Guide to the Human Genome
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Search of human proteins with 4507879

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4507879 voltage-dependent anion channel 1 [Homo sapiens]
         (283 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4507879 voltage-dependent anion channel 1 [Homo sapiens]           574   e-164
gi|42476281 voltage-dependent anion channel 2 [Homo sapiens]          459   e-129
gi|113412878 PREDICTED: similar to voltage-dependent anion chann...   454   e-128
gi|169164151 PREDICTED: similar to voltage-dependent anion chann...   452   e-127
gi|169163967 PREDICTED: similar to voltage-dependent anion chann...   450   e-127
gi|25188179 voltage-dependent anion channel 3 isoform b [Homo sa...   409   e-114
gi|208879465 voltage-dependent anion channel 3 isoform a [Homo s...   404   e-113
gi|34452732 phosphatidylinositol-3,4,5-trisphosphate-dependent R...    29   5.3  
gi|6912630 interferon-induced protein with tetratricopeptide rep...    29   5.3  
gi|58331272 zinc finger, CCHC domain containing 6 [Homo sapiens]       28   9.1  
gi|31621303 sideroflexin 3 [Homo sapiens]                              28   9.1  

>gi|4507879 voltage-dependent anion channel 1 [Homo sapiens]
          Length = 283

 Score =  574 bits (1479), Expect = e-164
 Identities = 283/283 (100%), Positives = 283/283 (100%)

Query: 1   MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVTGSLET 60
           MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVTGSLET
Sbjct: 1   MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVTGSLET 60

Query: 61  KYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKR 120
           KYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKR
Sbjct: 61  KYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKR 120

Query: 121 EHINLGCDMDFDIAGPSIRGALVLGYEGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQL 180
           EHINLGCDMDFDIAGPSIRGALVLGYEGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQL
Sbjct: 121 EHINLGCDMDFDIAGPSIRGALVLGYEGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQL 180

Query: 181 HTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQIDPDACFSAKVNNS 240
           HTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQIDPDACFSAKVNNS
Sbjct: 181 HTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQIDPDACFSAKVNNS 240

Query: 241 SLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA 283
           SLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA
Sbjct: 241 SLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA 283


>gi|42476281 voltage-dependent anion channel 2 [Homo sapiens]
          Length = 294

 Score =  459 bits (1180), Expect = e-129
 Identities = 211/283 (74%), Positives = 258/283 (91%)

Query: 1   MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVTGSLET 60
           M +PP+YADLGK+ARD+F KG+GFGL+KLD+KTKS +G+EF++SGS+NT+T KVTG+LET
Sbjct: 12  MCIPPSYADLGKAARDIFNKGFGFGLVKLDVKTKSCSGVEFSTSGSSNTDTGKVTGTLET 71

Query: 61  KYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKR 120
           KY+W EYGLTFTEKWNTDNTLGTEI +EDQ+ +GLKLTFD++FSPNTGKK+ KIK+ YKR
Sbjct: 72  KYKWCEYGLTFTEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFSPNTGKKSGKIKSSYKR 131

Query: 121 EHINLGCDMDFDIAGPSIRGALVLGYEGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQL 180
           E INLGCD+DFD AGP+I G+ V GYEGWLAGYQM F++AKS++T++NFAVGY+T +FQL
Sbjct: 132 ECINLGCDVDFDFAGPAIHGSAVFGYEGWLAGYQMTFDSAKSKLTRNNFAVGYRTGDFQL 191

Query: 181 HTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQIDPDACFSAKVNNS 240
           HTNVNDGTEFGGSIYQKV + L+T+VNLAWT+G + TRFGIAAKYQ+DP A  SAKVNNS
Sbjct: 192 HTNVNDGTEFGGSIYQKVCEDLDTSVNLAWTSGTNCTRFGIAAKYQLDPTASISAKVNNS 251

Query: 241 SLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA 283
           SLIG+GYTQTL+PG+KLTLSAL+DGK++NAGGHK+GL LE +A
Sbjct: 252 SLIGVGYTQTLRPGVKLTLSALVDGKSINAGGHKVGLALELEA 294


>gi|113412878 PREDICTED: similar to voltage-dependent anion channel
           2 [Homo sapiens]
          Length = 293

 Score =  454 bits (1168), Expect = e-128
 Identities = 211/283 (74%), Positives = 258/283 (91%), Gaps = 1/283 (0%)

Query: 1   MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVTGSLET 60
           M +PP+YADLGK+ARD+F KG+GFGL+KLD+KTKS +G+EF++SGS+NT+T KVTG+LET
Sbjct: 12  MCIPPSYADLGKAARDIFNKGFGFGLVKLDVKTKSCSGVEFSTSGSSNTDTGKVTGTLET 71

Query: 61  KYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKR 120
           KY+W EYGLTFTEKWNTDNTLGTEI +EDQ+ +GLKLTFD++FSPNTGKK+ KIK+ YKR
Sbjct: 72  KYKWCEYGLTFTEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFSPNTGKKSGKIKS-YKR 130

Query: 121 EHINLGCDMDFDIAGPSIRGALVLGYEGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQL 180
           E INLGCD+DFD AGP+I G+ V GYEGWLAGYQM F++AKS++T++NFAVGY+T +FQL
Sbjct: 131 ECINLGCDVDFDFAGPAIHGSAVFGYEGWLAGYQMTFDSAKSKLTRNNFAVGYRTGDFQL 190

Query: 181 HTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQIDPDACFSAKVNNS 240
           HTNVNDGTEFGGSIYQKV + L+T+VNLAWT+G + TRFGIAAKYQ+DP A  SAKVNNS
Sbjct: 191 HTNVNDGTEFGGSIYQKVCEDLDTSVNLAWTSGTNCTRFGIAAKYQLDPTASISAKVNNS 250

Query: 241 SLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA 283
           SLIG+GYTQTL+PG+KLTLSAL+DGK++NAGGHK+GL LE +A
Sbjct: 251 SLIGVGYTQTLRPGVKLTLSALVDGKSINAGGHKVGLALELEA 293


>gi|169164151 PREDICTED: similar to voltage-dependent anion channel
           2 [Homo sapiens]
          Length = 293

 Score =  452 bits (1162), Expect = e-127
 Identities = 210/283 (74%), Positives = 257/283 (90%), Gaps = 1/283 (0%)

Query: 1   MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVTGSLET 60
           M +PP+YADLGK+ARD+F KG+GFGL+KLD+KTKS +G+EF++SGS+NT+T KVTG+LET
Sbjct: 12  MCIPPSYADLGKAARDIFNKGFGFGLVKLDVKTKSCSGVEFSTSGSSNTDTGKVTGTLET 71

Query: 61  KYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKR 120
           KY+W EYGLT TEKWNTDNTLGTEI +EDQ+ +GLKLTFD++FSPNTGKK+ KIK+ YKR
Sbjct: 72  KYKWCEYGLTITEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFSPNTGKKSGKIKS-YKR 130

Query: 121 EHINLGCDMDFDIAGPSIRGALVLGYEGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQL 180
           E INLGCD+DFD AGP+I G+ V GYEGWLAGYQM F++AKS++T++NFAVGY+T +FQL
Sbjct: 131 ECINLGCDVDFDFAGPAIHGSAVFGYEGWLAGYQMTFDSAKSKLTRNNFAVGYRTGDFQL 190

Query: 181 HTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQIDPDACFSAKVNNS 240
           HTNVNDGTEFGGSIYQKV + L+T+VNLAWT+G + TRFGIAAKYQ+DP A  SAKVNNS
Sbjct: 191 HTNVNDGTEFGGSIYQKVCEDLDTSVNLAWTSGTNCTRFGIAAKYQLDPTASISAKVNNS 250

Query: 241 SLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA 283
           SLIG+GYTQTL+PG+KLTLSAL+DGK++NAGGHK+GL LE +A
Sbjct: 251 SLIGVGYTQTLRPGVKLTLSALVDGKSINAGGHKVGLALELEA 293


>gi|169163967 PREDICTED: similar to voltage-dependent anion channel
           2 [Homo sapiens]
          Length = 293

 Score =  450 bits (1158), Expect = e-127
 Identities = 210/283 (74%), Positives = 256/283 (90%), Gaps = 1/283 (0%)

Query: 1   MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVTGSLET 60
           M +PP+YADLGK+ARD+F KG+GFGL+KLD+KTKS +G+EF++SGS+NT+T KVTG+LET
Sbjct: 12  MCIPPSYADLGKAARDIFNKGFGFGLVKLDVKTKSCSGVEFSTSGSSNTDTGKVTGTLET 71

Query: 61  KYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKR 120
           KY+W EYGLT TEKWNTDNTLGTEI +EDQ+ +GLKLTFD++FSPNTGKK+ KIK+ YKR
Sbjct: 72  KYKWCEYGLTITEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFSPNTGKKSGKIKS-YKR 130

Query: 121 EHINLGCDMDFDIAGPSIRGALVLGYEGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQL 180
           E INLGCD+DFD AGP+I G+ V GYEGWLAGYQM F++AKS++T++NFAVGY+T +FQL
Sbjct: 131 ECINLGCDVDFDFAGPAIHGSAVFGYEGWLAGYQMTFDSAKSKLTRNNFAVGYRTGDFQL 190

Query: 181 HTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQIDPDACFSAKVNNS 240
           HTNVNDGTEFGGSIYQKV + L+T+VNLAWT+G + TRFGIAAKYQ DP A  SAKVNNS
Sbjct: 191 HTNVNDGTEFGGSIYQKVCEDLDTSVNLAWTSGTNCTRFGIAAKYQSDPTASISAKVNNS 250

Query: 241 SLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA 283
           SLIG+GYTQTL+PG+KLTLSAL+DGK++NAGGHK+GL LE +A
Sbjct: 251 SLIGVGYTQTLRPGVKLTLSALVDGKSINAGGHKVGLALELEA 293


>gi|25188179 voltage-dependent anion channel 3 isoform b [Homo
           sapiens]
          Length = 283

 Score =  409 bits (1050), Expect = e-114
 Identities = 191/283 (67%), Positives = 242/283 (85%)

Query: 1   MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVTGSLET 60
           M   PTY DLGK+A+DVF KGYGFG++K+DLKTKS +G+EF++SG A T+T K +G+LET
Sbjct: 1   MCNTPTYCDLGKAAKDVFNKGYGFGMVKIDLKTKSCSGVEFSTSGHAYTDTGKASGNLET 60

Query: 61  KYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKR 120
           KY+   YGLTFT+KWNTDNTLGTEI+ E++LA GLKLT D+ F PNTGKK+ K+K  YKR
Sbjct: 61  KYKVCNYGLTFTQKWNTDNTLGTEISWENKLAEGLKLTLDTIFVPNTGKKSGKLKASYKR 120

Query: 121 EHINLGCDMDFDIAGPSIRGALVLGYEGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQL 180
           +  ++G ++D D +GP+I G  VL +EGWLAGYQM+F+TAKS+++Q+NFA+GYK  +FQL
Sbjct: 121 DCFSVGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQL 180

Query: 181 HTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQIDPDACFSAKVNNS 240
           HT+VNDGTEFGGSIYQKVN+K+ET++NLAWTAG++NTRFGIAAKY +D     SAKVNN+
Sbjct: 181 HTHVNDGTEFGGSIYQKVNEKIETSINLAWTAGSNNTRFGIAAKYMLDCRTSLSAKVNNA 240

Query: 241 SLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA 283
           SLIGLGYTQTL+PG+KLTLSAL+DGKN +AGGHK+GLG E +A
Sbjct: 241 SLIGLGYTQTLRPGVKLTLSALIDGKNFSAGGHKVGLGFELEA 283


>gi|208879465 voltage-dependent anion channel 3 isoform a [Homo
           sapiens]
          Length = 284

 Score =  404 bits (1039), Expect = e-113
 Identities = 191/284 (67%), Positives = 242/284 (85%), Gaps = 1/284 (0%)

Query: 1   MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENG-LEFTSSGSANTETTKVTGSLE 59
           M   PTY DLGK+A+DVF KGYGFG++K+DLKTKS +G +EF++SG A T+T K +G+LE
Sbjct: 1   MCNTPTYCDLGKAAKDVFNKGYGFGMVKIDLKTKSCSGVMEFSTSGHAYTDTGKASGNLE 60

Query: 60  TKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYK 119
           TKY+   YGLTFT+KWNTDNTLGTEI+ E++LA GLKLT D+ F PNTGKK+ K+K  YK
Sbjct: 61  TKYKVCNYGLTFTQKWNTDNTLGTEISWENKLAEGLKLTLDTIFVPNTGKKSGKLKASYK 120

Query: 120 REHINLGCDMDFDIAGPSIRGALVLGYEGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQ 179
           R+  ++G ++D D +GP+I G  VL +EGWLAGYQM+F+TAKS+++Q+NFA+GYK  +FQ
Sbjct: 121 RDCFSVGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQ 180

Query: 180 LHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQIDPDACFSAKVNN 239
           LHT+VNDGTEFGGSIYQKVN+K+ET++NLAWTAG++NTRFGIAAKY +D     SAKVNN
Sbjct: 181 LHTHVNDGTEFGGSIYQKVNEKIETSINLAWTAGSNNTRFGIAAKYMLDCRTSLSAKVNN 240

Query: 240 SSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA 283
           +SLIGLGYTQTL+PG+KLTLSAL+DGKN +AGGHK+GLG E +A
Sbjct: 241 ASLIGLGYTQTLRPGVKLTLSALIDGKNFSAGGHKVGLGFELEA 284


>gi|34452732 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac
           exchange factor 1 [Homo sapiens]
          Length = 1659

 Score = 28.9 bits (63), Expect = 5.3
 Identities = 18/56 (32%), Positives = 23/56 (41%)

Query: 25  GLIKLDLKTKSENGLEFTSSGSANTETTKVTGSLETKYRWTEYGLTFTEKWNTDNT 80
           G  K   +TKS NG  +   G  NTE  +V    +    +   G T T  W   NT
Sbjct: 309 GSKKSTKRTKSINGSLYIFRGRINTEVMEVENVEDGTADYHSNGYTVTNGWKIHNT 364


>gi|6912630 interferon-induced protein with tetratricopeptide
           repeats 5 [Homo sapiens]
          Length = 482

 Score = 28.9 bits (63), Expect = 5.3
 Identities = 27/89 (30%), Positives = 38/89 (42%), Gaps = 5/89 (5%)

Query: 189 EFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQIDPDACFSAKVNNSSLIGLGYT 248
           +FGG  YQK     E A+ +       N  + I   Y++D D+     V + SL  L   
Sbjct: 150 KFGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITV-YRLD-DSDREGSVKSFSLGPLRKA 207

Query: 249 QTLKPG---IKLTLSALLDGKNVNAGGHK 274
            TL P    IK+ L+  L   +  A G K
Sbjct: 208 VTLNPDNSYIKVFLALKLQDVHAEAEGEK 236


>gi|58331272 zinc finger, CCHC domain containing 6 [Homo sapiens]
          Length = 1495

 Score = 28.1 bits (61), Expect = 9.1
 Identities = 11/24 (45%), Positives = 15/24 (62%)

Query: 100 DSSFSPNTGKKNAKIKTGYKREHI 123
           D  + P TG+KN K K G K +H+
Sbjct: 739 DKVYHPETGRKNEKEKVGRKGKHL 762


>gi|31621303 sideroflexin 3 [Homo sapiens]
          Length = 325

 Score = 28.1 bits (61), Expect = 9.1
 Identities = 19/54 (35%), Positives = 29/54 (53%), Gaps = 4/54 (7%)

Query: 88  EDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINL---GCDMDFDIAGPSI 138
           EDQL R  K  +DS+F P+TG+K   I     +  +N+   GC + F    P++
Sbjct: 68  EDQLWRA-KYVYDSAFHPDTGEKVVLIGRMSAQVPMNMTITGCMLTFYRKTPTV 120


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.132    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,824,662
Number of Sequences: 37866
Number of extensions: 372315
Number of successful extensions: 523
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 510
Number of HSP's gapped (non-prelim): 11
length of query: 283
length of database: 18,247,518
effective HSP length: 101
effective length of query: 182
effective length of database: 14,423,052
effective search space: 2624995464
effective search space used: 2624995464
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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