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Search of human proteins with 4506147
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]
(247 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4506147 protease, serine, 2 preproprotein [Homo sapiens] 508 e-144
gi|4506145 protease, serine, 1 preproprotein [Homo sapiens] 461 e-130
gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens] 457 e-129
gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens] 442 e-124
gi|91823048 kallikrein 14 preproprotein [Homo sapiens] 218 4e-57
gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprot... 216 2e-56
gi|4504875 kallikrein 1 preproprotein [Homo sapiens] 211 5e-55
gi|61744424 kallikrein-related peptidase 6 isoform A preproprote... 206 2e-53
gi|4506155 kallikrein-related peptidase 6 isoform A preproprotei... 206 2e-53
gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo ... 204 6e-53
gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo ... 204 6e-53
gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo sa... 204 6e-53
gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 204 7e-53
gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens] 204 7e-53
gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 204 7e-53
gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens] 199 2e-51
gi|21464127 kallikrein 8 isoform 2 [Homo sapiens] 198 3e-51
gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens] 198 3e-51
gi|11496281 kallikrein 13 precursor [Homo sapiens] 195 3e-50
gi|21327705 stratum corneum chymotryptic enzyme preproprotein [H... 194 6e-50
gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Ho... 194 6e-50
gi|22208987 kallikrein 12 isoform 2 [Homo sapiens] 193 1e-49
gi|4502173 prostate specific antigen isoform 1 preproprotein [Ho... 190 9e-49
gi|9665236 kallikrein 12 isoform 1 [Homo sapiens] 182 2e-46
gi|117422433 kallikrein-related peptidase 10 preproprotein [Homo... 182 2e-46
gi|22208984 kallikrein-related peptidase 10 preproprotein [Homo ... 182 2e-46
gi|22208982 kallikrein-related peptidase 10 preproprotein [Homo ... 182 2e-46
gi|29366812 kallikrein-related peptidase 9 [Homo sapiens] 180 9e-46
gi|4503649 coagulation factor IX preproprotein [Homo sapiens] 177 6e-45
gi|33667063 transmembrane protease, serine 9 [Homo sapiens] 177 1e-44
>gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]
Length = 247
Score = 508 bits (1307), Expect = e-144
Identities = 247/247 (100%), Positives = 247/247 (100%)
Query: 1 MNLLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGYHFCGGSLISEQWVVS 60
MNLLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGYHFCGGSLISEQWVVS
Sbjct: 1 MNLLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGYHFCGGSLISEQWVVS 60
Query: 61 AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVIN 120
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVIN
Sbjct: 61 AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVIN 120
Query: 121 SRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKIT 180
SRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKIT
Sbjct: 121 SRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKIT 180
Query: 181 NNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGYGCAQKNRPGVYTKVYNYVDWIK 240
NNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGYGCAQKNRPGVYTKVYNYVDWIK
Sbjct: 181 NNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGYGCAQKNRPGVYTKVYNYVDWIK 240
Query: 241 DTIAANS 247
DTIAANS
Sbjct: 241 DTIAANS 247
>gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]
Length = 247
Score = 461 bits (1186), Expect = e-130
Identities = 221/247 (89%), Positives = 236/247 (95%)
Query: 1 MNLLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGYHFCGGSLISEQWVVS 60
MN LLILTFVAAA+AAPFDDDDKIVGGY CEENSVPYQVSLNSGYHFCGGSLI+EQWVVS
Sbjct: 1 MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVS 60
Query: 61 AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVIN 120
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHP+Y+ +TL+NDI+LIKLSS AVIN
Sbjct: 61 AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVIN 120
Query: 121 SRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKIT 180
+RVS ISLPTAPPA GT+ LISGWGNT SSGADYPDELQCLDAPVLSQA+CEASYPGKIT
Sbjct: 121 ARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKIT 180
Query: 181 NNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGYGCAQKNRPGVYTKVYNYVDWIK 240
+NMFCVGFLEGGKDSCQGDSGGPVV NG+LQG+VSWG GCAQKN+PGVYTKVYNYV WIK
Sbjct: 181 SNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIK 240
Query: 241 DTIAANS 247
+TIAANS
Sbjct: 241 NTIAANS 247
>gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens]
Length = 247
Score = 457 bits (1176), Expect = e-129
Identities = 219/247 (88%), Positives = 231/247 (93%)
Query: 1 MNLLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGYHFCGGSLISEQWVVS 60
MN LIL FV AAVA PFDDDDKIVGGY CEENS+PYQVSLNSG HFCGGSLISEQWVVS
Sbjct: 1 MNPFLILAFVGAAVAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHFCGGSLISEQWVVS 60
Query: 61 AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVIN 120
A HCYK+RIQVRLGEHNI+VLEGNEQFINAAKIIRHPKYN TLDNDI+LIKLSSPAVIN
Sbjct: 61 AAHCYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVIN 120
Query: 121 SRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKIT 180
+RVS ISLPTAPPAAGTE LISGWGNTLS GADYPDEL+CLDAPVL+QAEC+ASYPGKIT
Sbjct: 121 ARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKIT 180
Query: 181 NNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGYGCAQKNRPGVYTKVYNYVDWIK 240
N+MFCVGFLEGGKDSCQ DSGGPVV NG+LQG+VSWG+GCA KNRPGVYTKVYNYVDWIK
Sbjct: 181 NSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIK 240
Query: 241 DTIAANS 247
DTIAANS
Sbjct: 241 DTIAANS 247
>gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]
Length = 304
Score = 442 bits (1138), Expect = e-124
Identities = 210/234 (89%), Positives = 222/234 (94%)
Query: 14 VAAPFDDDDKIVGGYICEENSVPYQVSLNSGYHFCGGSLISEQWVVSAGHCYKSRIQVRL 73
VA PFDDDDKIVGGY CEENS+PYQVSLNSG HFCGGSLISEQWVVSA HCYK+RIQVRL
Sbjct: 71 VAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHFCGGSLISEQWVVSAAHCYKTRIQVRL 130
Query: 74 GEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINSRVSAISLPTAPP 133
GEHNI+VLEGNEQFINAAKIIRHPKYN TLDNDI+LIKLSSPAVIN+RVS ISLPTAPP
Sbjct: 131 GEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPP 190
Query: 134 AAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITNNMFCVGFLEGGK 193
AAGTE LISGWGNTLS GADYPDEL+CLDAPVL+QAEC+ASYPGKITN+MFCVGFLEGGK
Sbjct: 191 AAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGK 250
Query: 194 DSCQGDSGGPVVSNGELQGIVSWGYGCAQKNRPGVYTKVYNYVDWIKDTIAANS 247
DSCQ DSGGPVV NG+LQG+VSWG+GCA KNRPGVYTKVYNYVDWIKDTIAANS
Sbjct: 251 DSCQRDSGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKDTIAANS 304
>gi|91823048 kallikrein 14 preproprotein [Homo sapiens]
Length = 267
Score = 218 bits (555), Expect = 4e-57
Identities = 107/245 (43%), Positives = 150/245 (61%), Gaps = 4/245 (1%)
Query: 3 LLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGYH---FCGGSLISEQWVV 59
LL L +A A+ +D++KI+GG+ C +S P+Q +L +G CGG+L+S QWV+
Sbjct: 20 LLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVI 79
Query: 60 SAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVI 119
+A HC + +QV LG+HN+ E +Q + + + HP YNSRT DND++L++L PA I
Sbjct: 80 TAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQQPARI 139
Query: 120 NSRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKI 179
V I + A + GT +SGWG S A YP LQC++ + C+ +YP I
Sbjct: 140 GRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRTI 199
Query: 180 TNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGY-GCAQKNRPGVYTKVYNYVDW 238
T M C G +GGKDSCQGDSGGP+V G+LQG+VSWG CA PGVYT + Y W
Sbjct: 200 TPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRSW 259
Query: 239 IKDTI 243
I++T+
Sbjct: 260 IEETM 264
>gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprotein
[Homo sapiens]
Length = 256
Score = 216 bits (549), Expect = 2e-56
Identities = 113/258 (43%), Positives = 156/258 (60%), Gaps = 14/258 (5%)
Query: 1 MNLLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGYHF-CGGSLISEQWVV 59
M LLL L+F+ A+ AA D DK++ G C +S P+QV+L F CG SLIS WV+
Sbjct: 1 MWLLLTLSFLLASTAA--QDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVL 58
Query: 60 SAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVI 119
SA HC ++VRLGEHN+ +G EQ +++I HP+Y +R+ NDI+L++L PA +
Sbjct: 59 SAAHCQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARL 118
Query: 120 NSRVSAISLPTAPPAAGTESLISGWG----------NTLSSGADYPDELQCLDAPVLSQA 169
N +V LPT P G ++SGWG + S PD L C + ++S
Sbjct: 119 NPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDT 178
Query: 170 ECEASYPGKITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWG-YGCAQKNRPGV 228
C+ SYPG++TN M C G G +SC+GDSGGP+V G LQGIVSWG C +PGV
Sbjct: 179 SCDKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGV 238
Query: 229 YTKVYNYVDWIKDTIAAN 246
YTKV +Y++WI++T+ N
Sbjct: 239 YTKVCHYLEWIRETMKRN 256
>gi|4504875 kallikrein 1 preproprotein [Homo sapiens]
Length = 262
Score = 211 bits (537), Expect = 5e-55
Identities = 109/262 (41%), Positives = 153/262 (58%), Gaps = 22/262 (8%)
Query: 3 LLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGYHF----CGGSLISEQWV 58
L L L+ A P +IVGG+ CE++S P+Q +L YHF CGG L+ QWV
Sbjct: 6 LCLALSLGGTGAAPPIQS--RIVGGWECEQHSQPWQAAL---YHFSTFQCGGILVHRQWV 60
Query: 59 VSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDN-----------D 107
++A HC Q+ LG HN+ E QF++ ++ HP +N L+N D
Sbjct: 61 LTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD 120
Query: 108 ILLIKLSSPA-VINSRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVL 166
++L++L+ PA I V + LPT P G+ L SGWG+ +PD+LQC+D +L
Sbjct: 121 LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKIL 180
Query: 167 SQAECEASYPGKITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGY-GCAQKNR 225
EC+ ++ K+T+ M CVG LEGGKD+C GDSGGP++ +G LQG+ SWGY C N+
Sbjct: 181 PNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNK 240
Query: 226 PGVYTKVYNYVDWIKDTIAANS 247
P V +V +YV WI+DTIA NS
Sbjct: 241 PSVAVRVLSYVKWIEDTIAENS 262
>gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 206 bits (523), Expect = 2e-53
Identities = 104/245 (42%), Positives = 154/245 (62%), Gaps = 7/245 (2%)
Query: 3 LLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSL-NSGYHFCGGSLISEQWVVSA 61
L+++L+ +AAA A ++ +K+V G C++ S PYQ +L SG+ CGG LI WV++A
Sbjct: 4 LMVVLSLIAAAWA---EEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTA 60
Query: 62 GHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINS 121
HC K +QV LG+HN+ E +++ + + + HP Y++ + D DI+L++L+ PA ++
Sbjct: 61 AHCKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSE 120
Query: 122 RVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITN 181
+ + L A T I GWG T + D+PD +QC ++S+ ECE +YPG+IT
Sbjct: 121 LIQPLPLERDCSANTTSCHILGWGKT--ADGDFPDTIQCAYIHLVSREECEHAYPGQITQ 178
Query: 182 NMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWG-YGCAQKNRPGVYTKVYNYVDWIK 240
NM C G + GKDSCQGDSGGP+V L+G+VSWG C K +PGVYT V Y +WI+
Sbjct: 179 NMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQ 238
Query: 241 DTIAA 245
TI A
Sbjct: 239 KTIQA 243
>gi|4506155 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 206 bits (523), Expect = 2e-53
Identities = 104/245 (42%), Positives = 154/245 (62%), Gaps = 7/245 (2%)
Query: 3 LLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSL-NSGYHFCGGSLISEQWVVSA 61
L+++L+ +AAA A ++ +K+V G C++ S PYQ +L SG+ CGG LI WV++A
Sbjct: 4 LMVVLSLIAAAWA---EEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTA 60
Query: 62 GHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINS 121
HC K +QV LG+HN+ E +++ + + + HP Y++ + D DI+L++L+ PA ++
Sbjct: 61 AHCKKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSE 120
Query: 122 RVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITN 181
+ + L A T I GWG T + D+PD +QC ++S+ ECE +YPG+IT
Sbjct: 121 LIQPLPLERDCSANTTSCHILGWGKT--ADGDFPDTIQCAYIHLVSREECEHAYPGQITQ 178
Query: 182 NMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWG-YGCAQKNRPGVYTKVYNYVDWIK 240
NM C G + GKDSCQGDSGGP+V L+G+VSWG C K +PGVYT V Y +WI+
Sbjct: 179 NMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQ 238
Query: 241 DTIAA 245
TI A
Sbjct: 239 KTIQA 243
>gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 204 bits (519), Expect = 6e-53
Identities = 104/233 (44%), Positives = 144/233 (61%), Gaps = 5/233 (2%)
Query: 19 DDDDKIVGGYICEENSVPYQVSL--NSGYHFCGGSLISEQWVVSAGHCYKSRIQVRLGEH 76
D +I+ G C+ ++ P+Q +L +CG L+ QW+++A HC K +VRLG +
Sbjct: 62 DSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHY 121
Query: 77 NIE-VLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINSRVSAISLPTAPPAA 135
++ V E +Q K I HP Y+ ND++LIKL+ V I++ + P+A
Sbjct: 122 SLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSA 181
Query: 136 GTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITNNMFCVGFLEGGKDS 195
GT+ L+SGWG T S +P LQCL+ VLSQ CE +YP +I + MFC G + G+DS
Sbjct: 182 GTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD-KAGRDS 240
Query: 196 CQGDSGGPVVSNGELQGIVSWG-YGCAQKNRPGVYTKVYNYVDWIKDTIAANS 247
CQGDSGGPVV NG LQG+VSWG Y CA+ NRPGVYT + + WI++TI ANS
Sbjct: 241 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS 293
>gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 204 bits (519), Expect = 6e-53
Identities = 104/233 (44%), Positives = 144/233 (61%), Gaps = 5/233 (2%)
Query: 19 DDDDKIVGGYICEENSVPYQVSL--NSGYHFCGGSLISEQWVVSAGHCYKSRIQVRLGEH 76
D +I+ G C+ ++ P+Q +L +CG L+ QW+++A HC K +VRLG +
Sbjct: 62 DSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHY 121
Query: 77 NIE-VLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINSRVSAISLPTAPPAA 135
++ V E +Q K I HP Y+ ND++LIKL+ V I++ + P+A
Sbjct: 122 SLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSA 181
Query: 136 GTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITNNMFCVGFLEGGKDS 195
GT+ L+SGWG T S +P LQCL+ VLSQ CE +YP +I + MFC G + G+DS
Sbjct: 182 GTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD-KAGRDS 240
Query: 196 CQGDSGGPVVSNGELQGIVSWG-YGCAQKNRPGVYTKVYNYVDWIKDTIAANS 247
CQGDSGGPVV NG LQG+VSWG Y CA+ NRPGVYT + + WI++TI ANS
Sbjct: 241 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS 293
>gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 204 bits (519), Expect = 6e-53
Identities = 104/233 (44%), Positives = 144/233 (61%), Gaps = 5/233 (2%)
Query: 19 DDDDKIVGGYICEENSVPYQVSL--NSGYHFCGGSLISEQWVVSAGHCYKSRIQVRLGEH 76
D +I+ G C+ ++ P+Q +L +CG L+ QW+++A HC K +VRLG +
Sbjct: 62 DSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHY 121
Query: 77 NIE-VLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINSRVSAISLPTAPPAA 135
++ V E +Q K I HP Y+ ND++LIKL+ V I++ + P+A
Sbjct: 122 SLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSA 181
Query: 136 GTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITNNMFCVGFLEGGKDS 195
GT+ L+SGWG T S +P LQCL+ VLSQ CE +YP +I + MFC G + G+DS
Sbjct: 182 GTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD-KAGRDS 240
Query: 196 CQGDSGGPVVSNGELQGIVSWG-YGCAQKNRPGVYTKVYNYVDWIKDTIAANS 247
CQGDSGGPVV NG LQG+VSWG Y CA+ NRPGVYT + + WI++TI ANS
Sbjct: 241 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS 293
>gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 204 bits (518), Expect = 7e-53
Identities = 107/250 (42%), Positives = 151/250 (60%), Gaps = 9/250 (3%)
Query: 3 LLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGYHF-CGGSLISEQWVVSA 61
L LIL +A + + +I+ G+ C+ +S P+Q +L CG +LI+ +W+++A
Sbjct: 4 LQLILLALATGLVG---GETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTA 60
Query: 62 GHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLD----NDILLIKLSSPA 117
HC K R V LG+HN++ EG EQ A + HP +N+ + NDI+L+K++SP
Sbjct: 61 AHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPV 120
Query: 118 VINSRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPG 177
I V ++L + AGT LISGWG+T S P L+C + ++ +CE +YPG
Sbjct: 121 SITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPG 180
Query: 178 KITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGYG-CAQKNRPGVYTKVYNYV 236
IT+ M C EGGKDSCQGDSGGP+V N LQGI+SWG CA +PGVYTKV YV
Sbjct: 181 NITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYV 240
Query: 237 DWIKDTIAAN 246
DWI++T+ N
Sbjct: 241 DWIQETMKNN 250
>gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens]
Length = 282
Score = 204 bits (518), Expect = 7e-53
Identities = 107/250 (42%), Positives = 151/250 (60%), Gaps = 9/250 (3%)
Query: 3 LLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGYHF-CGGSLISEQWVVSA 61
L LIL +A + + +I+ G+ C+ +S P+Q +L CG +LI+ +W+++A
Sbjct: 36 LQLILLALATGLVG---GETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTA 92
Query: 62 GHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLD----NDILLIKLSSPA 117
HC K R V LG+HN++ EG EQ A + HP +N+ + NDI+L+K++SP
Sbjct: 93 AHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPV 152
Query: 118 VINSRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPG 177
I V ++L + AGT LISGWG+T S P L+C + ++ +CE +YPG
Sbjct: 153 SITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPG 212
Query: 178 KITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGYG-CAQKNRPGVYTKVYNYV 236
IT+ M C EGGKDSCQGDSGGP+V N LQGI+SWG CA +PGVYTKV YV
Sbjct: 213 NITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYV 272
Query: 237 DWIKDTIAAN 246
DWI++T+ N
Sbjct: 273 DWIQETMKNN 282
>gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 204 bits (518), Expect = 7e-53
Identities = 107/250 (42%), Positives = 151/250 (60%), Gaps = 9/250 (3%)
Query: 3 LLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGYHF-CGGSLISEQWVVSA 61
L LIL +A + + +I+ G+ C+ +S P+Q +L CG +LI+ +W+++A
Sbjct: 4 LQLILLALATGLVG---GETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTA 60
Query: 62 GHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLD----NDILLIKLSSPA 117
HC K R V LG+HN++ EG EQ A + HP +N+ + NDI+L+K++SP
Sbjct: 61 AHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPV 120
Query: 118 VINSRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPG 177
I V ++L + AGT LISGWG+T S P L+C + ++ +CE +YPG
Sbjct: 121 SITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPG 180
Query: 178 KITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGYG-CAQKNRPGVYTKVYNYV 236
IT+ M C EGGKDSCQGDSGGP+V N LQGI+SWG CA +PGVYTKV YV
Sbjct: 181 NITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYV 240
Query: 237 DWIKDTIAAN 246
DWI++T+ N
Sbjct: 241 DWIQETMKNN 250
>gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens]
Length = 261
Score = 199 bits (505), Expect = 2e-51
Identities = 107/237 (45%), Positives = 136/237 (57%), Gaps = 13/237 (5%)
Query: 23 KIVGGYICEENSVPYQVSLNS-GYHFCGGSLISEQWVVSAGHCYKSRIQVRLGEHNIEVL 81
+IVGG+ CE++S P+QV++ S G+ CGG L+ QWV++A HC K QV LG HN+
Sbjct: 24 RIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEP 83
Query: 82 EGNEQFINAAKIIRHPKYNSRTL-----------DNDILLIKLSSPAVINSRVSAISLPT 130
E Q + + HP YN L +D++L++LS PA I V + LPT
Sbjct: 84 EDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPT 143
Query: 131 APPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITNNMFCVGFLE 190
PA GT SGWG+ P LQC+ +LS C +Y K+T M C G
Sbjct: 144 QEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWT 203
Query: 191 GGKDSCQGDSGGPVVSNGELQGIVSWG-YGCAQKNRPGVYTKVYNYVDWIKDTIAAN 246
GGKD+C GDSGGP+V NG LQGI SWG CA +P VYTKV +Y WIKDTIAAN
Sbjct: 204 GGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260
>gi|21464127 kallikrein 8 isoform 2 [Homo sapiens]
Length = 305
Score = 198 bits (504), Expect = 3e-51
Identities = 96/230 (41%), Positives = 143/230 (62%), Gaps = 6/230 (2%)
Query: 21 DDKIVGGYICEENSVPYQVSLNSGYHF-CGGSLISEQWVVSAGHCYKSRIQVRLGEHNIE 79
+DK++GG+ C+ +S P+Q +L G CGG L+ WV++A HC K + VRLG+H+++
Sbjct: 75 EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQ 134
Query: 80 VLEGNEQFINAAKIIRHPKYNSRTLDN---DILLIKLSSPAVINSRVSAISLPTAPPAAG 136
+G EQ I + I HP YNS +++ D++L++L A + S+V ISL G
Sbjct: 135 NKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPG 194
Query: 137 TESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITNNMFCVGFLEGGKDSC 196
+ +SGWG S ++PD L C + + Q +CE +YPG+IT+ M C G +G D+C
Sbjct: 195 QKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGA-DTC 253
Query: 197 QGDSGGPVVSNGELQGIVSWGYG-CAQKNRPGVYTKVYNYVDWIKDTIAA 245
QGDSGGP+V +G LQGI SWG C + ++PGVYT + Y+DWIK I +
Sbjct: 254 QGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGS 303
>gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens]
Length = 260
Score = 198 bits (504), Expect = 3e-51
Identities = 96/230 (41%), Positives = 143/230 (62%), Gaps = 6/230 (2%)
Query: 21 DDKIVGGYICEENSVPYQVSLNSGYHF-CGGSLISEQWVVSAGHCYKSRIQVRLGEHNIE 79
+DK++GG+ C+ +S P+Q +L G CGG L+ WV++A HC K + VRLG+H+++
Sbjct: 30 EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQ 89
Query: 80 VLEGNEQFINAAKIIRHPKYNSRTLDN---DILLIKLSSPAVINSRVSAISLPTAPPAAG 136
+G EQ I + I HP YNS +++ D++L++L A + S+V ISL G
Sbjct: 90 NKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPG 149
Query: 137 TESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITNNMFCVGFLEGGKDSC 196
+ +SGWG S ++PD L C + + Q +CE +YPG+IT+ M C G +G D+C
Sbjct: 150 QKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGA-DTC 208
Query: 197 QGDSGGPVVSNGELQGIVSWGYG-CAQKNRPGVYTKVYNYVDWIKDTIAA 245
QGDSGGP+V +G LQGI SWG C + ++PGVYT + Y+DWIK I +
Sbjct: 209 QGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGS 258
>gi|11496281 kallikrein 13 precursor [Homo sapiens]
Length = 277
Score = 195 bits (496), Expect = 3e-50
Identities = 101/225 (44%), Positives = 133/225 (59%), Gaps = 7/225 (3%)
Query: 26 GGYICEENSVPYQVSLN-SGYHFCGGSLISEQWVVSAGHCYKSRIQVRLGEHNIEVLEGN 84
GGY C +S P+Q +L G CGG L+ +WV++A HC K ++V LG+H + +E
Sbjct: 38 GGYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAG 97
Query: 85 EQFINAAKIIRHPKYNSRTL----DNDILLIKLSSPAVINSRVSAISLP-TAPPAAGTES 139
EQ I HP+Y D+DI+L++L SP + + + L GT
Sbjct: 98 EQVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTC 157
Query: 140 LISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITNNMFCVGFLEGGKDSCQGD 199
+SGWG T S +YP LQC + + S EC YPGKIT+NM C G EGGKDSC+GD
Sbjct: 158 RVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGD 217
Query: 200 SGGPVVSNGELQGIVSWG-YGCAQKNRPGVYTKVYNYVDWIKDTI 243
SGGP+V N L GIVSWG + C Q +RPGVYT+V YV WI++TI
Sbjct: 218 SGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETI 262
>gi|21327705 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 194 bits (493), Expect = 6e-50
Identities = 98/243 (40%), Positives = 142/243 (58%), Gaps = 4/243 (1%)
Query: 3 LLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGYHF-CGGSLISEQWVVSA 61
L ++L +A A DKI+ G C S P+QV+L SG CGG L++E+WV++A
Sbjct: 9 LQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTA 68
Query: 62 GHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINS 121
HC + V LG + + Q I A+K RHP Y+++T ND++L+KL+S A ++S
Sbjct: 69 AHCKMNEYTVHLGSDTLG--DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSS 126
Query: 122 RVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITN 181
V + LP+ GT +SGWG T S +P +L C+D ++S +C Y + N
Sbjct: 127 MVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLEN 186
Query: 182 NMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWG-YGCAQKNRPGVYTKVYNYVDWIK 240
+M C G + K++C GDSGGP+V G LQG+VSWG + C Q N PGVYT+V + WI
Sbjct: 187 SMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWIN 246
Query: 241 DTI 243
DT+
Sbjct: 247 DTM 249
>gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 194 bits (493), Expect = 6e-50
Identities = 98/243 (40%), Positives = 142/243 (58%), Gaps = 4/243 (1%)
Query: 3 LLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGYHF-CGGSLISEQWVVSA 61
L ++L +A A DKI+ G C S P+QV+L SG CGG L++E+WV++A
Sbjct: 9 LQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTA 68
Query: 62 GHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINS 121
HC + V LG + + Q I A+K RHP Y+++T ND++L+KL+S A ++S
Sbjct: 69 AHCKMNEYTVHLGSDTLG--DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSS 126
Query: 122 RVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITN 181
V + LP+ GT +SGWG T S +P +L C+D ++S +C Y + N
Sbjct: 127 MVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLEN 186
Query: 182 NMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWG-YGCAQKNRPGVYTKVYNYVDWIK 240
+M C G + K++C GDSGGP+V G LQG+VSWG + C Q N PGVYT+V + WI
Sbjct: 187 SMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWIN 246
Query: 241 DTI 243
DT+
Sbjct: 247 DTM 249
>gi|22208987 kallikrein 12 isoform 2 [Homo sapiens]
Length = 248
Score = 193 bits (491), Expect = 1e-49
Identities = 106/245 (43%), Positives = 144/245 (58%), Gaps = 10/245 (4%)
Query: 1 MNLLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGYHF-CGGSLISEQWVV 59
+++ L+L + + AA KI G C NS P+QV L G CGG LI +WV+
Sbjct: 3 LSIFLLLCVLGLSQAAT----PKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVL 58
Query: 60 SAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKY--NSRTLDNDILLIKLSSPA 117
+A HC SR VRLGEH++ L+ EQ ++ + HP Y S + ++D+ L++L P
Sbjct: 59 TAAHCSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPV 118
Query: 118 VINSRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPG 177
+ S V + LP AGTE +SGWG T +PD LQCL+ ++S A C YPG
Sbjct: 119 RVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPG 178
Query: 178 KITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGY--GCAQKNRPGVYTKVYNY 235
+IT+NM C G + G+D+CQGDSGGP+V G LQG+VSWG C Q PGVYT + Y
Sbjct: 179 RITSNMVCAGGVP-GQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKY 237
Query: 236 VDWIK 240
VDWI+
Sbjct: 238 VDWIR 242
>gi|4502173 prostate specific antigen isoform 1 preproprotein [Homo
sapiens]
Length = 261
Score = 190 bits (483), Expect = 9e-49
Identities = 106/257 (41%), Positives = 142/257 (55%), Gaps = 17/257 (6%)
Query: 3 LLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNS-GYHFCGGSLISEQWVVSA 61
L L +T++ AA +IVGG+ CE++S P+QV + S G CGG L+ QWV++A
Sbjct: 8 LTLSVTWIGAAPLIL----SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTA 63
Query: 62 GHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDN-----------DILL 110
HC +++ + LG H++ E Q + HP Y+ L N D++L
Sbjct: 64 AHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLML 123
Query: 111 IKLSSPAVINSRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAE 170
++LS PA + V + LPT PA GT SGWG+ P +LQC+D V+S
Sbjct: 124 LRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDV 183
Query: 171 CEASYPGKITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWG-YGCAQKNRPGVY 229
C +P K+T M C G GGK +C GDSGGP+V NG LQGI SWG CA RP +Y
Sbjct: 184 CAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLY 243
Query: 230 TKVYNYVDWIKDTIAAN 246
TKV +Y WIKDTI AN
Sbjct: 244 TKVVHYRKWIKDTIVAN 260
>gi|9665236 kallikrein 12 isoform 1 [Homo sapiens]
Length = 254
Score = 182 bits (463), Expect = 2e-46
Identities = 102/239 (42%), Positives = 139/239 (58%), Gaps = 10/239 (4%)
Query: 1 MNLLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGYHF-CGGSLISEQWVV 59
+++ L+L + + AA KI G C NS P+QV L G CGG LI +WV+
Sbjct: 3 LSIFLLLCVLGLSQAAT----PKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVL 58
Query: 60 SAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKY--NSRTLDNDILLIKLSSPA 117
+A HC SR VRLGEH++ L+ EQ ++ + HP Y S + ++D+ L++L P
Sbjct: 59 TAAHCSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPV 118
Query: 118 VINSRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPG 177
+ S V + LP AGTE +SGWG T +PD LQCL+ ++S A C YPG
Sbjct: 119 RVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPG 178
Query: 178 KITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGY--GCAQKNRPGVYTKVYN 234
+IT+NM C G + G+D+CQGDSGGP+V G LQG+VSWG C Q PGVYT + N
Sbjct: 179 RITSNMVCAGGVP-GQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICN 236
>gi|117422433 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 182 bits (462), Expect = 2e-46
Identities = 99/256 (38%), Positives = 141/256 (55%), Gaps = 14/256 (5%)
Query: 3 LLLILTFVAAAVAAPFDDD--DKIVGGYICEENSVPYQVSLNSGYHF-CGGSLISEQWVV 59
LL+ + A A P +D D G C S P+QVSL +G F C G L+ + WV+
Sbjct: 23 LLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVL 82
Query: 60 SAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNS--------RTLDNDILLI 111
+A HC + R+G+ ++ +L+G EQ + + HPKY+ RT ++D++L+
Sbjct: 83 TAAHCGNKPLWARVGDDHLLLLQG-EQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLL 141
Query: 112 KLSSPAVINSRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAEC 171
KL+ P V+ RV A+ LP G + ++GWG T + Y L C +LS EC
Sbjct: 142 KLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKEC 201
Query: 172 EASYPGKITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWG-YGCAQKNRPGVYT 230
E YPG +TNNM C G L+ G+D CQ DSGGP+V + LQGI+SWG Y C P VYT
Sbjct: 202 EVFYPGVVTNNMICAG-LDRGQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYT 260
Query: 231 KVYNYVDWIKDTIAAN 246
++ Y+ WI I +N
Sbjct: 261 QICKYMSWINKVIRSN 276
>gi|22208984 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 182 bits (462), Expect = 2e-46
Identities = 99/256 (38%), Positives = 141/256 (55%), Gaps = 14/256 (5%)
Query: 3 LLLILTFVAAAVAAPFDDD--DKIVGGYICEENSVPYQVSLNSGYHF-CGGSLISEQWVV 59
LL+ + A A P +D D G C S P+QVSL +G F C G L+ + WV+
Sbjct: 23 LLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVL 82
Query: 60 SAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNS--------RTLDNDILLI 111
+A HC + R+G+ ++ +L+G EQ + + HPKY+ RT ++D++L+
Sbjct: 83 TAAHCGNKPLWARVGDDHLLLLQG-EQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLL 141
Query: 112 KLSSPAVINSRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAEC 171
KL+ P V+ RV A+ LP G + ++GWG T + Y L C +LS EC
Sbjct: 142 KLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKEC 201
Query: 172 EASYPGKITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWG-YGCAQKNRPGVYT 230
E YPG +TNNM C G L+ G+D CQ DSGGP+V + LQGI+SWG Y C P VYT
Sbjct: 202 EVFYPGVVTNNMICAG-LDRGQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYT 260
Query: 231 KVYNYVDWIKDTIAAN 246
++ Y+ WI I +N
Sbjct: 261 QICKYMSWINKVIRSN 276
>gi|22208982 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 182 bits (462), Expect = 2e-46
Identities = 99/256 (38%), Positives = 141/256 (55%), Gaps = 14/256 (5%)
Query: 3 LLLILTFVAAAVAAPFDDD--DKIVGGYICEENSVPYQVSLNSGYHF-CGGSLISEQWVV 59
LL+ + A A P +D D G C S P+QVSL +G F C G L+ + WV+
Sbjct: 23 LLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVL 82
Query: 60 SAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNS--------RTLDNDILLI 111
+A HC + R+G+ ++ +L+G EQ + + HPKY+ RT ++D++L+
Sbjct: 83 TAAHCGNKPLWARVGDDHLLLLQG-EQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLL 141
Query: 112 KLSSPAVINSRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAEC 171
KL+ P V+ RV A+ LP G + ++GWG T + Y L C +LS EC
Sbjct: 142 KLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKEC 201
Query: 172 EASYPGKITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWG-YGCAQKNRPGVYT 230
E YPG +TNNM C G L+ G+D CQ DSGGP+V + LQGI+SWG Y C P VYT
Sbjct: 202 EVFYPGVVTNNMICAG-LDRGQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYT 260
Query: 231 KVYNYVDWIKDTIAAN 246
++ Y+ WI I +N
Sbjct: 261 QICKYMSWINKVIRSN 276
>gi|29366812 kallikrein-related peptidase 9 [Homo sapiens]
Length = 250
Score = 180 bits (457), Expect = 9e-46
Identities = 95/230 (41%), Positives = 133/230 (57%), Gaps = 12/230 (5%)
Query: 21 DDKIVGGYICEENSVPYQVSLNSGYH----FCGGSLISEQWVVSAGHCYKSRIQVRLGEH 76
D + +G C NS P+Q L +H FCG +LIS++W+++A HC K + VRLGEH
Sbjct: 20 DTRAIGAEECRPNSQPWQAGL---FHLTRLFCGATLISDRWLLTAAHCRKPYLWVRLGEH 76
Query: 77 NIEVLEGNEQFINAAKIIRHPKYNSRTLDND----ILLIKLSSPAVINSRVSAISLPTAP 132
++ EG EQ HP +N ND I+LI+L A ++ V ++L
Sbjct: 77 HLWKWEGPEQLFRVTDFFPHPGFNKDLSANDHNDDIMLIRLPRQARLSPAVQPLNLSQTC 136
Query: 133 PAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITNNMFCVGFLEGG 192
+ G + LISGWG S A +P LQC + +L C +YPG I+++M C G EGG
Sbjct: 137 VSPGMQCLISGWGAVSSPKALFPVTLQCANISILENKLCHWAYPGHISDSMLCAGLWEGG 196
Query: 193 KDSCQGDSGGPVVSNGELQGIVSWG-YGCAQKNRPGVYTKVYNYVDWIKD 241
+ SCQGDSGGP+V NG L G+VS G C++ RP VYT V +Y+DWI++
Sbjct: 197 RGSCQGDSGGPLVCNGTLAGVVSGGAEPCSRPRRPAVYTSVCHYLDWIQE 246
>gi|4503649 coagulation factor IX preproprotein [Homo sapiens]
Length = 461
Score = 177 bits (450), Expect = 6e-45
Identities = 101/237 (42%), Positives = 138/237 (58%), Gaps = 14/237 (5%)
Query: 18 FDDDDKIVGGYICEENSVPYQVSLNSGYH-FCGGSLISEQWVVSAGHCYKSRIQVRL--G 74
F+D ++VGG + P+QV LN FCGGS+++E+W+V+A HC ++ +++ + G
Sbjct: 221 FNDFTRVVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAG 280
Query: 75 EHNIEVLEGNEQFINAAKIIRHPKYNS--RTLDNDILLIKLSSPAVINSRVSAISLP--- 129
EHNIE E EQ N +II H YN+ ++DI L++L P V+NS V+ I +
Sbjct: 281 EHNIEETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKE 340
Query: 130 -TAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITNNMFCVGF 188
T +SGWG G LQ L P++ +A C S I NNMFC GF
Sbjct: 341 YTNIFLKFGSGYVSGWGRVFHKGRSAL-VLQYLRVPLVDRATCLRSTKFTIYNNMFCAGF 399
Query: 189 LEGGKDSCQGDSGGPVVSNGE----LQGIVSWGYGCAQKNRPGVYTKVYNYVDWIKD 241
EGG+DSCQGDSGGP V+ E L GI+SWG CA K + G+YTKV YV+WIK+
Sbjct: 400 HEGGRDSCQGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKE 456
>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
Length = 1059
Score = 177 bits (448), Expect = 1e-44
Identities = 89/235 (37%), Positives = 132/235 (56%), Gaps = 12/235 (5%)
Query: 23 KIVGGYICEENSVPYQVSLNSGY-HFCGGSLISEQWVVSAGHCYK----SRIQVRLGEHN 77
++VGG+ VP+QVSL G HFCG +++ ++W++SA HC+ +++ LG +
Sbjct: 503 RVVGGFGAASGEVPWQVSLKEGSRHFCGATVVGDRWLLSAAHCFNHTKVEQVRAHLGTAS 562
Query: 78 IEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINSRVSAISLPTAPPA--A 135
+ L G+ I +++ HP YN LD D+ +++L+SP N + + LP A
Sbjct: 563 LLGLGGSPVKIGLRRVVLHPLYNPGILDFDLAVLELASPLAFNKYIQPVCLPLAIQKFPV 622
Query: 136 GTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITNNMFCVGFLEGGKDS 195
G + +ISGWGNT A P+ LQ ++ Q C Y +T+ M C GFLEG DS
Sbjct: 623 GRKCMISGWGNTQEGNATKPELLQKASVGIIDQKTCSVLYNFSLTDRMICAGFLEGKVDS 682
Query: 196 CQGDSGGPVVSNGE-----LQGIVSWGYGCAQKNRPGVYTKVYNYVDWIKDTIAA 245
CQGDSGGP+ L GIVSWG GCAQ +PGVYT++ WI + +++
Sbjct: 683 CQGDSGGPLACEEAPGVFYLAGIVSWGIGCAQVKKPGVYTRITRLKGWILEIMSS 737
Score = 156 bits (395), Expect = 1e-38
Identities = 87/232 (37%), Positives = 123/232 (53%), Gaps = 17/232 (7%)
Query: 23 KIVGGYICEENSVPYQVSLNSGY-HFCGGSLISEQWVVSAGHCYK-----SRIQVRLGEH 76
+IVGG P+Q SL HFCG ++I+ +W+VSA HC+ ++ +G
Sbjct: 202 RIVGGMEASPGEFPWQASLRENKEHFCGAAIINARWLVSAAHCFNEFQDPTKWVAYVGAT 261
Query: 77 NIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINSRVSAISLPTA----P 132
+ E + +I++HP YN+ T D D+ +++L+SP + + LP A P
Sbjct: 262 YLSGSEASTVRAQVVQIVKHPLYNADTADFDVAVLELTSPLPFGRHIQPVCLPAATHIFP 321
Query: 133 PAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITNNMFCVGFLEGG 192
P+ + LISGWG P+ LQ +L QA C + Y +T+ M C G+L+G
Sbjct: 322 PSK--KCLISGWGYLKEDFLVKPEVLQKATVELLDQALCASLYGHSLTDRMVCAGYLDGK 379
Query: 193 KDSCQGDSGGPVVSNGE-----LQGIVSWGYGCAQKNRPGVYTKVYNYVDWI 239
DSCQGDSGGP+V L GIVSWG GCA+ RPGVY +V DWI
Sbjct: 380 VDSCQGDSGGPLVCEEPSGRFFLAGIVSWGIGCAEARRPGVYARVTRLRDWI 431
Score = 147 bits (371), Expect = 8e-36
Identities = 89/231 (38%), Positives = 123/231 (53%), Gaps = 17/231 (7%)
Query: 23 KIVGGYICEENSVPYQVSL--NSGYHFCGGSLISEQWVVSAGHCYK-----SRIQVRLGE 75
+IVGG P+QVSL H CG L++E+W++SA HC+ + LG
Sbjct: 826 RIVGGSAAGRGEWPWQVSLWLRRREHRCGAVLVAERWLLSAAHCFDVYGDPKQWAAFLGT 885
Query: 76 HNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINSRVSAISLPT-AP-P 133
+ EG Q A+I +HP YN TLD D+ L++L+ P + V I LP AP P
Sbjct: 886 PFLSGAEG--QLERVARIYKHPFYNLYTLDYDVALLELAGPVRRSRLVRPICLPEPAPRP 943
Query: 134 AAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITNNMFCVGFLEGGK 193
GT +I+GWG+ + G +LQ +LS+ C YP +I++ M C GF +GG
Sbjct: 944 PDGTRCVITGWGS-VREGGSMARQLQKAAVRLLSEQTCRRFYPVQISSRMLCAGFPQGGV 1002
Query: 194 DSCQGDSGGPVV-----SNGELQGIVSWGYGCAQKNRPGVYTKVYNYVDWI 239
DSC GD+GGP+ L G+ SWGYGC + + PGVYT+V WI
Sbjct: 1003 DSCSGDAGGPLACREPSGRWVLTGVTSWGYGCGRPHFPGVYTRVAAVRGWI 1053
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.135 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,028,671
Number of Sequences: 37866
Number of extensions: 452109
Number of successful extensions: 1723
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 165
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1053
Number of HSP's gapped (non-prelim): 196
length of query: 247
length of database: 18,247,518
effective HSP length: 100
effective length of query: 147
effective length of database: 14,460,918
effective search space: 2125754946
effective search space used: 2125754946
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.