Search of human proteins with 4507725

Search of human proteins with 4507725

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4507725 transthyretin precursor [Homo sapiens]
         (147 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4507725 transthyretin precursor [Homo sapiens]                     297   2e-81
gi|195546926 LIM domain binding 2 isoform b [Homo sapiens]             28   2.1  
gi|4504971 LIM domain binding 2 isoform a [Homo sapiens]               28   2.1  
gi|42794620 Huntingtin interacting protein E [Homo sapiens]            28   3.6  
gi|154350241 brefeldin A-inhibited guanine nucleotide-exchange p...    27   6.1  
gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]                 27   6.1  
gi|46409558 beta-defensin 32 precursor [Homo sapiens]                  27   8.0  
gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]            27   8.0  
gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens]     27   8.0  

>gi|4507725 transthyretin precursor [Homo sapiens]
          Length = 147

 Score =  297 bits (761), Expect = 2e-81
 Identities = 147/147 (100%), Positives = 147/147 (100%)

Query: 1   MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDT 60
           MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDT
Sbjct: 1   MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDT 60

Query: 61  WEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDS 120
           WEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDS
Sbjct: 61  WEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDS 120

Query: 121 GPRRYTIAALLSPYSYSTTAVVTNPKE 147
           GPRRYTIAALLSPYSYSTTAVVTNPKE
Sbjct: 121 GPRRYTIAALLSPYSYSTTAVVTNPKE 147


>gi|195546926 LIM domain binding 2 isoform b [Homo sapiens]
          Length = 331

 Score = 28.5 bits (62), Expect = 2.1
 Identities = 15/50 (30%), Positives = 23/50 (46%), Gaps = 1/50 (2%)

Query: 90  KVEIDTKSYWKALGISPFHEHAEVVFT-ANDSGPRRYTIAALLSPYSYST 138
           + E     +W A     F + A +  +   + GP+RYTI   L P  +ST
Sbjct: 42  RTEDSDNLWWDAFATEFFEDDATLTLSFCLEDGPKRYTIGRTLIPRYFST 91


>gi|4504971 LIM domain binding 2 isoform a [Homo sapiens]
          Length = 373

 Score = 28.5 bits (62), Expect = 2.1
 Identities = 15/50 (30%), Positives = 23/50 (46%), Gaps = 1/50 (2%)

Query: 90  KVEIDTKSYWKALGISPFHEHAEVVFT-ANDSGPRRYTIAALLSPYSYST 138
           + E     +W A     F + A +  +   + GP+RYTI   L P  +ST
Sbjct: 42  RTEDSDNLWWDAFATEFFEDDATLTLSFCLEDGPKRYTIGRTLIPRYFST 91


>gi|42794620 Huntingtin interacting protein E [Homo sapiens]
          Length = 458

 Score = 27.7 bits (60), Expect = 3.6
 Identities = 21/72 (29%), Positives = 34/72 (47%), Gaps = 12/72 (16%)

Query: 54  RKAADDTWEPFASGKTSESGEL--HGLTTEEEFVEGIYKVEIDTKS----------YWKA 101
           R A +   E    GK  ++ +L  H L  + +FV+ + +  I ++           Y +A
Sbjct: 107 RAALNQALEMKRQGKREKAQKLFMHALKMDPDFVDALTEFGIFSEEDKDIIQADYLYTRA 166

Query: 102 LGISPFHEHAEV 113
           L ISP+HE A V
Sbjct: 167 LTISPYHEKALV 178


>gi|154350241 brefeldin A-inhibited guanine nucleotide-exchange
           protein 3 [Homo sapiens]
          Length = 2177

 Score = 26.9 bits (58), Expect = 6.1
 Identities = 19/81 (23%), Positives = 36/81 (44%), Gaps = 2/81 (2%)

Query: 17  VSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELH 76
           + EAG  G+ E     ++ +L  + G  +  +   +   AA ++  PFA  +  +   + 
Sbjct: 799 LGEAGYWGSPEDNSLPLITMLTDIDGLESSAIGGQLMASAATES--PFAQSRRIDDSTVA 856

Query: 77  GLTTEEEFVEGIYKVEIDTKS 97
           G+      + G +K  IDT S
Sbjct: 857 GVAFARYILVGCWKNLIDTLS 877


>gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]
          Length = 1796

 Score = 26.9 bits (58), Expect = 6.1
 Identities = 21/82 (25%), Positives = 39/82 (47%), Gaps = 10/82 (12%)

Query: 43  SPAINVAV-HVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEG--IYKVEIDTKSYW 99
           SP  N+ + +V   +A  TW+P        S +++G        +G  I +VE+D  + +
Sbjct: 536 SPPRNLRISNVGSNSARLTWDP-------TSRQINGYRIVYNNADGTEINEVEVDPITTF 588

Query: 100 KALGISPFHEHAEVVFTANDSG 121
              G++P  E+   +F+  D G
Sbjct: 589 PLKGLTPLTEYTIAIFSIYDEG 610


>gi|46409558 beta-defensin 32 precursor [Homo sapiens]
          Length = 95

 Score = 26.6 bits (57), Expect = 8.0
 Identities = 12/26 (46%), Positives = 16/26 (61%)

Query: 5  RLLLLCLAGLVFVSEAGPTGTGESKC 30
          + LLL LA L F+++  P   G SKC
Sbjct: 2  KFLLLVLAALGFLTQVIPASAGGSKC 27


>gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]
          Length = 4265

 Score = 26.6 bits (57), Expect = 8.0
 Identities = 13/36 (36%), Positives = 24/36 (66%), Gaps = 4/36 (11%)

Query: 13   GLVFVSEAGPTGTGESKC-PLMVKVLDAVRGSPAIN 47
            GL+ V   GPTG+G+S C  ++   + +++G P+I+
Sbjct: 1857 GLMLV---GPTGSGKSTCYRVLAAAMTSLKGQPSIS 1889


>gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens]
          Length = 423

 Score = 26.6 bits (57), Expect = 8.0
 Identities = 16/40 (40%), Positives = 24/40 (60%), Gaps = 2/40 (5%)

Query: 4   HRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGS 43
           HRL  LCL+G   +++A  T  G   CP  +++L+A R S
Sbjct: 234 HRLQALCLSGCSNLTDASLTALG-LNCP-RLQILEAARCS 271


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.131    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,595,807
Number of Sequences: 37866
Number of extensions: 218533
Number of successful extensions: 459
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 457
Number of HSP's gapped (non-prelim): 9
length of query: 147
length of database: 18,247,518
effective HSP length: 93
effective length of query: 54
effective length of database: 14,725,980
effective search space: 795202920
effective search space used: 795202920
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.