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Search of human proteins with 4506953
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4506953 alpha-2,8-sialyltransferase 1 [Homo sapiens]
(356 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4506953 alpha-2,8-sialyltransferase 1 [Homo sapiens] 742 0.0
gi|54234057 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltrans... 274 8e-74
gi|28373101 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltrans... 256 3e-68
gi|5174677 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf... 175 5e-44
gi|110815855 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltran... 167 2e-41
gi|5031999 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf... 157 2e-38
gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [H... 70 3e-12
gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [... 64 3e-10
gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [H... 64 3e-10
gi|21264332 sialyltransferase 7A [Homo sapiens] 60 2e-09
gi|28373092 sialyltransferase 7D isoform a [Homo sapiens] 58 1e-08
gi|13569938 sialyltransferase 7E [Homo sapiens] 56 6e-08
gi|192448440 sialyltransferase 7B [Homo sapiens] 55 1e-07
gi|28373099 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltrans... 55 1e-07
gi|28373086 sialyltransferase 6 isoform i [Homo sapiens] 54 2e-07
gi|28373082 sialyltransferase 6 isoform g [Homo sapiens] 54 2e-07
gi|28373078 sialyltransferase 6 isoform f [Homo sapiens] 54 2e-07
gi|28373070 sialyltransferase 6 isoform b [Homo sapiens] 54 2e-07
gi|28373068 sialyltransferase 6 isoform a [Homo sapiens] 54 2e-07
gi|5454060 sialyltransferase 6 isoform j [Homo sapiens] 54 2e-07
gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 i... 51 1e-06
gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 ... 51 1e-06
gi|28373074 sialyltransferase 6 isoform d [Homo sapiens] 49 7e-06
gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens] 49 9e-06
gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2... 48 1e-05
gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 ... 48 1e-05
gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [H... 48 2e-05
gi|21361444 sialytransferase 7F [Homo sapiens] 47 3e-05
gi|229892273 sialyltransferase 7C isoform 1 [Homo sapiens] 47 3e-05
gi|28373094 sialyltransferase 7D isoform b [Homo sapiens] 43 5e-04
>gi|4506953 alpha-2,8-sialyltransferase 1 [Homo sapiens]
Length = 356
Score = 742 bits (1915), Expect = 0.0
Identities = 356/356 (100%), Positives = 356/356 (100%)
Query: 1 MSPCGRARRQTSRGAMAVLAWKFPRTRLPMGASALCVVVLCWLYIFPVYRLPNEKEIVQG 60
MSPCGRARRQTSRGAMAVLAWKFPRTRLPMGASALCVVVLCWLYIFPVYRLPNEKEIVQG
Sbjct: 1 MSPCGRARRQTSRGAMAVLAWKFPRTRLPMGASALCVVVLCWLYIFPVYRLPNEKEIVQG 60
Query: 61 VLQQGTAWRRNQTAARAFRKQMEDCCDPAHLFAMTKMNSPMGKSMWYDGEFLYSFTIDNS 120
VLQQGTAWRRNQTAARAFRKQMEDCCDPAHLFAMTKMNSPMGKSMWYDGEFLYSFTIDNS
Sbjct: 61 VLQQGTAWRRNQTAARAFRKQMEDCCDPAHLFAMTKMNSPMGKSMWYDGEFLYSFTIDNS 120
Query: 121 TYSLFPQATPFQLPLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGS 180
TYSLFPQATPFQLPLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGS
Sbjct: 121 TYSLFPQATPFQLPLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGS 180
Query: 181 KSQLVTANPSIIRQRFQNLLWSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLS 240
KSQLVTANPSIIRQRFQNLLWSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLS
Sbjct: 181 KSQLVTANPSIIRQRFQNLLWSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLS 240
Query: 241 DVGANQTVLFANPNFLRSIGKFWKSRGIHAKRLSTGLFLVSAALGLCEEVAIYGFWPFSV 300
DVGANQTVLFANPNFLRSIGKFWKSRGIHAKRLSTGLFLVSAALGLCEEVAIYGFWPFSV
Sbjct: 241 DVGANQTVLFANPNFLRSIGKFWKSRGIHAKRLSTGLFLVSAALGLCEEVAIYGFWPFSV 300
Query: 301 NMHEQPISHHYYDNVLPFSGFHAMPEEFLQLWYLHKIGALRMQLDPCEDTSLQPTS 356
NMHEQPISHHYYDNVLPFSGFHAMPEEFLQLWYLHKIGALRMQLDPCEDTSLQPTS
Sbjct: 301 NMHEQPISHHYYDNVLPFSGFHAMPEEFLQLWYLHKIGALRMQLDPCEDTSLQPTS 356
>gi|54234057 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 6 [Homo sapiens]
Length = 398
Score = 274 bits (701), Expect = 8e-74
Identities = 127/286 (44%), Positives = 183/286 (63%), Gaps = 1/286 (0%)
Query: 64 QGTAWRRNQTAARAFRKQMEDCCDPAHLFAMTKMNSPMGKSMWYDGEFLYSFTIDNSTYS 123
Q W+R FR ++ CCD F +++ N+P+G +M Y+ E I + +
Sbjct: 111 QSCPWKRQAEEYANFRAKLASCCDAVQNFVVSQNNTPVGTNMSYEVESKKEIPIKKNIFH 170
Query: 124 LFPQATPF-QLPLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKS 182
+FP + PF P +CAVVGNGGIL KS CG +ID+++FV RCNLPP + + +KDVGSK+
Sbjct: 171 MFPVSQPFVDYPYNQCAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKT 230
Query: 183 QLVTANPSIIRQRFQNLLWSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLSDV 242
LVT NPSII ++ NL + F++++ Y ++ +PAFS + T S +VYYTL +
Sbjct: 231 NLVTINPSIITLKYGNLKEKKALFLEDIATYGDAFFLLPAFSFRANTGTSFKVYYTLEES 290
Query: 243 GANQTVLFANPNFLRSIGKFWKSRGIHAKRLSTGLFLVSAALGLCEEVAIYGFWPFSVNM 302
A Q VLF +P +L+ + FW+++G+ A RLSTGL + S A+ LC+ V +YGFWPFS +
Sbjct: 291 KARQKVLFFHPKYLKDLALFWRTKGVTAYRLSTGLMITSVAVELCKNVKLYGFWPFSKTV 350
Query: 303 HEQPISHHYYDNVLPFSGFHAMPEEFLQLWYLHKIGALRMQLDPCE 348
+ P+SHHYYDN LP GFH MP+E+ Q+ LH G L++Q CE
Sbjct: 351 EDIPVSHHYYDNKLPKHGFHQMPKEYSQILQLHMKGILKLQFSKCE 396
>gi|28373101 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 5 [Homo sapiens]
Length = 376
Score = 256 bits (653), Expect = 3e-68
Identities = 127/282 (45%), Positives = 179/282 (63%), Gaps = 3/282 (1%)
Query: 68 WRRNQTAARAFRKQMEDCCD-PAHLFAMTKMNSPMGKSMWYDGEFLYSFTIDNSTYSLFP 126
W N + A F+ + CC+ PA LF T+ N+P+G + Y+ + + I+ + +FP
Sbjct: 93 WAMNISEANQFKSTLSRCCNAPAFLFT-TQKNTPLGTKLKYEVDTSGIYHINQEIFRMFP 151
Query: 127 QATPF-QLPLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQLV 185
+ P+ + KKCAVVGNGGILK S CGR+I+ A+FV RCNLPP+S +YT DVG K+ +V
Sbjct: 152 KDMPYYRSQFKKCAVVGNGGILKNSRCGREINSADFVFRCNLPPISEKYTMDVGVKTDVV 211
Query: 186 TANPSIIRQRFQNLLWSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLSDVGAN 245
T NPSII +RF L R+ F +++Y ++ + +PAF T+ S+RV Y L D +
Sbjct: 212 TVNPSIITERFHKLEKWRRPFYRVLQVYENASVLLPAFYNTRNTDVSIRVKYVLDDFESP 271
Query: 246 QTVLFANPNFLRSIGKFWKSRGIHAKRLSTGLFLVSAALGLCEEVAIYGFWPFSVNMHEQ 305
Q V + +P +L ++ ++W S G+ AKR+STGL LV+AAL LCEEV ++GFW F +N
Sbjct: 272 QAVYYFHPQYLVNVSRYWLSLGVRAKRISTGLILVTAALELCEEVHLFGFWAFPMNPSGL 331
Query: 306 PISHHYYDNVLPFSGFHAMPEEFLQLWYLHKIGALRMQLDPC 347
I+HHYYDNV P GFHAMP E +LH G LR+ C
Sbjct: 332 YITHHYYDNVKPRPGFHAMPSEIFNFLHLHSRGILRVHTGTC 373
>gi|5174677 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 2 [Homo sapiens]
Length = 375
Score = 175 bits (444), Expect = 5e-44
Identities = 96/304 (31%), Positives = 163/304 (53%), Gaps = 10/304 (3%)
Query: 53 NEKEIVQGVLQQGTAWRRNQTAARAFRKQMEDCCDPAHLFAMTKMNSPMGKSMWYDGEFL 112
+ + I + + WR NQT + RKQ+ D ++ K G + Y +
Sbjct: 71 SNESIKHNIQPASSKWRHNQTLSLRIRKQILKFLDAEKDISVLKGTLKPGDIIHYIFDRD 130
Query: 113 YSFTIDNSTYSLFPQATPFQLP-LKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLS 171
+ + + Y L P+ +P + CA+VGN G+L SGCG++ID +FV+RCNL P+
Sbjct: 131 STMNVSQNLYELLPRTSPLKNKHFGTCAIVGNSGVLLNSGCGQEIDAHSFVIRCNLAPVQ 190
Query: 172 SEYTKDVGSKSQLVTANPSIIRQRFQNLL---WSRKTFVDNMKIYNHSYIYMPAFSMKTG 228
EY +DVG K+ LVT NPS+I++ F++L+ W R+ + + N S +++PAF + G
Sbjct: 191 -EYARDVGLKTDLVTMNPSVIQRAFEDLVNATW-REKLLQRLHSLNGSILWIPAFMARGG 248
Query: 229 TEPSLRVYYTLSDVGANQTVLFANPNFLRSIGKFWKSRGIHAKRLSTGLFLVSAALGLCE 288
E V + N + + L ++ +W + +H KR +TGL + + A C+
Sbjct: 249 KERVEWVNELILKHHVNVRTAYPSLRLLHAVRGYWLTNKVHIKRPTTGLLMYTLATRFCK 308
Query: 289 EVAIYGFWPFSVNMHEQPISHHYYDNV----LPFSGFHAMPEEFLQLWYLHKIGALRMQL 344
++ +YGFWPF ++ ++ P+ +HYYD++ + H MP EF L LH+ GAL++ +
Sbjct: 309 QIYLYGFWPFPLDQNQNPVKYHYYDSLKYGYTSQASPHTMPLEFKALKSLHEQGALKLTV 368
Query: 345 DPCE 348
C+
Sbjct: 369 GQCD 372
>gi|110815855 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 3 [Homo sapiens]
Length = 380
Score = 167 bits (422), Expect = 2e-41
Identities = 99/308 (32%), Positives = 165/308 (53%), Gaps = 12/308 (3%)
Query: 51 LPNEKEIVQGVLQQGTAWRRNQTAARAFRKQMEDCCDPAHLFAMTKMNSPMGKSMWYD-G 109
+P + Q + ++ + W+ N+TA R+++ D F++TK + +G+ M YD
Sbjct: 73 VPITNSLTQELQEKPSKWKFNRTAFLHQRQEILQHVDVIKNFSLTKNSVRIGQLMHYDYS 132
Query: 110 EFLYSFTIDNSTYSLFPQATPFQLP-LKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLP 168
Y F+I N+ SL P +P CAVVGN GIL S CG++ID+++FV RCN
Sbjct: 133 SHKYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFA 192
Query: 169 PLSSEYTKDVGSKSQLVTANPSIIRQRFQNLLW--SRKTFVDNMKIYNHSYIYMPAFSMK 226
P + + +DVG K+ L T NPSI+ + + NLL R F ++K + + +++PAF
Sbjct: 193 PTEA-FQRDVGRKTNLTTFNPSILEKYYNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFH 251
Query: 227 TG-TEPSLRVYYTLSDVGANQTVLFANPNFLRSIGKFWKSRGIHAKRLSTGLFLVSAALG 285
T T V + + G + L N ++ + ++WK++ + KRLSTG+ + + A
Sbjct: 252 TSATVTRTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYWKNKHLSPKRLSTGILMYTLASA 311
Query: 286 LCEEVAIYGFWPFSVNMH-EQPISHHYYDN-----VLPFSGFHAMPEEFLQLWYLHKIGA 339
+CEE+ +YGFWPF + + + + +HYYD + H +P EF L+ +H G
Sbjct: 312 ICEEIHLYGFWPFGFDPNTREDLPYHYYDKKGTKFTTKWQESHQLPAEFQLLYRMHGEGL 371
Query: 340 LRMQLDPC 347
++ L C
Sbjct: 372 TKLTLSHC 379
>gi|5031999 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 4 isoform a [Homo sapiens]
Length = 359
Score = 157 bits (396), Expect = 2e-38
Identities = 92/288 (31%), Positives = 149/288 (51%), Gaps = 10/288 (3%)
Query: 68 WRRNQTAARAFRKQMEDCCDPAHLFAMTKMNSPMGKSMWYDGEFLYSFTIDNSTYSLFPQ 127
W+ N + RK + D ++ K + G + Y + + I + +SL P+
Sbjct: 71 WKINSSLVLEIRKNILRFLDAERDVSVVKSSFKPGDVIHYVLDRRRTLNISHDLHSLLPE 130
Query: 128 ATPFQ-LPLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQLVT 186
+P + K CAVVGN GIL S CG++ID NFV+RCNL P+ E+ DVG+KS +T
Sbjct: 131 VSPMKNRRFKTCAVVGNSGILLDSECGKEIDSHNFVIRCNLAPVV-EFAADVGTKSDFIT 189
Query: 187 ANPSIIRQRFQNLL--WSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLSDVGA 244
NPS++++ F R+ FV + + N S +++PAF +K G + V +
Sbjct: 190 MNPSVVQRAFGGFRNESDREKFVHRLSMLNDSVLWIPAFMVKGGEKHVEWVNALILKNKL 249
Query: 245 NQTVLFANPNFLRSIGKFWKSRGIHAKRLSTGLFLVSAALGLCEEVAIYGFWPFSVNMHE 304
+ + + ++ +W + + KR STGL + + A C+E+ +YGFWPF +++
Sbjct: 250 KVRTAYPSLRLIHAVRGYWLTNKVPIKRPSTGLLMYTLATRFCDEIHLYGFWPFPKDLNG 309
Query: 305 QPISHHYYDNVLPFSGF-----HAMPEEFLQLWYLHKIGALRMQLDPC 347
+ + +HYYD+ L + F H MP EF L LH GAL++ C
Sbjct: 310 KAVKYHYYDD-LKYRYFSNASPHRMPLEFKTLNVLHNRGALKLTTGKC 356
>gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [Homo
sapiens]
Length = 350
Score = 70.1 bits (170), Expect = 3e-12
Identities = 56/209 (26%), Positives = 93/209 (44%), Gaps = 43/209 (20%)
Query: 122 YSLFPQATPFQL----PLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKD 177
+ + P P++ ++CAVVGN G L+ SG G+ +D NF+MR N P + + +D
Sbjct: 132 FQIVPGENPYRFRDPHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAP-TVGFEQD 190
Query: 178 VGSK----------SQLVTANPSIIRQRFQ--NLLWSRKTFVDNMKIYNHSYIYMPAFSM 225
VGS+ ++ + AN S + F+ +LLW + + Y P S
Sbjct: 191 VGSRTTHHFMYPESAKNLPANVSFVLVPFKVLDLLW----IASALSTGQIRFTYAPVKSF 246
Query: 226 KTGTEPSLRVYYTLSDVGANQTVLFANPNFLRSIGKFWKSRGIHAKRLSTGLFLVSAALG 285
+ +++Y NP F + I W H + STG+ ++ AL
Sbjct: 247 LRVDKEKVQIY---------------NPAFFKYIHDRWTEH--HGRYPSTGMLVLFFALH 289
Query: 286 LCEEVAIYGFWPFSVNMHEQPISHHYYDN 314
+C+EV +YGF + HHY++N
Sbjct: 290 VCDEVNVYGF-----GADSRGNWHHYWEN 313
>gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
[Homo sapiens]
Length = 340
Score = 63.5 bits (153), Expect = 3e-10
Identities = 54/189 (28%), Positives = 86/189 (45%), Gaps = 35/189 (18%)
Query: 136 KKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQLVTANPSIIRQR 195
++CAVVGN G L++S G +ID +FV+R N P ++ + DVG+K+ P R+
Sbjct: 140 RRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAP-TAGFEADVGTKTTHHLVYPESFREL 198
Query: 196 FQN---LLWSRKTF-------VDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLSDVGAN 245
N +L KT +H+YI +PA +RV
Sbjct: 199 GDNVSMILVPFKTIDLEWVVSAITTGTISHTYIPVPA---------KIRV--------KQ 241
Query: 246 QTVLFANPNFLRSIGKFWKSRGIHAKRLSTGLFLVSAALGLCEEVAIYGFWPFSVNMHEQ 305
+L +P F++ + W H + STG+ V ++ +C+EV +YGF S
Sbjct: 242 DKILIYHPAFIKYVFDNWLQG--HGRYPSTGILSVIFSMHVCDEVDLYGFGADSKGNW-- 297
Query: 306 PISHHYYDN 314
HHY++N
Sbjct: 298 ---HHYWEN 303
>gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [Homo
sapiens]
Length = 340
Score = 63.5 bits (153), Expect = 3e-10
Identities = 54/189 (28%), Positives = 86/189 (45%), Gaps = 35/189 (18%)
Query: 136 KKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQLVTANPSIIRQR 195
++CAVVGN G L++S G +ID +FV+R N P ++ + DVG+K+ P R+
Sbjct: 140 RRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAP-TAGFEADVGTKTTHHLVYPESFREL 198
Query: 196 FQN---LLWSRKTF-------VDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLSDVGAN 245
N +L KT +H+YI +PA +RV
Sbjct: 199 GDNVSMILVPFKTIDLEWVVSAITTGTISHTYIPVPA---------KIRV--------KQ 241
Query: 246 QTVLFANPNFLRSIGKFWKSRGIHAKRLSTGLFLVSAALGLCEEVAIYGFWPFSVNMHEQ 305
+L +P F++ + W H + STG+ V ++ +C+EV +YGF S
Sbjct: 242 DKILIYHPAFIKYVFDNWLQG--HGRYPSTGILSVIFSMHVCDEVDLYGFGADSKGNW-- 297
Query: 306 PISHHYYDN 314
HHY++N
Sbjct: 298 ---HHYWEN 303
>gi|21264332 sialyltransferase 7A [Homo sapiens]
Length = 600
Score = 60.5 bits (145), Expect = 2e-09
Identities = 67/237 (28%), Positives = 109/237 (45%), Gaps = 28/237 (11%)
Query: 138 CAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQL-------VTANPS 190
CAVVGNGGIL S G++ID ++V R + L Y +DVG+++ +T +
Sbjct: 365 CAVVGNGGILNNSHMGQEIDSHDYVFRLS-GALIKGYEQDVGTRTSFYGFTAFSLTQSLL 423
Query: 191 IIRQR-FQNLLWSRKTFVDNMKIYNHSYIYMPAFSM-KTGTEPSL-----RVYYTLSDVG 243
I+ R F+N+ + + Y ++ A M +T +L R +
Sbjct: 424 ILGNRGFKNVPLGKDVRYLHFLEGTRDYEWLEALLMNQTVMSKNLFWFRHRPQEAFREAL 483
Query: 244 ANQTVLFANPNFLRSI-GKFWKSR---GIHAK--RLSTGLFLVSAALGLCEEVAIYGFWP 297
L +P+FLR + +F +S+ G H + R +TG L+ AL LC++V+ YGF
Sbjct: 484 HMDRYLLLHPDFLRYMKNRFLRSKTLDGAHWRIYRPTTGALLLLTALQLCDQVSAYGF-- 541
Query: 298 FSVNMHEQPISHHYYDNVLPFSGFHAMPEEFL--QLW-YLHKIGALRMQLDPCEDTS 351
+ + S HYYD F+ + L ++W LH G +R+ P T+
Sbjct: 542 --ITEGHERFSDHYYDTSWKRLIFYINHDFKLEREVWKRLHDEGIIRLYQRPGPGTA 596
>gi|28373092 sialyltransferase 7D isoform a [Homo sapiens]
Length = 302
Score = 58.2 bits (139), Expect = 1e-08
Identities = 59/210 (28%), Positives = 90/210 (42%), Gaps = 29/210 (13%)
Query: 120 STYSLFPQATPF-QLPLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDV 178
S YS P P + P + CAVV + G + SG G +ID A V R N P + + DV
Sbjct: 57 SGYSSVPDGKPLVREPCRSCAVVSSSGQMLGSGLGAEIDSAECVFRMNQAP-TVGFEADV 115
Query: 179 GSKSQL----VTANPSIIR---QRFQN------LLWSRKTFVDNMKIYNHSYIYMPAFSM 225
G +S L T+ P ++R FQ ++W + +D + + +Y
Sbjct: 116 GQRSTLRVVSHTSVPLLLRNYSHYFQKARDTLYMVWGQGRHMDRV-LGGRTY---RTLLQ 171
Query: 226 KTGTEPSLRVYYTLSDVGANQTVLFANPNFLRSIGKFWKSRGIHAKRLSTGLFLVSAALG 285
T P L+VY + + + + F GK + G LSTG F + AL
Sbjct: 172 LTRMYPGLQVY-----TFTERMMAYCDQIFQDETGKNRRQSG---SFLSTGWFTMILALE 223
Query: 286 LCEEVAIYGFWPFSV--NMHEQPISHHYYD 313
LCEE+ +YG S + +HY++
Sbjct: 224 LCEEIVVYGMVSDSYCREKSHPSVPYHYFE 253
>gi|13569938 sialyltransferase 7E [Homo sapiens]
Length = 336
Score = 55.8 bits (133), Expect = 6e-08
Identities = 50/202 (24%), Positives = 88/202 (43%), Gaps = 34/202 (16%)
Query: 130 PFQLPLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQLVTANP 189
P ++ + CA+V + G L S G QID+ V+R N P Y +DVG+++ L
Sbjct: 88 PLKMHCRDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRG-YGRDVGNRTSLRVIAH 146
Query: 190 SIIRQRFQN-------------LLWSRKTFV---DNMKIYNHSYIYMPAFSMKTGTEPSL 233
S I++ +N + W +++ ++YN+ ++ P L
Sbjct: 147 SSIQRILRNRHDLLNVSQGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVL-------PRL 199
Query: 234 RVYYTLSDVGANQTVLFANPNFLRSIGKFWKSRGIHAKRLSTGLFLVSAALGLCEEVAIY 293
+ + +L + F + GK R I LSTG F ++ AL LC+ + +Y
Sbjct: 200 KAFMI-----TRHKMLQFDELFKQETGK---DRKISNTWLSTGWFTMTIALELCDRINVY 251
Query: 294 GFWP--FSVNMHEQPISHHYYD 313
G P F + + + +HYY+
Sbjct: 252 GMVPPDFCRDPNHPSVPYHYYE 273
>gi|192448440 sialyltransferase 7B [Homo sapiens]
Length = 374
Score = 55.1 bits (131), Expect = 1e-07
Identities = 61/240 (25%), Positives = 105/240 (43%), Gaps = 32/240 (13%)
Query: 128 ATPFQLPLK--KCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQLV 185
A P P K +CAVVGNGGIL S G ID ++V R N + + +DVG+K+
Sbjct: 139 APPRDTPPKCIRCAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKG-FERDVGTKTSFY 197
Query: 186 TANPSIIRQRFQNLLWSRKTFVDNMKIYNHSYIYMPA--------------FSMKTGTEP 231
+ ++ + W+ F + + YI++P+ + G +
Sbjct: 198 GFTVNTMKNSLVS-YWN-LGFTSVPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDK 255
Query: 232 SLRVYYTLSDVGANQTVLFANPNFLRSI-GKFWKSRGIHAK-----RLSTGLFLVSAALG 285
R + + +P+F+ + +F KS+ I+ STG ++ AL
Sbjct: 256 GDRPHAYFGPEASASKFKLLHPDFISYLTERFLKSKLINTHFGDLYMPSTGALMLLTALH 315
Query: 286 LCEEVAIYGFWPFSVNMHEQPISHHYYDNVLPFSGFHAMPEEFLQ--LWY-LHKIGALRM 342
C++V+ YGF + + S HY++ + F+A + L+ LW LHK G L++
Sbjct: 316 TCDQVSAYGF----ITSNYWKFSDHYFERKMKPLIFYANHDLSLEAALWRDLHKAGILQL 371
>gi|28373099 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 4 isoform b [Homo sapiens]
Length = 168
Score = 54.7 bits (130), Expect = 1e-07
Identities = 32/98 (32%), Positives = 49/98 (50%), Gaps = 1/98 (1%)
Query: 68 WRRNQTAARAFRKQMEDCCDPAHLFAMTKMNSPMGKSMWYDGEFLYSFTIDNSTYSLFPQ 127
W+ N + RK + D ++ K + G + Y + + I + +SL P+
Sbjct: 71 WKINSSLVLEIRKNILRFLDAERDVSVVKSSFKPGDVIHYVLDRRRTLNISHDLHSLLPE 130
Query: 128 ATPFQ-LPLKKCAVVGNGGILKKSGCGRQIDEANFVMR 164
+P + K CAVVGN GIL S CG++ID NFV+R
Sbjct: 131 VSPMKNRRFKTCAVVGNSGILLDSECGKEIDSHNFVIR 168
>gi|28373086 sialyltransferase 6 isoform i [Homo sapiens]
Length = 413
Score = 53.9 bits (128), Expect = 2e-07
Identities = 47/189 (24%), Positives = 80/189 (42%), Gaps = 10/189 (5%)
Query: 133 LPLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQLVTANPSII 192
L ++C +VGNGG+L G +ID+ + V+R N P+ + KDVGSK+ L P
Sbjct: 193 LRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKG-FEKDVGSKTTLRITYPEGA 251
Query: 193 RQRFQNLLWSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLSDVGANQTVLFAN 252
QR + + K + ++ + + + N
Sbjct: 252 MQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILN 311
Query: 253 PNFLRS-----IGKFWKSRGIHAKRLST-GLFLVSAALGLCEEVAIYGFWPFSVNMHEQP 306
P F++ IG + + + + T G V+ AL C+EVA+ GF + ++ P
Sbjct: 312 PYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGF-GYDMSTPNAP 370
Query: 307 ISHHYYDNV 315
+ HYY+ V
Sbjct: 371 L--HYYETV 377
>gi|28373082 sialyltransferase 6 isoform g [Homo sapiens]
Length = 359
Score = 53.9 bits (128), Expect = 2e-07
Identities = 47/189 (24%), Positives = 80/189 (42%), Gaps = 10/189 (5%)
Query: 133 LPLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQLVTANPSII 192
L ++C +VGNGG+L G +ID+ + V+R N P+ + KDVGSK+ L P
Sbjct: 139 LRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKG-FEKDVGSKTTLRITYPEGA 197
Query: 193 RQRFQNLLWSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLSDVGANQTVLFAN 252
QR + + K + ++ + + + N
Sbjct: 198 MQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILN 257
Query: 253 PNFLRS-----IGKFWKSRGIHAKRLST-GLFLVSAALGLCEEVAIYGFWPFSVNMHEQP 306
P F++ IG + + + + T G V+ AL C+EVA+ GF + ++ P
Sbjct: 258 PYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGF-GYDMSTPNAP 316
Query: 307 ISHHYYDNV 315
+ HYY+ V
Sbjct: 317 L--HYYETV 323
>gi|28373078 sialyltransferase 6 isoform f [Homo sapiens]
Length = 429
Score = 53.9 bits (128), Expect = 2e-07
Identities = 47/189 (24%), Positives = 80/189 (42%), Gaps = 10/189 (5%)
Query: 133 LPLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQLVTANPSII 192
L ++C +VGNGG+L G +ID+ + V+R N P+ + KDVGSK+ L P
Sbjct: 209 LRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKG-FEKDVGSKTTLRITYPEGA 267
Query: 193 RQRFQNLLWSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLSDVGANQTVLFAN 252
QR + + K + ++ + + + N
Sbjct: 268 MQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILN 327
Query: 253 PNFLRS-----IGKFWKSRGIHAKRLST-GLFLVSAALGLCEEVAIYGFWPFSVNMHEQP 306
P F++ IG + + + + T G V+ AL C+EVA+ GF + ++ P
Sbjct: 328 PYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGF-GYDMSTPNAP 386
Query: 307 ISHHYYDNV 315
+ HYY+ V
Sbjct: 387 L--HYYETV 393
>gi|28373070 sialyltransferase 6 isoform b [Homo sapiens]
Length = 390
Score = 53.9 bits (128), Expect = 2e-07
Identities = 47/189 (24%), Positives = 80/189 (42%), Gaps = 10/189 (5%)
Query: 133 LPLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQLVTANPSII 192
L ++C +VGNGG+L G +ID+ + V+R N P+ + KDVGSK+ L P
Sbjct: 170 LRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKG-FEKDVGSKTTLRITYPEGA 228
Query: 193 RQRFQNLLWSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLSDVGANQTVLFAN 252
QR + + K + ++ + + + N
Sbjct: 229 MQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILN 288
Query: 253 PNFLRS-----IGKFWKSRGIHAKRLST-GLFLVSAALGLCEEVAIYGFWPFSVNMHEQP 306
P F++ IG + + + + T G V+ AL C+EVA+ GF + ++ P
Sbjct: 289 PYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGF-GYDMSTPNAP 347
Query: 307 ISHHYYDNV 315
+ HYY+ V
Sbjct: 348 L--HYYETV 354
>gi|28373068 sialyltransferase 6 isoform a [Homo sapiens]
Length = 444
Score = 53.9 bits (128), Expect = 2e-07
Identities = 47/189 (24%), Positives = 80/189 (42%), Gaps = 10/189 (5%)
Query: 133 LPLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQLVTANPSII 192
L ++C +VGNGG+L G +ID+ + V+R N P+ + KDVGSK+ L P
Sbjct: 224 LRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKG-FEKDVGSKTTLRITYPEGA 282
Query: 193 RQRFQNLLWSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLSDVGANQTVLFAN 252
QR + + K + ++ + + + N
Sbjct: 283 MQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILN 342
Query: 253 PNFLRS-----IGKFWKSRGIHAKRLST-GLFLVSAALGLCEEVAIYGFWPFSVNMHEQP 306
P F++ IG + + + + T G V+ AL C+EVA+ GF + ++ P
Sbjct: 343 PYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGF-GYDMSTPNAP 401
Query: 307 ISHHYYDNV 315
+ HYY+ V
Sbjct: 402 L--HYYETV 408
>gi|5454060 sialyltransferase 6 isoform j [Homo sapiens]
Length = 375
Score = 53.9 bits (128), Expect = 2e-07
Identities = 47/189 (24%), Positives = 80/189 (42%), Gaps = 10/189 (5%)
Query: 133 LPLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQLVTANPSII 192
L ++C +VGNGG+L G +ID+ + V+R N P+ + KDVGSK+ L P
Sbjct: 155 LRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKG-FEKDVGSKTTLRITYPEGA 213
Query: 193 RQRFQNLLWSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLSDVGANQTVLFAN 252
QR + + K + ++ + + + N
Sbjct: 214 MQRPEQYERDSLFVLAGFKWQDFKWLKYIVYKERVSASDGFWKSVATRVPKEPPEIRILN 273
Query: 253 PNFLRS-----IGKFWKSRGIHAKRLST-GLFLVSAALGLCEEVAIYGFWPFSVNMHEQP 306
P F++ IG + + + + T G V+ AL C+EVA+ GF + ++ P
Sbjct: 274 PYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVAVAGF-GYDMSTPNAP 332
Query: 307 ISHHYYDNV 315
+ HYY+ V
Sbjct: 333 L--HYYETV 339
>gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
isoform a [Homo sapiens]
Length = 406
Score = 51.2 bits (121), Expect = 1e-06
Identities = 48/205 (23%), Positives = 82/205 (40%), Gaps = 26/205 (12%)
Query: 134 PLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSK-------SQLVT 186
P +CAVV + G LK S GR+ID+ + V+R N P ++ + +DVG+K SQLVT
Sbjct: 180 PWGRCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAP-TANFQQDVGTKTTIRLMNSQLVT 238
Query: 187 ANPSIIRQRFQN----LLWSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLSDV 242
++ N ++W + ++ + P ++ Y T +
Sbjct: 239 TEKRFLKDSLYNEGILIVWDPSVYHSDIP----KWYQNPDYNF-------FNNYKTYRKL 287
Query: 243 GANQTVLFANPNF---LRSIGKFWKSRGIHAKRLSTGLFLVSAALGLCEEVAIYGFWPFS 299
NQ P L I + I S+G+ + + LC++V IY F P
Sbjct: 288 HPNQPFYILKPQMPWELWDILQEISPEEIQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSK 347
Query: 300 VNMHEQPISHHYYDNVLPFSGFHAM 324
++D+ +H +
Sbjct: 348 RKTDVCYYYQKFFDSACTMGAYHPL 372
>gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
isoform a [Homo sapiens]
Length = 406
Score = 51.2 bits (121), Expect = 1e-06
Identities = 48/205 (23%), Positives = 82/205 (40%), Gaps = 26/205 (12%)
Query: 134 PLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSK-------SQLVT 186
P +CAVV + G LK S GR+ID+ + V+R N P ++ + +DVG+K SQLVT
Sbjct: 180 PWGRCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAP-TANFQQDVGTKTTIRLMNSQLVT 238
Query: 187 ANPSIIRQRFQN----LLWSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLSDV 242
++ N ++W + ++ + P ++ Y T +
Sbjct: 239 TEKRFLKDSLYNEGILIVWDPSVYHSDIP----KWYQNPDYNF-------FNNYKTYRKL 287
Query: 243 GANQTVLFANPNF---LRSIGKFWKSRGIHAKRLSTGLFLVSAALGLCEEVAIYGFWPFS 299
NQ P L I + I S+G+ + + LC++V IY F P
Sbjct: 288 HPNQPFYILKPQMPWELWDILQEISPEEIQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSK 347
Query: 300 VNMHEQPISHHYYDNVLPFSGFHAM 324
++D+ +H +
Sbjct: 348 RKTDVCYYYQKFFDSACTMGAYHPL 372
>gi|28373074 sialyltransferase 6 isoform d [Homo sapiens]
Length = 277
Score = 48.9 bits (115), Expect = 7e-06
Identities = 25/63 (39%), Positives = 36/63 (57%), Gaps = 1/63 (1%)
Query: 133 LPLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQLVTANPSII 192
L ++C +VGNGG+L G +ID+ + V+R N P+ + KDVGSK+ L P
Sbjct: 155 LRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKG-FEKDVGSKTTLRITYPEGA 213
Query: 193 RQR 195
QR
Sbjct: 214 MQR 216
>gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens]
Length = 331
Score = 48.5 bits (114), Expect = 9e-06
Identities = 50/201 (24%), Positives = 82/201 (40%), Gaps = 37/201 (18%)
Query: 133 LPLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSE-------------YTKDVG 179
+P KKC VVGNGG+LK G +ID + ++R N P+ Y + V
Sbjct: 113 IPCKKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRTTFRLFYPESVF 172
Query: 180 SKSQLVTANPSIIRQRFQ--NLLWSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVY- 236
S N ++I F+ +L W + + + KI + + PA ++ +Y
Sbjct: 173 SDPIHNDPNTTVILTAFKPHDLRWLLELLMGD-KINTNGFWKKPALNL---------IYK 222
Query: 237 ---YTLSDVGANQTVLFANPNFLRSIGKFWKSRGIHAKRLSTGLFLVSAALGLCEEVAIY 293
+ D +T + +F + K K K +TG+ ++ A +C EV +
Sbjct: 223 PYQIRILDPFIIRTAAYELLHFPKVFPKNQK-----PKHPTTGIIAITLAFYICHEVHLA 277
Query: 294 GFWPFSVNMHEQPISHHYYDN 314
G F N + HYY N
Sbjct: 278 G---FKYNFSDLKSPLHYYGN 295
>gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform a [Homo sapiens]
Length = 529
Score = 48.1 bits (113), Expect = 1e-05
Identities = 48/216 (22%), Positives = 83/216 (38%), Gaps = 39/216 (18%)
Query: 135 LKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQLVTANPSIIRQ 194
L+ CAVV + G + S G +ID + V+R N P + Y KDVG+K+ + N I+
Sbjct: 293 LRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAP-TRGYEKDVGNKTTIRIINSQILTN 351
Query: 195 RFQNLL------------WSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLSDV 242
+ + W + N+ ++ P +++ T Y
Sbjct: 352 PSHHFIDSSLYKDVILVAWDPAPYSANLNLWYKK----PDYNLFT-------PYIQHRQR 400
Query: 243 GANQTVLFANPNFLRSIGKFW------KSRGIHAKRLSTGLFLVSAALGLCEEVAIYGFW 296
NQ +P F I + W I S+G + + +C EV +Y +
Sbjct: 401 NPNQPFYILHPKF---IWQLWDIIQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYI 457
Query: 297 PFSVNMHEQPISHH---YYDNVLPFSGFHAMPEEFL 329
P ++ + + H+ YYD +H + E L
Sbjct: 458 P---SVRQTELCHYHELYYDAACTLGAYHPLLYEKL 490
>gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform a [Homo sapiens]
Length = 529
Score = 48.1 bits (113), Expect = 1e-05
Identities = 48/216 (22%), Positives = 83/216 (38%), Gaps = 39/216 (18%)
Query: 135 LKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQLVTANPSIIRQ 194
L+ CAVV + G + S G +ID + V+R N P + Y KDVG+K+ + N I+
Sbjct: 293 LRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAP-TRGYEKDVGNKTTIRIINSQILTN 351
Query: 195 RFQNLL------------WSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLSDV 242
+ + W + N+ ++ P +++ T Y
Sbjct: 352 PSHHFIDSSLYKDVILVAWDPAPYSANLNLWYKK----PDYNLFT-------PYIQHRQR 400
Query: 243 GANQTVLFANPNFLRSIGKFW------KSRGIHAKRLSTGLFLVSAALGLCEEVAIYGFW 296
NQ +P F I + W I S+G + + +C EV +Y +
Sbjct: 401 NPNQPFYILHPKF---IWQLWDIIQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYI 457
Query: 297 PFSVNMHEQPISHH---YYDNVLPFSGFHAMPEEFL 329
P ++ + + H+ YYD +H + E L
Sbjct: 458 P---SVRQTELCHYHELYYDAACTLGAYHPLLYEKL 490
>gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [Homo
sapiens]
Length = 329
Score = 47.8 bits (112), Expect = 2e-05
Identities = 58/236 (24%), Positives = 99/236 (41%), Gaps = 49/236 (20%)
Query: 133 LPLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQL-------- 184
L ++C VVGNG L+ S G I++ + V+R N P++ Y DVGSK+ +
Sbjct: 111 LRCRRCVVVGNGHRLRNSSLGDAINKYDVVIRLNNAPVAG-YEGDVGSKTTMRLFYPESA 169
Query: 185 -----VTANPS----IIRQRFQNLLWSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRV 235
V NP ++ + + W D ++ + P
Sbjct: 170 HFDPKVENNPDTLLVLVAFKAMDFHWIETILSDKKRVRKGFWKQPP-------------- 215
Query: 236 YYTLSDVGANQTVLFANPNFLRSIGKFWKSRGIHAKRL-----STGLFLVSAALGLCEEV 290
+ DV Q + NP F+ S + R +TGL ++ AL LC+ V
Sbjct: 216 --LIWDVNPKQ-IRILNPFFMEIAADKLLSLPMQQPRKIKQKPTTGLLAITLALHLCDLV 272
Query: 291 AIYGF-WPFSVNMHEQPISHHYYDNV----LPFSGFHAMPEEFLQLWYLHKIGALR 341
I GF +P + N + + HYY+ + + SG H + +E L + + ++GA++
Sbjct: 273 HIAGFGYPDAYNKKQ---TIHYYEQITLKSMAGSG-HNVSQEALAIKRMLEMGAIK 324
>gi|21361444 sialytransferase 7F [Homo sapiens]
Length = 333
Score = 47.0 bits (110), Expect = 3e-05
Identities = 50/186 (26%), Positives = 78/186 (41%), Gaps = 16/186 (8%)
Query: 137 KCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQL-VTANPSIIRQR 195
+C +V + L + G +I+ A +R N P + Y+ DVG+K+ V A+ S+ R
Sbjct: 107 QCVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTTG-YSADVGNKTTYRVVAHSSVFR-- 163
Query: 196 FQNLLWSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLSDVGANQTVLFANPNF 255
+L + FV N + P M+ +RV V N +P
Sbjct: 164 ---VLRRPQEFV-NRTPETVFIFWGPPSKMQKPQGSLVRVIQRAGLVFPNMEAYAVSPGR 219
Query: 256 LRSI-----GKFWKSRGIHAKRLSTGLFLVSAALGLCEEVAIYGFWP---FSVNMHEQPI 307
+R G+ K R LSTG F + A+ LC+ V +YG P S Q +
Sbjct: 220 MRQFDDLFRGETGKDREKSHSWLSTGWFTMVIAVELCDHVHVYGMVPPNYCSQRPRLQRM 279
Query: 308 SHHYYD 313
+HYY+
Sbjct: 280 PYHYYE 285
>gi|229892273 sialyltransferase 7C isoform 1 [Homo sapiens]
Length = 305
Score = 46.6 bits (109), Expect = 3e-05
Identities = 45/196 (22%), Positives = 78/196 (39%), Gaps = 22/196 (11%)
Query: 130 PFQLPLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQ------ 183
P QL CA+V N G + G +ID ++ + R N P + Y +DVG +
Sbjct: 72 PLQLDCDLCAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAP-TKGYEEDVGRMTMIRVVSH 130
Query: 184 ----LVTANPSIIRQRFQNLLWSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTL 239
L+ NP + ++ NM+ + +Y G P+ ++Y T
Sbjct: 131 TSVPLLLKNPDYFFKEANTTIYVIWGPFRNMRKDGNGIVY-NMLKKTVGIYPNAQIYVT- 188
Query: 240 SDVGANQTVLFANPNFLRSIGKFWKSRGIHAKRLSTGLFLVSAALGLCEEVAIYGFWPFS 299
+ + + + F + GK G + LSTG F A+ C + +YG +
Sbjct: 189 ----TEKRMSYCDGVFKKETGKDRVQSGSY---LSTGWFTFLLAMDACYGIHVYGMINDT 241
Query: 300 VNMHE--QPISHHYYD 313
E + + +HYY+
Sbjct: 242 YCKTEGYRKVPYHYYE 257
>gi|28373094 sialyltransferase 7D isoform b [Homo sapiens]
Length = 218
Score = 42.7 bits (99), Expect = 5e-04
Identities = 48/179 (26%), Positives = 74/179 (41%), Gaps = 28/179 (15%)
Query: 150 SGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQLV----TANPSIIRQR---FQN---- 198
SG G +ID A V R N P + DVG +S L T+ P ++R FQ
Sbjct: 4 SGLGAEIDSAECVFRMNQAPTVG-FEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKARDT 62
Query: 199 --LLWSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLSDVGANQTVLFANPNFL 256
++W + +D + + +Y T P L+VY + + + + F
Sbjct: 63 LYMVWGQGRHMDRV-LGGRTY---RTLLQLTRMYPGLQVY-----TFTERMMAYCDQIFQ 113
Query: 257 RSIGKFWKSRGIHAKRLSTGLFLVSAALGLCEEVAIYGFWPFSV--NMHEQPISHHYYD 313
GK + G LSTG F + AL LCEE+ +YG S + +HY++
Sbjct: 114 DETGKNRRQSGSF---LSTGWFTMILALELCEEIVVYGMVSDSYCREKSHPSVPYHYFE 169
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.136 0.436
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,696,995
Number of Sequences: 37866
Number of extensions: 596895
Number of successful extensions: 1279
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1196
Number of HSP's gapped (non-prelim): 50
length of query: 356
length of database: 18,247,518
effective HSP length: 103
effective length of query: 253
effective length of database: 14,347,320
effective search space: 3629871960
effective search space used: 3629871960
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.