Search of human proteins with 4505701

Search of human proteins with 4505701

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4505701 pyridoxal kinase [Homo sapiens]
         (312 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4505701 pyridoxal kinase [Homo sapiens]                            624   e-179
gi|11545855 ribokinase [Homo sapiens]                                  34   0.19 
gi|23943872 small ArfGAP2 [Homo sapiens]                               33   0.42 
gi|239749961 PREDICTED: hypothetical protein LOC100129826 [Homo ...    29   4.7  
gi|239582765 ral guanine nucleotide dissociation stimulator-like...    29   4.7  
gi|239582763 ral guanine nucleotide dissociation stimulator-like...    29   4.7  
gi|84000432 hypothetical protein LOC157769 [Homo sapiens]              29   4.7  
gi|31542652 coiled-coil domain containing 94 [Homo sapiens]            29   4.7  
gi|194306651 pyruvate dehydrogenase phosphatase regulatory subun...    29   6.1  
gi|24308141 small glutamine-rich tetratricopeptide repeat (TPR)-...    28   8.0  

>gi|4505701 pyridoxal kinase [Homo sapiens]
          Length = 312

 Score =  624 bits (1610), Expect = e-179
 Identities = 312/312 (100%), Positives = 312/312 (100%)

Query: 1   MEEECRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSD 60
           MEEECRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSD
Sbjct: 1   MEEECRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSD 60

Query: 61  ELQELYEGLRLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKW 120
           ELQELYEGLRLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKW
Sbjct: 61  ELQELYEGLRLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKW 120

Query: 121 DGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGP 180
           DGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGP
Sbjct: 121 DGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGP 180

Query: 181 DTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAM 240
           DTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAM
Sbjct: 181 DTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAM 240

Query: 241 LLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRMVQSKRDI 300
           LLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRMVQSKRDI
Sbjct: 241 LLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRMVQSKRDI 300

Query: 301 EDPEIVVQATVL 312
           EDPEIVVQATVL
Sbjct: 301 EDPEIVVQATVL 312


>gi|11545855 ribokinase [Homo sapiens]
          Length = 322

 Score = 33.9 bits (76), Expect = 0.19
 Identities = 38/158 (24%), Positives = 66/158 (41%), Gaps = 20/158 (12%)

Query: 122 GEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPD 181
           G  +++ P   +     +   L+D+   N+ EAE+L+G  + S  +A     +L   G  
Sbjct: 171 GVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQ 230

Query: 182 TVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAV-FVGTGDLFAAM 240
            V+IT        G+   +VL SQ    P          +   KV AV   G GD F   
Sbjct: 231 VVIIT-------LGAEGCVVL-SQTEPEPK--------HIPTEKVKAVDTTGAGDSFVGA 274

Query: 241 LLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQA 278
           L  +   +PN   ++ E  ++  + +   ++Q A  Q+
Sbjct: 275 LAFYLAYYPN---LSLEDMLNRSNFIAAVSVQAAGTQS 309


>gi|23943872 small ArfGAP2 [Homo sapiens]
          Length = 429

 Score = 32.7 bits (73), Expect = 0.42
 Identities = 55/205 (26%), Positives = 74/205 (36%), Gaps = 42/205 (20%)

Query: 31  LGFEIDAVNSVQFSNHTGYAHWKGQVLNSDELQELYEGLRLNNMNK--YDYVLTGYTRDK 88
           LG  I  V SV     T       Q + + +   LYE        +   D  + G+ RDK
Sbjct: 58  LGVHISRVKSVNLDQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAVEGFIRDK 117

Query: 89  ----SFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDGEGSMYVPEDLL-PVYKEKVVPL 143
                ++   +DI    K+++            DKW   GS  VPE  L PV  EKV   
Sbjct: 118 YEKKKYMDRSLDINAFRKEKD------------DKWK-RGSEPVPEKKLEPVVFEKVK-- 162

Query: 144 ADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVITSS--------------D 189
                P + E   L  +   S +    VMD+L    P    I +S               
Sbjct: 163 ----MPQKKEDPQLPRKS--SPKSTAPVMDLLGLDAPVACSIANSKTSNTLEKDLDLLAS 216

Query: 190 LPSPQGSNYLIVLGSQRRRNPAGSV 214
           +PSP  S    V+GS      AGSV
Sbjct: 217 VPSPSSSGSRKVVGSMPTAGSAGSV 241


>gi|239749961 PREDICTED: hypothetical protein LOC100129826 [Homo
           sapiens]
          Length = 228

 Score = 29.3 bits (64), Expect = 4.7
 Identities = 21/78 (26%), Positives = 41/78 (52%), Gaps = 5/78 (6%)

Query: 130 EDLLPVYKEKVVPL-ADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVITSS 188
           E +LP+  E+V+P+ ++ + P   E  L +G    S++      + +   G + V+ T S
Sbjct: 36  EQILPMPSEQVLPMGSEHVLPTGSEQVLPTG----SEQVLPTGSEHVLPTGSEQVLPTGS 91

Query: 189 DLPSPQGSNYLIVLGSQR 206
           D   P GS +++  GS++
Sbjct: 92  DHVLPTGSEHVLSTGSEQ 109


>gi|239582765 ral guanine nucleotide dissociation stimulator-like 3
           isoform 1 [Homo sapiens]
          Length = 716

 Score = 29.3 bits (64), Expect = 4.7
 Identities = 27/81 (33%), Positives = 40/81 (49%), Gaps = 9/81 (11%)

Query: 179 GPDTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMER-IRMDIRKVDAVFVGTGDLF 237
           GP T +  S DLPSP+   + + LGS R   PA      R IR+ I          G+L+
Sbjct: 584 GPSTKLPLSLDLPSPR--PFALPLGSPRIPLPAQQSSEARVIRVSIDN------DHGNLY 635

Query: 238 AAMLLAWTHKHPNNLKVACEK 258
            ++LL    K P+ ++ A +K
Sbjct: 636 RSILLTSQDKAPSVVRRALQK 656


>gi|239582763 ral guanine nucleotide dissociation stimulator-like 3
           isoform 2 [Homo sapiens]
          Length = 710

 Score = 29.3 bits (64), Expect = 4.7
 Identities = 27/81 (33%), Positives = 40/81 (49%), Gaps = 9/81 (11%)

Query: 179 GPDTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMER-IRMDIRKVDAVFVGTGDLF 237
           GP T +  S DLPSP+   + + LGS R   PA      R IR+ I          G+L+
Sbjct: 578 GPSTKLPLSLDLPSPR--PFALPLGSPRIPLPAQQSSEARVIRVSIDN------DHGNLY 629

Query: 238 AAMLLAWTHKHPNNLKVACEK 258
            ++LL    K P+ ++ A +K
Sbjct: 630 RSILLTSQDKAPSVVRRALQK 650


>gi|84000432 hypothetical protein LOC157769 [Homo sapiens]
          Length = 838

 Score = 29.3 bits (64), Expect = 4.7
 Identities = 15/41 (36%), Positives = 24/41 (58%), Gaps = 1/41 (2%)

Query: 30  VLGFEIDAV-NSVQFSNHTGYAHWKGQVLNSDELQELYEGL 69
           VL  ++  V N+V      G+AH KGQV+N D+L   ++ +
Sbjct: 274 VLEIDLSLVKNAVSMYCRLGFAHKKGQVINLDQLHSSWKNV 314


>gi|31542652 coiled-coil domain containing 94 [Homo sapiens]
          Length = 323

 Score = 29.3 bits (64), Expect = 4.7
 Identities = 25/87 (28%), Positives = 40/87 (45%), Gaps = 6/87 (6%)

Query: 28  LQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSDE---LQELYEGLRLNNMNKYDYVLTGY 84
           L  + F+ D  N+     H    +++ + L  +E   +Q+  E   LNN  K   VL   
Sbjct: 84  LAEITFKTDPENTDYTMEHGATRNFQAEKLLEEEEKRVQKEREDEELNNPMK---VLENR 140

Query: 85  TRDKSFLAMVVDIVQELKQQNPRLVYV 111
           T+D      V++ +QELK  N R  +V
Sbjct: 141 TKDSKLEMEVLENLQELKDLNQRQAHV 167


>gi|194306651 pyruvate dehydrogenase phosphatase regulatory subunit
           [Homo sapiens]
          Length = 879

 Score = 28.9 bits (63), Expect = 6.1
 Identities = 31/107 (28%), Positives = 46/107 (42%), Gaps = 22/107 (20%)

Query: 80  VLTGYTRDKS-FLAMVVDIVQELKQQNPRLVYVCDP--VLGDKWDGE-----------GS 125
           + TGYTR  S FLA   D +  LK+ N  L  +  P  ++  K   E           G+
Sbjct: 118 IQTGYTRTGSIFLAQTQDRLISLKRINAGLNVIGIPSEIISPKKVAELHHLLNVHDLVGA 177

Query: 126 MYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVM 172
           M+VPED +    +  + LA   + N        G +I+ +   L VM
Sbjct: 178 MHVPEDAVVSSADVALALASAASQN--------GVQIYDRTSVLHVM 216


>gi|24308141 small glutamine-rich tetratricopeptide repeat
           (TPR)-containing, beta [Homo sapiens]
          Length = 304

 Score = 28.5 bits (62), Expect = 8.0
 Identities = 14/65 (21%), Positives = 30/65 (46%)

Query: 45  NHTGYAHWKGQVLNSDELQELYEGLRLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQ 104
           N+  +      ++ + ++Q+L  G+  N +      + G T   S +       Q+++QQ
Sbjct: 220 NNPAFISMAASLMQNPQVQQLMSGMMTNAIGGPAAGVGGLTDLSSLIQAGQQFAQQIQQQ 279

Query: 105 NPRLV 109
           NP L+
Sbjct: 280 NPELI 284


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,441,048
Number of Sequences: 37866
Number of extensions: 492923
Number of successful extensions: 1102
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1090
Number of HSP's gapped (non-prelim): 15
length of query: 312
length of database: 18,247,518
effective HSP length: 102
effective length of query: 210
effective length of database: 14,385,186
effective search space: 3020889060
effective search space used: 3020889060
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.