Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 45430057
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|45430057 Arylsulfatase G [Homo sapiens]
(525 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|45430057 Arylsulfatase G [Homo sapiens] 1093 0.0
gi|146229331 arylsulfatase A isoform a precursor [Homo sapiens] 267 2e-71
gi|146229329 arylsulfatase A isoform a precursor [Homo sapiens] 267 2e-71
gi|146229324 arylsulfatase A isoform a precursor [Homo sapiens] 267 2e-71
gi|6005990 arylsulfatase A isoform a precursor [Homo sapiens] 267 2e-71
gi|4503899 galactosamine (N-acetyl)-6-sulfate sulfatase precurso... 245 8e-65
gi|146229327 arylsulfatase A isoform b [Homo sapiens] 197 2e-50
gi|71852584 arylsulfatase D isoform a precursor [Homo sapiens] 136 5e-32
gi|31742482 arylsulfatase F precursor [Homo sapiens] 134 2e-31
gi|58743319 arylsulfatase family, member H [Homo sapiens] 130 4e-30
gi|71852586 arylsulfatase D isoform b precursor [Homo sapiens] 129 5e-30
gi|109389362 arylsulfatase J [Homo sapiens] 126 6e-29
gi|157266309 arylsulfatase E precursor [Homo sapiens] 124 2e-28
gi|53831991 steryl-sulfatase precursor [Homo sapiens] 123 5e-28
gi|38569407 arylsulfatase B isoform 2 precursor [Homo sapiens] 122 6e-28
gi|38569405 arylsulfatase B isoform 1 precursor [Homo sapiens] 122 6e-28
gi|59797060 arylsulfatase family, member I [Homo sapiens] 119 7e-27
gi|4506919 N-sulfoglucosamine sulfohydrolase precursor [Homo sap... 62 1e-09
gi|4557659 iduronate-2-sulfatase isoform a precursor [Homo sapiens] 62 1e-09
gi|5360208 iduronate-2-sulfatase isoform b precursor [Homo sapiens] 59 1e-08
gi|4504061 glucosamine (N-acetyl)-6-sulfatase precursor [Homo sa... 54 3e-07
gi|240255483 sulfatase 2 isoform a precursor [Homo sapiens] 49 1e-05
gi|240255478 sulfatase 2 isoform b precursor [Homo sapiens] 49 1e-05
gi|29789100 sulfatase 2 isoform a precursor [Homo sapiens] 49 1e-05
gi|189571643 sulfatase 1 [Homo sapiens] 48 3e-05
gi|189571641 sulfatase 1 [Homo sapiens] 48 3e-05
gi|189571638 sulfatase 1 [Homo sapiens] 48 3e-05
gi|189571636 sulfatase 1 [Homo sapiens] 48 3e-05
gi|169217295 PREDICTED: similar to iduronate 2-sulfatase (Hunter... 45 1e-04
gi|39930577 arylsulfatase K [Homo sapiens] 39 0.012
>gi|45430057 Arylsulfatase G [Homo sapiens]
Length = 525
Score = 1093 bits (2826), Expect = 0.0
Identities = 525/525 (100%), Positives = 525/525 (100%)
Query: 1 MGWLFLKVLLAGVSFSGFLYPLVDFCISGKTRGQKPNFVIILADDMGWGDLGANWAETKD 60
MGWLFLKVLLAGVSFSGFLYPLVDFCISGKTRGQKPNFVIILADDMGWGDLGANWAETKD
Sbjct: 1 MGWLFLKVLLAGVSFSGFLYPLVDFCISGKTRGQKPNFVIILADDMGWGDLGANWAETKD 60
Query: 61 TANLDKMASEGMRFVDFHAAASTCSPSRASLLTGRLGLRNGVTRNFAVTSVGGLPLNETT 120
TANLDKMASEGMRFVDFHAAASTCSPSRASLLTGRLGLRNGVTRNFAVTSVGGLPLNETT
Sbjct: 61 TANLDKMASEGMRFVDFHAAASTCSPSRASLLTGRLGLRNGVTRNFAVTSVGGLPLNETT 120
Query: 121 LAEVLQQAGYVTGIIGKWHLGHHGSYHPNFRGFDYYFGIPYSHDMGCTDTPGYNHPPCPA 180
LAEVLQQAGYVTGIIGKWHLGHHGSYHPNFRGFDYYFGIPYSHDMGCTDTPGYNHPPCPA
Sbjct: 121 LAEVLQQAGYVTGIIGKWHLGHHGSYHPNFRGFDYYFGIPYSHDMGCTDTPGYNHPPCPA 180
Query: 181 CPQGDGPSRNLQRDCYTDVALPLYENLNIVEQPVNLSSLAQKYAEKATQFIQRASTSGRP 240
CPQGDGPSRNLQRDCYTDVALPLYENLNIVEQPVNLSSLAQKYAEKATQFIQRASTSGRP
Sbjct: 181 CPQGDGPSRNLQRDCYTDVALPLYENLNIVEQPVNLSSLAQKYAEKATQFIQRASTSGRP 240
Query: 241 FLLYVALAHMHVPLPVTQLPAAPRGRSLYGAGLWEMDSLVGQIKDKVDHTVKENTFLWFT 300
FLLYVALAHMHVPLPVTQLPAAPRGRSLYGAGLWEMDSLVGQIKDKVDHTVKENTFLWFT
Sbjct: 241 FLLYVALAHMHVPLPVTQLPAAPRGRSLYGAGLWEMDSLVGQIKDKVDHTVKENTFLWFT 300
Query: 301 GDNGPWAQKCELAGSVGPFTGFWQTRQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTST 360
GDNGPWAQKCELAGSVGPFTGFWQTRQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTST
Sbjct: 301 GDNGPWAQKCELAGSVGPFTGFWQTRQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTST 360
Query: 361 ALLSVLDIFPTVVALAQASLPQGRRFDGVDVSEVLFGRSQPGHRVLFHPNSGAAGEFGAL 420
ALLSVLDIFPTVVALAQASLPQGRRFDGVDVSEVLFGRSQPGHRVLFHPNSGAAGEFGAL
Sbjct: 361 ALLSVLDIFPTVVALAQASLPQGRRFDGVDVSEVLFGRSQPGHRVLFHPNSGAAGEFGAL 420
Query: 421 QTVRLERYKAFYITGGARACDGSTGPELQHKFPLIFNLEDDTAEAVPLERGGAEYQAVLP 480
QTVRLERYKAFYITGGARACDGSTGPELQHKFPLIFNLEDDTAEAVPLERGGAEYQAVLP
Sbjct: 421 QTVRLERYKAFYITGGARACDGSTGPELQHKFPLIFNLEDDTAEAVPLERGGAEYQAVLP 480
Query: 481 EVRKVLADVLQDIANDNISSADYTQDPSVTPCCNPYQIACRCQAA 525
EVRKVLADVLQDIANDNISSADYTQDPSVTPCCNPYQIACRCQAA
Sbjct: 481 EVRKVLADVLQDIANDNISSADYTQDPSVTPCCNPYQIACRCQAA 525
>gi|146229331 arylsulfatase A isoform a precursor [Homo sapiens]
Length = 507
Score = 267 bits (682), Expect = 2e-71
Identities = 189/507 (37%), Positives = 254/507 (50%), Gaps = 47/507 (9%)
Query: 28 SGKTRGQKPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTCSPS 87
+G + PN V+I ADD+G+GDLG + T NLD++A+ G+RF DF+ S C+PS
Sbjct: 13 AGLAVARPPNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPS 72
Query: 88 RASLLTGRLGLRNGVTRNFAV-TSVGGLPLNETTLAEVLQQAGYVTGIIGKWHL--GHHG 144
RA+LLTGRL +R G+ V +S GGLPL E T+AEVL GY+TG+ GKWHL G G
Sbjct: 73 RAALLTGRLPVRMGMYPGVLVPSSRGGLPLEEVTVAEVLAARGYLTGMAGKWHLGVGPEG 132
Query: 145 SYHPNFRGFDYYFGIPYSHDMG-CTDTPGYNHPPCPACPQGDGPSRNLQRDCYTDVALPL 203
++ P +GF + GIPYSHD G C + + PA P G + L V +PL
Sbjct: 133 AFLPPHQGFHRFLGIPYSHDQGPCQNLTCFP----PATPCDGGCDQGL-------VPIPL 181
Query: 204 YENLNIVEQPVNLSSLAQKYAEKATQFIQRASTSGRPFLLYVALAHMHVPLPVTQLPAAP 263
NL++ QP L L +Y A + A RPF LY A H H P Q A
Sbjct: 182 LANLSVEAQPPWLPGLEARYMAFAHDLMADAQRQDRPFFLYYASHHTHYPQFSGQSFAER 241
Query: 264 RGRSLYGAGLWEMDSLVGQIKDKV-DHTVKENTFLWFTGDNGPWAQKCELAGSVGPFTGF 322
GR +G L E+D+ VG + + D + E T + FT DNGP + G G
Sbjct: 242 SGRGPFGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCSG----- 296
Query: 323 WQTRQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSTALLSVLDIFPTVVALAQASLPQ 382
R G K TT+EGG R PALA+WPG + VT L S LD+ PT+ ALA A LP
Sbjct: 297 -LLRCG----KGTTYEGGVREPALAFWPGHIAPGVTH-ELASSLDLLPTLAALAGAPLP- 349
Query: 383 GRRFDGVDVSEVLFGRSQ-PGHRVLFHPNSGAAGEFGALQTVRLERYKAFYITGGARACD 441
DG D+S +L G + P + F+P+ E + VR +YKA + T G+ D
Sbjct: 350 NVTLDGFDLSPLLLGTGKSPRQSLFFYPS--YPDEVRGVFAVRTGKYKAHFFTQGSAHSD 407
Query: 442 GSTGPELQ-------HKFPLIFNLEDDTAEAVPLERGGAEYQAVLPEVRKVLADV----- 489
+ P H+ PL+++L D E L G A PEV + L +
Sbjct: 408 TTADPACHASSSLTAHEPPLLYDLSKDPGENYNLLGGVA---GATPEVLQALKQLQLLKA 464
Query: 490 -LQDIANDNISSADYTQDPSVTPCCNP 515
L S +DP++ CC+P
Sbjct: 465 QLDAAVTFGPSQVARGEDPALQICCHP 491
>gi|146229329 arylsulfatase A isoform a precursor [Homo sapiens]
Length = 507
Score = 267 bits (682), Expect = 2e-71
Identities = 189/507 (37%), Positives = 254/507 (50%), Gaps = 47/507 (9%)
Query: 28 SGKTRGQKPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTCSPS 87
+G + PN V+I ADD+G+GDLG + T NLD++A+ G+RF DF+ S C+PS
Sbjct: 13 AGLAVARPPNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPS 72
Query: 88 RASLLTGRLGLRNGVTRNFAV-TSVGGLPLNETTLAEVLQQAGYVTGIIGKWHL--GHHG 144
RA+LLTGRL +R G+ V +S GGLPL E T+AEVL GY+TG+ GKWHL G G
Sbjct: 73 RAALLTGRLPVRMGMYPGVLVPSSRGGLPLEEVTVAEVLAARGYLTGMAGKWHLGVGPEG 132
Query: 145 SYHPNFRGFDYYFGIPYSHDMG-CTDTPGYNHPPCPACPQGDGPSRNLQRDCYTDVALPL 203
++ P +GF + GIPYSHD G C + + PA P G + L V +PL
Sbjct: 133 AFLPPHQGFHRFLGIPYSHDQGPCQNLTCFP----PATPCDGGCDQGL-------VPIPL 181
Query: 204 YENLNIVEQPVNLSSLAQKYAEKATQFIQRASTSGRPFLLYVALAHMHVPLPVTQLPAAP 263
NL++ QP L L +Y A + A RPF LY A H H P Q A
Sbjct: 182 LANLSVEAQPPWLPGLEARYMAFAHDLMADAQRQDRPFFLYYASHHTHYPQFSGQSFAER 241
Query: 264 RGRSLYGAGLWEMDSLVGQIKDKV-DHTVKENTFLWFTGDNGPWAQKCELAGSVGPFTGF 322
GR +G L E+D+ VG + + D + E T + FT DNGP + G G
Sbjct: 242 SGRGPFGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCSG----- 296
Query: 323 WQTRQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSTALLSVLDIFPTVVALAQASLPQ 382
R G K TT+EGG R PALA+WPG + VT L S LD+ PT+ ALA A LP
Sbjct: 297 -LLRCG----KGTTYEGGVREPALAFWPGHIAPGVTH-ELASSLDLLPTLAALAGAPLP- 349
Query: 383 GRRFDGVDVSEVLFGRSQ-PGHRVLFHPNSGAAGEFGALQTVRLERYKAFYITGGARACD 441
DG D+S +L G + P + F+P+ E + VR +YKA + T G+ D
Sbjct: 350 NVTLDGFDLSPLLLGTGKSPRQSLFFYPS--YPDEVRGVFAVRTGKYKAHFFTQGSAHSD 407
Query: 442 GSTGPELQ-------HKFPLIFNLEDDTAEAVPLERGGAEYQAVLPEVRKVLADV----- 489
+ P H+ PL+++L D E L G A PEV + L +
Sbjct: 408 TTADPACHASSSLTAHEPPLLYDLSKDPGENYNLLGGVA---GATPEVLQALKQLQLLKA 464
Query: 490 -LQDIANDNISSADYTQDPSVTPCCNP 515
L S +DP++ CC+P
Sbjct: 465 QLDAAVTFGPSQVARGEDPALQICCHP 491
>gi|146229324 arylsulfatase A isoform a precursor [Homo sapiens]
Length = 507
Score = 267 bits (682), Expect = 2e-71
Identities = 189/507 (37%), Positives = 254/507 (50%), Gaps = 47/507 (9%)
Query: 28 SGKTRGQKPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTCSPS 87
+G + PN V+I ADD+G+GDLG + T NLD++A+ G+RF DF+ S C+PS
Sbjct: 13 AGLAVARPPNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPS 72
Query: 88 RASLLTGRLGLRNGVTRNFAV-TSVGGLPLNETTLAEVLQQAGYVTGIIGKWHL--GHHG 144
RA+LLTGRL +R G+ V +S GGLPL E T+AEVL GY+TG+ GKWHL G G
Sbjct: 73 RAALLTGRLPVRMGMYPGVLVPSSRGGLPLEEVTVAEVLAARGYLTGMAGKWHLGVGPEG 132
Query: 145 SYHPNFRGFDYYFGIPYSHDMG-CTDTPGYNHPPCPACPQGDGPSRNLQRDCYTDVALPL 203
++ P +GF + GIPYSHD G C + + PA P G + L V +PL
Sbjct: 133 AFLPPHQGFHRFLGIPYSHDQGPCQNLTCFP----PATPCDGGCDQGL-------VPIPL 181
Query: 204 YENLNIVEQPVNLSSLAQKYAEKATQFIQRASTSGRPFLLYVALAHMHVPLPVTQLPAAP 263
NL++ QP L L +Y A + A RPF LY A H H P Q A
Sbjct: 182 LANLSVEAQPPWLPGLEARYMAFAHDLMADAQRQDRPFFLYYASHHTHYPQFSGQSFAER 241
Query: 264 RGRSLYGAGLWEMDSLVGQIKDKV-DHTVKENTFLWFTGDNGPWAQKCELAGSVGPFTGF 322
GR +G L E+D+ VG + + D + E T + FT DNGP + G G
Sbjct: 242 SGRGPFGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCSG----- 296
Query: 323 WQTRQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSTALLSVLDIFPTVVALAQASLPQ 382
R G K TT+EGG R PALA+WPG + VT L S LD+ PT+ ALA A LP
Sbjct: 297 -LLRCG----KGTTYEGGVREPALAFWPGHIAPGVTH-ELASSLDLLPTLAALAGAPLP- 349
Query: 383 GRRFDGVDVSEVLFGRSQ-PGHRVLFHPNSGAAGEFGALQTVRLERYKAFYITGGARACD 441
DG D+S +L G + P + F+P+ E + VR +YKA + T G+ D
Sbjct: 350 NVTLDGFDLSPLLLGTGKSPRQSLFFYPS--YPDEVRGVFAVRTGKYKAHFFTQGSAHSD 407
Query: 442 GSTGPELQ-------HKFPLIFNLEDDTAEAVPLERGGAEYQAVLPEVRKVLADV----- 489
+ P H+ PL+++L D E L G A PEV + L +
Sbjct: 408 TTADPACHASSSLTAHEPPLLYDLSKDPGENYNLLGGVA---GATPEVLQALKQLQLLKA 464
Query: 490 -LQDIANDNISSADYTQDPSVTPCCNP 515
L S +DP++ CC+P
Sbjct: 465 QLDAAVTFGPSQVARGEDPALQICCHP 491
>gi|6005990 arylsulfatase A isoform a precursor [Homo sapiens]
Length = 507
Score = 267 bits (682), Expect = 2e-71
Identities = 189/507 (37%), Positives = 254/507 (50%), Gaps = 47/507 (9%)
Query: 28 SGKTRGQKPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTCSPS 87
+G + PN V+I ADD+G+GDLG + T NLD++A+ G+RF DF+ S C+PS
Sbjct: 13 AGLAVARPPNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPS 72
Query: 88 RASLLTGRLGLRNGVTRNFAV-TSVGGLPLNETTLAEVLQQAGYVTGIIGKWHL--GHHG 144
RA+LLTGRL +R G+ V +S GGLPL E T+AEVL GY+TG+ GKWHL G G
Sbjct: 73 RAALLTGRLPVRMGMYPGVLVPSSRGGLPLEEVTVAEVLAARGYLTGMAGKWHLGVGPEG 132
Query: 145 SYHPNFRGFDYYFGIPYSHDMG-CTDTPGYNHPPCPACPQGDGPSRNLQRDCYTDVALPL 203
++ P +GF + GIPYSHD G C + + PA P G + L V +PL
Sbjct: 133 AFLPPHQGFHRFLGIPYSHDQGPCQNLTCFP----PATPCDGGCDQGL-------VPIPL 181
Query: 204 YENLNIVEQPVNLSSLAQKYAEKATQFIQRASTSGRPFLLYVALAHMHVPLPVTQLPAAP 263
NL++ QP L L +Y A + A RPF LY A H H P Q A
Sbjct: 182 LANLSVEAQPPWLPGLEARYMAFAHDLMADAQRQDRPFFLYYASHHTHYPQFSGQSFAER 241
Query: 264 RGRSLYGAGLWEMDSLVGQIKDKV-DHTVKENTFLWFTGDNGPWAQKCELAGSVGPFTGF 322
GR +G L E+D+ VG + + D + E T + FT DNGP + G G
Sbjct: 242 SGRGPFGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPETMRMSRGGCSG----- 296
Query: 323 WQTRQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSTALLSVLDIFPTVVALAQASLPQ 382
R G K TT+EGG R PALA+WPG + VT L S LD+ PT+ ALA A LP
Sbjct: 297 -LLRCG----KGTTYEGGVREPALAFWPGHIAPGVTH-ELASSLDLLPTLAALAGAPLP- 349
Query: 383 GRRFDGVDVSEVLFGRSQ-PGHRVLFHPNSGAAGEFGALQTVRLERYKAFYITGGARACD 441
DG D+S +L G + P + F+P+ E + VR +YKA + T G+ D
Sbjct: 350 NVTLDGFDLSPLLLGTGKSPRQSLFFYPS--YPDEVRGVFAVRTGKYKAHFFTQGSAHSD 407
Query: 442 GSTGPELQ-------HKFPLIFNLEDDTAEAVPLERGGAEYQAVLPEVRKVLADV----- 489
+ P H+ PL+++L D E L G A PEV + L +
Sbjct: 408 TTADPACHASSSLTAHEPPLLYDLSKDPGENYNLLGGVA---GATPEVLQALKQLQLLKA 464
Query: 490 -LQDIANDNISSADYTQDPSVTPCCNP 515
L S +DP++ CC+P
Sbjct: 465 QLDAAVTFGPSQVARGEDPALQICCHP 491
>gi|4503899 galactosamine (N-acetyl)-6-sulfate sulfatase precursor
[Homo sapiens]
Length = 522
Score = 245 bits (625), Expect = 8e-65
Identities = 176/490 (35%), Positives = 244/490 (49%), Gaps = 83/490 (16%)
Query: 34 QKPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTCSPSRASLLT 93
Q PN +++L DDMGWGDLG +++T NLD+MA+EG+ F +F++A CSPSRA+LLT
Sbjct: 29 QPPNILLLLMDDMGWGDLGVYGEPSRETPNLDRMAAEGLLFPNFYSANPLCSPSRAALLT 88
Query: 94 GRLGLRNG-VTRNFAVTS-------VGGLPLNETTLAEVLQQAGYVTGIIGKWHLGHHGS 145
GRL +RNG T N + VGG+P +E L E+L++AGYV+ I+GKWHLGH
Sbjct: 89 GRLPIRNGFYTTNAHARNAYTPQEIVGGIPDSEQLLPELLKKAGYVSKIVGKWHLGHRPQ 148
Query: 146 YHPNFRGFDYYFGIPYSHDMGCTDTPGYNHPPCPACPQGDGPSRNLQRDCYTDVALPLYE 205
+HP GFD +FG P H GP N R +P+Y
Sbjct: 149 FHPLKHGFDEWFGSPNCH---------------------FGPYDNKARP-----NIPVYR 182
Query: 206 NLNIV-----EQPVNL----SSLAQKYAEKATQFIQRASTSGRPFLLYVALAHMHVPLPV 256
+ +V E P+NL ++L Q Y ++A FI+R + PF LY A+ H P+
Sbjct: 183 DWEMVGRYYEEFPINLKTGEANLTQIYLQEALDFIKRQARH-HPFFLYWAVDATHAPVYA 241
Query: 257 TQ--LPAAPRGRSLYGAGLWEMDSLVGQIKDKV-DHTVKENTFLWFTGDNG-PWAQKCEL 312
++ L + RGR YG + E+D +G+I + + D V +NTF++FT DNG E
Sbjct: 242 SKPFLGTSQRGR--YGDAVREIDDSIGKILELLQDLHVADNTFVFFTSDNGAALISAPEQ 299
Query: 313 AGSVGPFTGFWQTRQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSTALLSVLDIFPTV 372
GS GPF KQTT+EGG R PALA+WPG V S L S++D+F T
Sbjct: 300 GGSNGPFL----------CGKQTTFEGGMREPALAWWPGHVTAGQVSHQLGSIMDLFTTS 349
Query: 373 VALAQASLPQGRRFDGVDVSEVLFGRSQPGHRVLFHPNSGAAGEFGALQTVRLERYKAFY 432
+ALA + P R DG+++ L + ++ L L ++KA +
Sbjct: 350 LALAGLTPPSDRAIDGLNLLPTLLQGRLMDRPIFYYRGD-------TLMAATLGQHKAHF 402
Query: 433 IT---------GGARACDGST-------GPELQHKFPLIFNLEDDTAEAVPLERGGAEYQ 476
T G C G E K PLIF+L D E PL AEYQ
Sbjct: 403 WTWTNSWENFRQGIDFCPGQNVSGVTTHNLEDHTKLPLIFHLGRDPGERFPLSFASAEYQ 462
Query: 477 AVLPEVRKVL 486
L + V+
Sbjct: 463 EALSRITSVV 472
>gi|146229327 arylsulfatase A isoform b [Homo sapiens]
Length = 423
Score = 197 bits (501), Expect = 2e-50
Identities = 151/425 (35%), Positives = 201/425 (47%), Gaps = 46/425 (10%)
Query: 109 TSVGGLPLNETTLAEVLQQAGYVTGIIGKWHLG--HHGSYHPNFRGFDYYFGIPYSHDMG 166
+S GGLPL E T+AEVL GY+TG+ GKWHLG G++ P +GF + GIPYSHD G
Sbjct: 11 SSRGGLPLEEVTVAEVLAARGYLTGMAGKWHLGVGPEGAFLPPHQGFHRFLGIPYSHDQG 70
Query: 167 -CTDTPGYNHPPCPACPQGDGPSRNLQRDCYTDVALPLYENLNIVEQPVNLSSLAQKYAE 225
C + + PA P G + L V +PL NL++ QP L L +Y
Sbjct: 71 PCQNLTCFP----PATPCDGGCDQGL-------VPIPLLANLSVEAQPPWLPGLEARYMA 119
Query: 226 KATQFIQRASTSGRPFLLYVALAHMHVPLPVTQLPAAPRGRSLYGAGLWEMDSLVGQIKD 285
A + A RPF LY A H H P Q A GR +G L E+D+ VG +
Sbjct: 120 FAHDLMADAQRQDRPFFLYYASHHTHYPQFSGQSFAERSGRGPFGDSLMELDAAVGTLMT 179
Query: 286 KV-DHTVKENTFLWFTGDNGPWAQKCELAGSVGPFTGFWQTRQGGSPAKQTTWEGGHRVP 344
+ D + E T + FT DNGP + G G R G K TT+EGG R P
Sbjct: 180 AIGDLGLLEETLVIFTADNGPETMRMSRGGCSG------LLRCG----KGTTYEGGVREP 229
Query: 345 ALAYWPGRVPVNVTSTALLSVLDIFPTVVALAQASLPQGRRFDGVDVSEVLFGRSQ-PGH 403
ALA+WPG + VT L S LD+ PT+ ALA A LP DG D+S +L G + P
Sbjct: 230 ALAFWPGHIAPGVTH-ELASSLDLLPTLAALAGAPLP-NVTLDGFDLSPLLLGTGKSPRQ 287
Query: 404 RVLFHPNSGAAGEFGALQTVRLERYKAFYITGGARACDGSTGPELQ-------HKFPLIF 456
+ F+P+ E + VR +YKA + T G+ D + P H+ PL++
Sbjct: 288 SLFFYPS--YPDEVRGVFAVRTGKYKAHFFTQGSAHSDTTADPACHASSSLTAHEPPLLY 345
Query: 457 NLEDDTAEAVPLERGGAEYQAVLPEVRKVLADV------LQDIANDNISSADYTQDPSVT 510
+L D E L G A PEV + L + L S +DP++
Sbjct: 346 DLSKDPGENYNLLGGVA---GATPEVLQALKQLQLLKAQLDAAVTFGPSQVARGEDPALQ 402
Query: 511 PCCNP 515
CC+P
Sbjct: 403 ICCHP 407
>gi|71852584 arylsulfatase D isoform a precursor [Homo sapiens]
Length = 593
Score = 136 bits (342), Expect = 5e-32
Identities = 101/336 (30%), Positives = 157/336 (46%), Gaps = 24/336 (7%)
Query: 203 LYENLNIVEQPVNLSSLAQKYAEKATQFIQRASTSGRPFLLYVALAHMHVPLPVTQLPAA 262
L N ++ EQP+ L A ++A +I+R PFLL+++L H+H+PL T
Sbjct: 258 LMRNHDVTEQPMVLEKTASLMLKEAVSYIERHKHG--PFLLFLSLLHVHIPLVTTSAFLG 315
Query: 263 PRGRSLYGAGLWEMDSLVGQIKDKV-DHTVKENTFLWFTGDNGPWAQKCELAGSVGPFTG 321
LYG + EMD L+G++ + + D+ +K +TF +FT D+G + + +G + G
Sbjct: 316 KSQHGLYGDNVEEMDWLIGKVLNAIEDNGLKNSTFTYFTSDHGGHLEARDGHSQLGGWNG 375
Query: 322 FWQTRQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSTALLSVLDIFPTVVALAQASLP 381
++ +G WEGG RVP + +WPG +P S++D+FPTVV L +P
Sbjct: 376 IYKGGKG-----MGGWEGGIRVPGIFHWPGVLPAGRVIGEPTSLMDVFPTVVQLVGGEVP 430
Query: 382 QGRRFDGVDVSEVLFG-RSQPGHRVLFHPNSGAAGEFGALQTVRLERYKAFYIT-----G 435
Q R DG + +L G ++ H LFH Q +K Y T
Sbjct: 431 QDRVIDGHSLVPLLQGAEARSAHEFLFHYCGQHLHAARWHQKDSGSVWKVHYTTPQFHPE 490
Query: 436 GARACDG------STGPELQHKFPLIFNLEDDTAEAVPLERGGAE-YQAVLPEVRKVLAD 488
GA AC G S H+ PL+F+L D +EA PL Y AV+ V +++
Sbjct: 491 GAGACYGRGVCPCSGEGVTHHRPPLLFDLSRDPSEARPLTPDSEPLYHAVIARVGAAVSE 550
Query: 489 VLQDIA--NDNISSADYTQDPSVTPCCNPYQIACRC 522
Q ++ S ++ P + PCC + C C
Sbjct: 551 HRQTLSPVPQQFSMSNILWKPWLQPCCGHFPF-CSC 585
Score = 129 bits (325), Expect = 5e-30
Identities = 69/162 (42%), Positives = 95/162 (58%), Gaps = 12/162 (7%)
Query: 18 FLYPLVDFCISGKTRGQKPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDF 77
FL L+ C KPN ++I+ADD+G GDLG T T N+D++A EG+R
Sbjct: 23 FLCLLLKTCEPKTANAFKPNILLIMADDLGTGDLGCYGNNTLRTPNIDQLAEEGVRLTQH 82
Query: 78 HAAASTCSPSRASLLTGRLGLRNGVTRNFAVTSV------GGLPLNETTLAEVLQQAGYV 131
AAA C+PSRA+ LTGR R+G+ + ++ GGLP NETT A +LQQ GY
Sbjct: 83 LAAAPLCTPSRAAFLTGRHSFRSGMDASNGYRALQWNAGSGGLPENETTFARILQQHGYA 142
Query: 132 TGIIGKWHLGHHGS------YHPNFRGFDYYFGIPYSHDMGC 167
TG+IGKWH G + + +HP GFDY++G+P++ C
Sbjct: 143 TGLIGKWHQGVNCASRGDHCHHPLNHGFDYFYGMPFTLTNDC 184
>gi|31742482 arylsulfatase F precursor [Homo sapiens]
Length = 590
Score = 134 bits (338), Expect = 2e-31
Identities = 73/174 (41%), Positives = 103/174 (59%), Gaps = 16/174 (9%)
Query: 15 FSGFLYPLVDFCISGKTRGQKPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRF 74
F + L++ C + + KPN V+I+ DD+G GDLG +T T ++D++A EG+R
Sbjct: 9 FMSLVCALLNTCQAHRVHDDKPNIVLIMVDDLGIGDLGCYGNDTMRTPHIDRLAREGVRL 68
Query: 75 VDFHAAASTCSPSRASLLTGRLGLRNG--------VTRNFAVTSVGGLPLNETTLAEVLQ 126
+AAS CSPSR++ LTGR +R+G V +N AV + GLPLNETTLA +L+
Sbjct: 69 TQHISAASLCSPSRSAFLTGRYPIRSGMVSSGNRRVIQNLAVPA--GLPLNETTLAALLK 126
Query: 127 QAGYVTGIIGKWHLG------HHGSYHPNFRGFDYYFGIPYSHDMGCTDTPGYN 174
+ GY TG+IGKWH G +HP GFDYY+G+P++ C P N
Sbjct: 127 KQGYSTGLIGKWHQGLNCDSRSDQCHHPYNYGFDYYYGMPFTLVDSCWPDPSRN 180
Score = 125 bits (314), Expect = 9e-29
Identities = 100/336 (29%), Positives = 150/336 (44%), Gaps = 36/336 (10%)
Query: 209 IVEQPVNLSSLAQKYAEKATQFIQRASTSGRPFLLYVALAHMHVPLPVTQLPAAPRGRSL 268
I EQP+ ++A F++R S FLL+ + H+H PLP T L
Sbjct: 253 ITEQPMKAERAGSIMVKEAISFLERHSKE--TFLLFFSFLHVHTPLPTTDDFTGTSKHGL 310
Query: 269 YGAGLWEMDSLVGQIKDKVDHT-VKENTFLWFTGDNGPWAQKCELAGSVGPFTGFWQTRQ 327
YG + EMDS+VG+I D +D ++ NT ++FT D+G + +G + G ++ +
Sbjct: 311 YGDNVEEMDSMVGKILDAIDDFGLRNNTLVYFTSDHGGHLEARRGHAQLGGWNGIYKGGK 370
Query: 328 GGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSTALLSVLDIFPTVVALAQASLPQGRRFD 387
G WEGG RVP + WPG+VP S++DI PTV +++ SLPQ R D
Sbjct: 371 G-----MGGWEGGIRVPGIVRWPGKVPAGRLIKEPTSLMDILPTVASVSGGSLPQDRVID 425
Query: 388 GVDVSEVLFGRSQPG-HRVLFHPNSGAAGEFGALQTVRL-------ERYKAFYIT----- 434
G D+ +L G + H LFH G + L VR +KA Y+T
Sbjct: 426 GRDLMPLLQGNVRHSEHEFLFH----YCGSY--LHAVRWIPKDDSGSVWKAHYVTPVFQP 479
Query: 435 ---GG---ARACDGSTGPELQHKFPLIFNLEDDTAEAVPLERGGAE-YQAVLPEVRKVLA 487
GG C H PL+F+L D +E+ PL + V+ +V L
Sbjct: 480 PASGGCYVTSLCRCFGEQVTYHNPPLLFDLSRDPSESTPLTPATEPLHDFVIKKVANALK 539
Query: 488 DVLQDIANDNISSADYTQDPS-VTPCCNPYQIACRC 522
+ + I ++ Q + + PCC + C C
Sbjct: 540 EHQETIVPVTYQLSELNQGRTWLKPCCGVFPF-CLC 574
>gi|58743319 arylsulfatase family, member H [Homo sapiens]
Length = 562
Score = 130 bits (326), Expect = 4e-30
Identities = 68/156 (43%), Positives = 94/156 (60%), Gaps = 15/156 (9%)
Query: 31 TRGQKPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTCSPSRAS 90
TR +PN V+++ADD+G GDL + T N+D++ASEG+R AAAS C+PSRA+
Sbjct: 2 TRNARPNIVLLMADDLGVGDLCCYGNNSVSTPNIDRLASEGVRLTQHLAAASMCTPSRAA 61
Query: 91 LLTGRLGLRNGVTRNFAVTSV-------GGLPLNETTLAEVLQQAGYVTGIIGKWHLG-- 141
LTGR +R+G+ + + GGLP NETT A++LQ GY TG+IGKWHLG
Sbjct: 62 FLTGRYPIRSGMVSAYNLNRAFTWLGGSGGLPTNETTFAKLLQHRGYRTGLIGKWHLGLS 121
Query: 142 ----HHGSYHPNFRGFDYYFGIPYS--HDMGCTDTP 171
+ YHP GF Y++G+P+ D + TP
Sbjct: 122 CASRNDHCYHPLNHGFHYFYGVPFGLLSDCQASKTP 157
Score = 122 bits (305), Expect = 1e-27
Identities = 102/346 (29%), Positives = 155/346 (44%), Gaps = 45/346 (13%)
Query: 203 LYENLNIVEQPVNLSSLAQKYAEKATQFIQRASTSGRPFLLYVALAHMHVPLPVTQLPAA 262
L N I++QP+ +A ++A FI+R PFLL+ + H+H PL +
Sbjct: 225 LMRNHEIIQQPMKEEKVASLMLKEALAFIERYKRE--PFLLFFSFLHVHTPLISKKKFVG 282
Query: 263 PRGRSLYGAGLWEMDSLVGQIKDKVDHT-VKENTFLWFTGDNGPWAQKCELAGSVGPFTG 321
YG + EMD +VG+I D +D + +T ++FT DNG + + A +G + G
Sbjct: 283 RSKYGRYGDNVEEMDWMVGKILDALDQERLANHTLVYFTSDNGGHLEPLDGAVQLGGWNG 342
Query: 322 FWQTRQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSTALLSVLDIFPTVVALAQASLP 381
++ +G WEGG RVP + WP + S++DI+PT+ + L
Sbjct: 343 IYKGGKG-----MGGWEGGIRVPGIFRWPSVLEAGRVINEPTSLMDIYPTLSYIGGGILS 397
Query: 382 QGRRFDGVDVSEVLFGR-SQPGHRVLFHPNSGAAGEFGALQTVRLER------YKAFYIT 434
Q R DG ++ +L GR S H LFH G + L TVR + +KA Y+T
Sbjct: 398 QDRVIDGQNLMPLLEGRASHSDHEFLFH----YCGVY--LHTVRWHQKDCATVWKAHYVT 451
Query: 435 -----GGARACDGS-----TGPELQHKFPLIFNLEDDTAEAVPLERGG--------AEYQ 476
G AC GS +G H PL+F++ D +EA+PL + +
Sbjct: 452 PKFYPEGTGACYGSGICSCSGDVTYHDPPLLFDISRDPSEALPLNPDNEPLFDSVIKKME 511
Query: 477 AVLPEVRKVLADVLQDIANDNISSADYTQDPSVTPCCNPYQIACRC 522
A + E R+ L V Q + N P + PCC + C C
Sbjct: 512 AAIREHRRTLTPVPQQFSVFNT-----IWKPWLQPCCGTFPF-CGC 551
>gi|71852586 arylsulfatase D isoform b precursor [Homo sapiens]
Length = 382
Score = 129 bits (325), Expect = 5e-30
Identities = 69/162 (42%), Positives = 95/162 (58%), Gaps = 12/162 (7%)
Query: 18 FLYPLVDFCISGKTRGQKPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDF 77
FL L+ C KPN ++I+ADD+G GDLG T T N+D++A EG+R
Sbjct: 23 FLCLLLKTCEPKTANAFKPNILLIMADDLGTGDLGCYGNNTLRTPNIDQLAEEGVRLTQH 82
Query: 78 HAAASTCSPSRASLLTGRLGLRNGVTRNFAVTSV------GGLPLNETTLAEVLQQAGYV 131
AAA C+PSRA+ LTGR R+G+ + ++ GGLP NETT A +LQQ GY
Sbjct: 83 LAAAPLCTPSRAAFLTGRHSFRSGMDASNGYRALQWNAGSGGLPENETTFARILQQHGYA 142
Query: 132 TGIIGKWHLGHHGS------YHPNFRGFDYYFGIPYSHDMGC 167
TG+IGKWH G + + +HP GFDY++G+P++ C
Sbjct: 143 TGLIGKWHQGVNCASRGDHCHHPLNHGFDYFYGMPFTLTNDC 184
Score = 49.7 bits (117), Expect = 7e-06
Identities = 27/78 (34%), Positives = 41/78 (52%), Gaps = 2/78 (2%)
Query: 203 LYENLNIVEQPVNLSSLAQKYAEKATQFIQRASTSGRPFLLYVALAHMHVPLPVTQLPAA 262
L N ++ EQP+ L A ++A +I+R PFLL+++L H+H+PL T
Sbjct: 258 LMRNHDVTEQPMVLEKTASLMLKEAVSYIERHKHG--PFLLFLSLLHVHIPLVTTSAFLG 315
Query: 263 PRGRSLYGAGLWEMDSLV 280
LYG + EMD L+
Sbjct: 316 KSQHGLYGDNVEEMDWLI 333
>gi|109389362 arylsulfatase J [Homo sapiens]
Length = 599
Score = 126 bits (316), Expect = 6e-29
Identities = 107/377 (28%), Positives = 169/377 (44%), Gaps = 52/377 (13%)
Query: 31 TRGQKPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTCSPSRAS 90
T +P+ + ILADD G+ D+G + +E K T LDK+A+EG++ +++ C+PSR+
Sbjct: 71 TSTSQPHLIFILADDQGFRDVGYHGSEIK-TPTLDKLAAEGVKLENYYVQP-ICTPSRSQ 128
Query: 91 LLTGRLGLRNGVTRNFA-VTSVGGLPLNETTLAEVLQQAGYVTGIIGKWHLG-HHGSYHP 148
+TG+ + G+ + T LPL+ TL + L++ GY T ++GKWHLG + P
Sbjct: 129 FITGKYQIHTGLQHSIIRPTQPNCLPLDNATLPQKLKEVGYSTHMVGKWHLGFYRKECMP 188
Query: 149 NFRGFDYYFGIPYSHDMGCTDTPGYNHPPCPACPQGDGPSRNLQRDCYTDVALPLYENLN 208
RGFD +FG +G D Y H C D P C D LYEN N
Sbjct: 189 TRRGFDTFFG----SLLGSGDY--YTHYKC------DSPGM-----CGYD----LYENDN 227
Query: 209 IVEQPVNLSSLAQKYAEKATQFIQRASTSGRPFLLYVALAHMHVPLPVTQLPA------- 261
N Q Y ++ Q + + + +P LY+A +H PL Q P
Sbjct: 228 AAWDYDNGIYSTQMYTQRVQQILASHNPT-KPIFLYIAYQAVHSPL---QAPGRYFEHYR 283
Query: 262 --APRGRSLYGAGLWEMDSLVGQIKDKV-DHTVKENTFLWFTGDNGPWAQKCELAGSVGP 318
R Y A L +D + + + + N+ + ++ DNG + GS P
Sbjct: 284 SIININRRRYAAMLSCLDEAINNVTLALKTYGFYNNSIIIYSSDNG---GQPTAGGSNWP 340
Query: 319 FTGFWQTRQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSTALLSVLDIFPTVVALAQA 378
G +K T WEGG R + P L+ + D +PT+++LA+
Sbjct: 341 LRG----------SKGTYWEGGIRAVGFVHSPLLKNKGTVCKELVHITDWYPTLISLAEG 390
Query: 379 SLPQGRRFDGVDVSEVL 395
+ + + DG D+ E +
Sbjct: 391 QIDEDIQLDGYDIWETI 407
>gi|157266309 arylsulfatase E precursor [Homo sapiens]
Length = 589
Score = 124 bits (312), Expect = 2e-28
Identities = 59/147 (40%), Positives = 91/147 (61%), Gaps = 12/147 (8%)
Query: 28 SGKTRGQKPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTCSPS 87
S +PN ++++ADD+G GD+G T T N+D++A +G++ +AAS C+PS
Sbjct: 30 SSDISASRPNILLLMADDLGIGDIGCYGNNTMRTPNIDRLAEDGVKLTQHISAASLCTPS 89
Query: 88 RASLLTGRLGLRNGVTRNFA------VTSVGGLPLNETTLAEVLQQAGYVTGIIGKWHLG 141
RA+ LTGR +R+G+ + + GGLP NETT A++L++ GY TG+IGKWHLG
Sbjct: 90 RAAFLTGRYPVRSGMVSSIGYRVLQWTGASGGLPTNETTFAKILKEKGYATGLIGKWHLG 149
Query: 142 ------HHGSYHPNFRGFDYYFGIPYS 162
+HP GFD+++G+P+S
Sbjct: 150 LNCESASDHCHHPLHHGFDHFYGMPFS 176
Score = 114 bits (286), Expect = 2e-25
Identities = 96/345 (27%), Positives = 150/345 (43%), Gaps = 30/345 (8%)
Query: 194 DCYTDVALPLYENLNIVEQPVNLSSLAQKYAEKATQFIQRASTSGRPFLLYVALAHMHVP 253
DC+ L N I EQP+ ++ F++R PFLL+V+ H+H+P
Sbjct: 252 DCF------LMRNHTITEQPMCFQRTTPLILQEVASFLKRNKHG--PFLLFVSFLHVHIP 303
Query: 254 LPVTQLPAAPRGRSLYGAGLWEMDSLVGQIKDKVD-HTVKENTFLWFTGDNGPWAQKCEL 312
L + LYG + EMD +VG+I D +D + +T ++FT D+G +
Sbjct: 304 LITMENFLGKSLHGLYGDNVEEMDWMVGRILDTLDVEGLSNSTLIYFTSDHGGSLENQLG 363
Query: 313 AGSVGPFTGFWQTRQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSTALLSVLDIFPTV 372
G + G ++ +G WEGG RVP + WPG +P S++D+FPTV
Sbjct: 364 NTQYGGWNGIYKGGKG-----MGGWEGGIRVPGIFRWPGVLPAGRVIGEPTSLMDVFPTV 418
Query: 373 VALAQASLPQGRRFDGVDVSEVLFGRSQ-PGHRVLFHPNSGAAGEFGALQTVRLERYKAF 431
V LA +PQ R DG D+ +L G +Q H L H Q R +K
Sbjct: 419 VRLAGGEVPQDRVIDGQDLLPLLLGTAQHSDHEFLMHYCERFLHAARWHQRDRGTMWKVH 478
Query: 432 YIT-----GGARACDGST------GPELQHKFPLIFNLEDDTAEAVPLERGGAE-YQAVL 479
++T GA AC G + H PL+F+L D +E L + V+
Sbjct: 479 FVTPVFQPEGAGACYGRKVCPCFGEKVVHHDPPLLFDLSRDPSETHILTPASEPVFYQVM 538
Query: 480 PEVRKVLADVLQDIAND--NISSADYTQDPSVTPCCNPYQIACRC 522
V++ + + + ++ + P + PCC P+ + C C
Sbjct: 539 ERVQQAVWEHQRTLSPVPLQLDRLGNIWRPWLQPCCGPFPL-CWC 582
>gi|53831991 steryl-sulfatase precursor [Homo sapiens]
Length = 583
Score = 123 bits (308), Expect = 5e-28
Identities = 100/338 (29%), Positives = 152/338 (44%), Gaps = 27/338 (7%)
Query: 203 LYENLNIVEQPVNLSSLAQKYAEKATQFIQRASTSGRPFLLYVALAHMHVPLPVTQLPAA 262
+ N I++QP++ +L Q+ +A QFIQR + + PFLL ++ H+H L ++ A
Sbjct: 244 MMRNYEIIQQPMSYDNLTQRLTVEAAQFIQRNTET--PFLLVLSYLHVHTALFSSKDFAG 301
Query: 263 PRGRSLYGAGLWEMDSLVGQIKDKVDHT-VKENTFLWFTGDNGPWAQKCELAGSV-GPFT 320
+YG + EMD VGQI + +D + +T ++FT D G ++ G + G
Sbjct: 302 KSQHGVYGDAVEEMDWSVGQILNLLDELRLANDTLIYFTSDQGAHVEEVSSKGEIHGGSN 361
Query: 321 GFWQTRQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSTALLSVLDIFPTVVALAQASL 380
G ++ GG K WEGG RVP + WP + S +DIFPTV LA A L
Sbjct: 362 GIYK---GG---KANNWEGGIRVPGILRWPRVIQAGQKIDEPTSNMDIFPTVAKLAGAPL 415
Query: 381 PQGRRFDGVDVSEVLFGRSQ-PGHRVLFHPNSGAAGEFGALQTVRLERYKAFYITG---- 435
P+ R DG D+ +L G+SQ H LFH + +KAF+ T
Sbjct: 416 PEDRIIDGRDLMPLLEGKSQRSDHEFLFHYCNAYLNAVRWHPQNSTSIWKAFFFTPNFNP 475
Query: 436 -GARACDGS------TGPELQHKFPLIFNLEDDTAEAVPL----ERGGAEYQAVLPEVRK 484
G+ C + H PL+F++ D E PL E E V+ E
Sbjct: 476 VGSNGCFATHVCFCFGSYVTHHDPPLLFDISKDPRERNPLTPASEPRFYEILKVMQEAAD 535
Query: 485 VLADVLQDIANDNISSADYTQDPSVTPCCNPYQIACRC 522
L ++ D S ++ P + CC ++C+C
Sbjct: 536 RHTQTLPEVP-DQFSWNNFLWKPWLQLCCPSTGLSCQC 572
Score = 110 bits (274), Expect = 4e-24
Identities = 60/150 (40%), Positives = 90/150 (60%), Gaps = 12/150 (8%)
Query: 35 KPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTCSPSRASLLTG 94
+PN ++++ADD+G GD G +T T N+D++AS G++ AA+ C+PSRA+ +TG
Sbjct: 26 RPNIILVMADDLGIGDPGCYGNKTIRTPNIDRLASGGVKLTQHLAASPLCTPSRAAFMTG 85
Query: 95 RLGLRNGV-----TRNFAVT-SVGGLPLNETTLAEVLQQAGYVTGIIGKWHLGH--HGS- 145
R +R+G+ T F T S GGLP +E T A++L+ GY T +IGKWHLG H
Sbjct: 86 RYPVRSGMASWSRTGVFLFTASSGGLPTDEITFAKLLKDQGYSTALIGKWHLGMSCHSKT 145
Query: 146 ---YHPNFRGFDYYFGIPYSHDMGCTDTPG 172
+HP GF+Y++GI ++ C G
Sbjct: 146 DFCHHPLHHGFNYFYGISLTNLRDCKPGEG 175
>gi|38569407 arylsulfatase B isoform 2 precursor [Homo sapiens]
Length = 413
Score = 122 bits (307), Expect = 6e-28
Identities = 113/387 (29%), Positives = 172/387 (44%), Gaps = 43/387 (11%)
Query: 28 SGKTRGQKPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTCSPS 87
SG + P+ V +LADD+GW D+G + + + T +LD +A+ G+ +D + C+PS
Sbjct: 37 SGAGASRPPHLVFLLADDLGWNDVGFHGSRIR-TPHLDALAAGGV-LLDNYYTQPLCTPS 94
Query: 88 RASLLTGRLGLRNGVTRNFA-VTSVGGLPLNETTLAEVLQQAGYVTGIIGKWHLG-HHGS 145
R+ LLTGR +R G+ +PL+E L ++L++AGY T ++GKWHLG +
Sbjct: 95 RSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKE 154
Query: 146 YHPNFRGFDYYFGIPYSHDMGCTDTPGYNHPPCPACPQGDGPSRNLQRDCYTDVALPLYE 205
P RGFD YFG + +G D Y+H C + N+ R AL +
Sbjct: 155 CLPTRRGFDTYFG----YLLGSEDY--YSHERCTLID-----ALNVTR-----CALDFRD 198
Query: 206 NLNIVEQPVNLSSLAQKYAEKATQFIQRASTSGRPFLLYVALAHMHVPLPVTQLPAAP-- 263
+ N+ S + ++A I +P LY+AL +H PL V + P
Sbjct: 199 GEEVATGYKNMYS-TNIFTKRAIALITNHPPE-KPLFLYLALQSVHEPLQVPEEYLKPYD 256
Query: 264 ----RGRSLYGAGLWEMDSLVGQIKDKVDHT-VKENTFLWFTGDNGPWAQKCELAGSVGP 318
+ R Y + MD VG + + + + NT F+ DNG LAG
Sbjct: 257 FIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQT----LAGGNN- 311
Query: 319 FTGFWQTRQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSTALLSVLDIFPTVVALAQA 378
W R K + WEGG R P V + L+ + D PT+V LA+
Sbjct: 312 ----WPLRG----RKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARG 363
Query: 379 SLPQGRRFDGVDVSEVLFGRSQPGHRV 405
+ DG DV + + P R+
Sbjct: 364 HTNGTKPLDGFDVWKTI-SEGSPSPRI 389
>gi|38569405 arylsulfatase B isoform 1 precursor [Homo sapiens]
Length = 533
Score = 122 bits (307), Expect = 6e-28
Identities = 113/387 (29%), Positives = 172/387 (44%), Gaps = 43/387 (11%)
Query: 28 SGKTRGQKPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTCSPS 87
SG + P+ V +LADD+GW D+G + + + T +LD +A+ G+ +D + C+PS
Sbjct: 37 SGAGASRPPHLVFLLADDLGWNDVGFHGSRIR-TPHLDALAAGGV-LLDNYYTQPLCTPS 94
Query: 88 RASLLTGRLGLRNGVTRNFA-VTSVGGLPLNETTLAEVLQQAGYVTGIIGKWHLG-HHGS 145
R+ LLTGR +R G+ +PL+E L ++L++AGY T ++GKWHLG +
Sbjct: 95 RSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKE 154
Query: 146 YHPNFRGFDYYFGIPYSHDMGCTDTPGYNHPPCPACPQGDGPSRNLQRDCYTDVALPLYE 205
P RGFD YFG + +G D Y+H C + N+ R AL +
Sbjct: 155 CLPTRRGFDTYFG----YLLGSEDY--YSHERCTLID-----ALNVTR-----CALDFRD 198
Query: 206 NLNIVEQPVNLSSLAQKYAEKATQFIQRASTSGRPFLLYVALAHMHVPLPVTQLPAAP-- 263
+ N+ S + ++A I +P LY+AL +H PL V + P
Sbjct: 199 GEEVATGYKNMYS-TNIFTKRAIALITNHPPE-KPLFLYLALQSVHEPLQVPEEYLKPYD 256
Query: 264 ----RGRSLYGAGLWEMDSLVGQIKDKVDHT-VKENTFLWFTGDNGPWAQKCELAGSVGP 318
+ R Y + MD VG + + + + NT F+ DNG LAG
Sbjct: 257 FIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQT----LAGGNN- 311
Query: 319 FTGFWQTRQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSTALLSVLDIFPTVVALAQA 378
W R K + WEGG R P V + L+ + D PT+V LA+
Sbjct: 312 ----WPLRG----RKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARG 363
Query: 379 SLPQGRRFDGVDVSEVLFGRSQPGHRV 405
+ DG DV + + P R+
Sbjct: 364 HTNGTKPLDGFDVWKTI-SEGSPSPRI 389
>gi|59797060 arylsulfatase family, member I [Homo sapiens]
Length = 569
Score = 119 bits (298), Expect = 7e-27
Identities = 115/389 (29%), Positives = 172/389 (44%), Gaps = 60/389 (15%)
Query: 34 QKPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTCSPSRASLLT 93
Q P+ + IL DD G+ D+G + ++ +T LD++A++G++ +++ C+PSR+ LLT
Sbjct: 45 QPPHIIFILTDDQGYHDVGYHGSDI-ETPTLDRLAAKGVKLENYYIQP-ICTPSRSQLLT 102
Query: 94 GRLGLRNGVTRNFAVTSVGG-LPLNETTLAEVLQQAGYVTGIIGKWHLG-HHGSYHPNFR 151
GR + G+ + LPL++ TL + LQ+AGY T ++GKWHLG + P R
Sbjct: 103 GRYQIHTGLQHSIIRPQQPNCLPLDQVTLPQKLQEAGYSTHMVGKWHLGFYRKECLPTRR 162
Query: 152 GFDYYFGIPYSHDMGCTDTPGYNHPPCPACPQGDGPSRNLQRDCYTDVALPLYENLNIVE 211
GFD + G + Y + C DGP C D L+E N V
Sbjct: 163 GFDTFLGSLTG------NVDYYTYDNC------DGPG-----VCGFD----LHEGEN-VA 200
Query: 212 QPVNLSSLAQKYAEKATQFIQRASTSGRPFLLYVALAHMHVPLPVTQLPAAPR------- 264
++ YA++A+ + S RP LYVA +H PL +PR
Sbjct: 201 WGLSGQYSTMLYAQRASHILASHSPQ-RPLFLYVAFQAVHTPL------QSPREYLYRYR 253
Query: 265 -----GRSLYGAGLWEMDSLVGQIKDKVD-HTVKENTFLWFTGDNGPWAQKCELAGSVGP 318
R Y A + MD V I + + N+ + F+ DNG + GS P
Sbjct: 254 TMGNVARRKYAAMVTCMDEAVRNITWALKRYGFYNNSVIIFSSDNG---GQTFSGGSNWP 310
Query: 319 FTGFWQTRQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSTALLSVLDIFPTVVALAQA 378
G K T WEGG R + P TS AL+ + D +PT+V LA
Sbjct: 311 LRG----------RKGTYWEGGVRGLGFVHSPLLKRKQRTSRALMHITDWYPTLVGLAGG 360
Query: 379 SLPQGRRFDGVDV-SEVLFGRSQPGHRVL 406
+ DG DV + GR+ P +L
Sbjct: 361 TTSAADGLDGYDVWPAISEGRASPRTEIL 389
>gi|4506919 N-sulfoglucosamine sulfohydrolase precursor [Homo
sapiens]
Length = 502
Score = 62.4 bits (150), Expect = 1e-09
Identities = 48/131 (36%), Positives = 65/131 (49%), Gaps = 15/131 (11%)
Query: 27 ISGKTRGQKPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTCSP 86
+ G R + N +++LADD G+ + GA T +LD +A + F + + S+CSP
Sbjct: 14 VLGLCRARPRNALLLLADDGGF-ESGAYNNSAIATPHLDALARRSLLFRNAFTSVSSCSP 72
Query: 87 SRASLLT-------GRLGLRNGVTRNFAVTSVGGLPLNETTLAEVLQQAGYVTGIIGKWH 139
SRASLLT G GL V + V LPL +L QAG TGIIGK H
Sbjct: 73 SRASLLTGLPQHQNGMYGLHQDVHHFNSFDKVRSLPL-------LLSQAGVRTGIIGKKH 125
Query: 140 LGHHGSYHPNF 150
+G Y +F
Sbjct: 126 VGPETVYPFDF 136
>gi|4557659 iduronate-2-sulfatase isoform a precursor [Homo sapiens]
Length = 550
Score = 62.0 bits (149), Expect = 1e-09
Identities = 89/424 (20%), Positives = 153/424 (36%), Gaps = 121/424 (28%)
Query: 37 NFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTCSPSRASLLTGRL 96
N ++I+ DD+ LG + + N+D++AS + F + A + C+PSR S LTGR
Sbjct: 38 NVLLIIVDDLR-PSLGCYGDKLVRSPNIDQLASHSLLFQNAFAQQAVCAPSRVSFLTGR- 95
Query: 97 GLRNGVTRNFAVTSVGGLPL-NETTLAEVLQQAGYVTGIIGKWHLGHHGSYHPNFRGFDY 155
R TR + S + N +T+ + ++ GYVT +GK +HP ++
Sbjct: 96 --RPDTTRLYDFNSYWRVHAGNFSTIPQYFKENGYVTMSVGK-------VFHPGISS-NH 145
Query: 156 YFGIPYSHDMGCTDTPGYNHPPCPACPQGDGPSRNLQRDCYTDVALPLYENLNIVEQPVN 215
PYS + C DG + + ++ P+ ++++ P
Sbjct: 146 TDDSPYSWSFPPYHPSSEKYENTKTCRGPDG-------ELHANLLCPV----DVLDVPEG 194
Query: 216 LSSLAQKYAEKATQFIQRASTSGRPFLLYVALAHMHVPL----------PVTQLPAAP-- 263
Q E+A Q +++ TS PF L V H+P P+ + AP
Sbjct: 195 TLPDKQS-TEQAIQLLEKMKTSASPFFLAVGYHKPHIPFRYPKEFQKLYPLENITLAPDP 253
Query: 264 -----------------------------------------RGRSLYGAGLWEMDSLVGQ 282
+ R Y A + +D+ VG+
Sbjct: 254 EVPDGLPPVAYNPWMDIRQREDVQALNISVPYGPIPVDFQRKIRQSYFASVSYLDTQVGR 313
Query: 283 IKDKVDH-TVKENTFLWFTGDNGPWAQKCELAGSVGPFTGFWQTRQGGSPAKQTTWEGGH 341
+ +D + +T + FT D+G W + G AK + ++
Sbjct: 314 LLSALDDLQLANSTIIAFTSDHG------------------WALGEHGEWAKYSNFDVAT 355
Query: 342 RVPALAYWPGRV---------------PVNVTSTA---------LLSVLDIFPTVVALAQ 377
VP + Y PGR P + S L+ ++ +FPT+ LA
Sbjct: 356 HVPLIFYVPGRTASLPEAGEKLFPYLDPFDSASQLMEPGRQSMDLVELVSLFPTLAGLAG 415
Query: 378 ASLP 381
+P
Sbjct: 416 LQVP 419
>gi|5360208 iduronate-2-sulfatase isoform b precursor [Homo sapiens]
Length = 343
Score = 58.9 bits (141), Expect = 1e-08
Identities = 55/218 (25%), Positives = 94/218 (43%), Gaps = 25/218 (11%)
Query: 37 NFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTCSPSRASLLTGRL 96
N ++I+ DD+ LG + + N+D++AS + F + A + C+PSR S LTGR
Sbjct: 38 NVLLIIVDDLR-PSLGCYGDKLVRSPNIDQLASHSLLFQNAFAQQAVCAPSRVSFLTGR- 95
Query: 97 GLRNGVTRNFAVTSVGGLPL-NETTLAEVLQQAGYVTGIIGKWHLGHHGSYHPNFRGFDY 155
R TR + S + N +T+ + ++ GYVT +GK +HP ++
Sbjct: 96 --RPDTTRLYDFNSYWRVHAGNFSTIPQYFKENGYVTMSVGK-------VFHPGISS-NH 145
Query: 156 YFGIPYSHDMGCTDTPGYNHPPCPACPQGDGPSRNLQRDCYTDVALPLYENLNIVEQPVN 215
PYS + C DG + + ++ P+ ++++ P
Sbjct: 146 TDDSPYSWSFPPYHPSSEKYENTKTCRGPDG-------ELHANLLCPV----DVLDVPEG 194
Query: 216 LSSLAQKYAEKATQFIQRASTSGRPFLLYVALAHMHVP 253
Q E+A Q +++ TS PF L V H+P
Sbjct: 195 TLPDKQS-TEQAIQLLEKMKTSASPFFLAVGYHKPHIP 231
>gi|4504061 glucosamine (N-acetyl)-6-sulfatase precursor [Homo
sapiens]
Length = 552
Score = 54.3 bits (129), Expect = 3e-07
Identities = 96/400 (24%), Positives = 170/400 (42%), Gaps = 58/400 (14%)
Query: 25 FCISGKTRGQKPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTC 84
F ++ TR +PN V++L DD LG K A + +M GM F + ++ C
Sbjct: 38 FGVAAGTR--RPNVVLLLTDDQD-EVLGGMTPLKKTKALIGEM---GMTFSSAYVPSALC 91
Query: 85 SPSRASLLTGRLG-----LRNGVTRNFAVTSVGGLPLNETTLAEVLQQAGYVTGIIGKWH 139
PSRAS+LTG+ + N + N + S + T A + GY T GK+
Sbjct: 92 CPSRASILTGKYPHNHHVVNNTLEGNCSSKSWQKIQEPNTFPAILRSMCGYQTFFAGKY- 150
Query: 140 LGHHGSYHPNFRGFDYY-FGIPYSHDMGCTDTPGYNHPPC---PACPQGDGPSRNLQRDC 195
L +G+ P+ G ++ G Y + + ++ YN+ A G+ S + D
Sbjct: 151 LNEYGA--PDAGGLEHVPLGWSYWYALE-KNSKYYNYTLSINGKARKHGENYSVDYLTDV 207
Query: 196 YTDVALPLYENLNIVEQ---------PVNLSSLAQKYAEKATQFIQRASTSGRPFLLYVA 246
+V+L + + E P + + A +Y +KA Q + + + F ++
Sbjct: 208 LANVSLDFLDYKSNFEPFFMMIATPAPHSPWTAAPQY-QKAFQNV--FAPRNKNFNIHGT 264
Query: 247 LAHMHV-----PLPVTQLPAAPRGRSLYGAGLWEMDSLVGQIKDKVDHTVK-ENTFLWFT 300
H + P+ + + L +D LV ++ +++ T + NT++++T
Sbjct: 265 NKHWLIRQAKTPMTNSSIQFLDNAFRKRWQTLLSVDDLVEKLVKRLEFTGELNNTYIFYT 324
Query: 301 GDNGPWAQKCELAGSVGPFTGFWQTRQGGSPA-KQTTWEGGHRVPALAYWPGRVPVNVTS 359
DNG + T Q P K+ +E +VP L PG P N TS
Sbjct: 325 SDNG------------------YHTGQFSLPIDKRQLYEFDIKVPLLVRGPGIKP-NQTS 365
Query: 360 TALLSVLDIFPTVVALAQASLPQGRRFDGVDVSEVLFGRS 399
L++ +D+ PT++ +A L + + DG+ + +L G S
Sbjct: 366 KMLVANIDLGPTILDIAGYDLNK-TQMDGMSLLPILRGAS 404
>gi|240255483 sulfatase 2 isoform a precursor [Homo sapiens]
Length = 870
Score = 48.9 bits (115), Expect = 1e-05
Identities = 36/119 (30%), Positives = 57/119 (47%), Gaps = 6/119 (5%)
Query: 32 RGQKPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTCSPSRASL 91
R +PN +++L DD +LG+ K +++ G F++ C PSR+S+
Sbjct: 40 RNIRPNIILVLTDDQDV-ELGSMQVMNKTRRIMEQ---GGAHFINAFVTTPMCCPSRSSI 95
Query: 92 LTGR-LGLRNGVTRNFAVTSVGGLPLNET-TLAEVLQQAGYVTGIIGKWHLGHHGSYHP 148
LTG+ + N T N +S +E+ T A L GY T GK+ ++GSY P
Sbjct: 96 LTGKYVHNHNTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVP 154
>gi|240255478 sulfatase 2 isoform b precursor [Homo sapiens]
Length = 867
Score = 48.9 bits (115), Expect = 1e-05
Identities = 36/119 (30%), Positives = 57/119 (47%), Gaps = 6/119 (5%)
Query: 32 RGQKPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTCSPSRASL 91
R +PN +++L DD +LG+ K +++ G F++ C PSR+S+
Sbjct: 40 RNIRPNIILVLTDDQDV-ELGSMQVMNKTRRIMEQ---GGAHFINAFVTTPMCCPSRSSI 95
Query: 92 LTGR-LGLRNGVTRNFAVTSVGGLPLNET-TLAEVLQQAGYVTGIIGKWHLGHHGSYHP 148
LTG+ + N T N +S +E+ T A L GY T GK+ ++GSY P
Sbjct: 96 LTGKYVHNHNTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVP 154
>gi|29789100 sulfatase 2 isoform a precursor [Homo sapiens]
Length = 870
Score = 48.9 bits (115), Expect = 1e-05
Identities = 36/119 (30%), Positives = 57/119 (47%), Gaps = 6/119 (5%)
Query: 32 RGQKPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTCSPSRASL 91
R +PN +++L DD +LG+ K +++ G F++ C PSR+S+
Sbjct: 40 RNIRPNIILVLTDDQDV-ELGSMQVMNKTRRIMEQ---GGAHFINAFVTTPMCCPSRSSI 95
Query: 92 LTGR-LGLRNGVTRNFAVTSVGGLPLNET-TLAEVLQQAGYVTGIIGKWHLGHHGSYHP 148
LTG+ + N T N +S +E+ T A L GY T GK+ ++GSY P
Sbjct: 96 LTGKYVHNHNTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVP 154
>gi|189571643 sulfatase 1 [Homo sapiens]
Length = 871
Score = 47.8 bits (112), Expect = 3e-05
Identities = 38/124 (30%), Positives = 59/124 (47%), Gaps = 6/124 (4%)
Query: 27 ISGKTRGQKPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTCSP 86
I + + +PN +++L DD +LG+ K T + M G F++ C P
Sbjct: 34 IQQERKNIRPNIILVLTDDQDV-ELGSLQVMNK-TRKI--MEHGGATFINAFVTTPMCCP 89
Query: 87 SRASLLTGR-LGLRNGVTRNFAVTSVGGLPLNE-TTLAEVLQQAGYVTGIIGKWHLGHHG 144
SR+S+LTG+ + N T N +S ++E T A L GY T GK+ ++G
Sbjct: 90 SRSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKYLNEYNG 149
Query: 145 SYHP 148
SY P
Sbjct: 150 SYIP 153
>gi|189571641 sulfatase 1 [Homo sapiens]
Length = 871
Score = 47.8 bits (112), Expect = 3e-05
Identities = 38/124 (30%), Positives = 59/124 (47%), Gaps = 6/124 (4%)
Query: 27 ISGKTRGQKPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTCSP 86
I + + +PN +++L DD +LG+ K T + M G F++ C P
Sbjct: 34 IQQERKNIRPNIILVLTDDQDV-ELGSLQVMNK-TRKI--MEHGGATFINAFVTTPMCCP 89
Query: 87 SRASLLTGR-LGLRNGVTRNFAVTSVGGLPLNE-TTLAEVLQQAGYVTGIIGKWHLGHHG 144
SR+S+LTG+ + N T N +S ++E T A L GY T GK+ ++G
Sbjct: 90 SRSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKYLNEYNG 149
Query: 145 SYHP 148
SY P
Sbjct: 150 SYIP 153
>gi|189571638 sulfatase 1 [Homo sapiens]
Length = 871
Score = 47.8 bits (112), Expect = 3e-05
Identities = 38/124 (30%), Positives = 59/124 (47%), Gaps = 6/124 (4%)
Query: 27 ISGKTRGQKPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTCSP 86
I + + +PN +++L DD +LG+ K T + M G F++ C P
Sbjct: 34 IQQERKNIRPNIILVLTDDQDV-ELGSLQVMNK-TRKI--MEHGGATFINAFVTTPMCCP 89
Query: 87 SRASLLTGR-LGLRNGVTRNFAVTSVGGLPLNE-TTLAEVLQQAGYVTGIIGKWHLGHHG 144
SR+S+LTG+ + N T N +S ++E T A L GY T GK+ ++G
Sbjct: 90 SRSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKYLNEYNG 149
Query: 145 SYHP 148
SY P
Sbjct: 150 SYIP 153
>gi|189571636 sulfatase 1 [Homo sapiens]
Length = 871
Score = 47.8 bits (112), Expect = 3e-05
Identities = 38/124 (30%), Positives = 59/124 (47%), Gaps = 6/124 (4%)
Query: 27 ISGKTRGQKPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTCSP 86
I + + +PN +++L DD +LG+ K T + M G F++ C P
Sbjct: 34 IQQERKNIRPNIILVLTDDQDV-ELGSLQVMNK-TRKI--MEHGGATFINAFVTTPMCCP 89
Query: 87 SRASLLTGR-LGLRNGVTRNFAVTSVGGLPLNE-TTLAEVLQQAGYVTGIIGKWHLGHHG 144
SR+S+LTG+ + N T N +S ++E T A L GY T GK+ ++G
Sbjct: 90 SRSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKYLNEYNG 149
Query: 145 SYHP 148
SY P
Sbjct: 150 SYIP 153
>gi|169217295 PREDICTED: similar to iduronate 2-sulfatase (Hunter
syndrome) [Homo sapiens]
Length = 142
Score = 45.4 bits (106), Expect = 1e-04
Identities = 31/95 (32%), Positives = 50/95 (52%), Gaps = 6/95 (6%)
Query: 63 NLDKMASEGMRFVDFHAAASTCSPSRASLLTGRLGLRNGVTRNFAVTSVGGLPL-NETTL 121
N+D++AS + F + A + C+PSR S LTGR R TR + S + N +T+
Sbjct: 26 NIDQLASHSLLFQNAFAQQAVCAPSRVSFLTGR---RPDTTRLYDFNSYWRVHAGNFSTI 82
Query: 122 AEVLQQAGYVTGIIGKWHLGHHGSYHPNFRGFDYY 156
+ ++ GYVT +GK + H G+ GF ++
Sbjct: 83 PQYFKENGYVTMSVGK--VFHPGTAPRPESGFSWF 115
>gi|39930577 arylsulfatase K [Homo sapiens]
Length = 536
Score = 38.9 bits (89), Expect = 0.012
Identities = 29/110 (26%), Positives = 50/110 (45%), Gaps = 7/110 (6%)
Query: 36 PNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTCSPSRASLLTGR 95
PN V++++D ++ ++ M + G F++ + + C PSRA++ +G
Sbjct: 32 PNVVLVVSDSFDGRLTFHPGSQVVKLPFINFMKTRGTSFLNAYTNSPICCPSRAAMWSGL 91
Query: 96 LGLRNGVTRNFAVTSVGGLPLNETTLAEVLQQAGYVTGIIGK--WHLGHH 143
NF GL N TT +V+++ GY T GK + GHH
Sbjct: 92 FTHLTESWNNFK-----GLDPNYTTWMDVMERHGYRTQKFGKLDYTSGHH 136
Score = 32.3 bits (72), Expect = 1.1
Identities = 30/118 (25%), Positives = 55/118 (46%), Gaps = 20/118 (16%)
Query: 266 RSLYGAGLWEMDSLVGQIKDKVDHT-VKENTFLWFTGDNGPWAQKCELAGSVGPFTGFWQ 324
R+ Y A E D+++G+I + + + T + ++ D+G ELA F
Sbjct: 276 RAFYYAMCAETDAMLGEIILALHQLDLLQKTIVIYSSDHG------ELAMEHRQFY---- 325
Query: 325 TRQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSTALLSVLDIFPTVVALAQASLPQ 382
K + +E VP L PG + + + ++S++DI+PT++ +A LPQ
Sbjct: 326 --------KMSMYEASAHVPLLMMGPG-IKAGLQVSNVVSLVDIYPTMLDIAGIPLPQ 374
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.436
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,581,556
Number of Sequences: 37866
Number of extensions: 1039425
Number of successful extensions: 2527
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 2393
Number of HSP's gapped (non-prelim): 48
length of query: 525
length of database: 18,247,518
effective HSP length: 107
effective length of query: 418
effective length of database: 14,195,856
effective search space: 5933867808
effective search space used: 5933867808
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.