Search of human proteins with 4505595

Search of human proteins with 4505595

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4505595 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 2 [Homo sapiens]
         (415 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|219689110 serine (or cysteine) proteinase inhibitor, clade B ...   831   0.0  
gi|4505595 serine (or cysteine) proteinase inhibitor, clade B (o...   831   0.0  
gi|13489087 serine (or cysteine) proteinase inhibitor, clade B (...   361   e-100
gi|4826902 serine (or cysteine) proteinase inhibitor, clade B (o...   355   5e-98
gi|41152086 serine (or cysteine) proteinase inhibitor, clade B (...   343   2e-94
gi|38504669 serine (or cysteine) proteinase inhibitor, clade B (...   337   9e-93
gi|38504673 serine (or cysteine) proteinase inhibitor, clade B (...   337   9e-93
gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo s...   331   8e-91
gi|28076869 serine (or cysteine) proteinase inhibitor, clade B (...   305   5e-83
gi|5902072 serine (or cysteine) proteinase inhibitor, clade B (o...   303   1e-82
gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Hom...   291   6e-79
gi|17998551 serine (or cysteine) proteinase inhibitor, clade B (...   288   6e-78
gi|8393956 serine (or cysteine) proteinase inhibitor, clade B (o...   284   9e-77
gi|92859634 serine (or cysteine) proteinase inhibitor, clade B (...   252   5e-67
gi|4505149 serine (or cysteine) proteinase inhibitor, clade B (o...   252   5e-67
gi|167860126 serine (or cysteine) proteinase inhibitor, clade B ...   240   2e-63
gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo s...   212   6e-55
gi|73623033 serine (or cysteine) proteinase inhibitor, clade B (...   197   1e-50
gi|170295807 neuroserpin precursor [Homo sapiens]                     195   6e-50
gi|4826904 neuroserpin precursor [Homo sapiens]                       195   6e-50
gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member...   189   4e-48
gi|110225347 serine (or cysteine) proteinase inhibitor, clade A ...   186   3e-47
gi|50659080 serpin peptidase inhibitor, clade A, member 3 precur...   183   3e-46
gi|73858566 heparin cofactor II precursor [Homo sapiens]              180   2e-45
gi|194018472 serine (or cysteine) proteinase inhibitor, clade A ...   179   5e-45
gi|189163542 serine proteinase inhibitor, clade A, member 1 [Hom...   174   1e-43
gi|189163540 serine proteinase inhibitor, clade A, member 1 [Hom...   174   1e-43
gi|189163538 serine proteinase inhibitor, clade A, member 1 [Hom...   174   1e-43
gi|189163536 serine proteinase inhibitor, clade A, member 1 [Hom...   174   1e-43
gi|189163534 serine proteinase inhibitor, clade A, member 1 [Hom...   174   1e-43

>gi|219689110 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 2 [Homo sapiens]
          Length = 415

 Score =  831 bits (2147), Expect = 0.0
 Identities = 415/415 (100%), Positives = 415/415 (100%)

Query: 1   MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
           MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF
Sbjct: 1   MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60

Query: 61  NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
           NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN
Sbjct: 61  NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120

Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
           YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK
Sbjct: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180

Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
           IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK
Sbjct: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240

Query: 241 LNIGYIEDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKM 300
           LNIGYIEDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKM
Sbjct: 241 LNIGYIEDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKM 300

Query: 301 AEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMV 360
           AEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMV
Sbjct: 301 AEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMV 360

Query: 361 DVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
           DVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP
Sbjct: 361 DVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415


>gi|4505595 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 2 [Homo sapiens]
          Length = 415

 Score =  831 bits (2147), Expect = 0.0
 Identities = 415/415 (100%), Positives = 415/415 (100%)

Query: 1   MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
           MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF
Sbjct: 1   MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60

Query: 61  NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
           NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN
Sbjct: 61  NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120

Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
           YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK
Sbjct: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180

Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
           IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK
Sbjct: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240

Query: 241 LNIGYIEDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKM 300
           LNIGYIEDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKM
Sbjct: 241 LNIGYIEDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKM 300

Query: 301 AEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMV 360
           AEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMV
Sbjct: 301 AEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMV 360

Query: 361 DVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
           DVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP
Sbjct: 361 DVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415


>gi|13489087 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 1 [Homo sapiens]
          Length = 379

 Score =  361 bits (927), Expect = e-100
 Identities = 190/416 (45%), Positives = 263/416 (63%), Gaps = 38/416 (9%)

Query: 1   MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
           ME L  ANT FAL+LF  L++ +P  N+F+SP+SISS MAMV++G+RG+T  Q++K   F
Sbjct: 1   MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF 60

Query: 61  NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
           N V                                     +++HS F+SL++ IN    +
Sbjct: 61  NTV-------------------------------------EEVHSRFQSLNADINKRGAS 83

Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
           Y+L+  N+L+GEK+ +F  E++   QK Y ++  +VDF   +E+ARK IN WVK QT+GK
Sbjct: 84  YILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVDFQHASEDARKTINQWVKGQTEGK 143

Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
           IP LL  G VD  T++VLVNA+YFKG WK  F K+     PFR+N   R  V+MMY ++K
Sbjct: 144 IPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEATTNAPFRLNKKDRKTVKMMYQKKK 203

Query: 241 LNIGYIEDLKAQILELPYAG-DVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299
              GYIEDLK ++LELPY G ++SM +LLPD+I D STGL+ +E ++T +KL++WT  + 
Sbjct: 204 FAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDESTGLKKIEEQLTLEKLHEWTKPEN 263

Query: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359
           +   EV V +P+FKLEE Y L S L  +G++D FN  +A+ SGMS   D+F+S++ H++ 
Sbjct: 264 LDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSSKADLSGMSGARDIFISKIVHKSF 323

Query: 360 VDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
           V+VNEEGTEAAA T G+ T         F ADHPFLF I H  +  ILF GRFSSP
Sbjct: 324 VEVNEEGTEAAAATAGIATFCMLMPEENFTADHPFLFFIRHNSSGSILFLGRFSSP 379


>gi|4826902 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 10 [Homo sapiens]
          Length = 397

 Score =  355 bits (910), Expect = 5e-98
 Identities = 190/416 (45%), Positives = 278/416 (66%), Gaps = 20/416 (4%)

Query: 1   MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
           M+ L  +   FAL L K LA+++  +N+F S WSIS+++ +VY+G++G+T  QMA+VLQF
Sbjct: 1   MDSLATSINQFALELSKKLAESAQGKNIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQF 60

Query: 61  NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
           N    +      PE+       ++ +K  +         +++IHS F++L S I     +
Sbjct: 61  NR---DQGVKCDPES-------EKKRKMEF-----NLSNSEEIHSDFQTLISEILKPNDD 105

Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
           YLL++ N ++GEK+ +F  +Y+   + Y+ +EPQ V+F+E +++ RK INSWV+ QT+GK
Sbjct: 106 YLLKTANAIYGEKTYAFHNKYLEDMKTYFGAEPQPVNFVEASDQIRKDINSWVERQTEGK 165

Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
           I NLLP+ SVD  TRM+LVNA+YFKG W+  F  +     PFR+N     PVQMM++++K
Sbjct: 166 IQNLLPDDSVDSTTRMILVNALYFKGIWEHQFLVQNTTEKPFRINETTSKPVQMMFMKKK 225

Query: 241 LNIGYIEDLKAQILELPYAG-DVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299
           L+I +IE  KA  L+L Y   D+S+ +LLP++I     GLE LE  ITY+KLN+WTS D 
Sbjct: 226 LHIFHIEKPKAVGLQLYYKSRDLSLLILLPEDI----NGLEQLEKAITYEKLNEWTSADM 281

Query: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359
           M   EV++++P+FKLE+ Y+L+S L SMGM DAF++ +A+FSGMS   +LFLS VFH+A 
Sbjct: 282 MELYEVQLHLPKFKLEDSYDLKSTLSSMGMSDAFSQSKADFSGMSSARNLFLSNVFHKAF 341

Query: 360 VDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
           V++NE+GTEAAAG+G  +  R      +F A+HPFLF I H  TN ILF+GR  SP
Sbjct: 342 VEINEQGTEAAAGSGSEIDIRIRVPSIEFNANHPFLFFIRHNKTNTILFYGRLCSP 397


>gi|41152086 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 6 [Homo sapiens]
          Length = 376

 Score =  343 bits (880), Expect = 2e-94
 Identities = 189/416 (45%), Positives = 256/416 (61%), Gaps = 41/416 (9%)

Query: 1   MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
           M+ L  AN  FALNL K L K + ++N+F SP S+S  +AMVYMG++G+T  QMA++L F
Sbjct: 1   MDVLAEANGTFALNLLKTLGKDN-SKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF 59

Query: 61  NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
           N+ G                                      IH  F+SL + +N +   
Sbjct: 60  NKSGGGG----------------------------------DIHQGFQSLLTEVNKTGTQ 85

Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
           YLL   N+LFGEKS  F   +   CQK+Y +E + +DF+   E++RK IN+WV  +T+GK
Sbjct: 86  YLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISAVEKSRKHINTWVAEKTEGK 145

Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
           I  LL  GSVD  TR+VLVNAVYF+G W   F+K+      F+V+  +  PVQMM+ +  
Sbjct: 146 IAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEERLFKVSKNEEKPVQMMFKQST 205

Query: 241 LNIGYIEDLKAQILELPYAG-DVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299
               YI ++  QIL LPY G +++M ++LPDE  D+ T    +E E+TY+K  +WT  D 
Sbjct: 206 FKKTYIGEIFTQILVLPYVGKELNMIIMLPDETTDLRT----VEKELTYEKFVEWTRLDM 261

Query: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359
           M E+EVEV +P+FKLEE Y++ S+LR++GM DAF  G+A+FSGMS+  DL LS+V H++ 
Sbjct: 262 MDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADFSGMSQ-TDLSLSKVVHKSF 320

Query: 360 VDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
           V+VNEEGTEAAA T  +M  R     P+F ADHPFLF I H  TN ILF GRFSSP
Sbjct: 321 VEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFFIQHSKTNGILFCGRFSSP 376


>gi|38504669 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 8 isoform a [Homo sapiens]
          Length = 374

 Score =  337 bits (865), Expect = 9e-93
 Identities = 180/416 (43%), Positives = 254/416 (61%), Gaps = 43/416 (10%)

Query: 1   MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
           M+DLC AN  FA++LFK L +   ++N+F SP SISS +AMV+MG++GST  QM++ L  
Sbjct: 1   MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60

Query: 61  NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
            + G                                      IH  F+SL S +N +   
Sbjct: 61  YKDG-------------------------------------DIHRGFQSLLSEVNRTGTQ 83

Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
           YLL + N+LFGEK+  F  ++   CQK+Y +E + + F E  EE RK IN WV  +T+GK
Sbjct: 84  YLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGK 143

Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
           I  +L  G+VD  T++VLVNA+YFKGKW   F++K      F+ N  ++T VQMM+   K
Sbjct: 144 ISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFKTNEEKKT-VQMMFKEAK 202

Query: 241 LNIGYIEDLKAQILELPYAGD-VSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299
             +GY +++  Q+LELPY  + +SM +LLPD+    +T L ++E  +TY+K   WT+ +K
Sbjct: 203 FKMGYADEVHTQVLELPYVEEELSMVILLPDD----NTDLAVVEKALTYEKFKAWTNSEK 258

Query: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359
           + + +V+V++P+ KLEE Y+L   LR +GM DAF++ +A+FSGMS   ++ LS+V H+  
Sbjct: 259 LTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKCF 318

Query: 360 VDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
           V+VNEEGTEAAA T  V   R     P+F ADHPFLF I H  TNCILF GRFSSP
Sbjct: 319 VEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 374


>gi|38504673 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 8 isoform a [Homo sapiens]
          Length = 374

 Score =  337 bits (865), Expect = 9e-93
 Identities = 180/416 (43%), Positives = 254/416 (61%), Gaps = 43/416 (10%)

Query: 1   MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
           M+DLC AN  FA++LFK L +   ++N+F SP SISS +AMV+MG++GST  QM++ L  
Sbjct: 1   MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60

Query: 61  NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
            + G                                      IH  F+SL S +N +   
Sbjct: 61  YKDG-------------------------------------DIHRGFQSLLSEVNRTGTQ 83

Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
           YLL + N+LFGEK+  F  ++   CQK+Y +E + + F E  EE RK IN WV  +T+GK
Sbjct: 84  YLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGK 143

Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
           I  +L  G+VD  T++VLVNA+YFKGKW   F++K      F+ N  ++T VQMM+   K
Sbjct: 144 ISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFKTNEEKKT-VQMMFKEAK 202

Query: 241 LNIGYIEDLKAQILELPYAGD-VSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299
             +GY +++  Q+LELPY  + +SM +LLPD+    +T L ++E  +TY+K   WT+ +K
Sbjct: 203 FKMGYADEVHTQVLELPYVEEELSMVILLPDD----NTDLAVVEKALTYEKFKAWTNSEK 258

Query: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359
           + + +V+V++P+ KLEE Y+L   LR +GM DAF++ +A+FSGMS   ++ LS+V H+  
Sbjct: 259 LTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKCF 318

Query: 360 VDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
           V+VNEEGTEAAA T  V   R     P+F ADHPFLF I H  TNCILF GRFSSP
Sbjct: 319 VEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 374


>gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo
           sapiens]
          Length = 376

 Score =  331 bits (848), Expect = 8e-91
 Identities = 175/417 (41%), Positives = 253/417 (60%), Gaps = 43/417 (10%)

Query: 1   MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
           ME L  A+  FA+ L K L + +P+ N+F SP SISS +AMV +G++G+T  QMA+ L  
Sbjct: 1   METLSNASGTFAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSL 60

Query: 61  NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
           N                                       + IH +F+SL + +N +   
Sbjct: 61  N-------------------------------------TEEDIHRAFQSLLTEVNKAGTQ 83

Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
           YLL + N+LFGEK+  F   +   C ++Y +E + + F+  AEE+RK IN+WV  +T+GK
Sbjct: 84  YLLRTANRLFGEKTCQFLSTFKESCLQFYHAELKELSFIRAAEESRKHINTWVSKKTEGK 143

Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
           I  LLP  S+D +TR+VLVNA+YFKGKW  PF++      PF++N  ++ PVQMMY    
Sbjct: 144 IEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYTREMPFKINQEEQRPVQMMYQEAT 203

Query: 241 LNIGYIEDLKAQILELPYA-GDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299
             + ++ +++AQ+LELPYA  ++S+ +LLPD+  ++ST    +E  +T++KL  WT  D 
Sbjct: 204 FKLAHVGEVRAQLLELPYARKELSLLVLLPDDGVELST----VEKSLTFEKLTAWTKPDC 259

Query: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359
           M   EVEV +P+FKL+E Y++ S+LR +G+ DAF +G+A+ S MS   DL LS+  H++ 
Sbjct: 260 MKSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQGKADLSAMSAERDLCLSKFVHKSF 319

Query: 360 VDVNEEGTEAAAGTG-GVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
           V+VNEEGTEAAA +   V+       GP+F ADHPFLF I H   N ILF GRFSSP
Sbjct: 320 VEVNEEGTEAAAASSCFVVAECCMESGPRFCADHPFLFFIRHNRANSILFCGRFSSP 376


>gi|28076869 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 4 [Homo sapiens]
          Length = 390

 Score =  305 bits (781), Expect = 5e-83
 Identities = 172/417 (41%), Positives = 246/417 (58%), Gaps = 29/417 (6%)

Query: 1   MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
           M  L  ANT F  +LF+   K S   N+F SP SI+S + MV +G++ +T  Q++KVL F
Sbjct: 1   MNSLSEANTKFMFDLFQQFRK-SKENNIFYSPISITSALGMVLLGAKDNTAQQISKVLHF 59

Query: 61  NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
           ++V  N                          A      +  +H  F+ L +  N ST  
Sbjct: 60  DQVTENTTEKA---------------------ATYHVDRSGNVHHQFQKLLTEFNKSTDA 98

Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
           Y L+  NKLFGEK+  F +EY+   +K+Y +  ++ DF    EE+RKKINSWV++QT  K
Sbjct: 99  YELKIANKLFGEKTYQFLQEYLDAIKKFYQTSVESTDFANAPEESRKKINSWVESQTNEK 158

Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
           I NL P+G++  DT +VLVNA+YFKG+W+  F+K+      F  N      VQMM     
Sbjct: 159 IKNLFPDGTIGNDTTLVLVNAIYFKGQWENKFKKENTKEEKFWPNKNTYKSVQMMRQYNS 218

Query: 241 LNIGYIEDLKAQILELPYAG-DVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299
            N   +ED++A++LE+PY G D+SM +LLP+EI     GL+ LE ++T +KL +WTS   
Sbjct: 219 FNFALLEDVQAKVLEIPYKGKDLSMIVLLPNEI----DGLQKLEEKLTAEKLMEWTSLQN 274

Query: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359
           M E  V++++P+FK+EE Y+L+  LR+MGM + FN G A+ SGM+  + L +S+V H+A 
Sbjct: 275 MRETCVDLHLPRFKMEESYDLKDTLRTMGMVNIFN-GDADLSGMTWSHGLSVSKVLHKAF 333

Query: 360 VDVNEEGTEAAAGTGGVMTGRTGHG-GPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
           V+V EEG EAAA T  V+   +      +F  +HPFLF I    TN ILF+GRFSSP
Sbjct: 334 VEVTEEGVEAAAATAVVVVELSSPSTNEEFCCNHPFLFFIRQNKTNSILFYGRFSSP 390


>gi|5902072 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 3 [Homo sapiens]
          Length = 390

 Score =  303 bits (777), Expect = 1e-82
 Identities = 174/417 (41%), Positives = 244/417 (58%), Gaps = 29/417 (6%)

Query: 1   MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
           M  L  ANT F  +LF+   K S   N+F SP SI+S + MV +G++ +T  Q+ KVL F
Sbjct: 1   MNSLSEANTKFMFDLFQQFRK-SKENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHF 59

Query: 61  NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
           ++V  N                          A      +  +H  F+ L +  N ST  
Sbjct: 60  DQVTENTTGKA---------------------ATYHVDRSGNVHHQFQKLLTEFNKSTDA 98

Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
           Y L+  NKLFGEK+  F +EY+   +K+Y +  ++VDF    EE+RKKINSWV++QT  K
Sbjct: 99  YELKIANKLFGEKTYLFLQEYLDAIKKFYQTSVESVDFANAPEESRKKINSWVESQTNEK 158

Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
           I NL+PEG++  +T +VLVNA+YFKG+W+  F K+      F  N      +QMM     
Sbjct: 159 IKNLIPEGNIGSNTTLVLVNAIYFKGQWEKKFNKEDTKEEKFWPNKNTYKSIQMMRQYTS 218

Query: 241 LNIGYIEDLKAQILELPYAG-DVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299
            +   +ED++A++LE+PY G D+SM +LLP+EI     GL+ LE ++T +KL +WTS   
Sbjct: 219 FHFASLEDVQAKVLEIPYKGKDLSMIVLLPNEI----DGLQKLEEKLTAEKLMEWTSLQN 274

Query: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359
           M E  V++++P+FK+EE Y+L+  LR+MGM D FN G A+ SGM+    L LS V H+A 
Sbjct: 275 MRETRVDLHLPRFKVEESYDLKDTLRTMGMVDIFN-GDADLSGMTGSRGLVLSGVLHKAF 333

Query: 360 VDVNEEGTEAAAGTGGVMTGRTGHG-GPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
           V+V EEG EAAA T  V  G +      +F  +HPFLF I    TN ILF+GRFSSP
Sbjct: 334 VEVTEEGAEAAAATAVVGFGSSPTSTNEEFHCNHPFLFFIRQNKTNSILFYGRFSSP 390


>gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Homo
           sapiens]
          Length = 392

 Score =  291 bits (746), Expect = 6e-79
 Identities = 161/416 (38%), Positives = 247/416 (59%), Gaps = 25/416 (6%)

Query: 1   MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
           M  L  AN  F L++FK L   +   N+F S  S+   ++MV +G+RG TE+Q+ KVL F
Sbjct: 1   MGSLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHF 60

Query: 61  NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
           +    + V  + P                + D+   +QA  +IHS F    S IN    N
Sbjct: 61  S----HTVDSLKP---------------GFKDSPKCSQAG-RIHSEFGVEFSQINQPDSN 100

Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
             L   N+L+G K+ +F ++Y+   +K+Y +  Q VDF +  EE RK IN+WV+ +T GK
Sbjct: 101 CTLSIANRLYGTKTMAFHQQYLSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGK 160

Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
           + NL  + ++D  + MVLVNA+YFKG+W+  F+ +     PF+++  +   V+MMY    
Sbjct: 161 VANLFGKSTIDPSSVMVLVNAIYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGT 220

Query: 241 LNIGYIEDLKAQILELPYAGD-VSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299
             + ++++ + Q+LELPY  + +SM +LLP  IA+    L+ +E ++     ++WTS   
Sbjct: 221 FKLAFVKEPQMQVLELPYVNNKLSMIILLPVGIAN----LKQIEKQLNSGTFHEWTSSSN 276

Query: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359
           M E EVEV++P+FKLE  YEL S+L+S+G+ D FN+ +A+ SGMS    L+LS+  H++ 
Sbjct: 277 MMEREVEVHLPRFKLETKYELNSLLKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSY 336

Query: 360 VDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
           +DV+EEGTEAAA TG  +  ++     QF A+HPFLF I H  TN ILF G+ +SP
Sbjct: 337 LDVSEEGTEAAAATGDSIAVKSLPMRAQFKANHPFLFFIRHTHTNTILFCGKLASP 392


>gi|17998551 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 12 [Homo sapiens]
          Length = 405

 Score =  288 bits (737), Expect = 6e-78
 Identities = 159/416 (38%), Positives = 251/416 (60%), Gaps = 12/416 (2%)

Query: 1   MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
           M+ L  ANT F  +LF+ + K    +N+F SP S+S+ + MV +G+R  +  Q+ +VL F
Sbjct: 1   MDSLVTANTKFCFDLFQEIGKDDRHKNIFFSPLSLSAALGMVRLGARSDSAHQIDEVLHF 60

Query: 61  NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
           NE   N      P     C    + + GS  +       +  +   F  L S ++    +
Sbjct: 61  NEFSQNESKEPDP-----CLKSNKQKAGSLNNE------SGLVSCYFGQLLSKLDRIKTD 109

Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
           Y L   N+L+GE+     +EY+    ++Y +  ++VDF +  E++R++IN WV+ Q++GK
Sbjct: 110 YTLSIANRLYGEQEFPICQEYLDGVIQFYHTTIESVDFQKNPEKSRQEINFWVECQSQGK 169

Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
           I  L  + +++ +T +VLVNAVYFK KW+T F+ +     PF +N+ +   V+MM  +  
Sbjct: 170 IKELFSKDAINAETVLVLVNAVYFKAKWETYFDHENTVDAPFCLNANENKSVKMMTQKGL 229

Query: 241 LNIGYIEDLKAQILELPYA-GDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299
             IG+IE++KAQILE+ Y  G +SMF+LLP    D   GLE LE +ITY+K+  W+S + 
Sbjct: 230 YRIGFIEEVKAQILEMRYTKGKLSMFVLLPSHSKDNLKGLEELERKITYEKMVAWSSSEN 289

Query: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359
           M+E+ V +  P+F LE+ Y+L SIL+ MG+ D F++ RA+ +G+S   +L+LS++ H+  
Sbjct: 290 MSEESVVLSFPRFTLEDSYDLNSILQDMGITDIFDETRADLTGISPSPNLYLSKIIHKTF 349

Query: 360 VDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
           V+V+E GT+AAA TG V++ R+     +F A+HPFLF I H  T  ILF+GR  SP
Sbjct: 350 VEVDENGTQAAAATGAVVSERSLRSWVEFNANHPFLFFIRHNKTQTILFYGRVCSP 405


>gi|8393956 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 13 [Homo sapiens]
          Length = 391

 Score =  284 bits (727), Expect = 9e-77
 Identities = 161/416 (38%), Positives = 246/416 (59%), Gaps = 26/416 (6%)

Query: 1   MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
           M+ L   +T    +LFK L K +   N+F SP  I + + MV +G+RG+T  Q+ +V   
Sbjct: 1   MDSLGAVSTRLGFDLFKELKKTNDG-NIFFSPVGILTAIGMVLLGTRGATASQLEEVFH- 58

Query: 61  NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
                        E  T    ++  +K    + I   +A   +H  F+   + I+  T +
Sbjct: 59  ------------SEKETKSSRIKAEEK----EVIENTEA---VHQQFQKFLTEISKLTND 99

Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
           Y L   N+LFGEK+  F ++Y+   +KYY +  + VDF+  A+E+RKKINSWV+++T  K
Sbjct: 100 YELNITNRLFGEKTYLFLQKYLDYVEKYYHASLEPVDFVNAADESRKKINSWVESKTNEK 159

Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
           I +L P+GS+   T++VLVN VYFKG+W   F+K+      F +N +    VQMM     
Sbjct: 160 IKDLFPDGSISSSTKLVLVNMVYFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHS 219

Query: 241 LNIGYIEDLKAQILELPYA-GDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299
            +  ++EDL+A+IL +PY   D+SMF+LLP++I     GLE +  +I+ +KL +WTS   
Sbjct: 220 FSFTFLEDLQAKILGIPYKNNDLSMFVLLPNDI----DGLEKIIDKISPEKLVEWTSPGH 275

Query: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359
           M E +V +++P+F++E+ Y+L ++L +MGM DAF++ +A++SGMS  + L+  +  H + 
Sbjct: 276 MEERKVNLHLPRFEVEDGYDLEAVLAAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSF 335

Query: 360 VDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
           V V EEGTEAAA TG   T  +  G      +HPFLF I H  +N ILFFGRFSSP
Sbjct: 336 VAVTEEGTEAAAATGIGFTVTSAPGHENVHCNHPFLFFIRHNESNSILFFGRFSSP 391


>gi|92859634 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 7 [Homo sapiens]
          Length = 380

 Score =  252 bits (643), Expect = 5e-67
 Identities = 143/415 (34%), Positives = 225/415 (54%), Gaps = 35/415 (8%)

Query: 1   MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
           M  L  AN  F  NLF+ +       N+F S  S+ + +A+V +G++  +  Q+ K+L  
Sbjct: 1   MASLAAANAEFCFNLFREMDDNQGNGNVFFSSLSLFAALALVRLGAQDDSLSQIDKLLHV 60

Query: 61  NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
           N               T+ G+               + +   + S  + + S INAS  +
Sbjct: 61  N---------------TASGYGNS------------SNSQSGLQSQLKRVFSDINASHKD 93

Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
           Y L  VN LF EK   F ++YI   +K Y ++ + VDF    E+ R+ IN WV+ +T GK
Sbjct: 94  YDLSIVNGLFAEKVYGFHKDYIECAEKLYDAKVERVDFTNHLEDTRRNINKWVENETHGK 153

Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
           I N++ EG +     MVLVNAVYFKGKW++ F K       F+        V MM+   K
Sbjct: 154 IKNVIGEGGISSSAVMVLVNAVYFKGKWQSAFTKSETINCHFKSPKCSGKAVAMMHQERK 213

Query: 241 LNIGYIEDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKM 300
            N+  IED   +ILEL Y G ++M++LLP+        L  +E+++T+  L +WT+  +M
Sbjct: 214 FNLSVIEDPSMKILELRYNGGINMYVLLPE------NDLSEIENKLTFQNLMEWTNPRRM 267

Query: 301 AEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMV 360
               VEV+ PQFK+E++YE++  LR++G++D F++ +A+ SG++    L++S + H++ +
Sbjct: 268 TSKYVEVFFPQFKIEKNYEMKQYLRALGLKDIFDESKADLSGIASGGRLYISRMMHKSYI 327

Query: 361 DVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
           +V EEGTEA A TG  +  +       F ADHPFLF+I  +  + ILF G+ S P
Sbjct: 328 EVTEEGTEATAATGSNIVEKQLPQSTLFRADHPFLFVI--RKDDIILFSGKVSCP 380


>gi|4505149 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 7 [Homo sapiens]
          Length = 380

 Score =  252 bits (643), Expect = 5e-67
 Identities = 143/415 (34%), Positives = 225/415 (54%), Gaps = 35/415 (8%)

Query: 1   MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
           M  L  AN  F  NLF+ +       N+F S  S+ + +A+V +G++  +  Q+ K+L  
Sbjct: 1   MASLAAANAEFCFNLFREMDDNQGNGNVFFSSLSLFAALALVRLGAQDDSLSQIDKLLHV 60

Query: 61  NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
           N               T+ G+               + +   + S  + + S INAS  +
Sbjct: 61  N---------------TASGYGNS------------SNSQSGLQSQLKRVFSDINASHKD 93

Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
           Y L  VN LF EK   F ++YI   +K Y ++ + VDF    E+ R+ IN WV+ +T GK
Sbjct: 94  YDLSIVNGLFAEKVYGFHKDYIECAEKLYDAKVERVDFTNHLEDTRRNINKWVENETHGK 153

Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
           I N++ EG +     MVLVNAVYFKGKW++ F K       F+        V MM+   K
Sbjct: 154 IKNVIGEGGISSSAVMVLVNAVYFKGKWQSAFTKSETINCHFKSPKCSGKAVAMMHQERK 213

Query: 241 LNIGYIEDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKM 300
            N+  IED   +ILEL Y G ++M++LLP+        L  +E+++T+  L +WT+  +M
Sbjct: 214 FNLSVIEDPSMKILELRYNGGINMYVLLPE------NDLSEIENKLTFQNLMEWTNPRRM 267

Query: 301 AEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMV 360
               VEV+ PQFK+E++YE++  LR++G++D F++ +A+ SG++    L++S + H++ +
Sbjct: 268 TSKYVEVFFPQFKIEKNYEMKQYLRALGLKDIFDESKADLSGIASGGRLYISRMMHKSYI 327

Query: 361 DVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
           +V EEGTEA A TG  +  +       F ADHPFLF+I  +  + ILF G+ S P
Sbjct: 328 EVTEEGTEATAATGSNIVEKQLPQSTLFRADHPFLFVI--RKDDIILFSGKVSCP 380


>gi|167860126 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 5 [Homo sapiens]
          Length = 375

 Score =  240 bits (612), Expect = 2e-63
 Identities = 130/416 (31%), Positives = 230/416 (55%), Gaps = 42/416 (10%)

Query: 1   MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
           M+ L +AN+ FA++LFK L +  P  N+  SP  +S+++++  +G++G T +++ +VL F
Sbjct: 1   MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHF 60

Query: 61  NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
             V                                       +   F++++S +N  +  
Sbjct: 61  ENV-------------------------------------KDVPFGFQTVTSDVNKLSSF 83

Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
           Y L+ + +L+ +KS +   E+I   ++ Y+ E + VDF +  EE + +IN+ +K  T G 
Sbjct: 84  YSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFKDKLEETKGQINNSIKDLTDGH 143

Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
             N+L + SV+  T++++VNA YF GKW   F +      PFRVN     PVQMM +   
Sbjct: 144 FENILADNSVNDQTKILVVNAAYFVGKWMKKFSESETKECPFRVNKTDTKPVQMMNMEAT 203

Query: 241 LNIGYIEDLKAQILELPYAG-DVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299
             +G I+ +  +I+ELP+    +SMF+LLP ++ D STGLE +E ++  + L++WT+   
Sbjct: 204 FCMGNIDSINCKIIELPFQNKHLSMFILLPKDVEDESTGLEKIEKQLNSESLSQWTNPST 263

Query: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359
           MA  +V++ IP+FK+E+  + ++ L ++G++  F++  ++FSGMSE   + LS V H+  
Sbjct: 264 MANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSEDTSDFSGMSETKGVALSNVIHKVC 323

Query: 360 VDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
           +++ E+G ++    G     R      +  ADHPF+++I H  T  I+FFG+F SP
Sbjct: 324 LEITEDGGDSIEVPG----ARILQHKDELNADHPFIYIIRHNKTRNIIFFGKFCSP 375


>gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo
           sapiens]
          Length = 464

 Score =  212 bits (539), Expect = 6e-55
 Identities = 134/419 (31%), Positives = 222/419 (52%), Gaps = 45/419 (10%)

Query: 3   DLCVANTLFALNLFKHLAKA-SPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFN 61
           +L  AN+ FA   ++HLA + +   N+FLSP SIS+  AM  +G+   T  Q+ +V +F+
Sbjct: 82  ELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFD 141

Query: 62  EVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAI-NASTGN 120
            +                                  + +D+IH  F  L+  +   +  +
Sbjct: 142 TISE--------------------------------KTSDQIHFFFAKLNCRLYRKANKS 169

Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
             L S N+LFG+KS +F E Y  + +  Y ++ Q +DF E AE++R  IN WV  +T+G+
Sbjct: 170 SKLVSANRLFGDKSLTFNETYQDISELVYGAKLQPLDFKENAEQSRAAINKWVSNKTEGR 229

Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
           I +++P  +++  T +VLVN +YFKG WK+ F  +      F     +     MMY   K
Sbjct: 230 ITDVIPSEAINELTVLVLVNTIYFKGLWKSKFSPENTRKELFYKADGESCSASMMYQEGK 289

Query: 241 LNIGYIEDLKAQILELPYAG-DVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299
                + +   Q+LELP+ G D++M L+LP         L  +E E+T + L +W   D+
Sbjct: 290 FRYRRVAE-GTQVLELPFKGDDITMVLILPKP----EKSLAKVEKELTPEVLQEWL--DE 342

Query: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGM--SERNDLFLSEVFHQ 357
           + E  + V++P+F++E+ + L+  L+ MG+ D F+  ++   G+    R+DL++S+ FH+
Sbjct: 343 LEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHK 402

Query: 358 AMVDVNEEGTEAAAGTGGVMTGRT-GHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
           A ++VNEEG+EAAA T  V+ GR+       F A+ PFL  I     N I+F GR ++P
Sbjct: 403 AFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRVANP 461


>gi|73623033 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 8 isoform b [Homo sapiens]
          Length = 242

 Score =  197 bits (502), Expect = 1e-50
 Identities = 109/277 (39%), Positives = 159/277 (57%), Gaps = 39/277 (14%)

Query: 1   MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
           M+DLC AN  FA++LFK L +   ++N+F SP SISS +AMV+MG++GST  QM++ L  
Sbjct: 1   MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60

Query: 61  NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
            + G                                      IH  F+SL S +N +   
Sbjct: 61  YKDG-------------------------------------DIHRGFQSLLSEVNRTGTQ 83

Query: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
           YLL + N+LFGEK+  F  ++   CQK+Y +E + + F E  EE RK IN WV  +T+GK
Sbjct: 84  YLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGK 143

Query: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
           I  +L  G+VD  T++VLVNA+YFKGKW   F++K      F+ N  ++T VQMM+   K
Sbjct: 144 ISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFKTNEEKKT-VQMMFKEAK 202

Query: 241 LNIGYIEDLKAQILELPYA-GDVSMFLLLPDEIADVS 276
             +GY +++  Q+LELPY   ++SM +LLPD+  D++
Sbjct: 203 FKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLA 239


>gi|170295807 neuroserpin precursor [Homo sapiens]
          Length = 410

 Score =  195 bits (496), Expect = 6e-50
 Identities = 116/411 (28%), Positives = 211/411 (51%), Gaps = 50/411 (12%)

Query: 12  ALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAVTPM 71
           ++N++  L      +N+  SP SI+  M M+ +G++GST+ ++   + ++ +        
Sbjct: 30  SVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSL-------- 81

Query: 72  TPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVNKLFG 131
             +N     F+++                          S+ + A    Y+++  N LF 
Sbjct: 82  --KNGEEFSFLKEF-------------------------SNMVTAKESQYVMKIANSLFV 114

Query: 132 EKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSVD 191
           +      EE++++ +KY+++    VDF +    A   IN WV+  T   + +L+     D
Sbjct: 115 QNGFHVNEEFLQMMKKYFNAAVNHVDFSQNVAVANY-INKWVENNTNNLVKDLVSPRDFD 173

Query: 192 GDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIEDLKA 251
             T + L+NAVYFKG WK+ F  +    + F  +      + MMY + +   G   D   
Sbjct: 174 AATYLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSN 233

Query: 252 ------QILELPYAGD-VSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDE 304
                 Q+LE+PY GD +SM L+L  +   ++T   L+++++    + +W +  K  + +
Sbjct: 234 EAGGIYQVLEIPYEGDEISMMLVLSRQEVPLATLEPLVKAQL----VEEWANSVK--KQK 287

Query: 305 VEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNE 364
           VEVY+P+F +E+  +L+ +L+++G+ + F K  AN +G+S+  ++FLS+  H++ ++VNE
Sbjct: 288 VEVYLPRFTVEQEIDLKDVLKALGITEIFIKD-ANLTGLSDNKEIFLSKAIHKSFLEVNE 346

Query: 365 EGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
           EG+EAAA +G +   R     PQ + DHPF FLI ++ T  ILF GR   P
Sbjct: 347 EGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFLIRNRRTGTILFMGRVMHP 397


>gi|4826904 neuroserpin precursor [Homo sapiens]
          Length = 410

 Score =  195 bits (496), Expect = 6e-50
 Identities = 116/411 (28%), Positives = 211/411 (51%), Gaps = 50/411 (12%)

Query: 12  ALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAVTPM 71
           ++N++  L      +N+  SP SI+  M M+ +G++GST+ ++   + ++ +        
Sbjct: 30  SVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSL-------- 81

Query: 72  TPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVNKLFG 131
             +N     F+++                          S+ + A    Y+++  N LF 
Sbjct: 82  --KNGEEFSFLKEF-------------------------SNMVTAKESQYVMKIANSLFV 114

Query: 132 EKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSVD 191
           +      EE++++ +KY+++    VDF +    A   IN WV+  T   + +L+     D
Sbjct: 115 QNGFHVNEEFLQMMKKYFNAAVNHVDFSQNVAVANY-INKWVENNTNNLVKDLVSPRDFD 173

Query: 192 GDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIEDLKA 251
             T + L+NAVYFKG WK+ F  +    + F  +      + MMY + +   G   D   
Sbjct: 174 AATYLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSN 233

Query: 252 ------QILELPYAGD-VSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDE 304
                 Q+LE+PY GD +SM L+L  +   ++T   L+++++    + +W +  K  + +
Sbjct: 234 EAGGIYQVLEIPYEGDEISMMLVLSRQEVPLATLEPLVKAQL----VEEWANSVK--KQK 287

Query: 305 VEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNE 364
           VEVY+P+F +E+  +L+ +L+++G+ + F K  AN +G+S+  ++FLS+  H++ ++VNE
Sbjct: 288 VEVYLPRFTVEQEIDLKDVLKALGITEIFIKD-ANLTGLSDNKEIFLSKAIHKSFLEVNE 346

Query: 365 EGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
           EG+EAAA +G +   R     PQ + DHPF FLI ++ T  ILF GR   P
Sbjct: 347 EGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFLIRNRRTGTILFMGRVMHP 397


>gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member 2
           [Homo sapiens]
          Length = 405

 Score =  189 bits (480), Expect = 4e-48
 Identities = 122/411 (29%), Positives = 213/411 (51%), Gaps = 47/411 (11%)

Query: 8   NTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANA 67
           NT FA++L++ ++  S   N+  SP  I+  + MV +G++G  + Q+ + L+  E  A  
Sbjct: 26  NTEFAVDLYQEVS-LSHKDNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSAGE 84

Query: 68  VTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVN 127
                 E F                               +S  SAI+     +     N
Sbjct: 85  ------EFFV-----------------------------LKSFFSAISEKKQEFTFNLAN 109

Query: 128 KLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPE 187
            L+ ++  + +E+Y+   ++++ S  + VDF + A+   + I++WV+ +T GKI ++   
Sbjct: 110 ALYLQEGFTVKEQYLHGNKEFFQSAIKLVDFQD-AKACAEMISTWVERKTDGKIKDMFSG 168

Query: 188 GSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIE 247
                 TR+VLVNA+YFKG WK  F K+   L  F   +     + MM    +   GY  
Sbjct: 169 EEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQLINFTKKNGSTVKIPMMKALLRTKYGYFS 228

Query: 248 D--LKAQILELPYAGD-VSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDE 304
           +  L  Q+LEL Y GD  S+ ++LP E  D+    E +E  IT  ++ KW S  +M E+E
Sbjct: 229 ESSLNYQVLELSYKGDEFSLIIILPAEGMDI----EEVEKLITAQQILKWLS--EMQEEE 282

Query: 305 VEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNE 364
           VE+ +P+FK+E+  + + +L S+ + + F+ G  + SG+++ +++++S+V  +   ++NE
Sbjct: 283 VEISLPRFKVEQKVDFKDVLYSLNITEIFS-GGCDLSGITDSSEVYVSQVTQKVFFEINE 341

Query: 365 EGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
           +G+EAA  TG  +         QF+A+HPFLF++ H  T  ILF GR ++P
Sbjct: 342 DGSEAATSTGIHIPVIMSLAQSQFIANHPFLFIMKHNPTESILFMGRVTNP 392


>gi|110225347 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 9 isoform
           A [Homo sapiens]
          Length = 435

 Score =  186 bits (473), Expect = 3e-47
 Identities = 125/411 (30%), Positives = 212/411 (51%), Gaps = 47/411 (11%)

Query: 8   NTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANA 67
           NT FA  L++ L   +P+QN+F SP S+S+++AM+ +G+   T+ Q+ + L FN      
Sbjct: 66  NTDFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFN------ 119

Query: 68  VTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVN 127
               TPE+                           IH  F+ L  ++   + +  L+  +
Sbjct: 120 -LTHTPES--------------------------AIHQGFQHLVHSLTVPSKDLTLKMGS 152

Query: 128 KLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPE 187
            LF +K    +  ++   ++ Y +E  + DF      A+ +INS VK +T+GK+ +++  
Sbjct: 153 ALFVKKELQLQANFLGNVKRLYEAEVFSTDFSN-PSIAQARINSHVKKKTQGKVVDIIQ- 210

Query: 188 GSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGL-YPFRVNSAQRTPVQMMYLREKLNIGYI 246
             +D  T MVLVN ++FK KW+ PF  +     +PF V       V MM+ +E+   G  
Sbjct: 211 -GLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVHVPMMHQKEQFAFGVD 269

Query: 247 EDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDEVE 306
            +L   +L++ Y GD   F +LP +       +  LE  ++   L KW+    + +  +E
Sbjct: 270 TELNCFVLQMDYKGDAVAFFVLPSK-----GKMRQLEQALSARTLRKWS--HSLQKRWIE 322

Query: 307 VYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNEEG 366
           V+IP+F +   Y L +IL  MG+++ F+K  A+FSG+++R+ L +S+  H+A++DV+EEG
Sbjct: 323 VFIPRFSISASYNLETILPKMGIQNVFDK-NADFSGIAKRDSLQVSKATHKAVLDVSEEG 381

Query: 367 TEAAAGTGGVMTGRTGHGGPQFVA--DHPFLFLIMHKITNCILFFGRFSSP 415
           TEA A T      R+  G   F    +  FL +I +K T+ ILF G+  +P
Sbjct: 382 TEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVENP 432


>gi|50659080 serpin peptidase inhibitor, clade A, member 3 precursor
           [Homo sapiens]
          Length = 423

 Score =  183 bits (464), Expect = 3e-46
 Identities = 128/417 (30%), Positives = 213/417 (51%), Gaps = 50/417 (11%)

Query: 4   LCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEV 63
           L  AN  FA +L+K L   +P +N+  SP SIS+ +A + +G+  +T  ++ K L+FN  
Sbjct: 49  LASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFN-- 106

Query: 64  GANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLL 123
                                          L   +  +IH SF+ L   +N S+    L
Sbjct: 107 -------------------------------LTETSEAEIHQSFQHLLRTLNQSSDELQL 135

Query: 124 ESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPN 183
              N +F ++  S  + +    ++ Y SE  A DF + A  A+K IN +VK  T+GKI +
Sbjct: 136 SMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAA-AKKLINDYVKNGTRGKITD 194

Query: 184 LLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNI 243
           L+ +  +D  T MVLVN ++FK KW+ PF+ +      F ++  +   V MM L   L I
Sbjct: 195 LIKD--LDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMMSLHH-LTI 251

Query: 244 GYI--EDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMA 301
            Y   E+L   ++EL Y G+ S   +LPD+       +E +E+ +  + L +W  +D + 
Sbjct: 252 PYFRDEELSCTVVELKYTGNASALFILPDQ-----DKMEEVEAMLLPETLKRW--RDSLE 304

Query: 302 EDEV-EVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMV 360
             E+ E+Y+P+F +   Y L  IL  +G+E+AF   +A+ SG++   +L +S+V H+A++
Sbjct: 305 FREIGELYLPKFSISRDYNLNDILLQLGIEEAFTS-KADLSGITGARNLAVSQVVHKAVL 363

Query: 361 DVNEEGTEAAAGTGGVMTGRTGHGGPQFVA--DHPFLFLIMHKITNCILFFGRFSSP 415
           DV EEGTEA+A T   +T  +     + +   + PFL +I+   T  I F  + ++P
Sbjct: 364 DVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNP 420


>gi|73858566 heparin cofactor II precursor [Homo sapiens]
          Length = 499

 Score =  180 bits (456), Expect = 2e-45
 Identities = 129/421 (30%), Positives = 212/421 (50%), Gaps = 53/421 (12%)

Query: 1   MEDLCVANTLFALNLFKHLAKASPT-QNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQ 59
           ++ L + N  FA NL++ L     T  N+F++P  IS+ M M+ +G +G T +Q+  +L 
Sbjct: 123 IQRLNILNAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILH 182

Query: 60  FNE-VGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINAST 118
           F + V A++   +T                              IH+ FR L+  +    
Sbjct: 183 FKDFVNASSKYEITT-----------------------------IHNLFRKLTHRLFRRN 213

Query: 119 GNYLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTK 178
             Y L SVN L+ +K      ++    ++YY +E Q  DF + A  +  K N+ +   TK
Sbjct: 214 FGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEAQIADFSDPAFIS--KTNNHIMKLTK 271

Query: 179 GKIPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLR 238
           G I + L   ++D  T+M+++N +YFKG W   F  ++   + FR+N  +   V MM  +
Sbjct: 272 GLIKDALE--NIDPATQMMILNCIYFKGSWVNKFPVEMTHNHNFRLNEREVVKVSMMQTK 329

Query: 239 EKLNIGYIEDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKD 298
                   ++L   IL+L Y G +SM +++P ++    +G++ LE+++T   + +W  + 
Sbjct: 330 GNFLAANDQELDCDILQLEYVGGISMLIVVPHKM----SGMKTLEAQLTPRVVERW--QK 383

Query: 299 KMAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERN---DLFLSEVF 355
            M     EV +P+FKLE++Y L   L+ MG+   F+K   N +G+S++    DLF     
Sbjct: 384 SMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDK-NGNMAGISDQRIAIDLFK---- 438

Query: 356 HQAMVDVNEEGTEA-AAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSS 414
           HQ  + VNEEGT+A    T G M   T     +F  D PFLFLI    T+C+LF GR ++
Sbjct: 439 HQGTITVNEEGTQATTVTTVGFMPLST---QVRFTVDRPFLFLIYEHRTSCLLFMGRVAN 495

Query: 415 P 415
           P
Sbjct: 496 P 496


>gi|194018472 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 5 [Homo
           sapiens]
          Length = 406

 Score =  179 bits (453), Expect = 5e-45
 Identities = 122/423 (28%), Positives = 214/423 (50%), Gaps = 55/423 (13%)

Query: 1   MEDLCVANTL-------FALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQ 53
           +EDL V  T+       F  +L++ LA A+P+Q++F SP SIS ++AM+ +G+  ST+ Q
Sbjct: 31  VEDLHVGATVAPSSRRDFTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQ 90

Query: 54  MAKVLQFNEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSA 113
           + + L  N                                 LQ  +  ++H  F+ L   
Sbjct: 91  ILEGLGLN---------------------------------LQKSSEKELHRGFQQLLQE 117

Query: 114 INASTGNYLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWV 173
           +N     + L   N LF +     ++ ++   +  Y ++    +F + A  A K+IN +V
Sbjct: 118 LNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAG-AMKQINDYV 176

Query: 174 KTQTKGKIPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQ 233
             QTKGKI +LL   ++D +  +++VN ++FK KW+T F  K      F V S     V 
Sbjct: 177 AKQTKGKIVDLLK--NLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVP 234

Query: 234 MMYLREKLNIGYIEDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNK 293
           MM   ++ +     +L  +++ +PY G+ +   +LP E       ++ +E+ ++   L K
Sbjct: 235 MMSREDQYHYLLDRNLSCRVVGVPYQGNATALFILPSE-----GKMQQVENGLSEKTLRK 289

Query: 294 WTSKDKMAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSE 353
           W    K  + ++E+Y+P+F +E  Y+L  +L S+G+ + F    A+ SG+S  +++ +SE
Sbjct: 290 WLKMFK--KRQLELYLPKFSIEGSYQLEKVLPSLGISNVFT-SHADLSGISNHSNIQVSE 346

Query: 354 VFHQAMVDVNEEGTEAAAGTGGVMTGRTGH-GGPQFVADHPFLFLIMHKITNCILFFGRF 412
           + H+A+V+V+E GT AAA TG + T R+      + V + PFL  I   + N ILF G+ 
Sbjct: 347 MVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFI---VDNNILFLGKV 403

Query: 413 SSP 415
           + P
Sbjct: 404 NRP 406


>gi|189163542 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  174 bits (441), Expect = 1e-43
 Identities = 120/405 (29%), Positives = 203/405 (50%), Gaps = 46/405 (11%)

Query: 11  FALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAVTP 70
           FA +L++ LA  S + N+F SP SI++  AM+ +G++  T D++ + L FN         
Sbjct: 57  FAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLT------- 109

Query: 71  MTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVNKLF 130
                               P+A        +IH  F+ L   +N       L + N LF
Sbjct: 110 ------------------EIPEA--------QIHEGFQELLRTLNQPDSQLQLTTGNGLF 143

Query: 131 GEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSV 190
             +     ++++   +K Y SE   V+F +  EEA+K+IN +V+  T+GKI +L+ E  +
Sbjct: 144 LSEGLKLVDKFLEDVKKLYHSEAFTVNFGD-TEEAKKQINDYVEKGTQGKIVDLVKE--L 200

Query: 191 DGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIEDLK 250
           D DT   LVN ++FKGKW+ PFE K      F V+      V MM      NI + + L 
Sbjct: 201 DRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLS 260

Query: 251 AQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDEVEVYIP 310
           + +L + Y G+ +    LPDE       L+ LE+E+T+D + K+   +        +++P
Sbjct: 261 SWVLLMKYLGNATAIFFLPDE-----GKLQHLENELTHDIITKFLENED--RRSASLHLP 313

Query: 311 QFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNEEGTEAA 370
           +  +   Y+L+S+L  +G+   F+ G A+ SG++E   L LS+  H+A++ ++E+GTEAA
Sbjct: 314 KLSITGTYDLKSVLGQLGITKVFSNG-ADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAA 372

Query: 371 AGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
                 +        P+   + PF+FL++ + T   LF G+  +P
Sbjct: 373 GAM--FLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415


>gi|189163540 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  174 bits (441), Expect = 1e-43
 Identities = 120/405 (29%), Positives = 203/405 (50%), Gaps = 46/405 (11%)

Query: 11  FALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAVTP 70
           FA +L++ LA  S + N+F SP SI++  AM+ +G++  T D++ + L FN         
Sbjct: 57  FAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLT------- 109

Query: 71  MTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVNKLF 130
                               P+A        +IH  F+ L   +N       L + N LF
Sbjct: 110 ------------------EIPEA--------QIHEGFQELLRTLNQPDSQLQLTTGNGLF 143

Query: 131 GEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSV 190
             +     ++++   +K Y SE   V+F +  EEA+K+IN +V+  T+GKI +L+ E  +
Sbjct: 144 LSEGLKLVDKFLEDVKKLYHSEAFTVNFGD-TEEAKKQINDYVEKGTQGKIVDLVKE--L 200

Query: 191 DGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIEDLK 250
           D DT   LVN ++FKGKW+ PFE K      F V+      V MM      NI + + L 
Sbjct: 201 DRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLS 260

Query: 251 AQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDEVEVYIP 310
           + +L + Y G+ +    LPDE       L+ LE+E+T+D + K+   +        +++P
Sbjct: 261 SWVLLMKYLGNATAIFFLPDE-----GKLQHLENELTHDIITKFLENED--RRSASLHLP 313

Query: 311 QFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNEEGTEAA 370
           +  +   Y+L+S+L  +G+   F+ G A+ SG++E   L LS+  H+A++ ++E+GTEAA
Sbjct: 314 KLSITGTYDLKSVLGQLGITKVFSNG-ADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAA 372

Query: 371 AGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
                 +        P+   + PF+FL++ + T   LF G+  +P
Sbjct: 373 GAM--FLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415


>gi|189163538 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  174 bits (441), Expect = 1e-43
 Identities = 120/405 (29%), Positives = 203/405 (50%), Gaps = 46/405 (11%)

Query: 11  FALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAVTP 70
           FA +L++ LA  S + N+F SP SI++  AM+ +G++  T D++ + L FN         
Sbjct: 57  FAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLT------- 109

Query: 71  MTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVNKLF 130
                               P+A        +IH  F+ L   +N       L + N LF
Sbjct: 110 ------------------EIPEA--------QIHEGFQELLRTLNQPDSQLQLTTGNGLF 143

Query: 131 GEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSV 190
             +     ++++   +K Y SE   V+F +  EEA+K+IN +V+  T+GKI +L+ E  +
Sbjct: 144 LSEGLKLVDKFLEDVKKLYHSEAFTVNFGD-TEEAKKQINDYVEKGTQGKIVDLVKE--L 200

Query: 191 DGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIEDLK 250
           D DT   LVN ++FKGKW+ PFE K      F V+      V MM      NI + + L 
Sbjct: 201 DRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLS 260

Query: 251 AQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDEVEVYIP 310
           + +L + Y G+ +    LPDE       L+ LE+E+T+D + K+   +        +++P
Sbjct: 261 SWVLLMKYLGNATAIFFLPDE-----GKLQHLENELTHDIITKFLENED--RRSASLHLP 313

Query: 311 QFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNEEGTEAA 370
           +  +   Y+L+S+L  +G+   F+ G A+ SG++E   L LS+  H+A++ ++E+GTEAA
Sbjct: 314 KLSITGTYDLKSVLGQLGITKVFSNG-ADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAA 372

Query: 371 AGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
                 +        P+   + PF+FL++ + T   LF G+  +P
Sbjct: 373 GAM--FLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415


>gi|189163536 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  174 bits (441), Expect = 1e-43
 Identities = 120/405 (29%), Positives = 203/405 (50%), Gaps = 46/405 (11%)

Query: 11  FALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAVTP 70
           FA +L++ LA  S + N+F SP SI++  AM+ +G++  T D++ + L FN         
Sbjct: 57  FAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLT------- 109

Query: 71  MTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVNKLF 130
                               P+A        +IH  F+ L   +N       L + N LF
Sbjct: 110 ------------------EIPEA--------QIHEGFQELLRTLNQPDSQLQLTTGNGLF 143

Query: 131 GEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSV 190
             +     ++++   +K Y SE   V+F +  EEA+K+IN +V+  T+GKI +L+ E  +
Sbjct: 144 LSEGLKLVDKFLEDVKKLYHSEAFTVNFGD-TEEAKKQINDYVEKGTQGKIVDLVKE--L 200

Query: 191 DGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIEDLK 250
           D DT   LVN ++FKGKW+ PFE K      F V+      V MM      NI + + L 
Sbjct: 201 DRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLS 260

Query: 251 AQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDEVEVYIP 310
           + +L + Y G+ +    LPDE       L+ LE+E+T+D + K+   +        +++P
Sbjct: 261 SWVLLMKYLGNATAIFFLPDE-----GKLQHLENELTHDIITKFLENED--RRSASLHLP 313

Query: 311 QFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNEEGTEAA 370
           +  +   Y+L+S+L  +G+   F+ G A+ SG++E   L LS+  H+A++ ++E+GTEAA
Sbjct: 314 KLSITGTYDLKSVLGQLGITKVFSNG-ADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAA 372

Query: 371 AGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
                 +        P+   + PF+FL++ + T   LF G+  +P
Sbjct: 373 GAM--FLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415


>gi|189163534 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  174 bits (441), Expect = 1e-43
 Identities = 120/405 (29%), Positives = 203/405 (50%), Gaps = 46/405 (11%)

Query: 11  FALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAVTP 70
           FA +L++ LA  S + N+F SP SI++  AM+ +G++  T D++ + L FN         
Sbjct: 57  FAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLT------- 109

Query: 71  MTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVNKLF 130
                               P+A        +IH  F+ L   +N       L + N LF
Sbjct: 110 ------------------EIPEA--------QIHEGFQELLRTLNQPDSQLQLTTGNGLF 143

Query: 131 GEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSV 190
             +     ++++   +K Y SE   V+F +  EEA+K+IN +V+  T+GKI +L+ E  +
Sbjct: 144 LSEGLKLVDKFLEDVKKLYHSEAFTVNFGD-TEEAKKQINDYVEKGTQGKIVDLVKE--L 200

Query: 191 DGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIEDLK 250
           D DT   LVN ++FKGKW+ PFE K      F V+      V MM      NI + + L 
Sbjct: 201 DRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLS 260

Query: 251 AQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDEVEVYIP 310
           + +L + Y G+ +    LPDE       L+ LE+E+T+D + K+   +        +++P
Sbjct: 261 SWVLLMKYLGNATAIFFLPDE-----GKLQHLENELTHDIITKFLENED--RRSASLHLP 313

Query: 311 QFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNEEGTEAA 370
           +  +   Y+L+S+L  +G+   F+ G A+ SG++E   L LS+  H+A++ ++E+GTEAA
Sbjct: 314 KLSITGTYDLKSVLGQLGITKVFSNG-ADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAA 372

Query: 371 AGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
                 +        P+   + PF+FL++ + T   LF G+  +P
Sbjct: 373 GAM--FLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,675,209
Number of Sequences: 37866
Number of extensions: 605995
Number of successful extensions: 1738
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 64
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 1438
Number of HSP's gapped (non-prelim): 122
length of query: 415
length of database: 18,247,518
effective HSP length: 105
effective length of query: 310
effective length of database: 14,271,588
effective search space: 4424192280
effective search space used: 4424192280
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.