTGKVLR 360

Query: 361 IGLLGCNATRENVDRVTEALRAALQHCPKKKL 392
           IGLLGCNATRENVDRVTEALRAALQHCPKKKL
Sbjct: 361 IGLLGCNATRENVDRVTEALRAALQHCPKKKL 392


>gi|31982936 sphingosine-1-phosphate lyase 1 [Homo sapiens]
          Length = 568

 Score = 35.0 bits (79), Expect = 0.12
 Identities = 28/100 (28%), Positives = 48/100 (48%), Gaps = 24/100 (24%)

Query: 161 GVLQPLDGFGELCHRYKCLLLVDSVASLGGTPL-YMDR-------------QGIDILYSG 206
           GV+ P+    +L  +YK  L VD  A LGG  + +M++             +G+  + + 
Sbjct: 293 GVIDPVPEVAKLAVKYKIPLHVD--ACLGGFLIVFMEKAGYPLEHPFDFRVKGVTSISAD 350

Query: 207 SQKALNAPPGTSLISFSDKAKKKMYSRKTKPFSFYLDIKW 246
           + K   AP G+SL+ +SDK        K + + F++D  W
Sbjct: 351 THKYGYAPKGSSLVLYSDK--------KYRNYQFFVDTDW 382


>gi|126131102 fibrocystin isoform 1 [Homo sapiens]
          Length = 4074

 Score = 34.3 bits (77), Expect = 0.20
 Identities = 31/119 (26%), Positives = 54/119 (45%), Gaps = 10/119 (8%)

Query: 29   GPSNLPPRIMAAGGLQMIGSMSKDMYQIMDEIKEGIQYVFQTRNPLTLVISGSGHCALEA 88
            G S +PP ++ +  L +  S+  + + IMD +   +  V Q   P+ +    S H AL  
Sbjct: 3511 GESFIPPTLVQSASLLLNESIGANYFNIMDNL---LYVVLQGEEPIEIRSGVSIHLAL-T 3566

Query: 89   ALVNVLEPGDSFLVGANGIWGQRAVDIGERIGARVHPMTKDPGGHYTLQEVEEGLAQHK 147
             +V+VLE G   ++          + IG+     +H M   PG   TL+ + +  A+ K
Sbjct: 3567 VMVSVLEKGWEIVILER---LTNFLQIGQNQIRFIHEM---PGHEETLKAIADSRAKRK 3619


>gi|197383062 glutamate decarboxylase-like 1 [Homo sapiens]
          Length = 521

 Score = 33.9 bits (76), Expect = 0.26
 Identities = 25/68 (36%), Positives = 35/68 (51%), Gaps = 6/68 (8%)

Query: 137 QEVEEGLAQHKPVLLFLTHGESSTGVLQPLDGFGELCHRYKCLLLVDSVASLGGTPLYMD 196
           Q  +EG A   P L+  T G +  G   PLD   ++C R+   L VD  AS GG+ L M 
Sbjct: 258 QARKEGAA---PFLVCATSGTTVLGAFDPLDEIADICERHSLWLHVD--ASWGGSAL-MS 311

Query: 197 RQGIDILY 204
           R+   +L+
Sbjct: 312 RKHRKLLH 319


>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
          Length = 502

 Score = 32.7 bits (73), Expect = 0.58
 Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 4/39 (10%)

Query: 27  GPGPSNLPPRIMAAGGLQMIGSMSKDMYQIMDEIKEGIQ 65
           GP P  LPP ++ AGGL   G        ++D+I++GIQ
Sbjct: 409 GPAPPPLPPALVPAGGLAPGGGRG----ALLDQIRQGIQ 443


>gi|32307132 NFS1 nitrogen fixation 1 [Homo sapiens]
          Length = 457

 Score = 32.7 bits (73), Expect = 0.58
 Identities = 25/104 (24%), Positives = 44/104 (42%), Gaps = 2/104 (1%)

Query: 117 ERIGARVHPMTKDPGGHYTLQEVEEGLAQHKPVLLFLTHGESSTGVLQPLDGFGELCHRY 176
           E  G +V  +     G   L+E+E  +     ++  +T   +  GV QP+   G +C   
Sbjct: 167 EAEGFQVTYLPVQKSGIIDLKELEAAIQPDTSLVSVMTVN-NEIGVKQPIAEIGRICSSR 225

Query: 177 KCLLLVDSVASLGGTPLYMDRQGIDILYSGSQKALNAPPGTSLI 220
           K     D+  ++G  PL ++   ID++     K +  P G   I
Sbjct: 226 KVYFHTDAAQAVGKIPLDVNDMKIDLMSISGHK-IYGPKGVGAI 268


>gi|4505255 musashi 1 [Homo sapiens]
          Length = 362

 Score = 32.3 bits (72), Expect = 0.76
 Identities = 31/132 (23%), Positives = 58/132 (43%), Gaps = 17/132 (12%)

Query: 146 HKPVLLF---LTHGESSTGVLQPLDGFGELCHRYKCLLLVDSVASLG---GTPLYMDRQG 199
           H P  +F   L+   +  G+ +    FGE+    +CL++ D +       G   +MD+ G
Sbjct: 17  HDPCKMFIGGLSWQTTQEGLREYFGQFGEV---KECLVMRDPLTKRSRGFGFVTFMDQAG 73

Query: 200 IDILYSGSQKALNAPPGTSLISFSDKAKKKMYSRKTKPFSFYLDI--------KWLANFW 251
           +D + + S+  L++      ++F  +A+ KM +R  K F   L +        ++   F 
Sbjct: 74  VDKVLAQSRHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKQYFEQFG 133

Query: 252 GCDDQPRMYHHT 263
             DD   M+  T
Sbjct: 134 KVDDAMLMFDKT 145


>gi|21314671 transient receptor potential cation channel, subfamily
           M, member 4 [Homo sapiens]
          Length = 1214

 Score = 29.6 bits (65), Expect = 4.9
 Identities = 33/131 (25%), Positives = 49/131 (37%), Gaps = 21/131 (16%)

Query: 68  FQTRNPLTLVISGSGHCALEAALVNVLEPGDSFLVGANGIW---GQRAVDIGERIGARV- 123
           F+  N +  V+ GSG   L+  L ++L  G      + G W   G     IG  +G  V 
Sbjct: 112 FRAPNLVVSVLGGSGGPVLQTWLQDLLRRGLVRAAQSTGAWIVTGGLHTGIGRHVGVAVR 171

Query: 124 -HPMTKDPGGHYTLQEVEE-GLAQHKPVLL---------FLTHGESSTGVLQPLDGFGEL 172
            H M    G       V   G+ +++  L+         +   G+   GV  PLD     
Sbjct: 172 DHQMASTGGTKVVAMGVAPWGVVRNRDTLINPKGSFPARYRWRGDPEDGVQFPLD----- 226

Query: 173 CHRYKCLLLVD 183
            + Y    LVD
Sbjct: 227 -YNYSAFFLVD 236


>gi|19923812 oxysterol-binding protein-like protein 10 [Homo
           sapiens]
          Length = 764

 Score = 29.6 bits (65), Expect = 4.9
 Identities = 12/29 (41%), Positives = 16/29 (55%)

Query: 124 HPMTKDPGGHYTLQEVEEGLAQHKPVLLF 152
           HPM  DP   Y L+ V E ++ H P+  F
Sbjct: 514 HPMADDPSKSYKLRFVAEQVSHHPPISCF 542


>gi|194294551 cysteine sulfinic acid decarboxylase [Homo sapiens]
          Length = 520

 Score = 29.6 bits (65), Expect = 4.9
 Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 7/76 (9%)

Query: 123 VHPMTKDPGGHYTLQEVEE--GLAQHK---PVLLFLTHGESSTGVLQPLDGFGELCHRYK 177
           V  +  D  G    +++E   G+A+ +   P L+  T G +  G   PL+   ++C R+ 
Sbjct: 235 VRVVKADERGKMVPEDLERQIGMAEAEGAVPFLVSATSGTTVLGAFDPLEAIADVCQRHG 294

Query: 178 CLLLVDSVASLGGTPL 193
             L VD  A+ GG+ L
Sbjct: 295 LWLHVD--AAWGGSVL 308


>gi|94400919 WD repeat domain 90 [Homo sapiens]
          Length = 1748

 Score = 29.6 bits (65), Expect = 4.9
 Identities = 14/28 (50%), Positives = 16/28 (57%)

Query: 7   LVTPPKALLKPLSIPNQLLLGPGPSNLP 34
           L  P K + K  S P  +LLGPGP  LP
Sbjct: 229 LKVPSKPIEKSCSPPEAVLLGPGPQPLP 256


>gi|4503599 excision repair cross-complementing 1 isofrom 2 [Homo
           sapiens]
          Length = 297

 Score = 28.9 bits (63), Expect = 8.4
 Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 9/51 (17%)

Query: 287 SWRQHREAAAYLHGRLQALG---------LQLFVKDPALRLPTVTTVAVPA 328
           S R H     Y+HGRLQ+LG         +Q+ VKDP   L  +  + + A
Sbjct: 142 SLRYHNLHPDYIHGRLQSLGKNFALRVLLVQVDVKDPQQALKELAKMCILA 192


>gi|42544169 excision repair cross-complementing 1 isoform 1 [Homo
           sapiens]
          Length = 323

 Score = 28.9 bits (63), Expect = 8.4
 Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 9/51 (17%)

Query: 287 SWRQHREAAAYLHGRLQALG---------LQLFVKDPALRLPTVTTVAVPA 328
           S R H     Y+HGRLQ+LG         +Q+ VKDP   L  +  + + A
Sbjct: 142 SLRYHNLHPDYIHGRLQSLGKNFALRVLLVQVDVKDPQQALKELAKMCILA 192


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.138    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,197,649
Number of Sequences: 37866
Number of extensions: 739759
Number of successful extensions: 1652
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1647
Number of HSP's gapped (non-prelim): 13
length of query: 392
length of database: 18,247,518
effective HSP length: 104
effective length of query: 288
effective length of database: 14,309,454
effective search space: 4121122752
effective search space used: 4121122752
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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